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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2268146
log Bayes Factor = 8.28082
Chromosome 12   position 9,869,271  (GRCh37) Explore rs2268146 on Ensembl!
Variant rs2268146 is part of Cluster X0323

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.002 0.998
E03 Other hypothyroidism
0.000 0.003 0.997
E00-E07 Disorders of thyroid gland
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.004 0.996
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E20-E35 Disorders of other endocrine glands
0.000 0.008 0.992
E10.5 With peripheral circulatory complications
0.000 0.012 0.988
E06 Thyroiditis
0.000 0.053 0.947
E34 Other endocrine disorders
0.000 0.064 0.936
E27 Other disorders of adrenal gland
0.000 0.072 0.928
E06.3 Autoimmune thyroiditis
0.000 0.081 0.919
E10.4 With neurological complications
0.000 0.095 0.905
E34.9 Endocrine disorder, unspecified
0.000 0.112 0.888
E22 Hyperfunction of pituitary gland
0.000 0.130 0.870
E10.8 With unspecified complications
0.000 0.152 0.848
E10.1 With ketoacidosis
0.000 0.158 0.842
E10.2 With renal complications
0.000 0.162 0.838
E20 Hypoparathyroidism
0.000 0.168 0.832
E23 Hypofunction and other disorders of pituitary gland
0.000 0.186 0.814
E10.9 Without complications
0.000 0.192 0.808
E25 Adrenogenital disorders
0.000 0.194 0.806
E27.1 Primary adrenocortical insufficiency
0.000 0.196 0.804
E24 Cushing's syndrome
0.000 0.199 0.801
E27.9 Disorder of adrenal gland, unspecified
0.000 0.204 0.796
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.205 0.795
E07 Other disorders of thyroid
0.000 0.207 0.793
E10.0 With coma
0.000 0.213 0.786
E13 Other specified diabetes mellitus
0.000 0.219 0.781
E23.2 Diabetes insipidus
0.000 0.236 0.764
E22.1 Hyperprolactinaemia
0.000 0.242 0.758
E27.8 Other specified disorders of adrenal gland
0.000 0.244 0.756
E34.0 Carcinoid syndrome
0.000 0.253 0.747
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.277 0.723
E24.9 Cushing's syndrome, unspecified
0.000 0.278 0.722
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.280 0.720
E20.9 Hypoparathyroidism, unspecified
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.285 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.286 0.714
E00 Congenital iodine-deficiency syndrome
0.000 0.286 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.286 0.714
E28 Ovarian dysfunction
0.000 0.288 0.712
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.289 0.711
E32 Diseases of thymus
0.000 0.289 0.711
E30 Disorders of puberty, not elsewhere classified
0.000 0.289 0.711
E06.5 Other chronic thyroiditis
0.000 0.298 0.702
E34.3 Short stature, not elsewhere classified
0.000 0.299 0.701
E07.8 Other specified disorders of thyroid
0.000 0.304 0.696
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.315 0.685
E27.2 Addisonian crisis
0.000 0.317 0.683
E06.1 Subacute thyroiditis
0.000 0.318 0.681
E06.4 Drug-induced thyroiditis
0.000 0.321 0.679
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.321 0.679
E06.0 Acute thyroiditis
0.000 0.321 0.679
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.324 0.676
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.327 0.673
E34.5 Androgen resistance syndrome
0.000 0.329 0.671
E34.4 Constitutional tall stature
0.000 0.329 0.671
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.329 0.671
E34.1 Other hypersecretion of intestinal hormones
0.000 0.329 0.671
E27.5 Adrenomedullary hyperfunction
0.000 0.334 0.666
E27.0 Other adrenocortical overactivity
0.000 0.334 0.666
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.335 0.665
E13.9 Without complications
0.000 0.345 0.655
E31 Polyglandular dysfunction
0.000 0.348 0.652
E03.8 Other specified hypothyroidism
0.000 0.364 0.636
E40-E46 Malnutrition
0.000 0.367 0.633
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.376 0.624
E22.8 Other hyperfunction of pituitary gland
0.000 0.376 0.624
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.379 0.621
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.391 0.609
E29 Testicular dysfunction
0.000 0.394 0.606
E20.8 Other hypoparathyroidism
0.000 0.403 0.597
E20.1 Pseudohypoparathyroidism
0.000 0.403 0.597
E20.0 Idiopathic hypoparathyroidism
0.000 0.403 0.597
E28.3 Primary ovarian failure
0.000 0.405 0.595
E06.9 Thyroiditis, unspecified
0.000 0.415 0.585
E34.8 Other specified endocrine disorders
0.000 0.415 0.584
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.416 0.584
E23.1 Drug-induced hypopituitarism
0.000 0.416 0.584
E25.9 Adrenogenital disorder, unspecified
0.000 0.422 0.578
E25.8 Other adrenogenital disorders
0.000 0.422 0.578
E24.8 Other Cushing's syndrome
0.000 0.426 0.574
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.426 0.574
E24.3 Ectopic ACTH syndrome
0.000 0.426 0.574
E24.1 Nelson's syndrome
0.000 0.426 0.574
E07.1 Dyshormogenetic goitre
0.000 0.432 0.568
E07.0 Hypersecretion of calcitonin
0.000 0.432 0.568
E23.6 Other disorders of pituitary gland
0.000 0.435 0.565
E13.8 With unspecified complications
0.000 0.440 0.560
E13.7 With multiple complications
0.000 0.440 0.560
E13.6 With other specified complications
0.000 0.440 0.560
E13.5 With peripheral circulatory complications
0.000 0.440 0.560
E13.4 With neurological complications
0.000 0.440 0.560
E13.2 With renal complications
0.000 0.440 0.560
E13.1 With ketoacidosis
0.000 0.440 0.560
E13.0 With coma
0.000 0.440 0.560
E22.0 Acromegaly and pituitary gigantism
0.000 0.442 0.558
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.458 0.542
E24.0 Pituitary-dependent Cushing's disease
0.000 0.472 0.528
E03.1 Congenital hypothyroidism without goitre
0.001 0.474 0.525
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.488 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.488 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.488 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.488 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.488 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.488 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.488 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.488 0.512
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E28.9 Ovarian dysfunction, unspecified
0.000 0.489 0.510
E28.8 Other ovarian dysfunction
0.000 0.489 0.510
E28.1 Androgen excess
0.000 0.489 0.510
E28.0 Oestrogen excess
0.000 0.489 0.510
E30.9 Disorder of puberty, unspecified
0.000 0.490 0.510
E30.8 Other disorders of puberty
0.000 0.490 0.510
E30.1 Precocious puberty
0.000 0.490 0.510
E30.0 Delayed puberty
0.000 0.490 0.510
E32.9 Disease of thymus, unspecified
0.000 0.490 0.510
E32.8 Other diseases of thymus
0.000 0.490 0.510
E32.1 Abscess of thymus
0.000 0.490 0.510
E32.0 Persistent hyperplasia of thymus
0.000 0.490 0.510
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.490 0.510
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.490 0.510
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.490 0.510
E13.3 With ophthalmic complications
0.000 0.490 0.509
E26 Hyperaldosteronism
0.000 0.496 0.504
E65-E68 Obesity and other hyperalimentation
0.000 0.497 0.503
E23.0 Hypopituitarism
0.000 0.504 0.496
E21.2 Other hyperparathyroidism
0.000 0.504 0.496
E15 Nondiabetic hypoglycaemic coma
0.000 0.523 0.477
E24.2 Drug-induced Cushing's syndrome
0.000 0.524 0.475
E10.6 With other specified complications
0.001 0.526 0.473
E31.9 Polyglandular dysfunction, unspecified
0.000 0.532 0.467
E31.8 Other polyglandular dysfunction
0.000 0.532 0.467
E31.1 Polyglandular hyperfunction
0.000 0.532 0.467
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.546 0.454
E45 Retarded development following protein-energy malnutrition
0.000 0.546 0.454
E43 Unspecified severe protein-energy malnutrition
0.000 0.546 0.454
E42 Marasmic kwashiorkor
0.000 0.546 0.454
E41 Nutritional marasmus
0.000 0.546 0.454
E40 Kwashiorkor
0.000 0.546 0.454
E07.9 Disorder of thyroid, unspecified
0.000 0.546 0.454
E21.4 Other specified disorders of parathyroid gland
0.000 0.553 0.447
E29.8 Other testicular dysfunction
0.000 0.565 0.434
E29.0 Testicular hyperfunction
0.000 0.565 0.434
E21.3 Hyperparathyroidism, unspecified
0.000 0.570 0.430
E16 Other disorders of pancreatic internal secretion
0.000 0.572 0.427
E23.7 Disorder of pituitary gland, unspecified
0.000 0.576 0.424
E31.0 Autoimmune polyglandular failure
0.000 0.591 0.408
E29.9 Testicular dysfunction, unspecified
0.000 0.596 0.403
E14 Unspecified diabetes mellitus
0.000 0.611 0.389
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.622 0.378
E50-E64 Other nutritional deficiencies
0.000 0.622 0.378
E46 Unspecified protein-energy malnutrition
0.000 0.628 0.372
E29.1 Testicular hypofunction
0.000 0.628 0.371
E28.2 Polycystic ovarian syndrome
0.000 0.634 0.366
E26.8 Other hyperaldosteronism
0.000 0.638 0.361
E26.1 Secondary hyperaldosteronism
0.000 0.638 0.361
E67 Other hyperalimentation
0.000 0.639 0.360
E68 Sequelae of hyperalimentation
0.000 0.639 0.360
E11 Non-insulin-dependent diabetes mellitus
0.000 0.644 0.356
E14.6 With other specified complications
0.000 0.662 0.338
E26.9 Hyperaldosteronism, unspecified
0.001 0.669 0.330
E16.1 Other hypoglycaemia
0.000 0.672 0.328
E44.1 Mild protein-energy malnutrition
0.000 0.674 0.325
E44.0 Moderate protein-energy malnutrition
0.000 0.674 0.325
E66 Obesity
0.000 0.676 0.324
E11.5 With peripheral circulatory complications
0.000 0.677 0.323
E14.2 Withrenal complications
0.000 0.685 0.315
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.693 0.307
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.693 0.307
E16.4 Abnormal secretion of gastrin
0.000 0.693 0.307
E16.3 Increased secretion of glucagon
0.000 0.693 0.307
E14.5 With peripheral circulatory complications
0.000 0.696 0.303
E66.0 Obesity due to excess calories
0.000 0.702 0.298
E11.1 With ketoacidosis
0.000 0.713 0.287
E14.7 With multiple complications
0.000 0.721 0.279
E16.2 Hypoglycaemia, unspecified
0.000 0.721 0.279
E56 Other vitamin deficiencies
0.000 0.723 0.277
E11.6 With other specified complications
0.000 0.728 0.272
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.729 0.271
E50 Vitamin A deficiency
0.000 0.729 0.271
E60 Dietary zinc deficiency
0.000 0.729 0.271
E59 Dietary selenium deficiency
0.000 0.729 0.271
E52 Niacin deficiency [pellagra]
0.000 0.729 0.271
E14.1 With ketoacidosis
0.000 0.731 0.269
E11.2 With renal complications
0.000 0.734 0.266
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.740 0.260
E14.0 With coma
0.000 0.740 0.260
E67.8 Other specified hyperalimentation
0.000 0.741 0.258
E67.3 Hypervitaminosis D
0.000 0.741 0.258
E67.2 Megavitamin-B6 syndrome
0.000 0.741 0.258
E67.1 Hypercarotenaemia
0.000 0.741 0.258
E67.0 Hypervitaminosis A
0.000 0.741 0.258
E61 Deficiency of other nutrient elements
0.000 0.742 0.258
E58 Dietary calcium deficiency
0.000 0.744 0.256
E53 Deficiency of other B group vitamins
0.000 0.744 0.256
E11.7 With multiple complications
0.000 0.745 0.255
E51 Thiamine deficiency
0.000 0.747 0.252
E63 Other nutritional deficiencies
0.000 0.749 0.251
E54 Ascorbic acid deficiency
0.000 0.750 0.250
E14.8 With unspecified complications
0.000 0.755 0.244
E11.0 With coma
0.000 0.759 0.241
E66.1 Drug-induced obesity
0.000 0.768 0.232
E14.4 With neurological complications
0.000 0.774 0.226
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.778 0.222
E65 Localised adiposity
0.000 0.778 0.221
E26.0 Primary hyperaldosteronism
0.001 0.783 0.216
E66.8 Other obesity
0.000 0.794 0.206
E56.1 Deficiency of vitamin K
0.000 0.795 0.205
E53.9 Vitamin B deficiency, unspecified
0.000 0.796 0.204
E56.9 Vitamin deficiency, unspecified
0.000 0.801 0.199
E56.8 Deficiency of other vitamins
0.000 0.801 0.199
E56.0 Deficiency of vitamin E
0.000 0.801 0.199
E50.9 Vitamin A deficiency, unspecified
0.000 0.806 0.194
E50.8 Other manifestations of vitamin A deficiency
0.000 0.806 0.194
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.806 0.194
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.806 0.194
E50.5 Vitamin A deficiency with night blindness
0.000 0.806 0.194
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.806 0.194
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.806 0.194
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.806 0.194
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.806 0.194
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.806 0.194
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.806 0.194
E64.8 Sequelae of other nutritional deficiencies
0.000 0.806 0.194
E64.3 Sequelae of rickets
0.000 0.806 0.194
E64.2 Sequelae of vitamin C deficiency
0.000 0.806 0.194
E64.1 Sequelae of vitamin A deficiency
0.000 0.806 0.194
E64.0 Sequelae of protein-energy malnutrition
0.000 0.806 0.194
E61.9 Deficiency of nutrient element, unspecified
0.000 0.814 0.185
E61.8 Deficiency of other specified nutrient elements
0.000 0.814 0.185
E61.7 Deficiency of multiple nutrient elements
0.000 0.814 0.185
E61.6 Vanadium deficiency
0.000 0.814 0.185
E61.5 Molybdenum deficiency
0.000 0.814 0.185
E61.4 Chromium deficiency
0.000 0.814 0.185
E61.3 Manganese deficiency
0.000 0.814 0.185
E61.0 Copper deficiency
0.000 0.814 0.185
E55 Vitamin D deficiency
0.000 0.816 0.183
E53.1 Pyridoxine deficiency
0.000 0.817 0.183
E53.0 Riboflavin deficiency
0.000 0.817 0.183
E61.1 Iron deficiency
0.000 0.817 0.183
E51.9 Thiamine deficiency, unspecified
0.000 0.819 0.181
E51.8 Other manifestations of thiamine deficiency
0.000 0.819 0.181
E51.1 Beriberi
0.000 0.819 0.181
E11.8 With unspecified complications
0.000 0.819 0.181
E63.8 Other specified nutritional deficiencies
0.000 0.820 0.180
E63.1 Imbalance of constituents of food intake
0.000 0.820 0.180
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.820 0.180
E61.2 Magnesium deficiency
0.000 0.824 0.176
E11.4 With neurological complications
0.000 0.826 0.174
E51.2 Wernicke's encephalopathy
0.000 0.837 0.163
E63.9 Nutritional deficiency, unspecified
0.000 0.840 0.160
E53.8 Deficiency of other specified B group vitamins
0.000 0.868 0.132
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.868 0.132
E55.0 Rickets, active
0.000 0.868 0.132
E14.3 With ophthalmic complications
0.000 0.880 0.120
E14.9 Without complications
0.000 0.904 0.096
E05.5 Thyroid crisis or storm
0.000 0.905 0.095
E05.4 Thyrotoxicosis factitia
0.000 0.905 0.095
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.905 0.095
E11.9 Without complications
0.000 0.908 0.092
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.910 0.090
E04 Other non-toxic goitre
0.000 0.917 0.083
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.924 0.076
E21.0 Primary hyperparathyroidism
0.000 0.927 0.073
E05.8 Other thyrotoxicosis
0.000 0.935 0.064
E11.3 With ophthalmic complications
0.000 0.938 0.062
E04.8 Other specified non-toxic goitre
0.000 0.940 0.060
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.943 0.057
E04.0 Non-toxic diffuse goitre
0.000 0.946 0.053
E55.9 Vitamin D deficiency, unspecified
0.000 0.955 0.044
E04.2 Non-toxic multinodular goitre
0.000 0.969 0.031
E05.9 Thyrotoxicosis, unspecified
0.000 0.969 0.031
N75.0 Cyst of Bartholin's gland
0.000 0.986 0.014
E04.9 Non-toxic goitre, unspecified
0.000 0.988 0.011
E66.9 Obesity, unspecified
0.000 0.991 0.009
R80 Isolated proteinuria
0.009 0.991 0.000
Z37.2 Twins, both liveborn
0.000 0.992 0.008
E04.1 Non-toxic single thyroid nodule
0.001 0.993 0.005
D12.6 Colon, unspecified
0.000 0.993 0.007
E70-E90 Metabolic disorders
0.000 0.994 0.006
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.006 0.994 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.006 0.994 0.000
C45.0 Mesothelioma of pleura
0.000 0.994 0.006
Z63.8 Other specified problems related to primary support group
0.006 0.994 0.000
E85 Amyloidosis
0.000 0.994 0.006
F41.9 Anxiety disorder, unspecified
0.006 0.994 0.000
O30.0 Twin pregnancy
0.000 0.994 0.006
S05 Injury of eye and orbit
0.005 0.995 0.000
R54 Senility
0.005 0.995 0.000
S05.1 Contusion of eyeball and orbital tissues
0.005 0.995 0.000
C45 Mesothelioma
0.000 0.995 0.005
M54.9 Dorsalgia, unspecified
0.005 0.995 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.995 0.005
S05.9 Injury of eye and orbit, part unspecified
0.005 0.995 0.000
E84 Cystic fibrosis
0.000 0.995 0.005
E70 Disorders of aromatic amino-acid metabolism
0.000 0.995 0.005
E85.4 Organ-limited amyloidosis
0.000 0.995 0.005
C45.9 Mesothelioma, unspecified
0.000 0.995 0.005
S01.7 Multiple open wounds of head
0.000 0.995 0.005
S05.6 Penetrating wound of eyeball without foreign body
0.005 0.995 0.000
E77 Disorders of glycoprotein metabolism
0.000 0.995 0.005
E76 Disorders of glycosaminoglycan metabolism
0.000 0.995 0.005
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.995 0.005
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.995 0.005
M54.94 Dorsalgia, unspecified (Thoracic region)
0.005 0.995 0.000
E85.8 Other amyloidosis
0.000 0.995 0.004
Z63.7 Other stressful life events affecting family and household
0.005 0.995 0.000
E85.3 Secondary systemic amyloidosis
0.000 0.995 0.004
O14.1 Severe preeclampsia
0.000 0.996 0.004
E74 Other disorders of carbohydrate metabolism
0.000 0.996 0.004
K51.2 Ulcerative (chronic) proctitis
0.000 0.996 0.004
E79 Disorders of purine and pyrimidine metabolism
0.000 0.996 0.004
Z63 Other problems related to primary support group, including family circumstances
0.004 0.996 0.000
C45.7 Mesothelioma of other sites
0.000 0.996 0.004
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.004 0.996 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.004 0.996 0.000
E72 Other disorders of amino-acid metabolism
0.000 0.996 0.004
S65.1 Injury of radial artery at wrist and hand level
0.004 0.996 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.996 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.996 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.996 0.004
E75.5 Other lipid storage disorders
0.000 0.996 0.004
S05.4 Penetrating wound of orbit with or without foreign body
0.004 0.996 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.996 0.004
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.004 0.996 0.000
S05.8 Other injuries of eye and orbit
0.004 0.996 0.000
M54.1 Radiculopathy
0.004 0.996 0.000
S05.7 Avulsion of eye
0.004 0.996 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.004 0.996 0.000
E70.3 Albinism
0.000 0.996 0.004
M54.92 Dorsalgia, unspecified (Cervical region)
0.004 0.996 0.000
S65.5 Injury of blood vessel(s) of other finger
0.004 0.996 0.000
S65 Injury of blood vessels at wrist and hand level
0.004 0.996 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.004 0.996 0.000
M54.14 Radiculopathy (Thoracic region)
0.004 0.996 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.004 0.996 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.004 0.996 0.000
C45.2 Mesothelioma of pericardium
0.000 0.996 0.004
C45.1 Mesothelioma of peritoneum
0.000 0.996 0.004
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.004 0.996 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.004 0.996 0.000
E75.6 Lipid storage disorder, unspecified
0.000 0.996 0.004
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.996 0.004
E75.3 Sphingolipidosis, unspecified
0.000 0.996 0.004
E75.2 Other sphingolipidosis
0.000 0.996 0.004
E75.1 Other gangliosidosis
0.000 0.996 0.004
E75.0 GM2 gangliosidosis
0.000 0.996 0.004
E84.8 Cystic fibrosis with other manifestations
0.000 0.996 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.996 0.004
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.996 0.004
E85.9 Amyloidosis, unspecified
0.000 0.996 0.004
Z63.6 Dependent relative needing care at home
0.004 0.996 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.004 0.996 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.996 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.996 0.004
E70.2 Disorders of tyrosine metabolism
0.000 0.996 0.004
E70.1 Other hyperphenylalaninaemias
0.000 0.996 0.004
E70.0 Classical phenylketonuria
0.000 0.996 0.004
S91.1 Open wound of toe(s) without damage to nail
0.000 0.996 0.004
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.996 0.004
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.004 0.996 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.004 0.996 0.000
E71.3 Disorders of fatty-acid metabolism
0.000 0.996 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.996 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.996 0.003
E71.0 Maple-syrup-urine disease
0.000 0.996 0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.996 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.996 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.996 0.003
E76.2 Other mucopolysaccharidoses
0.000 0.996 0.003
E76.1 Mucopolysaccharidosis, type II
0.000 0.996 0.003
E76.0 Mucopolysaccharidosis, type I
0.000 0.996 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.996 0.003
E77.8 Other disorders of glycoprotein metabolism
0.000 0.996 0.003
E77.1 Defects in glycoprotein degradation
0.000 0.996 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.996 0.003
K11.8 Other diseases of salivary glands
0.004 0.996 0.000
E74.0 Glycogen storage disease
0.000 0.996 0.003
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.004 0.996 0.000
E73 Lactose intolerance
0.000 0.996 0.003
M54 Dorsalgia
0.004 0.996 0.000
M54.6 Pain in thoracic spine
0.003 0.996 0.000
S01.3 Open wound of ear
0.004 0.996 0.000
E88 Other metabolic disorders
0.000 0.996 0.004
S62.20 Fracture of first metacarpal bone (closed)
0.003 0.996 0.000
S65.4 Injury of blood vessel(s) of thumb
0.003 0.996 0.000
M54.36 Sciatica (Lumbar region)
0.003 0.996 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.997 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.997 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.997 0.003
E74.2 Disorders of galactose metabolism
0.000 0.997 0.003
E74.1 Disorders of fructose metabolism
0.000 0.997 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.997 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.997 0.003
E79.1 Lesch-Nyhan syndrome
0.000 0.997 0.003
Z63.9 Problem related to primary support group, unspecified
0.003 0.997 0.000
Z63.5 Disruption of family by separation and divorce
0.003 0.997 0.000
Z63.3 Absence of family member
0.003 0.997 0.000
Z63.2 Inadequate family support
0.003 0.997 0.000
Z63.1 Problems in relationship with parents and in-laws
0.003 0.997 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.003 0.997 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.997 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.997 0.003
E72.5 Disorders of glycine metabolism
0.000 0.997 0.003
E72.4 Disorders of ornithine metabolism
0.000 0.997 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.997 0.003
E72.2 Disorders of urea cycle metabolism
0.000 0.997 0.003
Z63.4 Disappearance and death of family member
0.003 0.997 0.000
M54.3 Sciatica
0.003 0.997 0.000
E72.0 Disorders of amino-acid transport
0.000 0.997 0.003
E80.2 Other porphyria
0.000 0.997 0.003
F45.8 Other somatoform disorders
0.003 0.997 0.000
E80.1 Porphyria cutanea tarda
0.000 0.997 0.003
L71.9 Rosacea, unspecified
0.003 0.997 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.997 0.003
E83.3 Disorders of phosphorus metabolism
0.000 0.997 0.003
M54.15 Radiculopathy (Thoracolumbar region)
0.003 0.997 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.003 0.997 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.003 0.997 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.997 0.003
S65.9 Injury of unspecified blood vessel at wrist and hand level
0.003 0.997 0.000
S65.8 Injury of other blood vessels at wrist and hand level
0.003 0.997 0.000
S65.7 Injury of multiple blood vessels at wrist and hand level
0.003 0.997 0.000
S65.3 Injury of deep palmar arch
0.003 0.997 0.000
S65.2 Injury of superficial palmar arch
0.003 0.997 0.000
S65.0 Injury of ulnar artery at wrist and hand level
0.003 0.997 0.000
M54.19 Radiculopathy (Site unspecified)
0.003 0.997 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.997 0.003
M54.12 Radiculopathy (Cervical region)
0.003 0.997 0.000
Z04.9 Examination and observation for unspecified reason
0.003 0.997 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.997 0.003
O46.9 Antepartum haemorrhage, unspecified
0.000 0.997 0.003
S62.40 Multiple fractures of metacarpal bones (closed)
0.003 0.997 0.000
Z63.0 Problems in relationship with spouse or partner
0.003 0.997 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.997 0.003
E80.5 Crigler-Najjar syndrome
0.000 0.997 0.003
E80.3 Defects of catalase and peroxydase
0.000 0.997 0.003
E80.0 Hereditary erythropoietic porphyria
0.000 0.997 0.003
S62.2 Fracture of first metacarpal bone
0.003 0.997 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.997 0.003
E83 Disorders of mineral metabolism
0.000 0.997 0.003
E88.3 Tumour lysis syndrome
0.000 0.997 0.003
M79.54 Residual foreign body in soft tissue (Hand)
0.000 0.997 0.003
M54.16 Radiculopathy (Lumbar region)
0.003 0.997 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.003 0.997 0.000
E73.8 Other lactose intolerance
0.000 0.997 0.002
E73.1 Secondary lactase deficiency
0.000 0.997 0.002
E73.0 Congenital lactase deficiency
0.000 0.997 0.002
L71.8 Other rosacea
0.003 0.997 0.000
M54.69 Pain in thoracic spine-Site unspe
0.003 0.997 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.003 0.997 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.003 0.997 0.000
M54.66 Pain in thoracic spine-Lumbar
0.003 0.997 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.003 0.997 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.003 0.997 0.000
M54.62 Pain in thoracic spine-Cervical
0.003 0.997 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.003 0.997 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.003 0.997 0.000
M54.0 Panniculitis affecting regions of neck and back
0.003 0.997 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.997 0.003
O30 Multiple gestation
0.000 0.997 0.003
R82 Other abnormal findings in urine
0.003 0.997 0.000
M54.8 Other dorsalgia
0.003 0.997 0.000
S62.4 Multiple fractures of metacarpal bones
0.003 0.997 0.000
E80.6 Other disorders of bilirubin metabolism
0.000 0.997 0.002
H52.3 Anisometropia and aniseikonia
0.000 0.997 0.003
S62.71 Multiple fractures of fingers (open)
0.003 0.997 0.000
N75 Diseases of Bartholin's gland
0.000 0.997 0.003
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.997 0.003
S62.7 Multiple fractures of fingers
0.003 0.997 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.000 0.997 0.003
M54.35 Sciatica (Thoracolumbar region)
0.003 0.997 0.000
M54.34 Sciatica-Thoracic
0.003 0.997 0.000
M54.33 Sciatica-Cervicothoracic
0.003 0.997 0.000
M54.32 Sciatica-Cervical
0.003 0.997 0.000
M54.31 Sciatica-Occipit-atl-axl
0.003 0.997 0.000
L71 Rosacea
0.003 0.997 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.997 0.003
A04.8 Other specified bacterial intestinal infections
0.000 0.997 0.003
L71.1 Rhinophyma
0.003 0.997 0.000
H26.2 Complicated cataract
0.000 0.997 0.003
S62 Fracture at wrist and hand level
0.003 0.997 0.000
M54.30 Sciatica (Multiple sites in spine)
0.002 0.997 0.000
M22.4 Chondromalacia patellae
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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