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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2264750
log Bayes Factor = 9.22565
Chromosome 12   position 121,450,165  (GRCh37) Explore rs2264750 on Ensembl!
Variant rs2264750 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.000 1.000
K80 Cholelithiasis
0.000 0.000 1.000
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.998 0.002 0.000
I25.1 Atherosclerotic heart disease
0.993 0.007 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.978 0.022 0.000
I25 Chronic ischaemic heart disease
0.967 0.033 0.000
I20-I25 Ischaemic heart diseases
0.964 0.036 0.000
I20.0 Unstable angina
0.958 0.042 0.000
I20 Angina pectoris
0.958 0.042 0.000
E70-E90 Metabolic disorders
0.939 0.061 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.939 0.061 0.000
E87.6 Hypokalaemia
0.926 0.074 0.000
I50 Heart failure
0.921 0.079 0.000
I50.1 Left ventricular failure
0.921 0.079 0.000
Chapter IX Diseases of the circulatory system
0.918 0.082 0.000
I30-I52 Other forms of heart disease
0.917 0.083 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.083 0.917
I34 Nonrheumatic mitral valve disorders
0.912 0.088 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.912 0.088 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.909 0.091 0.000
E88 Other metabolic disorders
0.907 0.093 0.000
K81 Cholecystitis
0.000 0.095 0.905
I95.1 Orthostatic hypotension
0.905 0.095 0.000
I95 Hypotension
0.904 0.096 0.000
I34.1 Mitral (valve) prolapse
0.903 0.097 0.000
E87.5 Hyperkalaemia
0.899 0.101 0.000
E87.2 Acidosis
0.898 0.102 0.000
K81.1 Chronic cholecystitis
0.000 0.110 0.890
I25.0 Atherosclerotic cardiovascular disease, so described
0.882 0.117 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.881 0.119 0.000
K80.8 Other cholelithiasis
0.000 0.134 0.866
I34.0 Mitral (valve) insufficiency
0.849 0.151 0.000
E78.4 Other hyperlipidaemia
0.846 0.154 0.000
I22 Subsequent myocardial infarction
0.843 0.157 0.000
I50.0 Congestive heart failure
0.843 0.157 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.816 0.184 0.000
K80.4 Calculus of bile duct with cholecystitis
0.000 0.191 0.809
I05-I09 Chronic rheumatic heart diseases
0.801 0.199 0.000
I20.8 Other forms of angina pectoris
0.789 0.211 0.000
I95.2 Hypotension due to drugs
0.785 0.214 0.000
K81.0 Acute cholecystitis
0.000 0.226 0.774
K82 Other diseases of gallbladder
0.000 0.235 0.765
I97.1 Other functional disturbances following cardiac surgery
0.760 0.240 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.757 0.243 0.000
I22.8 Subsequent myocardial infarction of other sites
0.747 0.253 0.000
E78.1 Pure hyperglyceridaemia
0.743 0.257 0.000
K85 Acute pancreatitis
0.000 0.257 0.743
K82.4 Cholesterolosis of gallbladder
0.000 0.262 0.738
I30 Acute pericarditis
0.737 0.262 0.000
I25.4 Coronary artery aneurysm
0.731 0.269 0.000
I45 Other conduction disorders
0.728 0.272 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.725 0.275 0.000
E88.3 Tumour lysis syndrome
0.724 0.276 0.000
E87.3 Alkalosis
0.723 0.277 0.000
K80.3 Calculus of bile duct with cholangitis
0.000 0.283 0.717
I45.1 Other and unspecified right bundle-branch block
0.708 0.292 0.000
E72 Other disorders of amino-acid metabolism
0.706 0.294 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.706 0.294 0.000
E78.3 Hyperchylomicronaemia
0.701 0.299 0.000
I37 Pulmonary valve disorders
0.700 0.300 0.000
E70 Disorders of aromatic amino-acid metabolism
0.695 0.305 0.000
I25.6 Silent myocardial ischaemia
0.694 0.306 0.000
E84 Cystic fibrosis
0.693 0.307 0.000
E78.6 Lipoprotein deficiency
0.692 0.308 0.000
I50.9 Heart failure, unspecified
0.684 0.316 0.000
I33 Acute and subacute endocarditis
0.682 0.318 0.000
E88.8 Other specified metabolic disorders
0.679 0.321 0.000
E79 Disorders of purine and pyrimidine metabolism
0.677 0.323 0.000
K81.9 Cholecystitis, unspecified
0.000 0.324 0.676
I34.2 Nonrheumatic mitral (valve) stenosis
0.673 0.327 0.000
E77 Disorders of glycoprotein metabolism
0.673 0.327 0.000
E76 Disorders of glycosaminoglycan metabolism
0.673 0.327 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.673 0.327 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.673 0.327 0.000
E87.4 Mixed disorder of acid-base balance
0.673 0.327 0.000
I06 Rheumatic aortic valve diseases
0.669 0.331 0.000
K85.1 Biliary acute pancreatitis
0.000 0.332 0.668
I43 Cardiomyopathy in diseases classified elsewhere
0.667 0.333 0.000
E88.9 Metabolic disorder, unspecified
0.659 0.341 0.000
I52 Other heart disorders in diseases classified elsewhere
0.657 0.342 0.000
I48 Atrial fibrillation and flutter
0.657 0.342 0.000
I41 Myocarditis in diseases classified elsewhere
0.657 0.342 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.657 0.342 0.000
I32 Pericarditis in diseases classified elsewhere
0.657 0.342 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.343 0.657
I23 Certain current complications following acute myocardial infarction
0.654 0.346 0.000
E78.2 Mixed hyperlipidaemia
0.654 0.346 0.000
I49 Other cardiac arrhythmias
0.652 0.348 0.000
E87.0 Hyperosmolality and hypernatraemia
0.650 0.350 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.650 0.350 0.000
I42 Cardiomyopathy
0.646 0.354 0.000
I00-I02 Acute rheumatic fever
0.641 0.359 0.000
I45.3 Trifascicular block
0.626 0.374 0.000
E78.8 Other disorders of lipoprotein metabolism
0.625 0.375 0.000
K86 Other diseases of pancreas
0.000 0.375 0.625
E88.2 Lipomatosis, not elsewhere classified
0.625 0.375 0.000
E85 Amyloidosis
0.622 0.378 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.621 0.379 0.000
I07 Rheumatic tricuspid valve diseases
0.621 0.379 0.000
I05 Rheumatic mitral valve diseases
0.618 0.382 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.613 0.387 0.000
K81.8 Other cholecystitis
0.000 0.401 0.599
I30.9 Acute pericarditis, unspecified
0.599 0.401 0.000
I51 Complications and ill-defined descriptions of heart disease
0.597 0.403 0.000
E74 Other disorders of carbohydrate metabolism
0.596 0.404 0.000
K86.1 Other chronic pancreatitis
0.000 0.405 0.595
I42.8 Other cardiomyopathies
0.594 0.406 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.594 0.406 0.000
K85.2 Alcohol-induced acute pancreatitis
0.000 0.410 0.590
K82.3 Fistula of gallbladder
0.000 0.412 0.588
I97.9 Postprocedural disorder of circulatory system, unspecified
0.585 0.415 0.000
I97.0 Postcardiotomy syndrome
0.585 0.415 0.000
I37.0 Pulmonary valve stenosis
0.584 0.416 0.000
K82.0 Obstruction of gallbladder
0.000 0.416 0.584
E73 Lactose intolerance
0.577 0.422 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.576 0.424 0.000
I08 Multiple valve diseases
0.576 0.424 0.000
E87.7 Fluid overload
0.575 0.425 0.000
I09 Other rheumatic heart diseases
0.573 0.427 0.000
E75.5 Other lipid storage disorders
0.572 0.428 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.570 0.430 0.000
I25.3 Aneurysm of heart
0.568 0.431 0.000
I36 Nonrheumatic tricuspid valve disorders
0.563 0.436 0.000
I30.8 Other forms of acute pericarditis
0.563 0.437 0.000
I25.5 Ischaemic cardiomyopathy
0.560 0.440 0.000
I40 Acute myocarditis
0.557 0.443 0.000
I31 Other diseases of pericardium
0.555 0.445 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.553 0.447 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.539 0.461 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.538 0.462 0.000
I45.4 Nonspecific intraventricular block
0.535 0.465 0.000
K85.3 Drug-induced acute pancreatitis
0.000 0.467 0.533
I30.0 Acute nonspecific idiopathic pericarditis
0.529 0.471 0.000
I06.1 Rheumatic aortic insufficiency
0.526 0.474 0.000
I45.0 Right fascicular block
0.522 0.478 0.000
I95.8 Other hypotension
0.521 0.478 0.000
E70.3 Albinism
0.521 0.479 0.000
I49.5 Sick sinus syndrome
0.521 0.479 0.000
E75.6 Lipid storage disorder, unspecified
0.520 0.480 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.520 0.480 0.000
E75.3 Sphingolipidosis, unspecified
0.520 0.480 0.000
E75.2 Other sphingolipidosis
0.520 0.480 0.000
E75.1 Other gangliosidosis
0.520 0.480 0.000
E75.0 GM2 gangliosidosis
0.520 0.480 0.000
I51.9 Heart disease, unspecified
0.520 0.480 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.519 0.481 0.000
E84.9 Cystic fibrosis, unspecified
0.517 0.483 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.515 0.484 0.000
I49.4 Other and unspecified premature depolarisation
0.515 0.485 0.000
K82.8 Other specified diseases of gallbladder
0.000 0.485 0.515
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.486 0.514
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.513 0.487 0.000
K86.2 Cyst of pancreas
0.000 0.488 0.512
K82.1 Hydrops of gallbladder
0.000 0.488 0.512
I05.1 Rheumatic mitral insufficiency
0.506 0.493 0.000
I49.3 Ventricular premature depolarisation
0.507 0.493 0.000
I33.0 Acute and subacute infective endocarditis
0.506 0.494 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.506 0.494 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.506 0.494 0.000
E72.5 Disorders of glycine metabolism
0.506 0.494 0.000
E72.4 Disorders of ornithine metabolism
0.506 0.494 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.506 0.494 0.000
E72.2 Disorders of urea cycle metabolism
0.506 0.494 0.000
E72.0 Disorders of amino-acid transport
0.506 0.494 0.000
I30.1 Infective pericarditis
0.505 0.495 0.000
K85.0 Idiopathic acute pancreatitis
0.000 0.495 0.505
I37.9 Pulmonary valve disorder, unspecified
0.502 0.498 0.000
I37.8 Other pulmonary valve disorders
0.502 0.498 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.502 0.498 0.000
I95.0 Idiopathic hypotension
0.499 0.501 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.499 0.501 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.499 0.501 0.000
E70.2 Disorders of tyrosine metabolism
0.499 0.501 0.000
E70.1 Other hyperphenylalaninaemias
0.499 0.501 0.000
E70.0 Classical phenylketonuria
0.499 0.501 0.000
I42.6 Alcoholic cardiomyopathy
0.497 0.503 0.000
E84.8 Cystic fibrosis with other manifestations
0.497 0.503 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.497 0.503 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.497 0.503 0.000
I33.9 Acute endocarditis, unspecified
0.497 0.503 0.000
K85.9 Acute pancreatitis, unspecified
0.000 0.507 0.493
I07.1 Tricuspid insufficiency
0.492 0.508 0.000
E85.9 Amyloidosis, unspecified
0.491 0.509 0.000
I06.0 Rheumatic aortic stenosis
0.490 0.510 0.000
I49.1 Atrial premature depolarisation
0.489 0.511 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.488 0.511 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.485 0.515 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.485 0.515 0.000
E79.1 Lesch-Nyhan syndrome
0.485 0.515 0.000
E71.3 Disorders of fatty-acid metabolism
0.483 0.517 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.483 0.517 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.483 0.517 0.000
E71.0 Maple-syrup-urine disease
0.483 0.517 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.483 0.517 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.483 0.517 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.483 0.517 0.000
E76.2 Other mucopolysaccharidoses
0.483 0.517 0.000
E76.1 Mucopolysaccharidosis, type II
0.483 0.517 0.000
E76.0 Mucopolysaccharidosis, type I
0.483 0.517 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.483 0.517 0.000
E77.8 Other disorders of glycoprotein metabolism
0.483 0.517 0.000
E77.1 Defects in glycoprotein degradation
0.483 0.517 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.483 0.517 0.000
I38 Endocarditis, valve unspecified
0.482 0.518 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.480 0.520 0.000
I06.8 Other rheumatic aortic valve diseases
0.480 0.520 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.478 0.521 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.478 0.521 0.000
I42.9 Cardiomyopathy, unspecified
0.478 0.522 0.000
I51.0 Cardiac septal defect, acquired
0.476 0.524 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.476 0.524 0.000
I49.8 Other specified cardiac arrhythmias
0.474 0.526 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.471 0.528 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.471 0.528 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.471 0.528 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.471 0.528 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.471 0.528 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.471 0.528 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.471 0.528 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.471 0.528 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.471 0.528 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.471 0.528 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.471 0.528 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.471 0.528 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.471 0.528 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.471 0.528 0.000
I48.4 Atypical atrial flutter
0.471 0.528 0.000
I48.3 Typical atrial flutter
0.471 0.528 0.000
I48.2 Chronic atrial fibrillation
0.471 0.528 0.000
I48.1 Persistent atrial fibrillation
0.471 0.528 0.000
I48.0 Paroxysmal atrial fibrillation
0.471 0.528 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.471 0.528 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.471 0.528 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.471 0.528 0.000
K87.1 Disorders of pancreas in diseases classified elsewhere
0.000 0.529 0.471
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.000 0.529 0.471
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.470 0.530 0.000
I45.6 Preexcitation syndrome
0.470 0.530 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.469 0.531 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.469 0.531 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.469 0.531 0.000
I49.2 Junctional premature depolarisation
0.468 0.532 0.000
I42.5 Other restrictive cardiomyopathy
0.463 0.537 0.000
I42.4 Endocardial fibroelastosis
0.463 0.537 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.463 0.537 0.000
I02 Rheumatic chorea
0.460 0.540 0.000
I01 Rheumatic fever with heart involvement
0.460 0.540 0.000
I05.9 Mitral valve disease, unspecified
0.457 0.543 0.000
I31.1 Chronic constrictive pericarditis
0.455 0.544 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.455 0.545 0.000
I51.6 Cardiovascular disease, unspecified
0.453 0.547 0.000
E85.8 Other amyloidosis
0.446 0.554 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.446 0.554 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.446 0.554 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.446 0.554 0.000
I07.9 Tricuspid valve disease, unspecified
0.445 0.555 0.000
I07.8 Other tricuspid valve diseases
0.445 0.555 0.000
I07.2 Tricuspid stenosis with insufficiency
0.445 0.555 0.000
I07.0 Tricuspid stenosis
0.445 0.555 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.444 0.555 0.000
I31.9 Disease of pericardium, unspecified
0.444 0.556 0.000
I00 Rheumatic fever without mention of heart involvement
0.443 0.557 0.000
I05.8 Other mitral valve diseases
0.443 0.557 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.441 0.559 0.000
I45.8 Other specified conduction disorders
0.441 0.559 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.439 0.560 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.439 0.560 0.000
I98.0 Cardiovascular syphilis
0.439 0.560 0.000
I05.0 Mitral stenosis
0.436 0.563 0.000
I37.1 Pulmonary valve insufficiency
0.436 0.563 0.000
I23.8 Other current complications following acute myocardial infarction
0.431 0.568 0.000
I08.9 Multiple valve disease, unspecified
0.431 0.569 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.428 0.572 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.427 0.572 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.427 0.573 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.427 0.573 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.427 0.573 0.000
E74.2 Disorders of galactose metabolism
0.427 0.573 0.000
E74.1 Disorders of fructose metabolism
0.427 0.573 0.000
E74.0 Glycogen storage disease
0.427 0.573 0.000
I42.2 Other hypertrophic cardiomyopathy
0.423 0.577 0.000
E85.3 Secondary systemic amyloidosis
0.422 0.577 0.000
E73.8 Other lactose intolerance
0.414 0.586 0.000
E73.1 Secondary lactase deficiency
0.414 0.586 0.000
E73.0 Congenital lactase deficiency
0.414 0.586 0.000
I51.4 Myocarditis, unspecified
0.413 0.587 0.000
I51.5 Myocardial degeneration
0.413 0.587 0.000
I09.8 Other specified rheumatic heart diseases
0.411 0.589 0.000
I09.2 Chronic rheumatic pericarditis
0.411 0.589 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.411 0.589 0.000
I09.0 Rheumatic myocarditis
0.411 0.589 0.000
I47 Paroxysmal tachycardia
0.411 0.589 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.410 0.590 0.000
I09.9 Rheumatic heart disease, unspecified
0.410 0.590 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.406 0.594 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.404 0.596 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.404 0.596 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.404 0.596 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.404 0.596 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.401 0.599 0.000
I05.2 Mitral stenosis with insufficiency
0.401 0.599 0.000
I40.8 Other acute myocarditis
0.399 0.600 0.000
I40.1 Isolated myocarditis
0.399 0.600 0.000
I20.1 Angina pectoris with documented spasm
0.400 0.600 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.398 0.602 0.000
I31.8 Other specified diseases of pericardium
0.398 0.602 0.000
I31.2 Haemopericardium, not elsewhere classified
0.398 0.602 0.000
I40.9 Acute myocarditis, unspecified
0.392 0.608 0.000
I24 Other acute ischaemic heart diseases
0.388 0.612 0.000
I46 Cardiac arrest
0.387 0.613 0.000
K85.8 Other acute pancreatitis
0.000 0.613 0.386
I28 Other diseases of pulmonary vessels
0.380 0.620 0.000
E89.1 Postprocedural hypoinsulinaemia
0.365 0.635 0.000
E89.4 Postprocedural ovarian failure
0.364 0.636 0.000
I49.9 Cardiac arrhythmia, unspecified
0.360 0.640 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.642 0.358
I08.8 Other multiple valve diseases
0.354 0.645 0.000
E85.4 Organ-limited amyloidosis
0.354 0.646 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.350 0.650 0.000
E89.3 Postprocedural hypopituitarism
0.347 0.653 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.656 0.344
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.341 0.659 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.341 0.659 0.000
E89.5 Postprocedural testicular hypofunction
0.341 0.659 0.000
I31.0 Chronic adhesive pericarditis
0.341 0.659 0.000
K82.2 Perforation of gallbladder
0.001 0.662 0.337
K86.3 Pseudocyst of pancreas
0.000 0.665 0.334
I45.2 Bifascicular block
0.331 0.669 0.000
I95.9 Hypotension, unspecified
0.331 0.669 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.330 0.670 0.000
I01.8 Other acute rheumatic heart disease
0.330 0.670 0.000
I01.2 Acute rheumatic myocarditis
0.330 0.670 0.000
I01.1 Acute rheumatic endocarditis
0.330 0.670 0.000
I01.0 Acute rheumatic pericarditis
0.330 0.670 0.000
I02.9 Rheumatic chorea without heart involvement
0.330 0.670 0.000
I02.0 Rheumatic chorea with heart involvement
0.330 0.670 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.323 0.677 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.321 0.679 0.000
I47.0 Reentry ventricular arrhythmia
0.320 0.679 0.000
I45.9 Conduction disorder, unspecified
0.319 0.681 0.000
E73.9 Lactose intolerance, unspecified
0.318 0.682 0.000
I49.0 Ventricular fibrillation and flutter
0.316 0.684 0.000
I28.8 Other specified diseases of pulmonary vessels
0.316 0.684 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.315 0.684 0.000
I24.1 Dressler's syndrome
0.314 0.686 0.000
E78.5 Hyperlipidaemia, unspecified
0.313 0.687 0.000
I40.0 Infective myocarditis
0.311 0.689 0.001
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.310 0.690 0.000
K86.8 Other specified diseases of pancreas
0.000 0.691 0.309
I25.2 Old myocardial infarction
0.306 0.694 0.000
I45.5 Other specified heart block
0.303 0.696 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.299 0.701 0.000
E83 Disorders of mineral metabolism
0.296 0.704 0.000
E80.6 Other disorders of bilirubin metabolism
0.294 0.706 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.291 0.709 0.000
E80.5 Crigler-Najjar syndrome
0.291 0.709 0.000
E80.3 Defects of catalase and peroxydase
0.291 0.709 0.000
E80.0 Hereditary erythropoietic porphyria
0.291 0.709 0.000
I21 Acute myocardial infarction
0.289 0.711 0.000
I51.8 Other ill-defined heart diseases
0.288 0.712 0.000
K82.9 Disease of gallbladder, unspecified
0.001 0.715 0.285
E89.0 Postprocedural hypothyroidism
0.283 0.717 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.719 0.281
I46.1 Sudden cardiac death, so described
0.278 0.722 0.000
E80.2 Other porphyria
0.277 0.723 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.272 0.727 0.000
I28.1 Aneurysm of pulmonary artery
0.272 0.727 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.272 0.727 0.000
I99 Other and unspecified disorders of circulatory system
0.269 0.730 0.001
E83.4 Disorders of magnesium metabolism
0.269 0.731 0.000
I46.9 Cardiac arrest, unspecified
0.261 0.739 0.000
E80.1 Porphyria cutanea tarda
0.258 0.742 0.000
I27 Other pulmonary heart diseases
0.250 0.750 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.235 0.765 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.234 0.766 0.000
I47.2 Ventricular tachycardia
0.233 0.767 0.000
I27.2 Other secondary pulmonary hypertension
0.223 0.777 0.000
K86.9 Disease of pancreas, unspecified
0.000 0.778 0.222
I21.0 Acute transmural myocardial infarction of anterior wall
0.219 0.781 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.214 0.786 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.212 0.788 0.000
E83.8 Other disorders of mineral metabolism
0.212 0.788 0.000
E83.2 Disorders of zinc metabolism
0.212 0.788 0.000
E83.0 Disorders of copper metabolism
0.212 0.788 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.207 0.793 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.191 0.809 0.000
I08.0 Disorders of both mitral and aortic valves
0.191 0.809 0.000
I26 Pulmonary embolism
0.181 0.816 0.002
I27.8 Other specified pulmonary heart diseases
0.180 0.820 0.000
I21.9 Acute myocardial infarction, unspecified
0.180 0.820 0.000
I27.1 Kyphoscoliotic heart disease
0.179 0.820 0.000
E89.2 Postprocedural hypoparathyroidism
0.179 0.821 0.001
I21.2 Acute transmural myocardial infarction of other sites
0.174 0.826 0.000
I21.4 Acute subendocardial myocardial infarction
0.147 0.853 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.143 0.857 0.000
E80.4 Gilbert's syndrome
0.135 0.864 0.000
I31.3 Pericardial effusion (noninflammatory)
0.135 0.865 0.000
I51.7 Cardiomegaly
0.129 0.871 0.000
E83.3 Disorders of phosphorus metabolism
0.125 0.874 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.123 0.876 0.002
I70-I79 Diseases of arteries, arterioles and capillaries
0.115 0.885 0.000
I10-I15 Hypertensive diseases
0.109 0.891 0.000
I72 Other aneurysm
0.094 0.906 0.000
I47.1 Supraventricular tachycardia
0.092 0.908 0.000
I20.9 Angina pectoris, unspecified
0.092 0.908 0.000
I35 Nonrheumatic aortic valve disorders
0.090 0.910 0.000
I78 Diseases of capillaries
0.090 0.910 0.000
I27.9 Pulmonary heart disease, unspecified
0.088 0.911 0.001
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.084 0.916 0.000
I42.0 Dilated cardiomyopathy
0.081 0.919 0.000
I72.8 Aneurysm of other specified arteries
0.080 0.920 0.000
E83.1 Disorders of iron metabolism
0.080 0.920 0.000
I13 Hypertensive heart and renal disease
0.078 0.921 0.000
I72.9 Aneurysm of unspecified site
0.078 0.922 0.000
I78.1 Naevus, nonneoplastic
0.078 0.922 0.000
I24.8 Other forms of acute ischaemic heart disease
0.077 0.923 0.000
I72.3 Aneurysm of iliac artery
0.075 0.925 0.000
K83 Other diseases of biliary tract
0.000 0.928 0.072
I72.4 Aneurysm of artery of lower extremity
0.070 0.930 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.070 0.930 0.000
E86 Volume depletion
0.069 0.931 0.000
I27.0 Primary pulmonary hypertension
0.068 0.932 0.000
I35.9 Aortic valve disorder, unspecified
0.068 0.932 0.000
I11 Hypertensive heart disease
0.068 0.932 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.067 0.933 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.067 0.933 0.000
I72.1 Aneurysm of artery of upper extremity
0.067 0.933 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.066 0.934 0.000
I70 Atherosclerosis
0.065 0.935 0.000
I78.9 Disease of capillaries, unspecified
0.064 0.935 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.064 0.936 0.000
I79.1 Aortitis in diseases classified elsewhere
0.060 0.939 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.060 0.939 0.000
I46.0 Cardiac arrest with successful resuscitation
0.058 0.941 0.000
I77 Other disorders of arteries and arterioles
0.058 0.942 0.000
I72.2 Aneurysm of renal artery
0.058 0.942 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.056 0.943 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.056 0.943 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.056 0.943 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.056 0.943 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.055 0.945 0.000
I78.8 Other diseases of capillaries
0.053 0.947 0.000
K83.2 Perforation of bile duct
0.000 0.948 0.052
K83.9 Disease of biliary tract, unspecified
0.000 0.948 0.052
I70.8 Atherosclerosis of other arteries
0.050 0.950 0.000
K83.5 Biliary cyst
0.000 0.952 0.048
I15 Secondary hypertension
0.047 0.952 0.000
I77.8 Other specified disorders of arteries and arterioles
0.047 0.953 0.000
K83.4 Spasm of sphincter of Oddi
0.000 0.953 0.047
I77.0 Arteriovenous fistula, acquired
0.047 0.953 0.000
I70.9 Generalised and unspecified atherosclerosis
0.046 0.954 0.000
I35.8 Other aortic valve disorders
0.045 0.954 0.000
I12 Hypertensive renal disease
0.045 0.955 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.045 0.955 0.000
I73 Other peripheral vascular diseases
0.045 0.955 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.044 0.956 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.043 0.956 0.000
I70.0 Atherosclerosis of aorta
0.043 0.957 0.000
K83.3 Fistula of bile duct
0.000 0.957 0.043
M07.3 Other psoriatic arthropathies
0.042 0.958 0.000
I77.5 Necrosis of artery
0.042 0.958 0.000
I77.4 Coeliac artery compression syndrome
0.042 0.958 0.000
I77.3 Arterial fibromuscular dysplasia
0.042 0.958 0.000
K83.8 Other specified diseases of biliary tract
0.000 0.958 0.042
I70.1 Atherosclerosis of renal artery
0.041 0.959 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.040 0.960 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.039 0.961 0.000
I74 Arterial embolism and thrombosis
0.039 0.961 0.000
I77.1 Stricture of artery
0.038 0.962 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.037 0.963 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.037 0.963 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.036 0.964 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.036 0.964 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.035 0.965 0.000
I72.0 Aneurysm of carotid artery
0.034 0.965 0.001
I15.8 Other secondary hypertension
0.034 0.966 0.000
I15.2 Hypertension secondary to endocrine disorders
0.034 0.966 0.000
I15.0 Renovascular hypertension
0.033 0.967 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.033 0.967 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.033 0.967 0.000
M07.38 Other psoriatic arthropathies (Other)
0.033 0.967 0.000
I77.2 Rupture of artery
0.032 0.967 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.032 0.967 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.032 0.968 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.032 0.968 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.031 0.969 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.031 0.969 0.000
I71 Aortic aneurysm and dissection
0.031 0.969 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.030 0.969 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.030 0.969 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.030 0.969 0.000
I73.8 Other specified peripheral vascular diseases
0.030 0.969 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.030 0.969 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.030 0.970 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.030 0.970 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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