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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517618
log Bayes Factor = 242.769
Chromosome 6   position 30,158,127  (GRCh37) Explore rs2517618 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
K75.4 Autoimmune hepatitis
0.999 0.001 0.000
I73 Other peripheral vascular diseases
0.999 0.001 0.000
H36 Retinal disorders in diseases classified elsewhere
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
D64 Other anaemias
0.999 0.001 0.000
H36.0 Diabetic retinopathy
0.999 0.001 0.000
D64.9 Anaemia, unspecified
0.999 0.001 0.000
I73.9 Peripheral vascular disease, unspecified
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.998 0.002 0.000
E16 Other disorders of pancreatic internal secretion
0.998 0.002 0.000
J45.9 Asthma, unspecified
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
I74 Arterial embolism and thrombosis
0.997 0.003 0.000
J44 Other chronic obstructive pulmonary disease
0.997 0.003 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.997 0.003 0.000
J45 Asthma
0.997 0.003 0.000
E20-E35 Disorders of other endocrine glands
0.997 0.003 0.000
C18 Malignant neoplasm of colon
0.997 0.003 0.000
E16.2 Hypoglycaemia, unspecified
0.997 0.003 0.000
E14 Unspecified diabetes mellitus
0.997 0.003 0.000
C25 Malignant neoplasm of pancreas
0.995 0.005 0.000
K72 Hepatic failure, not elsewhere classified
0.995 0.005 0.000
D86 Sarcoidosis
0.994 0.006 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.994 0.006 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.994 0.006 0.000
E27 Other disorders of adrenal gland
0.993 0.007 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.993 0.007 0.000
E27.1 Primary adrenocortical insufficiency
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.992 0.008 0.000
D86.9 Sarcoidosis, unspecified
0.992 0.008 0.000
D61 Other aplastic anaemias
0.992 0.008 0.000
L50-L54 Urticaria and erythema
0.991 0.009 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.991 0.009 0.000
E14.3 With ophthalmic complications
0.991 0.009 0.000
H43-H45 Disorders of vitreous body and globe
0.990 0.010 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.990 0.010 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.989 0.011 0.000
E83.1 Disorders of iron metabolism
0.000 0.014 0.986
E10.1 With ketoacidosis
0.986 0.014 0.000
D61.9 Aplastic anaemia, unspecified
0.986 0.014 0.000
C18.4 Transverse colon
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
C25.9 Pancreas, unspecified
0.983 0.017 0.000
B35-B49 Mycoses
0.979 0.021 0.000
M35.3 Polymyalgia rheumatica
0.979 0.021 0.000
I77 Other disorders of arteries and arterioles
0.976 0.024 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.975 0.025 0.000
H43 Disorders of vitreous body
0.974 0.026 0.000
E10.2 With renal complications
0.974 0.026 0.000
E11.5 With peripheral circulatory complications
0.973 0.027 0.000
H34 Retinal vascular occlusions
0.970 0.030 0.000
B37 Candidiasis
0.970 0.030 0.000
M86-M90 Other osteopathies
0.966 0.034 0.000
H43.1 Vitreous haemorrhage
0.964 0.036 0.000
Chapter IX Diseases of the circulatory system
0.963 0.037 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.961 0.039 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.960 0.040 0.000
K73 Chronic hepatitis, not elsewhere classified
0.960 0.040 0.000
K72.0 Acute and subacute hepatic failure
0.959 0.041 0.000
K72.9 Hepatic failure, unspecified
0.958 0.042 0.000
I77.1 Stricture of artery
0.956 0.044 0.000
Chapter XX External causes of morbidity and mortality
0.953 0.047 0.000
C91 Lymphoid leukaemia
0.952 0.048 0.000
K75.8 Other specified inflammatory liver diseases
0.947 0.053 0.000
M86 Osteomyelitis
0.946 0.054 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.944 0.056 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.944 0.056 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.942 0.058 0.000
Chapter VI Diseases of the nervous system
0.941 0.059 0.000
C34 Malignant neoplasm of bronchus and lung
0.941 0.059 0.000
L52 Erythema nodosum
0.940 0.060 0.000
M20.1 Hallux valgus (acquired)
0.000 0.066 0.934
L50 Urticaria
0.933 0.067 0.000
B37.8 Candidiasis of other sites
0.928 0.072 0.000
C34.3 Lower lobe, bronchus or lung
0.918 0.082 0.000
M15-M19 Arthrosis
0.918 0.082 0.000
M86.9 Osteomyelitis, unspecified
0.917 0.083 0.000
K74 Fibrosis and cirrhosis of liver
0.916 0.084 0.000
E70-E90 Metabolic disorders
0.915 0.085 0.000
M34 Systemic sclerosis
0.913 0.087 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.912 0.088 0.000
C04 Malignant neoplasm of floor of mouth
0.910 0.090 0.000
L20-L30 Dermatitis and eczema
0.908 0.092 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.907 0.093 0.000
H34.8 Other retinal vascular occlusions
0.907 0.093 0.000
N40 Hyperplasia of prostate
0.000 0.093 0.907
B44 Aspergillosis
0.906 0.094 0.000
E10.4 With neurological complications
0.905 0.095 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.904 0.096 0.000
K90.9 Intestinal malabsorption, unspecified
0.904 0.096 0.000
B37.9 Candidiasis, unspecified
0.902 0.098 0.000
J46 Status asthmaticus
0.900 0.100 0.000
C25.3 Pancreatic duct
0.899 0.101 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.898 0.102 0.000
L94 Other localised connective tissue disorders
0.897 0.103 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.897 0.103 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.895 0.105 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.895 0.105 0.000
M17 Gonarthrosis [arthrosis of knee]
0.895 0.105 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.893 0.107 0.000
M20 Acquired deformities of fingers and toes
0.001 0.107 0.892
M31 Other necrotising vasculopathies
0.890 0.110 0.000
E11.9 Without complications
0.889 0.111 0.000
G30-G32 Other degenerative diseases of the nervous system
0.888 0.112 0.000
V20-V29 Motorcycle rider injured in transport accident
0.887 0.113 0.000
E50-E64 Other nutritional deficiencies
0.887 0.113 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.113 0.887
M65-M68 Disorders of synovium and tendon
0.883 0.117 0.000
M60-M63 Disorders of muscles
0.881 0.119 0.000
K73.9 Chronic hepatitis, unspecified
0.881 0.119 0.000
L53 Other erythematous conditions
0.880 0.120 0.000
M70-M79 Other soft tissue disorders
0.879 0.121 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.878 0.122 0.000
M17.1 Other primary gonarthrosis
0.878 0.122 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.875 0.125 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.875 0.125 0.000
B37.0 Candidal stomatitis
0.874 0.126 0.000
M00-M03 Infectious arthropathies
0.873 0.127 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.871 0.129 0.000
G56 Mononeuropathies of upper limb
0.870 0.130 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.869 0.131 0.000
C01 Malignant neoplasm of base of tongue
0.869 0.131 0.000
C18.9 Colon, unspecified
0.867 0.133 0.000
B02 Zoster [herpes zoster]
0.865 0.135 0.000
C91.1 Chronic lymphocytic leukaemia
0.863 0.137 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.863 0.137 0.000
H44 Disorders of globe
0.863 0.137 0.000
G56.0 Carpal tunnel syndrome
0.863 0.137 0.000
M72 Fibroblastic disorders
0.862 0.138 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.862 0.138 0.000
C85.1 B-cell lymphoma, unspecified
0.861 0.139 0.000
L30 Other dermatitis
0.861 0.139 0.000
W20-W49 Exposure to inanimate mechanical forces
0.859 0.141 0.000
W00-W19 Falls
0.858 0.142 0.000
E89.0 Postprocedural hypothyroidism
0.858 0.142 0.000
C81 Hodgkin's disease
0.856 0.144 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.856 0.144 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.856 0.144 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.855 0.145 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.855 0.145 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.854 0.146 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.853 0.147 0.000
E11.3 With ophthalmic complications
0.853 0.147 0.000
L10-L14 Bullous disorders
0.853 0.147 0.000
M18 Arthrosis of first carpometacarpal joint
0.851 0.149 0.000
C34.0 Main bronchus
0.851 0.149 0.000
M67 Other disorders of synovium and tendon
0.851 0.149 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.850 0.150 0.000
C02.9 Tongue, unspecified
0.849 0.151 0.000
C18.6 Descending colon
0.848 0.152 0.000
I74.5 Embolism and thrombosis of iliac artery
0.847 0.153 0.000
C18.0 Caecum
0.846 0.154 0.000
J90-J94 Other diseases of pleura
0.844 0.156 0.000
K74.6 Other and unspecified cirrhosis of liver
0.844 0.156 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.844 0.156 0.000
E24 Cushing's syndrome
0.844 0.156 0.000
G35 Multiple sclerosis
0.843 0.157 0.000
E23 Hypofunction and other disorders of pituitary gland
0.843 0.157 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.843 0.157 0.000
G51 Facial nerve disorders
0.843 0.157 0.000
X20-X29 Contact with venomous animals and plants
0.842 0.158 0.000
W19 Unspecified fall
0.840 0.160 0.000
I73.0 Raynaud's syndrome
0.837 0.163 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.836 0.164 0.000
H34.2 Other retinal artery occlusions
0.836 0.164 0.000
D70 Agranulocytosis
0.834 0.166 0.000
B25-B34 Other viral diseases
0.834 0.166 0.000
J41 Simple and mucopurulent chronic bronchitis
0.833 0.167 0.000
C83.3 Large cell (diffuse)
0.832 0.168 0.000
M89 Other disorders of bone
0.830 0.170 0.000
D80 Immunodeficiency with predominantly antibody defects
0.830 0.170 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.829 0.171 0.000
L50.9 Urticaria, unspecified
0.829 0.171 0.000
M67.8 Other specified disorders of synovium and tendon
0.829 0.171 0.000
J90 Pleural effusion, not elsewhere classified
0.828 0.172 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.827 0.173 0.000
H33 Retinal detachments and breaks
0.827 0.173 0.000
I77.6 Arteritis, unspecified
0.826 0.174 0.000
D69 Purpura and other haemorrhagic conditions
0.826 0.174 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.825 0.175 0.000
W19.9 Unspecified place
0.824 0.176 0.000
E03.8 Other specified hypothyroidism
0.823 0.177 0.000
C88 Malignant immunoproliferative diseases
0.822 0.178 0.000
C92 Myeloid leukaemia
0.821 0.179 0.000
E20 Hypoparathyroidism
0.820 0.180 0.000
H30 Chorioretinal inflammation
0.820 0.180 0.000
L30.9 Dermatitis, unspecified
0.820 0.180 0.000
B44.9 Aspergillosis, unspecified
0.819 0.181 0.000
C25.2 Tail of pancreas
0.815 0.185 0.000
G31.8 Other specified degenerative diseases of nervous system
0.813 0.187 0.000
E13 Other specified diabetes mellitus
0.813 0.187 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.812 0.188 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.811 0.189 0.000
M33 Dermatopolymyositis
0.810 0.190 0.000
E11.0 With coma
0.809 0.191 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.808 0.192 0.000
K90.8 Other intestinal malabsorption
0.807 0.193 0.000
E11.7 With multiple complications
0.807 0.193 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.806 0.194 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.805 0.195 0.000
G70-G73 Diseases of myoneural junction and muscle
0.803 0.197 0.000
E14.4 With neurological complications
0.803 0.197 0.000
C04.0 Anterior floor of mouth
0.799 0.201 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.799 0.201 0.000
L50.0 Allergic urticaria
0.797 0.203 0.000
L89 Decubitus ulcer
0.796 0.204 0.000
C78.0 Secondary malignant neoplasm of lung
0.796 0.204 0.000
M32 Systemic lupus erythematosus
0.793 0.206 0.000
W50-W64 Exposure to animate mechanical forces
0.793 0.207 0.000
B02.9 Zoster without complication
0.792 0.208 0.000
C95 Leukaemia of unspecified cell type
0.792 0.208 0.000
H43.2 Crystalline deposits in vitreous body
0.791 0.209 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.791 0.209 0.000
C18.1 Appendix
0.790 0.210 0.000
C18.2 Ascending colon
0.790 0.210 0.000
C13 Malignant neoplasm of hypopharynx
0.789 0.211 0.000
H46 Optic neuritis
0.788 0.212 0.000
E14.5 With peripheral circulatory complications
0.787 0.213 0.000
L81 Other disorders of pigmentation
0.786 0.213 0.000
E53 Deficiency of other B group vitamins
0.786 0.214 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.784 0.216 0.000
A15-A19 Tuberculosis
0.783 0.217 0.000
E14.1 With ketoacidosis
0.782 0.218 0.000
M62 Other disorders of muscle
0.782 0.218 0.000
C10 Malignant neoplasm of oropharynx
0.782 0.218 0.000
B25 Cytomegaloviral disease
0.782 0.218 0.000
E21.3 Hyperparathyroidism, unspecified
0.782 0.218 0.000
M00 Pyogenic arthritis
0.781 0.219 0.000
C84.5 Other and unspecified T-cell lymphomas
0.781 0.219 0.000
C23 Malignant neoplasm of gallbladder
0.781 0.219 0.000
L40-L45 Papulosquamous disorders
0.781 0.219 0.000
E14.2 Withrenal complications
0.778 0.222 0.000
D83 Common variable immunodeficiency
0.777 0.222 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.777 0.223 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.777 0.223 0.000
M21 Other acquired deformities of limbs
0.776 0.224 0.000
C18.7 Sigmoid colon
0.776 0.224 0.000
E14.8 With unspecified complications
0.776 0.224 0.000
C91.4 Hairy-cell leukaemia
0.774 0.226 0.000
E14.6 With other specified complications
0.774 0.226 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.774 0.226 0.000
M76 Enthesopathies of lower limb, excluding foot
0.773 0.227 0.000
C04.9 Floor of mouth, unspecified
0.772 0.227 0.000
W75-W84 Other accidental threats to breathing
0.772 0.228 0.000
E23.2 Diabetes insipidus
0.771 0.229 0.000
C38.4 Pleura
0.771 0.229 0.000
H16 Keratitis
0.767 0.233 0.000
M34.9 Systemic sclerosis, unspecified
0.766 0.234 0.000
C11 Malignant neoplasm of nasopharynx
0.766 0.234 0.000
M86.6 Other chronic osteomyelitis
0.765 0.235 0.000
C05 Malignant neoplasm of palate
0.765 0.235 0.000
K72.1 Chronic hepatic failure
0.764 0.235 0.000
L91 Hypertrophic disorders of skin
0.764 0.236 0.000
M34.1 CR(E)ST syndrome
0.764 0.236 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.764 0.236 0.000
C07 Malignant neoplasm of parotid gland
0.764 0.236 0.000
B01 Varicella [chickenpox]
0.764 0.236 0.000
H34.1 Central retinal artery occlusion
0.763 0.237 0.000
E10.0 With coma
0.763 0.237 0.000
I74.8 Embolism and thrombosis of other arteries
0.762 0.238 0.000
X23 Contact with hornets, wasps and bees
0.762 0.238 0.000
E11.1 With ketoacidosis
0.762 0.238 0.000
H33.3 Retinal breaks without detachment
0.761 0.239 0.000
I77.2 Rupture of artery
0.761 0.239 0.000
M31.6 Other giant cell arteritis
0.760 0.240 0.000
L13 Other bullous disorders
0.760 0.240 0.000
L94.0 Localised scleroderma [morphea]
0.759 0.241 0.000
J45.8 Mixed asthma
0.757 0.242 0.000
C16 Malignant neoplasm of stomach
0.758 0.242 0.000
H05 Disorders of orbit
0.757 0.243 0.000
D84 Other immunodeficiencies
0.755 0.244 0.000
D69.6 Thrombocytopenia, unspecified
0.755 0.245 0.000
G51.9 Disorder of facial nerve, unspecified
0.753 0.247 0.000
B44.1 Other pulmonary aspergillosis
0.753 0.247 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.753 0.247 0.000
E11.6 With other specified complications
0.751 0.249 0.000
L81.9 Disorder of pigmentation, unspecified
0.749 0.251 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.749 0.251 0.000
V70-V79 Bus occupant injured in transport accident
0.749 0.251 0.000
C03 Malignant neoplasm of gum
0.749 0.251 0.000
C84.0 Mycosis fungoides
0.747 0.253 0.000
G31.0 Circumscribed brain atrophy
0.747 0.253 0.000
M35.2 Behcet's disease
0.747 0.253 0.000
C91.9 Lymphoid leukaemia, unspecified
0.746 0.254 0.000
K71 Toxic liver disease
0.746 0.254 0.000
D69.4 Other primary thrombocytopenia
0.746 0.254 0.000
D61.1 Drug-induced aplastic anaemia
0.745 0.255 0.000
L50.1 Idiopathic urticaria
0.745 0.255 0.000
L94.2 Calcinosis cutis
0.745 0.255 0.000
C18.8 Overlapping lesion of colon
0.745 0.255 0.000
M86.8 Other osteomyelitis
0.744 0.256 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.744 0.256 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.743 0.257 0.000
H43.9 Disorder of vitreous body, unspecified
0.743 0.257 0.000
D86.0 Sarcoidosis of lung
0.742 0.258 0.000
E24.2 Drug-induced Cushing's syndrome
0.742 0.258 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.741 0.258 0.000
E06 Thyroiditis
0.740 0.260 0.000
C91.0 Acute lymphoblastic leukaemia
0.740 0.260 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.740 0.260 0.000
E05.8 Other thyrotoxicosis
0.739 0.261 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.739 0.261 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.737 0.263 0.000
L23 Allergic contact dermatitis
0.737 0.263 0.000
E10.8 With unspecified complications
0.737 0.263 0.000
M17.9 Gonarthrosis, unspecified
0.735 0.265 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.733 0.267 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.733 0.267 0.000
M05-M14 Inflammatory polyarthropathies
0.733 0.267 0.000
W22 Striking against or struck by other objects
0.732 0.268 0.000
B25.9 Cytomegaloviral disease, unspecified
0.732 0.268 0.000
B36 Other superficial mycoses
0.731 0.269 0.000
V01-V09 Pedestrian injured in transport accident
0.731 0.269 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.731 0.269 0.000
E10.5 With peripheral circulatory complications
0.731 0.269 0.000
E25 Adrenogenital disorders
0.731 0.269 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.731 0.269 0.000
H31 Other disorders of choroid
0.730 0.269 0.000
H44.2 Degenerative myopia
0.730 0.270 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.729 0.271 0.000
X10-X19 Contact with heat and hot substances
0.727 0.273 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.726 0.274 0.000
D86.8 Sarcoidosis of other and combined sites
0.725 0.275 0.000
E53.8 Deficiency of other specified B group vitamins
0.725 0.275 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.724 0.276 0.000
E07 Other disorders of thyroid
0.724 0.276 0.000
C25.1 Body of pancreas
0.722 0.278 0.000
M34.8 Other forms of systemic sclerosis
0.722 0.278 0.000
C25.7 Other parts of pancreas
0.721 0.279 0.000
L43 Lichen planus
0.721 0.279 0.000
B02.2 Zoster with other nervous system involvement
0.720 0.280 0.000
L53.0 Toxic erythema
0.720 0.280 0.000
E86 Volume depletion
0.720 0.280 0.000
L53.9 Erythematous condition, unspecified
0.720 0.280 0.000
V90-V94 Water transport accidents
0.719 0.281 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.719 0.281 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.719 0.281 0.000
H34.9 Retinal vascular occlusion, unspecified
0.719 0.281 0.000
H44.0 Purulent endophthalmitis
0.718 0.282 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.716 0.283 0.000
D64.3 Other sideroblastic anaemias
0.716 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.716 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.716 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.716 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.284 0.000
L95.9 Vasculitis limited to skin, unspecified
0.716 0.284 0.000
M00.9 Pyogenic arthritis, unspecified
0.716 0.284 0.000
C93 Monocytic leukaemia
0.716 0.284 0.000
D82 Immunodeficiency associated with other major defects
0.716 0.284 0.000
D81 Combined immunodeficiencies
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.284 0.000
E16.3 Increased secretion of glucagon
0.715 0.284 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.715 0.285 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.715 0.285 0.000
W45 Foreign body or object entering through skin
0.715 0.285 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.715 0.285 0.000
C85.0 Lymphosarcoma
0.715 0.285 0.000
J45.1 Nonallergic asthma
0.715 0.285 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.715 0.285 0.000
E32 Diseases of thymus
0.715 0.285 0.000
E31 Polyglandular dysfunction
0.715 0.285 0.000
E30 Disorders of puberty, not elsewhere classified
0.715 0.285 0.000
C09 Malignant neoplasm of tonsil
0.715 0.285 0.000
J41.0 Simple chronic bronchitis
0.715 0.285 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.715 0.285 0.000
E14.7 With multiple complications
0.714 0.285 0.000
E14.0 With coma
0.714 0.285 0.000
E16.1 Other hypoglycaemia
0.713 0.286 0.000
C25.8 Overlapping lesion of pancreas
0.713 0.286 0.000
C25.4 Endocrine pancreas
0.713 0.286 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.713 0.287 0.000
C00 Malignant neoplasm of lip
0.712 0.287 0.000
E10.6 With other specified complications
0.712 0.288 0.000
E27.5 Adrenomedullary hyperfunction
0.712 0.288 0.000
E27.0 Other adrenocortical overactivity
0.712 0.288 0.000
D61.8 Other specified aplastic anaemias
0.711 0.289 0.000
D61.3 Idiopathic aplastic anaemia
0.711 0.289 0.000
D61.2 Aplastic anaemia due to other external agents
0.711 0.289 0.000
D61.0 Constitutional aplastic anaemia
0.711 0.289 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.711 0.289 0.000
C92.0 Acute myeloid leukaemia
0.711 0.289 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.711 0.289 0.000
L54 Erythema in diseases classified elsewhere
0.711 0.289 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.710 0.290 0.000
L87 Transepidermal elimination disorders
0.710 0.290 0.000
L86 Keratoderma in diseases classified elsewhere
0.710 0.290 0.000
E74 Other disorders of carbohydrate metabolism
0.710 0.290 0.000
L20 Atopic dermatitis
0.710 0.290 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.710 0.290 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.710 0.290 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.710 0.290 0.000
V23.4 Driver injured in traffic accident
0.710 0.290 0.000
W19.3 Sports and athletics area
0.710 0.290 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.709 0.290 0.000
B37.2 Candidiasis of skin and nail
0.709 0.291 0.000
E83 Disorders of mineral metabolism
0.634 0.292 0.074
M89.3 Hypertrophy of bone
0.707 0.293 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.705 0.295 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.705 0.295 0.000
Q43 Other congenital malformations of intestine
0.705 0.295 0.000
B00 Herpesviral [herpes simplex] infections
0.704 0.295 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.296 0.704
M88 Paget's disease of bone [osteitis deformans]
0.704 0.296 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.703 0.297 0.000
C81.1 Nodular sclerosis
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
B48 Other mycoses, not elsewhere classified
0.702 0.298 0.000
B47 Mycetoma
0.702 0.298 0.000
B46 Zygomycosis
0.702 0.298 0.000
B45 Cryptococcosis
0.702 0.298 0.000
B43 Chromomycosis and phaeomycotic abscess
0.702 0.298 0.000
B42 Sporotrichosis
0.702 0.298 0.000
B41 Paracoccidioidomycosis
0.702 0.298 0.000
B40 Blastomycosis
0.702 0.298 0.000
B39 Histoplasmosis
0.702 0.298 0.000
B38 Coccidioidomycosis
0.702 0.298 0.000
G51.0 Bell's palsy
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.700 0.299 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.700 0.300 0.000
A65-A69 Other spirochaetal diseases
0.700 0.300 0.000
I77.5 Necrosis of artery
0.700 0.300 0.000
I77.4 Coeliac artery compression syndrome
0.700 0.300 0.000
I77.3 Arterial fibromuscular dysplasia
0.700 0.300 0.000
B07 Viral warts
0.700 0.300 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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