TreeWAS – Variant ID: rs2273565

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	1.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.999	0.001
L40.9 Psoriasis, unspecified	0.998	0.002
C15-C26 Malignant neoplasms of digestive organs	0.997	0.003
C78.7 Secondary malignant neoplasm of liver	0.996	0.004
C44.3 Skin of other and unspecified parts of face	0.990	0.010
L40 Psoriasis	0.989	0.011
L40-L45 Papulosquamous disorders	0.977	0.023
C44.1 Skin of eyelid, including canthus	0.974	0.026
C78.0 Secondary malignant neoplasm of lung	0.971	0.029
C19 Malignant neoplasm of rectosigmoid junction	0.970	0.030
Chapter XII Diseases of the skin and subcutaneous tissue	0.969	0.031
# Top node	0.967	0.033
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.962	0.038
Chapter V Mental and behavioural disorders	0.961	0.039
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.959	0.041
F30-F39 Mood [affective] disorders	0.958	0.042
Chapter VII Diseases of the eye and adnexa	0.955	0.045
C18 Malignant neoplasm of colon	0.953	0.047
M45-M49 Spondylopathies	0.952	0.048
M47 Spondylosis	0.945	0.055
M47.8 Other spondylosis	0.939	0.061
H53-H54 Visual disturbances and blindness	0.938	0.062
F31 Bipolar affective disorder	0.937	0.063
M47.82 Other spondylosis (Cervical region)	0.927	0.073
M50-M54 Other dorsopathies	0.922	0.078
C44.2 Skin of ear and external auricular canal	0.921	0.079
D00-D09 In situ neoplasms	0.919	0.081
L60-L75 Disorders of skin appendages	0.914	0.086
H54 Blindness and low vision	0.911	0.089
C44.4 Skin of scalp and neck	0.903	0.097
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.901	0.099
C77.2 Intra-abdominal lymph nodes	0.899	0.101
C44.5 Skin of trunk	0.890	0.110
F30 Manic episode	0.882	0.118
C18.9 Colon, unspecified	0.875	0.125
L72 Follicular cysts of skin and subcutaneous tissue	0.857	0.143
H30-H36 Disorders of choroid and retina	0.854	0.146
M50 Cervical disk disorders	0.853	0.147
H54.0 Blindness, both eyes	0.851	0.149
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.850	0.150
M54 Dorsalgia	0.848	0.152
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.843	0.157
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.840	0.159
C15 Malignant neoplasm of oesophagus	0.840	0.160
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.840	0.160
C71 Malignant neoplasm of brain	0.831	0.169
D03 Melanoma in situ	0.826	0.174
F99-F99 Unspecified mental disorder	0.826	0.174
M50.3 Other cervical disk degeneration	0.820	0.180
C17 Malignant neoplasm of small intestine	0.818	0.182
M54.5 Low back pain	0.816	0.184
L40.0 Psoriasis vulgaris	0.816	0.184
H53 Visual disturbances	0.812	0.188
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.808	0.192
M70-M79 Other soft tissue disorders	0.806	0.194
C43 Malignant melanoma of skin	0.806	0.194
M47.89 Other spondylosis (Site unspecified)	0.802	0.198
C77.1 Intrathoracic lymph nodes	0.800	0.199
F31.0 Bipolar affective disorder, current episode hypomanic	0.798	0.202
D05 Carcinoma in situ of breast	0.798	0.202
C78.4 Secondary malignant neoplasm of small intestine	0.796	0.203
C18.6 Descending colon	0.791	0.209
F39 Unspecified mood [affective] disorder	0.788	0.212
L72.1 Trichilemmal cyst	0.788	0.212
M86-M90 Other osteopathies	0.787	0.213
F31.9 Bipolar affective disorder, unspecified	0.786	0.214
H54.7 Unspecified visual loss	0.784	0.216
C18.3 Hepatic flexure	0.782	0.218
C78.1 Secondary malignant neoplasm of mediastinum	0.780	0.220
M54.56 Low back pain (Lumbar region)	0.780	0.220
H46-H48 Disorders of optic nerve and visual pathways	0.779	0.221
H10-H13 Disorders of conjunctiva	0.778	0.222
M00-M03 Infectious arthropathies	0.775	0.225
C77.0 Lymph nodes of head, face and neck	0.771	0.229
M46 Other inflammatory spondylopathies	0.769	0.231
M47.87 Other spondylosis (Lumbosacral region)	0.766	0.234
L40.5 Arthropathic psoriasis	0.766	0.234
L57 Skin changes due to chronic exposure to nonionising radiation	0.765	0.235
H35 Other retinal disorders	0.762	0.238
C18.8 Overlapping lesion of colon	0.760	0.240
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.760	0.240
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.759	0.241
C25 Malignant neoplasm of pancreas	0.755	0.245
M77 Other enthesopathies	0.753	0.247
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.753	0.247
F32 Depressive episode	0.753	0.247
L71 Rosacea	0.748	0.252
F52 Sexual dysfunction, not caused by organic disorder or disease	0.747	0.252
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.747	0.253
C44.0 Skin of lip	0.747	0.253
H53.0 Amblyopia ex anopsia	0.745	0.255
H18 Other disorders of cornea	0.745	0.255
L70 Acne	0.744	0.255
F80-F89 Disorders of psychological development	0.744	0.256
H53.4 Visual field defects	0.743	0.257
C18.7 Sigmoid colon	0.743	0.257
C51-C58 Malignant neoplasms of female genital organs	0.743	0.257
F30.0 Hypomania	0.741	0.258
M60-M63 Disorders of muscles	0.741	0.259
M91-M94 Chondropathies	0.739	0.261
C44.7 Skin of lower limb, including hip	0.739	0.261
H35.3 Degeneration of macula and posterior pole	0.737	0.263
D03.5 Melanoma in situ of trunk	0.737	0.263
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.736	0.264
C71.1 Frontal lobe	0.733	0.267
C77.3 Axillary and upper limb lymph nodes	0.732	0.268
F30.2 Mania with psychotic symptoms	0.732	0.268
C77.9 Lymph node, unspecified	0.731	0.269
C64-C68 Malignant neoplasms of urinary tract	0.730	0.270
M54.1 Radiculopathy	0.729	0.271
F99 Mental disorder, not otherwise specified	0.729	0.271
C43.5 Malignant melanoma of trunk	0.728	0.272
M40-M43 Deforming dorsopathies	0.724	0.276
F33 Recurrent depressive disorder	0.720	0.280
F30.9 Manic episode, unspecified	0.720	0.280
M47.2 Other spondylosis with radiculopathy	0.718	0.282
C44.9 Malignant neoplasm of skin, unspecified	0.718	0.282
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.718	0.282
L50-L54 Urticaria and erythema	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C44.8 Overlapping lesion of skin	0.717	0.283
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.716	0.284
C23 Malignant neoplasm of gallbladder	0.715	0.285
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.715	0.285
D05.1 Intraductal carcinoma in situ	0.714	0.286
C18.5 Splenic flexure	0.714	0.286
M54.59 Low back pain (Site unspecified)	0.713	0.287
H54.9 Unspecified visual impairment (binocular)	0.713	0.287
L57.0 Actinic keratosis	0.711	0.289
L40.8 Other psoriasis	0.709	0.291
L40.4 Guttate psoriasis	0.709	0.291
L40.3 Pustulosis palmaris et plantaris	0.709	0.291
L40.2 Acrodermatitis continua	0.709	0.291
L40.1 Generalised pustular psoriasis	0.709	0.291
D04 Carcinoma in situ of skin	0.707	0.293
C78.2 Secondary malignant neoplasm of pleura	0.704	0.296
H54.4 Blindness, one eye	0.702	0.298
M47.80 Other spondylosis (Multiple sites in spine)	0.700	0.300
L44 Other papulosquamous disorders	0.700	0.300
L41 Parapsoriasis	0.700	0.300
L45 Papulosquamous disorders in diseases classified elsewhere	0.700	0.300
L42 Pityriasis rosea	0.700	0.300
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.699	0.301
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.698	0.301
H34 Retinal vascular occlusions	0.698	0.302
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.696	0.304
H33 Retinal detachments and breaks	0.696	0.304
L10-L14 Bullous disorders	0.695	0.305
M49 Spondylopathies in diseases classified elsewhere	0.695	0.305
M50.2 Other cervical disk displacement	0.694	0.306
Chapter XVI Certain conditions originating in the perinatal period	0.693	0.307
C26 Malignant neoplasm of other and ill-defined digestive organs	0.690	0.310
C17.0 Duodenum	0.689	0.311
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.689	0.311
F70-F79 Mental retardation	0.689	0.311
M47.9 Spondylosis, unspecified	0.688	0.312
F38 Other mood [affective] disorders	0.687	0.313
F34 Persistent mood [affective] disorders	0.687	0.313
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.687	0.313
M77.1 Lateral epicondylitis	0.684	0.316
C18.1 Appendix	0.683	0.316
C77.8 Lymph nodes of multiple regions	0.682	0.318
F52.2 Failure of genital response	0.681	0.319
H47 Other disorders of optic [2nd] nerve and visual pathways	0.680	0.320
D03.6 Melanoma in situ of upper limb, including shoulder	0.679	0.321
C15.5 Lower third of oesophagus	0.679	0.321
M79 Other soft tissue disorders, not elsewhere classified	0.678	0.322
M47.0 Anterior spinal and vertebral artery compression syndromes	0.677	0.323
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.673	0.327
M47.85 Other spondylosis (Thoracolumbar region)	0.673	0.327
M47.84 Other spondylosis (Thoracic region)	0.673	0.327
M47.83 Other spondylosis (Cervicothoracic region)	0.673	0.327
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.673	0.327
F31.8 Other bipolar affective disorders	0.671	0.328
F31.7 Bipolar affective disorder, currently in remission	0.671	0.328
F31.6 Bipolar affective disorder, current episode mixed	0.671	0.328
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.671	0.328
C43.9 Malignant melanoma of skin, unspecified	0.671	0.329
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.670	0.330
D02 Carcinoma in situ of middle ear and respiratory system	0.669	0.331
F60-F69 Disorders of adult personality and behaviour	0.668	0.332
M53 Other dorsopathies, not elsewhere classified	0.668	0.332
H17 Corneal scars and opacities	0.664	0.336
C18.4 Transverse colon	0.663	0.337
D01 Carcinoma in situ of other and unspecified digestive organs	0.659	0.341
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.659	0.341
C71.8 Overlapping lesion of brain	0.657	0.343
M54.12 Radiculopathy (Cervical region)	0.656	0.344
L75 Apocrine sweat disorders	0.655	0.345
L74 Eccrine sweat disorders	0.655	0.345
L68 Hypertrichosis	0.655	0.345
L67 Hair colour and hair shaft abnormalities	0.655	0.345
L66 Cicatricial alopecia [scarring hair loss]	0.655	0.345
L64 Androgenic alopecia	0.655	0.345
L63 Alopecia areata	0.655	0.345
L62 Nail disorders in diseases classified elsewhere	0.655	0.345
H54.6 Unqualified visual loss, one eye	0.653	0.346
H54.5 Low vision, one eye	0.653	0.346
H54.3 Unqualified visual loss, both eyes	0.653	0.346
H54.2 Low vision, both eyes	0.653	0.346
H54.1 Blindness, one eye, low vision, other eye	0.653	0.346
M47.1 Other spondylosis with myelopathy	0.653	0.347
C22.1 Intrahepatic bile duct carcinoma	0.653	0.347
C44.6 Skin of upper limb, including shoulder	0.651	0.349
C16 Malignant neoplasm of stomach	0.648	0.352
C15.9 Oesophagus, unspecified	0.648	0.352
H11 Other disorders of conjunctiva	0.647	0.352
C80 Malignant neoplasm without specification of site	0.647	0.353
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.647	0.353
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.646	0.354
C70 Malignant neoplasm of meninges	0.646	0.354
C69 Malignant neoplasm of eye and adnexa	0.645	0.355
Chapter XXII Codes for special purposes	0.645	0.355
H21 Other disorders of iris and ciliary body	0.645	0.355
C71.0 Cerebrum, except lobes and ventricles	0.644	0.356
C21 Malignant neoplasm of anus and anal canal	0.644	0.356
F40-F48 Neurotic, stress-related and somatoform disorders	0.642	0.358
M00 Pyogenic arthritis	0.642	0.358
M47.86 Other spondylosis (Lumbar region)	0.641	0.359
C18.0 Caecum	0.641	0.359
C43.3 Malignant melanoma of other and unspecified parts of face	0.640	0.360
M48 Other spondylopathies	0.638	0.362
M46.9 Inflammatory spondylopathy, unspecified	0.638	0.362
F32.0 Mild depressive episode	0.637	0.363
L65 Other nonscarring hair loss	0.637	0.363
C15.4 Middle third of oesophagus	0.635	0.364
M77.12 Lateral epicondylitis (Upper arm)	0.635	0.365
H18.9 Disorder of cornea, unspecified	0.635	0.365
M89 Other disorders of bone	0.635	0.365
F30.8 Other manic episodes	0.632	0.368
F30.1 Mania without psychotic symptoms	0.632	0.368
L43 Lichen planus	0.631	0.369
M87 Osteonecrosis	0.630	0.370
L71.9 Rosacea, unspecified	0.629	0.371
D09 Carcinoma in situ of other and unspecified sites	0.628	0.372
C71.2 Temporal lobe	0.626	0.374
M45 Ankylosing spondylitis	0.626	0.374
M76 Enthesopathies of lower limb, excluding foot	0.625	0.375
H50 Other strabismus	0.624	0.376
F32.3 Severe depressive episode with psychotic symptoms	0.623	0.377
L70.0 Acne vulgaris	0.623	0.377
F50 Eating disorders	0.620	0.380
C22.9 Liver, unspecified	0.619	0.380
C77.4 Inguinal and lower limb lymph nodes	0.619	0.381
M90 Osteopathies in diseases classified elsewhere	0.617	0.382
D03.4 Melanoma in situ of scalp and neck	0.617	0.383
L72.2 Steatocystoma multiplex	0.615	0.385
H55-H59 Other disorders of eye and adnexa	0.612	0.388
H32 Chorioretinal disorders in diseases classified elsewhere	0.612	0.388
H30 Chorioretinal inflammation	0.612	0.388
M50.9 Cervical disk disorder, unspecified	0.612	0.388
M50.8 Other cervical disk disorders	0.612	0.388
M80-M85 Disorders of bone density and structure	0.610	0.390
H53.1 Subjective visual disturbances	0.610	0.390
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.610	0.390
C53 Malignant neoplasm of cervix uteri	0.610	0.390
D06 Carcinoma in situ of cervix uteri	0.610	0.390
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.610	0.390
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.609	0.390
L58 Radiodermatitis	0.609	0.390
L56 Other acute skin changes due to ultraviolet radiation	0.609	0.390
L55 Sunburn	0.609	0.390
L60 Nail disorders	0.609	0.390
H35.5 Hereditary retinal dystrophy	0.609	0.391
M54.8 Other dorsalgia	0.608	0.392
M54.0 Panniculitis affecting regions of neck and back	0.608	0.392
M77.0 Medial epicondylitis	0.607	0.393
M54.9 Dorsalgia, unspecified	0.606	0.394
H35.4 Peripheral retinal degeneration	0.603	0.397
H33.5 Other retinal detachments	0.603	0.397
H31 Other disorders of choroid	0.603	0.397
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.603	0.397
F51 Nonorganic sleep disorders	0.603	0.397
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.603	0.397
F55 Abuse of non-dependence-producing substances	0.603	0.397
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.603	0.397
M54.50 Low back pain (Multiple sites in spine)	0.603	0.397
C15.8 Overlapping lesion of oesophagus	0.602	0.398
C15.3 Upper third of oesophagus	0.602	0.398
C15.2 Abdominal part of oesophagus	0.602	0.398
C15.1 Thoracic part of oesophagus	0.602	0.398
C15.0 Cervical part of oesophagus	0.602	0.398
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.602	0.398
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.602	0.398
H15 Disorders of sclera	0.602	0.398
M94 Other disorders of cartilage	0.600	0.400
H18.6 Keratoconus	0.600	0.400
C71.9 Brain, unspecified	0.599	0.401
C71.7 Brain stem	0.596	0.404
C71.6 Cerebellum	0.596	0.404
C71.5 Cerebral ventricle	0.596	0.404
C71.4 Occipital lobe	0.596	0.404
M79.2 Neuralgia and neuritis, unspecified	0.596	0.404
D05.9 Carcinoma in situ of breast, unspecified	0.594	0.406
H40-H42 Glaucoma	0.593	0.407
D03.9 Melanoma in situ, unspecified	0.592	0.408
D03.8 Melanoma in situ of other sites	0.592	0.408
D03.2 Melanoma in situ of ear and external auricular canal	0.592	0.408
D03.1 Melanoma in situ of eyelid, including canthus	0.592	0.408
D03.0 Melanoma in situ of lip	0.592	0.408
C25.0 Head of pancreas	0.592	0.408
C71.3 Parietal lobe	0.591	0.409
C77.5 Intrapelvic lymph nodes	0.589	0.411
H20 Iridocyclitis	0.588	0.412
C17.9 Small intestine, unspecified	0.586	0.414
C17.8 Overlapping lesion of small intestine	0.586	0.414
C17.3 Meckel's diverticulum	0.586	0.414
C17.2 Ileum	0.586	0.414
C17.1 Jejunum	0.586	0.414
F23 Acute and transient psychotic disorders	0.585	0.415
C54 Malignant neoplasm of corpus uteri	0.585	0.415
M54.55 Low back pain (Thoracolumbar region)	0.585	0.415
M54.54 Low back pain-Thoracic	0.585	0.415
M54.53 Low back pain-Cervicothoracic	0.585	0.415
M54.52 Low back pain-Cervical	0.585	0.415
M54.51 Low back pain-Occipit-atl-axl	0.585	0.415
C67 Malignant neoplasm of bladder	0.585	0.415
H47.2 Optic atrophy	0.585	0.415
H18.1 Bullous keratopathy	0.584	0.416
D07 Carcinoma in situ of other and unspecified genital organs	0.583	0.417
C43.4 Malignant melanoma of scalp and neck	0.583	0.417
M62 Other disorders of muscle	0.583	0.417
H53.6 Night blindness	0.582	0.418
H53.5 Colour vision deficiencies	0.582	0.418
H53.3 Other disorders of binocular vision	0.582	0.418
M71 Other bursopathies	0.580	0.420
C22.7 Other specified carcinomas of liver	0.579	0.420
C22.4 Other sarcomas of liver	0.579	0.420
C22.3 Angiosarcoma of liver	0.579	0.420
C22.2 Hepatoblastoma	0.579	0.420
M73 Soft tissue disorders in diseases classified elsewhere	0.578	0.422
F81 Specific developmental disorders of scholastic skills	0.578	0.422
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.578	0.422
D03.3 Melanoma in situ of other and unspecified parts of face	0.578	0.422
C43.8 Overlapping malignant melanoma of skin	0.578	0.422
C43.2 Malignant melanoma of ear and external auricular canal	0.578	0.422
C43.1 Malignant melanoma of eyelid, including canthus	0.578	0.422
C43.0 Malignant melanoma of lip	0.578	0.422
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.576	0.424
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.574	0.426
H34.2 Other retinal artery occlusions	0.574	0.426
C24.1 Ampulla of Vater	0.573	0.426
D05.7 Other carcinoma in situ of breast	0.572	0.428
F32.2 Severe depressive episode without psychotic symptoms	0.571	0.429
H11.3 Conjunctival haemorrhage	0.571	0.429
H18.2 Other corneal oedema	0.570	0.430
C22.0 Liver cell carcinoma	0.568	0.432
H53.2 Diplopia	0.567	0.433
C25.1 Body of pancreas	0.567	0.433
L73 Other follicular disorders	0.567	0.433
H49 Paralytic strabismus	0.566	0.434
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.566	0.434
M41 Scoliosis	0.566	0.434
H10 Conjunctivitis	0.564	0.435
M77.9 Enthesopathy, unspecified	0.563	0.437
M54.6 Pain in thoracic spine	0.561	0.438
F32.1 Moderate depressive episode	0.561	0.439
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.561	0.439
L72.0 Epidermal cyst	0.559	0.441
F84 Pervasive developmental disorders	0.559	0.441
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.558	0.442
H13 Disorders of conjunctiva in diseases classified elsewhere	0.558	0.442
F33.1 Recurrent depressive disorder, current episode moderate	0.556	0.444
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.556	0.444
M02 Reactive arthropathies	0.556	0.444
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.556	0.444
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.556	0.444
M77.5 Other enthesopathy of foot	0.555	0.445
M54.16 Radiculopathy (Lumbar region)	0.555	0.445
C32 Malignant neoplasm of larynx	0.554	0.446
M54.2 Cervicalgia	0.553	0.447
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.552	0.448
M46.8 Other specified inflammatory spondylopathies	0.551	0.449
M46.5 Other infective spondylopathies	0.551	0.449
M46.4 Discitis, unspecified	0.551	0.449
M46.3 Infection of intervertebral disk (pyogenic)	0.551	0.449
M46.2 Osteomyelitis of vertebra	0.551	0.449
M46.1 Sacro-iliitis, not elsewhere classified	0.551	0.449
M46.0 Spinal enthesopathy	0.551	0.449
M65-M68 Disorders of synovium and tendon	0.550	0.450
M47.99 Spondylosis, unspecified (Site unspecified)	0.549	0.451
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.548	0.452
L57.5 Actinic granuloma	0.548	0.452
L57.4 Cutis laxa senilis	0.548	0.452
L57.3 Poikiloderma of Civatte	0.548	0.452
L57.2 Cutis rhomboidalis nuchae	0.548	0.452
L57.1 Actinic reticuloid	0.548	0.452
M77.4 Metatarsalgia	0.547	0.452
M00.9 Pyogenic arthritis, unspecified	0.546	0.454
H35.6 Retinal haemorrhage	0.546	0.454
H35.2 Other proliferative retinopathy	0.546	0.454
H35.1 Retinopathy of prematurity	0.546	0.454
C24.0 Extrahepatic bile duct	0.546	0.454
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.545	0.455
M99 Biomechanical lesions, not elsewhere classified	0.545	0.455
H25-H28 Disorders of lens	0.544	0.456
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.544	0.456
F41 Other anxiety disorders	0.544	0.456
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.542	0.457
C25.8 Overlapping lesion of pancreas	0.541	0.459
C25.7 Other parts of pancreas	0.541	0.459
C25.4 Endocrine pancreas	0.541	0.459
C25.3 Pancreatic duct	0.541	0.459
C25.2 Tail of pancreas	0.541	0.459
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.541	0.459
M77.8 Other enthesopathies, not elsewhere classified	0.540	0.460
M77.3 Calcaneal spur	0.540	0.460
M77.2 Periarthritis of wrist	0.540	0.460
C24.9 Biliary tract, unspecified	0.540	0.460
C24.8 Overlapping lesion of biliary tract	0.540	0.460
F32.8 Other depressive episodes	0.540	0.460
M51 Other intervertebral disk disorders	0.539	0.460
H17.9 Corneal scar and opacity, unspecified	0.539	0.461
D04.3 Skin of other and unspecified parts of face	0.538	0.462
L53 Other erythematous conditions	0.537	0.462
D05.0 Lobular carcinoma in situ	0.536	0.464
C51 Malignant neoplasm of vulva	0.536	0.464
L71.8 Other rosacea	0.536	0.464
L71.1 Rhinophyma	0.536	0.464
L71.0 Perioral dermatitis	0.536	0.464
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.536	0.464
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.536	0.464
F52.7 Excessive sexual drive	0.536	0.464
F52.6 Nonorganic dyspareunia	0.536	0.464
F52.5 Nonorganic vaginismus	0.536	0.464
F52.4 Premature ejaculation	0.536	0.464
F52.3 Orgasmic dysfunction	0.536	0.464
F52.1 Sexual aversion and lack of sexual enjoyment	0.536	0.464
F52.0 Lack or loss of sexual desire	0.536	0.464
D03.7 Melanoma in situ of lower limb, including hip	0.536	0.464
H51 Other disorders of binocular movement	0.536	0.464
H33.4 Traction detachment of retina	0.535	0.465
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.535	0.465
M47.94 Spondylosis, unspecified (Thoracic region)	0.535	0.465
T36-T50 Poisoning by drugs, medicaments and biological substances	0.535	0.465
H18.7 Other corneal deformities	0.534	0.466
H18.3 Changes in corneal membranes	0.534	0.466
H18.0 Corneal pigmentations and deposits	0.534	0.466
H43-H45 Disorders of vitreous body and globe	0.534	0.466
L70.9 Acne, unspecified	0.534	0.466
L70.8 Other acne	0.534	0.466
L70.5 Acne excoriee des jeunes filles	0.534	0.466
L70.4 Infantile acne	0.534	0.466
L70.3 Acne tropica	0.534	0.466
L70.2 Acne varioliformis	0.534	0.466
L70.1 Acne conglobata	0.534	0.466
F89 Unspecified disorder of psychological development	0.534	0.466
F88 Other disorders of psychological development	0.534	0.466
F83 Mixed specific developmental disorders	0.534	0.466
F82 Specific developmental disorder of motor function	0.534	0.466
C55 Malignant neoplasm of uterus, part unspecified	0.533	0.467
C57 Malignant neoplasm of other and unspecified female genital organs	0.532	0.467
C58 Malignant neoplasm of placenta	0.532	0.467
C52 Malignant neoplasm of vagina	0.532	0.467
M63 Disorders of muscle in diseases classified elsewhere	0.531	0.469
M61 Calcification and ossification of muscle	0.531	0.469
M60 Myositis	0.531	0.469
M79.1 Myalgia	0.531	0.469
M92 Other juvenile osteochondrosis	0.530	0.470
M91 Juvenile osteochondrosis of hip and pelvis	0.530	0.470
M87.9 Osteonecrosis, unspecified	0.530	0.470
H18.8 Other specified disorders of cornea	0.529	0.471
D04.5 Skin of trunk	0.528	0.471
H47.0 Disorders of optic nerve, not elsewhere classified	0.528	0.471
M79.6 Pain in limb	0.528	0.472
F25 Schizoaffective disorders	0.527	0.473
M72 Fibroblastic disorders	0.527	0.473
M89.9 Disorder of bone, unspecified	0.527	0.473
C68 Malignant neoplasm of other and unspecified urinary organs	0.523	0.477
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.523	0.477
M54.15 Radiculopathy (Thoracolumbar region)	0.523	0.477
M54.14 Radiculopathy (Thoracic region)	0.523	0.477
M54.13 Radiculopathy (Cervicothoracic region)	0.523	0.477
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.523	0.477
M54.10 Radiculopathy (Multiple sites in spine)	0.523	0.477
C65 Malignant neoplasm of renal pelvis	0.523	0.477
M79.9 Soft tissue disorder, unspecified	0.521	0.479
H34.8 Other retinal vascular occlusions	0.521	0.479
F80 Specific developmental disorders of speech and language	0.521	0.479
H11.1 Conjunctival degenerations and deposits	0.519	0.481
M42 Spinal osteochondrosis	0.519	0.481
M40 Kyphosis and lordosis	0.519	0.481
H18.5 Hereditary corneal dystrophies	0.519	0.481
C90 Multiple myeloma and malignant plasma cell neoplasms	0.518	0.482
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.518	0.482
C67.5 Bladder neck	0.517	0.483
F33.8 Other recurrent depressive disorders	0.516	0.483
F33.4 Recurrent depressive disorder, currently in remission	0.516	0.483
F33.0 Recurrent depressive disorder, current episode mild	0.516	0.483
H16 Keratitis	0.516	0.484
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.515	0.485
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.515	0.485
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.515	0.485
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.515	0.485
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.515	0.485

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations