TreeWAS – Variant ID: rs236670

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.993	0.007
Chapter II Neoplasms	0.991	0.009
Chapter IV Endocrine, nutritional and metabolic diseases	0.981	0.019
D00-D09 In situ neoplasms	0.979	0.021
Chapter XII Diseases of the skin and subcutaneous tissue	0.973	0.027
Chapter VII Diseases of the eye and adnexa	0.972	0.028
L40-L45 Papulosquamous disorders	0.966	0.034
L40 Psoriasis	0.955	0.045
L40.9 Psoriasis, unspecified	0.951	0.049
D05 Carcinoma in situ of breast	0.950	0.050
E70-E90 Metabolic disorders	0.948	0.052
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.941	0.059
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.924	0.076
M45-M49 Spondylopathies	0.902	0.098
M20-M25 Other joint disorders	0.897	0.103
E00-E07 Disorders of thyroid gland	0.893	0.107
C43-C44 Melanoma and other malignant neoplasms of skin	0.885	0.115
M47 Spondylosis	0.882	0.118
C15-C26 Malignant neoplasms of digestive organs	0.879	0.121
D37-D48 Neoplasms of uncertain or unknown behaviour	0.876	0.124
D05.9 Carcinoma in situ of breast, unspecified	0.873	0.127
M20 Acquired deformities of fingers and toes	0.867	0.133
E86 Volume depletion	0.865	0.135
D05.1 Intraductal carcinoma in situ	0.863	0.137
D10-D36 Benign neoplasms	0.862	0.138
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.854	0.146
E07 Other disorders of thyroid	0.854	0.146
H02 Other disorders of eyelid	0.853	0.147
L60-L75 Disorders of skin appendages	0.850	0.150
E83 Disorders of mineral metabolism	0.848	0.152
H30-H36 Disorders of choroid and retina	0.847	0.153
H55-H59 Other disorders of eye and adnexa	0.840	0.160
L43 Lichen planus	0.833	0.167
Chapter V Mental and behavioural disorders	0.829	0.171
E07.9 Disorder of thyroid, unspecified	0.826	0.174
M47.8 Other spondylosis	0.823	0.177
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.822	0.178
C18 Malignant neoplasm of colon	0.816	0.184
D04 Carcinoma in situ of skin	0.812	0.188
Chapter IX Diseases of the circulatory system	0.811	0.189
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.811	0.189
M47.9 Spondylosis, unspecified	0.809	0.191
M25 Other joint disorders, not elsewhere classified	0.806	0.194
Chapter VIII Diseases of the ear and mastoid process	0.799	0.201
D06 Carcinoma in situ of cervix uteri	0.797	0.203
Chapter XXII Codes for special purposes	0.790	0.210
I70-I79 Diseases of arteries, arterioles and capillaries	0.789	0.211
M20.3 Other deformity of hallux (acquired)	0.789	0.211
C44 Other malignant neoplasms of skin	0.783	0.217
M47.82 Other spondylosis (Cervical region)	0.780	0.220
D03 Melanoma in situ	0.778	0.222
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.778	0.222
M86-M90 Other osteopathies	0.777	0.223
L50-L54 Urticaria and erythema	0.773	0.227
E50-E64 Other nutritional deficiencies	0.767	0.233
H01 Other inflammation of eyelid	0.766	0.234
Chapter XX External causes of morbidity and mortality	0.759	0.241
E73 Lactose intolerance	0.758	0.241
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.757	0.243
M65-M68 Disorders of synovium and tendon	0.757	0.243
E83.1 Disorders of iron metabolism	0.757	0.243
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.751	0.249
E80 Disorders of porphyrin and bilirubin metabolism	0.750	0.250
D18 Haemangioma and lymphangioma, any site	0.748	0.252
H53-H54 Visual disturbances and blindness	0.746	0.254
D25 Leiomyoma of uterus	0.746	0.254
E04 Other non-toxic goitre	0.743	0.257
L72 Follicular cysts of skin and subcutaneous tissue	0.741	0.259
H02.8 Other specified disorders of eyelid	0.740	0.260
D17 Benign lipomatous neoplasm	0.739	0.261
H04 Disorders of lachrymal system	0.739	0.261
L43.9 Lichen planus, unspecified	0.738	0.262
Chapter VI Diseases of the nervous system	0.735	0.265
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.734	0.266
H35 Other retinal disorders	0.734	0.266
F00-F09 Organic, including symptomatic, mental disorders	0.733	0.267
M20.0 Deformity of finger(s)	0.733	0.267
M25.5 Pain in joint	0.731	0.269
C44.1 Skin of eyelid, including canthus	0.731	0.269
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.731	0.269
M20.1 Hallux valgus (acquired)	0.731	0.269
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.729	0.271
E87 Other disorders of fluid, electrolyte and acid-base balance	0.727	0.272
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.727	0.273
D05.0 Lobular carcinoma in situ	0.726	0.274
E10-E14 Diabetes mellitus	0.725	0.275
M20.5 Other deformities of toe(s) (acquired)	0.724	0.276
D33 Benign neoplasm of brain and other parts of central nervous system	0.722	0.278
D32 Benign neoplasm of meninges	0.721	0.279
M22 Disorders of patella	0.719	0.281
M47.99 Spondylosis, unspecified (Site unspecified)	0.718	0.282
H02.9 Disorder of eyelid, unspecified	0.715	0.285
C18.9 Colon, unspecified	0.714	0.286
E83.4 Disorders of magnesium metabolism	0.713	0.287
H02.3 Blepharochalasis	0.713	0.287
Chapter XVI Certain conditions originating in the perinatal period	0.712	0.288
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.711	0.289
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.711	0.289
C40-C41 Malignant neoplasms of bone and articular cartilage	0.711	0.289
H57 Other disorders of eye and adnexa	0.709	0.291
I30-I52 Other forms of heart disease	0.709	0.291
F30-F39 Mood [affective] disorders	0.708	0.292
C81 Hodgkin's disease	0.706	0.294
H25-H28 Disorders of lens	0.704	0.296
E40-E46 Malnutrition	0.703	0.297
D09 Carcinoma in situ of other and unspecified sites	0.702	0.298
D02 Carcinoma in situ of middle ear and respiratory system	0.702	0.298
D01 Carcinoma in situ of other and unspecified digestive organs	0.702	0.298
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.702	0.298
C34 Malignant neoplasm of bronchus and lung	0.700	0.300
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.698	0.302
L10-L14 Bullous disorders	0.698	0.302
C19 Malignant neoplasm of rectosigmoid junction	0.697	0.303
H46-H48 Disorders of optic nerve and visual pathways	0.697	0.303
C43 Malignant melanoma of skin	0.697	0.303
L20-L30 Dermatitis and eczema	0.697	0.303
H10-H13 Disorders of conjunctiva	0.696	0.303
C51-C58 Malignant neoplasms of female genital organs	0.694	0.306
C83 Diffuse non-Hodgkin's lymphoma	0.694	0.306
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.693	0.307
L44 Other papulosquamous disorders	0.692	0.308
L41 Parapsoriasis	0.692	0.308
L45 Papulosquamous disorders in diseases classified elsewhere	0.692	0.308
L42 Pityriasis rosea	0.692	0.308
E20-E35 Disorders of other endocrine glands	0.689	0.311
I77 Other disorders of arteries and arterioles	0.689	0.311
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.688	0.312
D07 Carcinoma in situ of other and unspecified genital organs	0.686	0.314
M20.6 Acquired deformity of toe(s), unspecified	0.685	0.315
L40.8 Other psoriasis	0.684	0.315
L40.4 Guttate psoriasis	0.684	0.315
L40.3 Pustulosis palmaris et plantaris	0.684	0.315
L40.2 Acrodermatitis continua	0.684	0.315
L40.1 Generalised pustular psoriasis	0.684	0.315
L40.0 Psoriasis vulgaris	0.684	0.315
I60-I69 Cerebrovascular diseases	0.682	0.318
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.681	0.318
D05.7 Other carcinoma in situ of breast	0.681	0.319
E85 Amyloidosis	0.680	0.320
E84 Cystic fibrosis	0.680	0.320
E79 Disorders of purine and pyrimidine metabolism	0.680	0.320
E77 Disorders of glycoprotein metabolism	0.680	0.320
E76 Disorders of glycosaminoglycan metabolism	0.680	0.320
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.680	0.320
E74 Other disorders of carbohydrate metabolism	0.680	0.320
E72 Other disorders of amino-acid metabolism	0.680	0.320
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.680	0.320
E70 Disorders of aromatic amino-acid metabolism	0.680	0.320
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.680	0.320
I78 Diseases of capillaries	0.679	0.321
C20 Malignant neoplasm of rectum	0.677	0.322
M47.2 Other spondylosis with radiculopathy	0.677	0.323
E87.2 Acidosis	0.676	0.324
C26 Malignant neoplasm of other and ill-defined digestive organs	0.675	0.325
M91-M94 Chondropathies	0.675	0.325
M60-M63 Disorders of muscles	0.675	0.325
M00-M03 Infectious arthropathies	0.675	0.325
C21 Malignant neoplasm of anus and anal canal	0.674	0.326
D25.1 Intramural leiomyoma of uterus	0.673	0.327
H04.1 Other disorders of lachrymal gland	0.672	0.328
H55 Nystagmus and other irregular eye movements	0.669	0.331
H02.4 Ptosis of eyelid	0.668	0.332
D06.9 Cervix, unspecified	0.667	0.333
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.667	0.333
D18.0 Haemangioma, any site	0.667	0.333
M34 Systemic sclerosis	0.666	0.334
H33 Retinal detachments and breaks	0.665	0.335
D37.4 Colon	0.665	0.335
D46 Myelodysplastic syndromes	0.665	0.335
E88 Other metabolic disorders	0.664	0.335
H65-H75 Diseases of middle ear and mastoid	0.664	0.336
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.662	0.338
H05 Disorders of orbit	0.662	0.338
H03 Disorders of eyelid in diseases classified elsewhere	0.662	0.338
D21 Other benign neoplasms of connective and other soft tissue	0.660	0.340
M21 Other acquired deformities of limbs	0.659	0.340
Chapter XV Pregnancy, childbirth and the puerperium	0.659	0.341
D04.7 Skin of lower limb, including hip	0.659	0.341
D36 Benign neoplasm of other and unspecified sites	0.657	0.343
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.656	0.344
M25.57 Pain in joint (Ankle and foot)	0.655	0.345
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.655	0.345
H34 Retinal vascular occlusions	0.655	0.345
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.654	0.346
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.654	0.346
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.653	0.347
M45 Ankylosing spondylitis	0.652	0.347
H01.0 Blepharitis	0.652	0.347
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.652	0.348
H02.5 Other disorders affecting eyelid function	0.652	0.348
C18.0 Caecum	0.649	0.351
C91 Lymphoid leukaemia	0.649	0.351
Q60-Q64 Congenital malformations of the urinary system	0.648	0.352
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.648	0.352
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.647	0.353
I64 Stroke, not specified as haemorrhage or infarction	0.647	0.353
M49 Spondylopathies in diseases classified elsewhere	0.647	0.353
C18.7 Sigmoid colon	0.646	0.354
L71 Rosacea	0.645	0.355
E04.2 Non-toxic multinodular goitre	0.644	0.356
I71 Aortic aneurysm and dissection	0.644	0.356
E65-E68 Obesity and other hyperalimentation	0.644	0.356
I70 Atherosclerosis	0.644	0.356
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.643	0.357
M33 Dermatopolymyositis	0.643	0.357
M32 Systemic lupus erythematosus	0.643	0.357
M30 Polyarteritis nodosa and related conditions	0.643	0.357
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.643	0.357
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.642	0.358
C18.2 Ascending colon	0.642	0.358
F05 Delirium, not induced by alcohol and other psychoactive substances	0.642	0.358
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.640	0.359
E06 Thyroiditis	0.640	0.360
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.640	0.360
E00 Congenital iodine-deficiency syndrome	0.640	0.360
E02 Subclinical iodine-deficiency hypothyroidism	0.640	0.360
M25.4 Effusion of joint	0.639	0.361
F32 Depressive episode	0.639	0.361
Chapter XI Diseases of the digestive system	0.636	0.364
K70-K77 Diseases of liver	0.636	0.364
G50-G59 Nerve, nerve root and plexus disorders	0.635	0.365
M31 Other necrotising vasculopathies	0.634	0.366
D03.5 Melanoma in situ of trunk	0.634	0.366
D04.3 Skin of other and unspecified parts of face	0.633	0.366
M47.1 Other spondylosis with myelopathy	0.633	0.367
M47.0 Anterior spinal and vertebral artery compression syndromes	0.633	0.367
C44.5 Skin of trunk	0.632	0.368
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.630	0.370
C17 Malignant neoplasm of small intestine	0.630	0.370
C23 Malignant neoplasm of gallbladder	0.630	0.370
S80-S89 Injuries to the knee and lower leg	0.630	0.370
W20-W49 Exposure to inanimate mechanical forces	0.628	0.372
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.628	0.372
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.628	0.372
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.628	0.372
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.628	0.372
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.628	0.372
M47.89 Other spondylosis (Site unspecified)	0.628	0.372
E53 Deficiency of other B group vitamins	0.628	0.372
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.627	0.373
M20.2 Hallux rigidus	0.626	0.374
D26 Other benign neoplasms of uterus	0.626	0.374
D10 Benign neoplasm of mouth and pharynx	0.625	0.375
M89 Other disorders of bone	0.625	0.375
H35.7 Separation of retinal layers	0.625	0.375
H80-H83 Diseases of inner ear	0.623	0.376
I35 Nonrheumatic aortic valve disorders	0.623	0.377
E73.9 Lactose intolerance, unspecified	0.622	0.377
D33.3 Cranial nerves	0.622	0.378
H00 Hordeolum and chalazion	0.621	0.378
L60 Nail disorders	0.621	0.379
E89.0 Postprocedural hypothyroidism	0.620	0.380
M25.55 Pain in joint (Pelvic region and thigh)	0.620	0.380
M47.86 Other spondylosis (Lumbar region)	0.620	0.380
D31 Benign neoplasm of eye and adnexa	0.618	0.382
D30 Benign neoplasm of urinary organs	0.618	0.382
D29 Benign neoplasm of male genital organs	0.618	0.382
D28 Benign neoplasm of other and unspecified female genital organs	0.618	0.382
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.618	0.382
D19 Benign neoplasm of mesothelial tissue	0.618	0.382
D16 Benign neoplasm of bone and articular cartilage	0.618	0.382
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.618	0.382
D14 Benign neoplasm of middle ear and respiratory system	0.618	0.382
M47.96 Spondylosis, unspecified (Lumbar region)	0.617	0.383
C90 Multiple myeloma and malignant plasma cell neoplasms	0.617	0.383
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.614	0.386
K76 Other diseases of liver	0.614	0.386
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.612	0.387
C95 Leukaemia of unspecified cell type	0.612	0.387
C94 Other leukaemias of specified cell type	0.612	0.387
C93 Monocytic leukaemia	0.612	0.387
C88 Malignant immunoproliferative diseases	0.612	0.387
C86 Other specified types of T/NK-cell lymphoma	0.612	0.387
C84 Peripheral and cutaneous T-cell lymphomas	0.612	0.387
E07.8 Other specified disorders of thyroid	0.612	0.388
E07.1 Dyshormogenetic goitre	0.612	0.388
E07.0 Hypersecretion of calcitonin	0.612	0.388
H02.7 Other degenerative disorders of eyelid and periocular area	0.611	0.389
H02.6 Xanthelasma of eyelid	0.611	0.389
H02.2 Lagophthalmos	0.611	0.389
D32.9 Meninges, unspecified	0.610	0.390
L73 Other follicular disorders	0.609	0.390
L75 Apocrine sweat disorders	0.609	0.391
L74 Eccrine sweat disorders	0.609	0.391
L70 Acne	0.609	0.391
L68 Hypertrichosis	0.609	0.391
L67 Hair colour and hair shaft abnormalities	0.609	0.391
L66 Cicatricial alopecia [scarring hair loss]	0.609	0.391
L65 Other nonscarring hair loss	0.609	0.391
L64 Androgenic alopecia	0.609	0.391
L63 Alopecia areata	0.609	0.391
L62 Nail disorders in diseases classified elsewhere	0.609	0.391
E04.9 Non-toxic goitre, unspecified	0.609	0.391
E83.9 Disorder of mineral metabolism, unspecified	0.608	0.392
E83.8 Other disorders of mineral metabolism	0.608	0.392
E83.3 Disorders of phosphorus metabolism	0.608	0.392
E83.2 Disorders of zinc metabolism	0.608	0.392
E83.0 Disorders of copper metabolism	0.608	0.392
H32 Chorioretinal disorders in diseases classified elsewhere	0.608	0.392
H31 Other disorders of choroid	0.608	0.392
H30 Chorioretinal inflammation	0.608	0.392
Q20-Q28 Congenital malformations of the circulatory system	0.607	0.392
E80.4 Gilbert's syndrome	0.607	0.393
D11 Benign neoplasm of major salivary glands	0.605	0.394
L50 Urticaria	0.605	0.395
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.605	0.395
M46 Other inflammatory spondylopathies	0.605	0.395
D37.0 Lip, oral cavity and pharynx	0.605	0.395
H18 Other disorders of cornea	0.604	0.396
Q50-Q56 Congenital malformations of genital organs	0.604	0.396
D37.5 Rectum	0.603	0.396
X20-X29 Contact with venomous animals and plants	0.603	0.397
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.603	0.397
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.603	0.397
C81.9 Hodgkin's disease, unspecified	0.601	0.399
M67 Other disorders of synovium and tendon	0.600	0.400
I78.1 Naevus, nonneoplastic	0.600	0.400
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.600	0.400
C44.6 Skin of upper limb, including shoulder	0.599	0.401
I44 Atrioventricular and left bundle-branch block	0.599	0.401
L43.8 Other lichen planus	0.597	0.403
L43.3 Subacute (active) lichen planus	0.597	0.403
L43.2 Lichenoid drug reaction	0.597	0.403
L43.1 Bullous lichen planus	0.597	0.403
L43.0 Hypertrophic lichen planus	0.597	0.403
I73 Other peripheral vascular diseases	0.597	0.403
Y43 Primarily systemic agents	0.597	0.403
H54 Blindness and low vision	0.595	0.405
M15-M19 Arthrosis	0.595	0.405
I72 Other aneurysm	0.595	0.405
F99-F99 Unspecified mental disorder	0.594	0.406
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.594	0.406
F80-F89 Disorders of psychological development	0.594	0.406
F70-F79 Mental retardation	0.594	0.406
F60-F69 Disorders of adult personality and behaviour	0.594	0.406
F32.2 Severe depressive episode without psychotic symptoms	0.593	0.407
M86 Osteomyelitis	0.593	0.407
H33.3 Retinal breaks without detachment	0.592	0.407
H57.8 Other specified disorders of eye and adnexa	0.592	0.408
D35 Benign neoplasm of other and unspecified endocrine glands	0.592	0.408
H90-H95 Other disorders of ear	0.591	0.408
M48 Other spondylopathies	0.591	0.409
M40-M43 Deforming dorsopathies	0.591	0.409
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.590	0.410
M47.85 Other spondylosis (Thoracolumbar region)	0.590	0.410
M47.84 Other spondylosis (Thoracic region)	0.590	0.410
M47.83 Other spondylosis (Cervicothoracic region)	0.590	0.410
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.590	0.410
E10 Insulin-dependent diabetes mellitus	0.590	0.410
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.589	0.411
C38 Malignant neoplasm of heart, mediastinum and pleura	0.589	0.411
C32 Malignant neoplasm of larynx	0.589	0.411
C31 Malignant neoplasm of accessory sinuses	0.589	0.411
C30 Malignant neoplasm of nasal cavity and middle ear	0.589	0.411
C37 Malignant neoplasm of thymus	0.589	0.411
C33 Malignant neoplasm of trachea	0.589	0.411
D45 Polycythaemia vera	0.588	0.412
C18.4 Transverse colon	0.587	0.412
M24 Other specific joint derangements	0.586	0.414
I30 Acute pericarditis	0.586	0.414
D22 Melanocytic naevi	0.586	0.414
L53 Other erythematous conditions	0.586	0.414
G51 Facial nerve disorders	0.585	0.415
C18.8 Overlapping lesion of colon	0.585	0.415
C18.5 Splenic flexure	0.585	0.415
C18.3 Hepatic flexure	0.585	0.415
C18.1 Appendix	0.585	0.415
H35.5 Hereditary retinal dystrophy	0.585	0.415
H35.8 Other specified retinal disorders	0.584	0.416
D04.9 Skin, unspecified	0.582	0.417
D04.8 Skin of other sites	0.582	0.417
D04.6 Skin of upper limb, including shoulder	0.582	0.417
D04.5 Skin of trunk	0.582	0.417
D04.4 Skin of scalp and neck	0.582	0.417
D04.2 Skin of ear and external auricular canal	0.582	0.417
D04.1 Skin of eyelid, including canthus	0.582	0.417
D04.0 Skin of lip	0.582	0.417
I00-I02 Acute rheumatic fever	0.582	0.418
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.581	0.418
Q80-Q89 Other congenital malformations	0.581	0.418
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.581	0.418
Q38-Q45 Other congenital malformations of the digestive system	0.581	0.418
Q35-Q37 Cleft lip and cleft palate	0.581	0.418
Q30-Q34 Congenital malformations of the respiratory system	0.581	0.418
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.581	0.418
Q00-Q07 Congenital malformations of the nervous system	0.581	0.418
M47.87 Other spondylosis (Lumbosacral region)	0.581	0.419
D17.6 Benign lipomatous neoplasm of spermatic cord	0.581	0.419
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.580	0.420
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.580	0.420
M47.94 Spondylosis, unspecified (Thoracic region)	0.580	0.420
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.580	0.420
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.580	0.420
C34.1 Upper lobe, bronchus or lung	0.580	0.420
M22.2 Patellofemoral disorders	0.579	0.421
M80-M85 Disorders of bone density and structure	0.579	0.421
M87 Osteonecrosis	0.579	0.421
C83.3 Large cell (diffuse)	0.579	0.421
M25.9 Joint disorder, unspecified	0.578	0.422
M25.8 Other specified joint disorders	0.578	0.422
M25.6 Stiffness of joint, not elsewhere classified	0.578	0.422
M25.3 Other instability of joint	0.578	0.422
M25.2 Flail joint	0.578	0.422
M25.1 Fistula of joint	0.578	0.422
M25.0 Haemarthrosis	0.578	0.422
M65 Synovitis and tenosynovitis	0.577	0.423
F05.9 Delirium, unspecified	0.577	0.423
E87.6 Hypokalaemia	0.577	0.423
G62 Other polyneuropathies	0.576	0.423
C44.2 Skin of ear and external auricular canal	0.575	0.425
C44.0 Skin of lip	0.575	0.425
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.575	0.425
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.575	0.425
C34.2 Middle lobe, bronchus or lung	0.574	0.426
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.573	0.427
C92 Myeloid leukaemia	0.572	0.427
S70-S79 Injuries to the hip and thigh	0.572	0.428
D06.7 Other parts of cervix	0.571	0.428
D06.1 Exocervix	0.571	0.428
D06.0 Endocervix	0.571	0.428
I77.6 Arteritis, unspecified	0.572	0.428
I33 Acute and subacute endocarditis	0.571	0.429
F03 Unspecified dementia	0.571	0.429
M25.52 Pain in joint (Upper arm)	0.571	0.429
Chapter X Diseases of the respiratory system	0.571	0.429
D34 Benign neoplasm of thyroid gland	0.569	0.431
M25.50 Pain in joint (Multiple sites)	0.567	0.433
I60 Subarachnoid haemorrhage	0.566	0.433
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.566	0.434
I31 Other diseases of pericardium	0.565	0.435
E87.7 Fluid overload	0.564	0.435
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.563	0.437
K74 Fibrosis and cirrhosis of liver	0.562	0.438
H43-H45 Disorders of vitreous body and globe	0.562	0.438
C44.9 Malignant neoplasm of skin, unspecified	0.562	0.438
C44.8 Overlapping lesion of skin	0.562	0.438
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.562	0.438
I35.1 Aortic (valve) insufficiency	0.561	0.439
H65 Nonsuppurative otitis media	0.561	0.439
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.560	0.440
Y52 Agents primarily affecting the cardiovascular system	0.559	0.441
C18.6 Descending colon	0.559	0.441
I44.7 Left bundle-branch block, unspecified	0.559	0.441
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.558	0.441
D03.9 Melanoma in situ, unspecified	0.558	0.442
D03.8 Melanoma in situ of other sites	0.558	0.442
D03.7 Melanoma in situ of lower limb, including hip	0.558	0.442
D03.6 Melanoma in situ of upper limb, including shoulder	0.558	0.442
D03.4 Melanoma in situ of scalp and neck	0.558	0.442
D03.3 Melanoma in situ of other and unspecified parts of face	0.558	0.442
D03.2 Melanoma in situ of ear and external auricular canal	0.558	0.442
D03.1 Melanoma in situ of eyelid, including canthus	0.558	0.442
D03.0 Melanoma in situ of lip	0.558	0.442
I74 Arterial embolism and thrombosis	0.558	0.442
D37.9 Digestive organ, unspecified	0.558	0.442
D37.7 Other digestive organs	0.558	0.442
D37.6 Liver, gallbladder and bile ducts	0.558	0.442
D37.3 Appendix	0.558	0.442
D37.2 Small intestine	0.558	0.442
D37.1 Stomach	0.558	0.442
M90 Osteopathies in diseases classified elsewhere	0.557	0.443
I95-I99 Other and unspecified disorders of the circulatory system	0.556	0.444
W00-W19 Falls	0.556	0.444
Y43.3 Other antineoplastic drugs	0.556	0.444
V20-V29 Motorcycle rider injured in transport accident	0.555	0.445
M22.8 Other disorders of patella	0.555	0.445
G80-G83 Cerebral palsy and other paralytic syndromes	0.555	0.445
D23 Other benign neoplasms of skin	0.555	0.445
H35.4 Peripheral retinal degeneration	0.555	0.445
T15-T19 Effects of foreign body entering through natural orifice	0.554	0.446
L54 Erythema in diseases classified elsewhere	0.554	0.446
L51 Erythema multiforme	0.554	0.446
L52 Erythema nodosum	0.554	0.446
H16 Keratitis	0.554	0.446
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.554	0.446
H57.9 Disorder of eye and adnexa, unspecified	0.553	0.447
I38 Endocarditis, valve unspecified	0.553	0.447
M25.59 Pain in joint (Site unspecified)	0.552	0.447
I77.9 Disorder of arteries and arterioles, unspecified	0.552	0.448
M47.92 Spondylosis, unspecified (Cervical region)	0.552	0.448
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.551	0.448
M88 Paget's disease of bone [osteitis deformans]	0.551	0.448
H50 Other strabismus	0.551	0.449
M16 Coxarthrosis [arthrosis of hip]	0.550	0.449
C43.7 Malignant melanoma of lower limb, including hip	0.550	0.450
E27 Other disorders of adrenal gland	0.550	0.450
M35 Other systemic involvement of connective tissue	0.550	0.450
C01 Malignant neoplasm of base of tongue	0.550	0.450
E64 Sequelae of malnutrition and other nutritional deficiencies	0.550	0.450
E63 Other nutritional deficiencies	0.550	0.450
E56 Other vitamin deficiencies	0.550	0.450
E51 Thiamine deficiency	0.550	0.450
E50 Vitamin A deficiency	0.550	0.450
E60 Dietary zinc deficiency	0.550	0.450
E59 Dietary selenium deficiency	0.550	0.450
E58 Dietary calcium deficiency	0.550	0.450
E54 Ascorbic acid deficiency	0.550	0.450
E52 Niacin deficiency [pellagra]	0.550	0.450
G51.0 Bell's palsy	0.550	0.450
H01.9 Inflammation of eyelid, unspecified	0.549	0.451

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations