TreeWAS – Variant ID: rs231356

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
E11.3 With ophthalmic complications	0.998	0.002	0.000
E11.2 With renal complications	0.984	0.016	0.000
E11.4 With neurological complications	0.889	0.111	0.000
E11.0 With coma	0.868	0.132	0.000
E11.1 With ketoacidosis	0.851	0.149	0.000
E11.5 With peripheral circulatory complications	0.807	0.193	0.000
E11.6 With other specified complications	0.796	0.204	0.000
E11.7 With multiple complications	0.717	0.283	0.000
E10-E14 Diabetes mellitus	0.699	0.301	0.000
E11.8 With unspecified complications	0.658	0.342	0.000
E14 Unspecified diabetes mellitus	0.645	0.355	0.000
E14.3 With ophthalmic complications	0.637	0.363	0.000
E10 Insulin-dependent diabetes mellitus	0.505	0.495	0.000
E12 Malnutrition-related diabetes mellitus	0.501	0.498	0.000
E14.8 With unspecified complications	0.476	0.524	0.000
E14.7 With multiple complications	0.463	0.537	0.000
E14.0 With coma	0.463	0.537	0.000
E14.2 Withrenal complications	0.460	0.540	0.000
E14.5 With peripheral circulatory complications	0.436	0.564	0.000
E14.1 With ketoacidosis	0.427	0.573	0.000
E14.9 Without complications	0.423	0.577	0.000
E10.4 With neurological complications	0.420	0.580	0.000
E10.9 Without complications	0.408	0.592	0.000
C25 Malignant neoplasm of pancreas	0.405	0.595	0.000
C25.9 Pancreas, unspecified	0.402	0.598	0.000
C25.0 Head of pancreas	0.402	0.598	0.000
E10.3 With ophthalmic complications	0.397	0.603	0.000
E14.6 With other specified complications	0.391	0.609	0.000
E13 Other specified diabetes mellitus	0.388	0.612	0.000
C25.2 Tail of pancreas	0.380	0.620	0.000
E10.2 With renal complications	0.370	0.630	0.000
E10.6 With other specified complications	0.364	0.635	0.000
E10.7 With multiple complications	0.362	0.638	0.000
E12.9 Without complications	0.360	0.640	0.000
E12.8 With unspecified complications	0.360	0.640	0.000
E12.7 With multiple complications	0.360	0.640	0.000
E12.6 With other specified complications	0.360	0.640	0.000
E12.5 With peripheral circulatory complications	0.360	0.640	0.000
E12.4 With neurological complications	0.360	0.640	0.000
E12.3 With ophthalmic complications	0.360	0.640	0.000
E12.2 With renal complications	0.360	0.640	0.000
E12.1 With ketoacidosis	0.360	0.640	0.000
E12.0 With coma	0.360	0.640	0.000
E10.1 With ketoacidosis	0.351	0.649	0.000
C25.3 Pancreatic duct	0.348	0.652	0.000
E10.8 With unspecified complications	0.322	0.678	0.000
C25.1 Body of pancreas	0.317	0.683	0.000
E14.4 With neurological complications	0.311	0.689	0.001
E10.0 With coma	0.301	0.699	0.000
C25.4 Endocrine pancreas	0.290	0.710	0.000
C25.8 Overlapping lesion of pancreas	0.284	0.716	0.000
E13.8 With unspecified complications	0.278	0.721	0.000
E13.7 With multiple complications	0.278	0.721	0.000
E13.6 With other specified complications	0.278	0.721	0.000
E13.5 With peripheral circulatory complications	0.278	0.721	0.000
E13.4 With neurological complications	0.278	0.721	0.000
E13.3 With ophthalmic complications	0.278	0.721	0.000
E13.2 With renal complications	0.278	0.721	0.000
E13.1 With ketoacidosis	0.278	0.721	0.000
E13.0 With coma	0.278	0.721	0.000
C25.7 Other parts of pancreas	0.270	0.730	0.000
E10.5 With peripheral circulatory complications	0.260	0.740	0.000
H36.0 Diabetic retinopathy	0.228	0.772	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.191	0.809	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.186	0.814	0.000
E16.2 Hypoglycaemia, unspecified	0.183	0.817	0.000
E16 Other disorders of pancreatic internal secretion	0.182	0.818	0.000
E13.9 Without complications	0.165	0.835	0.000
E65-E68 Obesity and other hyperalimentation	0.158	0.842	0.000
E65 Localised adiposity	0.151	0.849	0.000
E70-E90 Metabolic disorders	0.136	0.864	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.135	0.865	0.000
E85 Amyloidosis	0.134	0.866	0.000
E15 Nondiabetic hypoglycaemic coma	0.133	0.867	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.131	0.869	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.131	0.869	0.000
E16.4 Abnormal secretion of gastrin	0.131	0.869	0.000
E16.3 Increased secretion of glucagon	0.131	0.869	0.000
E83.4 Disorders of magnesium metabolism	0.131	0.869	0.000
E83 Disorders of mineral metabolism	0.131	0.869	0.000
E85.9 Amyloidosis, unspecified	0.121	0.879	0.000
E83.3 Disorders of phosphorus metabolism	0.117	0.882	0.000
E85.4 Organ-limited amyloidosis	0.117	0.883	0.000
E67 Other hyperalimentation	0.113	0.886	0.000
E68 Sequelae of hyperalimentation	0.113	0.886	0.000
E85.3 Secondary systemic amyloidosis	0.113	0.887	0.000
E88 Other metabolic disorders	0.111	0.889	0.000
E85.8 Other amyloidosis	0.105	0.895	0.000
E16.1 Other hypoglycaemia	0.100	0.900	0.000
E40-E46 Malnutrition	0.099	0.900	0.000
E77 Disorders of glycoprotein metabolism	0.097	0.902	0.000
E76 Disorders of glycosaminoglycan metabolism	0.097	0.902	0.000
E72 Other disorders of amino-acid metabolism	0.097	0.902	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.097	0.902	0.000
E70 Disorders of aromatic amino-acid metabolism	0.097	0.902	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.097	0.902	0.000
H36 Retinal disorders in diseases classified elsewhere	0.096	0.904	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.096	0.904	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.096	0.904	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.096	0.904	0.000
E79 Disorders of purine and pyrimidine metabolism	0.096	0.904	0.000
E74 Other disorders of carbohydrate metabolism	0.095	0.905	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.094	0.906	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.094	0.906	0.000
E83.8 Other disorders of mineral metabolism	0.094	0.906	0.000
E83.2 Disorders of zinc metabolism	0.094	0.906	0.000
E83.0 Disorders of copper metabolism	0.094	0.906	0.000
E73 Lactose intolerance	0.093	0.907	0.000
E84 Cystic fibrosis	0.092	0.907	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.092	0.908	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.087	0.912	0.000
E88.3 Tumour lysis syndrome	0.085	0.915	0.000
E50-E64 Other nutritional deficiencies	0.083	0.917	0.000
E67.8 Other specified hyperalimentation	0.081	0.918	0.000
E67.3 Hypervitaminosis D	0.081	0.918	0.000
E67.2 Megavitamin-B6 syndrome	0.081	0.918	0.000
E67.1 Hypercarotenaemia	0.081	0.918	0.000
E67.0 Hypervitaminosis A	0.081	0.918	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.081	0.919	0.000
E88.9 Metabolic disorder, unspecified	0.080	0.920	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.080	0.920	0.000
E88.8 Other specified metabolic disorders	0.080	0.920	0.000
E00-E07 Disorders of thyroid gland	0.078	0.922	0.000
E88.2 Lipomatosis, not elsewhere classified	0.074	0.925	0.000
E74.0 Glycogen storage disease	0.074	0.926	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.071	0.928	0.000
E45 Retarded development following protein-energy malnutrition	0.071	0.928	0.000
E43 Unspecified severe protein-energy malnutrition	0.071	0.928	0.000
E42 Marasmic kwashiorkor	0.071	0.928	0.000
E41 Nutritional marasmus	0.071	0.928	0.000
E40 Kwashiorkor	0.071	0.928	0.000
E80.6 Other disorders of bilirubin metabolism	0.071	0.929	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.070	0.930	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.070	0.930	0.000
E70.3 Albinism	0.070	0.930	0.000
E70.2 Disorders of tyrosine metabolism	0.070	0.930	0.000
E70.1 Other hyperphenylalaninaemias	0.070	0.930	0.000
E70.0 Classical phenylketonuria	0.070	0.930	0.000
E71.3 Disorders of fatty-acid metabolism	0.070	0.930	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.070	0.930	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.070	0.930	0.000
E71.0 Maple-syrup-urine disease	0.070	0.930	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.070	0.930	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.070	0.930	0.000
E72.5 Disorders of glycine metabolism	0.070	0.930	0.000
E72.4 Disorders of ornithine metabolism	0.070	0.930	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.070	0.930	0.000
E72.2 Disorders of urea cycle metabolism	0.070	0.930	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.070	0.930	0.000
E72.0 Disorders of amino-acid transport	0.070	0.930	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.070	0.930	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.070	0.930	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.070	0.930	0.000
E76.2 Other mucopolysaccharidoses	0.070	0.930	0.000
E76.1 Mucopolysaccharidosis, type II	0.070	0.930	0.000
E76.0 Mucopolysaccharidosis, type I	0.070	0.930	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.070	0.930	0.000
E77.8 Other disorders of glycoprotein metabolism	0.070	0.930	0.000
E77.1 Defects in glycoprotein degradation	0.070	0.930	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.070	0.930	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.069	0.931	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.069	0.931	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.069	0.931	0.000
E79.1 Lesch-Nyhan syndrome	0.069	0.931	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.068	0.931	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.068	0.931	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.068	0.931	0.000
E74.2 Disorders of galactose metabolism	0.068	0.931	0.000
E74.1 Disorders of fructose metabolism	0.068	0.931	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.067	0.933	0.000
E80.2 Other porphyria	0.067	0.933	0.000
E73.8 Other lactose intolerance	0.067	0.933	0.000
E73.1 Secondary lactase deficiency	0.067	0.933	0.000
E73.0 Congenital lactase deficiency	0.067	0.933	0.000
E84.8 Cystic fibrosis with other manifestations	0.066	0.933	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.066	0.933	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.066	0.933	0.000
E83.1 Disorders of iron metabolism	0.067	0.933	0.000
E75.6 Lipid storage disorder, unspecified	0.066	0.934	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.066	0.934	0.000
E75.3 Sphingolipidosis, unspecified	0.066	0.934	0.000
E75.2 Other sphingolipidosis	0.066	0.934	0.000
E75.1 Other gangliosidosis	0.066	0.934	0.000
E75.0 GM2 gangliosidosis	0.066	0.934	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.066	0.934	0.000
E58 Dietary calcium deficiency	0.066	0.934	0.000
E54 Ascorbic acid deficiency	0.065	0.935	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.064	0.936	0.000
E80.1 Porphyria cutanea tarda	0.063	0.936	0.000
E80.5 Crigler-Najjar syndrome	0.063	0.937	0.000
E80.3 Defects of catalase and peroxydase	0.063	0.937	0.000
E80.0 Hereditary erythropoietic porphyria	0.063	0.937	0.000
E73.9 Lactose intolerance, unspecified	0.062	0.938	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.062	0.938	0.000
E84.9 Cystic fibrosis, unspecified	0.061	0.938	0.000
E75.5 Other lipid storage disorders	0.061	0.939	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.060	0.940	0.000
E63 Other nutritional deficiencies	0.060	0.940	0.000
E50 Vitamin A deficiency	0.060	0.940	0.000
E60 Dietary zinc deficiency	0.060	0.940	0.000
E59 Dietary selenium deficiency	0.060	0.940	0.000
E52 Niacin deficiency [pellagra]	0.060	0.940	0.000
E56 Other vitamin deficiencies	0.059	0.941	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.059	0.941	0.000
E89.2 Postprocedural hypoparathyroidism	0.059	0.941	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.058	0.941	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.058	0.941	0.000
E89.5 Postprocedural testicular hypofunction	0.058	0.941	0.000
E89.1 Postprocedural hypoinsulinaemia	0.058	0.941	0.000
E89.0 Postprocedural hypothyroidism	0.058	0.942	0.000
E06 Thyroiditis	0.057	0.942	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.056	0.943	0.000
E00 Congenital iodine-deficiency syndrome	0.056	0.943	0.000
E51 Thiamine deficiency	0.056	0.943	0.000
E07 Other disorders of thyroid	0.054	0.946	0.000
E44.1 Mild protein-energy malnutrition	0.051	0.948	0.000
E44.0 Moderate protein-energy malnutrition	0.051	0.948	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.049	0.951	0.000
E89.4 Postprocedural ovarian failure	0.048	0.952	0.000
E89.3 Postprocedural hypopituitarism	0.047	0.953	0.000
E55 Vitamin D deficiency	0.044	0.955	0.000
E06.1 Subacute thyroiditis	0.044	0.956	0.000
E53 Deficiency of other B group vitamins	0.044	0.956	0.000
E50.9 Vitamin A deficiency, unspecified	0.043	0.957	0.000
E50.8 Other manifestations of vitamin A deficiency	0.043	0.957	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.043	0.957	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.043	0.957	0.000
E50.5 Vitamin A deficiency with night blindness	0.043	0.957	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.043	0.957	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.043	0.957	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.043	0.957	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.043	0.957	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.043	0.957	0.000
E63.9 Nutritional deficiency, unspecified	0.043	0.957	0.000
E63.8 Other specified nutritional deficiencies	0.043	0.957	0.000
E63.1 Imbalance of constituents of food intake	0.043	0.957	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.043	0.957	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.043	0.957	0.000
E64.8 Sequelae of other nutritional deficiencies	0.043	0.957	0.000
E64.3 Sequelae of rickets	0.043	0.957	0.000
E64.2 Sequelae of vitamin C deficiency	0.043	0.957	0.000
E64.1 Sequelae of vitamin A deficiency	0.043	0.957	0.000
E64.0 Sequelae of protein-energy malnutrition	0.043	0.957	0.000
E56.9 Vitamin deficiency, unspecified	0.042	0.957	0.000
E56.8 Deficiency of other vitamins	0.042	0.957	0.000
E56.0 Deficiency of vitamin E	0.042	0.957	0.000
E06.3 Autoimmune thyroiditis	0.042	0.958	0.000
E56.1 Deficiency of vitamin K	0.042	0.958	0.000
E06.5 Other chronic thyroiditis	0.041	0.958	0.000
E06.4 Drug-induced thyroiditis	0.041	0.958	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.041	0.958	0.000
E06.0 Acute thyroiditis	0.041	0.958	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.041	0.959	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.041	0.959	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.041	0.959	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.041	0.959	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.041	0.959	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.041	0.959	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.041	0.959	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.041	0.959	0.000
E51.9 Thiamine deficiency, unspecified	0.041	0.959	0.000
E51.8 Other manifestations of thiamine deficiency	0.041	0.959	0.000
E51.1 Beriberi	0.041	0.959	0.000
E03 Other hypothyroidism	0.041	0.959	0.000
E05.8 Other thyrotoxicosis	0.040	0.960	0.000
E61 Deficiency of other nutrient elements	0.040	0.960	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.040	0.960	0.000
E06.9 Thyroiditis, unspecified	0.039	0.961	0.000
E07.1 Dyshormogenetic goitre	0.039	0.961	0.000
E07.0 Hypersecretion of calcitonin	0.039	0.961	0.000
E51.2 Wernicke's encephalopathy	0.037	0.962	0.000
E07.9 Disorder of thyroid, unspecified	0.037	0.963	0.000
E07.8 Other specified disorders of thyroid	0.037	0.963	0.000
E04 Other non-toxic goitre	0.036	0.964	0.000
E05.5 Thyroid crisis or storm	0.035	0.965	0.000
E05.4 Thyrotoxicosis factitia	0.035	0.965	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.035	0.965	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.035	0.965	0.000
E46 Unspecified protein-energy malnutrition	0.034	0.966	0.001
E53.9 Vitamin B deficiency, unspecified	0.034	0.966	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.033	0.967	0.000
E55.0 Rickets, active	0.032	0.968	0.000
E53.1 Pyridoxine deficiency	0.031	0.968	0.000
E53.0 Riboflavin deficiency	0.031	0.968	0.000
E03.8 Other specified hypothyroidism	0.030	0.970	0.000
E03.5 Myxoedema coma	0.029	0.971	0.000
E03.4 Atrophy of thyroid (acquired)	0.029	0.971	0.000
E03.3 Postinfectious hypothyroidism	0.029	0.971	0.000
E03.1 Congenital hypothyroidism without goitre	0.029	0.971	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.029	0.971	0.000
E61.9 Deficiency of nutrient element, unspecified	0.029	0.971	0.000
E61.8 Deficiency of other specified nutrient elements	0.029	0.971	0.000
E61.7 Deficiency of multiple nutrient elements	0.029	0.971	0.000
E61.6 Vanadium deficiency	0.029	0.971	0.000
E61.5 Molybdenum deficiency	0.029	0.971	0.000
E61.4 Chromium deficiency	0.029	0.971	0.000
E61.3 Manganese deficiency	0.029	0.971	0.000
E61.0 Copper deficiency	0.029	0.971	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.028	0.972	0.000
E61.2 Magnesium deficiency	0.026	0.974	0.000
E04.1 Non-toxic single thyroid nodule	0.026	0.974	0.000
E04.0 Non-toxic diffuse goitre	0.026	0.974	0.000
E04.8 Other specified non-toxic goitre	0.026	0.974	0.000
D86.9 Sarcoidosis, unspecified	0.024	0.976	0.000
E04.2 Non-toxic multinodular goitre	0.024	0.976	0.000
E66 Obesity	0.023	0.977	0.000
D86 Sarcoidosis	0.020	0.980	0.000
C15-C26 Malignant neoplasms of digestive organs	0.019	0.981	0.000
D86.0 Sarcoidosis of lung	0.019	0.981	0.000
C15 Malignant neoplasm of oesophagus	0.019	0.981	0.000
E83.5 Disorders of calcium metabolism	0.019	0.981	0.000
E66.0 Obesity due to excess calories	0.019	0.981	0.000
C15.4 Middle third of oesophagus	0.017	0.983	0.000
E66.1 Drug-induced obesity	0.017	0.983	0.000
C15.9 Oesophagus, unspecified	0.017	0.983	0.000
E55.9 Vitamin D deficiency, unspecified	0.017	0.983	0.000
E80.4 Gilbert's syndrome	0.016	0.983	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.016	0.984	0.000
D86.1 Sarcoidosis of lymph nodes	0.016	0.984	0.000
E05.9 Thyrotoxicosis, unspecified	0.016	0.984	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.016	0.984	0.000
C15.1 Thoracic part of oesophagus	0.016	0.984	0.000
C15.0 Cervical part of oesophagus	0.016	0.984	0.000
E86 Volume depletion	0.015	0.985	0.000
C21 Malignant neoplasm of anus and anal canal	0.015	0.985	0.000
E61.1 Iron deficiency	0.015	0.985	0.000
D86.8 Sarcoidosis of other and combined sites	0.015	0.985	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.015	0.985	0.000
C15.3 Upper third of oesophagus	0.014	0.986	0.000
C26.0 Intestinal tract, part unspecified	0.014	0.986	0.000
C15.8 Overlapping lesion of oesophagus	0.014	0.986	0.000
C15.2 Abdominal part of oesophagus	0.014	0.986	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.014	0.986	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.014	0.986	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.986	0.014
C17 Malignant neoplasm of small intestine	0.013	0.987	0.000
C24.9 Biliary tract, unspecified	0.013	0.987	0.000
C24.0 Extrahepatic bile duct	0.013	0.987	0.000
D86.3 Sarcoidosis of skin	0.012	0.988	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.012	0.988	0.000
C15.5 Lower third of oesophagus	0.012	0.988	0.000
C21.0 Anus, unspecified	0.012	0.988	0.000
C22.1 Intrahepatic bile duct carcinoma	0.012	0.988	0.000
C17.2 Ileum	0.012	0.988	0.000
C26.8 Overlapping lesion of digestive system	0.012	0.988	0.000
C26.1 Spleen	0.012	0.988	0.000
T83.2 Mechanical complication of graft of urinary organ	0.012	0.988	0.000
C24.8 Overlapping lesion of biliary tract	0.012	0.988	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.011	0.988	0.000
C22.9 Liver, unspecified	0.012	0.988	0.000
C26.9 Ill-defined sites within the digestive system	0.011	0.989	0.000
C21.1 Anal canal	0.011	0.989	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.011	0.989	0.000
C21.2 Cloacogenic zone	0.011	0.989	0.000
C22.7 Other specified carcinomas of liver	0.011	0.989	0.000
C22.4 Other sarcomas of liver	0.011	0.989	0.000
C22.3 Angiosarcoma of liver	0.011	0.989	0.000
C22.2 Hepatoblastoma	0.011	0.989	0.000
C45.0 Mesothelioma of pleura	0.000	0.989	0.011
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.011	0.989	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.010	0.989	0.000
C17.1 Jejunum	0.010	0.990	0.000
C24.1 Ampulla of Vater	0.010	0.990	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.010	0.990	0.000
C17.8 Overlapping lesion of small intestine	0.010	0.990	0.000
C17.3 Meckel's diverticulum	0.010	0.990	0.000
I27.0 Primary pulmonary hypertension	0.010	0.990	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.010	0.990	0.000
I27 Other pulmonary heart diseases	0.010	0.990	0.000
I27.9 Pulmonary heart disease, unspecified	0.009	0.991	0.000
I27.2 Other secondary pulmonary hypertension	0.009	0.991	0.000
E53.8 Deficiency of other specified B group vitamins	0.009	0.991	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.009	0.991	0.000
C23 Malignant neoplasm of gallbladder	0.008	0.991	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.008	0.991	0.000
R87.6 Abnormal cytological findings	0.008	0.992	0.000
C45 Mesothelioma	0.000	0.992	0.008
C17.0 Duodenum	0.008	0.992	0.000
C45.9 Mesothelioma, unspecified	0.000	0.992	0.008
C22.0 Liver cell carcinoma	0.008	0.992	0.000
I27.8 Other specified pulmonary heart diseases	0.007	0.993	0.000
N18.9 Chronic renal failure, unspecified	0.007	0.993	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.007	0.993	0.000
Z89.5 Acquired absence of leg at or below knee	0.007	0.993	0.000
I27.1 Kyphoscoliotic heart disease	0.007	0.993	0.000
D80-D89 Certain disorders involving the immune mechanism	0.007	0.993	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.993	0.007
C45.7 Mesothelioma of other sites	0.000	0.993	0.007
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.993	0.007
C17.9 Small intestine, unspecified	0.006	0.993	0.000
C45.2 Mesothelioma of pericardium	0.000	0.994	0.006
C45.1 Mesothelioma of peritoneum	0.000	0.994	0.006
Z89 Acquired absence of limb	0.006	0.994	0.000
R87 Abnormal findings in specimens from female genital organs	0.006	0.994	0.000
E04.9 Non-toxic goitre, unspecified	0.006	0.994	0.000
D80 Immunodeficiency with predominantly antibody defects	0.006	0.994	0.000
R87.9 Unspecified abnormal finding	0.006	0.994	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.006	0.994	0.000
Z89.9 Acquired absence of limb, unspecified	0.006	0.994	0.000
Z89.4 Acquired absence of foot and ankle	0.005	0.994	0.000
I78.1 Naevus, nonneoplastic	0.000	0.995	0.005
T86.0 Bone-marrow transplant rejection	0.005	0.995	0.000
E20-E35 Disorders of other endocrine glands	0.005	0.995	0.000
D82 Immunodeficiency associated with other major defects	0.005	0.995	0.000
D81 Combined immunodeficiencies	0.005	0.995	0.000
R87.7 Abnormal histological findings	0.005	0.995	0.000
R06.8 Other and unspecified abnormalities of breathing	0.000	0.995	0.005
D84 Other immunodeficiencies	0.005	0.995	0.000
I42.0 Dilated cardiomyopathy	0.005	0.995	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.005	0.995	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.005	0.995	0.000
F20.9 Schizophrenia, unspecified	0.000	0.995	0.005
I78 Diseases of capillaries	0.000	0.995	0.005
Z89.2 Acquired absence of upper limb above wrist	0.005	0.995	0.000
L89.1 Stage II decubitus ulcer	0.005	0.995	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.005	0.995	0.000
D84.1 Defects in the complement system	0.005	0.995	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.005	0.995	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.005	0.995	0.000
Z89.1 Acquired absence of hand and wrist	0.005	0.995	0.000
R87.8 Other abnormal findings	0.005	0.995	0.000
R87.5 Abnormal microbiological findings	0.005	0.995	0.000
R87.4 Abnormal immunological findings	0.005	0.995	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.005	0.995	0.000
R87.1 Abnormal level of hormones	0.005	0.995	0.000
R87.0 Abnormal level of enzymes	0.005	0.995	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
D83 Common variable immunodeficiency	0.005	0.995	0.000
C18.7 Sigmoid colon	0.000	0.995	0.005
L89.2 Stage III decubitus ulcer	0.005	0.995	0.000
H20.9 Iridocyclitis, unspecified	0.005	0.995	0.000
L89 Decubitus ulcer	0.005	0.995	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.004	0.995	0.000
E31 Polyglandular dysfunction	0.004	0.995	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.995	0.004
E25 Adrenogenital disorders	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.004	0.996	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.004	0.996	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.004	0.996	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.004	0.996	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.004	0.996	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.004	0.996	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.004	0.996	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.004	0.996	0.000
E26 Hyperaldosteronism	0.004	0.996	0.000
N18 Chronic renal failure	0.004	0.996	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
E30 Disorders of puberty, not elsewhere classified	0.004	0.996	0.000
N18.4 Chronic kidney disease, stage 4	0.004	0.996	0.000
D81.9 Combined immunodeficiency, unspecified	0.004	0.996	0.000
D81.8 Other combined immunodeficiencies	0.004	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.004	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.004	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.004	0.996	0.000
D81.4 Nezelof's syndrome	0.004	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.004	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.004	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.004	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.004	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.004	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.004	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.004	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.004	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.004	0.996	0.000
D82.1 Di George's syndrome	0.004	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.004	0.996	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.004	0.996	0.000
T79.6 Traumatic ischaemia of muscle	0.004	0.996	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.996	0.004
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.004	0.996	0.000
Z89.6 Acquired absence of leg above knee	0.004	0.996	0.000
A63.0 Anogenital (venereal) warts	0.004	0.996	0.000
N18.3 Chronic kidney disease, stage 3	0.004	0.996	0.000
D84.8 Other specified immunodeficiencies	0.004	0.996	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.996	0.004
I78.9 Disease of capillaries, unspecified	0.000	0.996	0.004
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.996	0.004
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.004	0.996	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.996	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.996	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.996	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.003	0.996	0.000
E29 Testicular dysfunction	0.003	0.996	0.000
F20 Schizophrenia	0.000	0.996	0.004
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.996	0.000
N18.1 Chronic kidney disease, stage 1	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations