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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2255221
log Bayes Factor = 14.572
Chromosome 6   position 31,431,691  (GRCh37) Explore rs2255221 on Ensembl!
Variant rs2255221 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.021 0.979
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.048 0.952
M06 Other rheumatoid arthritis
0.000 0.070 0.930
E10.1 With ketoacidosis
0.000 0.083 0.917
E14 Unspecified diabetes mellitus
0.000 0.087 0.913
E20-E35 Disorders of other endocrine glands
0.000 0.099 0.901
E06 Thyroiditis
0.000 0.102 0.898
E27 Other disorders of adrenal gland
0.000 0.103 0.897
M06.0 Seronegative rheumatoid arthritis
0.000 0.120 0.880
L40.0 Psoriasis vulgaris
0.000 0.132 0.868
E27.1 Primary adrenocortical insufficiency
0.000 0.132 0.868
E10.4 With neurological complications
0.000 0.134 0.866
E11 Non-insulin-dependent diabetes mellitus
0.000 0.136 0.864
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.139 0.861
E65-E68 Obesity and other hyperalimentation
0.000 0.141 0.859
E10.2 With renal complications
0.000 0.150 0.850
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.155 0.845
E14.9 Without complications
0.000 0.157 0.843
E11.3 With ophthalmic complications
0.000 0.162 0.838
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.162 0.838
E06.3 Autoimmune thyroiditis
0.000 0.179 0.821
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.180 0.820
E66 Obesity
0.000 0.213 0.786
E50-E64 Other nutritional deficiencies
0.000 0.215 0.785
E10.5 With peripheral circulatory complications
0.000 0.222 0.778
E66.8 Other obesity
0.000 0.227 0.773
E40-E46 Malnutrition
0.000 0.228 0.771
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.232 0.768
E27.8 Other specified disorders of adrenal gland
0.000 0.234 0.766
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.239 0.761
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.253 0.747
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.258 0.742
E03.8 Other specified hypothyroidism
0.000 0.259 0.741
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.270 0.730
L40.8 Other psoriasis
0.000 0.281 0.719
E14.3 With ophthalmic complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.289 0.711
M05-M14 Inflammatory polyarthropathies
0.000 0.293 0.707
E10.8 With unspecified complications
0.000 0.296 0.703
E11.2 With renal complications
0.000 0.301 0.699
M07 Psoriatic and enteropathic arthropathies
0.000 0.307 0.693
E11.1 With ketoacidosis
0.000 0.312 0.688
E11.5 With peripheral circulatory complications
0.000 0.315 0.685
M07.3 Other psoriatic arthropathies
0.000 0.317 0.683
E11.8 With unspecified complications
0.000 0.330 0.670
E53 Deficiency of other B group vitamins
0.000 0.331 0.669
M06.8 Other specified rheumatoid arthritis
0.000 0.333 0.667
M06.2 Rheumatoid bursitis
0.000 0.333 0.667
M06.1 Adult-onset Still's disease
0.000 0.333 0.667
E83.1 Disorders of iron metabolism
0.662 0.337 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.338 0.662
E26 Hyperaldosteronism
0.000 0.340 0.660
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.342 0.658
E06.9 Thyroiditis, unspecified
0.000 0.342 0.657
E14.8 With unspecified complications
0.000 0.345 0.655
E14.7 With multiple complications
0.000 0.345 0.655
E14.6 With other specified complications
0.000 0.345 0.655
E14.5 With peripheral circulatory complications
0.000 0.345 0.655
E14.2 Withrenal complications
0.000 0.345 0.655
E14.1 With ketoacidosis
0.000 0.345 0.655
E14.0 With coma
0.000 0.345 0.655
E20 Hypoparathyroidism
0.000 0.349 0.651
M06.3 Rheumatoid nodule
0.000 0.351 0.649
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.354 0.646
E32 Diseases of thymus
0.000 0.354 0.646
E31 Polyglandular dysfunction
0.000 0.354 0.646
E30 Disorders of puberty, not elsewhere classified
0.000 0.354 0.646
E25 Adrenogenital disorders
0.000 0.354 0.646
M06.4 Inflammatory polyarthropathy
0.000 0.356 0.644
E06.5 Other chronic thyroiditis
0.000 0.356 0.644
E06.4 Drug-induced thyroiditis
0.000 0.356 0.644
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.356 0.644
E06.1 Subacute thyroiditis
0.000 0.356 0.644
E06.0 Acute thyroiditis
0.000 0.356 0.644
E27.5 Adrenomedullary hyperfunction
0.000 0.356 0.643
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.356 0.643
E27.2 Addisonian crisis
0.000 0.356 0.643
E27.0 Other adrenocortical overactivity
0.000 0.356 0.643
E05.9 Thyrotoxicosis, unspecified
0.000 0.362 0.638
E22 Hyperfunction of pituitary gland
0.000 0.368 0.632
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.369 0.631
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.369 0.631
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.369 0.631
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.369 0.631
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.369 0.631
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.369 0.631
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.369 0.631
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.379 0.621
E11.7 With multiple complications
0.000 0.380 0.619
E67 Other hyperalimentation
0.000 0.384 0.616
E68 Sequelae of hyperalimentation
0.000 0.384 0.616
E27.9 Disorder of adrenal gland, unspecified
0.000 0.386 0.614
E14.4 With neurological complications
0.000 0.389 0.611
E46 Unspecified protein-energy malnutrition
0.000 0.392 0.608
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.396 0.604
E05.5 Thyroid crisis or storm
0.000 0.399 0.601
E05.4 Thyrotoxicosis factitia
0.000 0.399 0.601
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.399 0.601
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.399 0.601
E13 Other specified diabetes mellitus
0.000 0.400 0.600
E03.1 Congenital hypothyroidism without goitre
0.000 0.403 0.597
E24 Cushing's syndrome
0.000 0.407 0.593
E53.8 Deficiency of other specified B group vitamins
0.000 0.414 0.586
E11.6 With other specified complications
0.000 0.419 0.581
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.422 0.577
E04 Other non-toxic goitre
0.000 0.426 0.574
E07 Other disorders of thyroid
0.000 0.426 0.574
E55 Vitamin D deficiency
0.000 0.429 0.571
E66.1 Drug-induced obesity
0.000 0.436 0.564
E66.0 Obesity due to excess calories
0.000 0.436 0.564
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.437 0.563
E63 Other nutritional deficiencies
0.000 0.437 0.563
E56 Other vitamin deficiencies
0.000 0.437 0.563
E51 Thiamine deficiency
0.000 0.437 0.563
E50 Vitamin A deficiency
0.000 0.437 0.563
E60 Dietary zinc deficiency
0.000 0.437 0.563
E59 Dietary selenium deficiency
0.000 0.437 0.563
E58 Dietary calcium deficiency
0.000 0.437 0.563
E54 Ascorbic acid deficiency
0.000 0.437 0.563
E52 Niacin deficiency [pellagra]
0.000 0.437 0.563
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.437 0.563
E23 Hypofunction and other disorders of pituitary gland
0.000 0.438 0.562
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.442 0.557
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.447 0.553
E45 Retarded development following protein-energy malnutrition
0.000 0.447 0.553
E43 Unspecified severe protein-energy malnutrition
0.000 0.447 0.553
E42 Marasmic kwashiorkor
0.000 0.447 0.553
E41 Nutritional marasmus
0.000 0.447 0.553
E40 Kwashiorkor
0.000 0.447 0.553
M14 Arthropathies in other diseases classified elsewhere
0.000 0.448 0.552
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.455 0.545
E29 Testicular dysfunction
0.000 0.472 0.528
E28 Ovarian dysfunction
0.000 0.472 0.528
E22.0 Acromegaly and pituitary gigantism
0.000 0.477 0.523
E65 Localised adiposity
0.000 0.478 0.521
E34 Other endocrine disorders
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
L40-L45 Papulosquamous disorders
0.000 0.492 0.508
M12 Other specific arthropathies
0.000 0.493 0.507
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.493 0.507
M08 Juvenile arthritis
0.000 0.493 0.507
M07.6 Other enteropathic arthropathies
0.000 0.503 0.497
M07.5 Arthropathy in ulcerative colitis
0.000 0.503 0.497
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.503 0.497
M07.2 Psoriatic spondylitis
0.000 0.503 0.497
M07.1 Arthritis mutilans
0.000 0.503 0.497
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.503 0.497
M05 Seropositive rheumatoid arthritis
0.000 0.506 0.494
E05.8 Other thyrotoxicosis
0.000 0.509 0.491
M07.38 Other psoriatic arthropathies (Other)
0.000 0.510 0.489
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.510 0.489
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.510 0.489
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.510 0.489
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.510 0.489
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.510 0.489
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.510 0.489
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.510 0.489
E26.0 Primary hyperaldosteronism
0.000 0.513 0.486
E61 Deficiency of other nutrient elements
0.000 0.518 0.482
E53.9 Vitamin B deficiency, unspecified
0.000 0.520 0.480
E53.1 Pyridoxine deficiency
0.000 0.520 0.480
E53.0 Riboflavin deficiency
0.000 0.520 0.480
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.522 0.478
M06.18 Adult-onset Still's disease (Other)
0.000 0.522 0.478
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.522 0.478
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.522 0.478
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.522 0.478
M06.14 Adult-onset Still's disease (Hand)
0.000 0.522 0.478
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.522 0.478
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.522 0.478
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.522 0.478
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.522 0.478
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.522 0.478
M06.28 Rheumatoid bursitis (Other)
0.000 0.522 0.478
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.522 0.478
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.522 0.478
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.522 0.478
M06.24 Rheumatoid bursitis (Hand)
0.000 0.522 0.478
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.522 0.478
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.522 0.478
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.522 0.478
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.522 0.478
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.522 0.478
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.522 0.478
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.522 0.478
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.522 0.478
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.522 0.478
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.522 0.478
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.522 0.478
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.522 0.478
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.522 0.478
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.522 0.478
E26.9 Hyperaldosteronism, unspecified
0.000 0.527 0.473
E26.8 Other hyperaldosteronism
0.000 0.527 0.473
E26.1 Secondary hyperaldosteronism
0.000 0.527 0.473
E20.9 Hypoparathyroidism, unspecified
0.000 0.528 0.471
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.529 0.471
E20.8 Other hypoparathyroidism
0.000 0.533 0.467
E20.1 Pseudohypoparathyroidism
0.000 0.533 0.467
E20.0 Idiopathic hypoparathyroidism
0.000 0.533 0.467
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.534 0.466
M06.38 Rheumatoid nodule (Other)
0.000 0.534 0.466
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.534 0.466
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.534 0.466
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.534 0.466
M06.33 Rheumatoid nodule (Forearm)
0.000 0.534 0.466
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.534 0.466
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.534 0.466
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.534 0.466
E25.9 Adrenogenital disorder, unspecified
0.000 0.536 0.463
E25.8 Other adrenogenital disorders
0.000 0.536 0.463
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.536 0.463
E30.9 Disorder of puberty, unspecified
0.000 0.536 0.463
E30.8 Other disorders of puberty
0.000 0.536 0.463
E30.1 Precocious puberty
0.000 0.536 0.463
E30.0 Delayed puberty
0.000 0.536 0.463
E31.9 Polyglandular dysfunction, unspecified
0.000 0.536 0.463
E31.8 Other polyglandular dysfunction
0.000 0.536 0.463
E31.1 Polyglandular hyperfunction
0.000 0.536 0.463
E31.0 Autoimmune polyglandular failure
0.000 0.536 0.463
E32.9 Disease of thymus, unspecified
0.000 0.536 0.463
E32.8 Other diseases of thymus
0.000 0.536 0.463
E32.1 Abscess of thymus
0.000 0.536 0.463
E32.0 Persistent hyperplasia of thymus
0.000 0.536 0.463
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.536 0.463
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.536 0.463
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.536 0.463
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.538 0.462
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.538 0.462
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.538 0.462
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.538 0.462
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.538 0.462
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.538 0.462
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.538 0.462
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.538 0.462
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.547 0.453
E22.8 Other hyperfunction of pituitary gland
0.000 0.547 0.453
E04.0 Non-toxic diffuse goitre
0.000 0.548 0.452
E11.0 With coma
0.000 0.548 0.451
M06.34 Rheumatoid nodule (Hand)
0.000 0.552 0.448
E67.8 Other specified hyperalimentation
0.000 0.558 0.441
E67.3 Hypervitaminosis D
0.000 0.558 0.441
E67.2 Megavitamin-B6 syndrome
0.000 0.558 0.441
E67.1 Hypercarotenaemia
0.000 0.558 0.441
E67.0 Hypervitaminosis A
0.000 0.558 0.441
M14.6 Neuropathic arthropathy
0.000 0.559 0.441
E22.1 Hyperprolactinaemia
0.000 0.560 0.440
E13.8 With unspecified complications
0.000 0.570 0.430
E13.7 With multiple complications
0.000 0.570 0.430
E13.6 With other specified complications
0.000 0.570 0.430
E13.5 With peripheral circulatory complications
0.000 0.570 0.430
E13.4 With neurological complications
0.000 0.570 0.430
E13.3 With ophthalmic complications
0.000 0.570 0.430
E13.2 With renal complications
0.000 0.570 0.430
E13.1 With ketoacidosis
0.000 0.570 0.430
E13.0 With coma
0.000 0.570 0.430
M11 Other crystal arthropathies
0.000 0.570 0.430
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.572 0.428
E23.2 Diabetes insipidus
0.000 0.573 0.427
E24.8 Other Cushing's syndrome
0.000 0.575 0.425
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.575 0.425
E24.3 Ectopic ACTH syndrome
0.000 0.575 0.425
E24.2 Drug-induced Cushing's syndrome
0.000 0.575 0.425
E24.1 Nelson's syndrome
0.000 0.575 0.425
E24.0 Pituitary-dependent Cushing's disease
0.000 0.575 0.425
E55.9 Vitamin D deficiency, unspecified
0.000 0.582 0.418
M10 Gout
0.000 0.588 0.412
E04.8 Other specified non-toxic goitre
0.000 0.588 0.412
E07.8 Other specified disorders of thyroid
0.000 0.588 0.412
E07.1 Dyshormogenetic goitre
0.000 0.588 0.412
E07.0 Hypersecretion of calcitonin
0.000 0.588 0.412
S61.0 Open wound of finger(s) without damage to nail
0.410 0.590 0.000
E55.0 Rickets, active
0.000 0.590 0.410
E50.9 Vitamin A deficiency, unspecified
0.000 0.596 0.404
E50.8 Other manifestations of vitamin A deficiency
0.000 0.596 0.404
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.596 0.404
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.596 0.404
E50.5 Vitamin A deficiency with night blindness
0.000 0.596 0.404
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.596 0.404
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.596 0.404
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.596 0.404
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.596 0.404
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.596 0.404
E51.9 Thiamine deficiency, unspecified
0.000 0.596 0.404
E51.8 Other manifestations of thiamine deficiency
0.000 0.596 0.404
E51.2 Wernicke's encephalopathy
0.000 0.596 0.404
E51.1 Beriberi
0.000 0.596 0.404
E56.9 Vitamin deficiency, unspecified
0.000 0.596 0.404
E56.8 Deficiency of other vitamins
0.000 0.596 0.404
E56.1 Deficiency of vitamin K
0.000 0.596 0.404
E56.0 Deficiency of vitamin E
0.000 0.596 0.404
E63.9 Nutritional deficiency, unspecified
0.000 0.596 0.404
E63.8 Other specified nutritional deficiencies
0.000 0.596 0.404
E63.1 Imbalance of constituents of food intake
0.000 0.596 0.404
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.596 0.404
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.596 0.404
E64.8 Sequelae of other nutritional deficiencies
0.000 0.596 0.404
E64.3 Sequelae of rickets
0.000 0.596 0.404
E64.2 Sequelae of vitamin C deficiency
0.000 0.596 0.404
E64.1 Sequelae of vitamin A deficiency
0.000 0.596 0.404
E64.0 Sequelae of protein-energy malnutrition
0.000 0.596 0.404
E23.7 Disorder of pituitary gland, unspecified
0.000 0.597 0.403
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.597 0.403
E23.1 Drug-induced hypopituitarism
0.000 0.597 0.403
E15 Nondiabetic hypoglycaemic coma
0.000 0.600 0.400
S06 Intracranial injury
0.398 0.602 0.000
S61 Open wound of wrist and hand
0.398 0.602 0.000
S00-S09 Injuries to the head
0.397 0.603 0.000
S02 Fracture of skull and facial bones
0.397 0.603 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.603 0.397
E44.0 Moderate protein-energy malnutrition
0.000 0.603 0.397
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.604 0.396
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.604 0.396
M14.4 Arthropathy in amyloidosis
0.000 0.604 0.396
M14.3 Lipoid dermatoarthritis
0.000 0.604 0.396
M14.2 Diabetic arthropathy
0.000 0.604 0.396
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.604 0.396
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.604 0.396
E04.1 Non-toxic single thyroid nodule
0.000 0.616 0.384
S60-S69 Injuries to the wrist and hand
0.384 0.616 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.383 0.617 0.000
E23.6 Other disorders of pituitary gland
0.000 0.621 0.379
E29.9 Testicular dysfunction, unspecified
0.000 0.621 0.379
E29.8 Other testicular dysfunction
0.000 0.621 0.379
E29.0 Testicular hyperfunction
0.000 0.621 0.379
E28.9 Ovarian dysfunction, unspecified
0.000 0.621 0.379
E28.8 Other ovarian dysfunction
0.000 0.621 0.379
E28.3 Primary ovarian failure
0.000 0.621 0.379
E28.1 Androgen excess
0.000 0.621 0.379
E28.0 Oestrogen excess
0.000 0.621 0.379
S61.8 Open wound of other parts of wrist and hand
0.373 0.627 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.628 0.372
E34.8 Other specified endocrine disorders
0.000 0.630 0.370
E34.5 Androgen resistance syndrome
0.000 0.630 0.370
E34.4 Constitutional tall stature
0.000 0.630 0.370
E34.3 Short stature, not elsewhere classified
0.000 0.630 0.370
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.630 0.370
E34.1 Other hypersecretion of intestinal hormones
0.000 0.630 0.370
L44 Other papulosquamous disorders
0.000 0.636 0.364
L41 Parapsoriasis
0.000 0.636 0.364
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.636 0.364
M08.9 Juvenile arthritis, unspecified
0.000 0.636 0.364
M08.8 Other juvenile arthritis
0.000 0.636 0.364
M08.4 Pauciarticular juvenile arthritis
0.000 0.636 0.364
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.636 0.364
M08.2 Juvenile arthritis with systemic onset
0.000 0.636 0.364
M08.1 Juvenile ankylosing spondylitis
0.000 0.636 0.364
M08.0 Juvenile rheumatoid arthritis
0.000 0.636 0.364
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.636 0.364
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.636 0.364
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.636 0.364
M09.0 Juvenile arthritis in psoriasis
0.000 0.636 0.364
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.636 0.364
M12.5 Traumatic arthropathy
0.000 0.636 0.364
M12.4 Intermittent hydrarthrosis
0.000 0.636 0.364
M12.3 Palindromic rheumatism
0.000 0.636 0.364
M12.2 Villonodular synovitis (pigmented)
0.000 0.636 0.364
M12.1 Kaschin-Beck disease
0.000 0.636 0.364
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.636 0.364
E04.9 Non-toxic goitre, unspecified
0.000 0.643 0.357
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.644 0.356
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.644 0.356
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.644 0.356
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.644 0.356
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.644 0.356
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.644 0.356
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.644 0.356
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.644 0.356
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.644 0.356
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.644 0.356
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.644 0.356
M07.18 Arthritis mutilans (Other)
0.000 0.644 0.356
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.644 0.356
M07.16 Arthritis mutilans (Lower leg)
0.000 0.644 0.356
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.644 0.356
M07.14 Arthritis mutilans (Hand)
0.000 0.644 0.356
M07.13 Arthritis mutilans (Forearm)
0.000 0.644 0.356
M07.12 Arthritis mutilans (Upper arm)
0.000 0.644 0.356
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.644 0.356
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.644 0.356
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.644 0.356
M07.28 Psoriatic spondylitis (Other)
0.000 0.644 0.356
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.644 0.356
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.644 0.356
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.644 0.356
M07.24 Psoriatic spondylitis (Hand)
0.000 0.644 0.356
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.644 0.356
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.644 0.356
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.644 0.356
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.644 0.356
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.644 0.356
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.644 0.356
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.644 0.356
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.644 0.356
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.644 0.356
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.644 0.356
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.644 0.356
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.644 0.356
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.644 0.356
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.644 0.356
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.644 0.356
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.644 0.356
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.644 0.356
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.644 0.356
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.000 0.644 0.356
M07.54 Arthropathy in ulcerative colitis (Hand)
0.000 0.644 0.356
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.000 0.644 0.356
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.000 0.644 0.356
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.000 0.644 0.356
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.000 0.644 0.356
M07.69 Other enteropathic arthropathies (Site unspecified)
0.000 0.644 0.356
M07.68 Other enteropathic arthropathies (Other)
0.000 0.644 0.356
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.000 0.644 0.356
M07.66 Other enteropathic arthropathies (Lower leg)
0.000 0.644 0.356
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.000 0.644 0.356
M07.64 Other enteropathic arthropathies (Hand)
0.000 0.644 0.356
M07.63 Other enteropathic arthropathies (Forearm)
0.000 0.644 0.356
M07.62 Other enteropathic arthropathies (Upper arm)
0.000 0.644 0.356
M07.61 Other enteropathic arthropathies (Shoulder region)
0.000 0.644 0.356
M07.60 Other enteropathic arthropathies (Multiple sites)
0.000 0.644 0.356
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.644 0.356
E11.4 With neurological complications
0.000 0.645 0.355
M05.8 Other seropositive rheumatoid arthritis
0.000 0.646 0.354
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.646 0.354
M05.2 Rheumatoid vasculitis
0.000 0.646 0.354
M05.1 Rheumatoid lung disease
0.000 0.646 0.354
M05.0 Felty's syndrome
0.000 0.646 0.354
S90-S99 Injuries to the ankle and foot
0.354 0.646 0.000
S06.5 Traumatic subdural haemorrhage
0.350 0.650 0.000
M13 Other arthritis
0.001 0.651 0.349
S02.1 Fracture of base of skull
0.348 0.652 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.347 0.653 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.654 0.345
E61.8 Deficiency of other specified nutrient elements
0.000 0.654 0.345
E61.7 Deficiency of multiple nutrient elements
0.000 0.654 0.345
E61.6 Vanadium deficiency
0.000 0.654 0.345
E61.5 Molybdenum deficiency
0.000 0.654 0.345
E61.4 Chromium deficiency
0.000 0.654 0.345
E61.3 Manganese deficiency
0.000 0.654 0.345
E61.2 Magnesium deficiency
0.000 0.654 0.345
E61.0 Copper deficiency
0.000 0.654 0.345
L20-L30 Dermatitis and eczema
0.000 0.656 0.344
S06.2 Diffuse brain injury
0.343 0.657 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.659 0.341
S66 Injury of muscle and tendon at wrist and hand level
0.341 0.659 0.000
S06.3 Focal brain injury
0.340 0.660 0.000
S70-S79 Injuries to the hip and thigh
0.340 0.660 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.661 0.338
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.664 0.336
S02.4 Fracture of malar and maxillary bones
0.335 0.665 0.000
S02.8 Fractures of other skull and facial bones
0.335 0.665 0.000
S80-S89 Injuries to the knee and lower leg
0.334 0.666 0.000
S02.5 Fracture of tooth
0.331 0.669 0.000
L29 Pruritus
0.000 0.669 0.331

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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