TreeWAS – Variant ID: rs2323266

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.571	0.429	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.569	0.431	0.000
T42.4 Benzodiazepines	0.545	0.455	0.000
T42.0 Hydantoin derivatives	0.510	0.490	0.000
T42.1 Iminostilbenes	0.475	0.525	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.462	0.538	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.408	0.592	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.408	0.592	0.000
T42.3 Barbiturates	0.408	0.592	0.000
T42.2 Succinimides and oxazolidinediones	0.408	0.592	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.396	0.604	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.380	0.620	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.366	0.634	0.000
T40.2 Other opioids	0.356	0.644	0.000
T40.4 Other synthetic narcotics	0.327	0.673	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.324	0.675	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.318	0.682	0.000
T50.1 Loop [high-ceiling] diuretics	0.300	0.700	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.289	0.711	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.284	0.716	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.284	0.716	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.284	0.716	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.278	0.722	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.273	0.727	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.272	0.728	0.000
T40.8 Lysergide [LSD]	0.272	0.728	0.000
T40.7 Cannabis (derivatives)	0.272	0.728	0.000
T40.5 Cocaine	0.272	0.728	0.000
T40.3 Methadone	0.272	0.728	0.000
T40.1 Heroin	0.272	0.728	0.000
T40.0 Opium	0.272	0.728	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.272	0.728	0.000
T50.8 Diagnostic agents	0.271	0.729	0.000
T36 Poisoning by systemic antibiotics	0.269	0.731	0.000
T40.6 Other and unspecified narcotics	0.269	0.731	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.266	0.733	0.000
T50.7 Analeptics and opioid receptor antagonists	0.262	0.737	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.262	0.737	0.000
T50.5 Appetite depressants	0.262	0.737	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.262	0.737	0.000
T50.0 Mineralocorticoids and their antagonists	0.262	0.737	0.000
T50.4 Drugs affecting uric acid metabolism	0.260	0.740	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.242	0.758	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.240	0.760	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.233	0.767	0.000
T37.5 Antiviral drugs	0.233	0.767	0.000
T37.4 Anthelminthics	0.233	0.767	0.000
T37.3 Other antiprotozoal drugs	0.233	0.767	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.233	0.767	0.000
T37.1 Antimycobacterial drugs	0.233	0.767	0.000
T37.0 Sulphonamides	0.233	0.767	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.221	0.779	0.000
T46.1 Calcium-channel blockers	0.212	0.787	0.000
T43.6 Psychostimulants with abuse potential	0.211	0.789	0.000
T41.5 Therapeutic gases	0.204	0.796	0.000
T41.4 Anaesthetic, unspecified	0.204	0.796	0.000
T41.3 Local anaesthetics	0.204	0.796	0.000
T41.2 Other and unspecified general anaesthetics	0.204	0.796	0.000
T41.1 Intravenous anaesthetics	0.204	0.796	0.000
T41.0 Inhaled anaesthetics	0.204	0.796	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.204	0.796	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.204	0.796	0.000
T48.5 Anti-common-cold drugs	0.204	0.796	0.000
T48.4 Expectorants	0.204	0.796	0.000
T48.3 Antitussives	0.204	0.796	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.204	0.796	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.204	0.796	0.000
T48.0 Oxytocic drugs	0.204	0.796	0.000
T49.9 Topical agent, unspecified	0.204	0.796	0.000
T49.8 Other topical agents	0.204	0.796	0.000
T49.7 Dental drugs, topically applied	0.204	0.796	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.204	0.796	0.000
T49.5 Ophthalmological drugs and preparations	0.204	0.796	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.204	0.796	0.000
T49.3 Emollients, demulcents and protectants	0.204	0.796	0.000
T49.2 Local astringents and local detergents	0.204	0.796	0.000
T49.1 Antipruritics	0.204	0.796	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.204	0.796	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.202	0.798	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.199	0.801	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.199	0.801	0.000
T46.7 Peripheral vasodilators	0.199	0.801	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.199	0.801	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.199	0.801	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.195	0.805	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.195	0.805	0.000
T47.7 Emetics	0.195	0.805	0.000
T47.6 Antidiarrhoeal drugs	0.195	0.805	0.000
T47.5 Digestants	0.195	0.805	0.000
T47.4 Other laxatives	0.195	0.805	0.000
T47.3 Saline and osmotic laxatives	0.195	0.805	0.000
T47.2 Stimulant laxatives	0.195	0.805	0.000
T47.0 Histamine H(2)-receptor antagonists	0.195	0.805	0.000
T36.9 Systemic antibiotic, unspecified	0.193	0.807	0.000
T36.8 Other systemic antibiotics	0.193	0.807	0.000
T36.7 Antifungal antibiotics, systemically used	0.193	0.807	0.000
T36.6 Rifamycins	0.193	0.807	0.000
T36.5 Aminoglycosides	0.193	0.807	0.000
T36.4 Tetracyclines	0.193	0.807	0.000
T36.3 Macrolides	0.193	0.807	0.000
T36.2 Chloramphenicol group	0.193	0.807	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.193	0.807	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.192	0.808	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.191	0.809	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.191	0.809	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.191	0.809	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.191	0.809	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.191	0.809	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.191	0.809	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.191	0.809	0.000
T44.0 Anticholinesterase agents	0.191	0.809	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.186	0.814	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.185	0.815	0.000
T43.2 Other and unspecified antidepressants	0.185	0.815	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.183	0.817	0.000
T38.1 Thyroid hormones and substitutes	0.181	0.819	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.181	0.819	0.000
T36.0 Penicillins	0.178	0.821	0.000
T38.9 Other and unspecified hormone antagonists	0.173	0.826	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.173	0.826	0.000
T38.7 Androgens and anabolic congeners	0.173	0.826	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.173	0.826	0.000
T38.5 Other oestrogens and progestogens	0.173	0.826	0.000
T38.4 Oral contraceptives	0.173	0.826	0.000
T38.2 Antithyroid drugs	0.173	0.826	0.000
T38.0 Glucocorticoids and synthetic analogues	0.173	0.826	0.000
T43.9 Psychotropic drug, unspecified	0.172	0.828	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.172	0.828	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.172	0.828	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.161	0.839	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.159	0.841	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.155	0.844	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.152	0.848	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.145	0.855	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.144	0.856	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.136	0.864	0.000
T39.4 Antirheumatics, not elsewhere classified	0.133	0.866	0.000
T39.2 Pyrazolone derivatives	0.133	0.866	0.000
T39.1 4-Aminophenol derivatives	0.124	0.876	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.117	0.882	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.115	0.885	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.109	0.891	0.000
T45.8 Other primarily systemic and haematological agents	0.109	0.891	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.109	0.891	0.000
T45.6 Fibrinolysis-affecting drugs	0.109	0.891	0.000
T45.4 Iron and its compounds	0.109	0.891	0.000
T45.3 Enzymes, not elsewhere classified	0.109	0.891	0.000
T45.2 Vitamins, not elsewhere classified	0.100	0.899	0.000
T45.0 Antiallergic and antiemetic drugs	0.092	0.907	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.090	0.909	0.001
T45.5 Anticoagulants	0.078	0.921	0.001
T39.0 Salicylates	0.060	0.939	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.053	0.947	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.000	0.962	0.038
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.980	0.020
H61.0 Perichondritis of external ear	0.000	0.984	0.016
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.984	0.016
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.986	0.014
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.987	0.013
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.988	0.012
H61.2 Impacted cerumen	0.000	0.988	0.012
N97.1 Female infertility of tubal origin	0.012	0.988	0.000
H61 Other disorders of external ear	0.000	0.988	0.012
H61.3 Acquired stenosis of external ear canal	0.000	0.990	0.010
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.990	0.010
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.990	0.010
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.990	0.010
H57.1 Ocular pain	0.009	0.991	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.991	0.009
N60.8 Other benign mammary dysplasias	0.000	0.991	0.009
C71 Malignant neoplasm of brain	0.000	0.991	0.009
C71.9 Brain, unspecified	0.000	0.991	0.009
S62.3 Fracture of other metacarpal bone	0.000	0.992	0.008
C71.8 Overlapping lesion of brain	0.000	0.992	0.008
C71.1 Frontal lobe	0.000	0.992	0.008
N60 Benign mammary dysplasia	0.000	0.992	0.008
C71.4 Occipital lobe	0.000	0.992	0.008
H61.1 Non-infective disorders of pinna	0.000	0.992	0.007
N60.3 Fibrosclerosis of breast	0.000	0.992	0.008
H57 Other disorders of eye and adnexa	0.008	0.992	0.000
H57.8 Other specified disorders of eye and adnexa	0.007	0.993	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.993	0.007
C71.0 Cerebrum, except lobes and ventricles	0.000	0.993	0.007
H61.9 Disorder of external ear, unspecified	0.000	0.993	0.007
H61.8 Other specified disorders of external ear	0.000	0.993	0.007
C71.3 Parietal lobe	0.000	0.993	0.007
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.993	0.007
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.993	0.007
N60.4 Mammary duct ectasia	0.000	0.993	0.007
N97 Female infertility	0.007	0.993	0.000
C71.7 Brain stem	0.000	0.993	0.006
C71.5 Cerebral ventricle	0.000	0.993	0.006
N97.8 Female infertility of other origin	0.006	0.994	0.000
C71.2 Temporal lobe	0.000	0.994	0.006
C71.6 Cerebellum	0.000	0.994	0.006
S62.31 Fracture of other metacarpal bone (open)	0.000	0.994	0.006
N60.0 Solitary cyst of breast	0.000	0.994	0.006
H57.0 Anomalies of pupillary function	0.005	0.994	0.000
N97.4 Female infertility associated with male factors	0.005	0.995	0.000
N97.3 Female infertility of cervical origin	0.005	0.995	0.000
N97.2 Female infertility of uterine origin	0.005	0.995	0.000
N97.0 Female infertility associated with anovulation	0.005	0.995	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.005	0.995	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.995	0.005
H57.9 Disorder of eye and adnexa, unspecified	0.005	0.995	0.000
N60.2 Fibroadenosis of breast	0.000	0.995	0.005
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.005	0.995	0.000
S05.1 Contusion of eyeball and orbital tissues	0.005	0.995	0.000
H55-H59 Other disorders of eye and adnexa	0.005	0.995	0.000
N97.9 Female infertility, unspecified	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
Y83.4 Other reconstructive surgery	0.000	0.996	0.004
Q61.0 Congenital single renal cyst	0.004	0.996	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.004	0.996	0.000
I95.1 Orthostatic hypotension	0.004	0.996	0.000
H59.0 Vitreous syndrome following cataract surgery	0.004	0.996	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.004	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.004	0.996	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.004	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
C92.0 Acute myeloid leukaemia	0.004	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.996	0.000
K46 Unspecified abdominal hernia	0.000	0.996	0.004
C91.1 Chronic lymphocytic leukaemia	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q61.4 Renal dysplasia	0.003	0.996	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
H60-H62 Diseases of external ear	0.000	0.997	0.003
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.997	0.003
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.003	0.997	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.003	0.997	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.000	0.997	0.003
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
Q85.1 Tuberous sclerosis	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
C91 Lymphoid leukaemia	0.003	0.997	0.000
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.003	0.997	0.000
I42.9 Cardiomyopathy, unspecified	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
S13.4 Sprain and strain of cervical spine	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
H01.0 Blepharitis	0.000	0.997	0.003
C92 Myeloid leukaemia	0.003	0.997	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.003	0.997	0.000
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.997	0.003
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.003	0.997	0.000
C91.9 Lymphoid leukaemia, unspecified	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.997	0.003
M10.97 Gout, unspecified (Ankle and foot)	0.003	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
C90.0 Multiple myeloma	0.003	0.997	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.997	0.000
C70 Malignant neoplasm of meninges	0.000	0.997	0.003
C91.4 Hairy-cell leukaemia	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.997	0.000
Q38.2 Macroglossia	0.002	0.997	0.000
Q38.1 Ankyloglossia	0.002	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.997	0.000
C91.5 Adult T-cell leukaemia	0.003	0.997	0.000
D05.0 Lobular carcinoma in situ	0.000	0.997	0.003
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.997	0.000
Q45.1 Annular pancreas	0.002	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.997	0.003
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.997	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.003	0.997	0.000
C92.9 Myeloid leukaemia, unspecified	0.002	0.997	0.000
Q43.7 Persistent cloaca	0.002	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.997	0.000
Q43.5 Ectopic anus	0.002	0.997	0.000
Q43.4 Duplication of intestine	0.002	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.997	0.000
Q43.1 Hirschsprung's disease	0.002	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.997	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.002	0.997	0.000
C69.3 Choroid	0.000	0.997	0.002
C91.8 Mature B-cell leukaemia Burkitt-type	0.002	0.997	0.000
C91.7 Other lymphoid leukaemia	0.002	0.997	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.002	0.997	0.000
C91.3 Prolymphocytic leukaemia	0.002	0.997	0.000
C91.2 Subacute lymphocytic leukaemia	0.002	0.997	0.000
C92.7 Other myeloid leukaemia	0.002	0.997	0.000
F20.9 Schizophrenia, unspecified	0.000	0.997	0.003
F20.0 Paranoid schizophrenia	0.000	0.997	0.002
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.997	0.002
Q63 Other congenital malformations of kidney	0.002	0.997	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.998	0.002
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
N61 Inflammatory disorders of breast	0.000	0.998	0.002
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
K50.8 Other Crohn's disease	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.002	0.998	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.002	0.998	0.000
C92.5 Acute myelomonocytic leukaemia	0.002	0.998	0.000
C92.3 Myeloid sarcoma	0.002	0.998	0.000
C92.2 Subacute myeloid leukaemia	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.002
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
C91.0 Acute lymphoblastic leukaemia	0.002	0.998	0.000
C92.4 Acute promyelocytic leukaemia	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.998	0.002
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.998	0.002
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
H62.2 Otitis externa in mycoses	0.000	0.998	0.002
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.998	0.002
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.998	0.002
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.000	0.998	0.002
C70.9 Meninges, unspecified	0.000	0.998	0.002
C70.1 Spinal meninges	0.000	0.998	0.002
C70.0 Cerebral meninges	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
C86 Other specified types of T/NK-cell lymphoma	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
N60-N64 Disorders of breast	0.000	0.998	0.002
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.998	0.002
C69.6 Orbit	0.000	0.998	0.002
C69.5 Lachrymal gland and duct	0.000	0.998	0.002
C69.4 Ciliary body	0.000	0.998	0.002
C69.1 Cornea	0.000	0.998	0.002
C69.0 Conjunctiva	0.000	0.998	0.002
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
R09.1 Pleurisy	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
N62 Hypertrophy of breast	0.000	0.998	0.002
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.002	0.998	0.000
C83.5 Lymphoblastic (diffuse)	0.002	0.998	0.000
C83.4 Immunoblastic (diffuse)	0.002	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.000	0.998	0.002
C72.9 Central nervous system, unspecified	0.000	0.998	0.002
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.998	0.002
C72.5 Other and unspecified cranial nerves	0.000	0.998	0.002
C72.4 Acoustic nerve	0.000	0.998	0.002
C72.3 Optic nerve	0.000	0.998	0.002
C72.2 Olfactory nerve	0.000	0.998	0.002
C72.1 Cauda equina	0.000	0.998	0.002
C86.5 Angioimmunoblastic T-cell lymphoma	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.998	0.002
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
C95 Leukaemia of unspecified cell type	0.002	0.998	0.000
C93 Monocytic leukaemia	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.002	0.998	0.000
Q80.8 Other congenital ichthyosis	0.002	0.998	0.000
Q80.4 Harlequin foetus	0.002	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.998	0.000
Q80.2 Lamellar ichthyosis	0.002	0.998	0.000
Q80.1 X-linked ichthyosis	0.002	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.998	0.000
Q84.6 Other congenital malformations of nails	0.002	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.998	0.000
Q84.4 Congenital leukonychia	0.002	0.998	0.000
Q84.3 Anonychia	0.002	0.998	0.000
Q84.2 Other congenital malformations of hair	0.002	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.002	0.998	0.000
Q84.0 Congenital alopecia	0.002	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.002	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.002	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.002	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.002	0.998	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
C94 Other leukaemias of specified cell type	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
C69.2 Retina	0.000	0.998	0.002
Q82.9 Congenital malformation of skin, unspecified	0.002	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.002	0.998	0.000
Q82.3 Incontinentia pigmenti	0.002	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
Q90.9 Down's syndrome, unspecified	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q82.2 Mastocytosis	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
X69.9 Unspecified place	0.002	0.998	0.000
F20 Schizophrenia	0.000	0.998	0.002
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
Z91.5 Personal history of self-harm	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations