TreeWAS – Variant ID: rs2213770

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65.3 Chronic mucoid otitis media	0.000	0.889	0.111
H65 Nonsuppurative otitis media	0.000	0.937	0.063
H65.2 Chronic serous otitis media	0.000	0.946	0.054
H65.0 Acute serous otitis media	0.000	0.949	0.051
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.954	0.046
H65.1 Other acute nonsuppurative otitis media	0.000	0.956	0.044
R73.9 Hyperglycaemia, unspecified	0.000	0.961	0.039
H65.4 Other chronic nonsuppurative otitis media	0.000	0.965	0.035
M25.46 Effusion of joint (Lower leg)	0.000	0.971	0.029
K58.0 Irritable bowel syndrome with diarrhoea	0.020	0.980	0.000
M25.4 Effusion of joint	0.000	0.986	0.014
M25.40 Effusion of joint (Multiple sites)	0.000	0.989	0.010
M25.44 Effusion of joint (Hand)	0.000	0.990	0.010
M25.43 Effusion of joint (Forearm)	0.000	0.990	0.010
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.990	0.010
M25.49 Effusion of joint (Site unspecified)	0.000	0.990	0.010
M25.48 Effusion of joint (Other)	0.000	0.990	0.010
M25.41 Effusion of joint (Shoulder region)	0.000	0.990	0.010
M25.42 Effusion of joint (Upper arm)	0.000	0.990	0.010
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
M25.47 Effusion of joint (Ankle and foot)	0.000	0.990	0.010
Q21.1 Atrial septal defect	0.009	0.991	0.000
R73 Elevated blood glucose level	0.000	0.991	0.009
H02.0 Entropion and trichiasis of eyelid	0.008	0.992	0.000
H92.1 Otorrhoea	0.000	0.992	0.008
K61.0 Anal abscess	0.008	0.992	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
J02.9 Acute pharyngitis, unspecified	0.000	0.993	0.007
Z45.2 Adjustment and management of vascular access device	0.000	0.993	0.007
Q21 Congenital malformations of cardiac septa	0.007	0.993	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
N30.2 Other chronic cystitis	0.006	0.994	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.006	0.994	0.000
D63.0 Anaemia in neoplastic disease	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
N30.0 Acute cystitis	0.005	0.995	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
Q21.9 Congenital malformation of cardiac septum, unspecified	0.005	0.995	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
D63 Anaemia in chronic diseases classified elsewhere	0.005	0.995	0.000
Q21.8 Other congenital malformations of cardiac septa	0.005	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.005	0.995	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
Q21.2 Atrioventricular septal defect	0.005	0.995	0.000
H92 Otalgia and effusion of ear	0.000	0.995	0.005
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
Q24.8 Other specified congenital malformations of heart	0.005	0.995	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q27 Other congenital malformations of peripheral vascular system	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
N30 Cystitis	0.005	0.995	0.000
K58 Irritable bowel syndrome	0.005	0.995	0.000
Q24.5 Malformation of coronary vessels	0.004	0.995	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.995	0.000
R56.8 Other and unspecified convulsions	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
H92.0 Otalgia	0.000	0.996	0.004
C67.9 Bladder, unspecified	0.004	0.996	0.000
I20.1 Angina pectoris with documented spasm	0.004	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.996	0.000
N30.4 Irradiation cystitis	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.996	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.996	0.004
H66 Suppurative and unspecified otitis media	0.000	0.996	0.004
N30.1 Interstitial cystitis (chronic)	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
H92.2 Otorrhagia	0.000	0.996	0.004
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.004	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.004	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.004	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.004	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.1 Persistent left superior vena cava	0.004	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.004	0.996	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.004	0.996	0.000
Q27.4 Congenital phlebectasia	0.004	0.996	0.000
Q27.2 Other congenital malformations of renal artery	0.004	0.996	0.000
Q27.1 Congenital renal artery stenosis	0.004	0.996	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.000	0.996	0.004
Q27.8 Other specified congenital malformations of peripheral vascular system	0.004	0.996	0.000
J02 Acute pharyngitis	0.000	0.996	0.004
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.996	0.000
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.996	0.000
Q22.0 Pulmonary valve atresia	0.003	0.996	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.004	0.996	0.000
N30.9 Cystitis, unspecified	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.996	0.004
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
Q27.3 Peripheral arteriovenous malformation	0.003	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.997	0.003
D48.1 Connective and other soft tissue	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.997	0.003
H66.0 Acute suppurative otitis media	0.000	0.997	0.003
Z85.5 Personal history of malignant neoplasm of urinary tract	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
H70 Mastoiditis and related conditions	0.000	0.997	0.003
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.003	0.997	0.000
S56 Injury of muscle and tendon at forearm level	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.997	0.003
H68 Eustachian salpingitis and obstruction	0.000	0.997	0.003
H67 Otitis media in diseases classified elsewhere	0.000	0.997	0.003
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.003	0.997	0.000
Y44.2 Anticoagulants	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.003	0.997	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.000	0.997	0.003
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.997	0.003
J02.0 Streptococcal pharyngitis	0.000	0.997	0.003
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
N30.8 Other cystitis	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.997	0.002
H70.2 Petrositis	0.000	0.997	0.002
H70.0 Acute mastoiditis	0.000	0.997	0.002
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.003	0.997	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.003	0.997	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.003	0.997	0.000
S50.9 Superficial injury of forearm, unspecified	0.003	0.997	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q04.6 Congenital cerebral cysts	0.002	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.997	0.002
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.997	0.002
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.997	0.002
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.997	0.002
H68.1 Obstruction of Eustachian tube	0.000	0.997	0.002
H68.0 Eustachian salpingitis	0.000	0.997	0.002
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.997	0.002
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
K56.5 Intestinal adhesions [bands] with obstruction	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
M35.0 Sicca syndrome [Sjogren]	0.003	0.997	0.000
R56 Convulsions, not elsewhere classified	0.002	0.997	0.000
Q05 Spina bifida	0.002	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.998	0.002
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q03 Congenital hydrocephalus	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
H70.1 Chronic mastoiditis	0.000	0.998	0.002
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
R56.0 Febrile convulsions	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.998	0.002
O47.0 False labour before 37 completed weeks of gestation	0.000	0.998	0.002
Q77.4 Achondroplasia	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
S50 Superficial injury of forearm	0.002	0.998	0.000
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.002	0.998	0.000
Q90.9 Down's syndrome, unspecified	0.002	0.998	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.998	0.002
C71.4 Occipital lobe	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.998	0.002
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.000	0.998	0.002
Q36 Cleft lip	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
B44.1 Other pulmonary aspergillosis	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.002	0.998	0.000
N30.3 Trigonitis	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
L27 Dermatitis due to substances taken internally	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
Q00.2 Iniencephaly	0.002	0.998	0.000
Q00.1 Craniorachischisis	0.002	0.998	0.000
Q00.0 Anencephaly	0.002	0.998	0.000
Q01.9 Encephalocele, unspecified	0.002	0.998	0.000
Q01.8 Encephalocele of other sites	0.002	0.998	0.000
Q01.2 Occipital encephalocele	0.002	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.998	0.000
Q01.0 Frontal encephalocele	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.998	0.000
Q06.4 Hydromyelia	0.002	0.998	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.998	0.000
Q06.2 Diastematomyelia	0.002	0.998	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.998	0.000
Q06.0 Amyelia	0.002	0.998	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
S53.2 Traumatic rupture of radial collateral ligament	0.002	0.998	0.000
S53.3 Traumatic rupture of ulnar collateral ligament	0.002	0.998	0.000
S50.0 Contusion of elbow	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
Q12.0 Congenital cataract	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
C22.9 Liver, unspecified	0.000	0.998	0.002
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
Q90.2 Trisomy 21, translocation	0.002	0.998	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.998	0.002
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
X63.0 Home	0.000	0.998	0.002
K61 Abscess of anal and rectal regions	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.998	0.002
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
G83.8 Other specified paralytic syndromes	0.002	0.998	0.000
I84.5 External haemorrhoids without complication	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
S50.7 Multiple superficial injuries of forearm	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
S50-S59 Injuries to the elbow and forearm	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
O97 Death from sequelae of direct obstetric causes	0.000	0.998	0.002
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.998	0.002
O95 Obstetric death of unspecified cause	0.000	0.998	0.002
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C32.1 Supraglottis	0.000	0.998	0.002
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.998	0.000
S29.9 Unspecified injury of thorax	0.000	0.998	0.002
S50.1 Contusion of other and unspecified parts of forearm	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.998	0.002
Q12.9 Congenital lens malformation, unspecified	0.002	0.998	0.000
Q12.8 Other congenital lens malformations	0.002	0.998	0.000
Q12.4 Spherophakia	0.002	0.998	0.000
Q12.3 Congenital aphakia	0.002	0.998	0.000
Q12.2 Coloboma of lens	0.002	0.998	0.000
Q12.1 Congenital displaced lens	0.002	0.998	0.000
Q35.9 Cleft palate, unspecified	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
H69.0 Patulous Eustachian tube	0.000	0.998	0.001
Q35.8 (Cleft palate, unspecified, bilateral)	0.001	0.998	0.000
Q35.7 Cleft uvula	0.001	0.998	0.000
Q35.6 Cleft palate, medial	0.001	0.998	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.001	0.998	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.001	0.998	0.000
Q35.3 Cleft soft palate	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations