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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523504
log Bayes Factor = 80.1361
Chromosome 6   position 31,510,858  (GRCh37) Explore rs2523504 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E14.3 With ophthalmic complications
0.000 0.002 0.998
I10 Essential (primary) hypertension
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
I10-I15 Hypertensive diseases
0.000 0.002 0.998
Chapter IX Diseases of the circulatory system
0.000 0.002 0.998
# Top node
0.000 0.003 0.997
E14.9 Without complications
0.000 0.005 0.995
K90 Intestinal malabsorption
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.007 0.993
Chapter XI Diseases of the digestive system
0.000 0.007 0.993
K90-K93 Other diseases of the digestive system
0.000 0.009 0.991
E78.0 Pure hypercholesterolaemia
0.000 0.010 0.990
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.010 0.990
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.011 0.989
L40.5 Arthropathic psoriasis
0.000 0.012 0.988
E10.4 With neurological complications
0.000 0.014 0.986
E70-E90 Metabolic disorders
0.000 0.014 0.986
G35-G37 Demyelinating diseases of the central nervous system
0.985 0.015 0.000
K70-K77 Diseases of liver
0.000 0.016 0.984
H36.0 Diabetic retinopathy
0.000 0.017 0.983
G37 Other demyelinating diseases of central nervous system
0.983 0.017 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.018 0.982
H30-H36 Disorders of choroid and retina
0.000 0.019 0.981
Chapter VIII Diseases of the ear and mastoid process
0.000 0.020 0.980
I24 Other acute ischaemic heart diseases
0.000 0.021 0.979
G37.9 Demyelinating disease of central nervous system, unspecified
0.977 0.023 0.000
H35 Other retinal disorders
0.000 0.024 0.976
H35.8 Other specified retinal disorders
0.000 0.031 0.969
Chapter VII Diseases of the eye and adnexa
0.000 0.032 0.968
K74 Fibrosis and cirrhosis of liver
0.000 0.035 0.965
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.038 0.962
L43 Lichen planus
0.000 0.040 0.960
I25.5 Ischaemic cardiomyopathy
0.000 0.046 0.954
H60-H62 Diseases of external ear
0.000 0.046 0.954
I22 Subsequent myocardial infarction
0.000 0.047 0.953
I24.8 Other forms of acute ischaemic heart disease
0.000 0.051 0.949
H65-H75 Diseases of middle ear and mastoid
0.000 0.057 0.943
K50-K52 Noninfective enteritis and colitis
0.000 0.062 0.938
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.066 0.934
K52 Other non-infective gastro-enteritis and colitis
0.000 0.067 0.933
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.071 0.929
E78.8 Other disorders of lipoprotein metabolism
0.000 0.080 0.920
I20 Angina pectoris
0.000 0.083 0.917
K74.6 Other and unspecified cirrhosis of liver
0.000 0.085 0.915
E13 Other specified diabetes mellitus
0.000 0.087 0.913
H71 Cholesteatoma of middle ear
0.000 0.091 0.909
H66 Suppurative and unspecified otitis media
0.000 0.091 0.909
L43.9 Lichen planus, unspecified
0.000 0.092 0.908
I20.9 Angina pectoris, unspecified
0.000 0.093 0.907
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.099 0.901
H66.3 Other chronic suppurative otitis media
0.000 0.099 0.901
J45 Asthma
0.000 0.104 0.896
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.111 0.889
E10.8 With unspecified complications
0.000 0.112 0.888
E16 Other disorders of pancreatic internal secretion
0.000 0.113 0.887
E10.5 With peripheral circulatory complications
0.000 0.114 0.886
H61 Other disorders of external ear
0.000 0.117 0.883
H60 Otitis externa
0.000 0.117 0.883
I25.2 Old myocardial infarction
0.000 0.122 0.878
E10.2 With renal complications
0.000 0.125 0.875
E78.2 Mixed hyperlipidaemia
0.000 0.127 0.873
K74.5 Biliary cirrhosis, unspecified
0.000 0.129 0.871
G37.8 Other specified demyelinating diseases of central nervous system
0.871 0.129 0.000
E11.6 With other specified complications
0.000 0.137 0.863
J40-J47 Chronic lower respiratory diseases
0.000 0.138 0.862
E10.0 With coma
0.000 0.139 0.861
E00-E07 Disorders of thyroid gland
0.000 0.142 0.858
Chapter X Diseases of the respiratory system
0.000 0.144 0.856
I11 Hypertensive heart disease
0.000 0.149 0.851
E13.9 Without complications
0.000 0.150 0.850
K75 Other inflammatory liver diseases
0.000 0.151 0.849
E11.0 With coma
0.000 0.153 0.847
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.158 0.842
E16.2 Hypoglycaemia, unspecified
0.000 0.160 0.840
H35.2 Other proliferative retinopathy
0.000 0.160 0.840
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.161 0.839
E03 Other hypothyroidism
0.000 0.163 0.837
K76 Other diseases of liver
0.000 0.167 0.833
E03.9 Hypothyroidism, unspecified
0.000 0.173 0.827
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.174 0.826
K73 Chronic hepatitis, not elsewhere classified
0.000 0.174 0.826
L50-L54 Urticaria and erythema
0.000 0.176 0.824
K52.1 Toxic gastro-enteritis and colitis
0.000 0.182 0.818
L43.8 Other lichen planus
0.000 0.186 0.814
J43 Emphysema
0.000 0.191 0.809
E11.1 With ketoacidosis
0.000 0.194 0.806
I15 Secondary hypertension
0.000 0.198 0.802
L40.8 Other psoriasis
0.000 0.204 0.796
L40.1 Generalised pustular psoriasis
0.000 0.208 0.792
E74 Other disorders of carbohydrate metabolism
0.000 0.209 0.790
E11.3 With ophthalmic complications
0.000 0.210 0.790
E83.1 Disorders of iron metabolism
0.790 0.210 0.000
E14.8 With unspecified complications
0.000 0.212 0.788
H35.7 Separation of retinal layers
0.000 0.214 0.786
E10.6 With other specified complications
0.000 0.216 0.783
L42 Pityriasis rosea
0.000 0.217 0.783
H35.5 Hereditary retinal dystrophy
0.000 0.220 0.780
K76.9 Liver disease, unspecified
0.000 0.220 0.780
K75.4 Autoimmune hepatitis
0.000 0.220 0.780
H35.0 Background retinopathy and retinal vascular changes
0.000 0.220 0.780
K74.3 Primary biliary cirrhosis
0.000 0.220 0.780
E14.6 With other specified complications
0.000 0.221 0.779
H61.1 Non-infective disorders of pinna
0.000 0.226 0.774
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.231 0.769
E78.6 Lipoprotein deficiency
0.000 0.233 0.767
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.234 0.766
H61.3 Acquired stenosis of external ear canal
0.000 0.234 0.766
I25.3 Aneurysm of heart
0.000 0.238 0.762
H60.3 Other infective otitis externa
0.000 0.241 0.759
I23 Certain current complications following acute myocardial infarction
0.000 0.242 0.758
H43-H45 Disorders of vitreous body and globe
0.000 0.242 0.758
K72 Hepatic failure, not elsewhere classified
0.000 0.244 0.756
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.244 0.756
J43.9 Emphysema, unspecified
0.000 0.247 0.753
H53-H54 Visual disturbances and blindness
0.000 0.249 0.751
K90.8 Other intestinal malabsorption
0.000 0.257 0.743
E85 Amyloidosis
0.000 0.258 0.742
E11.2 With renal complications
0.000 0.259 0.741
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.260 0.739
L40.3 Pustulosis palmaris et plantaris
0.000 0.261 0.739
E14.1 With ketoacidosis
0.000 0.262 0.738
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.737 0.263 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.268 0.732
H35.6 Retinal haemorrhage
0.000 0.270 0.730
H31 Other disorders of choroid
0.000 0.275 0.725
K73.9 Chronic hepatitis, unspecified
0.000 0.278 0.722
E14.4 With neurological complications
0.000 0.278 0.722
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.279 0.721
L10-L14 Bullous disorders
0.000 0.279 0.721
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.280 0.720
H34 Retinal vascular occlusions
0.000 0.281 0.719
E16.1 Other hypoglycaemia
0.000 0.283 0.717
H61.9 Disorder of external ear, unspecified
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
H61.2 Impacted cerumen
0.000 0.284 0.716
I13 Hypertensive heart and renal disease
0.000 0.284 0.715
H74 Other disorders of middle ear and mastoid
0.000 0.285 0.715
I00-I02 Acute rheumatic fever
0.000 0.285 0.715
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.285 0.714
G36 Other acute disseminated demyelination
0.714 0.286 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.287 0.713
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.287 0.713
K90.1 Tropical sprue
0.000 0.287 0.713
K83 Other diseases of biliary tract
0.000 0.288 0.712
E88 Other metabolic disorders
0.000 0.289 0.711
E79 Disorders of purine and pyrimidine metabolism
0.000 0.289 0.711
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.289 0.711
E78.3 Hyperchylomicronaemia
0.000 0.291 0.709
E14.5 With peripheral circulatory complications
0.000 0.291 0.709
E77 Disorders of glycoprotein metabolism
0.000 0.293 0.707
E76 Disorders of glycosaminoglycan metabolism
0.000 0.293 0.707
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.293 0.707
E70 Disorders of aromatic amino-acid metabolism
0.000 0.293 0.707
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.293 0.707
K83.0 Cholangitis
0.000 0.294 0.706
K77 Liver disorders in diseases classified elsewhere
0.000 0.294 0.706
E11.4 With neurological complications
0.000 0.295 0.705
G37.5 Concentric sclerosis [Balo]
0.704 0.295 0.000
G37.4 Subacute necrotising myelitis
0.704 0.295 0.000
G37.2 Central pontine myelinolysis
0.704 0.295 0.000
G37.1 Central demyelination of corpus callosum
0.704 0.295 0.000
G37.0 Diffuse sclerosis
0.704 0.295 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.296 0.704
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.296 0.704
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.296 0.703
K71 Toxic liver disease
0.000 0.297 0.703
E83 Disorders of mineral metabolism
0.679 0.298 0.022
I25.4 Coronary artery aneurysm
0.000 0.299 0.701
J46 Status asthmaticus
0.000 0.300 0.700
H35.1 Retinopathy of prematurity
0.000 0.300 0.700
K60.2 Anal fissure, unspecified
0.000 0.302 0.698
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.307 0.693
H35.4 Peripheral retinal degeneration
0.000 0.307 0.693
H60.9 Otitis externa, unspecified
0.000 0.307 0.693
K74.4 Secondary biliary cirrhosis
0.000 0.308 0.692
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.308 0.692
K74.1 Hepatic sclerosis
0.000 0.308 0.692
H60.5 Acute otitis externa, non-infective
0.000 0.308 0.692
K60 Fissure and fistula of anal and rectal regions
0.000 0.309 0.691
K75.8 Other specified inflammatory liver diseases
0.000 0.310 0.690
L52 Erythema nodosum
0.000 0.310 0.690
K55-K64 Other diseases of intestines
0.000 0.310 0.690
L43.3 Subacute (active) lichen planus
0.000 0.312 0.688
L43.2 Lichenoid drug reaction
0.000 0.312 0.688
L43.1 Bullous lichen planus
0.000 0.312 0.688
L43.0 Hypertrophic lichen planus
0.000 0.312 0.688
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.312 0.688
K76.8 Other specified diseases of liver
0.000 0.313 0.687
K86 Other diseases of pancreas
0.000 0.314 0.686
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.316 0.684
I20.0 Unstable angina
0.000 0.321 0.679
J60-J70 Lung diseases due to external agents
0.000 0.322 0.678
H66.4 Suppurative otitis media, unspecified
0.000 0.322 0.678
H30 Chorioretinal inflammation
0.000 0.324 0.676
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.324 0.676
H68 Eustachian salpingitis and obstruction
0.000 0.324 0.676
H67 Otitis media in diseases classified elsewhere
0.000 0.324 0.676
E78.1 Pure hyperglyceridaemia
0.000 0.325 0.675
H70 Mastoiditis and related conditions
0.000 0.325 0.675
H43 Disorders of vitreous body
0.000 0.326 0.674
E72 Other disorders of amino-acid metabolism
0.000 0.326 0.674
E78.5 Hyperlipidaemia, unspecified
0.000 0.328 0.672
H60.4 Cholesteatoma of external ear
0.000 0.329 0.671
J42 Unspecified chronic bronchitis
0.000 0.330 0.670
E15 Nondiabetic hypoglycaemic coma
0.000 0.330 0.670
E83.3 Disorders of phosphorus metabolism
0.662 0.335 0.003
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.335 0.665
H60.8 Other otitis externa
0.000 0.337 0.663
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.337 0.663
E84 Cystic fibrosis
0.000 0.337 0.663
H72 Perforation of tympanic membrane
0.000 0.342 0.658
H54 Blindness and low vision
0.000 0.343 0.657
K58 Irritable bowel syndrome
0.000 0.344 0.656
K90.9 Intestinal malabsorption, unspecified
0.000 0.344 0.656
E13.8 With unspecified complications
0.000 0.345 0.654
E13.7 With multiple complications
0.000 0.345 0.654
E13.6 With other specified complications
0.000 0.345 0.654
E13.5 With peripheral circulatory complications
0.000 0.345 0.654
E13.4 With neurological complications
0.000 0.345 0.654
E13.3 With ophthalmic complications
0.000 0.345 0.654
E13.2 With renal complications
0.000 0.345 0.654
E13.1 With ketoacidosis
0.000 0.345 0.654
E13.0 With coma
0.000 0.345 0.654
H90-H95 Other disorders of ear
0.000 0.348 0.652
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.349 0.650
J90-J94 Other diseases of pleura
0.000 0.350 0.650
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.351 0.649
L51 Erythema multiforme
0.000 0.353 0.646
E11.5 With peripheral circulatory complications
0.000 0.354 0.646
J43.2 Centrilobular emphysema
0.000 0.354 0.646
H66.0 Acute suppurative otitis media
0.000 0.356 0.644
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.357 0.643
J45.1 Nonallergic asthma
0.000 0.357 0.642
K86.1 Other chronic pancreatitis
0.000 0.359 0.641
H60.1 Cellulitis of external ear
0.000 0.361 0.639
E40-E46 Malnutrition
0.000 0.362 0.638
K74.0 Hepatic fibrosis
0.000 0.362 0.638
L50 Urticaria
0.000 0.362 0.638
H60.0 Abscess of external ear
0.000 0.362 0.637
H54.9 Unspecified visual impairment (binocular)
0.000 0.363 0.637
J92 Pleural plaque
0.000 0.363 0.637
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.364 0.636
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.364 0.636
E16.4 Abnormal secretion of gastrin
0.000 0.364 0.636
E16.3 Increased secretion of glucagon
0.000 0.364 0.636
H35.9 Retinal disorder, unspecified
0.000 0.365 0.635
E78.4 Other hyperlipidaemia
0.000 0.366 0.634
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.366 0.634
H60.2 Malignant otitis externa
0.000 0.367 0.633
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.368 0.632
I15.1 Hypertension secondary to other renal disorders
0.000 0.370 0.630
L40.0 Psoriasis vulgaris
0.000 0.371 0.629
J92.9 Pleural plaque without asbestos
0.000 0.375 0.625
I12 Hypertensive renal disease
0.000 0.377 0.623
E88.2 Lipomatosis, not elsewhere classified
0.000 0.379 0.621
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.380 0.620
K72.9 Hepatic failure, unspecified
0.000 0.380 0.620
K60.0 Acute anal fissure
0.000 0.380 0.620
I24.1 Dressler's syndrome
0.000 0.384 0.616
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.385 0.615
E00 Congenital iodine-deficiency syndrome
0.000 0.385 0.615
H74.4 Polyp of middle ear
0.000 0.388 0.612
K75.2 Nonspecific reactive hepatitis
0.000 0.391 0.609
K75.1 Phlebitis of portal vein
0.000 0.391 0.609
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.391 0.609
J69 Pneumonitis due to solids and liquids
0.000 0.393 0.607
K86.2 Cyst of pancreas
0.000 0.394 0.606
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.394 0.606
H73 Other disorders of tympanic membrane
0.000 0.397 0.603
E85.9 Amyloidosis, unspecified
0.000 0.399 0.601
J95-J99 Other diseases of the respiratory system
0.000 0.399 0.601
E03.5 Myxoedema coma
0.000 0.400 0.600
E03.4 Atrophy of thyroid (acquired)
0.000 0.400 0.600
E03.3 Postinfectious hypothyroidism
0.000 0.400 0.600
E03.1 Congenital hypothyroidism without goitre
0.000 0.400 0.600
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.400 0.600
E89.3 Postprocedural hypopituitarism
0.000 0.401 0.599
I15.9 Seconday hypertension, unspecified
0.000 0.402 0.598
L13 Other bullous disorders
0.000 0.402 0.598
K76.5 Hepatic veno-occlusive disease
0.000 0.402 0.597
K76.4 Peliosis hepatis
0.000 0.402 0.597
K76.3 Infarction of liver
0.000 0.402 0.597
K76.2 Central haemorrhagic necrosis of liver
0.000 0.402 0.597
J43.8 Other emphysema
0.000 0.403 0.597
I15.0 Renovascular hypertension
0.000 0.405 0.595
E05.9 Thyrotoxicosis, unspecified
0.000 0.406 0.594
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.408 0.592
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.408 0.592
L54 Erythema in diseases classified elsewhere
0.000 0.409 0.591
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.410 0.590
H90 Conductive and sensorineural hearing loss
0.000 0.410 0.590
H55-H59 Other disorders of eye and adnexa
0.000 0.410 0.590
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.413 0.587
I23.8 Other current complications following acute myocardial infarction
0.000 0.415 0.585
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.416 0.584
H34.8 Other retinal vascular occlusions
0.000 0.416 0.584
J43.1 Panlobular emphysema
0.000 0.420 0.580
J43.0 MacLeod's syndrome
0.000 0.420 0.580
J85 Abscess of lung and mediastinum
0.000 0.420 0.580
J86 Pyothorax
0.000 0.421 0.579
J41 Simple and mucopurulent chronic bronchitis
0.000 0.422 0.578
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.423 0.577
I15.8 Other secondary hypertension
0.000 0.425 0.575
I15.2 Hypertension secondary to endocrine disorders
0.000 0.425 0.575
I22.8 Subsequent myocardial infarction of other sites
0.000 0.425 0.575
M45 Ankylosing spondylitis
0.000 0.428 0.572
H47.3 Other disorders of optic disk
0.000 0.430 0.570
H43.2 Crystalline deposits in vitreous body
0.000 0.430 0.570
E07 Other disorders of thyroid
0.000 0.431 0.569
J45.8 Mixed asthma
0.000 0.432 0.568
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.433 0.567
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.433 0.567
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.433 0.567
E74.2 Disorders of galactose metabolism
0.000 0.433 0.567
E74.1 Disorders of fructose metabolism
0.000 0.433 0.567
E74.0 Glycogen storage disease
0.000 0.433 0.567
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.435 0.565
H43.9 Disorder of vitreous body, unspecified
0.000 0.437 0.563
J69.0 Pneumonitis due to food and vomit
0.000 0.440 0.560
H31.0 Chorioretinal scars
0.000 0.444 0.556
H31.1 Choroidal degeneration
0.000 0.445 0.555
K60.5 Anorectal fistula
0.000 0.445 0.555
H54.7 Unspecified visual loss
0.000 0.446 0.554
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.448 0.552
H90.5 Sensorineural hearing loss, unspecified
0.000 0.450 0.550
E75.5 Other lipid storage disorders
0.000 0.450 0.550
E73 Lactose intolerance
0.000 0.451 0.549
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.451 0.549
E50-E64 Other nutritional deficiencies
0.000 0.452 0.548
H72.0 Central perforation of tympanic membrane
0.000 0.454 0.546
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.454 0.545
H72.2 Other marginal perforations of tympanic membrane
0.000 0.455 0.545
K83.3 Fistula of bile duct
0.000 0.455 0.545
E88.3 Tumour lysis syndrome
0.000 0.456 0.544
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.456 0.544
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.456 0.544
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.456 0.544
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.456 0.544
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.456 0.544
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.456 0.544
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.456 0.544
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.456 0.544
K86.3 Pseudocyst of pancreas
0.000 0.456 0.544
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.457 0.543
H61.8 Other specified disorders of external ear
0.000 0.457 0.542
K72.1 Chronic hepatic failure
0.000 0.458 0.542
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.458 0.542
H43.3 Other vitreous opacities
0.000 0.460 0.540
K81 Cholecystitis
0.000 0.461 0.539
K75.9 Inflammatory liver disease, unspecified
0.000 0.464 0.536
E85.3 Secondary systemic amyloidosis
0.000 0.466 0.534
K75.0 Abscess of liver
0.000 0.467 0.532
E85.8 Other amyloidosis
0.000 0.468 0.532
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.468 0.532
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.468 0.532
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.468 0.532
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.469 0.531
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.470 0.530
K60.4 Rectal fistula
0.000 0.471 0.529
H47.2 Optic atrophy
0.000 0.471 0.529
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.474 0.526
E75.6 Lipid storage disorder, unspecified
0.000 0.475 0.525
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.475 0.525
E75.3 Sphingolipidosis, unspecified
0.000 0.475 0.525
E75.2 Other sphingolipidosis
0.000 0.475 0.525
E75.1 Other gangliosidosis
0.000 0.475 0.525
E75.0 GM2 gangliosidosis
0.000 0.475 0.525
H72.8 Other perforations of tympanic membrane
0.000 0.475 0.525
I12.9 Hypertensive renal disease without renal failure
0.000 0.480 0.520
H31.9 Disorder of choroid, unspecified
0.000 0.480 0.519
H31.4 Choroidal detachment
0.000 0.480 0.519
H31.2 Hereditary choroidal dystrophy
0.000 0.480 0.519
H34.9 Retinal vascular occlusion, unspecified
0.000 0.481 0.519
G36.0 Neuromyelitis optica [Devic]
0.519 0.481 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.481 0.519
E05.5 Thyroid crisis or storm
0.000 0.483 0.517
E05.4 Thyrotoxicosis factitia
0.000 0.483 0.517
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.483 0.517
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.483 0.517
L10 Pemphigus
0.000 0.483 0.517
L14 Bullous disorders in diseases classified elsewhere
0.000 0.483 0.517
K76.1 Chronic passive congestion of liver
0.000 0.483 0.517
H34.0 Transient retinal artery occlusion
0.000 0.484 0.516
E88.8 Other specified metabolic disorders
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
K52.3 Indeterminate colitis
0.000 0.486 0.514
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.486 0.514
H31.3 Choroidal haemorrhage and rupture
0.000 0.486 0.514
L41.9 Parapsoriasis, unspecified
0.000 0.486 0.513
L41.8 Other parapsoriasis
0.000 0.486 0.513
L41.5 Retiform parapsoriasis
0.000 0.486 0.513
L41.4 Large plaque parapsoriasis
0.000 0.486 0.513
L41.3 Small plaque parapsoriasis
0.000 0.486 0.513
L41.2 Lymphomatoid papulosis
0.000 0.486 0.513
L41.1 Pityriasis lichenoides chronica
0.000 0.486 0.513
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.486 0.513
L44.9 Papulosquamous disorder, unspecified
0.000 0.486 0.513
L44.8 Other specified papulosquamous disorders
0.000 0.486 0.513
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.486 0.513
L44.3 Lichen ruber moniliformis
0.000 0.486 0.513
L44.2 Lichen striatus
0.000 0.486 0.513
L44.1 Lichen nitidus
0.000 0.486 0.513
L44.0 Pityriasis rubra pilaris
0.000 0.486 0.513
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.487 0.513
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.487 0.513
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.487 0.513
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.487 0.513
I02 Rheumatic chorea
0.000 0.487 0.513
I01 Rheumatic fever with heart involvement
0.000 0.487 0.513
I00 Rheumatic fever without mention of heart involvement
0.000 0.487 0.513
P90-P96 Other disorders originating in the perinatal period
0.000 0.488 0.512
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.488 0.512
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.488 0.512
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.488 0.512
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.488 0.512
P35-P39 Infections specific to the perinatal period
0.000 0.488 0.512
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.488 0.512
P10-P15 Birth trauma
0.000 0.488 0.512
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.488 0.512
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.488 0.512
G36.9 Acute disseminated demyelination, unspecified
0.512 0.488 0.000
G36.8 Other specified acute disseminated demyelination
0.512 0.488 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.512 0.488 0.000
H92 Otalgia and effusion of ear
0.000 0.489 0.511
K83.5 Biliary cyst
0.000 0.489 0.511
K83.2 Perforation of bile duct
0.000 0.489 0.511
E06 Thyroiditis
0.000 0.490 0.510
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.490 0.510
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.490 0.510
E79.1 Lesch-Nyhan syndrome
0.000 0.490 0.510
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.490 0.510
K93.1 Megacolon in Chagas' disease
0.000 0.490 0.510
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.490 0.510
L13.0 Dermatitis herpetiformis
0.000 0.490 0.510
H70.1 Chronic mastoiditis
0.000 0.493 0.507
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.493 0.507
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.493 0.507
E70.3 Albinism
0.000 0.493 0.507
E70.2 Disorders of tyrosine metabolism
0.000 0.493 0.507
E70.1 Other hyperphenylalaninaemias
0.000 0.493 0.507
E70.0 Classical phenylketonuria
0.000 0.493 0.507
E71.3 Disorders of fatty-acid metabolism
0.000 0.493 0.507
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.493 0.507
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.493 0.507
E71.0 Maple-syrup-urine disease
0.000 0.493 0.507
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.493 0.507
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.493 0.507
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.493 0.507
E76.2 Other mucopolysaccharidoses
0.000 0.493 0.507
E76.1 Mucopolysaccharidosis, type II
0.000 0.493 0.507
E76.0 Mucopolysaccharidosis, type I
0.000 0.493 0.507
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.493 0.507
E77.8 Other disorders of glycoprotein metabolism
0.000 0.493 0.507
E77.1 Defects in glycoprotein degradation
0.000 0.493 0.507
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.493 0.507
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.494 0.506
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.494 0.506
K83.4 Spasm of sphincter of Oddi
0.000 0.494 0.506
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.495 0.504
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.495 0.504
K71.9 Toxic liver disease, unspecified
0.000 0.496 0.504
K71.8 Toxic liver disease with other disorders of liver
0.000 0.496 0.504
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.496 0.504
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.496 0.504

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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