TreeWAS – Variant ID: rs2417820

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.001	0.999
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.013	0.987
I25.5 Ischaemic cardiomyopathy	0.000	0.047	0.953
I25.2 Old myocardial infarction	0.000	0.081	0.919
I25.4 Coronary artery aneurysm	0.000	0.169	0.831
I25.3 Aneurysm of heart	0.000	0.180	0.820
I20-I25 Ischaemic heart diseases	0.000	0.253	0.747
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.278	0.722
I25.6 Silent myocardial ischaemia	0.000	0.284	0.716
I20 Angina pectoris	0.000	0.302	0.698
I20.8 Other forms of angina pectoris	0.000	0.339	0.661
I20.9 Angina pectoris, unspecified	0.000	0.359	0.641
I23 Certain current complications following acute myocardial infarction	0.000	0.423	0.577
I21 Acute myocardial infarction	0.000	0.481	0.519
I24 Other acute ischaemic heart diseases	0.000	0.491	0.509
I20.1 Angina pectoris with documented spasm	0.000	0.524	0.476
I24.8 Other forms of acute ischaemic heart disease	0.000	0.537	0.463
I25.0 Atherosclerotic cardiovascular disease, so described	0.001	0.540	0.459
I23.8 Other current complications following acute myocardial infarction	0.000	0.544	0.456
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.556	0.444
I22 Subsequent myocardial infarction	0.000	0.563	0.437
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.586	0.414
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.586	0.414
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.586	0.414
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.586	0.414
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.586	0.414
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.586	0.414
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.586	0.414
I10-I15 Hypertensive diseases	0.000	0.587	0.413
I24.1 Dressler's syndrome	0.000	0.590	0.410
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.613	0.387
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.620	0.380
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.628	0.372
I21.9 Acute myocardial infarction, unspecified	0.000	0.654	0.346
I22.8 Subsequent myocardial infarction of other sites	0.000	0.670	0.330
I12 Hypertensive renal disease	0.000	0.680	0.320
I21.4 Acute subendocardial myocardial infarction	0.000	0.685	0.315
I12.9 Hypertensive renal disease without renal failure	0.000	0.700	0.300
I13 Hypertensive heart and renal disease	0.000	0.704	0.296
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.713	0.287
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.714	0.286
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.717	0.283
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.734	0.266
I11 Hypertensive heart disease	0.000	0.771	0.229
I15 Secondary hypertension	0.000	0.773	0.227
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.787	0.212
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.787	0.212
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.787	0.212
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.787	0.212
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.793	0.207
Chapter IX Diseases of the circulatory system	0.000	0.797	0.203
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.828	0.171
I15.8 Other secondary hypertension	0.000	0.837	0.163
I15.2 Hypertension secondary to endocrine disorders	0.000	0.837	0.163
I15.0 Renovascular hypertension	0.000	0.844	0.155
I00-I02 Acute rheumatic fever	0.000	0.852	0.148
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.859	0.141
I15.1 Hypertension secondary to other renal disorders	0.000	0.860	0.140
I15.9 Seconday hypertension, unspecified	0.000	0.861	0.138
I20.0 Unstable angina	0.000	0.873	0.127
I00 Rheumatic fever without mention of heart involvement	0.000	0.891	0.109
I02 Rheumatic chorea	0.000	0.893	0.106
I01 Rheumatic fever with heart involvement	0.000	0.893	0.106
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.918	0.081
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.919	0.081
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.923	0.076
I01.8 Other acute rheumatic heart disease	0.000	0.923	0.076
I01.2 Acute rheumatic myocarditis	0.000	0.923	0.076
I01.1 Acute rheumatic endocarditis	0.000	0.923	0.076
I01.0 Acute rheumatic pericarditis	0.000	0.923	0.076
I02.9 Rheumatic chorea without heart involvement	0.000	0.923	0.076
I02.0 Rheumatic chorea with heart involvement	0.000	0.923	0.076
I28 Other diseases of pulmonary vessels	0.000	0.942	0.058
I28.8 Other specified diseases of pulmonary vessels	0.000	0.953	0.047
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.955	0.045
I28.1 Aneurysm of pulmonary artery	0.000	0.958	0.042
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.958	0.042
I27 Other pulmonary heart diseases	0.000	0.958	0.042
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.965	0.034
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.968	0.032
I27.9 Pulmonary heart disease, unspecified	0.000	0.968	0.032
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.968	0.032
I26 Pulmonary embolism	0.000	0.970	0.030
I27.1 Kyphoscoliotic heart disease	0.000	0.970	0.030
I27.8 Other specified pulmonary heart diseases	0.000	0.970	0.029
I27.0 Primary pulmonary hypertension	0.000	0.971	0.029
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.972	0.028
C44.0 Skin of lip	0.027	0.973	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.976	0.024
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.977	0.023
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.977	0.023
I98.0 Cardiovascular syphilis	0.000	0.977	0.023
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.977	0.023
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.978	0.022
I05-I09 Chronic rheumatic heart diseases	0.001	0.978	0.021
I97.0 Postcardiotomy syndrome	0.000	0.979	0.021
I12.0 Hypertensive renal disease with renal failure	0.000	0.979	0.021
I97.1 Other functional disturbances following cardiac surgery	0.000	0.979	0.021
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.980	0.020
J32.0 Chronic maxillary sinusitis	0.000	0.981	0.019
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.982	0.017
I06 Rheumatic aortic valve diseases	0.001	0.985	0.014
I99 Other and unspecified disorders of circulatory system	0.000	0.985	0.014
I09 Other rheumatic heart diseases	0.001	0.985	0.014
J32 Chronic sinusitis	0.000	0.987	0.013
I27.2 Other secondary pulmonary hypertension	0.000	0.988	0.012
J32.2 Chronic ethmoidal sinusitis	0.000	0.988	0.012
J32.1 Chronic frontal sinusitis	0.000	0.988	0.011
I06.0 Rheumatic aortic stenosis	0.001	0.989	0.011
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.989	0.011
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.989	0.010
I06.8 Other rheumatic aortic valve diseases	0.001	0.989	0.010
I06.2 Rheumatic aortic stenosis with insufficiency	0.001	0.989	0.010
I71 Aortic aneurysm and dissection	0.000	0.989	0.011
I07 Rheumatic tricuspid valve diseases	0.001	0.989	0.010
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.989	0.011
I09.8 Other specified rheumatic heart diseases	0.001	0.989	0.010
I09.2 Chronic rheumatic pericarditis	0.001	0.989	0.010
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.989	0.010
I09.0 Rheumatic myocarditis	0.001	0.989	0.010
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.989	0.011
J32.3 Chronic sphenoidal sinusitis	0.000	0.990	0.010
C81.9 Hodgkin's disease, unspecified	0.000	0.990	0.010
I06.1 Rheumatic aortic insufficiency	0.001	0.990	0.009
Z63.0 Problems in relationship with spouse or partner	0.010	0.990	0.000
Z63 Other problems related to primary support group, including family circumstances	0.009	0.991	0.000
I09.9 Rheumatic heart disease, unspecified	0.001	0.991	0.009
Z63.7 Other stressful life events affecting family and household	0.009	0.991	0.000
J32.9 Chronic sinusitis, unspecified	0.000	0.991	0.009
J32.8 Other chronic sinusitis	0.000	0.991	0.009
J32.4 Chronic pansinusitis	0.000	0.991	0.009
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.991	0.009
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.992	0.008
Z63.8 Other specified problems related to primary support group	0.008	0.992	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.992	0.008
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.992	0.008
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.992	0.008
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.992	0.008
I07.9 Tricuspid valve disease, unspecified	0.001	0.992	0.007
I07.8 Other tricuspid valve diseases	0.001	0.992	0.007
I07.2 Tricuspid stenosis with insufficiency	0.001	0.992	0.007
I07.0 Tricuspid stenosis	0.001	0.992	0.007
Z63.6 Dependent relative needing care at home	0.008	0.992	0.000
E11.5 With peripheral circulatory complications	0.008	0.992	0.000
S02.20 Fracture of nasal bones (closed)	0.008	0.992	0.000
H18.8 Other specified disorders of cornea	0.000	0.992	0.008
Z63.4 Disappearance and death of family member	0.008	0.992	0.000
H18.4 Corneal degeneration	0.000	0.993	0.007
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.993	0.007
Z63.9 Problem related to primary support group, unspecified	0.007	0.993	0.000
Z63.3 Absence of family member	0.007	0.993	0.000
Z63.2 Inadequate family support	0.007	0.993	0.000
Z63.1 Problems in relationship with parents and in-laws	0.007	0.993	0.000
H53.0 Amblyopia ex anopsia	0.007	0.993	0.000
H18 Other disorders of cornea	0.000	0.993	0.007
Z63.5 Disruption of family by separation and divorce	0.007	0.993	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.994	0.006
H18.6 Keratoconus	0.000	0.994	0.006
M22.8 Other disorders of patella	0.006	0.994	0.000
I71.0 Dissection of aorta [any part]	0.000	0.994	0.006
E11.6 With other specified complications	0.006	0.994	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.994	0.006
E21.0 Primary hyperparathyroidism	0.000	0.994	0.006
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.994	0.006
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.006	0.994	0.000
I70 Atherosclerosis	0.000	0.995	0.005
I74 Arterial embolism and thrombosis	0.000	0.995	0.005
H18.7 Other corneal deformities	0.000	0.995	0.005
Y45.0 Opioids and related analgesics	0.000	0.995	0.005
I73 Other peripheral vascular diseases	0.000	0.995	0.005
N48.6 Balanitis xerotica obliterans	0.005	0.995	0.000
I05 Rheumatic mitral valve diseases	0.002	0.995	0.003
M86.9 Osteomyelitis, unspecified	0.005	0.995	0.000
I78 Diseases of capillaries	0.000	0.995	0.005
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.995	0.005
H18.0 Corneal pigmentations and deposits	0.000	0.995	0.005
I79.1 Aortitis in diseases classified elsewhere	0.000	0.995	0.004
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.995	0.004
H18.1 Bullous keratopathy	0.000	0.995	0.004
E78.0 Pure hypercholesterolaemia	0.000	0.995	0.005
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.995	0.004
M22.2 Patellofemoral disorders	0.005	0.995	0.000
I08 Multiple valve diseases	0.000	0.996	0.004
S02.2 Fracture of nasal bones	0.004	0.996	0.000
E11 Non-insulin-dependent diabetes mellitus	0.004	0.996	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.996	0.004
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.996	0.004
M22 Disorders of patella	0.004	0.996	0.000
F06.7 Mild cognitive disorder	0.004	0.996	0.000
H18.9 Disorder of cornea, unspecified	0.000	0.996	0.004
H18.3 Changes in corneal membranes	0.000	0.996	0.004
I70.1 Atherosclerosis of renal artery	0.000	0.996	0.004
M86.96 Osteomyelitis, unspecified (Lower leg)	0.004	0.996	0.000
Z89.4 Acquired absence of foot and ankle	0.004	0.996	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.996	0.004
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.996	0.004
E11.2 With renal complications	0.004	0.996	0.000
Z89.5 Acquired absence of leg at or below knee	0.004	0.996	0.000
Z89 Acquired absence of limb	0.004	0.996	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.004	0.996	0.000
H18.2 Other corneal oedema	0.000	0.996	0.004
I70.9 Generalised and unspecified atherosclerosis	0.000	0.996	0.004
I70.8 Atherosclerosis of other arteries	0.000	0.996	0.004
E11.3 With ophthalmic complications	0.004	0.996	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
I05.8 Other mitral valve diseases	0.001	0.996	0.002
C78.7 Secondary malignant neoplasm of liver	0.000	0.996	0.004
M86 Osteomyelitis	0.004	0.996	0.000
I73.0 Raynaud's syndrome	0.000	0.996	0.004
N43.3 Hydrocele, unspecified	0.004	0.996	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.004	0.996	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.004	0.996	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.004	0.996	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.004	0.996	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.996	0.004
E34 Other endocrine disorders	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.996	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.996	0.004
I78.9 Disease of capillaries, unspecified	0.000	0.996	0.003
Z74.0 Reduced mobility	0.000	0.996	0.004
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.996	0.003
S02.21 Fracture of nasal bones (open)	0.003	0.996	0.000
Z89.6 Acquired absence of leg above knee	0.004	0.996	0.000
I70.0 Atherosclerosis of aorta	0.000	0.996	0.003
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.996	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.003	0.996	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.003	0.996	0.000
E34.8 Other specified endocrine disorders	0.003	0.997	0.000
M07.3 Other psoriatic arthropathies	0.000	0.997	0.003
E21.2 Other hyperparathyroidism	0.003	0.997	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.997	0.003
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.997	0.003
E11.7 With multiple complications	0.003	0.997	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.997	0.003
I72 Other aneurysm	0.000	0.997	0.003
N02.8 Other	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.997	0.002
E24 Cushing's syndrome	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.997	0.002
M22.3 Other derangements of patella	0.003	0.997	0.000
M22.1 Recurrent subluxation of patella	0.003	0.997	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.997	0.003
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.997	0.003
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
I08.8 Other multiple valve diseases	0.000	0.997	0.003
E11.0 With coma	0.003	0.997	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.997	0.003
M86.6 Other chronic osteomyelitis	0.003	0.997	0.000
R12 Heartburn	0.003	0.997	0.000
I78.8 Other diseases of capillaries	0.000	0.997	0.003
M22.0 Recurrent dislocation of patella	0.003	0.997	0.000
H47.3 Other disorders of optic disk	0.003	0.997	0.000
M22.9 Disorder of patella, unspecified	0.003	0.997	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.003	0.997	0.000
M86.1 Other acute osteomyelitis	0.003	0.997	0.000
I05.0 Mitral stenosis	0.002	0.997	0.001
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.003	0.997	0.000
Z89.1 Acquired absence of hand and wrist	0.003	0.997	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.997	0.003
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.997	0.003
I07.1 Tricuspid insufficiency	0.002	0.997	0.002
E34.0 Carcinoid syndrome	0.003	0.997	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.997	0.003
M22.4 Chondromalacia patellae	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.997	0.003
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.997	0.003
M86.5 Other chronic haematogenous osteomyelitis	0.003	0.997	0.000
M86.3 Chronic multifocal osteomyelitis	0.003	0.997	0.000
M86.2 Subacute osteomyelitis	0.003	0.997	0.000
M86.0 Acute haematogenous osteomyelitis	0.003	0.997	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.003	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.997	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.997	0.000
Z89.9 Acquired absence of limb, unspecified	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.997	0.003
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.997	0.003
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
I05.9 Mitral valve disease, unspecified	0.002	0.997	0.001
I74.5 Embolism and thrombosis of iliac artery	0.000	0.997	0.003
M86.8 Other osteomyelitis	0.003	0.997	0.000
I72.9 Aneurysm of unspecified site	0.000	0.997	0.003
E11.8 With unspecified complications	0.003	0.997	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.997	0.003
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.997	0.003
Z89.2 Acquired absence of upper limb above wrist	0.003	0.997	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.997	0.003
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.997	0.003
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.997	0.003
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.997	0.003
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.003	0.997	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.003	0.997	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.003	0.997	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.003	0.997	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.003	0.997	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.003	0.997	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.003	0.997	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.003	0.997	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.003	0.997	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.997	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.997	0.003
I72.1 Aneurysm of artery of upper extremity	0.000	0.997	0.003
E25 Adrenogenital disorders	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.997	0.003
C02.9 Tongue, unspecified	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.003	0.997	0.000
E11.1 With ketoacidosis	0.003	0.997	0.000
C20 Malignant neoplasm of rectum	0.000	0.997	0.003
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.997	0.003
M22.10 Recurrent subluxation of patella, unspecified knee	0.002	0.997	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.68 Other chronic osteomyelitis (Other)	0.002	0.997	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.002	0.997	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.002	0.997	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.002	0.997	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.002
M21.1 Varus deformity, not elsewhere classified	0.003	0.997	0.000
Z58.8 Other problems related to physical environment	0.003	0.997	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.997	0.002
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.997	0.000
C81 Hodgkin's disease	0.000	0.997	0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.997	0.000
I72.0 Aneurysm of carotid artery	0.000	0.997	0.002
M86.19 Other acute osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.18 Other acute osteomyelitis (Other)	0.002	0.997	0.000
M86.16 Other acute osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.14 Other acute osteomyelitis (Hand)	0.002	0.997	0.000
M86.13 Other acute osteomyelitis (Forearm)	0.002	0.997	0.000
M86.12 Other acute osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.11 Other acute osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.10 Other acute osteomyelitis (Multiple sites)	0.002	0.997	0.000
I78.1 Naevus, nonneoplastic	0.000	0.997	0.003
K50.9 Crohn's disease, unspecified	0.003	0.997	0.000
S70.0 Contusion of hip	0.000	0.997	0.003
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.997	0.002
T23 Burn and corrosion of wrist and hand	0.000	0.997	0.003
Z58 Problems related to physical environment	0.002	0.997	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.998	0.002
K50.8 Other Crohn's disease	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
Z56 Problems related to employment and unemployment	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.002	0.998	0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.08 Acute haematogenous osteomyelitis (Other)	0.002	0.998	0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.04 Acute haematogenous osteomyelitis (Hand)	0.002	0.998	0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.002	0.998	0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.29 Subacute osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.28 Subacute osteomyelitis (Other)	0.002	0.998	0.000
M86.27 Subacute osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.26 Subacute osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.24 Subacute osteomyelitis (Hand)	0.002	0.998	0.000
M86.23 Subacute osteomyelitis (Forearm)	0.002	0.998	0.000
M86.22 Subacute osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.21 Subacute osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.20 Subacute osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.38 Chronic multifocal osteomyelitis (Other)	0.002	0.998	0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.34 Chronic multifocal osteomyelitis (Hand)	0.002	0.998	0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.002	0.998	0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.002	0.998	0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.002	0.998	0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.002	0.998	0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.998	0.002
M86.87 Other osteomyelitis (Ankle and foot)	0.002	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.000	0.998	0.002
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.998	0.002
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.998	0.002
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.998	0.002
I77 Other disorders of arteries and arterioles	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
E29 Testicular dysfunction	0.002	0.998	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.88 Other osteomyelitis (Other)	0.002	0.998	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.84 Other osteomyelitis (Hand)	0.002	0.998	0.000
M86.83 Other osteomyelitis (Forearm)	0.002	0.998	0.000
M86.82 Other osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.81 Other osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.80 Other osteomyelitis (Multiple sites)	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
Z56.6 Other physical and mental strain related to work	0.002	0.998	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
C02.4 Lingual tonsil	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.002
T79.8 Other early complications of trauma	0.002	0.998	0.000
C81.2 Mixed cellularity	0.000	0.998	0.002
O69.8 Labour and delivery complicated by other cord complications	0.002	0.998	0.000
Z65 Problems related to other psychosocial circumstances	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.002	0.998	0.000
Z55 Problems related to education and literacy	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
E20 Hypoparathyroidism	0.002	0.998	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.998	0.002
S70.1 Contusion of thigh	0.000	0.998	0.002
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
I72.2 Aneurysm of renal artery	0.000	0.998	0.002
I95 Hypotension	0.000	0.998	0.002
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
T23.1 Burn of first degree of wrist and hand	0.000	0.998	0.002
Z58.5 Exposure to other pollution	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.002	0.998	0.000
M86.86 Other osteomyelitis (Lower leg)	0.002	0.998	0.000
C81.7 Other Hodgkin's disease	0.000	0.998	0.002
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.998	0.002
C81.3 Lymphocytic depletion	0.000	0.998	0.002
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.998	0.002
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
G80.1 Spastic diplegia	0.002	0.998	0.000
N48.2 Other inflammatory disorders of penis	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
I77.2 Rupture of artery	0.000	0.998	0.002
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
T23.7 Corrosion of third degree of wrist and hand	0.000	0.998	0.002
T23.6 Corrosion of second degree of wrist and hand	0.000	0.998	0.002
T23.5 Corrosion of first degree of wrist and hand	0.000	0.998	0.002
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.998	0.002
Z58.9 Problem related to physical environment, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations