TreeWAS – Variant ID: rs245914

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y95 Nosocomial condition	0.000	0.960	0.040
L82 Seborrhoeic keratosis	0.000	0.965	0.035
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.000	0.984	0.016
S01.0 Open wound of scalp	0.000	0.986	0.014
S01.3 Open wound of ear	0.000	0.987	0.013
S01 Open wound of head	0.000	0.988	0.012
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.000	0.988	0.012
Y98 Lifestyle-related condition	0.000	0.988	0.012
Y97 Environmental-pollution-related condition	0.000	0.988	0.012
Y96 Work-related condition	0.000	0.988	0.012
Y91 Evidence of alcohol involvement determined by level of intoxication	0.000	0.989	0.011
D07.5 Prostate	0.011	0.989	0.000
S01.9 Open wound of head, part unspecified	0.000	0.989	0.010
S01.8 Open wound of other parts of head	0.000	0.990	0.010
S01.1 Open wound of eyelid and periocular area	0.000	0.990	0.010
S01.7 Multiple open wounds of head	0.000	0.990	0.010
Y90.9 Presence of alcohol in blood, level not specified	0.000	0.991	0.008
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.000	0.991	0.008
Y90.7 Blood alcohol level of 200-239 mg/100 ml	0.000	0.991	0.008
Y90.6 Blood alcohol level of 120-199 mg/100 ml	0.000	0.991	0.008
Y90.5 Blood alcohol level of 100-119 mg/100 ml	0.000	0.991	0.008
Y90.4 Blood alcohol level of 80-99 mg/100 ml	0.000	0.991	0.008
Y90.3 Blood alcohol level of 60-79 mg/100 ml	0.000	0.991	0.008
Y90.2 Blood alcohol level of 40-59 mg/100 ml	0.000	0.991	0.008
Y90.1 Blood alcohol level of 20-39 mg/100 ml	0.000	0.991	0.008
Y90.0 Blood alcohol level of less than 20 mg/100 ml	0.000	0.991	0.008
Y91.3 Very severe alcohol intoxication	0.000	0.992	0.008
Y91.2 Severe alcohol intoxication	0.000	0.992	0.008
Y91.1 Moderate alcohol intoxication	0.000	0.992	0.008
Y91.0 Mild alcohol intoxication	0.000	0.992	0.008
S01.4 Open wound of cheek and temporomandibular area	0.000	0.992	0.008
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.992	0.008
D07 Carcinoma in situ of other and unspecified genital organs	0.008	0.992	0.000
D07.1 Vulva	0.008	0.992	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.008	0.992	0.000
G12.2 Motor neuron disease	0.007	0.993	0.000
S01.2 Open wound of nose	0.000	0.993	0.007
S01.5 Open wound of lip and oral cavity	0.000	0.993	0.007
D07.4 Penis	0.006	0.994	0.000
E10.4 With neurological complications	0.000	0.994	0.006
D07.6 Other and unspecified male genital organs	0.006	0.994	0.000
D07.3 Other and unspecified female genital organs	0.006	0.994	0.000
D07.0 Endometrium	0.006	0.994	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.005	0.995	0.000
D07.2 Vagina	0.005	0.995	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.005	0.995	0.000
E21.0 Primary hyperparathyroidism	0.005	0.995	0.000
E21.3 Hyperparathyroidism, unspecified	0.005	0.995	0.000
E10.5 With peripheral circulatory complications	0.000	0.995	0.005
E21.5 Disorder of parathyroid gland, unspecified	0.005	0.995	0.000
K62.4 Stenosis of anus and rectum	0.004	0.996	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.996	0.004
E21.4 Other specified disorders of parathyroid gland	0.004	0.996	0.000
E21.2 Other hyperparathyroidism	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
Q76.0 Spina bifida occulta	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
G12 Spinal muscular atrophy and related syndromes	0.004	0.996	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.996	0.004
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
Q43.8 Other specified congenital malformations of intestine	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.996	0.000
E10.8 With unspecified complications	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
H93.1 Tinnitus	0.000	0.997	0.003
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.997	0.003
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.003	0.997	0.000
E10.0 With coma	0.000	0.997	0.003
E10.7 With multiple complications	0.000	0.997	0.003
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
C02.1 Border of tongue	0.003	0.997	0.000
L43.9 Lichen planus, unspecified	0.000	0.997	0.003
Q66 Congenital deformities of feet	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
E10.1 With ketoacidosis	0.000	0.997	0.003
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.003	0.997	0.000
G12.9 Spinal muscular atrophy, unspecified	0.003	0.997	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.003	0.997	0.000
G12.1 Other inherited spinal muscular atrophy	0.003	0.997	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.003	0.997	0.000
E10.2 With renal complications	0.000	0.997	0.003
E23.0 Hypopituitarism	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
M20.0 Deformity of finger(s)	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
E10.9 Without complications	0.000	0.997	0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
Q51.3 Bicornate uterus	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
H54.4 Blindness, one eye	0.000	0.997	0.003
Q51.2 Other doubling of uterus	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
E10.6 With other specified complications	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
Q85.9 Phakomatosis, unspecified	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Z50.2 Alcohol rehabilitation	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
B44 Aspergillosis	0.000	0.997	0.003
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.997	0.003
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
E10.3 With ophthalmic complications	0.000	0.997	0.003
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.997	0.000
Q84 Other congenital malformations of integument	0.002	0.997	0.000
Q81 Epidermolysis bullosa	0.002	0.997	0.000
Q80 Congenital ichthyosis	0.002	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.997	0.000
Q66.5 Congenital pes planus	0.002	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.997	0.000
Q66.2 Metatarsus varus	0.002	0.997	0.000
Q66.1 Talipes calcaneovarus	0.002	0.997	0.000
Q66.0 Talipes equinovarus	0.002	0.997	0.000
D37.7 Other digestive organs	0.000	0.997	0.003
D59.1 Other autoimmune haemolytic anaemias	0.000	0.997	0.003
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.997	0.000
Q85.1 Tuberous sclerosis	0.002	0.997	0.000
E23.6 Other disorders of pituitary gland	0.002	0.997	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.997	0.000
D37.5 Rectum	0.000	0.997	0.003
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.997	0.000
E22.1 Hyperprolactinaemia	0.002	0.997	0.000
R45.1 Restlessness and agitation	0.000	0.997	0.003
Q39.4 Oesophageal web	0.002	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.997	0.000
Q63.2 Ectopic kidney	0.002	0.997	0.000
Q74.1 Congenital malformation of knee	0.002	0.997	0.000
E29 Testicular dysfunction	0.002	0.997	0.000
B44.9 Aspergillosis, unspecified	0.000	0.997	0.002
C67.9 Bladder, unspecified	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.997	0.000
Q51.4 Unicornate uterus	0.002	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.997	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
D37.1 Stomach	0.000	0.998	0.002
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.998	0.002
C02.2 Ventral surface of tongue	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.002	0.998	0.000
Q89.8 Other specified congenital malformations	0.002	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q89.4 Conjoined twins	0.002	0.998	0.000
Q89.3 Situs inversus	0.002	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.998	0.000
Q89.0 Congenital malformations of spleen	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.998	0.002
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
B44.8 Other forms of aspergillosis	0.000	0.998	0.002
B44.7 Disseminated aspergillosis	0.000	0.998	0.002
B44.2 Tonsillar aspergillosis	0.000	0.998	0.002
B44.0 Invasive pulmonary aspergillosis	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
Q96.8 Other variants of Turner's syndrome	0.002	0.998	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.002	0.998	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.002	0.998	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.002	0.998	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.002	0.998	0.000
Q96.0 Karyotype 45,X	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.002	0.998	0.000
Q80.8 Other congenital ichthyosis	0.002	0.998	0.000
Q80.4 Harlequin foetus	0.002	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.998	0.000
Q80.2 Lamellar ichthyosis	0.002	0.998	0.000
Q80.1 X-linked ichthyosis	0.002	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.998	0.000
Q84.6 Other congenital malformations of nails	0.002	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.998	0.000
Q84.4 Congenital leukonychia	0.002	0.998	0.000
Q84.3 Anonychia	0.002	0.998	0.000
Q84.2 Other congenital malformations of hair	0.002	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.002	0.998	0.000
Q84.0 Congenital alopecia	0.002	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.002	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.002	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.002	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.002	0.998	0.000
E28 Ovarian dysfunction	0.002	0.998	0.001
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.998	0.002
Q14.1 Congenital malformation of retina	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations