TreeWAS – Variant ID: rs2151280

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.9 Glaucoma, unspecified	1.000	0.000	0.000
H40.1 Primary open-angle glaucoma	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I21.9 Acute myocardial infarction, unspecified	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
I25.2 Old myocardial infarction	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
C44.5 Skin of trunk	0.000	0.000	1.000
C71 Malignant neoplasm of brain	0.000	0.000	1.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000	0.000
I20.0 Unstable angina	1.000	0.000	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	1.000	0.000	0.000
I22 Subsequent myocardial infarction	1.000	0.000	0.000
I21.4 Acute subendocardial myocardial infarction	1.000	0.000	0.000
H40 Glaucoma	1.000	0.000	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.000	1.000
C71.9 Brain, unspecified	0.000	0.001	0.999
C44.0 Skin of lip	0.000	0.001	0.999
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.002	0.998
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.002	0.998
I21.1 Acute transmural myocardial infarction of inferior wall	0.997	0.003	0.000
Chapter II Neoplasms	0.000	0.003	0.997
C44.1 Skin of eyelid, including canthus	0.000	0.003	0.997
I73.9 Peripheral vascular disease, unspecified	0.996	0.004	0.000
I73 Other peripheral vascular diseases	0.995	0.005	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.995	0.005	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.006	0.994
D00-D09 In situ neoplasms	0.000	0.007	0.993
C71.1 Frontal lobe	0.000	0.007	0.993
C44.4 Skin of scalp and neck	0.000	0.008	0.992
D05 Carcinoma in situ of breast	0.000	0.008	0.992
C15 Malignant neoplasm of oesophagus	0.000	0.008	0.992
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.010	0.990
I22.9 Subsequent myocardial infarction of unspecified site	0.988	0.012	0.000
I72 Other aneurysm	0.983	0.017	0.000
I24 Other acute ischaemic heart diseases	0.981	0.019	0.000
C15.5 Lower third of oesophagus	0.000	0.020	0.980
I21.0 Acute transmural myocardial infarction of anterior wall	0.977	0.023	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.975	0.025	0.000
C15.9 Oesophagus, unspecified	0.000	0.032	0.968
I22.1 Subsequent myocardial infarction of inferior wall	0.967	0.033	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.960	0.040	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.041	0.959
C71.2 Temporal lobe	0.000	0.041	0.959
Z82.3 Family history of stroke	0.951	0.049	0.000
I74 Arterial embolism and thrombosis	0.949	0.051	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.949	0.051	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.947	0.053	0.000
C21 Malignant neoplasm of anus and anal canal	0.000	0.053	0.947
I22.0 Subsequent myocardial infarction of anterior wall	0.947	0.053	0.000
I77 Other disorders of arteries and arterioles	0.944	0.056	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.941	0.059	0.000
I20.8 Other forms of angina pectoris	0.939	0.061	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.064	0.936
I77.1 Stricture of artery	0.936	0.064	0.000
C71.8 Overlapping lesion of brain	0.000	0.082	0.918
I70 Atherosclerosis	0.915	0.085	0.000
I25.5 Ischaemic cardiomyopathy	0.914	0.086	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.092	0.908
I24.8 Other forms of acute ischaemic heart disease	0.908	0.092	0.000
C71.3 Parietal lobe	0.000	0.094	0.906
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.095	0.905
Z92.2 Personal history of long-term (current) use of other medicaments	0.905	0.095	0.000
C17 Malignant neoplasm of small intestine	0.000	0.108	0.892
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.112	0.888
I72.3 Aneurysm of iliac artery	0.877	0.122	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.123	0.877
H40.0 Glaucoma suspect	0.870	0.130	0.000
I25.4 Coronary artery aneurysm	0.870	0.130	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.133	0.867
C71.0 Cerebrum, except lobes and ventricles	0.000	0.134	0.866
C20 Malignant neoplasm of rectum	0.000	0.145	0.855
I25.3 Aneurysm of heart	0.844	0.156	0.000
I72.0 Aneurysm of carotid artery	0.843	0.157	0.000
D02.0 Larynx	0.000	0.159	0.841
I70.2 Atherosclerosis of arteries of the extremities	0.840	0.160	0.000
I22.8 Subsequent myocardial infarction of other sites	0.838	0.162	0.000
C16 Malignant neoplasm of stomach	0.000	0.165	0.835
C02.9 Tongue, unspecified	0.000	0.172	0.828
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.179	0.821
C21.0 Anus, unspecified	0.000	0.181	0.818
I72.1 Aneurysm of artery of upper extremity	0.813	0.187	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.190	0.810
I72.4 Aneurysm of artery of lower extremity	0.804	0.196	0.000
C16.0 Cardia	0.000	0.196	0.804
I72.9 Aneurysm of unspecified site	0.802	0.197	0.000
I70.1 Atherosclerosis of renal artery	0.799	0.201	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.797	0.203	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.208	0.792
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.208	0.792
D05.0 Lobular carcinoma in situ	0.000	0.220	0.780
I73.8 Other specified peripheral vascular diseases	0.770	0.230	0.000
C32 Malignant neoplasm of larynx	0.000	0.232	0.768
C17.0 Duodenum	0.000	0.232	0.768
I72.8 Aneurysm of other specified arteries	0.767	0.233	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.766	0.234	0.000
Z95.3 Presence of xenogenic heart valve	0.763	0.237	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.000	0.238	0.762
I77.0 Arteriovenous fistula, acquired	0.762	0.238	0.000
Chapter IX Diseases of the circulatory system	0.760	0.240	0.000
I72.2 Aneurysm of renal artery	0.752	0.247	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.749	0.251	0.000
I74.8 Embolism and thrombosis of other arteries	0.738	0.262	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.262	0.738
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.737	0.263	0.000
I25.6 Silent myocardial ischaemia	0.727	0.273	0.000
C23 Malignant neoplasm of gallbladder	0.000	0.274	0.726
C15.0 Cervical part of oesophagus	0.000	0.274	0.726
C00 Malignant neoplasm of lip	0.000	0.277	0.723
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.721	0.279	0.000
C44.8 Overlapping lesion of skin	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
C71.5 Cerebral ventricle	0.000	0.283	0.717
H40.6 Glaucoma secondary to drugs	0.717	0.283	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.284	0.716
I70.10 Atherosclerosis of renal artery (without gangrene)	0.716	0.284	0.000
C02.4 Lingual tonsil	0.000	0.285	0.715
C71.7 Brain stem	0.000	0.287	0.713
C15.8 Overlapping lesion of oesophagus	0.000	0.289	0.711
C15.2 Abdominal part of oesophagus	0.000	0.289	0.711
C08.9 Major salivary gland, unspecified	0.000	0.289	0.711
C21.1 Anal canal	0.000	0.289	0.711
C07 Malignant neoplasm of parotid gland	0.000	0.290	0.710
I77.3 Arterial fibromuscular dysplasia	0.709	0.291	0.000
H40.3 Glaucoma secondary to eye trauma	0.707	0.293	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.705	0.295	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.705	0.295	0.000
C17.9 Small intestine, unspecified	0.000	0.296	0.704
I77.9 Disorder of arteries and arterioles, unspecified	0.704	0.296	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.298	0.701
C32.9 Larynx, unspecified	0.000	0.306	0.694
C71.6 Cerebellum	0.000	0.307	0.693
I74.9 Embolism and thrombosis of unspecified artery	0.686	0.314	0.000
I70.8 Atherosclerosis of other arteries	0.683	0.317	0.000
C04 Malignant neoplasm of floor of mouth	0.000	0.321	0.679
C21.2 Cloacogenic zone	0.000	0.321	0.679
C17.1 Jejunum	0.000	0.321	0.679
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.678	0.322	0.000
I77.5 Necrosis of artery	0.677	0.323	0.000
I77.4 Coeliac artery compression syndrome	0.677	0.323	0.000
C32.0 Glottis	0.000	0.326	0.674
I74.0 Embolism and thrombosis of abdominal aorta	0.673	0.327	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.672	0.328	0.000
C10 Malignant neoplasm of oropharynx	0.000	0.328	0.672
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.668	0.332	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.332	0.667
C02.1 Border of tongue	0.000	0.335	0.665
H40.2 Primary angle-closure glaucoma	0.660	0.340	0.000
C16.5 Lesser curvature of stomach, unspecified	0.000	0.341	0.659
C05 Malignant neoplasm of palate	0.000	0.342	0.658
C15.3 Upper third of oesophagus	0.000	0.343	0.657
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.657	0.343	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.343	0.656
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.344	0.656
C17.2 Ileum	0.000	0.347	0.653
C15.1 Thoracic part of oesophagus	0.000	0.348	0.652
I25.0 Atherosclerotic cardiovascular disease, so described	0.651	0.349	0.000
D02.4 Respiratory system, unspecified	0.000	0.351	0.649
D02.3 Other parts of respiratory system	0.000	0.351	0.649
D02.2 Bronchus and lung	0.000	0.351	0.649
D02.1 Trachea	0.000	0.351	0.649
C02.2 Ventral surface of tongue	0.000	0.353	0.647
Z82.1 Family history of blindness and visual loss	0.646	0.354	0.000
C08.0 Submandibular gland	0.000	0.355	0.645
H40.8 Other glaucoma	0.645	0.355	0.000
D04 Carcinoma in situ of skin	0.000	0.357	0.643
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.642	0.358	0.000
D01.2 Rectum	0.000	0.360	0.640
C17.8 Overlapping lesion of small intestine	0.000	0.361	0.639
C17.3 Meckel's diverticulum	0.000	0.361	0.639
C13 Malignant neoplasm of hypopharynx	0.000	0.361	0.639
C02.8 Overlapping lesion of tongue	0.000	0.363	0.636
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.363	0.636
C02.0 Dorsal surface of tongue	0.000	0.363	0.636
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.374	0.626
I70.9 Generalised and unspecified atherosclerosis	0.625	0.375	0.000
D07.2 Vagina	0.000	0.377	0.623
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.615	0.385	0.000
H40.4 Glaucoma secondary to eye inflammation	0.615	0.385	0.000
C31 Malignant neoplasm of accessory sinuses	0.000	0.387	0.613
D07.1 Vulva	0.000	0.387	0.613
Z82.2 Family history of deafness and hearing loss	0.612	0.387	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.388	0.612
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.388	0.611
I23 Certain current complications following acute myocardial infarction	0.610	0.390	0.000
C70 Malignant neoplasm of meninges	0.000	0.392	0.608
I24.1 Dressler's syndrome	0.607	0.393	0.000
C12 Malignant neoplasm of pyriform sinus	0.000	0.393	0.607
C11 Malignant neoplasm of nasopharynx	0.000	0.394	0.606
C71.4 Occipital lobe	0.000	0.397	0.603
C16.1 Fundus of stomach	0.000	0.401	0.599
C03 Malignant neoplasm of gum	0.000	0.402	0.598
I73.0 Raynaud's syndrome	0.595	0.405	0.000
C14.0 Pharynx, unspecified	0.000	0.405	0.595
C16.8 Overlapping lesion of stomach	0.000	0.405	0.595
D01.0 Colon	0.000	0.405	0.595
C37 Malignant neoplasm of thymus	0.000	0.407	0.593
C08.8 Overlapping lesion of major salivary glands	0.000	0.412	0.588
C08.1 Sublingual gland	0.000	0.412	0.588
D07.5 Prostate	0.000	0.414	0.586
C16.6 Greater curvature of stomach, unspecified	0.000	0.416	0.584
D05.1 Intraductal carcinoma in situ	0.000	0.419	0.581
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.581	0.419	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.419	0.580
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.000	0.425	0.575
I70.11 Atherosclerosis of renal artery (with gangrene)	0.573	0.427	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.430	0.570
D01.9 Digestive organ, unspecified	0.000	0.432	0.568
D01.7 Other specified digestive organs	0.000	0.432	0.568
D01.5 Liver, gallbladder and bile ducts	0.000	0.432	0.568
D01.4 Other and unspecified parts of intestine	0.000	0.432	0.568
D01.1 Rectosigmoid junction	0.000	0.432	0.568
D07.6 Other and unspecified male genital organs	0.000	0.432	0.568
D07.3 Other and unspecified female genital organs	0.000	0.432	0.568
D07.0 Endometrium	0.000	0.432	0.568
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.000	0.433	0.567
C32.1 Supraglottis	0.000	0.436	0.564
D04.2 Skin of ear and external auricular canal	0.000	0.437	0.563
D09 Carcinoma in situ of other and unspecified sites	0.000	0.437	0.563
C00.0 External upper lip	0.000	0.440	0.560
Z95.0 Presence of cardiac pacemaker	0.560	0.440	0.000
C16.4 Pylorus	0.000	0.442	0.558
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.443	0.557
C00.1 External lower lip	0.000	0.446	0.554
I77.2 Rupture of artery	0.554	0.446	0.000
D01.3 Anus and anal canal	0.000	0.448	0.552
C32.8 Overlapping lesion of larynx	0.000	0.449	0.550
C32.3 Laryngeal cartilage	0.000	0.449	0.550
C32.2 Subglottis	0.000	0.449	0.550
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.000	0.454	0.546
I74.5 Embolism and thrombosis of iliac artery	0.538	0.462	0.000
I00-I02 Acute rheumatic fever	0.534	0.466	0.000
H40.5 Glaucoma secondary to other eye disorders	0.534	0.466	0.000
C04.9 Floor of mouth, unspecified	0.000	0.470	0.530
D07.4 Penis	0.000	0.470	0.530
C16.9 Stomach, unspecified	0.000	0.470	0.530
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.000	0.471	0.529
C14.2 Waldeyer's ring	0.000	0.471	0.529
C33 Malignant neoplasm of trachea	0.000	0.472	0.528
D04.9 Skin, unspecified	0.000	0.476	0.524
C15.4 Middle third of oesophagus	0.000	0.479	0.521
C00.8 Overlapping lesion of lip	0.000	0.481	0.519
C00.6 Commissure of lip	0.000	0.481	0.519
C00.5 Lip, unspecified, inner aspect	0.000	0.481	0.519
C00.4 Lower lip, inner aspect	0.000	0.481	0.519
C00.3 Upper lip, inner aspect	0.000	0.481	0.519
C00.2 External lip, unspecified	0.000	0.481	0.519
C69 Malignant neoplasm of eye and adnexa	0.000	0.483	0.517
I79.1 Aortitis in diseases classified elsewhere	0.517	0.483	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.517	0.483	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.516	0.484	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.515	0.485	0.000
C72.0 Spinal cord	0.000	0.485	0.515
C72.9 Central nervous system, unspecified	0.000	0.486	0.514
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.486	0.514
C72.5 Other and unspecified cranial nerves	0.000	0.486	0.514
C72.4 Acoustic nerve	0.000	0.486	0.514
C72.3 Optic nerve	0.000	0.486	0.514
C72.2 Olfactory nerve	0.000	0.486	0.514
C72.1 Cauda equina	0.000	0.486	0.514
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.487	0.513
C05.9 Palate, unspecified	0.000	0.494	0.506
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.497	0.503
C18 Malignant neoplasm of colon	0.000	0.498	0.502
C06.0 Cheek mucosa	0.000	0.501	0.499
D06 Carcinoma in situ of cervix uteri	0.000	0.503	0.497
C00.9 Lip, unspecified	0.000	0.508	0.492
C06.2 Retromolar area	0.000	0.510	0.490
I70.81 Atherosclerosis of other arteries (with gangrene)	0.489	0.510	0.000
C04.8 Overlapping lesion of floor of mouth	0.000	0.513	0.487
C04.1 Lateral floor of mouth	0.000	0.513	0.487
C10.9 Oropharynx, unspecified	0.000	0.518	0.482
C10.8 Overlapping lesion of oropharynx	0.000	0.518	0.482
C10.4 Branchial cleft	0.000	0.518	0.482
C10.3 Posterior wall of oropharynx	0.000	0.518	0.482
C10.2 Lateral wall of oropharynx	0.000	0.518	0.482
C10.1 Anterior surface of epiglottis	0.000	0.518	0.482
C10.0 Vallecula	0.000	0.518	0.482
C24.0 Extrahepatic bile duct	0.000	0.519	0.481
C24.8 Overlapping lesion of biliary tract	0.000	0.521	0.479
C24.9 Biliary tract, unspecified	0.000	0.526	0.474
C31.0 Maxillary sinus	0.000	0.528	0.472
C05.8 Overlapping lesion of palate	0.000	0.528	0.471
C05.2 Uvula	0.000	0.528	0.471
C13.0 Postcricoid region	0.000	0.529	0.471
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.000	0.529	0.471
C06.1 Vestibule of mouth	0.000	0.529	0.471
I70.0 Atherosclerosis of aorta	0.469	0.530	0.001
C30.0 Nasal cavity	0.000	0.530	0.470
C18.3 Hepatic flexure	0.000	0.530	0.470
Z95.2 Presence of prosthetic heart valve	0.469	0.531	0.000
C44.7 Skin of lower limb, including hip	0.000	0.533	0.467
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.535	0.465
D04.8 Skin of other sites	0.000	0.539	0.461
D04.0 Skin of lip	0.000	0.539	0.461
C50-C50 Malignant neoplasm of breast	0.000	0.542	0.458
C13.8 Overlapping lesion of hypopharynx	0.000	0.542	0.458
C13.2 Posterior wall of hypopharynx	0.000	0.542	0.458
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.000	0.542	0.458
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.448	0.552	0.000
C05.0 Hard palate	0.000	0.555	0.444
C05.1 Soft palate	0.000	0.556	0.443
C04.0 Anterior floor of mouth	0.000	0.558	0.442
C40.0 Scapula and long bones of upper limb	0.000	0.558	0.442
D04.6 Skin of upper limb, including shoulder	0.000	0.560	0.440
C41.9 Bone and articular cartilage, unspecified	0.000	0.560	0.440
C31.9 Accessory sinus, unspecified	0.000	0.560	0.439
C31.8 Overlapping lesion of accessory sinuses	0.000	0.560	0.439
C31.3 Sphenoidal sinus	0.000	0.560	0.439
C31.2 Frontal sinus	0.000	0.560	0.439
C31.1 Ethmoidal sinus	0.000	0.560	0.439
D00.2 Stomach	0.000	0.561	0.439
C09 Malignant neoplasm of tonsil	0.000	0.561	0.438
C30.1 Middle ear	0.000	0.561	0.438
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.437	0.563	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.437	0.563	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.437	0.563	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.437	0.563	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.437	0.563	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.437	0.563	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.437	0.563	0.000
C70.9 Meninges, unspecified	0.000	0.564	0.436
C70.1 Spinal meninges	0.000	0.564	0.436
I77.8 Other specified disorders of arteries and arterioles	0.436	0.564	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.436	0.564	0.000
C24.1 Ampulla of Vater	0.000	0.564	0.436
C11.8 Overlapping lesion of nasopharynx	0.000	0.565	0.435
C11.3 Anterior wall of nasopharynx	0.000	0.565	0.435
C11.2 Lateral wall of nasopharynx	0.000	0.565	0.435
C11.1 Posterior wall of nasopharynx	0.000	0.565	0.435
C11.0 Superior wall of nasopharynx	0.000	0.565	0.435
C18.2 Ascending colon	0.000	0.565	0.435
C16.3 Pyloric antrum	0.000	0.569	0.431
C03.9 Gum, unspecified	0.000	0.571	0.429
C03.0 Upper gum	0.000	0.571	0.429
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.421	0.578	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.579	0.420
H40-H42 Glaucoma	0.418	0.582	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.417	0.583	0.000
C16.2 Body of stomach	0.000	0.583	0.416
C39.9 Ill-defined sites within the respiratory system	0.000	0.584	0.416
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.584	0.416
C39.0 Upper respiratory tract, part unspecified	0.000	0.584	0.416
C41.4 Pelvic bones, sacrum and coccyx	0.000	0.584	0.416
C40.9 Bone and articular cartilage of limb, unspecified	0.000	0.587	0.413
C40.8 Overlapping lesion of bone and articular cartilage of limbs	0.000	0.587	0.413
C40.3 Short bones of lower limb	0.000	0.587	0.413
C40.1 Short bones of upper limb	0.000	0.587	0.413
C40.2 Long bones of lower limb	0.000	0.588	0.412
D04.4 Skin of scalp and neck	0.000	0.588	0.412
C60-C63 Malignant neoplasms of male genital organs	0.000	0.589	0.411
C13.9 Hypopharynx, unspecified	0.000	0.591	0.409
C41.2 Vertebral column	0.000	0.593	0.406
C41.8 Overlapping lesion of bone and articular cartilage	0.000	0.594	0.406
C41.3 Ribs, sternum and clavicle	0.000	0.594	0.406
C69.6 Orbit	0.000	0.594	0.406
D00.0 Lip, oral cavity and pharynx	0.000	0.594	0.405
D09.9 Carcinoma in situ, unspecified	0.000	0.596	0.404
D09.3 Thyroid and other endocrine glands	0.000	0.596	0.403
D09.2 Eye	0.000	0.596	0.403
C41.0 Bones of skull and face	0.000	0.600	0.400
C18.8 Overlapping lesion of colon	0.000	0.600	0.400
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.600	0.399
C38.2 Posterior mediastinum	0.000	0.600	0.399
C38.1 Anterior mediastinum	0.000	0.600	0.399
C38.0 Heart	0.000	0.600	0.399
C38.4 Pleura	0.000	0.605	0.395
C06.9 Mouth, unspecified	0.000	0.608	0.392
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)	0.000	0.608	0.392
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)	0.000	0.608	0.392
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)	0.000	0.608	0.392
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)	0.000	0.608	0.392
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)	0.000	0.608	0.392
C18.6 Descending colon	0.000	0.609	0.391
K62 Other diseases of anus and rectum	0.000	0.609	0.391
D09.7 Carcinoma in situ of other specified sites	0.000	0.610	0.390
K62.8 Other specified diseases of anus and rectum	0.000	0.612	0.388
K62.1 Rectal polyp	0.000	0.613	0.387
C41.1 Mandible	0.000	0.614	0.386
D06.0 Endocervix	0.000	0.615	0.385
K62.4 Stenosis of anus and rectum	0.000	0.616	0.384
D00.1 Oesophagus	0.000	0.617	0.383
I02 Rheumatic chorea	0.383	0.617	0.000
I01 Rheumatic fever with heart involvement	0.383	0.617	0.000
C38.3 Mediastinum, part unspecified	0.000	0.619	0.381
K62.0 Anal polyp	0.000	0.620	0.380
D04.1 Skin of eyelid, including canthus	0.000	0.621	0.379
I20.1 Angina pectoris with documented spasm	0.374	0.626	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.001	0.626	0.373
I00 Rheumatic fever without mention of heart involvement	0.373	0.627	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.629	0.371
C69.5 Lachrymal gland and duct	0.000	0.629	0.371
C69.4 Ciliary body	0.000	0.629	0.371
C69.2 Retina	0.000	0.629	0.371
C69.1 Cornea	0.000	0.629	0.371
C11.9 Nasopharynx, unspecified	0.000	0.630	0.369
D09.1 Other and unspecified urinary organs	0.000	0.632	0.368
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.632	0.368
C46 Kaposi's sarcoma	0.000	0.632	0.368
C26.8 Overlapping lesion of digestive system	0.000	0.639	0.361
C26.1 Spleen	0.000	0.639	0.361
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.639	0.360
D06.7 Other parts of cervix	0.000	0.643	0.356
C03.1 Lower gum	0.000	0.644	0.355
D06.1 Exocervix	0.000	0.645	0.355
C18.5 Splenic flexure	0.000	0.647	0.352
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.347	0.653	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.343	0.656	0.001
K62.3 Rectal prolapse	0.000	0.657	0.343
C48.0 Retroperitoneum	0.000	0.658	0.341
C69.0 Conjunctiva	0.000	0.659	0.341
C48.2 Peritoneum, unspecified	0.000	0.662	0.338
C69.9 Eye, unspecified	0.000	0.662	0.338
I70.01 Atherosclerosis of aorta (with gangrene)	0.337	0.663	0.001
D03 Melanoma in situ	0.000	0.665	0.335
K62.2 Anal prolapse	0.000	0.666	0.334
E78.0 Pure hypercholesterolaemia	0.331	0.669	0.000
I23.8 Other current complications following acute myocardial infarction	0.330	0.670	0.001
C70.0 Cerebral meninges	0.001	0.671	0.328
D09.0 Bladder	0.000	0.671	0.329
I71 Aortic aneurysm and dissection	0.322	0.677	0.000
C26.9 Ill-defined sites within the digestive system	0.000	0.681	0.319
C18.4 Transverse colon	0.000	0.683	0.317
C60 Malignant neoplasm of penis	0.000	0.684	0.316
C09.8 Overlapping lesion of tonsil	0.000	0.685	0.314
C09.0 Tonsillar fossa	0.000	0.685	0.314
I05-I09 Chronic rheumatic heart diseases	0.313	0.687	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.307	0.692	0.001
C63 Malignant neoplasm of other and unspecified male genital organs	0.000	0.697	0.303
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.698	0.302
C09.1 Tonsillar pillar (anterior) (posterior)	0.000	0.699	0.301
H42 Glaucoma in diseases classified elsewhere	0.299	0.700	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.294	0.706	0.000
I60-I69 Cerebrovascular diseases	0.288	0.712	0.000
D04.5 Skin of trunk	0.000	0.714	0.286
D03.4 Melanoma in situ of scalp and neck	0.000	0.718	0.282
C48.1 Specified parts of peritoneum	0.000	0.724	0.276
I01.9 Acute rheumatic heart disease, unspecified	0.275	0.725	0.000
I01.8 Other acute rheumatic heart disease	0.275	0.725	0.000
I01.2 Acute rheumatic myocarditis	0.275	0.725	0.000
I01.1 Acute rheumatic endocarditis	0.275	0.725	0.000
I01.0 Acute rheumatic pericarditis	0.275	0.725	0.000
I02.9 Rheumatic chorea without heart involvement	0.275	0.725	0.000
I02.0 Rheumatic chorea with heart involvement	0.275	0.725	0.000
C74 Malignant neoplasm of adrenal gland	0.001	0.725	0.274
I67 Other cerebrovascular diseases	0.265	0.735	0.000
I78 Diseases of capillaries	0.264	0.736	0.001
C46.9 Kaposi's sarcoma, unspecified	0.000	0.736	0.264
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.736	0.264
C46.7 Kaposi's sarcoma of other sites	0.000	0.736	0.264
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.736	0.264
C46.2 Kaposi's sarcoma of palate	0.000	0.736	0.264
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.736	0.264
C46.0 Kaposi's sarcoma of skin	0.000	0.736	0.264
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.736	0.264
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.736	0.264
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.736	0.264
C47.5 Peripheral nerves of pelvis	0.000	0.736	0.264
C47.4 Peripheral nerves of abdomen	0.000	0.736	0.264
C47.3 Peripheral nerves of thorax	0.000	0.736	0.264
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.736	0.264
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.736	0.264
C47.0 Peripheral nerves of head, face and neck	0.000	0.736	0.264
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.264	0.736	0.000
C60.9 Penis, unspecified	0.000	0.737	0.263
I67.9 Cerebrovascular disease, unspecified	0.261	0.739	0.000
C62 Malignant neoplasm of testis	0.000	0.745	0.255
I71.1 Thoracic aortic aneurysm, ruptured	0.252	0.748	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.252	0.748	0.000
C18.1 Appendix	0.000	0.749	0.251
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.751	0.249
I09 Other rheumatic heart diseases	0.244	0.756	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.242	0.758	0.000
D03.9 Melanoma in situ, unspecified	0.000	0.760	0.240
D03.0 Melanoma in situ of lip	0.000	0.760	0.240
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.762	0.238
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.235	0.765	0.000
C45 Mesothelioma	0.000	0.765	0.234
I71.8 Aortic aneurysm of unspecified site, ruptured	0.231	0.769	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.231	0.769	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.769	0.230
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.231	0.769	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.770	0.230
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.771	0.229
I62 Other nontraumatic intracranial haemorrhage	0.228	0.772	0.000
C60.8 Overlapping lesion of penis	0.000	0.773	0.227
C60.2 Body of penis	0.000	0.773	0.227
C63.2 Scrotum	0.000	0.774	0.225
C60.0 Prepuce	0.000	0.775	0.225
C75 Malignant neoplasm of other endocrine glands and related structures	0.001	0.777	0.222
D03.2 Melanoma in situ of ear and external auricular canal	0.000	0.778	0.221
I07 Rheumatic tricuspid valve diseases	0.219	0.781	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations