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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2507982
log Bayes Factor = 50.9065
Chromosome 6   position 31,346,193  (GRCh37) Explore rs2507982 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.002 0.998
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
E11 Non-insulin-dependent diabetes mellitus
0.000 0.003 0.997
E14 Unspecified diabetes mellitus
0.000 0.004 0.996
E70-E90 Metabolic disorders
0.000 0.005 0.995
E05.9 Thyrotoxicosis, unspecified
0.000 0.005 0.995
E14.9 Without complications
0.000 0.011 0.989
E10.1 With ketoacidosis
0.000 0.012 0.988
E11.9 Without complications
0.000 0.013 0.987
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.027 0.973
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.033 0.967
K51 Ulcerative colitis
0.959 0.041 0.000
K51.9 Ulcerative colitis, unspecified
0.957 0.043 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.050 0.950
E16 Other disorders of pancreatic internal secretion
0.000 0.056 0.944
E10.4 With neurological complications
0.000 0.058 0.942
K51.3 Ulcerative (chronic) rectosigmoiditis
0.940 0.060 0.000
I10 Essential (primary) hypertension
0.000 0.060 0.940
E11.1 With ketoacidosis
0.000 0.072 0.928
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.072 0.928
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.079 0.921
E16.2 Hypoglycaemia, unspecified
0.000 0.084 0.916
K51.4 Pseudopolyposis of colon
0.914 0.086 0.000
E11.0 With coma
0.000 0.104 0.896
E78.8 Other disorders of lipoprotein metabolism
0.000 0.105 0.895
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.107 0.893
K51.8 Other ulcerative colitis
0.882 0.118 0.000
E14.3 With ophthalmic complications
0.000 0.122 0.878
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.129 0.871
E07 Other disorders of thyroid
0.000 0.131 0.869
E10.8 With unspecified complications
0.000 0.141 0.859
G35-G37 Demyelinating diseases of the central nervous system
0.857 0.143 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.156 0.844
E10.2 With renal complications
0.000 0.160 0.840
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.167 0.833
E85 Amyloidosis
0.000 0.167 0.833
K51.0 Ulcerative (chronic) enterocolitis
0.825 0.175 0.000
G37 Other demyelinating diseases of central nervous system
0.818 0.182 0.000
K51.2 Ulcerative (chronic) proctitis
0.818 0.182 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.183 0.817
E78.1 Pure hyperglyceridaemia
0.000 0.188 0.812
E20-E35 Disorders of other endocrine glands
0.000 0.189 0.811
E07.9 Disorder of thyroid, unspecified
0.000 0.204 0.796
K51.5 Mucosal proctocolitis
0.795 0.205 0.000
E16.1 Other hypoglycaemia
0.000 0.213 0.787
G37.9 Demyelinating disease of central nervous system, unspecified
0.787 0.213 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.221 0.779
E10.0 With coma
0.000 0.235 0.765
E11.2 With renal complications
0.000 0.235 0.765
E10.6 With other specified complications
0.000 0.239 0.761
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.241 0.759
E11.3 With ophthalmic complications
0.000 0.243 0.757
E14.4 With neurological complications
0.000 0.248 0.752
E10.5 With peripheral circulatory complications
0.000 0.252 0.748
E05.8 Other thyrotoxicosis
0.000 0.260 0.740
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.264 0.735
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.273 0.727
I10-I15 Hypertensive diseases
0.000 0.278 0.722
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E28 Ovarian dysfunction
0.000 0.284 0.716
E78.6 Lipoprotein deficiency
0.000 0.284 0.716
E78.3 Hyperchylomicronaemia
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E11.7 With multiple complications
0.000 0.285 0.715
E14.8 With unspecified complications
0.000 0.286 0.714
E14.7 With multiple complications
0.000 0.286 0.714
E14.6 With other specified complications
0.000 0.286 0.714
E14.2 Withrenal complications
0.000 0.286 0.714
E14.1 With ketoacidosis
0.000 0.286 0.714
E14.0 With coma
0.000 0.286 0.714
E77 Disorders of glycoprotein metabolism
0.000 0.287 0.713
E76 Disorders of glycosaminoglycan metabolism
0.000 0.287 0.713
E72 Other disorders of amino-acid metabolism
0.000 0.287 0.713
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.287 0.713
E70 Disorders of aromatic amino-acid metabolism
0.000 0.287 0.713
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.287 0.713
E84 Cystic fibrosis
0.000 0.297 0.703
E79 Disorders of purine and pyrimidine metabolism
0.000 0.297 0.702
E78.4 Other hyperlipidaemia
0.000 0.301 0.699
E11.5 With peripheral circulatory complications
0.000 0.302 0.698
E85.9 Amyloidosis, unspecified
0.000 0.305 0.695
E15 Nondiabetic hypoglycaemic coma
0.000 0.307 0.693
E13 Other specified diabetes mellitus
0.000 0.307 0.693
E23 Hypofunction and other disorders of pituitary gland
0.000 0.312 0.688
E03.8 Other specified hypothyroidism
0.000 0.318 0.682
E06 Thyroiditis
0.000 0.319 0.681
E40-E46 Malnutrition
0.000 0.321 0.679
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.323 0.677
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.323 0.677
E16.4 Abnormal secretion of gastrin
0.000 0.323 0.677
E16.3 Increased secretion of glucagon
0.000 0.323 0.677
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.325 0.675
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.334 0.666
G37.8 Other specified demyelinating diseases of central nervous system
0.665 0.335 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.335 0.665
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.339 0.661
E85.4 Organ-limited amyloidosis
0.000 0.344 0.656
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.345 0.655
E73 Lactose intolerance
0.000 0.347 0.653
E11.8 With unspecified complications
0.000 0.350 0.650
K51.1 Ulcerative (chronic) ileocolitis
0.647 0.353 0.000
E29 Testicular dysfunction
0.000 0.357 0.643
I12 Hypertensive renal disease
0.000 0.361 0.639
E11.6 With other specified complications
0.000 0.364 0.636
E24 Cushing's syndrome
0.000 0.366 0.634
E07.1 Dyshormogenetic goitre
0.000 0.377 0.623
E07.0 Hypersecretion of calcitonin
0.000 0.377 0.623
G36 Other acute disseminated demyelination
0.615 0.385 0.000
M06 Other rheumatoid arthritis
0.000 0.390 0.610
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.395 0.605
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.395 0.605
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.395 0.605
E74.2 Disorders of galactose metabolism
0.000 0.395 0.605
E74.1 Disorders of fructose metabolism
0.000 0.395 0.605
E74.0 Glycogen storage disease
0.000 0.395 0.605
E85.8 Other amyloidosis
0.000 0.403 0.597
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.403 0.597
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.403 0.597
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.403 0.597
E22 Hyperfunction of pituitary gland
0.000 0.411 0.589
G37.5 Concentric sclerosis [Balo]
0.586 0.414 0.000
G37.4 Subacute necrotising myelitis
0.586 0.414 0.000
G37.2 Central pontine myelinolysis
0.586 0.414 0.000
G37.1 Central demyelination of corpus callosum
0.586 0.414 0.000
G37.0 Diffuse sclerosis
0.586 0.414 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.414 0.585
I12.9 Hypertensive renal disease without renal failure
0.000 0.419 0.581
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.419 0.581
E32 Diseases of thymus
0.000 0.419 0.581
E31 Polyglandular dysfunction
0.000 0.419 0.581
E30 Disorders of puberty, not elsewhere classified
0.000 0.419 0.581
E25 Adrenogenital disorders
0.000 0.419 0.581
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.421 0.579
E26 Hyperaldosteronism
0.000 0.429 0.571
E85.3 Secondary systemic amyloidosis
0.000 0.432 0.568
M06.3 Rheumatoid nodule
0.000 0.436 0.564
E50-E64 Other nutritional deficiencies
0.000 0.437 0.562
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.438 0.562
J45.9 Asthma, unspecified
0.000 0.440 0.560
E83 Disorders of mineral metabolism
0.298 0.442 0.260
E07.8 Other specified disorders of thyroid
0.000 0.446 0.554
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.450 0.549
M45 Ankylosing spondylitis
0.000 0.463 0.537
I15 Secondary hypertension
0.000 0.465 0.535
I11 Hypertensive heart disease
0.000 0.473 0.527
E23.6 Other disorders of pituitary gland
0.000 0.475 0.525
E29.1 Testicular hypofunction
0.000 0.476 0.524
E23.2 Diabetes insipidus
0.000 0.480 0.520
I13 Hypertensive heart and renal disease
0.000 0.482 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E28.9 Ovarian dysfunction, unspecified
0.000 0.486 0.514
E28.8 Other ovarian dysfunction
0.000 0.486 0.514
E28.1 Androgen excess
0.000 0.486 0.514
E28.0 Oestrogen excess
0.000 0.486 0.514
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.488 0.511
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.488 0.511
E70.3 Albinism
0.000 0.488 0.511
E70.2 Disorders of tyrosine metabolism
0.000 0.488 0.511
E70.1 Other hyperphenylalaninaemias
0.000 0.488 0.511
E70.0 Classical phenylketonuria
0.000 0.488 0.511
E71.3 Disorders of fatty-acid metabolism
0.000 0.488 0.511
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.488 0.511
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.488 0.511
E71.0 Maple-syrup-urine disease
0.000 0.488 0.511
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.488 0.511
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.488 0.511
E72.5 Disorders of glycine metabolism
0.000 0.488 0.511
E72.4 Disorders of ornithine metabolism
0.000 0.488 0.511
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.488 0.511
E72.2 Disorders of urea cycle metabolism
0.000 0.488 0.511
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.488 0.511
E72.0 Disorders of amino-acid transport
0.000 0.488 0.511
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.488 0.511
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.488 0.511
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.488 0.511
E76.2 Other mucopolysaccharidoses
0.000 0.488 0.511
E76.1 Mucopolysaccharidosis, type II
0.000 0.488 0.511
E76.0 Mucopolysaccharidosis, type I
0.000 0.488 0.511
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.488 0.511
E77.8 Other disorders of glycoprotein metabolism
0.000 0.488 0.511
E77.1 Defects in glycoprotein degradation
0.000 0.488 0.511
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.488 0.511
E24.9 Cushing's syndrome, unspecified
0.000 0.492 0.508
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.494 0.505
E84.8 Cystic fibrosis with other manifestations
0.000 0.496 0.504
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.496 0.504
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.496 0.504
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.496 0.504
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.496 0.504
E79.1 Lesch-Nyhan syndrome
0.000 0.496 0.504
M06.34 Rheumatoid nodule (Hand)
0.000 0.496 0.504
E89.3 Postprocedural hypopituitarism
0.000 0.497 0.503
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.498 0.502 0.000
E13.8 With unspecified complications
0.000 0.503 0.497
E13.7 With multiple complications
0.000 0.503 0.497
E13.6 With other specified complications
0.000 0.503 0.497
E13.5 With peripheral circulatory complications
0.000 0.503 0.497
E13.4 With neurological complications
0.000 0.503 0.497
E13.3 With ophthalmic complications
0.000 0.503 0.497
E13.2 With renal complications
0.000 0.503 0.497
E13.1 With ketoacidosis
0.000 0.503 0.497
E13.0 With coma
0.000 0.503 0.497
E84.9 Cystic fibrosis, unspecified
0.000 0.506 0.494
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.506 0.494
E23.1 Drug-induced hypopituitarism
0.000 0.506 0.494
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.507 0.493
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.510 0.490
E06.5 Other chronic thyroiditis
0.000 0.512 0.488
E06.4 Drug-induced thyroiditis
0.000 0.512 0.488
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.512 0.488
E06.1 Subacute thyroiditis
0.000 0.512 0.488
E06.0 Acute thyroiditis
0.000 0.512 0.488
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.513 0.487
E45 Retarded development following protein-energy malnutrition
0.000 0.513 0.487
E43 Unspecified severe protein-energy malnutrition
0.000 0.513 0.487
E42 Marasmic kwashiorkor
0.000 0.513 0.487
E41 Nutritional marasmus
0.000 0.513 0.487
E40 Kwashiorkor
0.000 0.513 0.487
E34 Other endocrine disorders
0.000 0.514 0.486
E75.6 Lipid storage disorder, unspecified
0.000 0.516 0.484
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.516 0.484
E75.3 Sphingolipidosis, unspecified
0.000 0.516 0.484
E75.2 Other sphingolipidosis
0.000 0.516 0.484
E75.1 Other gangliosidosis
0.000 0.516 0.484
E75.0 GM2 gangliosidosis
0.000 0.516 0.484
E61 Deficiency of other nutrient elements
0.000 0.519 0.481
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.521 0.478
E21.3 Hyperparathyroidism, unspecified
0.000 0.523 0.477
E13.9 Without complications
0.000 0.527 0.473
E11.4 With neurological complications
0.000 0.527 0.473
E06.3 Autoimmune thyroiditis
0.000 0.528 0.472
E06.9 Thyroiditis, unspecified
0.000 0.529 0.470
E73.8 Other lactose intolerance
0.000 0.532 0.468
E73.1 Secondary lactase deficiency
0.000 0.532 0.468
E73.0 Congenital lactase deficiency
0.000 0.532 0.468
E65-E68 Obesity and other hyperalimentation
0.000 0.534 0.466
E29.9 Testicular dysfunction, unspecified
0.000 0.538 0.461
E29.8 Other testicular dysfunction
0.000 0.538 0.461
E29.0 Testicular hyperfunction
0.000 0.538 0.461
E23.0 Hypopituitarism
0.000 0.541 0.459
E20 Hypoparathyroidism
0.000 0.545 0.455
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.545 0.455
E24.8 Other Cushing's syndrome
0.000 0.545 0.455
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.545 0.455
E24.3 Ectopic ACTH syndrome
0.000 0.545 0.455
E24.2 Drug-induced Cushing's syndrome
0.000 0.545 0.455
E24.1 Nelson's syndrome
0.000 0.545 0.455
E24.0 Pituitary-dependent Cushing's disease
0.000 0.545 0.455
I12.0 Hypertensive renal disease with renal failure
0.000 0.546 0.454
E28.3 Primary ovarian failure
0.000 0.547 0.453
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.547 0.453
E46 Unspecified protein-energy malnutrition
0.000 0.551 0.448
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.553 0.447
E75.5 Other lipid storage disorders
0.000 0.555 0.445
G36.9 Acute disseminated demyelination, unspecified
0.441 0.559 0.000
G36.8 Other specified acute disseminated demyelination
0.441 0.559 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.441 0.559 0.000
G36.0 Neuromyelitis optica [Devic]
0.441 0.559 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.559 0.441
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.561 0.439
M06.8 Other specified rheumatoid arthritis
0.000 0.562 0.438
M06.2 Rheumatoid bursitis
0.000 0.562 0.438
M06.1 Adult-onset Still's disease
0.000 0.562 0.438
E22.0 Acromegaly and pituitary gigantism
0.000 0.564 0.436
E61.1 Iron deficiency
0.000 0.569 0.431
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.577 0.422
E22.8 Other hyperfunction of pituitary gland
0.000 0.577 0.422
E25.9 Adrenogenital disorder, unspecified
0.000 0.583 0.417
E25.8 Other adrenogenital disorders
0.000 0.583 0.417
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.583 0.417
E30.9 Disorder of puberty, unspecified
0.000 0.583 0.417
E30.8 Other disorders of puberty
0.000 0.583 0.417
E30.1 Precocious puberty
0.000 0.583 0.417
E30.0 Delayed puberty
0.000 0.583 0.417
E31.9 Polyglandular dysfunction, unspecified
0.000 0.583 0.417
E31.8 Other polyglandular dysfunction
0.000 0.583 0.417
E31.1 Polyglandular hyperfunction
0.000 0.583 0.417
E31.0 Autoimmune polyglandular failure
0.000 0.583 0.417
E32.9 Disease of thymus, unspecified
0.000 0.583 0.417
E32.8 Other diseases of thymus
0.000 0.583 0.417
E32.1 Abscess of thymus
0.000 0.583 0.417
E32.0 Persistent hyperplasia of thymus
0.000 0.583 0.417
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.583 0.417
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.583 0.417
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.583 0.417
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.585 0.415
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.585 0.415
E89.5 Postprocedural testicular hypofunction
0.000 0.585 0.415
E89.1 Postprocedural hypoinsulinaemia
0.000 0.585 0.415
E89.4 Postprocedural ovarian failure
0.000 0.585 0.415
E26.9 Hyperaldosteronism, unspecified
0.000 0.590 0.410
E26.8 Other hyperaldosteronism
0.000 0.590 0.410
E26.1 Secondary hyperaldosteronism
0.000 0.590 0.410
E73.9 Lactose intolerance, unspecified
0.000 0.592 0.407
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.595 0.405
M06.38 Rheumatoid nodule (Other)
0.000 0.595 0.405
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.595 0.405
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.595 0.405
M06.33 Rheumatoid nodule (Forearm)
0.000 0.595 0.405
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.595 0.405
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.595 0.405
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.596 0.403
E63 Other nutritional deficiencies
0.000 0.596 0.403
E56 Other vitamin deficiencies
0.000 0.596 0.403
E51 Thiamine deficiency
0.000 0.596 0.403
E50 Vitamin A deficiency
0.000 0.596 0.403
E60 Dietary zinc deficiency
0.000 0.596 0.403
E59 Dietary selenium deficiency
0.000 0.596 0.403
E58 Dietary calcium deficiency
0.000 0.596 0.403
E54 Ascorbic acid deficiency
0.000 0.596 0.403
E52 Niacin deficiency [pellagra]
0.000 0.596 0.403
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.597 0.403
E21.4 Other specified disorders of parathyroid gland
0.000 0.597 0.403
E21.2 Other hyperparathyroidism
0.000 0.597 0.403
I15.1 Hypertension secondary to other renal disorders
0.000 0.598 0.401
M06.4 Inflammatory polyarthropathy
0.000 0.599 0.400
E83.9 Disorder of mineral metabolism, unspecified
0.214 0.600 0.186
E83.8 Other disorders of mineral metabolism
0.214 0.600 0.186
E83.2 Disorders of zinc metabolism
0.214 0.600 0.186
E83.0 Disorders of copper metabolism
0.214 0.600 0.186
E26.0 Primary hyperaldosteronism
0.000 0.600 0.400
E22.1 Hyperprolactinaemia
0.000 0.605 0.395
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.608 0.392
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.615 0.385
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.615 0.385
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.615 0.385
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.615 0.385
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.615 0.385
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.615 0.385
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.615 0.385
I15.9 Seconday hypertension, unspecified
0.000 0.616 0.384
I15.8 Other secondary hypertension
0.000 0.616 0.384
I15.2 Hypertension secondary to endocrine disorders
0.000 0.616 0.384
I15.0 Renovascular hypertension
0.000 0.616 0.384
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.627 0.373
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.629 0.371
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.629 0.371
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.629 0.371
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.629 0.371
I25 Chronic ischaemic heart disease
0.000 0.631 0.369
I20-I25 Ischaemic heart diseases
0.000 0.632 0.368
E88 Other metabolic disorders
0.000 0.632 0.367
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.637 0.362
E80.5 Crigler-Najjar syndrome
0.000 0.637 0.362
E80.3 Defects of catalase and peroxydase
0.000 0.637 0.362
E80.2 Other porphyria
0.000 0.637 0.362
E80.0 Hereditary erythropoietic porphyria
0.000 0.637 0.362
I25.1 Atherosclerotic heart disease
0.000 0.639 0.361
I22 Subsequent myocardial infarction
0.000 0.641 0.359
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.643 0.356
E80.6 Other disorders of bilirubin metabolism
0.000 0.644 0.356
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.646 0.354
E44.1 Mild protein-energy malnutrition
0.000 0.651 0.349
E44.0 Moderate protein-energy malnutrition
0.000 0.651 0.349
E34.5 Androgen resistance syndrome
0.000 0.651 0.349
E34.4 Constitutional tall stature
0.000 0.651 0.349
E34.3 Short stature, not elsewhere classified
0.000 0.651 0.349
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.651 0.349
E34.1 Other hypersecretion of intestinal hormones
0.000 0.651 0.349
E27 Other disorders of adrenal gland
0.000 0.652 0.348
E80.1 Porphyria cutanea tarda
0.000 0.653 0.347
I25.5 Ischaemic cardiomyopathy
0.000 0.654 0.346
E61.9 Deficiency of nutrient element, unspecified
0.000 0.655 0.345
E61.8 Deficiency of other specified nutrient elements
0.000 0.655 0.345
E61.7 Deficiency of multiple nutrient elements
0.000 0.655 0.345
E61.6 Vanadium deficiency
0.000 0.655 0.345
E61.5 Molybdenum deficiency
0.000 0.655 0.345
E61.4 Chromium deficiency
0.000 0.655 0.345
E61.3 Manganese deficiency
0.000 0.655 0.345
E61.0 Copper deficiency
0.000 0.655 0.345
I24 Other acute ischaemic heart diseases
0.000 0.656 0.344
E83.3 Disorders of phosphorus metabolism
0.202 0.662 0.135
E67 Other hyperalimentation
0.000 0.666 0.334
E68 Sequelae of hyperalimentation
0.000 0.666 0.334
E65 Localised adiposity
0.000 0.666 0.334
I25.2 Old myocardial infarction
0.000 0.666 0.334
M06.0 Seronegative rheumatoid arthritis
0.000 0.668 0.332
E34.8 Other specified endocrine disorders
0.000 0.671 0.328
E34.0 Carcinoid syndrome
0.000 0.673 0.326
E20.8 Other hypoparathyroidism
0.000 0.674 0.326
E20.1 Pseudohypoparathyroidism
0.000 0.674 0.326
E20.0 Idiopathic hypoparathyroidism
0.000 0.674 0.326
E61.2 Magnesium deficiency
0.000 0.679 0.320
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.684 0.316
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.686 0.314
M06.18 Adult-onset Still's disease (Other)
0.000 0.686 0.314
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.686 0.314
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.686 0.314
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.686 0.314
M06.14 Adult-onset Still's disease (Hand)
0.000 0.686 0.314
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.686 0.314
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.686 0.314
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.686 0.314
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.686 0.314
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.686 0.314
M06.28 Rheumatoid bursitis (Other)
0.000 0.686 0.314
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.686 0.314
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.686 0.314
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.686 0.314
M06.24 Rheumatoid bursitis (Hand)
0.000 0.686 0.314
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.686 0.314
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.686 0.314
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.686 0.314
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.686 0.314
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.686 0.314
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.686 0.314
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.686 0.314
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.686 0.314
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.686 0.314
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.686 0.314
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.686 0.314
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.686 0.314
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.686 0.314
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.686 0.314
E34.9 Endocrine disorder, unspecified
0.000 0.688 0.311
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.693 0.307
E27.9 Disorder of adrenal gland, unspecified
0.000 0.695 0.305
I23 Certain current complications following acute myocardial infarction
0.000 0.695 0.305
E21.0 Primary hyperparathyroidism
0.000 0.695 0.305
E55 Vitamin D deficiency
0.000 0.708 0.292
E50.9 Vitamin A deficiency, unspecified
0.000 0.710 0.289
E50.8 Other manifestations of vitamin A deficiency
0.000 0.710 0.289
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.710 0.289
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.710 0.289
E50.5 Vitamin A deficiency with night blindness
0.000 0.710 0.289
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.710 0.289
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.710 0.289
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.710 0.289
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.710 0.289
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.710 0.289
E51.9 Thiamine deficiency, unspecified
0.000 0.710 0.289
E51.8 Other manifestations of thiamine deficiency
0.000 0.710 0.289
E51.2 Wernicke's encephalopathy
0.000 0.710 0.289
E51.1 Beriberi
0.000 0.710 0.289
E56.9 Vitamin deficiency, unspecified
0.000 0.710 0.289
E56.8 Deficiency of other vitamins
0.000 0.710 0.289
E56.1 Deficiency of vitamin K
0.000 0.710 0.289
E56.0 Deficiency of vitamin E
0.000 0.710 0.289
E63.9 Nutritional deficiency, unspecified
0.000 0.710 0.289
E63.8 Other specified nutritional deficiencies
0.000 0.710 0.289
E63.1 Imbalance of constituents of food intake
0.000 0.710 0.289
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.710 0.289
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.710 0.289
E64.8 Sequelae of other nutritional deficiencies
0.000 0.710 0.289
E64.3 Sequelae of rickets
0.000 0.710 0.289
E64.2 Sequelae of vitamin C deficiency
0.000 0.710 0.289
E64.1 Sequelae of vitamin A deficiency
0.000 0.710 0.289
E64.0 Sequelae of protein-energy malnutrition
0.000 0.710 0.289
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.713 0.287
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.713 0.287
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.713 0.287
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.713 0.287
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.713 0.287
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.713 0.287
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.713 0.287

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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