TreeWAS – Variant ID: rs2238675

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E10-E14 Diabetes mellitus	1.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
E11.9 Without complications	0.999	0.001
# Top node	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.995	0.005
E10.3 With ophthalmic complications	0.989	0.011
Chapter I Certain infectious and parasitic diseases	0.985	0.015
Chapter VIII Diseases of the ear and mastoid process	0.985	0.015
B35-B49 Mycoses	0.981	0.019
B37 Candidiasis	0.980	0.020
E10.9 Without complications	0.977	0.023
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.968	0.032
E11.3 With ophthalmic complications	0.967	0.033
B37.0 Candidal stomatitis	0.967	0.033
K76 Other diseases of liver	0.965	0.035
H65-H75 Diseases of middle ear and mastoid	0.965	0.035
K76.0 Fatty (change of) liver, not elsewhere classified	0.964	0.036
K70-K77 Diseases of liver	0.961	0.039
Chapter XX External causes of morbidity and mortality	0.956	0.044
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.956	0.044
D80-D89 Certain disorders involving the immune mechanism	0.941	0.059
E20-E35 Disorders of other endocrine glands	0.934	0.066
Chapter VII Diseases of the eye and adnexa	0.928	0.072
K74 Fibrosis and cirrhosis of liver	0.927	0.073
Chapter V Mental and behavioural disorders	0.927	0.073
K76.6 Portal hypertension	0.925	0.075
Chapter XI Diseases of the digestive system	0.924	0.076
H53-H54 Visual disturbances and blindness	0.923	0.077
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.922	0.078
H53 Visual disturbances	0.921	0.079
Q50-Q56 Congenital malformations of genital organs	0.919	0.081
B37.3 Candidiasis of vulva and vagina	0.916	0.084
B37.8 Candidiasis of other sites	0.915	0.085
H90-H95 Other disorders of ear	0.911	0.089
E11.8 With unspecified complications	0.898	0.102
D86 Sarcoidosis	0.898	0.102
F43 Reaction to severe stress, and adjustment disorders	0.895	0.105
F40-F48 Neurotic, stress-related and somatoform disorders	0.894	0.106
H30-H36 Disorders of choroid and retina	0.892	0.108
K74.6 Other and unspecified cirrhosis of liver	0.890	0.110
E23 Hypofunction and other disorders of pituitary gland	0.887	0.113
H53.8 Other visual disturbances	0.886	0.114
F43.2 Adjustment disorders	0.885	0.115
H72 Perforation of tympanic membrane	0.880	0.120
H36 Retinal disorders in diseases classified elsewhere	0.879	0.121
H65 Nonsuppurative otitis media	0.873	0.127
H36.0 Diabetic retinopathy	0.870	0.130
H92 Otalgia and effusion of ear	0.866	0.134
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.862	0.138
H53.0 Amblyopia ex anopsia	0.861	0.139
Y43 Primarily systemic agents	0.858	0.142
E23.2 Diabetes insipidus	0.858	0.142
Chapter VI Diseases of the nervous system	0.857	0.143
H66 Suppurative and unspecified otitis media	0.855	0.145
G40-G47 Episodic and paroxysmal disorders	0.853	0.147
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.851	0.149
K50-K52 Noninfective enteritis and colitis	0.850	0.150
B15-B19 Viral hepatitis	0.846	0.154
Y40 Systemic antibiotics	0.845	0.155
H92.0 Otalgia	0.841	0.159
G40 Epilepsy	0.839	0.161
F43.1 Posttraumatic stress disorder	0.836	0.164
B25-B34 Other viral diseases	0.835	0.165
K51 Ulcerative colitis	0.832	0.168
E10.2 With renal complications	0.830	0.170
F60-F69 Disorders of adult personality and behaviour	0.824	0.176
W50-W64 Exposure to animate mechanical forces	0.823	0.177
H55-H59 Other disorders of eye and adnexa	0.822	0.178
H72.0 Central perforation of tympanic membrane	0.820	0.180
B99-B99 Other infectious diseases	0.815	0.185
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.815	0.185
E10.8 With unspecified complications	0.813	0.187
E10.5 With peripheral circulatory complications	0.810	0.189
G47 Sleep disorders	0.810	0.190
Q80-Q89 Other congenital malformations	0.808	0.192
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.804	0.196
H53.1 Subjective visual disturbances	0.804	0.196
Q50.4 Embryonic cyst of Fallopian tube	0.802	0.198
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.800	0.200
Q20-Q28 Congenital malformations of the circulatory system	0.800	0.200
Y43.3 Other antineoplastic drugs	0.797	0.203
V10-V19 Pedal cyclist injured in transport accident	0.795	0.205
K70 Alcoholic liver disease	0.795	0.205
Y00-Y09 Assault	0.793	0.207
E14 Unspecified diabetes mellitus	0.793	0.207
G47.9 Sleep disorder, unspecified	0.791	0.209
Y44 Agents primarily affecting blood constituents	0.791	0.209
A65-A69 Other spirochaetal diseases	0.791	0.209
H93 Other disorders of ear, not elsewhere classified	0.791	0.209
Q76 Congenital malformations of spine and bony thorax	0.787	0.213
K51.2 Ulcerative (chronic) proctitis	0.787	0.213
H35 Other retinal disorders	0.786	0.214
E10.0 With coma	0.786	0.214
H70 Mastoiditis and related conditions	0.786	0.214
H65.2 Chronic serous otitis media	0.785	0.215
E11.2 With renal complications	0.784	0.216
W00-W19 Falls	0.780	0.220
H53.2 Diplopia	0.779	0.221
E27 Other disorders of adrenal gland	0.776	0.224
K76.8 Other specified diseases of liver	0.776	0.224
G70-G73 Diseases of myoneural junction and muscle	0.774	0.226
H71 Cholesteatoma of middle ear	0.773	0.227
D84 Other immunodeficiencies	0.772	0.228
Y41 Other systemic anti-infectives and antiparasitics	0.772	0.228
E11.0 With coma	0.766	0.234
K51.8 Other ulcerative colitis	0.764	0.236
K74.3 Primary biliary cirrhosis	0.763	0.237
B49 Unspecified mycosis	0.762	0.237
E10.1 With ketoacidosis	0.756	0.244
D86.8 Sarcoidosis of other and combined sites	0.756	0.244
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.755	0.245
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.753	0.247
D55-D59 Haemolytic anaemias	0.752	0.248
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.752	0.248
H65.3 Chronic mucoid otitis media	0.751	0.249
H60-H62 Diseases of external ear	0.750	0.250
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.750	0.250
W20-W49 Exposure to inanimate mechanical forces	0.749	0.251
Q53 Undescended testicle	0.749	0.251
E28 Ovarian dysfunction	0.748	0.252
D50-D53 Nutritional anaemias	0.748	0.252
Y60-Y69 Misadventures to patients during surgical and medical care	0.748	0.252
F43.0 Acute stress reaction	0.747	0.253
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.746	0.254
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.746	0.254
Q51 Congenital malformations of uterus and cervix	0.745	0.255
Q82 Other congenital malformations of skin	0.745	0.255
K70.4 Alcoholic hepatic failure	0.744	0.255
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.740	0.260
Chapter IX Diseases of the circulatory system	0.739	0.261
G40.8 Other epilepsy	0.739	0.261
E11.6 With other specified complications	0.737	0.263
B18 Chronic viral hepatitis	0.736	0.264
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.736	0.264
E11.1 With ketoacidosis	0.736	0.264
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.734	0.266
B20-B24 Human immunodeficiency virus [HIV] disease	0.732	0.268
Y10-Y34 Event of undetermined intent	0.730	0.270
K76.9 Liver disease, unspecified	0.729	0.271
X10-X19 Contact with heat and hot substances	0.727	0.273
E40-E46 Malnutrition	0.727	0.273
Y58 Bacterial vaccines	0.726	0.274
E24 Cushing's syndrome	0.725	0.274
E34 Other endocrine disorders	0.724	0.276
E21.0 Primary hyperparathyroidism	0.724	0.276
H66.4 Suppurative otitis media, unspecified	0.722	0.278
F80-F89 Disorders of psychological development	0.722	0.278
D86.0 Sarcoidosis of lung	0.722	0.278
F99-F99 Unspecified mental disorder	0.722	0.278
H55 Nystagmus and other irregular eye movements	0.720	0.280
Y43.4 Immunosuppressive agents	0.719	0.280
D86.9 Sarcoidosis, unspecified	0.719	0.281
G41 Status epilepticus	0.718	0.282
E11.7 With multiple complications	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
E10.7 With multiple complications	0.717	0.283
D80 Immunodeficiency with predominantly antibody defects	0.717	0.283
B37.2 Candidiasis of skin and nail	0.715	0.285
B17 Other acute viral hepatitis	0.715	0.285
Chapter XVI Certain conditions originating in the perinatal period	0.714	0.286
A15-A19 Tuberculosis	0.713	0.287
F61 Mixed and other personality disorders	0.711	0.289
E11.5 With peripheral circulatory complications	0.709	0.291
X50-X57 Overexertion, travel and privation	0.708	0.291
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.707	0.293
H66.9 Otitis media, unspecified	0.707	0.293
Q24 Other congenital malformations of heart	0.707	0.293
B85-B89 Pediculosis, acariasis and other infestations	0.706	0.294
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.706	0.294
A75-A79 Rickettsioses	0.706	0.294
A70-A74 Other diseases caused by chlamydiae	0.706	0.294
A20-A28 Certain zoonotic bacterial diseases	0.706	0.294
G40.7 Petit mal, unspecified, without grand mal seizures	0.706	0.294
I95-I99 Other and unspecified disorders of the circulatory system	0.705	0.295
B48 Other mycoses, not elsewhere classified	0.704	0.296
B47 Mycetoma	0.704	0.296
B46 Zygomycosis	0.704	0.296
B45 Cryptococcosis	0.704	0.296
B43 Chromomycosis and phaeomycotic abscess	0.704	0.296
B42 Sporotrichosis	0.704	0.296
B41 Paracoccidioidomycosis	0.704	0.296
B40 Blastomycosis	0.704	0.296
B39 Histoplasmosis	0.704	0.296
B38 Coccidioidomycosis	0.704	0.296
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.703	0.297
V95-V97 Air and space transport accidents	0.703	0.297
Q82.8 Other specified congenital malformations of skin	0.702	0.297
B37.7 Candidal septicaemia	0.702	0.298
B37.6 Candidal endocarditis	0.702	0.298
B37.5 Candidal meningitis	0.702	0.298
D89.9 Disorder involving the immune mechanism, unspecified	0.702	0.298
B36 Other superficial mycoses	0.702	0.298
I98 Other disorders of circulatory system in diseases classified elsewhere	0.699	0.301
D86.1 Sarcoidosis of lymph nodes	0.699	0.301
H72.9 Perforation of tympanic membrane, unspecified	0.697	0.303
G72 Other myopathies	0.697	0.303
I98.2 Oesophageal varices in diseases classified elsewhere	0.697	0.303
Q23 Congenital malformations of aortic and mitral valves	0.696	0.304
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.695	0.305
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.694	0.306
Q35-Q37 Cleft lip and cleft palate	0.694	0.306
Q30-Q34 Congenital malformations of the respiratory system	0.694	0.306
B34 Viral infection of unspecified site	0.694	0.306
E23.0 Hypopituitarism	0.693	0.307
B99 Other and unspecified infectious diseases	0.693	0.307
Q78 Other osteochondrodysplasias	0.693	0.307
K73 Chronic hepatitis, not elsewhere classified	0.692	0.307
K76.5 Hepatic veno-occlusive disease	0.692	0.308
K76.4 Peliosis hepatis	0.692	0.308
K76.3 Infarction of liver	0.692	0.308
K76.2 Central haemorrhagic necrosis of liver	0.692	0.308
K76.1 Chronic passive congestion of liver	0.692	0.308
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.692	0.308
H68 Eustachian salpingitis and obstruction	0.692	0.308
H67 Otitis media in diseases classified elsewhere	0.692	0.308
Y40.8 Other systemic antibiotics	0.691	0.309
K51.9 Ulcerative colitis, unspecified	0.691	0.309
V01-V09 Pedestrian injured in transport accident	0.691	0.309
I10-I15 Hypertensive diseases	0.690	0.310
K77 Liver disorders in diseases classified elsewhere	0.689	0.311
K71 Toxic liver disease	0.689	0.311
B37.4 Candidiasis of other urogenital sites	0.689	0.311
Y44.2 Anticoagulants	0.686	0.314
F51 Nonorganic sleep disorders	0.686	0.314
Y35-Y36 Legal intervention and operations of war	0.686	0.314
X85-X99 Assault	0.686	0.314
X30-X39 Exposure to forces of nature	0.686	0.314
X00-X09 Exposure to smoke, fire and flames	0.686	0.314
W75-W84 Other accidental threats to breathing	0.686	0.314
W65-W74 Accidental drowning and submersion	0.686	0.314
V98-V99 Other and unspecified transport accidents	0.686	0.314
V90-V94 Water transport accidents	0.686	0.314
V70-V79 Bus occupant injured in transport accident	0.686	0.314
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.686	0.314
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.686	0.314
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.686	0.314
Q76.0 Spina bifida occulta	0.685	0.314
K74.5 Biliary cirrhosis, unspecified	0.682	0.318
I11 Hypertensive heart disease	0.682	0.318
F44 Dissociative [conversion] disorders	0.681	0.319
X58-X59 Accidental exposure to other and unspecified factors	0.679	0.321
K72 Hepatic failure, not elsewhere classified	0.678	0.322
H72.1 Attic perforation of tympanic membrane	0.677	0.323
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.676	0.324
I11.9 Hypertensive heart disease without (congestive) heart failure	0.676	0.324
B18.2 Chronic viral hepatitis C	0.676	0.324
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.676	0.324
B25 Cytomegaloviral disease	0.675	0.325
B35 Dermatophytosis	0.675	0.325
D68 Other coagulation defects	0.675	0.325
D83 Common variable immunodeficiency	0.674	0.325
D82 Immunodeficiency associated with other major defects	0.674	0.325
D81 Combined immunodeficiencies	0.674	0.325
H35.8 Other specified retinal disorders	0.674	0.326
G47.8 Other sleep disorders	0.671	0.329
Q55 Other congenital malformations of male genital organs	0.670	0.330
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.670	0.330
E35 Disorders of endocrine glands in diseases classified elsewhere	0.669	0.330
E32 Diseases of thymus	0.669	0.330
E31 Polyglandular dysfunction	0.669	0.330
E30 Disorders of puberty, not elsewhere classified	0.669	0.330
E25 Adrenogenital disorders	0.669	0.330
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.668	0.332
H65.1 Other acute nonsuppurative otitis media	0.668	0.332
D51 Vitamin B12 deficiency anaemia	0.666	0.334
Y40.5 Aminoglycosides	0.666	0.334
Y07 Other maltreatment syndromes	0.666	0.334
Y40.3 Macrolides	0.665	0.335
K74.4 Secondary biliary cirrhosis	0.665	0.335
K74.2 Hepatic fibrosis with hepatic sclerosis	0.665	0.335
K74.1 Hepatic sclerosis	0.665	0.335
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.664	0.336
H10-H13 Disorders of conjunctiva	0.664	0.336
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.663	0.336
K75 Other inflammatory liver diseases	0.664	0.336
Y59 Other and unspecified vaccines and biological substances	0.661	0.339
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.661	0.339
Y50 Central nervous system stimulants, not elsewhere classified	0.661	0.339
Y47 Sedatives, hypnotics and antianxiety drugs	0.661	0.339
H53.6 Night blindness	0.660	0.339
H53.5 Colour vision deficiencies	0.660	0.339
H53.3 Other disorders of binocular vision	0.660	0.339
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.660	0.340
H93.1 Tinnitus	0.659	0.341
Q56 Indeterminate sex and pseudohermaphroditism	0.659	0.341
Q52 Other congenital malformations of female genitalia	0.659	0.341
E27.2 Addisonian crisis	0.659	0.341
H70.9 Mastoiditis, unspecified	0.657	0.343
F70-F79 Mental retardation	0.657	0.343
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.656	0.343
H53.4 Visual field defects	0.656	0.344
H57 Other disorders of eye and adnexa	0.655	0.345
W60 Contact with plant thorns and spines and sharp leaves	0.655	0.345
K70.3 Alcoholic cirrhosis of liver	0.655	0.345
F64 Gender identity disorders	0.655	0.345
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.655	0.345
V20-V29 Motorcycle rider injured in transport accident	0.655	0.345
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.655	0.345
B07 Viral warts	0.654	0.346
H94 Other disorders of ear in diseases classified elsewhere	0.653	0.346
E14.1 With ketoacidosis	0.653	0.347
A69 Other spirochaetal infections	0.651	0.349
G20-G26 Extrapyramidal and movement disorders	0.651	0.349
H73 Other disorders of tympanic membrane	0.650	0.350
G44 Other headache syndromes	0.650	0.350
K51.0 Ulcerative (chronic) enterocolitis	0.650	0.350
D89.1 Cryoglobulinaemia	0.648	0.352
Y40.1 Cefalosporins and other -lactam antibiotics	0.648	0.352
Q00-Q07 Congenital malformations of the nervous system	0.646	0.354
D86.3 Sarcoidosis of skin	0.644	0.356
H93.9 Disorder of ear, unspecified	0.644	0.356
Y40.0 Penicillins	0.644	0.356
E10.4 With neurological complications	0.642	0.358
Y53 Agents primarily affecting the gastro-intestinal system	0.642	0.358
Y45.1 Salicylates	0.642	0.358
H35.9 Retinal disorder, unspecified	0.642	0.358
F43.8 Other reactions to severe stress	0.642	0.358
H35.7 Separation of retinal layers	0.641	0.359
H30 Chorioretinal inflammation	0.641	0.359
H65.0 Acute serous otitis media	0.641	0.359
B95-B98 Bacterial, viral and other infectious agents	0.640	0.360
H32 Chorioretinal disorders in diseases classified elsewhere	0.639	0.360
Y49 Psychotropic drugs, not elsewhere classified	0.639	0.361
Q24.8 Other specified congenital malformations of heart	0.639	0.361
F50 Eating disorders	0.639	0.361
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.639	0.361
E10.6 With other specified complications	0.638	0.362
F23 Acute and transient psychotic disorders	0.637	0.363
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.636	0.364
E23.1 Drug-induced hypopituitarism	0.636	0.364
E23.7 Disorder of pituitary gland, unspecified	0.636	0.364
H66.2 Chronic atticoantral suppurative otitis media	0.636	0.364
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.635	0.365
A50-A64 Infections with a predominantly sexual mode of transmission	0.635	0.365
A00-A09 Intestinal infectious diseases	0.634	0.366
Y51 Drugs primarily affecting the autonomic nervous system	0.633	0.366
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.632	0.368
F69 Unspecified disorder of adult personality and behaviour	0.632	0.368
G00-G09 Inflammatory diseases of the central nervous system	0.631	0.369
E14.9 Without complications	0.631	0.369
V80-V89 Other land transport accidents	0.631	0.369
H36.8 Other retinal disorders in diseases classified elsewhere	0.630	0.370
H35.3 Degeneration of macula and posterior pole	0.630	0.370
E11.4 With neurological complications	0.630	0.370
K74.0 Hepatic fibrosis	0.628	0.372
D84.8 Other specified immunodeficiencies	0.628	0.372
Q53.1 Undescended testicle, unilateral	0.627	0.372
Y40.9 Systemic antibiotic, unspecified	0.627	0.372
H53.9 Visual disturbance, unspecified	0.627	0.373
W29 Contact with other powered hand tools and household machinery	0.627	0.373
B00 Herpesviral [herpes simplex] infections	0.627	0.373
F43.9 Reaction to severe stress, unspecified	0.627	0.373
I05-I09 Chronic rheumatic heart diseases	0.627	0.373
H46-H48 Disorders of optic nerve and visual pathways	0.626	0.374
H66.3 Other chronic suppurative otitis media	0.625	0.375
W11 Fall on and from ladder	0.625	0.375
V17 Pedal cyclist injured in collision with fixed or stationary object	0.625	0.375
H61 Other disorders of external ear	0.623	0.377
D68.2 Hereditary deficiency of other clotting factors	0.622	0.378
K50 Crohn's disease [regional enteritis]	0.622	0.378
B17.1 Acute hepatitis C	0.622	0.378
Q23.1 Congenital insufficiency of aortic valve	0.621	0.379
H92.2 Otorrhagia	0.621	0.379
X40-X49 Accidental poisoning by and exposure to noxious substances	0.619	0.381
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.618	0.382
Q75 Other congenital malformations of skull and face bones	0.618	0.382
Q74 Other congenital malformations of limb(s)	0.618	0.382
Q73 Reduction defects of unspecified limb	0.618	0.382
Q72 Reduction defects of lower limb	0.618	0.382
Q71 Reduction defects of upper limb	0.618	0.382
Q70 Syndactyly	0.618	0.382
Q69 Polydactyly	0.618	0.382
Q68 Other congenital musculoskeletal deformities	0.618	0.382
G46 Vascular syndromes of brain in cerebrovascular diseases	0.617	0.382
W18 Other fall on same level	0.616	0.384
Q65 Congenital deformities of hip	0.616	0.384
H54 Blindness and low vision	0.616	0.384
Y43.9 Primarily systemic agent, unspecified	0.615	0.385
Y43.8 Other primarily systemic agents, not elsewhere classified	0.615	0.385
Y43.6 Enzymes, not elsewhere classified	0.615	0.385
Y43.5 Acidifying and alkalising agents	0.615	0.385
Y43.2 Antineoplastic natural products	0.615	0.385
H66.0 Acute suppurative otitis media	0.613	0.387
W07 Fall involving chair	0.613	0.387
B34.8 Other viral infections of unspecified site	0.612	0.388
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.610	0.390
Q50.5 Embryonic cyst of broad ligament	0.610	0.390
Q50.3 Other congenital malformations of ovary	0.610	0.390
Q50.2 Congenital torsion of ovary	0.610	0.390
Q50.1 Developmental ovarian cyst	0.610	0.390
Q50.0 Congenital absence of ovary	0.610	0.390
K51.5 Mucosal proctocolitis	0.610	0.390
W13 Fall from, out of or through building or structure	0.610	0.390
G47.3 Sleep apnoea	0.610	0.390
V10 Pedal cyclist injured in collision with pedestrian or animal	0.609	0.391
Y46 Antiepileptics and anti-Parkinsonism drugs	0.609	0.391
Q51.3 Bicornate uterus	0.608	0.392
Q25 Congenital malformations of great arteries	0.608	0.392
Q66 Congenital deformities of feet	0.607	0.392
G41.9 Status epilepticus, unspecified	0.607	0.393
Y40.7 Antifungal antibiotics, systemically used	0.606	0.394
Y40.6 Rifamycins	0.606	0.394
Y40.4 Tetracyclines	0.606	0.394
Y40.2 Chloramphenicol group	0.606	0.394
W15 Fall from cliff	0.605	0.395
D58 Other hereditary haemolytic anaemias	0.605	0.395
W17 Other fall from one level to another	0.604	0.395
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.604	0.395
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.605	0.395
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.604	0.396
E13 Other specified diabetes mellitus	0.604	0.396
W44 Foreign body entering into or through eye or natural orifice	0.604	0.396
Q54 Hypospadias	0.602	0.398
Y91 Evidence of alcohol involvement determined by level of intoxication	0.602	0.398
G71 Primary disorders of muscles	0.602	0.398
G40.4 Other generalised epilepsy and epileptic syndromes	0.601	0.398
B44 Aspergillosis	0.601	0.399
Y04 Assault by bodily force	0.601	0.399
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.601	0.399
K65-K67 Diseases of peritoneum	0.601	0.399
X20-X29 Contact with venomous animals and plants	0.600	0.399
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.600	0.400
B33 Other viral diseases, not elsewhere classified	0.599	0.401
B30 Viral conjunctivitis	0.599	0.401
B26 Mumps	0.599	0.401
I85 Oesophageal varices	0.598	0.402
D84.1 Defects in the complement system	0.598	0.402
W51 Striking against or bumped into by another person	0.597	0.403
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.597	0.403
H65.4 Other chronic nonsuppurative otitis media	0.596	0.403
D53 Other nutritional anaemias	0.595	0.405
G72.0 Drug-induced myopathy	0.594	0.406
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.593	0.406
Y43.0 Antiallergic and antiemetic drugs	0.593	0.407
I85.9 Oesophageal varices without bleeding	0.593	0.407
Q12 Congenital lens malformations	0.593	0.407
E20 Hypoparathyroidism	0.593	0.407
F29 Unspecified nonorganic psychosis	0.592	0.408
H72.8 Other perforations of tympanic membrane	0.592	0.408
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.591	0.408
F68 Other disorders of adult personality and behaviour	0.591	0.409
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.591	0.409
F65 Disorders of sexual preference	0.591	0.409
F63 Habit and impulse disorders	0.591	0.409
F62 Enduring personality changes, not attributable to brain damage and disease	0.591	0.409
W45 Foreign body or object entering through skin	0.590	0.409
H35.4 Peripheral retinal degeneration	0.590	0.410
W64 Exposure to other and unspecified animate mechanical forces	0.590	0.410
W59 Bitten or crushed by other reptiles	0.590	0.410
W58 Bitten or struck by crocodile or alligator	0.590	0.410
W56 Contact with marine animal	0.590	0.410
W54 Bitten or struck by dog	0.590	0.410
W53 Bitten by rat	0.590	0.410
W52 Crushed, pushed and stepped on by crowd or human stampede	0.590	0.410
B65-B83 Helminthiases	0.590	0.410
B97 Viral agents as the cause of diseases classified to other chapters	0.590	0.410
B50-B64 Protozoal diseases	0.587	0.412
Y58.0 BCG vaccine	0.586	0.414
B16 Acute hepatitis B	0.586	0.414
D57 Sickle-cell disorders	0.586	0.414
E27.1 Primary adrenocortical insufficiency	0.585	0.415
A04 Other bacterial intestinal infections	0.584	0.415
W03 Other fall on same level due to collision with, or pushing by, another person	0.584	0.416
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.584	0.416
D89.3 Immune reconstitution syndrome	0.584	0.416
D89.0 Polyclonal hypergammaglobulinaemia	0.584	0.416
E28.3 Primary ovarian failure	0.584	0.416
G47.2 Disorders of the sleep-wake schedule	0.581	0.419
H66.1 Chronic tubotympanic suppurative otitis media	0.581	0.419
X60-X84 Intentional self-harm	0.581	0.419
H74 Other disorders of middle ear and mastoid	0.580	0.420
H61.3 Acquired stenosis of external ear canal	0.580	0.420
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.579	0.421
Q84 Other congenital malformations of integument	0.579	0.421
Q81 Epidermolysis bullosa	0.579	0.421
Q80 Congenital ichthyosis	0.579	0.421
B37.1 Pulmonary candidiasis	0.579	0.421
D70-D77 Other diseases of blood and blood-forming organs	0.578	0.422
E21.5 Disorder of parathyroid gland, unspecified	0.576	0.423
E21.4 Other specified disorders of parathyroid gland	0.576	0.423
E21.2 Other hyperparathyroidism	0.576	0.423
E28.2 Polycystic ovarian syndrome	0.576	0.424
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.575	0.425
F99 Mental disorder, not otherwise specified	0.575	0.425
Y07.0 By spouse or partner	0.575	0.425
A04.5 Campylobacter enteritis	0.575	0.425
W01 Fall on same level from slipping, tripping and stumbling	0.574	0.426
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.574	0.426
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.574	0.426
F55 Abuse of non-dependence-producing substances	0.574	0.426
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.574	0.426
Q26 Congenital malformations of great veins	0.574	0.426
Q22 Congenital malformations of pulmonary and tricuspid valves	0.574	0.426
Q20 Congenital malformations of cardiac chambers and connexions	0.574	0.426
D56 Thalassaemia	0.573	0.427
H35.2 Other proliferative retinopathy	0.572	0.428
H31 Other disorders of choroid	0.571	0.429
Q78.0 Osteogenesis imperfecta	0.571	0.429
Y45.0 Opioids and related analgesics	0.571	0.429

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations