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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2245514
log Bayes Factor = 25.077
Chromosome 6   position 30,432,455  (GRCh37) Explore rs2245514 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.001 0.999
E10.9 Without complications
0.000 0.015 0.985
E10 Insulin-dependent diabetes mellitus
0.000 0.025 0.975
G35 Multiple sclerosis
0.968 0.032 0.000
G20-G26 Extrapyramidal and movement disorders
0.961 0.039 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.960 0.040 0.000
G24 Dystonia
0.957 0.043 0.000
E10.3 With ophthalmic complications
0.000 0.044 0.956
G25 Other extrapyramidal and movement disorders
0.954 0.046 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.945 0.055 0.000
Chapter VI Diseases of the nervous system
0.945 0.055 0.000
G24.8 Other dystonia
0.894 0.106 0.000
E10.2 With renal complications
0.000 0.127 0.873
G24.9 Dystonia, unspecified
0.868 0.132 0.000
E10.1 With ketoacidosis
0.000 0.151 0.849
G37 Other demyelinating diseases of central nervous system
0.847 0.153 0.000
G24.0 Drug-induced dystonia
0.818 0.182 0.000
G25.5 Other chorea
0.806 0.194 0.000
G24.3 Spasmodic torticollis
0.801 0.199 0.000
E10.4 With neurological complications
0.000 0.201 0.799
G24.5 Blepharospasm
0.793 0.207 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.785 0.215 0.000
K90 Intestinal malabsorption
0.000 0.223 0.777
G25.1 Drug-induced tremor
0.774 0.226 0.000
G90-G99 Other disorders of the nervous system
0.765 0.235 0.000
G20 Parkinson's disease
0.764 0.236 0.000
E10.0 With coma
0.000 0.244 0.756
G40-G47 Episodic and paroxysmal disorders
0.751 0.249 0.000
G21 Secondary Parkinsonism
0.720 0.280 0.000
G30-G32 Other degenerative diseases of the nervous system
0.714 0.286 0.000
G25.3 Myoclonus
0.714 0.286 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.713 0.287 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.297 0.703
G23 Other degenerative diseases of basal ganglia
0.699 0.301 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.306 0.694
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.689 0.311 0.000
G22 Parkinsonism in diseases classified elsewhere
0.689 0.311 0.000
G36 Other acute disseminated demyelination
0.688 0.312 0.000
G24.4 Idiopathic orofacial dystonia
0.686 0.314 0.000
G24.2 Idiopathic nonfamilial dystonia
0.686 0.314 0.000
G24.1 Idiopathic familial dystonia
0.686 0.314 0.000
G40 Epilepsy
0.685 0.315 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.684 0.316 0.000
G25.4 Drug-induced chorea
0.684 0.316 0.000
G25.2 Other specified forms of tremor
0.684 0.316 0.000
E10.8 With unspecified complications
0.000 0.316 0.684
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.318 0.682
G93 Other disorders of brain
0.680 0.320 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.325 0.675
G93.4 Encephalopathy, unspecified
0.671 0.329 0.000
G96 Other disorders of central nervous system
0.669 0.331 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.665 0.335 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.662 0.338 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.348 0.652
G41 Status epilepticus
0.648 0.352 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.644 0.356 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.636 0.364 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.367 0.633
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.368 0.632
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.369 0.631
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.622 0.378 0.000
G46.7 Other lacunar syndromes
0.613 0.387 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.387 0.613
G37.5 Concentric sclerosis [Balo]
0.607 0.393 0.000
G37.4 Subacute necrotising myelitis
0.607 0.393 0.000
G37.2 Central pontine myelinolysis
0.607 0.393 0.000
G37.1 Central demyelination of corpus callosum
0.607 0.393 0.000
G37.0 Diffuse sclerosis
0.607 0.393 0.000
E10.6 With other specified complications
0.000 0.395 0.605
E10.7 With multiple complications
0.000 0.395 0.605
G00-G09 Inflammatory diseases of the central nervous system
0.604 0.396 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.603 0.397 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.595 0.405 0.000
K90.8 Other intestinal malabsorption
0.000 0.406 0.594
G93.1 Anoxic brain damage, not elsewhere classified
0.592 0.408 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.588 0.412 0.000
G96.0 Cerebrospinal fluid leak
0.585 0.415 0.000
G43 Migraine
0.583 0.417 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.420 0.580
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.580 0.420 0.000
L40.9 Psoriasis, unspecified
0.576 0.424 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.576 0.424 0.000
E10.5 With peripheral circulatory complications
0.000 0.428 0.572
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.568 0.432 0.000
G41.9 Status epilepticus, unspecified
0.561 0.439 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.443 0.557
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.443 0.557
K90.1 Tropical sprue
0.000 0.443 0.557
G92 Toxic encephalopathy
0.548 0.451 0.000
G97.8 Other postprocedural disorders of nervous system
0.547 0.453 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.546 0.454 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.546 0.454 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.469 0.531
G31.2 Degeneration of nervous system due to alcohol
0.530 0.470 0.000
G25.0 Essential tremor
0.529 0.471 0.000
E10-E14 Diabetes mellitus
0.000 0.472 0.528
G93.8 Other specified disorders of brain
0.527 0.473 0.000
G40.5 Special epileptic syndromes
0.526 0.473 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.477 0.523
G40.9 Epilepsy, unspecified
0.522 0.478 0.000
G21.9 Secondary Parkinsonism, unspecified
0.516 0.484 0.000
G21.8 Other secondary Parkinsonism
0.516 0.484 0.000
G21.4 Vascular parkinsonism
0.516 0.484 0.000
G21.3 Postencephalitic Parkinsonism
0.516 0.484 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.516 0.484 0.000
G21.0 Malignant neuroleptic syndrome
0.516 0.484 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.512 0.488 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.511 0.488 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.511 0.489 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.511 0.489 0.000
G43.8 Other migraine
0.511 0.489 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.508 0.492 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.503 0.497 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.501 0.498 0.000
G23.3 Multiple system atrophy, cerebellar type
0.501 0.498 0.000
G23.2 Striatonigral degeneration
0.501 0.498 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.501 0.498 0.000
G23.0 Hallervorden-Spatz disease
0.501 0.498 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.493 0.506 0.000
G36.9 Acute disseminated demyelination, unspecified
0.493 0.506 0.000
G36.8 Other specified acute disseminated demyelination
0.493 0.506 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.493 0.506 0.000
G36.0 Neuromyelitis optica [Devic]
0.493 0.506 0.000
G41.0 Grand mal status epilepticus
0.493 0.507 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.491 0.509 0.000
G93.7 Reye's syndrome
0.487 0.513 0.000
L40 Psoriasis
0.482 0.518 0.000
G96.9 Disorder of central nervous system, unspecified
0.480 0.520 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.477 0.523 0.000
G46.6 Pure sensory lacunar syndrome
0.477 0.523 0.000
G46.5 Pure motor lacunar syndrome
0.477 0.523 0.000
G46.3 Brain stem stroke syndrome
0.477 0.523 0.000
G46.2 Posterior cerebral artery syndrome
0.477 0.523 0.000
G46.1 Anterior cerebral artery syndrome
0.477 0.523 0.000
G46.0 Middle cerebral artery syndrome
0.477 0.523 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.474 0.526 0.000
G93.6 Cerebral oedema
0.469 0.531 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.467 0.533 0.000
G30 Alzheimer's disease
0.466 0.534 0.000
G93.3 Postviral fatigue syndrome
0.465 0.535 0.000
G41.8 Other status epilepticus
0.465 0.535 0.000
G41.2 Complex partial status epilepticus
0.465 0.535 0.000
G41.1 Petit mal status epilepticus
0.465 0.535 0.000
G40.8 Other epilepsy
0.463 0.537 0.000
E13 Other specified diabetes mellitus
0.000 0.543 0.456
G11 Hereditary ataxia
0.454 0.545 0.000
G03 Meningitis due to other and unspecified causes
0.452 0.547 0.000
L40.5 Arthropathic psoriasis
0.449 0.551 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.447 0.553 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.446 0.554 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.446 0.554 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.443 0.557 0.000
G46.4 Cerebellar stroke syndrome
0.441 0.558 0.000
G43.0 Migraine without aura [common migraine]
0.438 0.562 0.000
G93.5 Compression of brain
0.433 0.567 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.433 0.567 0.000
G96.8 Other specified disorders of central nervous system
0.431 0.568 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.431 0.569 0.000
G95 Other diseases of spinal cord
0.430 0.570 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.429 0.571 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.427 0.573 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.426 0.574 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.422 0.578 0.000
G14 Postpolio syndrome
0.422 0.578 0.000
G44 Other headache syndromes
0.422 0.578 0.000
G43.3 Complicated migraine
0.418 0.582 0.000
G43.2 Status migrainosus
0.418 0.582 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.416 0.584 0.000
G10 Huntington's disease
0.414 0.585 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.413 0.587 0.000
E13.9 Without complications
0.000 0.595 0.405
G31.0 Circumscribed brain atrophy
0.405 0.595 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.404 0.596 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.402 0.598 0.000
G43.1 Migraine with aura [classical migraine]
0.402 0.598 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.599 0.401
L40.3 Pustulosis palmaris et plantaris
0.397 0.602 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.394 0.606 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.392 0.608 0.000
G93.2 Benign intracranial hypertension
0.391 0.608 0.000
G06.2 Extradural and subdural abscess, unspecified
0.386 0.614 0.000
G00 Bacterial meningitis, not elsewhere classified
0.379 0.620 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.621 0.379
G30.8 Other Alzheimer's disease
0.373 0.627 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.367 0.633 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.367 0.633 0.000
E14 Unspecified diabetes mellitus
0.000 0.633 0.367
L40.8 Other psoriasis
0.367 0.633 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.364 0.635 0.000
G06.1 Intraspinal abscess and granuloma
0.365 0.635 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.364 0.636 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.361 0.639 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.361 0.639 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.361 0.639 0.000
G95.0 Syringomyelia and syringobulbia
0.359 0.641 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.354 0.646 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.652 0.348
G11.1 Early-onset cerebellar ataxia
0.346 0.654 0.000
L40.4 Guttate psoriasis
0.346 0.654 0.000
L40.2 Acrodermatitis continua
0.346 0.654 0.000
L40.1 Generalised pustular psoriasis
0.346 0.654 0.000
G03.9 Meningitis, unspecified
0.344 0.656 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.341 0.659 0.000
G11.4 Hereditary spastic paraplegia
0.340 0.659 0.000
G30.0 Alzheimer's disease with early onset
0.338 0.661 0.000
G30.1 Alzheimer's disease with late onset
0.334 0.665 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.666 0.334
E03 Other hypothyroidism
0.000 0.667 0.333
G70-G73 Diseases of myoneural junction and muscle
0.331 0.668 0.000
E00-E07 Disorders of thyroid gland
0.000 0.670 0.330
E13.8 With unspecified complications
0.000 0.672 0.327
E13.7 With multiple complications
0.000 0.672 0.327
E13.6 With other specified complications
0.000 0.672 0.327
E13.5 With peripheral circulatory complications
0.000 0.672 0.327
E13.4 With neurological complications
0.000 0.672 0.327
E13.3 With ophthalmic complications
0.000 0.672 0.327
E13.2 With renal complications
0.000 0.672 0.327
E13.1 With ketoacidosis
0.000 0.672 0.327
E13.0 With coma
0.000 0.672 0.327
G11.9 Hereditary ataxia, unspecified
0.326 0.674 0.000
G11.8 Other hereditary ataxias
0.326 0.674 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.326 0.674 0.000
G11.2 Late-onset cerebellar ataxia
0.326 0.674 0.000
G11.0 Congenital nonprogressive ataxia
0.326 0.674 0.000
G44.2 Tension-type headache
0.326 0.674 0.000
G03.8 Meningitis due to other specified causes
0.324 0.675 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.324 0.675 0.000
G03.1 Chronic meningitis
0.324 0.675 0.000
G03.0 Nonpyogenic meningitis
0.324 0.675 0.000
E14.3 With ophthalmic complications
0.000 0.685 0.315
G44.3 Chronic posttraumatic headache
0.310 0.690 0.000
G60 Hereditary and idiopathic neuropathy
0.308 0.692 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.305 0.694 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.305 0.694 0.000
G95.2 Cord compression, unspecified
0.305 0.695 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.305 0.695 0.000
G64 Other disorders of peripheral nervous system
0.303 0.697 0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.302 0.697 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.302 0.697 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.302 0.697 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.302 0.697 0.000
G44.1 Vascular headache, not elsewhere classified
0.302 0.698 0.000
G06.0 Intracranial abscess and granuloma
0.301 0.698 0.000
G82 Paraplegia and tetraplegia
0.296 0.704 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.296 0.704 0.000
G04.1 Tropical spastic paraplegia
0.296 0.704 0.000
G04.0 Acute disseminated encephalitis
0.296 0.704 0.000
G43.9 Migraine, unspecified
0.295 0.705 0.000
E07 Other disorders of thyroid
0.000 0.709 0.291
E14.8 With unspecified complications
0.000 0.711 0.289
G00.2 Streptococcal meningitis
0.288 0.712 0.000
G83 Other paralytic syndromes
0.287 0.713 0.000
E14.1 With ketoacidosis
0.000 0.715 0.285
E50-E64 Other nutritional deficiencies
0.000 0.715 0.285
G12 Spinal muscular atrophy and related syndromes
0.284 0.716 0.001
G00.8 Other bacterial meningitis
0.272 0.728 0.000
G00.3 Staphylococcal meningitis
0.272 0.728 0.000
G00.0 Haemophilus meningitis
0.272 0.728 0.000
E12.9 Without complications
0.000 0.728 0.272
E12.8 With unspecified complications
0.000 0.728 0.272
E12.7 With multiple complications
0.000 0.728 0.272
E12.6 With other specified complications
0.000 0.728 0.272
E12.5 With peripheral circulatory complications
0.000 0.728 0.272
E12.4 With neurological complications
0.000 0.728 0.272
E12.3 With ophthalmic complications
0.000 0.728 0.272
E12.2 With renal complications
0.000 0.728 0.272
E12.1 With ketoacidosis
0.000 0.728 0.272
E12.0 With coma
0.000 0.728 0.272
G82.1 Spastic paraplegia
0.270 0.730 0.000
G00.1 Pneumococcal meningitis
0.268 0.732 0.000
G94.1 Hydrocephalus in neoplastic disease
0.263 0.736 0.000
G95.8 Other specified diseases of spinal cord
0.264 0.736 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.736 0.264
E14.7 With multiple complications
0.000 0.736 0.263
E14.6 With other specified complications
0.000 0.736 0.263
E14.2 Withrenal complications
0.000 0.736 0.263
E14.0 With coma
0.000 0.736 0.263
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.738 0.262
G63 Polyneuropathy in diseases classified elsewhere
0.262 0.738 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.261 0.739 0.000
G02.1 Meningitis in mycoses
0.261 0.739 0.000
G95.1 Vascular myelopathies
0.260 0.740 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.744 0.256
E14.4 With neurological complications
0.000 0.749 0.250
E03.8 Other specified hypothyroidism
0.000 0.751 0.249
G57 Mononeuropathies of lower limb
0.249 0.751 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.247 0.753 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.245 0.755 0.001
G60.8 Other hereditary and idiopathic neuropathies
0.240 0.760 0.000
E03.5 Myxoedema coma
0.000 0.761 0.239
E03.4 Atrophy of thyroid (acquired)
0.000 0.761 0.239
E03.3 Postinfectious hypothyroidism
0.000 0.761 0.239
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.761 0.239
E14.5 With peripheral circulatory complications
0.000 0.761 0.239
G57.8 Other mononeuropathies of lower limb
0.239 0.761 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.238 0.762 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.764 0.236
E00 Congenital iodine-deficiency syndrome
0.000 0.764 0.236
E06 Thyroiditis
0.000 0.764 0.236
E61 Deficiency of other nutrient elements
0.000 0.765 0.235
G60.0 Hereditary motor and sensory neuropathy
0.231 0.769 0.000
L40.0 Psoriasis vulgaris
0.229 0.771 0.000
G44.0 Cluster headache syndrome
0.227 0.772 0.000
G44.8 Other specified headache syndromes
0.225 0.775 0.000
E07.8 Other specified disorders of thyroid
0.000 0.775 0.225
G95.9 Disease of spinal cord, unspecified
0.222 0.778 0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.221 0.779 0.000
G60.3 Idiopathic progressive neuropathy
0.221 0.779 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.221 0.779 0.000
G60.1 Refsum's disease
0.221 0.779 0.000
E53 Deficiency of other B group vitamins
0.000 0.780 0.220
G57.6 Lesion of plantar nerve
0.220 0.780 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.219 0.781 0.000
G83.4 Cauda equina syndrome
0.218 0.782 0.000
G83.2 Monoplegia of upper limb
0.218 0.782 0.000
E55 Vitamin D deficiency
0.000 0.785 0.215
G82.3 Flaccid tetraplegia
0.213 0.787 0.000
G82.0 Flaccid paraplegia
0.213 0.787 0.000
E61.1 Iron deficiency
0.000 0.788 0.212
E16 Other disorders of pancreatic internal secretion
0.000 0.789 0.211
E07.1 Dyshormogenetic goitre
0.000 0.791 0.209
E07.0 Hypersecretion of calcitonin
0.000 0.791 0.209
E58 Dietary calcium deficiency
0.000 0.792 0.208
L40-L45 Papulosquamous disorders
0.207 0.793 0.000
G30.9 Alzheimer's disease, unspecified
0.207 0.793 0.000
G80 Infantile cerebral palsy
0.206 0.794 0.000
G57.1 Meralgia paraesthetica
0.206 0.794 0.000
G83.5 Locked-in syndrome
0.206 0.794 0.000
G83.3 Monoplegia, unspecified
0.206 0.794 0.000
G83.0 Diplegia of upper limbs
0.206 0.794 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.795 0.205
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.796 0.204
E63 Other nutritional deficiencies
0.000 0.796 0.204
E51 Thiamine deficiency
0.000 0.796 0.204
E50 Vitamin A deficiency
0.000 0.796 0.204
E60 Dietary zinc deficiency
0.000 0.796 0.204
E59 Dietary selenium deficiency
0.000 0.796 0.204
E54 Ascorbic acid deficiency
0.000 0.796 0.204
E52 Niacin deficiency [pellagra]
0.000 0.796 0.204
G12.9 Spinal muscular atrophy, unspecified
0.204 0.796 0.001
G12.8 Other spinal muscular atrophies and related syndromes
0.204 0.796 0.001
G12.1 Other inherited spinal muscular atrophy
0.204 0.796 0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.204 0.796 0.001
G83.1 Monoplegia of lower limb
0.203 0.796 0.000
E40-E46 Malnutrition
0.000 0.797 0.203
G82.4 Spastic tetraplegia
0.202 0.798 0.000
G57.5 Tarsal tunnel syndrome
0.200 0.800 0.000
G83.8 Other specified paralytic syndromes
0.199 0.801 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.801 0.199
G00.9 Bacterial meningitis, unspecified
0.197 0.803 0.001
G57.0 Lesion of sciatic nerve
0.197 0.803 0.000
E56 Other vitamin deficiencies
0.000 0.803 0.196
E03.1 Congenital hypothyroidism without goitre
0.000 0.805 0.195
G70 Myasthenia gravis and other myoneural disorders
0.192 0.807 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.192 0.808 0.001
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.190 0.809 0.000
G52 Disorders of other cranial nerves
0.190 0.810 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.812 0.188
G63.8 Polyneuropathy in other diseases classified elsewhere
0.188 0.812 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.188 0.812 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.188 0.812 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.188 0.812 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.188 0.812 0.000
G63.1 Polyneuropathy in neoplastic disease
0.188 0.812 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.188 0.812 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.813 0.187
L42 Pityriasis rosea
0.184 0.816 0.000
E06.3 Autoimmune thyroiditis
0.000 0.817 0.183
G83.9 Paralytic syndrome, unspecified
0.181 0.819 0.000
E24 Cushing's syndrome
0.000 0.820 0.179
G91 Hydrocephalus
0.178 0.821 0.001
G57.4 Lesion of medial popliteal nerve
0.178 0.821 0.000
G57.2 Lesion of femoral nerve
0.178 0.821 0.000
M06 Other rheumatoid arthritis
0.000 0.821 0.178
G57.9 Mononeuropathy of lower limb, unspecified
0.176 0.824 0.000
G71 Primary disorders of muscles
0.175 0.825 0.000
G90 Disorders of autonomic nervous system
0.171 0.827 0.002
G82.5 Tetraplegia, unspecified
0.172 0.827 0.000
E16.1 Other hypoglycaemia
0.000 0.828 0.172
E53.8 Deficiency of other specified B group vitamins
0.000 0.828 0.172
G73.7 Myopathy other diseases classified elsewhere
0.170 0.829 0.000
G73.6 Myopathy in metabolic diseases
0.170 0.829 0.000
G73.5 Myopathy in endocrine diseases
0.170 0.829 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.170 0.829 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.170 0.829 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.170 0.829 0.000
G73.1 Eaton-Lambert syndrome
0.170 0.829 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.170 0.829 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.830 0.170
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.830 0.170
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.830 0.170
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.830 0.170
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.830 0.170
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.830 0.170
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.830 0.170
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.830 0.170
E06.5 Other chronic thyroiditis
0.000 0.831 0.169
E06.4 Drug-induced thyroiditis
0.000 0.831 0.169
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.831 0.169
E06.1 Subacute thyroiditis
0.000 0.831 0.169
E06.0 Acute thyroiditis
0.000 0.831 0.169
E61.9 Deficiency of nutrient element, unspecified
0.000 0.831 0.169
E61.8 Deficiency of other specified nutrient elements
0.000 0.831 0.169
E61.7 Deficiency of multiple nutrient elements
0.000 0.831 0.169
E61.6 Vanadium deficiency
0.000 0.831 0.169
E61.5 Molybdenum deficiency
0.000 0.831 0.169
E61.4 Chromium deficiency
0.000 0.831 0.169
E61.3 Manganese deficiency
0.000 0.831 0.169
E61.0 Copper deficiency
0.000 0.831 0.169
G63.2 Diabetic polyneuropathy
0.169 0.831 0.000
G93.0 Cerebral cysts
0.165 0.833 0.002
G58 Other mononeuropathies
0.166 0.834 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.834 0.166
G57.3 Lesion of lateral popliteal nerve
0.165 0.834 0.000
G81 Hemiplegia
0.163 0.837 0.001
G80.8 Other infantile cerebral palsy
0.162 0.837 0.000
E22 Hyperfunction of pituitary gland
0.000 0.838 0.162
E53.9 Vitamin B deficiency, unspecified
0.000 0.839 0.160
E53.1 Pyridoxine deficiency
0.000 0.842 0.158
E53.0 Riboflavin deficiency
0.000 0.842 0.158
E24.9 Cushing's syndrome, unspecified
0.000 0.843 0.157
G93.9 Disorder of brain, unspecified
0.155 0.844 0.001
E55.0 Rickets, active
0.000 0.845 0.154
G82.2 Paraplegia, unspecified
0.154 0.846 0.000
G72 Other myopathies
0.153 0.846 0.001
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.846 0.154
E28 Ovarian dysfunction
0.000 0.847 0.153
G52.8 Disorders of other specified cranial nerves
0.153 0.847 0.000
E06.9 Thyroiditis, unspecified
0.000 0.849 0.151
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.849 0.151
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.849 0.151
E16.4 Abnormal secretion of gastrin
0.000 0.849 0.151
E16.3 Increased secretion of glucagon
0.000 0.849 0.151
G80.2 Infantile hemiplegia
0.148 0.851 0.000
L44 Other papulosquamous disorders
0.148 0.851 0.000
L41 Parapsoriasis
0.148 0.851 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.148 0.851 0.000
G80.4 Ataxic cerebral palsy
0.148 0.852 0.000
G80.3 Dyskinetic cerebral palsy
0.148 0.852 0.000
I83 Varicose veins of lower extremities
0.148 0.852 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.853 0.146
E50.8 Other manifestations of vitamin A deficiency
0.000 0.853 0.146
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.853 0.146
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.853 0.146
E50.5 Vitamin A deficiency with night blindness
0.000 0.853 0.146
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.853 0.146
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.853 0.146
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.853 0.146
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.853 0.146
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.853 0.146
E51.9 Thiamine deficiency, unspecified
0.000 0.853 0.146
E51.8 Other manifestations of thiamine deficiency
0.000 0.853 0.146
E51.2 Wernicke's encephalopathy
0.000 0.853 0.146
E51.1 Beriberi
0.000 0.853 0.146
E63.9 Nutritional deficiency, unspecified
0.000 0.853 0.146
E63.8 Other specified nutritional deficiencies
0.000 0.853 0.146
E63.1 Imbalance of constituents of food intake
0.000 0.853 0.146
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.853 0.146
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.853 0.146
E64.8 Sequelae of other nutritional deficiencies
0.000 0.853 0.146
E64.3 Sequelae of rickets
0.000 0.853 0.146
E64.2 Sequelae of vitamin C deficiency
0.000 0.853 0.146
E64.1 Sequelae of vitamin A deficiency
0.000 0.853 0.146
E64.0 Sequelae of protein-energy malnutrition
0.000 0.853 0.146
G62 Other polyneuropathies
0.146 0.854 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.854 0.145
E45 Retarded development following protein-energy malnutrition
0.000 0.854 0.145
E43 Unspecified severe protein-energy malnutrition
0.000 0.854 0.145
E42 Marasmic kwashiorkor
0.000 0.854 0.145
E41 Nutritional marasmus
0.000 0.854 0.145
E40 Kwashiorkor
0.000 0.854 0.145
G80.0 Spastic cerebral palsy
0.145 0.855 0.000
G31.8 Other specified degenerative diseases of nervous system
0.142 0.856 0.001
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.857 0.143
E32 Diseases of thymus
0.000 0.857 0.143
E31 Polyglandular dysfunction
0.000 0.857 0.143
E30 Disorders of puberty, not elsewhere classified
0.000 0.857 0.143
G61 Inflammatory polyneuropathy
0.142 0.858 0.001
E56.9 Vitamin deficiency, unspecified
0.000 0.859 0.141
E56.8 Deficiency of other vitamins
0.000 0.859 0.141
E56.0 Deficiency of vitamin E
0.000 0.859 0.141
E23 Hypofunction and other disorders of pituitary gland
0.000 0.859 0.141
E24.0 Pituitary-dependent Cushing's disease
0.000 0.861 0.139
E24.2 Drug-induced Cushing's syndrome
0.000 0.861 0.139
G59 Mononeuropathy in diseases classified elsewhere
0.139 0.861 0.000
G70.9 Myoneural disorder, unspecified
0.138 0.861 0.000
G70.8 Other specified myoneural disorders
0.138 0.862 0.000
G70.2 Congenital and developmental myasthenia
0.138 0.862 0.000
G70.1 Toxic myoneural disorders
0.138 0.862 0.000
E61.2 Magnesium deficiency
0.000 0.863 0.136
G52.7 Disorders of multiple cranial nerves
0.136 0.864 0.000
G52.3 Disorders of hypoglossal nerve
0.136 0.864 0.000
G52.2 Disorders of vagus nerve
0.136 0.864 0.000
G52.1 Disorders of glossopharyngeal nerve
0.136 0.864 0.000
G52.0 Disorders of olfactory nerve
0.136 0.864 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.134 0.865 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.133 0.867 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.867 0.133
E56.1 Deficiency of vitamin K
0.000 0.867 0.133

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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