TreeWAS – Variant ID: rs2149954

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.000	1.000
I10-I15 Hypertensive diseases	0.000	0.544	0.456
I11 Hypertensive heart disease	0.000	0.637	0.363
I08 Multiple valve diseases	0.000	0.662	0.338
I05-I09 Chronic rheumatic heart diseases	0.000	0.670	0.330
I08.0 Disorders of both mitral and aortic valves	0.000	0.676	0.324
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.678	0.322
Chapter IX Diseases of the circulatory system	0.000	0.686	0.314
I05 Rheumatic mitral valve diseases	0.000	0.693	0.307
I15 Secondary hypertension	0.000	0.694	0.306
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.697	0.303
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.700	0.300
I20-I25 Ischaemic heart diseases	0.000	0.713	0.287
I05.2 Mitral stenosis with insufficiency	0.000	0.713	0.287
I25 Chronic ischaemic heart disease	0.000	0.718	0.282
I08.8 Other multiple valve diseases	0.000	0.721	0.279
I13 Hypertensive heart and renal disease	0.000	0.730	0.269
I25.1 Atherosclerotic heart disease	0.000	0.741	0.259
I20.8 Other forms of angina pectoris	0.000	0.743	0.257
I20 Angina pectoris	0.000	0.745	0.255
I15.9 Seconday hypertension, unspecified	0.000	0.748	0.252
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.752	0.248
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.753	0.247
I09 Other rheumatic heart diseases	0.000	0.755	0.245
I08.9 Multiple valve disease, unspecified	0.000	0.759	0.241
I05.9 Mitral valve disease, unspecified	0.000	0.763	0.237
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.763	0.237
I60-I69 Cerebrovascular diseases	0.000	0.764	0.236
I60 Subarachnoid haemorrhage	0.000	0.767	0.233
I05.0 Mitral stenosis	0.000	0.770	0.230
I06 Rheumatic aortic valve diseases	0.000	0.772	0.228
I25.5 Ischaemic cardiomyopathy	0.000	0.773	0.227
I25.2 Old myocardial infarction	0.000	0.774	0.226
I62 Other nontraumatic intracranial haemorrhage	0.000	0.777	0.223
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.777	0.223
I05.8 Other mitral valve diseases	0.000	0.779	0.220
I15.8 Other secondary hypertension	0.000	0.780	0.219
I00-I02 Acute rheumatic fever	0.000	0.787	0.213
I05.1 Rheumatic mitral insufficiency	0.000	0.789	0.211
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.793	0.207
I25.3 Aneurysm of heart	0.000	0.794	0.206
I15.2 Hypertension secondary to endocrine disorders	0.000	0.795	0.205
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.796	0.204
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.797	0.203
I25.6 Silent myocardial ischaemia	0.000	0.798	0.202
I15.0 Renovascular hypertension	0.000	0.803	0.197
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.806	0.193
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.806	0.193
I25.4 Coronary artery aneurysm	0.000	0.808	0.192
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.809	0.191
I15.1 Hypertension secondary to other renal disorders	0.000	0.811	0.189
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.811	0.189
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.815	0.185
I23 Certain current complications following acute myocardial infarction	0.000	0.815	0.184
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.816	0.184
I09.9 Rheumatic heart disease, unspecified	0.000	0.816	0.184
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.820	0.180
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.820	0.180
I09.8 Other specified rheumatic heart diseases	0.000	0.824	0.175
I09.2 Chronic rheumatic pericarditis	0.000	0.824	0.175
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.824	0.175
I09.0 Rheumatic myocarditis	0.000	0.824	0.175
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.826	0.174
I22 Subsequent myocardial infarction	0.000	0.827	0.173
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.828	0.172
I62.1 Nontraumatic extradural haemorrhage	0.000	0.828	0.172
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.830	0.170
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.832	0.168
I07 Rheumatic tricuspid valve diseases	0.000	0.832	0.167
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.833	0.167
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.833	0.167
I12 Hypertensive renal disease	0.000	0.833	0.167
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.837	0.163
I06.8 Other rheumatic aortic valve diseases	0.000	0.837	0.163
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.837	0.163
I95.1 Orthostatic hypotension	0.000	0.837	0.163
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.839	0.161
I06.0 Rheumatic aortic stenosis	0.000	0.839	0.160
I95 Hypotension	0.000	0.840	0.160
I06.1 Rheumatic aortic insufficiency	0.000	0.842	0.157
I02 Rheumatic chorea	0.000	0.847	0.153
I01 Rheumatic fever with heart involvement	0.000	0.847	0.153
I61 Intracerebral haemorrhage	0.000	0.851	0.149
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.852	0.148
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.853	0.147
I68.0 Cerebral amyloid angiopathy	0.000	0.854	0.146
I24 Other acute ischaemic heart diseases	0.000	0.856	0.144
I00 Rheumatic fever without mention of heart involvement	0.000	0.860	0.140
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.867	0.133
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.867	0.132
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.867	0.132
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.867	0.132
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.867	0.132
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.867	0.132
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.867	0.132
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.867	0.132
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.868	0.132
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.868	0.132
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.868	0.132
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.871	0.129
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.871	0.129
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.871	0.129
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.874	0.125
I95.0 Idiopathic hypotension	0.000	0.877	0.123
I07.9 Tricuspid valve disease, unspecified	0.000	0.880	0.120
I07.8 Other tricuspid valve diseases	0.000	0.880	0.120
I07.2 Tricuspid stenosis with insufficiency	0.000	0.880	0.120
I07.0 Tricuspid stenosis	0.000	0.880	0.120
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.883	0.117
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.884	0.116
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.884	0.116
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.884	0.116
I95.8 Other hypotension	0.000	0.885	0.115
I20.1 Angina pectoris with documented spasm	0.000	0.886	0.114
I23.8 Other current complications following acute myocardial infarction	0.000	0.889	0.111
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.890	0.110
I01.8 Other acute rheumatic heart disease	0.000	0.890	0.110
I01.2 Acute rheumatic myocarditis	0.000	0.890	0.110
I01.1 Acute rheumatic endocarditis	0.000	0.890	0.110
I01.0 Acute rheumatic pericarditis	0.000	0.890	0.110
I02.9 Rheumatic chorea without heart involvement	0.000	0.890	0.110
I02.0 Rheumatic chorea with heart involvement	0.000	0.890	0.110
I22.8 Subsequent myocardial infarction of other sites	0.000	0.890	0.110
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.890	0.109
I21 Acute myocardial infarction	0.000	0.892	0.108
I24.1 Dressler's syndrome	0.000	0.893	0.107
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.894	0.106
I28 Other diseases of pulmonary vessels	0.000	0.896	0.104
I60.8 Other subarachnoid haemorrhage	0.000	0.898	0.102
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.899	0.101
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.899	0.101
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.899	0.101
I24.8 Other forms of acute ischaemic heart disease	0.000	0.900	0.100
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.900	0.100
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.900	0.100
I20.9 Angina pectoris, unspecified	0.000	0.904	0.096
I20.0 Unstable angina	0.000	0.904	0.096
I99 Other and unspecified disorders of circulatory system	0.000	0.905	0.095
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.909	0.091
I61.8 Other intracerebral haemorrhage	0.000	0.909	0.091
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.911	0.089
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.912	0.087
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.913	0.087
I28.8 Other specified diseases of pulmonary vessels	0.000	0.913	0.087
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.915	0.085
Z95.1 Presence of aortocoronary bypass graft	0.000	0.919	0.081
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.920	0.080
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.921	0.079
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.922	0.078
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.922	0.077
E78.0 Pure hypercholesterolaemia	0.000	0.923	0.077
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.924	0.076
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.925	0.075
I28.1 Aneurysm of pulmonary artery	0.000	0.925	0.075
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.925	0.075
I12.0 Hypertensive renal disease with renal failure	0.000	0.925	0.075
I98 Other disorders of circulatory system in diseases classified elsewhere	0.001	0.925	0.074
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.928	0.072
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.929	0.071
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.931	0.068
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.933	0.067
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.935	0.065
Z95.4 Presence of other heart-valve replacement	0.000	0.936	0.064
I26 Pulmonary embolism	0.000	0.937	0.063
I12.9 Hypertensive renal disease without renal failure	0.000	0.940	0.060
I95.2 Hypotension due to drugs	0.000	0.942	0.058
I65.1 Occlusion and stenosis of basilar artery	0.000	0.943	0.057
Z95.2 Presence of prosthetic heart valve	0.000	0.945	0.055
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.945	0.055
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.945	0.054
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.945	0.054
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.001	0.946	0.054
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.001	0.946	0.054
I98.0 Cardiovascular syphilis	0.001	0.946	0.054
I63 Cerebral infarction	0.000	0.946	0.054
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.947	0.053
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.949	0.051
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.949	0.051
I07.1 Tricuspid insufficiency	0.000	0.949	0.051
Z95.3 Presence of xenogenic heart valve	0.000	0.949	0.051
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.950	0.050
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.951	0.049
I97.1 Other functional disturbances following cardiac surgery	0.000	0.953	0.047
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.955	0.044
I97.0 Postcardiotomy syndrome	0.000	0.956	0.043
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.958	0.041
I51.8 Other ill-defined heart diseases	0.000	0.960	0.040
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.961	0.039
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.961	0.039
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.961	0.039
I51 Complications and ill-defined descriptions of heart disease	0.000	0.961	0.039
I30-I52 Other forms of heart disease	0.000	0.961	0.039
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.962	0.037
Z82.3 Family history of stroke	0.000	0.962	0.038
I33 Acute and subacute endocarditis	0.000	0.963	0.037
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.963	0.037
I51.6 Cardiovascular disease, unspecified	0.000	0.964	0.036
I33.0 Acute and subacute infective endocarditis	0.000	0.964	0.036
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.964	0.036
I42 Cardiomyopathy	0.000	0.966	0.034
I42.2 Other hypertrophic cardiomyopathy	0.000	0.966	0.034
I21.4 Acute subendocardial myocardial infarction	0.000	0.966	0.034
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.966	0.034
I51.0 Cardiac septal defect, acquired	0.000	0.968	0.032
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.969	0.031
I42.8 Other cardiomyopathies	0.000	0.970	0.030
Z82.1 Family history of blindness and visual loss	0.000	0.970	0.030
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.971	0.029
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.971	0.029
I69 Sequelae of cerebrovascular disease	0.000	0.971	0.029
I33.9 Acute endocarditis, unspecified	0.000	0.971	0.028
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.972	0.028
I35.1 Aortic (valve) insufficiency	0.000	0.972	0.028
I50 Heart failure	0.000	0.972	0.028
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.972	0.028
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.972	0.028
I52 Other heart disorders in diseases classified elsewhere	0.000	0.972	0.028
I48 Atrial fibrillation and flutter	0.000	0.972	0.028
I41 Myocarditis in diseases classified elsewhere	0.000	0.972	0.028
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.972	0.028
I32 Pericarditis in diseases classified elsewhere	0.000	0.972	0.028
I35 Nonrheumatic aortic valve disorders	0.000	0.972	0.028
I67 Other cerebrovascular diseases	0.000	0.972	0.028
I36 Nonrheumatic tricuspid valve disorders	0.000	0.972	0.027
I34 Nonrheumatic mitral valve disorders	0.000	0.972	0.028
I50.0 Congestive heart failure	0.000	0.973	0.027
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.973	0.027
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.973	0.027
I51.9 Heart disease, unspecified	0.000	0.973	0.027
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.974	0.026
I51.5 Myocardial degeneration	0.000	0.975	0.025
I40 Acute myocarditis	0.000	0.975	0.025
I42.5 Other restrictive cardiomyopathy	0.000	0.975	0.025
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.975	0.025
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.975	0.024
I51.4 Myocarditis, unspecified	0.000	0.976	0.024
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.976	0.024
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.976	0.024
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.976	0.024
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.976	0.024
I37 Pulmonary valve disorders	0.000	0.977	0.023
I42.4 Endocardial fibroelastosis	0.000	0.978	0.022
I38 Endocarditis, valve unspecified	0.000	0.978	0.022
I63.8 Other cerebral infarction	0.000	0.978	0.021
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.979	0.021
I42.6 Alcoholic cardiomyopathy	0.000	0.979	0.021
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.979	0.021
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.979	0.021
I35.9 Aortic valve disorder, unspecified	0.000	0.979	0.021
I34.1 Mitral (valve) prolapse	0.000	0.979	0.021
Z82.2 Family history of deafness and hearing loss	0.000	0.980	0.020
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.980	0.020
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.980	0.020
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.980	0.020
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.980	0.020
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.980	0.020
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.980	0.020
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.980	0.020
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.980	0.020
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.980	0.020
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.980	0.020
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.980	0.020
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.980	0.020
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.980	0.020
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.980	0.020
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.980	0.020
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.980	0.020
I48.4 Atypical atrial flutter	0.000	0.980	0.020
I48.3 Typical atrial flutter	0.000	0.980	0.020
I48.2 Chronic atrial fibrillation	0.000	0.980	0.020
I48.1 Persistent atrial fibrillation	0.000	0.980	0.020
I48.0 Paroxysmal atrial fibrillation	0.000	0.980	0.020
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.980	0.020
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.980	0.020
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.980	0.020
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.980	0.020
I27 Other pulmonary heart diseases	0.000	0.980	0.020
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.980	0.020
I67.5 Moyamoya disease	0.000	0.980	0.020
I67.4 Hypertensive encephalopathy	0.000	0.980	0.020
I67.3 Progressive vascular leukoencephalopathy	0.000	0.980	0.020
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.980	0.020
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.980	0.020
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.980	0.020
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.980	0.020
I49 Other cardiac arrhythmias	0.000	0.980	0.020
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.980	0.019
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.981	0.019
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.981	0.019
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.981	0.019
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.981	0.018
I40.8 Other acute myocarditis	0.000	0.982	0.018
I40.1 Isolated myocarditis	0.000	0.982	0.018
I49.1 Atrial premature depolarisation	0.000	0.982	0.018
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.983	0.017
I67.2 Cerebral atherosclerosis	0.000	0.983	0.017
I21.9 Acute myocardial infarction, unspecified	0.000	0.983	0.017
I40.9 Acute myocarditis, unspecified	0.000	0.983	0.017
I40.0 Infective myocarditis	0.000	0.983	0.017
I37.9 Pulmonary valve disorder, unspecified	0.000	0.983	0.017
I37.8 Other pulmonary valve disorders	0.000	0.983	0.017
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.983	0.017
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.000	0.983	0.017
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.983	0.016
I45 Other conduction disorders	0.000	0.983	0.017
I37.0 Pulmonary valve stenosis	0.000	0.984	0.016
I49.0 Ventricular fibrillation and flutter	0.000	0.984	0.016
I63.9 Cerebral infarction, unspecified	0.000	0.984	0.016
I30 Acute pericarditis	0.000	0.985	0.015
I27.1 Kyphoscoliotic heart disease	0.000	0.985	0.014
I49.2 Junctional premature depolarisation	0.000	0.986	0.014
I27.9 Pulmonary heart disease, unspecified	0.000	0.986	0.014
I49.8 Other specified cardiac arrhythmias	0.000	0.986	0.014
I45.2 Bifascicular block	0.000	0.986	0.014
I45.8 Other specified conduction disorders	0.000	0.986	0.014
I45.5 Other specified heart block	0.000	0.986	0.014
I49.5 Sick sinus syndrome	0.000	0.986	0.014
I49.4 Other and unspecified premature depolarisation	0.000	0.987	0.013
I67.8 Other specified cerebrovascular diseases	0.000	0.987	0.013
I35.0 Aortic (valve) stenosis	0.000	0.987	0.013
I50.1 Left ventricular failure	0.000	0.987	0.013
I45.4 Nonspecific intraventricular block	0.000	0.987	0.013
I37.1 Pulmonary valve insufficiency	0.000	0.987	0.013
I50.9 Heart failure, unspecified	0.000	0.988	0.012
I45.0 Right fascicular block	0.000	0.988	0.012
I98.2 Oesophageal varices in diseases classified elsewhere	0.001	0.988	0.011
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.988	0.012
I27.8 Other specified pulmonary heart diseases	0.000	0.988	0.012
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.988	0.011
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.989	0.011
I30.8 Other forms of acute pericarditis	0.000	0.989	0.011
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.989	0.011
T39.1 4-Aminophenol derivatives	0.000	0.989	0.011
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.990	0.010
I35.8 Other aortic valve disorders	0.000	0.990	0.010
I34.0 Mitral (valve) insufficiency	0.000	0.990	0.010
I45.9 Conduction disorder, unspecified	0.000	0.990	0.010
T39.0 Salicylates	0.000	0.990	0.010
Z95.0 Presence of cardiac pacemaker	0.000	0.991	0.009
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.001	0.991	0.008
I30.1 Infective pericarditis	0.000	0.991	0.008
I45.3 Trifascicular block	0.000	0.991	0.008
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.991	0.009
R47.0 Dysphasia and aphasia	0.000	0.991	0.009
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.992	0.008
I31 Other diseases of pericardium	0.000	0.992	0.008
I46 Cardiac arrest	0.001	0.992	0.008
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.992	0.008
C67.6 Ureteric orifice	0.008	0.992	0.000
I47 Paroxysmal tachycardia	0.000	0.992	0.008
I77 Other disorders of arteries and arterioles	0.000	0.992	0.008
I69.3 Sequelae of cerebral infarction	0.000	0.992	0.007
I49.3 Ventricular premature depolarisation	0.000	0.992	0.008
C67.2 Lateral wall of bladder	0.008	0.992	0.000
C67.4 Posterior wall of bladder	0.008	0.992	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.008	0.992	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.992	0.008
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.992	0.008
C67 Malignant neoplasm of bladder	0.007	0.993	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.993	0.007
O41.0 Oligohydramnios	0.007	0.993	0.000
I31.0 Chronic adhesive pericarditis	0.000	0.993	0.007
I77.8 Other specified disorders of arteries and arterioles	0.000	0.993	0.007
C67.0 Trigone of bladder	0.007	0.993	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.993	0.006
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.993	0.006
I47.0 Reentry ventricular arrhythmia	0.000	0.993	0.006
O41 Other disorders of amniotic fluid and membranes	0.006	0.994	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.994	0.006
I79.1 Aortitis in diseases classified elsewhere	0.000	0.994	0.006
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.994	0.006
I73 Other peripheral vascular diseases	0.000	0.994	0.006
I42.9 Cardiomyopathy, unspecified	0.000	0.994	0.006
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.994	0.006
C67.3 Anterior wall of bladder	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.994	0.006
T39.2 Pyrazolone derivatives	0.000	0.994	0.006
I31.8 Other specified diseases of pericardium	0.000	0.994	0.006
I31.2 Haemopericardium, not elsewhere classified	0.000	0.994	0.006
I46.1 Sudden cardiac death, so described	0.001	0.994	0.006
I77.2 Rupture of artery	0.000	0.994	0.006
I65.2 Occlusion and stenosis of carotid artery	0.000	0.994	0.006
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.001	0.994	0.005
I77.5 Necrosis of artery	0.000	0.994	0.006
I77.4 Coeliac artery compression syndrome	0.000	0.994	0.006
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.994	0.006
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.994	0.006
I77.6 Arteritis, unspecified	0.000	0.994	0.006
I73.0 Raynaud's syndrome	0.000	0.994	0.006
I77.3 Arterial fibromuscular dysplasia	0.000	0.994	0.006
Q05.9 Spina bifida, unspecified	0.006	0.994	0.000
I42.0 Dilated cardiomyopathy	0.000	0.994	0.006
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.994	0.006
Z57.2 Occupational exposure to dust	0.006	0.994	0.000
C67.7 Urachus	0.005	0.994	0.000
L81.4 Other melanin hyperpigmentation	0.006	0.994	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.995	0.005
K14.8 Other diseases of tongue	0.005	0.995	0.000
I72 Other aneurysm	0.000	0.995	0.005
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.995	0.005
I70 Atherosclerosis	0.000	0.995	0.005
Q05 Spina bifida	0.005	0.995	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.995	0.005
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.005	0.995	0.000
C67.5 Bladder neck	0.005	0.995	0.000
I47.2 Ventricular tachycardia	0.000	0.995	0.005
R09.1 Pleurisy	0.005	0.995	0.000
I31.1 Chronic constrictive pericarditis	0.000	0.995	0.005
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.995	0.005
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.995	0.005
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.995	0.005
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.995	0.005
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.995	0.005
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.995	0.005
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.995	0.005
C67.8 Overlapping lesion of bladder	0.005	0.995	0.000
I72.2 Aneurysm of renal artery	0.000	0.995	0.005
O41.1 Infection of amniotic sac and membranes	0.005	0.995	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.995	0.005
I78 Diseases of capillaries	0.000	0.995	0.005
I77.0 Arteriovenous fistula, acquired	0.000	0.995	0.004
I45.6 Preexcitation syndrome	0.000	0.995	0.004
I30.9 Acute pericarditis, unspecified	0.001	0.995	0.004
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.996	0.004
I45.1 Other and unspecified right bundle-branch block	0.000	0.996	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
Q05.4 Unspecified spina bifida with hydrocephalus	0.004	0.996	0.000
I72.0 Aneurysm of carotid artery	0.000	0.996	0.004
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.996	0.004
I71 Aortic aneurysm and dissection	0.000	0.996	0.004
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.996	0.004
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.996	0.004
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.996	0.004
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.996	0.004
I72.4 Aneurysm of artery of lower extremity	0.000	0.996	0.004
K01.1 Impacted teeth	0.000	0.996	0.004
I72.1 Aneurysm of artery of upper extremity	0.000	0.996	0.004
I70.8 Atherosclerosis of other arteries	0.000	0.996	0.004
D86 Sarcoidosis	0.004	0.996	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.004	0.996	0.000
M21.26 Flexion deformity (Lower leg)	0.004	0.996	0.000
I95.9 Hypotension, unspecified	0.000	0.996	0.004
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.996	0.004
I27.2 Other secondary pulmonary hypertension	0.000	0.996	0.004
M46 Other inflammatory spondylopathies	0.000	0.996	0.004
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.996	0.004
I70.9 Generalised and unspecified atherosclerosis	0.000	0.996	0.004
Q03 Congenital hydrocephalus	0.004	0.996	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.996	0.004
M21.2 Flexion deformity	0.004	0.996	0.000
K74.6 Other and unspecified cirrhosis of liver	0.004	0.996	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.996	0.004
I44 Atrioventricular and left bundle-branch block	0.000	0.996	0.004
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.000	0.996	0.004
K26.7 Chronic without haemorrhage or perforation	0.000	0.996	0.004
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.996	0.004
Q04 Other congenital malformations of brain	0.004	0.996	0.000
Z57 Occupational exposure to risk-factors	0.004	0.996	0.000
I27.0 Primary pulmonary hypertension	0.000	0.996	0.003
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
M21.0 Valgus deformity, not elsewhere classified	0.004	0.996	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.996	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.003	0.996	0.000
C67.1 Dome of bladder	0.003	0.996	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.996	0.004
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.996	0.003
I72.9 Aneurysm of unspecified site	0.000	0.996	0.003
Q06 Other congenital malformations of spinal cord	0.003	0.996	0.000
I78.8 Other diseases of capillaries	0.000	0.997	0.003
M21 Other acquired deformities of limbs	0.003	0.997	0.000
I70.0 Atherosclerosis of aorta	0.000	0.997	0.003
M21.4 Flat foot [pes planus] (acquired)	0.003	0.997	0.000
S29.9 Unspecified injury of thorax	0.003	0.997	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.997	0.003
Z57.5 Occupational exposure to toxic agents in other industries	0.003	0.997	0.000
B02.3 Zoster ocular disease	0.000	0.997	0.003
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.997	0.003
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.997	0.003
M46.0 Spinal enthesopathy	0.000	0.997	0.003
I74 Arterial embolism and thrombosis	0.000	0.997	0.003
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.997	0.003
Q04.6 Congenital cerebral cysts	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.997	0.003
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations