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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2239525
log Bayes Factor = 79.8251
Chromosome 6   position 31,509,372  (GRCh37) Explore rs2239525 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
J45.9 Asthma, unspecified
0.000 0.001 0.999
E14.3 With ophthalmic complications
0.000 0.002 0.998
I10-I15 Hypertensive diseases
0.000 0.002 0.998
Chapter IX Diseases of the circulatory system
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
# Top node
0.000 0.003 0.997
K90 Intestinal malabsorption
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.005 0.995
Chapter XI Diseases of the digestive system
0.000 0.005 0.995
L40.5 Arthropathic psoriasis
0.000 0.007 0.993
K90-K93 Other diseases of the digestive system
0.000 0.007 0.993
E14.9 Without complications
0.000 0.008 0.992
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.008 0.991
K70-K77 Diseases of liver
0.000 0.011 0.989
E10.4 With neurological complications
0.000 0.011 0.989
G35-G37 Demyelinating diseases of the central nervous system
0.988 0.012 0.000
G37 Other demyelinating diseases of central nervous system
0.986 0.014 0.000
Chapter VIII Diseases of the ear and mastoid process
0.000 0.015 0.985
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.017 0.983
G37.9 Demyelinating disease of central nervous system, unspecified
0.981 0.019 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.020 0.980
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.022 0.978
H36.0 Diabetic retinopathy
0.000 0.023 0.977
H36 Retinal disorders in diseases classified elsewhere
0.000 0.025 0.975
E70-E90 Metabolic disorders
0.000 0.026 0.974
H30-H36 Disorders of choroid and retina
0.000 0.026 0.974
I24 Other acute ischaemic heart diseases
0.000 0.028 0.972
I22 Subsequent myocardial infarction
0.000 0.031 0.969
H35 Other retinal disorders
0.000 0.034 0.966
K74 Fibrosis and cirrhosis of liver
0.000 0.034 0.966
I25.5 Ischaemic cardiomyopathy
0.000 0.039 0.961
Chapter VII Diseases of the eye and adnexa
0.000 0.040 0.960
L43 Lichen planus
0.000 0.041 0.959
H35.8 Other specified retinal disorders
0.000 0.042 0.958
H60-H62 Diseases of external ear
0.000 0.042 0.958
I20 Angina pectoris
0.000 0.042 0.958
H65-H75 Diseases of middle ear and mastoid
0.000 0.042 0.958
K50-K52 Noninfective enteritis and colitis
0.000 0.047 0.953
E00-E07 Disorders of thyroid gland
0.000 0.047 0.953
I20.9 Angina pectoris, unspecified
0.000 0.048 0.952
K52 Other non-infective gastro-enteritis and colitis
0.000 0.051 0.949
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.054 0.946
E03 Other hypothyroidism
0.000 0.059 0.941
I24.8 Other forms of acute ischaemic heart disease
0.000 0.063 0.937
E03.9 Hypothyroidism, unspecified
0.000 0.064 0.936
H71 Cholesteatoma of middle ear
0.000 0.064 0.936
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.068 0.932
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.069 0.931
H66 Suppurative and unspecified otitis media
0.000 0.070 0.930
H66.3 Other chronic suppurative otitis media
0.000 0.077 0.923
E13 Other specified diabetes mellitus
0.000 0.080 0.920
L43.9 Lichen planus, unspecified
0.000 0.093 0.907
E78.8 Other disorders of lipoprotein metabolism
0.000 0.094 0.906
I25.2 Old myocardial infarction
0.000 0.095 0.905
K74.6 Other and unspecified cirrhosis of liver
0.000 0.095 0.905
E10.8 With unspecified complications
0.000 0.098 0.902
E10.5 With peripheral circulatory complications
0.000 0.103 0.897
H61 Other disorders of external ear
0.000 0.103 0.897
K75 Other inflammatory liver diseases
0.000 0.104 0.896
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.114 0.886
E16 Other disorders of pancreatic internal secretion
0.000 0.116 0.884
G37.8 Other specified demyelinating diseases of central nervous system
0.875 0.125 0.000
H60 Otitis externa
0.000 0.127 0.873
E10.2 With renal complications
0.000 0.128 0.872
K74.5 Biliary cirrhosis, unspecified
0.000 0.131 0.869
E13.9 Without complications
0.000 0.138 0.862
E10.0 With coma
0.000 0.141 0.859
L50-L54 Urticaria and erythema
0.000 0.141 0.858
E11.6 With other specified complications
0.000 0.142 0.858
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.143 0.857
E78.2 Mixed hyperlipidaemia
0.000 0.144 0.856
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.145 0.855
J45 Asthma
0.000 0.151 0.849
K75.4 Autoimmune hepatitis
0.000 0.153 0.847
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.155 0.845
K73 Chronic hepatitis, not elsewhere classified
0.000 0.156 0.844
E11.0 With coma
0.000 0.157 0.843
E16.2 Hypoglycaemia, unspecified
0.000 0.163 0.837
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.164 0.836
I11 Hypertensive heart disease
0.000 0.166 0.834
K76 Other diseases of liver
0.000 0.167 0.833
H35.2 Other proliferative retinopathy
0.000 0.172 0.828
K52.1 Toxic gastro-enteritis and colitis
0.000 0.175 0.825
E14.8 With unspecified complications
0.000 0.177 0.823
E11.3 With ophthalmic complications
0.000 0.183 0.817
L43.8 Other lichen planus
0.000 0.189 0.811
K72 Hepatic failure, not elsewhere classified
0.000 0.191 0.809
H61.1 Non-infective disorders of pinna
0.000 0.195 0.805
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.200 0.800
E11.1 With ketoacidosis
0.000 0.202 0.798
L40.1 Generalised pustular psoriasis
0.000 0.209 0.791
J40-J47 Chronic lower respiratory diseases
0.000 0.210 0.790
H61.3 Acquired stenosis of external ear canal
0.000 0.210 0.790
H53-H54 Visual disturbances and blindness
0.000 0.211 0.789
I15 Secondary hypertension
0.000 0.214 0.786
L40.8 Other psoriasis
0.000 0.218 0.782
E10.6 With other specified complications
0.000 0.219 0.781
L42 Pityriasis rosea
0.000 0.220 0.780
Chapter X Diseases of the respiratory system
0.000 0.220 0.780
H35.5 Hereditary retinal dystrophy
0.000 0.221 0.779
E74 Other disorders of carbohydrate metabolism
0.000 0.222 0.778
E14.6 With other specified complications
0.000 0.222 0.778
K76.9 Liver disease, unspecified
0.000 0.225 0.775
K74.3 Primary biliary cirrhosis
0.000 0.235 0.765
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.237 0.763
H35.7 Separation of retinal layers
0.000 0.241 0.759
H35.0 Background retinopathy and retinal vascular changes
0.000 0.243 0.757
E78.6 Lipoprotein deficiency
0.000 0.244 0.756
I23 Certain current complications following acute myocardial infarction
0.000 0.244 0.756
E14.1 With ketoacidosis
0.000 0.250 0.750
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.750 0.250 0.000
H60.3 Other infective otitis externa
0.000 0.252 0.748
K75.8 Other specified inflammatory liver diseases
0.000 0.253 0.747
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.255 0.745
J43 Emphysema
0.000 0.255 0.745
K90.8 Other intestinal malabsorption
0.000 0.258 0.742
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.259 0.741
L40.3 Pustulosis palmaris et plantaris
0.000 0.262 0.738
K73.9 Chronic hepatitis, unspecified
0.000 0.266 0.734
I25.3 Aneurysm of heart
0.000 0.273 0.727
E11.2 With renal complications
0.000 0.273 0.727
H61.9 Disorder of external ear, unspecified
0.000 0.274 0.726
I20.0 Unstable angina
0.000 0.275 0.725
E85 Amyloidosis
0.000 0.275 0.725
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.275 0.725
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.276 0.724
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.277 0.723
H43-H45 Disorders of vitreous body and globe
0.000 0.281 0.719
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.282 0.718
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
I13 Hypertensive heart and renal disease
0.000 0.284 0.716
I00-I02 Acute rheumatic fever
0.000 0.284 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.285 0.715
L52 Erythema nodosum
0.000 0.285 0.715
H35.6 Retinal haemorrhage
0.000 0.285 0.715
K90.3 Pancreatic steatorrhoea
0.000 0.286 0.714
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.286 0.714
K90.1 Tropical sprue
0.000 0.286 0.714
E16.1 Other hypoglycaemia
0.000 0.287 0.713
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.288 0.712
K83 Other diseases of biliary tract
0.000 0.288 0.712
L10-L14 Bullous disorders
0.000 0.288 0.712
H31 Other disorders of choroid
0.000 0.290 0.710
K77 Liver disorders in diseases classified elsewhere
0.000 0.291 0.709
K86 Other diseases of pancreas
0.000 0.292 0.708
H61.2 Impacted cerumen
0.000 0.292 0.708
E14.5 With peripheral circulatory complications
0.000 0.292 0.708
G36 Other acute disseminated demyelination
0.707 0.293 0.000
H54 Blindness and low vision
0.000 0.293 0.707
H74 Other disorders of middle ear and mastoid
0.000 0.293 0.707
G37.5 Concentric sclerosis [Balo]
0.707 0.293 0.000
G37.4 Subacute necrotising myelitis
0.707 0.293 0.000
G37.2 Central pontine myelinolysis
0.707 0.293 0.000
G37.1 Central demyelination of corpus callosum
0.707 0.293 0.000
G37.0 Diffuse sclerosis
0.707 0.293 0.000
E14.4 With neurological complications
0.000 0.294 0.706
K71 Toxic liver disease
0.000 0.295 0.705
K83.0 Cholangitis
0.000 0.295 0.705
E79 Disorders of purine and pyrimidine metabolism
0.000 0.299 0.701
E78.3 Hyperchylomicronaemia
0.000 0.299 0.701
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.301 0.699
E77 Disorders of glycoprotein metabolism
0.000 0.301 0.698
E76 Disorders of glycosaminoglycan metabolism
0.000 0.301 0.698
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.301 0.698
E70 Disorders of aromatic amino-acid metabolism
0.000 0.301 0.698
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.301 0.698
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.302 0.698
J43.9 Emphysema, unspecified
0.000 0.303 0.697
L50 Urticaria
0.000 0.305 0.695
H35.1 Retinopathy of prematurity
0.000 0.307 0.693
H54.9 Unspecified visual impairment (binocular)
0.000 0.308 0.692
K74.4 Secondary biliary cirrhosis
0.000 0.308 0.692
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.308 0.692
K74.1 Hepatic sclerosis
0.000 0.308 0.692
K76.8 Other specified diseases of liver
0.000 0.308 0.692
H66.4 Suppurative otitis media, unspecified
0.000 0.309 0.691
E88 Other metabolic disorders
0.000 0.311 0.689
H34 Retinal vascular occlusions
0.000 0.311 0.689
L43.3 Subacute (active) lichen planus
0.000 0.312 0.688
L43.2 Lichenoid drug reaction
0.000 0.312 0.688
L43.1 Bullous lichen planus
0.000 0.312 0.688
L43.0 Hypertrophic lichen planus
0.000 0.312 0.688
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.313 0.687
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.313 0.687
H68 Eustachian salpingitis and obstruction
0.000 0.313 0.687
H67 Otitis media in diseases classified elsewhere
0.000 0.313 0.687
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.317 0.683
E00 Congenital iodine-deficiency syndrome
0.000 0.317 0.683
I25.4 Coronary artery aneurysm
0.000 0.317 0.682
H60.5 Acute otitis externa, non-infective
0.000 0.318 0.682
H70 Mastoiditis and related conditions
0.000 0.318 0.682
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.319 0.681
E05.9 Thyrotoxicosis, unspecified
0.000 0.321 0.679
K72.9 Hepatic failure, unspecified
0.000 0.324 0.676
E03.5 Myxoedema coma
0.000 0.325 0.675
E03.4 Atrophy of thyroid (acquired)
0.000 0.325 0.675
E03.3 Postinfectious hypothyroidism
0.000 0.325 0.675
E03.1 Congenital hypothyroidism without goitre
0.000 0.325 0.675
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.325 0.675
K86.1 Other chronic pancreatitis
0.000 0.328 0.672
K74.0 Hepatic fibrosis
0.000 0.330 0.670
H30 Chorioretinal inflammation
0.000 0.330 0.669
E15 Nondiabetic hypoglycaemic coma
0.000 0.331 0.668
L51 Erythema multiforme
0.000 0.331 0.668
H60.0 Abscess of external ear
0.000 0.334 0.666
E72 Other disorders of amino-acid metabolism
0.000 0.335 0.665
E78.4 Other hyperlipidaemia
0.000 0.336 0.664
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.336 0.664
E78.1 Pure hyperglyceridaemia
0.000 0.338 0.662
H60.4 Cholesteatoma of external ear
0.000 0.339 0.661
E11.4 With neurological complications
0.000 0.339 0.661
H35.9 Retinal disorder, unspecified
0.000 0.339 0.661
E13.8 With unspecified complications
0.000 0.341 0.659
E13.7 With multiple complications
0.000 0.341 0.659
E13.6 With other specified complications
0.000 0.341 0.659
E13.5 With peripheral circulatory complications
0.000 0.341 0.659
E13.4 With neurological complications
0.000 0.341 0.659
E13.3 With ophthalmic complications
0.000 0.341 0.659
E13.2 With renal complications
0.000 0.341 0.659
E13.1 With ketoacidosis
0.000 0.341 0.659
E13.0 With coma
0.000 0.341 0.659
H35.4 Peripheral retinal degeneration
0.000 0.341 0.659
H66.0 Acute suppurative otitis media
0.000 0.343 0.657
E83.1 Disorders of iron metabolism
0.657 0.343 0.000
H90-H95 Other disorders of ear
0.000 0.345 0.655
E84 Cystic fibrosis
0.000 0.346 0.654
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.347 0.653
H60.8 Other otitis externa
0.000 0.347 0.653
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.347 0.653
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.352 0.648
K75.2 Nonspecific reactive hepatitis
0.000 0.357 0.642
K75.1 Phlebitis of portal vein
0.000 0.357 0.642
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.362 0.638
J60-J70 Lung diseases due to external agents
0.000 0.363 0.637
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.366 0.634
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.366 0.634
E16.4 Abnormal secretion of gastrin
0.000 0.366 0.634
E16.3 Increased secretion of glucagon
0.000 0.366 0.634
L40.0 Psoriasis vulgaris
0.000 0.368 0.632
J46 Status asthmaticus
0.000 0.370 0.630
H72 Perforation of tympanic membrane
0.000 0.370 0.630
E07 Other disorders of thyroid
0.000 0.372 0.628
H60.9 Otitis externa, unspecified
0.000 0.373 0.627
E06 Thyroiditis
0.000 0.373 0.627
K90.9 Intestinal malabsorption, unspecified
0.000 0.373 0.627
H60.2 Malignant otitis externa
0.000 0.374 0.626
E11.5 With peripheral circulatory complications
0.000 0.375 0.624
H60.1 Cellulitis of external ear
0.000 0.376 0.624
E40-E46 Malnutrition
0.000 0.377 0.623
E89.3 Postprocedural hypopituitarism
0.000 0.378 0.622
I22.8 Subsequent myocardial infarction of other sites
0.000 0.379 0.621
H43 Disorders of vitreous body
0.000 0.379 0.621
K86.2 Cyst of pancreas
0.000 0.381 0.619
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.382 0.617
L54 Erythema in diseases classified elsewhere
0.000 0.384 0.615
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.385 0.615
I24.1 Dressler's syndrome
0.000 0.391 0.609
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.391 0.609
J45.1 Nonallergic asthma
0.000 0.392 0.608
H74.4 Polyp of middle ear
0.000 0.394 0.606
E05.5 Thyroid crisis or storm
0.000 0.394 0.606
E05.4 Thyrotoxicosis factitia
0.000 0.394 0.606
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.394 0.606
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.394 0.606
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.395 0.605
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.395 0.605
I15.1 Hypertension secondary to other renal disorders
0.000 0.396 0.604
I12 Hypertensive renal disease
0.000 0.398 0.602
J42 Unspecified chronic bronchitis
0.000 0.398 0.601
H73 Other disorders of tympanic membrane
0.000 0.399 0.601
E88.2 Lipomatosis, not elsewhere classified
0.000 0.400 0.600
K76.5 Hepatic veno-occlusive disease
0.000 0.402 0.597
K76.4 Peliosis hepatis
0.000 0.402 0.597
K76.3 Infarction of liver
0.000 0.402 0.597
K76.2 Central haemorrhagic necrosis of liver
0.000 0.402 0.597
H55-H59 Other disorders of eye and adnexa
0.000 0.403 0.597
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.405 0.595
J43.2 Centrilobular emphysema
0.000 0.409 0.591
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.410 0.590
L13 Other bullous disorders
0.000 0.411 0.589
H90 Conductive and sensorineural hearing loss
0.000 0.414 0.586
K72.0 Acute and subacute hepatic failure
0.000 0.414 0.586
H54.7 Unspecified visual loss
0.000 0.415 0.585
K60.2 Anal fissure, unspecified
0.000 0.415 0.585
E85.9 Amyloidosis, unspecified
0.000 0.415 0.584
I15.9 Seconday hypertension, unspecified
0.000 0.416 0.584
J69 Pneumonitis due to solids and liquids
0.000 0.418 0.582
I15.0 Renovascular hypertension
0.000 0.418 0.582
I23.8 Other current complications following acute myocardial infarction
0.000 0.418 0.582
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.419 0.581
K72.1 Chronic hepatic failure
0.000 0.420 0.580
E50-E64 Other nutritional deficiencies
0.000 0.421 0.579
E78.5 Hyperlipidaemia, unspecified
0.000 0.422 0.578
K86.3 Pseudocyst of pancreas
0.000 0.423 0.577
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.424 0.576
K60 Fissure and fistula of anal and rectal regions
0.000 0.427 0.573
K55-K64 Other diseases of intestines
0.000 0.430 0.570
I15.8 Other secondary hypertension
0.000 0.436 0.564
I15.2 Hypertension secondary to endocrine disorders
0.000 0.436 0.564
E83 Disorders of mineral metabolism
0.529 0.438 0.033
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.440 0.560
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.442 0.558
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.442 0.558
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.442 0.558
E74.2 Disorders of galactose metabolism
0.000 0.442 0.558
E74.1 Disorders of fructose metabolism
0.000 0.442 0.558
E74.0 Glycogen storage disease
0.000 0.442 0.558
L50.9 Urticaria, unspecified
0.000 0.443 0.557
J41 Simple and mucopurulent chronic bronchitis
0.000 0.447 0.553
L53 Other erythematous conditions
0.000 0.448 0.552
K75.9 Inflammatory liver disease, unspecified
0.000 0.448 0.552
K75.0 Abscess of liver
0.000 0.450 0.550
J43.8 Other emphysema
0.000 0.451 0.549
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.452 0.547
J69.0 Pneumonitis due to food and vomit
0.000 0.453 0.547
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.453 0.547
K83.3 Fistula of bile duct
0.000 0.456 0.544
H61.8 Other specified disorders of external ear
0.000 0.457 0.543
H90.5 Sensorineural hearing loss, unspecified
0.000 0.457 0.543
E75.5 Other lipid storage disorders
0.000 0.458 0.542
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.458 0.542
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.458 0.542
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.458 0.542
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.458 0.542
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.458 0.542
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.458 0.542
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.458 0.542
H31.1 Choroidal degeneration
0.000 0.458 0.542
H31.0 Chorioretinal scars
0.000 0.459 0.541
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.459 0.541
E73 Lactose intolerance
0.000 0.460 0.540
H47.3 Other disorders of optic disk
0.000 0.461 0.539
J85 Abscess of lung and mediastinum
0.000 0.461 0.539
J86 Pyothorax
0.000 0.462 0.538
L50.0 Allergic urticaria
0.000 0.462 0.538
J45.8 Mixed asthma
0.000 0.463 0.537
H34.8 Other retinal vascular occlusions
0.000 0.464 0.536
K58 Irritable bowel syndrome
0.000 0.464 0.536
J43.1 Panlobular emphysema
0.000 0.466 0.534
J43.0 MacLeod's syndrome
0.000 0.466 0.534
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.469 0.531
H92 Otalgia and effusion of ear
0.000 0.471 0.529
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.473 0.527
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.474 0.526
E88.3 Tumour lysis syndrome
0.000 0.474 0.526
H43.2 Crystalline deposits in vitreous body
0.000 0.476 0.524
E85.3 Secondary systemic amyloidosis
0.000 0.480 0.520
H72.2 Other marginal perforations of tympanic membrane
0.000 0.480 0.520
E85.8 Other amyloidosis
0.000 0.480 0.520
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.480 0.520
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.480 0.520
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.480 0.520
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.481 0.519
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.481 0.519
E89.5 Postprocedural testicular hypofunction
0.000 0.481 0.519
E89.1 Postprocedural hypoinsulinaemia
0.000 0.481 0.519
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.481 0.519
E83.3 Disorders of phosphorus metabolism
0.514 0.481 0.005
E75.6 Lipid storage disorder, unspecified
0.000 0.482 0.518
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.482 0.518
E75.3 Sphingolipidosis, unspecified
0.000 0.482 0.518
E75.2 Other sphingolipidosis
0.000 0.482 0.518
E75.1 Other gangliosidosis
0.000 0.482 0.518
E75.0 GM2 gangliosidosis
0.000 0.482 0.518
H43.9 Disorder of vitreous body, unspecified
0.000 0.483 0.517
K52.3 Indeterminate colitis
0.000 0.484 0.516
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.484 0.516
K76.1 Chronic passive congestion of liver
0.000 0.484 0.516
H72.0 Central perforation of tympanic membrane
0.000 0.485 0.515
L51.1 Bullous erythema multiforme
0.000 0.485 0.515
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
H54.0 Blindness, both eyes
0.000 0.486 0.514
L41.9 Parapsoriasis, unspecified
0.000 0.486 0.513
L41.8 Other parapsoriasis
0.000 0.486 0.513
L41.5 Retiform parapsoriasis
0.000 0.486 0.513
L41.4 Large plaque parapsoriasis
0.000 0.486 0.513
L41.3 Small plaque parapsoriasis
0.000 0.486 0.513
L41.2 Lymphomatoid papulosis
0.000 0.486 0.513
L41.1 Pityriasis lichenoides chronica
0.000 0.486 0.513
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.486 0.513
L44.9 Papulosquamous disorder, unspecified
0.000 0.486 0.513
L44.8 Other specified papulosquamous disorders
0.000 0.486 0.513
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.486 0.513
L44.3 Lichen ruber moniliformis
0.000 0.486 0.513
L44.2 Lichen striatus
0.000 0.486 0.513
L44.1 Lichen nitidus
0.000 0.486 0.513
L44.0 Pityriasis rubra pilaris
0.000 0.486 0.513
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.487 0.513
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.487 0.513
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.487 0.513
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.487 0.513
I02 Rheumatic chorea
0.000 0.487 0.513
I01 Rheumatic fever with heart involvement
0.000 0.487 0.513
I00 Rheumatic fever without mention of heart involvement
0.000 0.487 0.513
P90-P96 Other disorders originating in the perinatal period
0.000 0.487 0.513
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.487 0.513
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.487 0.513
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.487 0.513
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.487 0.513
P35-P39 Infections specific to the perinatal period
0.000 0.487 0.513
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.487 0.513
P10-P15 Birth trauma
0.000 0.487 0.513
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.487 0.513
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.487 0.513
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.488 0.512
H70.1 Chronic mastoiditis
0.000 0.489 0.511
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.489 0.511
K93.1 Megacolon in Chagas' disease
0.000 0.489 0.511
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.489 0.511
K83.5 Biliary cyst
0.000 0.489 0.510
K83.2 Perforation of bile duct
0.000 0.489 0.510
L10 Pemphigus
0.000 0.490 0.510
L14 Bullous disorders in diseases classified elsewhere
0.000 0.490 0.510
H31.9 Disorder of choroid, unspecified
0.000 0.491 0.509
H31.4 Choroidal detachment
0.000 0.491 0.509
H31.2 Hereditary choroidal dystrophy
0.000 0.491 0.509
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.491 0.508
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.491 0.508
G36.9 Acute disseminated demyelination, unspecified
0.507 0.493 0.000
G36.8 Other specified acute disseminated demyelination
0.507 0.493 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.507 0.493 0.000
H54.3 Unqualified visual loss, both eyes
0.000 0.493 0.507
H54.2 Low vision, both eyes
0.000 0.493 0.507
J45.0 Predominantly allergic asthma
0.000 0.493 0.507
L50.1 Idiopathic urticaria
0.000 0.494 0.506
G36.0 Neuromyelitis optica [Devic]
0.506 0.494 0.000
K71.9 Toxic liver disease, unspecified
0.000 0.494 0.506
K71.8 Toxic liver disease with other disorders of liver
0.000 0.494 0.506
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.494 0.506
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.494 0.506
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.494 0.506
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.494 0.506
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.494 0.506
K71.2 Toxic liver disease with acute hepatitis
0.000 0.494 0.506
K71.0 Toxic liver disease with cholestasis
0.000 0.494 0.506
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.494 0.505
H47.2 Optic atrophy
0.000 0.495 0.505
K83.4 Spasm of sphincter of Oddi
0.000 0.495 0.505
K81 Cholecystitis
0.000 0.496 0.504
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.497 0.503
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.497 0.503
E79.1 Lesch-Nyhan syndrome
0.000 0.497 0.503
H55 Nystagmus and other irregular eye movements
0.000 0.497 0.503
H31.3 Choroidal haemorrhage and rupture
0.000 0.498 0.502
K60.0 Acute anal fissure
0.000 0.498 0.502
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.498 0.501
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.499 0.501
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.499 0.501
E70.3 Albinism
0.000 0.499 0.501
E70.2 Disorders of tyrosine metabolism
0.000 0.499 0.501
E70.1 Other hyperphenylalaninaemias
0.000 0.499 0.501
E70.0 Classical phenylketonuria
0.000 0.499 0.501
E71.3 Disorders of fatty-acid metabolism
0.000 0.499 0.501
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.499 0.501
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.499 0.501
E71.0 Maple-syrup-urine disease
0.000 0.499 0.501
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.499 0.501
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.499 0.501
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.499 0.501
E76.2 Other mucopolysaccharidoses
0.000 0.499 0.501
E76.1 Mucopolysaccharidosis, type II
0.000 0.499 0.501
E76.0 Mucopolysaccharidosis, type I
0.000 0.499 0.501

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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