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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2621377
log Bayes Factor = 55.7971
Chromosome 6   position 32,763,110  (GRCh37) Explore rs2621377 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
L40 Psoriasis
0.000 0.004 0.996
H36.0 Diabetic retinopathy
0.000 0.007 0.993
G35-G37 Demyelinating diseases of the central nervous system
0.993 0.007 0.000
C44 Other malignant neoplasms of skin
0.000 0.009 0.991
G37 Other demyelinating diseases of central nervous system
0.991 0.009 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.011 0.989
E27 Other disorders of adrenal gland
0.000 0.012 0.988
C44.7 Skin of lower limb, including hip
0.000 0.013 0.987
G37.9 Demyelinating disease of central nervous system, unspecified
0.984 0.016 0.000
L57.0 Actinic keratosis
0.000 0.020 0.980
E27.1 Primary adrenocortical insufficiency
0.000 0.020 0.980
E03 Other hypothyroidism
0.000 0.020 0.980
L40.9 Psoriasis, unspecified
0.000 0.021 0.979
E11.9 Without complications
0.000 0.024 0.976
E10.1 With ketoacidosis
0.000 0.026 0.974
E03.9 Hypothyroidism, unspecified
0.000 0.029 0.971
C44.3 Skin of other and unspecified parts of face
0.000 0.032 0.968
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.034 0.966
E10.5 With peripheral circulatory complications
0.000 0.034 0.966
E10.2 With renal complications
0.000 0.037 0.963
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.039 0.961
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.041 0.959
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.046 0.954
D04 Carcinoma in situ of skin
0.000 0.046 0.954
Chapter II Neoplasms
0.000 0.052 0.948
D00-D09 In situ neoplasms
0.000 0.053 0.947
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.054 0.946
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.058 0.942
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.060 0.940
E10.4 With neurological complications
0.000 0.062 0.938
L40-L45 Papulosquamous disorders
0.000 0.066 0.934
D04.5 Skin of trunk
0.000 0.070 0.930
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.073 0.927
C44.4 Skin of scalp and neck
0.000 0.081 0.919
D04.7 Skin of lower limb, including hip
0.000 0.090 0.910
E70-E90 Metabolic disorders
0.000 0.091 0.909
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.091 0.908
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.093 0.907
G37.8 Other specified demyelinating diseases of central nervous system
0.901 0.099 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.101 0.899
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.103 0.897
E16 Other disorders of pancreatic internal secretion
0.000 0.104 0.896
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.119 0.881
H36 Retinal disorders in diseases classified elsewhere
0.000 0.120 0.880
D04.3 Skin of other and unspecified parts of face
0.000 0.123 0.877
E23 Hypofunction and other disorders of pituitary gland
0.000 0.126 0.874
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.141 0.859
C83.3 Large cell (diffuse)
0.000 0.150 0.850
C82.0 Small cleaved cell, follicular
0.000 0.152 0.848
E28 Ovarian dysfunction
0.000 0.157 0.843
E10.0 With coma
0.000 0.157 0.843
L40.3 Pustulosis palmaris et plantaris
0.000 0.158 0.842
E11.0 With coma
0.000 0.160 0.840
# Top node
0.000 0.164 0.836
E24 Cushing's syndrome
0.000 0.165 0.835
D09 Carcinoma in situ of other and unspecified sites
0.000 0.168 0.832
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.169 0.831
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.825 0.175 0.000
C91 Lymphoid leukaemia
0.000 0.175 0.825
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.177 0.823
E16.2 Hypoglycaemia, unspecified
0.000 0.178 0.822
M07.3 Other psoriatic arthropathies
0.000 0.180 0.820
D04.4 Skin of scalp and neck
0.000 0.182 0.818
E11.5 With peripheral circulatory complications
0.000 0.189 0.811
C82.2 Large cell, follicular
0.000 0.189 0.811
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.190 0.810
L40.1 Generalised pustular psoriasis
0.000 0.190 0.810
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.194 0.806
E23.7 Disorder of pituitary gland, unspecified
0.000 0.195 0.805
H30-H36 Disorders of choroid and retina
0.000 0.201 0.799
C88 Malignant immunoproliferative diseases
0.000 0.208 0.792
C82.4 Follicular lymphoma grade IIIb
0.000 0.211 0.789
E10.7 With multiple complications
0.000 0.213 0.787
E13 Other specified diabetes mellitus
0.000 0.218 0.782
E65-E68 Obesity and other hyperalimentation
0.000 0.223 0.777
E23.6 Other disorders of pituitary gland
0.000 0.225 0.775
H35 Other retinal disorders
0.000 0.227 0.773
G36 Other acute disseminated demyelination
0.772 0.228 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.229 0.771
D04.6 Skin of upper limb, including shoulder
0.000 0.230 0.770
E78.6 Lipoprotein deficiency
0.000 0.233 0.767
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.239 0.761
L40.4 Guttate psoriasis
0.000 0.245 0.754
Chapter VII Diseases of the eye and adnexa
0.000 0.247 0.753
E79 Disorders of purine and pyrimidine metabolism
0.000 0.248 0.752
E10.6 With other specified complications
0.000 0.248 0.752
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.251 0.749
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.252 0.748
C91.9 Lymphoid leukaemia, unspecified
0.000 0.253 0.747
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.254 0.746
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.257 0.743
D04.9 Skin, unspecified
0.000 0.258 0.742
E78.5 Hyperlipidaemia, unspecified
0.000 0.259 0.741
D09.0 Bladder
0.000 0.260 0.740
E78.2 Mixed hyperlipidaemia
0.000 0.260 0.740
C85.1 B-cell lymphoma, unspecified
0.000 0.260 0.740
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.260 0.740
E89.3 Postprocedural hypopituitarism
0.000 0.266 0.734
D04.2 Skin of ear and external auricular canal
0.000 0.267 0.733
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.268 0.732
C83.7 Burkitt's tumour
0.000 0.270 0.730
Q80-Q89 Other congenital malformations
0.000 0.270 0.730
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.270 0.730
C73 Malignant neoplasm of thyroid gland
0.000 0.275 0.725
H35.2 Other proliferative retinopathy
0.000 0.276 0.724
E40-E46 Malnutrition
0.000 0.279 0.721
E11.2 With renal complications
0.000 0.280 0.720
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.280 0.719
E16.1 Other hypoglycaemia
0.000 0.281 0.719
E24.2 Drug-induced Cushing's syndrome
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
H35.8 Other specified retinal disorders
0.000 0.286 0.714
Q85 Phakomatoses, not elsewhere classified
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
L40.2 Acrodermatitis continua
0.000 0.286 0.714
C43 Malignant melanoma of skin
0.000 0.286 0.714
E26 Hyperaldosteronism
0.000 0.287 0.713
C44.8 Overlapping lesion of skin
0.000 0.290 0.710
G37.5 Concentric sclerosis [Balo]
0.710 0.290 0.000
G37.4 Subacute necrotising myelitis
0.710 0.290 0.000
G37.2 Central pontine myelinolysis
0.710 0.290 0.000
G37.1 Central demyelination of corpus callosum
0.710 0.290 0.000
G37.0 Diffuse sclerosis
0.710 0.290 0.000
H83.0 Labyrinthitis
0.000 0.290 0.710
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.291 0.709
E89.4 Postprocedural ovarian failure
0.000 0.292 0.708
E27.5 Adrenomedullary hyperfunction
0.000 0.292 0.708
E27.0 Other adrenocortical overactivity
0.000 0.292 0.708
E10.8 With unspecified complications
0.000 0.294 0.706
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.294 0.706
H83 Other diseases of inner ear
0.000 0.295 0.705
E03.1 Congenital hypothyroidism without goitre
0.000 0.295 0.705
Chapter VIII Diseases of the ear and mastoid process
0.000 0.295 0.705
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.296 0.704
E89.2 Postprocedural hypoparathyroidism
0.000 0.297 0.703
D06 Carcinoma in situ of cervix uteri
0.000 0.297 0.703
E03.5 Myxoedema coma
0.000 0.298 0.702
E03.4 Atrophy of thyroid (acquired)
0.000 0.298 0.702
E03.3 Postinfectious hypothyroidism
0.000 0.298 0.702
Q60-Q64 Congenital malformations of the urinary system
0.000 0.298 0.702
E88 Other metabolic disorders
0.000 0.300 0.700
E65 Localised adiposity
0.000 0.301 0.699
H80-H83 Diseases of inner ear
0.000 0.301 0.699
E28.2 Polycystic ovarian syndrome
0.000 0.305 0.695
Q61 Cystic kidney disease
0.000 0.309 0.691
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.311 0.689
L43 Lichen planus
0.000 0.312 0.688
C82.6 Cutaneous follicle centre lymphoma
0.000 0.313 0.687
C82.5 Diffuse follicle centre lymphoma
0.000 0.313 0.687
C83.1 Small cleaved cell (diffuse)
0.000 0.313 0.687
E05.8 Other thyrotoxicosis
0.000 0.314 0.686
D04.1 Skin of eyelid, including canthus
0.000 0.316 0.684
C85.0 Lymphosarcoma
0.000 0.316 0.684
D04.8 Skin of other sites
0.000 0.316 0.684
D04.0 Skin of lip
0.000 0.316 0.684
C91.0 Acute lymphoblastic leukaemia
0.000 0.317 0.683
Q50-Q56 Congenital malformations of genital organs
0.000 0.317 0.683
E70 Disorders of aromatic amino-acid metabolism
0.000 0.318 0.682
E22 Hyperfunction of pituitary gland
0.000 0.318 0.682
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.319 0.681
C44.0 Skin of lip
0.000 0.322 0.678
E27.2 Addisonian crisis
0.000 0.324 0.676
E06 Thyroiditis
0.000 0.324 0.676
E15 Nondiabetic hypoglycaemic coma
0.000 0.326 0.674
Q85.8 Other phakomatoses, not elsewhere classified
0.000 0.326 0.674
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.327 0.673
E25 Adrenogenital disorders
0.000 0.330 0.670
L44 Other papulosquamous disorders
0.000 0.331 0.669
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.331 0.669
E28.3 Primary ovarian failure
0.000 0.333 0.667
C94 Other leukaemias of specified cell type
0.000 0.333 0.667
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.334 0.665
L57.5 Actinic granuloma
0.000 0.335 0.664
L57.3 Poikiloderma of Civatte
0.000 0.335 0.664
L57.2 Cutis rhomboidalis nuchae
0.000 0.335 0.664
L57.1 Actinic reticuloid
0.000 0.335 0.664
H30 Chorioretinal inflammation
0.000 0.342 0.658
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.342 0.658
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.342 0.658
H35.6 Retinal haemorrhage
0.000 0.343 0.657
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.345 0.655
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.347 0.652
E77 Disorders of glycoprotein metabolism
0.000 0.348 0.652
E76 Disorders of glycosaminoglycan metabolism
0.000 0.348 0.652
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.348 0.652
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.348 0.652
L55 Sunburn
0.000 0.349 0.651
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.349 0.651
E89.5 Postprocedural testicular hypofunction
0.000 0.349 0.651
L41 Parapsoriasis
0.000 0.350 0.650
C91.5 Adult T-cell leukaemia
0.000 0.351 0.649
E78.1 Pure hyperglyceridaemia
0.000 0.351 0.649
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.351 0.649
E84 Cystic fibrosis
0.000 0.352 0.648
Q61.3 Polycystic kidney, unspecified
0.000 0.352 0.648
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.353 0.647
C86 Other specified types of T/NK-cell lymphoma
0.000 0.353 0.647
D03 Melanoma in situ
0.000 0.354 0.646
C93 Monocytic leukaemia
0.000 0.354 0.645
E24.0 Pituitary-dependent Cushing's disease
0.000 0.356 0.644
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.357 0.643
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.357 0.643
E16.4 Abnormal secretion of gastrin
0.000 0.357 0.643
E16.3 Increased secretion of glucagon
0.000 0.357 0.643
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.359 0.641
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.360 0.640
Q85.9 Phakomatosis, unspecified
0.000 0.361 0.639
E29 Testicular dysfunction
0.000 0.361 0.639
E11.8 With unspecified complications
0.000 0.363 0.637
L10-L14 Bullous disorders
0.000 0.364 0.636
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.367 0.633
C83.6 Undifferentiated (diffuse)
0.000 0.368 0.631
C83.4 Immunoblastic (diffuse)
0.000 0.368 0.631
C83.2 Mixed small and large cell (diffuse)
0.000 0.368 0.631
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.369 0.631
E27.8 Other specified disorders of adrenal gland
0.000 0.370 0.630
C44.2 Skin of ear and external auricular canal
0.000 0.371 0.629
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.373 0.627
E23.1 Drug-induced hypopituitarism
0.000 0.373 0.627
E27.9 Disorder of adrenal gland, unspecified
0.000 0.374 0.626
E11.6 With other specified complications
0.000 0.375 0.625
E03.8 Other specified hypothyroidism
0.000 0.376 0.624
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.377 0.623
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.377 0.623
Q61.0 Congenital single renal cyst
0.000 0.377 0.623
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.381 0.619
E20 Hypoparathyroidism
0.000 0.382 0.618
C95 Leukaemia of unspecified cell type
0.000 0.384 0.616
H35.0 Background retinopathy and retinal vascular changes
0.000 0.385 0.615
L58 Radiodermatitis
0.000 0.385 0.615
E34 Other endocrine disorders
0.000 0.385 0.614
E89.1 Postprocedural hypoinsulinaemia
0.000 0.386 0.614
G36.0 Neuromyelitis optica [Devic]
0.614 0.386 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.387 0.613
E21.3 Hyperparathyroidism, unspecified
0.000 0.387 0.613
L42 Pityriasis rosea
0.000 0.387 0.613
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.389 0.611
D09.9 Carcinoma in situ, unspecified
0.000 0.389 0.611
D43.0 Brain, supratentorial
0.000 0.389 0.611
E13.3 With ophthalmic complications
0.000 0.390 0.610
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.394 0.606
C82.3 Follicular lymphoma grade IIIa
0.000 0.394 0.605
E28.9 Ovarian dysfunction, unspecified
0.000 0.395 0.605
E28.8 Other ovarian dysfunction
0.000 0.395 0.605
E28.1 Androgen excess
0.000 0.395 0.605
E28.0 Oestrogen excess
0.000 0.395 0.605
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.395 0.605
D09.1 Other and unspecified urinary organs
0.000 0.396 0.604
Q61.9 Cystic kidney disease, unspecified
0.000 0.399 0.601
E24.8 Other Cushing's syndrome
0.000 0.401 0.599
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.401 0.599
E24.3 Ectopic ACTH syndrome
0.000 0.401 0.599
E24.1 Nelson's syndrome
0.000 0.401 0.599
Q83 Congenital malformations of breast
0.000 0.401 0.599
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.402 0.598
E88.8 Other specified metabolic disorders
0.000 0.403 0.597
C74 Malignant neoplasm of adrenal gland
0.000 0.403 0.597
D09.7 Carcinoma in situ of other specified sites
0.000 0.404 0.596
D09.3 Thyroid and other endocrine glands
0.000 0.404 0.596
D09.2 Eye
0.000 0.404 0.596
E83.1 Disorders of iron metabolism
0.594 0.406 0.001
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.408 0.592
C91.7 Other lymphoid leukaemia
0.000 0.408 0.592
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.408 0.592
C91.3 Prolymphocytic leukaemia
0.000 0.408 0.592
C91.2 Subacute lymphocytic leukaemia
0.000 0.408 0.592
L40.0 Psoriasis vulgaris
0.000 0.412 0.588
M07.38 Other psoriatic arthropathies (Other)
0.000 0.412 0.588
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.412 0.588
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.412 0.588
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.412 0.588
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.413 0.587
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.414 0.586
E85 Amyloidosis
0.000 0.414 0.585
E06.3 Autoimmune thyroiditis
0.000 0.415 0.585
E13.9 Without complications
0.000 0.418 0.582
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.419 0.581
D00.1 Oesophagus
0.000 0.419 0.581
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.422 0.578
E21.4 Other specified disorders of parathyroid gland
0.000 0.422 0.578
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.422 0.578
C83.5 Lymphoblastic (diffuse)
0.000 0.422 0.578
D43.2 Brain, unspecified
0.000 0.425 0.575
H35.3 Degeneration of macula and posterior pole
0.000 0.427 0.573
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.427 0.573
E26.9 Hyperaldosteronism, unspecified
0.000 0.427 0.572
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.429 0.571
D03.5 Melanoma in situ of trunk
0.000 0.431 0.569
D06.9 Cervix, unspecified
0.000 0.431 0.569
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.431 0.569
H83.3 Noise effects on inner ear
0.000 0.431 0.569
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.432 0.568
C88.7 Other malignant immunoproliferative diseases
0.000 0.432 0.568
C88.3 Immunoproliferative small intestinal disease
0.000 0.432 0.568
C88.2 Gamma heavy chain disease
0.000 0.432 0.568
C88.1 Alpha heavy chain disease
0.000 0.432 0.568
E73 Lactose intolerance
0.000 0.432 0.567
C91.4 Hairy-cell leukaemia
0.000 0.436 0.564
Q51 Congenital malformations of uterus and cervix
0.000 0.437 0.563
H83.9 Disease of inner ear, unspecified
0.000 0.438 0.562
E13.8 With unspecified complications
0.000 0.439 0.561
E13.7 With multiple complications
0.000 0.439 0.561
E13.6 With other specified complications
0.000 0.439 0.561
E13.5 With peripheral circulatory complications
0.000 0.439 0.561
E13.4 With neurological complications
0.000 0.439 0.561
E13.2 With renal complications
0.000 0.439 0.561
E13.1 With ketoacidosis
0.000 0.439 0.561
E13.0 With coma
0.000 0.439 0.561
Q85.0 Neurofibromatosis (nonmalignant)
0.000 0.439 0.561
Q53 Undescended testicle
0.000 0.440 0.560
H30.9 Chorioretinal inflammation, unspecified
0.000 0.442 0.558
E67 Other hyperalimentation
0.000 0.443 0.557
E68 Sequelae of hyperalimentation
0.000 0.443 0.557
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.445 0.555
H35.1 Retinopathy of prematurity
0.000 0.445 0.554
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.446 0.554
G36.9 Acute disseminated demyelination, unspecified
0.553 0.446 0.000
G36.8 Other specified acute disseminated demyelination
0.553 0.446 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.553 0.446 0.000
E21.2 Other hyperparathyroidism
0.000 0.447 0.553
C12 Malignant neoplasm of pyriform sinus
0.000 0.453 0.547
C81 Hodgkin's disease
0.000 0.453 0.547
E11.1 With ketoacidosis
0.000 0.454 0.546
E78.8 Other disorders of lipoprotein metabolism
0.000 0.454 0.546
E24.9 Cushing's syndrome, unspecified
0.000 0.454 0.546
E22.1 Hyperprolactinaemia
0.000 0.456 0.544
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.000 0.459 0.541
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.000 0.459 0.541
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.461 0.539
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.461 0.539
E79.1 Lesch-Nyhan syndrome
0.000 0.461 0.539
Q61.5 Medullary cystic kidney
0.000 0.464 0.536
E72 Other disorders of amino-acid metabolism
0.000 0.465 0.535
H50 Other strabismus
0.000 0.472 0.528
L43.8 Other lichen planus
0.000 0.473 0.527
L57.4 Cutis laxa senilis
0.000 0.474 0.526
D47.2 Monoclonal gammopathy
0.000 0.475 0.525
Q52 Other congenital malformations of female genitalia
0.000 0.475 0.524
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.000 0.477 0.523
Q84 Other congenital malformations of integument
0.000 0.477 0.523
Q81 Epidermolysis bullosa
0.000 0.477 0.523
Q80 Congenital ichthyosis
0.000 0.477 0.523
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.477 0.523
E46 Unspecified protein-energy malnutrition
0.000 0.478 0.522
E88.9 Metabolic disorder, unspecified
0.000 0.478 0.521
H43-H45 Disorders of vitreous body and globe
0.000 0.479 0.521
E70.3 Albinism
0.000 0.480 0.519
H35.5 Hereditary retinal dystrophy
0.000 0.482 0.518
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.482 0.518
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.483 0.517
E45 Retarded development following protein-energy malnutrition
0.000 0.483 0.517
E43 Unspecified severe protein-energy malnutrition
0.000 0.483 0.517
E42 Marasmic kwashiorkor
0.000 0.483 0.517
E41 Nutritional marasmus
0.000 0.483 0.517
E40 Kwashiorkor
0.000 0.483 0.517
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.484 0.516
D00.2 Stomach
0.000 0.484 0.516
E07 Other disorders of thyroid
0.000 0.484 0.516
Q55 Other congenital malformations of male genital organs
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
Q30-Q34 Congenital malformations of the respiratory system
0.000 0.488 0.512
E88.3 Tumour lysis syndrome
0.000 0.488 0.512
Q85.1 Tuberous sclerosis
0.000 0.488 0.512
E30.9 Disorder of puberty, unspecified
0.000 0.488 0.512
E30.8 Other disorders of puberty
0.000 0.488 0.512
E30.1 Precocious puberty
0.000 0.488 0.512
E30.0 Delayed puberty
0.000 0.488 0.512
E31.9 Polyglandular dysfunction, unspecified
0.000 0.488 0.512
E31.8 Other polyglandular dysfunction
0.000 0.488 0.512
E31.1 Polyglandular hyperfunction
0.000 0.488 0.512
E31.0 Autoimmune polyglandular failure
0.000 0.488 0.512
E32.9 Disease of thymus, unspecified
0.000 0.488 0.512
E32.8 Other diseases of thymus
0.000 0.488 0.512
E32.1 Abscess of thymus
0.000 0.488 0.512
E32.0 Persistent hyperplasia of thymus
0.000 0.488 0.512
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.488 0.512
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.488 0.512
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.488 0.512
C43.8 Overlapping malignant melanoma of skin
0.000 0.488 0.512
C43.0 Malignant melanoma of lip
0.000 0.488 0.512
E26.8 Other hyperaldosteronism
0.000 0.488 0.511
E26.1 Secondary hyperaldosteronism
0.000 0.488 0.511
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.488 0.512
Q83.8 Other congenital malformations of breast
0.000 0.489 0.511
E78.3 Hyperchylomicronaemia
0.000 0.489 0.511
Q51.2 Other doubling of uterus
0.000 0.489 0.511
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.491 0.509
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.492 0.508
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.493 0.507
H50.0 Convergent concomitant strabismus
0.000 0.493 0.507
H83.2 Labyrinthine dysfunction
0.000 0.494 0.506
H83.1 Labyrinthine fistula
0.000 0.494 0.506
Q00-Q07 Congenital malformations of the nervous system
0.000 0.495 0.505
D06.7 Other parts of cervix
0.000 0.496 0.504
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.498 0.502
Q61.4 Renal dysplasia
0.000 0.498 0.502
H82 Vertiginous syndromes in diseases classified elsewhere
0.000 0.499 0.501
D01.0 Colon
0.000 0.500 0.500
Q35-Q37 Cleft lip and cleft palate
0.000 0.500 0.500
H35.4 Peripheral retinal degeneration
0.000 0.501 0.499
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.504 0.496
Q61.8 Other cystic kidney diseases
0.000 0.504 0.495
Q61.1 Polycystic kidney, infantile type
0.000 0.504 0.495
E88.2 Lipomatosis, not elsewhere classified
0.000 0.505 0.495
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.506 0.494
C96.8 Histiocytic sarcoma
0.000 0.506 0.494
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.506 0.494
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.506 0.494
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.506 0.494
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.506 0.494
C96.3 True histiocytic lymphoma
0.000 0.506 0.494
C96.2 Malignant mast cell tumour
0.000 0.506 0.494
C96.1 Malignant histiocytosis
0.000 0.506 0.494
C96.0 Letterer-Siwe disease
0.000 0.506 0.494
L43.3 Subacute (active) lichen planus
0.000 0.506 0.493
L43.2 Lichenoid drug reaction
0.000 0.506 0.493
L43.1 Bullous lichen planus
0.000 0.506 0.493
L43.0 Hypertrophic lichen planus
0.000 0.506 0.493
L12 Pemphigoid
0.000 0.507 0.493
D06.1 Exocervix
0.000 0.507 0.493
Q89 Other congenital malformations, not elsewhere classified
0.000 0.507 0.492
H60-H62 Diseases of external ear
0.000 0.508 0.492
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.509 0.491
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.509 0.491
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.510 0.490
Q56 Indeterminate sex and pseudohermaphroditism
0.000 0.510 0.489
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.511 0.489
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.511 0.489
E70.2 Disorders of tyrosine metabolism
0.000 0.511 0.489
E70.1 Other hyperphenylalaninaemias
0.000 0.511 0.489
E70.0 Classical phenylketonuria
0.000 0.511 0.489
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.511 0.489
E22.8 Other hyperfunction of pituitary gland
0.000 0.511 0.489
D43.4 Spinal cord
0.000 0.514 0.486
E06.4 Drug-induced thyroiditis
0.000 0.515 0.485
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.515 0.485
E06.0 Acute thyroiditis
0.000 0.515 0.485
Q64 Other congenital malformations of urinary system
0.000 0.515 0.484
C11 Malignant neoplasm of nasopharynx
0.000 0.516 0.484
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.516 0.484
L40.8 Other psoriasis
0.001 0.518 0.482
D00.0 Lip, oral cavity and pharynx
0.000 0.519 0.480
E25.9 Adrenogenital disorder, unspecified
0.000 0.520 0.480
E25.8 Other adrenogenital disorders
0.000 0.520 0.480
Chapter XXII Codes for special purposes
0.000 0.520 0.480
L44.9 Papulosquamous disorder, unspecified
0.000 0.520 0.480
L44.8 Other specified papulosquamous disorders
0.000 0.520 0.480
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.520 0.480
L44.3 Lichen ruber moniliformis
0.000 0.520 0.480
L44.2 Lichen striatus
0.000 0.520 0.480
L44.1 Lichen nitidus
0.000 0.520 0.480
L44.0 Pityriasis rubra pilaris
0.000 0.520 0.480
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.520 0.480
C94.7 Other specified leukaemias
0.000 0.522 0.478
C94.5 Acute myelofibrosis
0.000 0.522 0.478
C94.4 Acute panmyelosis
0.000 0.522 0.478
C94.3 Mast cell leukaemia
0.000 0.522 0.478

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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