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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2123536
log Bayes Factor = 0.115873
Chromosome 2   position 19,945,577  (GRCh37) Explore rs2123536 on Ensembl!
Variant rs2123536 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20.8 Other forms of angina pectoris
0.000 0.825 0.175
I25.1 Atherosclerotic heart disease
0.000 0.827 0.173
I20 Angina pectoris
0.000 0.840 0.160
I20-I25 Ischaemic heart diseases
0.000 0.855 0.145
I25 Chronic ischaemic heart disease
0.000 0.858 0.142
I20.9 Angina pectoris, unspecified
0.000 0.861 0.139
I20.1 Angina pectoris with documented spasm
0.000 0.884 0.116
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.886 0.114
I21 Acute myocardial infarction
0.000 0.886 0.114
I23 Certain current complications following acute myocardial infarction
0.000 0.894 0.106
I24 Other acute ischaemic heart diseases
0.000 0.895 0.105
I25.4 Coronary artery aneurysm
0.000 0.895 0.105
I25.6 Silent myocardial ischaemia
0.000 0.898 0.102
I25.3 Aneurysm of heart
0.000 0.899 0.101
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.906 0.094
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.909 0.091
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.911 0.089
I20.0 Unstable angina
0.000 0.911 0.089
I22 Subsequent myocardial infarction
0.000 0.912 0.088
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.916 0.084
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.918 0.082
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.918 0.082
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.921 0.079
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.922 0.078
I23.8 Other current complications following acute myocardial infarction
0.000 0.923 0.077
I25.5 Ischaemic cardiomyopathy
0.000 0.923 0.076
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.923 0.076
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.923 0.076
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.923 0.076
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.923 0.076
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.923 0.076
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.923 0.076
I24.1 Dressler's syndrome
0.000 0.926 0.074
I22.8 Subsequent myocardial infarction of other sites
0.000 0.933 0.067
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.938 0.061
I21.4 Acute subendocardial myocardial infarction
0.000 0.942 0.057
I25.2 Old myocardial infarction
0.000 0.943 0.057
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.943 0.056
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.945 0.055
N20 Calculus of kidney and ureter
0.054 0.946 0.000
N20.1 Calculus of ureter
0.053 0.947 0.000
I60-I69 Cerebrovascular diseases
0.000 0.948 0.052
Chapter IX Diseases of the circulatory system
0.000 0.949 0.051
N20-N23 Urolithiasis
0.051 0.949 0.000
N23 Unspecified renal colic
0.051 0.949 0.000
N20.2 Calculus of kidney with calculus of ureter
0.051 0.949 0.000
I63 Cerebral infarction
0.000 0.950 0.050
I10-I15 Hypertensive diseases
0.000 0.952 0.048
I67 Other cerebrovascular diseases
0.000 0.954 0.046
N21 Calculus of lower urinary tract
0.045 0.955 0.000
I63.9 Cerebral infarction, unspecified
0.000 0.956 0.044
I61 Intracerebral haemorrhage
0.000 0.956 0.044
N20.0 Calculus of kidney
0.044 0.956 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.957 0.043
I10 Essential (primary) hypertension
0.000 0.957 0.043
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.958 0.042
I15 Secondary hypertension
0.000 0.958 0.042
I24.8 Other forms of acute ischaemic heart disease
0.000 0.959 0.041
I67.8 Other specified cerebrovascular diseases
0.000 0.959 0.041
I60 Subarachnoid haemorrhage
0.000 0.960 0.040
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.961 0.039
I63.8 Other cerebral infarction
0.000 0.961 0.039
N20.9 Urinary calculus, unspecified
0.038 0.961 0.000
N21.0 Calculus in bladder
0.038 0.962 0.000
I00-I02 Acute rheumatic fever
0.000 0.962 0.037
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.962 0.038
I67.1 Cerebral aneurysm, nonruptured
0.000 0.963 0.037
I12 Hypertensive renal disease
0.000 0.963 0.037
N22 Calculus of urinary tract in diseases classified elsewhere
0.037 0.963 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.963 0.037
I67.9 Cerebrovascular disease, unspecified
0.000 0.963 0.037
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.963 0.037
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.963 0.036
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.964 0.036
I15.1 Hypertension secondary to other renal disorders
0.000 0.964 0.036
I13 Hypertensive heart and renal disease
0.000 0.964 0.036
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.964 0.036
I69 Sequelae of cerebrovascular disease
0.000 0.964 0.036
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.965 0.035
I68.0 Cerebral amyloid angiopathy
0.000 0.965 0.035
I11 Hypertensive heart disease
0.000 0.965 0.035
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.965 0.034
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.966 0.034
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.966 0.034
N21.1 Calculus in urethra
0.034 0.966 0.000
I62 Other nontraumatic intracranial haemorrhage
0.000 0.966 0.034
I67.4 Hypertensive encephalopathy
0.000 0.966 0.034
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.966 0.034
I67.5 Moyamoya disease
0.000 0.967 0.033
I67.3 Progressive vascular leukoencephalopathy
0.000 0.967 0.033
N21.8 Other lower urinary tract calculus
0.033 0.967 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.033 0.967 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.967 0.033
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.967 0.033
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.967 0.033
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.967 0.032
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.968 0.032
I15.8 Other secondary hypertension
0.000 0.968 0.031
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.968 0.031
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.969 0.031
I60.8 Other subarachnoid haemorrhage
0.000 0.969 0.031
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.969 0.031
I12.9 Hypertensive renal disease without renal failure
0.000 0.969 0.031
I15.9 Seconday hypertension, unspecified
0.000 0.969 0.031
I15.0 Renovascular hypertension
0.000 0.969 0.031
I69.3 Sequelae of cerebral infarction
0.000 0.970 0.030
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.970 0.030
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.970 0.030
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.970 0.030
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.970 0.030
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.970 0.030
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.970 0.029
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.971 0.029
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.971 0.029
I15.2 Hypertension secondary to endocrine disorders
0.000 0.971 0.029
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.971 0.029
I61.8 Other intracerebral haemorrhage
0.000 0.971 0.029
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.972 0.028
I00 Rheumatic fever without mention of heart involvement
0.000 0.972 0.027
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.973 0.027
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.973 0.027
I02 Rheumatic chorea
0.000 0.973 0.027
I01 Rheumatic fever with heart involvement
0.000 0.973 0.027
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.973 0.027
N22.8 Calculus of urinary tract in other diseases classified elsewhere
0.027 0.973 0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]
0.027 0.973 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.973 0.026
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.974 0.026
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.974 0.026
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.974 0.026
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.974 0.026
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.974 0.026
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.974 0.026
I67.2 Cerebral atherosclerosis
0.000 0.974 0.026
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.974 0.026
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.974 0.026
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.974 0.026
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.974 0.026
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.974 0.025
I21.9 Acute myocardial infarction, unspecified
0.000 0.975 0.025
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.975 0.025
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.975 0.025
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.975 0.025
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.975 0.025
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.976 0.024
I05-I09 Chronic rheumatic heart diseases
0.000 0.976 0.024
I62.1 Nontraumatic extradural haemorrhage
0.000 0.976 0.024
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.976 0.024
I30-I52 Other forms of heart disease
0.000 0.976 0.024
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.977 0.023
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.977 0.023
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.977 0.023
I34 Nonrheumatic mitral valve disorders
0.000 0.977 0.023
I12.0 Hypertensive renal disease with renal failure
0.000 0.977 0.023
I95 Hypotension
0.000 0.977 0.023
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.978 0.022
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.978 0.022
I99 Other and unspecified disorders of circulatory system
0.000 0.979 0.021
I95.1 Orthostatic hypotension
0.000 0.979 0.021
I45 Other conduction disorders
0.000 0.979 0.021
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.980 0.020
I34.1 Mitral (valve) prolapse
0.000 0.980 0.020
I49 Other cardiac arrhythmias
0.000 0.980 0.020
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.980 0.020
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.980 0.019
I01.8 Other acute rheumatic heart disease
0.000 0.980 0.019
I01.2 Acute rheumatic myocarditis
0.000 0.980 0.019
I01.1 Acute rheumatic endocarditis
0.000 0.980 0.019
I01.0 Acute rheumatic pericarditis
0.000 0.980 0.019
I02.9 Rheumatic chorea without heart involvement
0.000 0.980 0.019
I02.0 Rheumatic chorea with heart involvement
0.000 0.980 0.019
J90 Pleural effusion, not elsewhere classified
0.000 0.980 0.020
I05 Rheumatic mitral valve diseases
0.000 0.981 0.019
J90-J94 Other diseases of pleura
0.000 0.981 0.019
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.981 0.019
I34.0 Mitral (valve) insufficiency
0.000 0.981 0.019
I45.2 Bifascicular block
0.000 0.981 0.019
J92 Pleural plaque
0.000 0.981 0.019
I86 Varicose veins of other sites
0.000 0.981 0.019
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.981 0.018
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.981 0.019
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.981 0.019
I38 Endocarditis, valve unspecified
0.000 0.981 0.019
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.981 0.019
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.981 0.018
J92.0 Pleural plaque with presence of asbestos
0.000 0.982 0.018
I49.0 Ventricular fibrillation and flutter
0.000 0.982 0.018
I46 Cardiac arrest
0.000 0.982 0.018
I30 Acute pericarditis
0.000 0.982 0.018
I40 Acute myocarditis
0.000 0.982 0.018
I65.1 Occlusion and stenosis of basilar artery
0.000 0.982 0.017
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.982 0.017
J91 Pleural effusion in conditions classified elsewhere
0.000 0.982 0.017
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.983 0.017
I09 Other rheumatic heart diseases
0.000 0.983 0.017
I52 Other heart disorders in diseases classified elsewhere
0.000 0.983 0.017
I48 Atrial fibrillation and flutter
0.000 0.983 0.017
I41 Myocarditis in diseases classified elsewhere
0.000 0.983 0.017
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.983 0.017
I32 Pericarditis in diseases classified elsewhere
0.000 0.983 0.017
J94 Other pleural conditions
0.000 0.983 0.017
I89.0 Lymphoedema, not elsewhere classified
0.000 0.983 0.017
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.983 0.017
I06 Rheumatic aortic valve diseases
0.000 0.983 0.017
I05.9 Mitral valve disease, unspecified
0.000 0.983 0.017
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.983 0.017
I45.5 Other specified heart block
0.000 0.983 0.017
I28 Other diseases of pulmonary vessels
0.000 0.983 0.017
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.983 0.017
I49.3 Ventricular premature depolarisation
0.000 0.983 0.017
I86.1 Scrotal varices
0.000 0.983 0.016
I45.6 Preexcitation syndrome
0.000 0.984 0.016
I37 Pulmonary valve disorders
0.000 0.984 0.016
I82 Other venous embolism and thrombosis
0.000 0.984 0.016
I97.1 Other functional disturbances following cardiac surgery
0.000 0.984 0.016
I88 Nonspecific lymphadenitis
0.000 0.984 0.016
I45.8 Other specified conduction disorders
0.000 0.984 0.016
I95.0 Idiopathic hypotension
0.000 0.984 0.016
I49.9 Cardiac arrhythmia, unspecified
0.000 0.984 0.016
I46.9 Cardiac arrest, unspecified
0.000 0.984 0.016
I89.1 Lymphangitis
0.000 0.984 0.015
I95.8 Other hypotension
0.000 0.984 0.015
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.984 0.015
I07 Rheumatic tricuspid valve diseases
0.000 0.985 0.015
I51 Complications and ill-defined descriptions of heart disease
0.000 0.985 0.015
I97.0 Postcardiotomy syndrome
0.000 0.985 0.015
J92.9 Pleural plaque without asbestos
0.000 0.985 0.015
I33 Acute and subacute endocarditis
0.000 0.985 0.015
I36 Nonrheumatic tricuspid valve disorders
0.000 0.985 0.015
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.985 0.015
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.985 0.015
I98.0 Cardiovascular syphilis
0.000 0.985 0.015
I05.1 Rheumatic mitral insufficiency
0.000 0.985 0.015
I45.1 Other and unspecified right bundle-branch block
0.000 0.985 0.015
I95.2 Hypotension due to drugs
0.000 0.985 0.015
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.985 0.015
I87 Other disorders of veins
0.000 0.985 0.015
I49.2 Junctional premature depolarisation
0.000 0.985 0.015
I35 Nonrheumatic aortic valve disorders
0.000 0.985 0.015
I86.8 Varicose veins of other specified sites
0.000 0.985 0.015
I27 Other pulmonary heart diseases
0.000 0.985 0.015
I45.0 Right fascicular block
0.000 0.985 0.014
I80 Phlebitis and thrombophlebitis
0.000 0.985 0.015
J94.2 Haemothorax
0.000 0.985 0.014
I30.9 Acute pericarditis, unspecified
0.000 0.986 0.014
I45.4 Nonspecific intraventricular block
0.000 0.986 0.014
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.986 0.014
I86.3 Vulval varices
0.000 0.986 0.014
I42 Cardiomyopathy
0.000 0.986 0.014
I50 Heart failure
0.000 0.986 0.014
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.986 0.014
J94.8 Other specified pleural conditions
0.000 0.986 0.014
I86.4 Gastric varices
0.000 0.986 0.014
I81 Portal vein thrombosis
0.000 0.986 0.014
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.986 0.014
I49.5 Sick sinus syndrome
0.000 0.986 0.014
I86.0 Sublingual varices
0.000 0.986 0.014
I86.2 Pelvic varices
0.000 0.986 0.014
J93 Pneumothorax
0.000 0.986 0.014
I49.8 Other specified cardiac arrhythmias
0.000 0.986 0.014
I30.8 Other forms of acute pericarditis
0.000 0.986 0.014
I05.8 Other mitral valve diseases
0.000 0.986 0.014
I40.0 Infective myocarditis
0.000 0.986 0.014
I05.0 Mitral stenosis
0.000 0.986 0.013
I47 Paroxysmal tachycardia
0.000 0.986 0.014
J94.1 Fibrothorax
0.000 0.987 0.013
I45.3 Trifascicular block
0.000 0.987 0.013
I85 Oesophageal varices
0.000 0.987 0.013
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.987 0.013
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.987 0.013
I45.9 Conduction disorder, unspecified
0.000 0.987 0.013
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.987 0.013
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.987 0.013
I40.8 Other acute myocarditis
0.000 0.987 0.013
I40.1 Isolated myocarditis
0.000 0.987 0.013
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.987 0.013
I49.1 Atrial premature depolarisation
0.000 0.987 0.013
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.987 0.013
I40.9 Acute myocarditis, unspecified
0.000 0.987 0.013
I49.4 Other and unspecified premature depolarisation
0.000 0.987 0.013
I46.1 Sudden cardiac death, so described
0.000 0.987 0.013
I50.0 Congestive heart failure
0.000 0.987 0.013
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.987 0.013
I82.8 Embolism and thrombosis of other specified veins
0.000 0.987 0.013
I09.8 Other specified rheumatic heart diseases
0.000 0.987 0.012
I09.2 Chronic rheumatic pericarditis
0.000 0.987 0.012
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.987 0.012
I09.0 Rheumatic myocarditis
0.000 0.987 0.012
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.987 0.013
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.987 0.013
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.987 0.013
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.987 0.013
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.987 0.013
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.987 0.013
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.987 0.013
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.987 0.013
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.987 0.013
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.987 0.013
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.987 0.013
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.987 0.013
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.987 0.013
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.987 0.013
I48.4 Atypical atrial flutter
0.000 0.987 0.013
I48.3 Typical atrial flutter
0.000 0.987 0.013
I48.2 Chronic atrial fibrillation
0.000 0.987 0.013
I48.1 Persistent atrial fibrillation
0.000 0.987 0.013
I48.0 Paroxysmal atrial fibrillation
0.000 0.987 0.013
I51.6 Cardiovascular disease, unspecified
0.000 0.987 0.013
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.987 0.013
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.987 0.013
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.987 0.013
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.987 0.012
J94.0 Chylous effusion
0.000 0.987 0.012
J94.9 Pleural condition, unspecified
0.000 0.987 0.012
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.987 0.012
I05.2 Mitral stenosis with insufficiency
0.000 0.987 0.012
I06.8 Other rheumatic aortic valve diseases
0.000 0.987 0.012
I65.2 Occlusion and stenosis of carotid artery
0.000 0.988 0.012
I09.9 Rheumatic heart disease, unspecified
0.000 0.988 0.012
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.988 0.012
I51.0 Cardiac septal defect, acquired
0.000 0.988 0.012
I06.1 Rheumatic aortic insufficiency
0.000 0.988 0.012
I95.9 Hypotension, unspecified
0.000 0.988 0.012
I28.1 Aneurysm of pulmonary artery
0.000 0.988 0.012
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.988 0.012
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.988 0.012
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.988 0.012
I27.8 Other specified pulmonary heart diseases
0.000 0.988 0.012
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.988 0.012
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.988 0.012
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.988 0.012
J93.8 Other pneumothorax
0.000 0.988 0.012
I37.9 Pulmonary valve disorder, unspecified
0.000 0.988 0.012
I37.8 Other pulmonary valve disorders
0.000 0.988 0.012
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.988 0.012
I82.1 Thrombophlebitis migrans
0.000 0.988 0.012
I37.0 Pulmonary valve stenosis
0.000 0.988 0.012
I82.0 Budd-Chiari syndrome
0.000 0.988 0.012
I82.3 Embolism and thrombosis of renal vein
0.000 0.988 0.012
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.988 0.012
I28.8 Other specified diseases of pulmonary vessels
0.000 0.988 0.011
I51.4 Myocarditis, unspecified
0.000 0.988 0.012
I88.8 Other nonspecific lymphadenitis
0.000 0.988 0.011
I30.1 Infective pericarditis
0.000 0.988 0.011
I06.0 Rheumatic aortic stenosis
0.000 0.988 0.011
I35.9 Aortic valve disorder, unspecified
0.000 0.989 0.011
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.989 0.011
I07.9 Tricuspid valve disease, unspecified
0.000 0.989 0.011
I07.8 Other tricuspid valve diseases
0.000 0.989 0.011
I07.2 Tricuspid stenosis with insufficiency
0.000 0.989 0.011
I07.0 Tricuspid stenosis
0.000 0.989 0.011
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.989 0.011
I46.0 Cardiac arrest with successful resuscitation
0.000 0.989 0.011
I51.5 Myocardial degeneration
0.000 0.989 0.011
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.989 0.011
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.989 0.011
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.989 0.011
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.989 0.011
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.989 0.011
I42.2 Other hypertrophic cardiomyopathy
0.000 0.989 0.011
I87.0 Postphlebitic syndrome
0.000 0.989 0.011
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.989 0.011
I42.5 Other restrictive cardiomyopathy
0.000 0.989 0.011
I37.1 Pulmonary valve insufficiency
0.000 0.989 0.011
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.989 0.011
I27.1 Kyphoscoliotic heart disease
0.000 0.989 0.011
I87.9 Disorder of vein, unspecified
0.000 0.989 0.010
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.989 0.011
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.989 0.011
J93.0 Spontaneous tension pneumothorax
0.000 0.989 0.010
I51.7 Cardiomegaly
0.000 0.989 0.011
I42.4 Endocardial fibroelastosis
0.000 0.989 0.010
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.990 0.010
I31 Other diseases of pericardium
0.000 0.990 0.010
I33.9 Acute endocarditis, unspecified
0.000 0.990 0.010
I47.0 Reentry ventricular arrhythmia
0.000 0.990 0.010
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.990 0.010
I35.8 Other aortic valve disorders
0.000 0.990 0.010
D12.8 Rectum
0.000 0.990 0.010
I42.6 Alcoholic cardiomyopathy
0.000 0.990 0.010
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.990 0.010
I35.1 Aortic (valve) insufficiency
0.000 0.990 0.010
I82.2 Embolism and thrombosis of vena cava
0.000 0.990 0.010
I85.0 Oesophageal varices with bleeding
0.000 0.990 0.010
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.990 0.010
I27.9 Pulmonary heart disease, unspecified
0.000 0.990 0.010
I42.8 Other cardiomyopathies
0.000 0.990 0.010
I33.0 Acute and subacute infective endocarditis
0.000 0.990 0.010
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.990 0.010
J93.9 Pneumothorax, unspecified
0.000 0.990 0.010
I51.9 Heart disease, unspecified
0.000 0.990 0.009
I27.2 Other secondary pulmonary hypertension
0.000 0.991 0.009
I87.1 Compression of vein
0.000 0.991 0.009
I27.0 Primary pulmonary hypertension
0.000 0.991 0.009
I26 Pulmonary embolism
0.000 0.991 0.009
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.991 0.009
I07.1 Tricuspid insufficiency
0.000 0.991 0.009
I42.0 Dilated cardiomyopathy
0.000 0.991 0.009
I51.8 Other ill-defined heart diseases
0.000 0.991 0.009
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.991 0.009
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.991 0.008
E78.5 Hyperlipidaemia, unspecified
0.000 0.991 0.009
Z95.1 Presence of aortocoronary bypass graft
0.000 0.991 0.009
Z95.0 Presence of cardiac pacemaker
0.000 0.992 0.008
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.992 0.008
I47.1 Supraventricular tachycardia
0.000 0.992 0.008
I50.9 Heart failure, unspecified
0.000 0.992 0.008
I47.2 Ventricular tachycardia
0.000 0.992 0.008
I77 Other disorders of arteries and arterioles
0.000 0.992 0.008
I83 Varicose veins of lower extremities
0.000 0.992 0.008
Z95.2 Presence of prosthetic heart valve
0.000 0.992 0.008
I31.8 Other specified diseases of pericardium
0.000 0.992 0.008
I31.2 Haemopericardium, not elsewhere classified
0.000 0.992 0.008
I08 Multiple valve diseases
0.000 0.992 0.008
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.992 0.008
I87.8 Other specified disorders of veins
0.000 0.992 0.007
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.993 0.007
I31.1 Chronic constrictive pericarditis
0.000 0.993 0.007
I71 Aortic aneurysm and dissection
0.000 0.993 0.007
I31.0 Chronic adhesive pericarditis
0.000 0.993 0.007
I42.9 Cardiomyopathy, unspecified
0.000 0.993 0.007
I85.9 Oesophageal varices without bleeding
0.000 0.993 0.007
J93.1 Other spontaneous pneumothorax
0.000 0.993 0.006
I31.3 Pericardial effusion (noninflammatory)
0.000 0.994 0.006
I70 Atherosclerosis
0.000 0.994 0.006
I77.0 Arteriovenous fistula, acquired
0.000 0.994 0.006
I77.1 Stricture of artery
0.000 0.994 0.006
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.994 0.006
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.994 0.006
I77.5 Necrosis of artery
0.000 0.994 0.006
I77.4 Coeliac artery compression syndrome
0.000 0.994 0.006
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.994 0.006
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.994 0.006
I71.0 Dissection of aorta [any part]
0.000 0.994 0.006
I77.2 Rupture of artery
0.000 0.994 0.006
Z95.3 Presence of xenogenic heart valve
0.000 0.994 0.006
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.994 0.006
I72 Other aneurysm
0.000 0.994 0.006
I77.3 Arterial fibromuscular dysplasia
0.000 0.994 0.006
I08.9 Multiple valve disease, unspecified
0.000 0.994 0.006
I74 Arterial embolism and thrombosis
0.000 0.994 0.006
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.994 0.006
I79.1 Aortitis in diseases classified elsewhere
0.000 0.994 0.005
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.994 0.005
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.994 0.005
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.994 0.005
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.994 0.005
I31.9 Disease of pericardium, unspecified
0.000 0.994 0.005
I77.8 Other specified disorders of arteries and arterioles
0.000 0.994 0.005
T43.2 Other and unspecified antidepressants
0.000 0.994 0.005
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.995 0.005
I08.0 Disorders of both mitral and aortic valves
0.000 0.995 0.005
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.995 0.005
I08.8 Other multiple valve diseases
0.000 0.995 0.005
I78 Diseases of capillaries
0.000 0.995 0.005
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.995 0.005
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.995 0.005
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.995 0.005
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.995 0.005
Z95.4 Presence of other heart-valve replacement
0.000 0.995 0.005
I70.9 Generalised and unspecified atherosclerosis
0.000 0.995 0.005
H65.3 Chronic mucoid otitis media
0.000 0.995 0.005
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.995 0.005
I77.6 Arteritis, unspecified
0.000 0.995 0.005
I70.8 Atherosclerosis of other arteries
0.000 0.995 0.005
I70.1 Atherosclerosis of renal artery
0.000 0.995 0.005
L72.0 Epidermal cyst
0.005 0.995 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.995 0.005
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.995 0.005
I72.9 Aneurysm of unspecified site
0.000 0.995 0.004
I44 Atrioventricular and left bundle-branch block
0.000 0.995 0.005
I72.1 Aneurysm of artery of upper extremity
0.000 0.995 0.004
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.995 0.004
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.995 0.004
I70.0 Atherosclerosis of aorta
0.000 0.995 0.004
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.995 0.004
I72.4 Aneurysm of artery of lower extremity
0.000 0.995 0.004
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.996 0.004
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.996 0.004
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.996 0.004
I72.2 Aneurysm of renal artery
0.000 0.996 0.004
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.004 0.996 0.000
I72.8 Aneurysm of other specified arteries
0.000 0.996 0.004
I44.6 Other and unspecified fascicular block
0.000 0.996 0.004
I72.0 Aneurysm of carotid artery
0.000 0.996 0.004
I74.8 Embolism and thrombosis of other arteries
0.000 0.996 0.004
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.996 0.004
I73 Other peripheral vascular diseases
0.000 0.996 0.004
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.996 0.004
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.996 0.004
I72.3 Aneurysm of iliac artery
0.000 0.996 0.004
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.996 0.004
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.996 0.004
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.996 0.004
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.996 0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.996 0.004
I78.9 Disease of capillaries, unspecified
0.000 0.996 0.004
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.996 0.004
I78.8 Other diseases of capillaries
0.000 0.996 0.004
T43.6 Psychostimulants with abuse potential
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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