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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2233359
log Bayes Factor = 23.4181
Chromosome 17   position 47,286,962  (GRCh37) Explore rs2233359 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I20.0 Unstable angina
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I10 Essential (primary) hypertension
0.999 0.001 0.000
E78.5 Hyperlipidaemia, unspecified
0.998 0.002 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.997 0.003 0.000
I12 Hypertensive renal disease
0.997 0.003 0.000
E78.0 Pure hypercholesterolaemia
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
I12.9 Hypertensive renal disease without renal failure
0.990 0.010 0.000
J43 Emphysema
0.989 0.011 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.983 0.017 0.000
J43.9 Emphysema, unspecified
0.979 0.021 0.000
J47 Bronchiectasis
0.978 0.022 0.000
J00-J06 Acute upper respiratory infections
0.974 0.026 0.000
I21 Acute myocardial infarction
0.972 0.028 0.000
J46 Status asthmaticus
0.962 0.038 0.000
I22 Subsequent myocardial infarction
0.958 0.042 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.957 0.043 0.000
E83 Disorders of mineral metabolism
0.955 0.045 0.000
I21.9 Acute myocardial infarction, unspecified
0.950 0.050 0.000
D70 Agranulocytosis
0.949 0.051 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.944 0.056 0.000
J01 Acute sinusitis
0.940 0.060 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.939 0.061 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.930 0.070 0.000
D75 Other diseases of blood and blood-forming organs
0.923 0.077 0.000
I12.0 Hypertensive renal disease with renal failure
0.923 0.077 0.000
D80-D89 Certain disorders involving the immune mechanism
0.922 0.078 0.000
E83.5 Disorders of calcium metabolism
0.918 0.082 0.000
J01.9 Acute sinusitis, unspecified
0.916 0.084 0.000
Chapter VIII Diseases of the ear and mastoid process
0.909 0.091 0.000
I15 Secondary hypertension
0.907 0.093 0.000
E16 Other disorders of pancreatic internal secretion
0.905 0.095 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.905 0.095 0.000
E88 Other metabolic disorders
0.902 0.098 0.000
J45 Asthma
0.893 0.107 0.000
H65-H75 Diseases of middle ear and mastoid
0.893 0.107 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.890 0.110 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.888 0.112 0.000
E16.2 Hypoglycaemia, unspecified
0.882 0.118 0.000
Chapter XX External causes of morbidity and mortality
0.876 0.124 0.000
I11 Hypertensive heart disease
0.875 0.125 0.000
I05-I09 Chronic rheumatic heart diseases
0.871 0.129 0.000
Q80-Q89 Other congenital malformations
0.868 0.132 0.000
Chapter VI Diseases of the nervous system
0.864 0.136 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.857 0.143 0.000
J03 Acute tonsillitis
0.854 0.146 0.000
J02 Acute pharyngitis
0.853 0.147 0.000
H71 Cholesteatoma of middle ear
0.849 0.151 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.849 0.151 0.000
D86 Sarcoidosis
0.841 0.159 0.000
I95 Hypotension
0.839 0.161 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.833 0.167 0.000
I15.1 Hypertension secondary to other renal disorders
0.829 0.171 0.000
J45.0 Predominantly allergic asthma
0.827 0.173 0.000
M86-M90 Other osteopathies
0.826 0.174 0.000
E83.4 Disorders of magnesium metabolism
0.816 0.184 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.816 0.184 0.000
Q82 Other congenital malformations of skin
0.815 0.185 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.811 0.189 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.810 0.190 0.000
J41 Simple and mucopurulent chronic bronchitis
0.807 0.193 0.000
Q60-Q64 Congenital malformations of the urinary system
0.806 0.194 0.000
J42 Unspecified chronic bronchitis
0.805 0.195 0.000
D68 Other coagulation defects
0.802 0.198 0.000
D69 Purpura and other haemorrhagic conditions
0.802 0.198 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.801 0.199 0.000
E40-E46 Malnutrition
0.799 0.201 0.000
E50-E64 Other nutritional deficiencies
0.797 0.203 0.000
G40-G47 Episodic and paroxysmal disorders
0.795 0.205 0.000
G43 Migraine
0.791 0.209 0.000
G43.9 Migraine, unspecified
0.791 0.209 0.000
M89 Other disorders of bone
0.788 0.212 0.000
Chapter XXII Codes for special purposes
0.788 0.212 0.000
H72 Perforation of tympanic membrane
0.785 0.215 0.000
J43.2 Centrilobular emphysema
0.782 0.218 0.000
H74 Other disorders of middle ear and mastoid
0.782 0.218 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.775 0.225 0.000
Y95 Nosocomial condition
0.773 0.227 0.000
J03.9 Acute tonsillitis, unspecified
0.768 0.232 0.000
J02.9 Acute pharyngitis, unspecified
0.766 0.234 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.765 0.235 0.000
Q00-Q07 Congenital malformations of the nervous system
0.765 0.235 0.000
I95.9 Hypotension, unspecified
0.764 0.236 0.000
E83.3 Disorders of phosphorus metabolism
0.763 0.237 0.000
I73 Other peripheral vascular diseases
0.763 0.237 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.762 0.238 0.000
J60-J70 Lung diseases due to external agents
0.762 0.238 0.000
M89.9 Disorder of bone, unspecified
0.760 0.240 0.000
D55-D59 Haemolytic anaemias
0.756 0.244 0.000
E20-E35 Disorders of other endocrine glands
0.754 0.246 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.752 0.248 0.000
V40-V49 Car occupant injured in transport accident
0.746 0.254 0.000
D86.9 Sarcoidosis, unspecified
0.745 0.255 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.743 0.257 0.000
H66 Suppurative and unspecified otitis media
0.741 0.259 0.000
D69.6 Thrombocytopenia, unspecified
0.738 0.262 0.000
X20-X29 Contact with venomous animals and plants
0.738 0.262 0.000
Q61 Cystic kidney disease
0.738 0.262 0.000
D80 Immunodeficiency with predominantly antibody defects
0.738 0.262 0.000
M60-M63 Disorders of muscles
0.737 0.263 0.000
M80-M85 Disorders of bone density and structure
0.736 0.264 0.000
D75.2 Essential thrombocytosis
0.735 0.265 0.000
G57 Mononeuropathies of lower limb
0.735 0.265 0.000
J20-J22 Other acute lower respiratory infections
0.734 0.266 0.000
I78 Diseases of capillaries
0.733 0.267 0.000
E73 Lactose intolerance
0.732 0.268 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.731 0.269 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.731 0.269 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.729 0.271 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.728 0.271 0.000
Q82.8 Other specified congenital malformations of skin
0.728 0.271 0.000
Q74 Other congenital malformations of limb(s)
0.728 0.272 0.000
D68.2 Hereditary deficiency of other clotting factors
0.727 0.273 0.000
I23 Certain current complications following acute myocardial infarction
0.724 0.276 0.000
I25.4 Coronary artery aneurysm
0.722 0.277 0.000
W00-W19 Falls
0.722 0.278 0.000
E74 Other disorders of carbohydrate metabolism
0.719 0.281 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.718 0.282 0.000
I25.3 Aneurysm of heart
0.718 0.282 0.000
I08 Multiple valve diseases
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E78.6 Lipoprotein deficiency
0.717 0.283 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.715 0.285 0.000
M45-M49 Spondylopathies
0.714 0.286 0.000
H73 Other disorders of tympanic membrane
0.713 0.286 0.000
I22.8 Subsequent myocardial infarction of other sites
0.713 0.287 0.000
I95.1 Orthostatic hypotension
0.713 0.287 0.000
H70 Mastoiditis and related conditions
0.711 0.289 0.000
M05-M14 Inflammatory polyarthropathies
0.711 0.289 0.000
J43.8 Other emphysema
0.709 0.291 0.000
J43.1 Panlobular emphysema
0.709 0.291 0.000
J43.0 MacLeod's syndrome
0.709 0.291 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.706 0.294 0.000
G54 Nerve root and plexus disorders
0.706 0.294 0.000
D74 Methaemoglobinaemia
0.705 0.295 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.705 0.295 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.705 0.295 0.000
I99 Other and unspecified disorders of circulatory system
0.699 0.301 0.000
D66 Hereditary factor VIII deficiency
0.698 0.301 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.697 0.303 0.000
I73.9 Peripheral vascular disease, unspecified
0.695 0.305 0.000
I05 Rheumatic mitral valve diseases
0.695 0.305 0.000
D86.1 Sarcoidosis of lymph nodes
0.693 0.307 0.000
J04 Acute laryngitis and tracheitis
0.691 0.309 0.000
E85 Amyloidosis
0.691 0.309 0.000
Q66 Congenital deformities of feet
0.691 0.309 0.000
I15.9 Seconday hypertension, unspecified
0.690 0.310 0.000
J85 Abscess of lung and mediastinum
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.686 0.314 0.000
Q35-Q37 Cleft lip and cleft palate
0.686 0.314 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.686 0.314 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.684 0.315 0.000
E83.8 Other disorders of mineral metabolism
0.684 0.315 0.000
E83.2 Disorders of zinc metabolism
0.684 0.315 0.000
E83.0 Disorders of copper metabolism
0.684 0.315 0.000
Q82.2 Mastocytosis
0.684 0.316 0.000
I24 Other acute ischaemic heart diseases
0.683 0.316 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.683 0.317 0.000
D73 Diseases of spleen
0.682 0.318 0.000
Q65 Congenital deformities of hip
0.681 0.319 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.680 0.320 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.678 0.322 0.000
E15 Nondiabetic hypoglycaemic coma
0.677 0.323 0.000
Q61.0 Congenital single renal cyst
0.676 0.324 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.675 0.325 0.000
Chapter I Certain infectious and parasitic diseases
0.675 0.325 0.000
D68.4 Acquired coagulation factor deficiency
0.675 0.325 0.000
J01.8 Other acute sinusitis
0.674 0.326 0.000
J01.4 Acute pansinusitis
0.674 0.326 0.000
J01.3 Acute sphenoidal sinusitis
0.674 0.326 0.000
J01.2 Acute ethmoidal sinusitis
0.674 0.326 0.000
J01.1 Acute frontal sinusitis
0.674 0.326 0.000
J01.0 Acute maxillary sinusitis
0.674 0.326 0.000
D67 Hereditary factor IX deficiency
0.673 0.327 0.000
D69.5 Secondary thrombocytopenia
0.672 0.328 0.000
W75-W84 Other accidental threats to breathing
0.671 0.329 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.670 0.330 0.000
J41.0 Simple chronic bronchitis
0.668 0.332 0.000
M88 Paget's disease of bone [osteitis deformans]
0.668 0.332 0.000
I09 Other rheumatic heart diseases
0.667 0.333 0.000
D84 Other immunodeficiencies
0.667 0.333 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.664 0.336 0.000
D68.5 Primary Thrombophilia
0.664 0.336 0.000
V80-V89 Other land transport accidents
0.663 0.337 0.000
M10 Gout
0.663 0.337 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.663 0.337 0.000
I73.0 Raynaud's syndrome
0.663 0.337 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.663 0.337 0.000
D75.0 Familial erythrocytosis
0.662 0.338 0.000
D86.0 Sarcoidosis of lung
0.662 0.338 0.000
M86 Osteomyelitis
0.662 0.338 0.000
D83 Common variable immunodeficiency
0.661 0.339 0.000
D82 Immunodeficiency associated with other major defects
0.661 0.339 0.000
D81 Combined immunodeficiencies
0.661 0.339 0.000
G58 Other mononeuropathies
0.661 0.339 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.660 0.340 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.658 0.342 0.000
M62 Other disorders of muscle
0.658 0.342 0.000
I95.0 Idiopathic hypotension
0.657 0.343 0.000
E78.2 Mixed hyperlipidaemia
0.655 0.345 0.000
E46 Unspecified protein-energy malnutrition
0.655 0.345 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.653 0.347 0.000
I25.5 Ischaemic cardiomyopathy
0.652 0.348 0.000
I15.8 Other secondary hypertension
0.651 0.349 0.000
I15.2 Hypertension secondary to endocrine disorders
0.651 0.349 0.000
I15.0 Renovascular hypertension
0.651 0.349 0.000
V98-V99 Other and unspecified transport accidents
0.649 0.350 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.649 0.351 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.649 0.351 0.000
E16.4 Abnormal secretion of gastrin
0.649 0.351 0.000
E16.3 Increased secretion of glucagon
0.649 0.351 0.000
E16.1 Other hypoglycaemia
0.649 0.351 0.000
M91-M94 Chondropathies
0.648 0.352 0.000
E88.9 Metabolic disorder, unspecified
0.647 0.353 0.000
E88.8 Other specified metabolic disorders
0.647 0.353 0.000
E88.3 Tumour lysis syndrome
0.647 0.353 0.000
E88.2 Lipomatosis, not elsewhere classified
0.647 0.353 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.647 0.353 0.000
G70-G73 Diseases of myoneural junction and muscle
0.647 0.353 0.000
G57.6 Lesion of plantar nerve
0.646 0.354 0.000
H72.8 Other perforations of tympanic membrane
0.645 0.355 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.645 0.355 0.000
E23 Hypofunction and other disorders of pituitary gland
0.643 0.357 0.000
W50-W64 Exposure to animate mechanical forces
0.643 0.357 0.000
M00-M03 Infectious arthropathies
0.642 0.357 0.000
E29 Testicular dysfunction
0.642 0.358 0.000
G52 Disorders of other cranial nerves
0.641 0.359 0.000
E55 Vitamin D deficiency
0.641 0.359 0.000
J45.8 Mixed asthma
0.640 0.360 0.000
J45.1 Nonallergic asthma
0.640 0.360 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.640 0.360 0.000
H68 Eustachian salpingitis and obstruction
0.640 0.360 0.000
H67 Otitis media in diseases classified elsewhere
0.640 0.360 0.000
X23 Contact with hornets, wasps and bees
0.640 0.360 0.000
Q82.5 Congenital nonneoplastic naevus
0.639 0.361 0.000
G41 Status epilepticus
0.639 0.361 0.000
D75.1 Secondary polycythaemia
0.638 0.362 0.000
H74.0 Tympanosclerosis
0.637 0.363 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.636 0.364 0.000
H66.3 Other chronic suppurative otitis media
0.636 0.364 0.000
E78.1 Pure hyperglyceridaemia
0.635 0.365 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.635 0.365 0.000
M80 Osteoporosis with pathological fracture
0.635 0.365 0.000
I21.4 Acute subendocardial myocardial infarction
0.631 0.369 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.631 0.369 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.630 0.370 0.000
Y35-Y36 Legal intervention and operations of war
0.628 0.372 0.000
Y10-Y34 Event of undetermined intent
0.628 0.372 0.000
X85-X99 Assault
0.628 0.372 0.000
X30-X39 Exposure to forces of nature
0.628 0.372 0.000
X00-X09 Exposure to smoke, fire and flames
0.628 0.372 0.000
W65-W74 Accidental drowning and submersion
0.628 0.372 0.000
V95-V97 Air and space transport accidents
0.628 0.372 0.000
V90-V94 Water transport accidents
0.628 0.372 0.000
V70-V79 Bus occupant injured in transport accident
0.628 0.372 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.628 0.372 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.628 0.372 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.628 0.372 0.000
V01-V09 Pedestrian injured in transport accident
0.628 0.372 0.000
Q07 Other congenital malformations of nervous system
0.627 0.373 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.627 0.373 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.627 0.373 0.000
X59 Exposure to unspecified factor
0.627 0.373 0.000
D76.3 Other histiocytosis syndromes
0.627 0.373 0.000
M10.9 Gout, unspecified
0.627 0.373 0.000
I06 Rheumatic aortic valve diseases
0.625 0.375 0.000
Q89 Other congenital malformations, not elsewhere classified
0.623 0.377 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.622 0.378 0.000
Q84 Other congenital malformations of integument
0.622 0.378 0.000
Q81 Epidermolysis bullosa
0.622 0.378 0.000
Q80 Congenital ichthyosis
0.622 0.378 0.000
I08.0 Disorders of both mitral and aortic valves
0.621 0.379 0.000
I07 Rheumatic tricuspid valve diseases
0.621 0.379 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.621 0.379 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.621 0.379 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.618 0.382 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.618 0.382 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.616 0.384 0.000
Q74.1 Congenital malformation of knee
0.616 0.384 0.000
I78.8 Other diseases of capillaries
0.615 0.385 0.000
M89.98 Disorder of bone, unspecified (Other)
0.615 0.385 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.615 0.385 0.000
G30-G32 Other degenerative diseases of the nervous system
0.615 0.385 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.614 0.386 0.000
Q78 Other osteochondrodysplasias
0.614 0.386 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.614 0.386 0.000
Q75 Other congenital malformations of skull and face bones
0.614 0.386 0.000
Q73 Reduction defects of unspecified limb
0.614 0.386 0.000
Q72 Reduction defects of lower limb
0.614 0.386 0.000
Q71 Reduction defects of upper limb
0.614 0.386 0.000
Q70 Syndactyly
0.614 0.386 0.000
Q69 Polydactyly
0.614 0.386 0.000
Q68 Other congenital musculoskeletal deformities
0.614 0.386 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.614 0.386 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.614 0.386 0.000
M05 Seropositive rheumatoid arthritis
0.612 0.388 0.000
J03.8 Acute tonsillitis due to other specified organisms
0.612 0.388 0.000
J03.0 Streptococcal tonsillitis
0.612 0.388 0.000
Q83 Congenital malformations of breast
0.612 0.388 0.000
M90 Osteopathies in diseases classified elsewhere
0.612 0.388 0.000
J02.8 Acute pharyngitis due to other specified organisms
0.611 0.389 0.000
J02.0 Streptococcal pharyngitis
0.611 0.389 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.610 0.390 0.000
Y52 Agents primarily affecting the cardiovascular system
0.608 0.392 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.608 0.392 0.000
J40 Bronchitis, not specified as acute or chronic
0.607 0.393 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.606 0.394 0.000
M89.0 Algoneurodystrophy
0.605 0.395 0.000
D56 Thalassaemia
0.605 0.395 0.000
I05.1 Rheumatic mitral insufficiency
0.603 0.397 0.000
D86.3 Sarcoidosis of skin
0.603 0.397 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.603 0.397 0.000
J45.9 Asthma, unspecified
0.601 0.399 0.000
M45 Ankylosing spondylitis
0.600 0.400 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.600 0.400 0.000
M87 Osteonecrosis
0.599 0.401 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.599 0.401 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.599 0.401 0.000
E53 Deficiency of other B group vitamins
0.598 0.402 0.000
M85 Other disorders of bone density and structure
0.597 0.403 0.000
Q50-Q56 Congenital malformations of genital organs
0.596 0.403 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.596 0.404 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.596 0.404 0.000
Q61.2 Polycystic kidney, adult type
0.596 0.404 0.000
I70 Atherosclerosis
0.595 0.405 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.595 0.405 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.594 0.406 0.000
E89.0 Postprocedural hypothyroidism
0.594 0.406 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.592 0.407 0.000
Q85 Phakomatoses, not elsewhere classified
0.592 0.408 0.000
X60-X84 Intentional self-harm
0.591 0.409 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.591 0.409 0.000
M48 Other spondylopathies
0.591 0.409 0.000
I08.8 Other multiple valve diseases
0.591 0.409 0.000
W02.9 Unspecified place
0.589 0.411 0.000
G51 Facial nerve disorders
0.589 0.411 0.000
M46 Other inflammatory spondylopathies
0.589 0.411 0.000
W07 Fall involving chair
0.589 0.411 0.000
X10-X19 Contact with heat and hot substances
0.587 0.412 0.000
D60-D64 Aplastic and other anaemias
0.587 0.413 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.587 0.413 0.000
G43.8 Other migraine
0.587 0.413 0.000
I95.8 Other hypotension
0.586 0.414 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.586 0.414 0.000
G57.1 Meralgia paraesthetica
0.585 0.414 0.000
H73.8 Other specified disorders of tympanic membrane
0.585 0.415 0.000
Q82.9 Congenital malformation of skin, unspecified
0.584 0.415 0.000
Q82.4 Ectodermal dysplasia (anhidrotic)
0.584 0.415 0.000
Q82.3 Incontinentia pigmenti
0.584 0.415 0.000
Q82.1 Xeroderma pigmentosum
0.584 0.415 0.000
Q82.0 Hereditary lymphoedema
0.584 0.415 0.000
D68.9 Coagulation defect, unspecified
0.585 0.415 0.000
Q66.2 Metatarsus varus
0.584 0.416 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.584 0.416 0.000
E80.1 Porphyria cutanea tarda
0.584 0.416 0.000
Q76 Congenital malformations of spine and bony thorax
0.584 0.416 0.000
J85.2 Abscess of lung without pneumonia
0.583 0.417 0.000
E24 Cushing's syndrome
0.583 0.417 0.000
X50-X57 Overexertion, travel and privation
0.583 0.417 0.000
V20-V29 Motorcycle rider injured in transport accident
0.583 0.417 0.000
S20-S29 Injuries to the thorax
0.583 0.417 0.000
A30-A49 Other bacterial diseases
0.581 0.419 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.581 0.419 0.000
Y98 Lifestyle-related condition
0.581 0.419 0.000
Y97 Environmental-pollution-related condition
0.581 0.419 0.000
Y96 Work-related condition
0.581 0.419 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.580 0.420 0.000
G54.0 Brachial plexus disorders
0.579 0.421 0.000
M07 Psoriatic and enteropathic arthropathies
0.578 0.421 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.578 0.422 0.000
J41.1 Mucopurulent chronic bronchitis
0.578 0.422 0.000
Q64 Other congenital malformations of urinary system
0.578 0.422 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.578 0.422 0.000
E78.4 Other hyperlipidaemia
0.578 0.422 0.000
S40-S49 Injuries to the shoulder and upper arm
0.578 0.422 0.000
E78.8 Other disorders of lipoprotein metabolism
0.577 0.423 0.000
M40-M43 Deforming dorsopathies
0.577 0.423 0.000
G00 Bacterial meningitis, not elsewhere classified
0.577 0.423 0.000
I20.1 Angina pectoris with documented spasm
0.576 0.424 0.000
J86 Pyothorax
0.576 0.424 0.000
H70.1 Chronic mastoiditis
0.575 0.424 0.000
Y00-Y09 Assault
0.575 0.424 0.000
D68.1 Hereditary factor XI deficiency
0.575 0.425 0.000
D69.9 Haemorrhagic condition, unspecified
0.575 0.425 0.000
D69.8 Other specified haemorrhagic conditions
0.575 0.425 0.000
D69.4 Other primary thrombocytopenia
0.575 0.425 0.000
D69.2 Other nonthrombocytopenic purpura
0.575 0.425 0.000
D69.1 Qualitative platelet defects
0.575 0.425 0.000
W13 Fall from, out of or through building or structure
0.573 0.427 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.573 0.427 0.000
E45 Retarded development following protein-energy malnutrition
0.573 0.427 0.000
E43 Unspecified severe protein-energy malnutrition
0.573 0.427 0.000
E42 Marasmic kwashiorkor
0.573 0.427 0.000
E41 Nutritional marasmus
0.573 0.427 0.000
E40 Kwashiorkor
0.573 0.427 0.000
W06 Fall involving bed
0.573 0.427 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.572 0.427 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.573 0.427 0.000
D58 Other hereditary haemolytic anaemias
0.572 0.428 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.571 0.428 0.000
E63 Other nutritional deficiencies
0.571 0.428 0.000
E56 Other vitamin deficiencies
0.571 0.428 0.000
E51 Thiamine deficiency
0.571 0.428 0.000
E50 Vitamin A deficiency
0.571 0.428 0.000
E60 Dietary zinc deficiency
0.571 0.428 0.000
E59 Dietary selenium deficiency
0.571 0.428 0.000
E58 Dietary calcium deficiency
0.571 0.428 0.000
E54 Ascorbic acid deficiency
0.571 0.428 0.000
E52 Niacin deficiency [pellagra]
0.571 0.428 0.000
M49 Spondylopathies in diseases classified elsewhere
0.571 0.429 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.570 0.430 0.000
M10.90 Gout, unspecified (Multiple sites)
0.569 0.431 0.000
E23.0 Hypopituitarism
0.569 0.431 0.000
Y45.1 Salicylates
0.568 0.432 0.000
G43.3 Complicated migraine
0.567 0.433 0.000
G43.2 Status migrainosus
0.567 0.433 0.000
G43.0 Migraine without aura [common migraine]
0.567 0.433 0.000
X23.9 Unspecified place
0.567 0.433 0.000
V49.9 Car occupant [any] injured in unspecified traffic accident
0.566 0.433 0.000
A41 Other septicaemia
0.566 0.434 0.000
M89.6 Osteopathy after poliomyelitis
0.565 0.435 0.000
M89.5 Osteolysis
0.565 0.435 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.565 0.435 0.000
M89.2 Other disorders of bone development and growth
0.565 0.435 0.000
M89.1 Epiphyseal arrest
0.565 0.435 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.565 0.435 0.000
B99-B99 Other infectious diseases
0.563 0.437 0.000
G57.0 Lesion of sciatic nerve
0.563 0.437 0.000
H72.1 Attic perforation of tympanic membrane
0.563 0.437 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.562 0.438 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.562 0.438 0.000
E29.1 Testicular hypofunction
0.561 0.439 0.000
H74.1 Adhesive middle ear disease
0.561 0.439 0.000
M62.8 Other specified disorders of muscle
0.561 0.439 0.000
B15-B19 Viral hepatitis
0.561 0.439 0.000
V10-V19 Pedal cyclist injured in transport accident
0.560 0.439 0.000
E61 Deficiency of other nutrient elements
0.560 0.440 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.559 0.440 0.000
J22 Unspecified acute lower respiratory infection
0.559 0.441 0.000
Y48 Anaesthetics and therapeutic gases
0.558 0.441 0.000
G44 Other headache syndromes
0.557 0.442 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.557 0.443 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.557 0.443 0.000
I78.1 Naevus, nonneoplastic
0.557 0.443 0.000
U80 Agent resistant to penicillin and related antibiotics
0.556 0.444 0.000
I71 Aortic aneurysm and dissection
0.556 0.444 0.000
V48 Car occupant injured in noncollision transport accident
0.556 0.444 0.000
D76.2 Haemophagocytic syndrome, infection-associated
0.556 0.444 0.000
D76.1 Haemophagocytic lymphohistiocytosis
0.556 0.444 0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.556 0.444 0.000
G58.8 Other specified mononeuropathies
0.556 0.444 0.000
Q65.8 Other congenital deformities of hip
0.554 0.445 0.000
M88.9 Paget's disease of bone, unspecified
0.554 0.446 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.552 0.448 0.000
W94 Exposure to high and low air pressure and changes in air pressure
0.551 0.449 0.000
M89.3 Hypertrophy of bone
0.551 0.449 0.000
I25.2 Old myocardial infarction
0.551 0.449 0.000
Q63 Other congenital malformations of kidney
0.550 0.450 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.549 0.451 0.000
H80-H83 Diseases of inner ear
0.549 0.451 0.000
Q06 Other congenital malformations of spinal cord
0.548 0.451 0.000
Q04 Other congenital malformations of brain
0.548 0.451 0.000
Q03 Congenital hydrocephalus
0.548 0.451 0.000
Q01 Encephalocele
0.548 0.451 0.000
Q00 Anencephaly and similar malformations
0.548 0.451 0.000
Q02 Microcephaly
0.548 0.451 0.000
Q05 Spina bifida
0.548 0.451 0.000
W17 Other fall from one level to another
0.548 0.451 0.000
D69.0 Allergic purpura
0.548 0.452 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.547 0.453 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.547 0.453 0.000
Y40 Systemic antibiotics
0.546 0.454 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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