TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs2516393
log Bayes Factor = 66.5037
Chromosome 6   position 31,506,744  (GRCh37) Explore rs2516393 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
I20.9 Angina pectoris, unspecified
0.000 0.008 0.992
E14.3 With ophthalmic complications
0.000 0.010 0.990
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.011 0.989
I25.5 Ischaemic cardiomyopathy
0.000 0.013 0.987
E10.1 With ketoacidosis
0.000 0.014 0.986
E14.9 Without complications
0.000 0.015 0.985
E10.4 With neurological complications
0.000 0.018 0.982
I22 Subsequent myocardial infarction
0.000 0.021 0.979
I20.0 Unstable angina
0.000 0.021 0.979
G35-G37 Demyelinating diseases of the central nervous system
0.965 0.035 0.000
I21 Acute myocardial infarction
0.000 0.037 0.963
G37 Other demyelinating diseases of central nervous system
0.958 0.042 0.000
I25.2 Old myocardial infarction
0.000 0.044 0.956
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.049 0.951
E83.1 Disorders of iron metabolism
0.947 0.053 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.060 0.940
I10 Essential (primary) hypertension
0.000 0.061 0.939
G37.9 Demyelinating disease of central nervous system, unspecified
0.939 0.061 0.000
E70-E90 Metabolic disorders
0.000 0.067 0.933
E13 Other specified diabetes mellitus
0.000 0.073 0.927
I21.9 Acute myocardial infarction, unspecified
0.000 0.080 0.920
I24 Other acute ischaemic heart diseases
0.000 0.080 0.920
E78.8 Other disorders of lipoprotein metabolism
0.000 0.086 0.914
R07.4 Chest pain, unspecified
0.000 0.094 0.906
E11.2 With renal complications
0.000 0.113 0.887
E10.2 With renal complications
0.000 0.119 0.880
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.124 0.876
E13.9 Without complications
0.000 0.125 0.875
L40-L45 Papulosquamous disorders
0.000 0.129 0.871
E78.2 Mixed hyperlipidaemia
0.000 0.131 0.869
E11.0 With coma
0.000 0.136 0.864
I10-I15 Hypertensive diseases
0.000 0.137 0.863
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.151 0.849
I21.4 Acute subendocardial myocardial infarction
0.000 0.153 0.847
L43 Lichen planus
0.000 0.156 0.844
I25.3 Aneurysm of heart
0.000 0.157 0.843
G37.8 Other specified demyelinating diseases of central nervous system
0.841 0.159 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.159 0.841
L40.8 Other psoriasis
0.000 0.160 0.840
E11.1 With ketoacidosis
0.000 0.168 0.832
E00-E07 Disorders of thyroid gland
0.000 0.176 0.824
E14.4 With neurological complications
0.000 0.177 0.823
E10.8 With unspecified complications
0.000 0.181 0.819
E10.5 With peripheral circulatory complications
0.000 0.182 0.818
E78.5 Hyperlipidaemia, unspecified
0.000 0.183 0.817
I24.8 Other forms of acute ischaemic heart disease
0.000 0.190 0.810
L43.9 Lichen planus, unspecified
0.000 0.191 0.809
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.200 0.800
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.203 0.797
E10.0 With coma
0.000 0.208 0.792
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.782 0.217 0.000
E03 Other hypothyroidism
0.000 0.225 0.775
I23 Certain current complications following acute myocardial infarction
0.000 0.225 0.774
L40.0 Psoriasis vulgaris
0.000 0.226 0.774
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.227 0.773
E16 Other disorders of pancreatic internal secretion
0.000 0.230 0.770
E85 Amyloidosis
0.000 0.233 0.767
E11.6 With other specified complications
0.000 0.233 0.767
E03.9 Hypothyroidism, unspecified
0.000 0.241 0.759
I15 Secondary hypertension
0.000 0.243 0.757
E78.6 Lipoprotein deficiency
0.000 0.250 0.750
I12 Hypertensive renal disease
0.000 0.254 0.746
E05.9 Thyrotoxicosis, unspecified
0.000 0.258 0.742
E14.5 With peripheral circulatory complications
0.000 0.267 0.733
E10.6 With other specified complications
0.000 0.267 0.733
E74 Other disorders of carbohydrate metabolism
0.000 0.273 0.727
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.275 0.725
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.278 0.722
E14.6 With other specified complications
0.000 0.279 0.721
E78.1 Pure hyperglyceridaemia
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L43.8 Other lichen planus
0.000 0.285 0.715
E78.3 Hyperchylomicronaemia
0.000 0.291 0.709
E16.2 Hypoglycaemia, unspecified
0.000 0.295 0.705
G36 Other acute disseminated demyelination
0.696 0.304 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.306 0.694
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.310 0.690
E11.5 With peripheral circulatory complications
0.000 0.311 0.689
G37.5 Concentric sclerosis [Balo]
0.687 0.313 0.000
G37.4 Subacute necrotising myelitis
0.687 0.313 0.000
G37.2 Central pontine myelinolysis
0.687 0.313 0.000
G37.1 Central demyelination of corpus callosum
0.687 0.313 0.000
G37.0 Diffuse sclerosis
0.687 0.313 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.314 0.685
I12.9 Hypertensive renal disease without renal failure
0.000 0.326 0.674
E79 Disorders of purine and pyrimidine metabolism
0.000 0.330 0.669
E77 Disorders of glycoprotein metabolism
0.000 0.331 0.669
E76 Disorders of glycosaminoglycan metabolism
0.000 0.331 0.669
E72 Other disorders of amino-acid metabolism
0.000 0.331 0.669
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.331 0.669
E70 Disorders of aromatic amino-acid metabolism
0.000 0.331 0.669
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.331 0.669
E13.8 With unspecified complications
0.000 0.335 0.665
E13.7 With multiple complications
0.000 0.335 0.665
E13.6 With other specified complications
0.000 0.335 0.665
E13.5 With peripheral circulatory complications
0.000 0.335 0.665
E13.4 With neurological complications
0.000 0.335 0.665
E13.3 With ophthalmic complications
0.000 0.335 0.665
E13.2 With renal complications
0.000 0.335 0.665
E13.1 With ketoacidosis
0.000 0.335 0.665
E13.0 With coma
0.000 0.335 0.665
I11 Hypertensive heart disease
0.000 0.336 0.664
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.340 0.660
E78.4 Other hyperlipidaemia
0.000 0.341 0.658
I22.8 Subsequent myocardial infarction of other sites
0.000 0.345 0.655
E85.9 Amyloidosis, unspecified
0.000 0.351 0.649
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.353 0.647
L42 Pityriasis rosea
0.000 0.369 0.631
L44 Other papulosquamous disorders
0.000 0.375 0.625
L41 Parapsoriasis
0.000 0.375 0.625
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.375 0.625
I13 Hypertensive heart and renal disease
0.000 0.381 0.619
I23.8 Other current complications following acute myocardial infarction
0.000 0.387 0.613
E84 Cystic fibrosis
0.000 0.387 0.612
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.387 0.612
I20.1 Angina pectoris with documented spasm
0.000 0.390 0.610
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.392 0.608
L43.3 Subacute (active) lichen planus
0.000 0.395 0.605
L43.2 Lichenoid drug reaction
0.000 0.395 0.605
L43.1 Bullous lichen planus
0.000 0.395 0.605
L43.0 Hypertrophic lichen planus
0.000 0.395 0.605
E16.1 Other hypoglycaemia
0.000 0.395 0.605
E15 Nondiabetic hypoglycaemic coma
0.000 0.397 0.603
E11.4 With neurological complications
0.000 0.401 0.599
E40-E46 Malnutrition
0.000 0.408 0.592
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.409 0.591
E00 Congenital iodine-deficiency syndrome
0.000 0.409 0.591
I25.4 Coronary artery aneurysm
0.000 0.420 0.580
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.421 0.579
E11.3 With ophthalmic complications
0.000 0.427 0.573
E85.4 Organ-limited amyloidosis
0.000 0.441 0.559
E03.5 Myxoedema coma
0.000 0.444 0.556
E03.4 Atrophy of thyroid (acquired)
0.000 0.444 0.556
E03.3 Postinfectious hypothyroidism
0.000 0.444 0.556
E03.1 Congenital hypothyroidism without goitre
0.000 0.444 0.556
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.444 0.556
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.445 0.555
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.445 0.555
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.445 0.555
E05.5 Thyroid crisis or storm
0.000 0.446 0.554
E05.4 Thyrotoxicosis factitia
0.000 0.446 0.554
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.446 0.554
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.446 0.554
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.448 0.552
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.448 0.552
E16.4 Abnormal secretion of gastrin
0.000 0.448 0.552
E16.3 Increased secretion of glucagon
0.000 0.448 0.552
E85.8 Other amyloidosis
0.000 0.450 0.550
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.450 0.550
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.450 0.550
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.450 0.550
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.453 0.547
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.455 0.545
E73 Lactose intolerance
0.000 0.456 0.543
I15.8 Other secondary hypertension
0.000 0.457 0.543
I15.2 Hypertension secondary to endocrine disorders
0.000 0.457 0.543
I15.0 Renovascular hypertension
0.000 0.457 0.543
Chapter IX Diseases of the circulatory system
0.000 0.459 0.541
E85.3 Secondary systemic amyloidosis
0.000 0.462 0.538
I15.9 Seconday hypertension, unspecified
0.000 0.468 0.532
E07 Other disorders of thyroid
0.000 0.469 0.531
E89.3 Postprocedural hypopituitarism
0.000 0.472 0.528
I24.1 Dressler's syndrome
0.000 0.476 0.524
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.478 0.522
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.479 0.521
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.479 0.521
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.479 0.521
E74.2 Disorders of galactose metabolism
0.000 0.479 0.521
E74.1 Disorders of fructose metabolism
0.000 0.479 0.521
E74.0 Glycogen storage disease
0.000 0.479 0.521
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.491 0.509
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.492 0.508
G36.0 Neuromyelitis optica [Devic]
0.503 0.497 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.498 0.502
E11.8 With unspecified complications
0.000 0.501 0.499
G36.9 Acute disseminated demyelination, unspecified
0.499 0.501 0.000
G36.8 Other specified acute disseminated demyelination
0.499 0.501 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.499 0.501 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.501 0.498
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.503 0.497
E05.8 Other thyrotoxicosis
0.000 0.508 0.492
E83 Disorders of mineral metabolism
0.352 0.516 0.132
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.519 0.480
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.520 0.480
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.520 0.480
E79.1 Lesch-Nyhan syndrome
0.000 0.520 0.480
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.520 0.480
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.520 0.480
E70.3 Albinism
0.000 0.520 0.480
E70.2 Disorders of tyrosine metabolism
0.000 0.520 0.480
E70.1 Other hyperphenylalaninaemias
0.000 0.520 0.480
E70.0 Classical phenylketonuria
0.000 0.520 0.480
E71.3 Disorders of fatty-acid metabolism
0.000 0.520 0.480
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.520 0.480
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.520 0.480
E71.0 Maple-syrup-urine disease
0.000 0.520 0.480
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.520 0.480
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.520 0.480
E72.5 Disorders of glycine metabolism
0.000 0.520 0.480
E72.4 Disorders of ornithine metabolism
0.000 0.520 0.480
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.520 0.480
E72.2 Disorders of urea cycle metabolism
0.000 0.520 0.480
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.520 0.480
E72.0 Disorders of amino-acid transport
0.000 0.520 0.480
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.520 0.480
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.520 0.480
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.520 0.480
E76.2 Other mucopolysaccharidoses
0.000 0.520 0.480
E76.1 Mucopolysaccharidosis, type II
0.000 0.520 0.480
E76.0 Mucopolysaccharidosis, type I
0.000 0.520 0.480
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.520 0.480
E77.8 Other disorders of glycoprotein metabolism
0.000 0.520 0.480
E77.1 Defects in glycoprotein degradation
0.000 0.520 0.480
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.520 0.480
E06 Thyroiditis
0.000 0.521 0.479
E75.6 Lipid storage disorder, unspecified
0.000 0.527 0.473
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.527 0.473
E75.3 Sphingolipidosis, unspecified
0.000 0.527 0.473
E75.2 Other sphingolipidosis
0.000 0.527 0.473
E75.1 Other gangliosidosis
0.000 0.527 0.473
E75.0 GM2 gangliosidosis
0.000 0.527 0.473
E75.5 Other lipid storage disorders
0.000 0.536 0.464
E88 Other metabolic disorders
0.000 0.540 0.459
L41.9 Parapsoriasis, unspecified
0.000 0.552 0.448
L41.8 Other parapsoriasis
0.000 0.552 0.448
L41.5 Retiform parapsoriasis
0.000 0.552 0.448
L41.4 Large plaque parapsoriasis
0.000 0.552 0.448
L41.3 Small plaque parapsoriasis
0.000 0.552 0.448
L41.2 Lymphomatoid papulosis
0.000 0.552 0.448
L41.1 Pityriasis lichenoides chronica
0.000 0.552 0.448
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.552 0.448
L44.9 Papulosquamous disorder, unspecified
0.000 0.552 0.448
L44.8 Other specified papulosquamous disorders
0.000 0.552 0.448
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.552 0.448
L44.3 Lichen ruber moniliformis
0.000 0.552 0.448
L44.2 Lichen striatus
0.000 0.552 0.448
L44.1 Lichen nitidus
0.000 0.552 0.448
L44.0 Pityriasis rubra pilaris
0.000 0.552 0.448
E65-E68 Obesity and other hyperalimentation
0.000 0.553 0.447
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.556 0.444
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.556 0.444
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.556 0.444
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.556 0.444
E84.8 Cystic fibrosis with other manifestations
0.000 0.561 0.439
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.561 0.439
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.561 0.439
E50-E64 Other nutritional deficiencies
0.000 0.562 0.438
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.564 0.436
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.564 0.436
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.564 0.436
E89.5 Postprocedural testicular hypofunction
0.000 0.564 0.436
E89.1 Postprocedural hypoinsulinaemia
0.000 0.564 0.436
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.575 0.425
E45 Retarded development following protein-energy malnutrition
0.000 0.575 0.425
E43 Unspecified severe protein-energy malnutrition
0.000 0.575 0.425
E42 Marasmic kwashiorkor
0.000 0.575 0.425
E41 Nutritional marasmus
0.000 0.575 0.425
E40 Kwashiorkor
0.000 0.575 0.425
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.576 0.424
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.576 0.424
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.576 0.424
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.576 0.424
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.576 0.424
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.576 0.424
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.576 0.424
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.576 0.424
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.583 0.417
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.587 0.413
E89.4 Postprocedural ovarian failure
0.000 0.591 0.409
E73.8 Other lactose intolerance
0.000 0.610 0.390
E73.1 Secondary lactase deficiency
0.000 0.610 0.390
E73.0 Congenital lactase deficiency
0.000 0.610 0.390
I00-I02 Acute rheumatic fever
0.000 0.612 0.388
E89.2 Postprocedural hypoparathyroidism
0.000 0.617 0.383
E84.9 Cystic fibrosis, unspecified
0.001 0.617 0.382
K90 Intestinal malabsorption
0.000 0.618 0.382
E07.1 Dyshormogenetic goitre
0.000 0.619 0.381
E07.0 Hypersecretion of calcitonin
0.000 0.619 0.381
E07.8 Other specified disorders of thyroid
0.000 0.622 0.378
E80.6 Other disorders of bilirubin metabolism
0.000 0.626 0.374
E88.2 Lipomatosis, not elsewhere classified
0.000 0.635 0.365
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.642 0.357
E80.5 Crigler-Najjar syndrome
0.000 0.642 0.357
E80.3 Defects of catalase and peroxydase
0.000 0.642 0.357
E80.2 Other porphyria
0.000 0.642 0.357
E80.1 Porphyria cutanea tarda
0.000 0.642 0.357
E80.0 Hereditary erythropoietic porphyria
0.000 0.642 0.357
E83.9 Disorder of mineral metabolism, unspecified
0.252 0.653 0.095
E83.8 Other disorders of mineral metabolism
0.252 0.653 0.095
E83.2 Disorders of zinc metabolism
0.252 0.653 0.095
E83.0 Disorders of copper metabolism
0.252 0.653 0.095
E06.5 Other chronic thyroiditis
0.000 0.656 0.344
E06.4 Drug-induced thyroiditis
0.000 0.656 0.344
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.656 0.344
E06.1 Subacute thyroiditis
0.000 0.656 0.344
E06.0 Acute thyroiditis
0.000 0.656 0.344
E46 Unspecified protein-energy malnutrition
0.000 0.657 0.343
E83.3 Disorders of phosphorus metabolism
0.296 0.659 0.045
E61 Deficiency of other nutrient elements
0.000 0.660 0.340
E88.8 Other specified metabolic disorders
0.000 0.669 0.331
E88.9 Metabolic disorder, unspecified
0.000 0.670 0.329
E03.8 Other specified hypothyroidism
0.001 0.672 0.327
E88.3 Tumour lysis syndrome
0.000 0.674 0.326
E07.9 Disorder of thyroid, unspecified
0.000 0.674 0.326
E06.9 Thyroiditis, unspecified
0.000 0.675 0.325
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.679 0.321
E67 Other hyperalimentation
0.000 0.679 0.321
E68 Sequelae of hyperalimentation
0.000 0.679 0.321
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.686 0.314
E63 Other nutritional deficiencies
0.000 0.686 0.314
E56 Other vitamin deficiencies
0.000 0.686 0.314
E51 Thiamine deficiency
0.000 0.686 0.314
E50 Vitamin A deficiency
0.000 0.686 0.314
E60 Dietary zinc deficiency
0.000 0.686 0.314
E59 Dietary selenium deficiency
0.000 0.686 0.314
E58 Dietary calcium deficiency
0.000 0.686 0.314
E54 Ascorbic acid deficiency
0.000 0.686 0.314
E52 Niacin deficiency [pellagra]
0.000 0.686 0.314
E65 Localised adiposity
0.000 0.689 0.311
E44.1 Mild protein-energy malnutrition
0.000 0.695 0.304
E44.0 Moderate protein-energy malnutrition
0.000 0.695 0.304
E20-E35 Disorders of other endocrine glands
0.000 0.696 0.304
I02 Rheumatic chorea
0.000 0.721 0.278
I01 Rheumatic fever with heart involvement
0.000 0.721 0.278
I00 Rheumatic fever without mention of heart involvement
0.000 0.721 0.278
E61.1 Iron deficiency
0.000 0.723 0.277
E89.0 Postprocedural hypothyroidism
0.000 0.724 0.276
K90.3 Pancreatic steatorrhoea
0.000 0.726 0.274
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.726 0.274
K90.1 Tropical sprue
0.000 0.726 0.274
K90.8 Other intestinal malabsorption
0.000 0.727 0.273
K90.9 Intestinal malabsorption, unspecified
0.000 0.727 0.273
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.734 0.265
E73.9 Lactose intolerance, unspecified
0.001 0.735 0.264
E06.3 Autoimmune thyroiditis
0.000 0.738 0.262
E23 Hypofunction and other disorders of pituitary gland
0.000 0.744 0.256
E55 Vitamin D deficiency
0.000 0.753 0.247
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.755 0.244
E61.9 Deficiency of nutrient element, unspecified
0.000 0.756 0.244
E61.8 Deficiency of other specified nutrient elements
0.000 0.756 0.244
E61.7 Deficiency of multiple nutrient elements
0.000 0.756 0.244
E61.6 Vanadium deficiency
0.000 0.756 0.244
E61.5 Molybdenum deficiency
0.000 0.756 0.244
E61.4 Chromium deficiency
0.000 0.756 0.244
E61.3 Manganese deficiency
0.000 0.756 0.244
E61.0 Copper deficiency
0.000 0.756 0.244
E22 Hyperfunction of pituitary gland
0.000 0.759 0.241
E61.2 Magnesium deficiency
0.000 0.767 0.233
E67.8 Other specified hyperalimentation
0.000 0.770 0.230
E67.3 Hypervitaminosis D
0.000 0.770 0.230
E67.2 Megavitamin-B6 syndrome
0.000 0.770 0.230
E67.1 Hypercarotenaemia
0.000 0.770 0.230
E67.0 Hypervitaminosis A
0.000 0.770 0.230
E50.9 Vitamin A deficiency, unspecified
0.000 0.775 0.225
E50.8 Other manifestations of vitamin A deficiency
0.000 0.775 0.225
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.775 0.225
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.775 0.225
E50.5 Vitamin A deficiency with night blindness
0.000 0.775 0.225
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.775 0.225
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.775 0.225
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.775 0.225
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.775 0.225
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.775 0.225
E51.9 Thiamine deficiency, unspecified
0.000 0.775 0.225
E51.8 Other manifestations of thiamine deficiency
0.000 0.775 0.225
E51.2 Wernicke's encephalopathy
0.000 0.775 0.225
E51.1 Beriberi
0.000 0.775 0.225
E56.9 Vitamin deficiency, unspecified
0.000 0.775 0.225
E56.8 Deficiency of other vitamins
0.000 0.775 0.225
E56.1 Deficiency of vitamin K
0.000 0.775 0.225
E56.0 Deficiency of vitamin E
0.000 0.775 0.225
E63.9 Nutritional deficiency, unspecified
0.000 0.775 0.225
E63.8 Other specified nutritional deficiencies
0.000 0.775 0.225
E63.1 Imbalance of constituents of food intake
0.000 0.775 0.225
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.775 0.225
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.775 0.225
E64.8 Sequelae of other nutritional deficiencies
0.000 0.775 0.225
E64.3 Sequelae of rickets
0.000 0.775 0.225
E64.2 Sequelae of vitamin C deficiency
0.000 0.775 0.225
E64.1 Sequelae of vitamin A deficiency
0.000 0.775 0.225
E64.0 Sequelae of protein-energy malnutrition
0.000 0.775 0.225
E26 Hyperaldosteronism
0.000 0.777 0.223
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.782 0.218
E32 Diseases of thymus
0.000 0.782 0.218
E31 Polyglandular dysfunction
0.000 0.782 0.218
E30 Disorders of puberty, not elsewhere classified
0.000 0.782 0.218
E25 Adrenogenital disorders
0.000 0.782 0.218
E23.6 Other disorders of pituitary gland
0.000 0.785 0.215
E23.2 Diabetes insipidus
0.000 0.791 0.209
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.795 0.205
E29 Testicular dysfunction
0.000 0.797 0.203
E83.4 Disorders of magnesium metabolism
0.118 0.797 0.085
E24 Cushing's syndrome
0.000 0.797 0.203
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.800 0.200
I01.8 Other acute rheumatic heart disease
0.000 0.800 0.200
I01.2 Acute rheumatic myocarditis
0.000 0.800 0.200
I01.1 Acute rheumatic endocarditis
0.000 0.800 0.200
I01.0 Acute rheumatic pericarditis
0.000 0.800 0.200
I02.9 Rheumatic chorea without heart involvement
0.000 0.800 0.200
I02.0 Rheumatic chorea with heart involvement
0.000 0.800 0.200
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.800 0.198
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.802 0.198
E20 Hypoparathyroidism
0.000 0.805 0.195
E23.7 Disorder of pituitary gland, unspecified
0.000 0.806 0.194
E28 Ovarian dysfunction
0.000 0.813 0.187
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.816 0.183
E23.1 Drug-induced hypopituitarism
0.000 0.816 0.183
E55.0 Rickets, active
0.000 0.823 0.177
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.827 0.173
E22.8 Other hyperfunction of pituitary gland
0.000 0.827 0.173
E22.1 Hyperprolactinaemia
0.000 0.827 0.173
E26.0 Primary hyperaldosteronism
0.000 0.835 0.165
E26.9 Hyperaldosteronism, unspecified
0.000 0.840 0.160
E26.8 Other hyperaldosteronism
0.000 0.840 0.160
E26.1 Secondary hyperaldosteronism
0.000 0.840 0.160
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.842 0.158
E34 Other endocrine disorders
0.000 0.843 0.156
E25.9 Adrenogenital disorder, unspecified
0.000 0.844 0.156
E25.8 Other adrenogenital disorders
0.000 0.844 0.156
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.844 0.156
E30.9 Disorder of puberty, unspecified
0.000 0.844 0.156
E30.8 Other disorders of puberty
0.000 0.844 0.156
E30.1 Precocious puberty
0.000 0.844 0.156
E30.0 Delayed puberty
0.000 0.844 0.156
E31.9 Polyglandular dysfunction, unspecified
0.000 0.844 0.156
E31.8 Other polyglandular dysfunction
0.000 0.844 0.156
E31.1 Polyglandular hyperfunction
0.000 0.844 0.156
E31.0 Autoimmune polyglandular failure
0.000 0.844 0.156
E32.9 Disease of thymus, unspecified
0.000 0.844 0.156
E32.8 Other diseases of thymus
0.000 0.844 0.156
E32.1 Abscess of thymus
0.000 0.844 0.156
E32.0 Persistent hyperplasia of thymus
0.000 0.844 0.156
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.844 0.156
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.844 0.156
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.844 0.156
E22.0 Acromegaly and pituitary gigantism
0.000 0.844 0.156
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.847 0.152
E21.3 Hyperparathyroidism, unspecified
0.000 0.850 0.150
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.850 0.150
E23.0 Hypopituitarism
0.000 0.853 0.147
E29.9 Testicular dysfunction, unspecified
0.000 0.854 0.146
E29.8 Other testicular dysfunction
0.000 0.854 0.146
E29.0 Testicular hyperfunction
0.000 0.854 0.146
E80.4 Gilbert's syndrome
0.001 0.854 0.145
E24.8 Other Cushing's syndrome
0.000 0.854 0.145
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.854 0.145
E24.3 Ectopic ACTH syndrome
0.000 0.854 0.145
E24.2 Drug-induced Cushing's syndrome
0.000 0.854 0.145
E24.1 Nelson's syndrome
0.000 0.854 0.145
E24.0 Pituitary-dependent Cushing's disease
0.000 0.854 0.145
E83.5 Disorders of calcium metabolism
0.117 0.856 0.028
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.858 0.142
E21.4 Other specified disorders of parathyroid gland
0.000 0.858 0.142
E21.2 Other hyperparathyroidism
0.000 0.858 0.142
E53 Deficiency of other B group vitamins
0.001 0.858 0.141
I28 Other diseases of pulmonary vessels
0.001 0.859 0.140

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.