TreeWAS – Variant ID: rs2621412

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.006	0.994
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.010	0.990
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.012	0.988
E00-E07 Disorders of thyroid gland	0.000	0.013	0.987
E05.9 Thyrotoxicosis, unspecified	0.000	0.018	0.982
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.080	0.920
C44.2 Skin of ear and external auricular canal	0.844	0.156	0.000
C44 Other malignant neoplasms of skin	0.843	0.157	0.000
E07 Other disorders of thyroid	0.000	0.160	0.840
L40.4 Guttate psoriasis	0.839	0.161	0.000
C44.3 Skin of other and unspecified parts of face	0.820	0.180	0.000
L40.1 Generalised pustular psoriasis	0.812	0.188	0.000
L40.0 Psoriasis vulgaris	0.811	0.189	0.000
C44.4 Skin of scalp and neck	0.803	0.197	0.000
J45 Asthma	0.000	0.216	0.784
C44.7 Skin of lower limb, including hip	0.780	0.220	0.000
C44.5 Skin of trunk	0.753	0.247	0.000
L40.8 Other psoriasis	0.734	0.266	0.000
K90 Intestinal malabsorption	0.000	0.271	0.729
J45.0 Predominantly allergic asthma	0.000	0.281	0.719
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.287	0.713
E03.4 Atrophy of thyroid (acquired)	0.000	0.287	0.713
E03.3 Postinfectious hypothyroidism	0.000	0.287	0.713
E05.5 Thyroid crisis or storm	0.000	0.290	0.709
E05.4 Thyrotoxicosis factitia	0.000	0.290	0.709
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.290	0.709
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.290	0.709
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.292	0.708
E00 Congenital iodine-deficiency syndrome	0.000	0.292	0.708
L40.3 Pustulosis palmaris et plantaris	0.700	0.300	0.000
E07.8 Other specified disorders of thyroid	0.000	0.303	0.697
C44.0 Skin of lip	0.677	0.323	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.323	0.677
E07.9 Disorder of thyroid, unspecified	0.000	0.334	0.666
E03.1 Congenital hypothyroidism without goitre	0.000	0.341	0.659
J45.1 Nonallergic asthma	0.000	0.367	0.633
E05.8 Other thyrotoxicosis	0.000	0.378	0.621
E03.8 Other specified hypothyroidism	0.000	0.389	0.611
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.396	0.604
C44.8 Overlapping lesion of skin	0.604	0.396	0.000
E07.1 Dyshormogenetic goitre	0.000	0.397	0.603
E07.0 Hypersecretion of calcitonin	0.000	0.397	0.603
K90.8 Other intestinal malabsorption	0.000	0.407	0.593
I25.8 Other forms of chronic ischaemic heart disease	0.588	0.412	0.000
I25 Chronic ischaemic heart disease	0.585	0.415	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.584	0.416	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.419	0.581
C44.9 Malignant neoplasm of skin, unspecified	0.572	0.428	0.000
J45.8 Mixed asthma	0.000	0.438	0.562
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.440	0.559
C44.1 Skin of eyelid, including canthus	0.548	0.452	0.000
I20-I25 Ischaemic heart diseases	0.532	0.468	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.477	0.522
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.477	0.522
K90.1 Tropical sprue	0.000	0.477	0.522
L40-L45 Papulosquamous disorders	0.516	0.484	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.492	0.507
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.492	0.507
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.492	0.507
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.492	0.507
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.492	0.507
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.492	0.507
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.492	0.507
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.492	0.507
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.503	0.497
I25.2 Old myocardial infarction	0.489	0.511	0.000
I22 Subsequent myocardial infarction	0.485	0.515	0.000
I24 Other acute ischaemic heart diseases	0.471	0.529	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.471	0.529	0.000
I25.3 Aneurysm of heart	0.463	0.537	0.000
I21 Acute myocardial infarction	0.449	0.551	0.000
I23 Certain current complications following acute myocardial infarction	0.443	0.557	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.443	0.557	0.000
I24.8 Other forms of acute ischaemic heart disease	0.432	0.568	0.000
I25.6 Silent myocardial ischaemia	0.420	0.580	0.000
L43 Lichen planus	0.399	0.601	0.000
L41 Parapsoriasis	0.393	0.607	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.392	0.608	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.388	0.612	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.387	0.613	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.382	0.618	0.000
I22.8 Subsequent myocardial infarction of other sites	0.378	0.622	0.000
L44 Other papulosquamous disorders	0.370	0.630	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.370	0.630	0.000
L42 Pityriasis rosea	0.356	0.644	0.000
M07.3 Other psoriatic arthropathies	0.349	0.651	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.346	0.654	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.343	0.657	0.000
E06 Thyroiditis	0.001	0.662	0.338
I24.1 Dressler's syndrome	0.333	0.667	0.000
L43.9 Lichen planus, unspecified	0.326	0.674	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.322	0.678	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.318	0.682	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.318	0.682	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.318	0.682	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.318	0.682	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.318	0.682	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.318	0.682	0.000
I25.4 Coronary artery aneurysm	0.314	0.686	0.000
I23.8 Other current complications following acute myocardial infarction	0.311	0.688	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.310	0.690	0.000
I25.1 Atherosclerotic heart disease	0.308	0.692	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.306	0.694	0.000
L41.1 Pityriasis lichenoides chronica	0.305	0.694	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.305	0.695	0.000
C44.6 Skin of upper limb, including shoulder	0.288	0.712	0.000
L43.3 Subacute (active) lichen planus	0.286	0.714	0.000
L43.2 Lichenoid drug reaction	0.286	0.714	0.000
L43.1 Bullous lichen planus	0.286	0.714	0.000
L43.0 Hypertrophic lichen planus	0.286	0.714	0.000
L41.9 Parapsoriasis, unspecified	0.282	0.718	0.000
L41.8 Other parapsoriasis	0.282	0.718	0.000
L41.5 Retiform parapsoriasis	0.282	0.718	0.000
L41.4 Large plaque parapsoriasis	0.282	0.718	0.000
L41.3 Small plaque parapsoriasis	0.282	0.718	0.000
L41.2 Lymphomatoid papulosis	0.282	0.718	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.282	0.718	0.000
I20 Angina pectoris	0.282	0.718	0.000
I25.5 Ischaemic cardiomyopathy	0.282	0.718	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.270	0.730	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.269	0.731	0.000
L43.8 Other lichen planus	0.269	0.731	0.000
L44.9 Papulosquamous disorder, unspecified	0.265	0.734	0.000
L44.8 Other specified papulosquamous disorders	0.265	0.734	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.265	0.734	0.000
L44.3 Lichen ruber moniliformis	0.265	0.734	0.000
L44.2 Lichen striatus	0.265	0.734	0.000
L44.1 Lichen nitidus	0.265	0.734	0.000
L44.0 Pityriasis rubra pilaris	0.265	0.734	0.000
M07.38 Other psoriatic arthropathies (Other)	0.250	0.750	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.250	0.750	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.250	0.750	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.249	0.751	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.249	0.751	0.000
I20.0 Unstable angina	0.244	0.756	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.243	0.757	0.000
E06.4 Drug-induced thyroiditis	0.001	0.757	0.242
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.757	0.242
E06.1 Subacute thyroiditis	0.001	0.757	0.242
E06.0 Acute thyroiditis	0.001	0.757	0.242
E06.5 Other chronic thyroiditis	0.001	0.777	0.222
I22.9 Subsequent myocardial infarction of unspecified site	0.221	0.778	0.000
I20.1 Angina pectoris with documented spasm	0.214	0.786	0.000
I21.4 Acute subendocardial myocardial infarction	0.199	0.801	0.000
E06.9 Thyroiditis, unspecified	0.001	0.820	0.179
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.179	0.821	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.167	0.833	0.000
M07 Psoriatic and enteropathic arthropathies	0.165	0.835	0.000
I21.9 Acute myocardial infarction, unspecified	0.165	0.835	0.000
C82.0 Small cleaved cell, follicular	0.164	0.836	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.157	0.843	0.000
T43.2 Other and unspecified antidepressants	0.147	0.853	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.146	0.854	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.141	0.859	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.140	0.860	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.140	0.860	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.139	0.861	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.139	0.861	0.000
I20.9 Angina pectoris, unspecified	0.139	0.861	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.137	0.863	0.000
T42.4 Benzodiazepines	0.136	0.864	0.000
C82.3 Follicular lymphoma grade IIIa	0.131	0.869	0.000
C82.2 Large cell, follicular	0.128	0.872	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.126	0.874	0.000
C82.6 Cutaneous follicle centre lymphoma	0.120	0.880	0.000
C82.5 Diffuse follicle centre lymphoma	0.120	0.880	0.000
C82.4 Follicular lymphoma grade IIIb	0.120	0.880	0.000
M07.6 Other enteropathic arthropathies	0.118	0.881	0.000
M07.5 Arthropathy in ulcerative colitis	0.118	0.881	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.118	0.881	0.000
M07.2 Psoriatic spondylitis	0.118	0.881	0.000
M07.1 Arthritis mutilans	0.118	0.881	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.118	0.881	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.117	0.883	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.114	0.886	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.114	0.886	0.000
T42.0 Hydantoin derivatives	0.113	0.887	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.113	0.887	0.000
T50.4 Drugs affecting uric acid metabolism	0.111	0.889	0.000
T42.3 Barbiturates	0.111	0.889	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.891	0.109
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.109	0.891	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.108	0.892	0.000
E06.3 Autoimmune thyroiditis	0.001	0.894	0.106
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.105	0.895	0.000
T43.9 Psychotropic drug, unspecified	0.105	0.895	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.105	0.895	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.104	0.896	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.898	0.102
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.102	0.898	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.898	0.102
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.101	0.899	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.101	0.899	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.100	0.900	0.000
T42.2 Succinimides and oxazolidinediones	0.100	0.900	0.000
T50.7 Analeptics and opioid receptor antagonists	0.100	0.900	0.000
T50.5 Appetite depressants	0.100	0.900	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.100	0.900	0.000
T50.1 Loop [high-ceiling] diuretics	0.100	0.900	0.000
T50.0 Mineralocorticoids and their antagonists	0.100	0.900	0.000
G03 Meningitis due to other and unspecified causes	0.000	0.903	0.097
N85.8 Other specified noninflammatory disorders of uterus	0.097	0.903	0.000
T36 Poisoning by systemic antibiotics	0.097	0.903	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.097	0.903	0.000
T42.1 Iminostilbenes	0.096	0.904	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.904	0.096
T50.8 Diagnostic agents	0.095	0.905	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.095	0.905	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.905	0.095
G00 Bacterial meningitis, not elsewhere classified	0.000	0.905	0.095
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.093	0.907	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.093	0.907	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.092	0.908	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.909	0.091
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.910	0.090
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.910	0.090
G03.9 Meningitis, unspecified	0.000	0.911	0.089
T43.6 Psychostimulants with abuse potential	0.087	0.912	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.085	0.915	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.085	0.915	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.085	0.915	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.085	0.915	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.085	0.915	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.085	0.915	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.085	0.915	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.085	0.915	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.085	0.915	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.085	0.915	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.085	0.915	0.000
M07.18 Arthritis mutilans (Other)	0.085	0.915	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.085	0.915	0.000
M07.16 Arthritis mutilans (Lower leg)	0.085	0.915	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.085	0.915	0.000
M07.14 Arthritis mutilans (Hand)	0.085	0.915	0.000
M07.13 Arthritis mutilans (Forearm)	0.085	0.915	0.000
M07.12 Arthritis mutilans (Upper arm)	0.085	0.915	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.085	0.915	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.085	0.915	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.085	0.915	0.000
M07.28 Psoriatic spondylitis (Other)	0.085	0.915	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.085	0.915	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.085	0.915	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.085	0.915	0.000
M07.24 Psoriatic spondylitis (Hand)	0.085	0.915	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.085	0.915	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.085	0.915	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.085	0.915	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.085	0.915	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.085	0.915	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.085	0.915	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.085	0.915	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.085	0.915	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.085	0.915	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.085	0.915	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.085	0.915	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.085	0.915	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.085	0.915	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.085	0.915	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.085	0.915	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.085	0.915	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.085	0.915	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.085	0.915	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.085	0.915	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.085	0.915	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.085	0.915	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.085	0.915	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.085	0.915	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.085	0.915	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.085	0.915	0.000
M07.68 Other enteropathic arthropathies (Other)	0.085	0.915	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.085	0.915	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.085	0.915	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.085	0.915	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.085	0.915	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.085	0.915	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.085	0.915	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.085	0.915	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.085	0.915	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.085	0.915	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.082	0.918	0.000
T37.5 Antiviral drugs	0.082	0.918	0.000
T37.4 Anthelminthics	0.082	0.918	0.000
T37.3 Other antiprotozoal drugs	0.082	0.918	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.082	0.918	0.000
T37.1 Antimycobacterial drugs	0.082	0.918	0.000
T37.0 Sulphonamides	0.082	0.918	0.000
G00.9 Bacterial meningitis, unspecified	0.000	0.918	0.082
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.081	0.919	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.081	0.919	0.000
T48.5 Anti-common-cold drugs	0.081	0.919	0.000
T48.4 Expectorants	0.081	0.919	0.000
T48.3 Antitussives	0.081	0.919	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.081	0.919	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.081	0.919	0.000
T48.0 Oxytocic drugs	0.081	0.919	0.000
G00.1 Pneumococcal meningitis	0.000	0.919	0.080
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.079	0.921	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.921	0.078
T47.1 Other antacids and anti-gastric-secretion drugs	0.078	0.921	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.078	0.922	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.078	0.922	0.000
T36.3 Macrolides	0.078	0.922	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.923	0.077
G06.1 Intraspinal abscess and granuloma	0.000	0.923	0.077
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.924	0.076
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.924	0.076
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.076	0.924	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.076	0.924	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.076	0.924	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.076	0.924	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.076	0.924	0.000
T44.0 Anticholinesterase agents	0.076	0.924	0.000
T47.2 Stimulant laxatives	0.075	0.925	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.075	0.925	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.075	0.925	0.000
T47.7 Emetics	0.075	0.925	0.000
T47.6 Antidiarrhoeal drugs	0.075	0.925	0.000
T47.5 Digestants	0.075	0.925	0.000
T47.4 Other laxatives	0.075	0.925	0.000
T47.3 Saline and osmotic laxatives	0.075	0.925	0.000
T47.0 Histamine H(2)-receptor antagonists	0.075	0.925	0.000
W19.9 Unspecified place	0.000	0.926	0.074
T38.1 Thyroid hormones and substitutes	0.074	0.926	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.927	0.073
G04.1 Tropical spastic paraplegia	0.000	0.927	0.073
G04.0 Acute disseminated encephalitis	0.000	0.927	0.073
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.927	0.073
T41.5 Therapeutic gases	0.072	0.928	0.000
T41.4 Anaesthetic, unspecified	0.072	0.928	0.000
T41.3 Local anaesthetics	0.072	0.928	0.000
T41.2 Other and unspecified general anaesthetics	0.072	0.928	0.000
T41.1 Intravenous anaesthetics	0.072	0.928	0.000
T41.0 Inhaled anaesthetics	0.072	0.928	0.000
T49.9 Topical agent, unspecified	0.072	0.928	0.000
T49.8 Other topical agents	0.072	0.928	0.000
T49.7 Dental drugs, topically applied	0.072	0.928	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.072	0.928	0.000
T49.5 Ophthalmological drugs and preparations	0.072	0.928	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.072	0.928	0.000
T49.3 Emollients, demulcents and protectants	0.072	0.928	0.000
T49.2 Local astringents and local detergents	0.072	0.928	0.000
T49.1 Antipruritics	0.072	0.928	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.072	0.928	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.928	0.072
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.928	0.072
T45.0 Antiallergic and antiemetic drugs	0.072	0.928	0.000
G06.2 Extradural and subdural abscess, unspecified	0.000	0.928	0.071
G03.8 Meningitis due to other specified causes	0.000	0.930	0.070
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.930	0.070
G03.1 Chronic meningitis	0.000	0.930	0.070
G03.0 Nonpyogenic meningitis	0.000	0.930	0.070
T36.9 Systemic antibiotic, unspecified	0.069	0.930	0.000
T36.8 Other systemic antibiotics	0.069	0.930	0.000
T36.7 Antifungal antibiotics, systemically used	0.069	0.930	0.000
T36.6 Rifamycins	0.069	0.930	0.000
T36.5 Aminoglycosides	0.069	0.930	0.000
T36.4 Tetracyclines	0.069	0.930	0.000
T36.2 Chloramphenicol group	0.069	0.930	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.069	0.930	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.069	0.931	0.000
E10.1 With ketoacidosis	0.000	0.931	0.069
G00.3 Staphylococcal meningitis	0.000	0.932	0.068
G00.2 Streptococcal meningitis	0.000	0.932	0.068
G00.0 Haemophilus meningitis	0.000	0.932	0.068
E10.9 Without complications	0.000	0.932	0.068
E10-E14 Diabetes mellitus	0.000	0.933	0.067
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.067	0.933	0.000
T38.9 Other and unspecified hormone antagonists	0.067	0.933	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.067	0.933	0.000
T38.7 Androgens and anabolic congeners	0.067	0.933	0.000
T38.5 Other oestrogens and progestogens	0.067	0.933	0.000
T38.4 Oral contraceptives	0.067	0.933	0.000
T38.2 Antithyroid drugs	0.067	0.933	0.000
T38.0 Glucocorticoids and synthetic analogues	0.067	0.933	0.000
T45.5 Anticoagulants	0.067	0.933	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.066	0.934	0.000
T45.8 Other primarily systemic and haematological agents	0.066	0.934	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.066	0.934	0.000
T45.6 Fibrinolysis-affecting drugs	0.066	0.934	0.000
T45.4 Iron and its compounds	0.066	0.934	0.000
T45.3 Enzymes, not elsewhere classified	0.066	0.934	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.066	0.934	0.000
E10.8 With unspecified complications	0.000	0.935	0.065
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.935	0.065
G02.1 Meningitis in mycoses	0.000	0.935	0.065
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.935	0.065
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.935	0.065
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.935	0.065
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.064	0.936	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.063	0.937	0.000
G06.0 Intracranial abscess and granuloma	0.000	0.937	0.062
E10.2 With renal complications	0.000	0.939	0.061
E04 Other non-toxic goitre	0.001	0.940	0.059
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.060	0.940	0.000
E40-E46 Malnutrition	0.000	0.940	0.060
E10.0 With coma	0.000	0.941	0.059
L57.0 Actinic keratosis	0.059	0.941	0.000
G35 Multiple sclerosis	0.000	0.942	0.058
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.056	0.944	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.056	0.944	0.000
T46.7 Peripheral vasodilators	0.056	0.944	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.056	0.944	0.000
G00.8 Other bacterial meningitis	0.000	0.944	0.056
L57 Skin changes due to chronic exposure to nonionising radiation	0.054	0.946	0.000
E10.6 With other specified complications	0.000	0.946	0.054
E10.4 With neurological complications	0.000	0.946	0.054
T36.0 Penicillins	0.052	0.947	0.000
T45.2 Vitamins, not elsewhere classified	0.052	0.948	0.000
E10.7 With multiple complications	0.000	0.948	0.052
T46.5 Other antihypertensive drugs, not elsewhere classified	0.051	0.949	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.051	0.949	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.949	0.051
T46.1 Calcium-channel blockers	0.048	0.951	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.951	0.048
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.048	0.952	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.048	0.952	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.047	0.952	0.000
K90-K93 Other diseases of the digestive system	0.000	0.952	0.048
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.047	0.953	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.047	0.953	0.000
E14 Unspecified diabetes mellitus	0.000	0.954	0.046
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.954	0.046
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.955	0.045
T46.4 Angiotensin-converting-enzyme inhibitors	0.044	0.956	0.000
E04.8 Other specified non-toxic goitre	0.001	0.957	0.043
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.957	0.043
E45 Retarded development following protein-energy malnutrition	0.000	0.957	0.043
E43 Unspecified severe protein-energy malnutrition	0.000	0.957	0.043
E42 Marasmic kwashiorkor	0.000	0.957	0.043
E41 Nutritional marasmus	0.000	0.957	0.043
E40 Kwashiorkor	0.000	0.957	0.043
L57.5 Actinic granuloma	0.041	0.959	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.040	0.960	0.000
L57.3 Poikiloderma of Civatte	0.039	0.961	0.000
L57.2 Cutis rhomboidalis nuchae	0.039	0.961	0.000
L57.1 Actinic reticuloid	0.039	0.961	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.961	0.039
E65-E68 Obesity and other hyperalimentation	0.000	0.961	0.039
E14.2 Withrenal complications	0.000	0.962	0.038
E14.8 With unspecified complications	0.000	0.962	0.038
T40.1 Heroin	0.038	0.962	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.037	0.962	0.000
E10.5 With peripheral circulatory complications	0.000	0.963	0.037
L58 Radiodermatitis	0.037	0.963	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.037	0.963	0.000
L55 Sunburn	0.036	0.963	0.000
I20.8 Other forms of angina pectoris	0.036	0.964	0.000
L57.4 Cutis laxa senilis	0.035	0.965	0.000
T40.5 Cocaine	0.035	0.965	0.000
E12.9 Without complications	0.000	0.965	0.035
E12.8 With unspecified complications	0.000	0.965	0.035
E12.7 With multiple complications	0.000	0.965	0.035
E12.6 With other specified complications	0.000	0.965	0.035
E12.5 With peripheral circulatory complications	0.000	0.965	0.035
E12.4 With neurological complications	0.000	0.965	0.035
E12.3 With ophthalmic complications	0.000	0.965	0.035
E12.2 With renal complications	0.000	0.965	0.035
E12.1 With ketoacidosis	0.000	0.965	0.035
E12.0 With coma	0.000	0.965	0.035
E14.1 With ketoacidosis	0.000	0.965	0.035
E13 Other specified diabetes mellitus	0.000	0.965	0.034
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.966	0.034
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.034	0.966	0.000
T40.8 Lysergide [LSD]	0.034	0.966	0.000
T40.7 Cannabis (derivatives)	0.034	0.966	0.000
T40.3 Methadone	0.034	0.966	0.000
T40.0 Opium	0.034	0.966	0.000
E14.5 With peripheral circulatory complications	0.000	0.966	0.034
E14.7 With multiple complications	0.000	0.966	0.033
E14.0 With coma	0.000	0.966	0.033
M05-M14 Inflammatory polyarthropathies	0.033	0.967	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.967	0.033
G36 Other acute disseminated demyelination	0.000	0.967	0.033
E15 Nondiabetic hypoglycaemic coma	0.000	0.967	0.033
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.032	0.967	0.000
M05 Seropositive rheumatoid arthritis	0.032	0.968	0.000
E14.6 With other specified complications	0.000	0.968	0.032
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.968	0.032
E04.1 Non-toxic single thyroid nodule	0.000	0.969	0.031
M05.9 Seropositive rheumatoid arthritis, unspecified	0.031	0.969	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.969	0.031
E44.0 Moderate protein-energy malnutrition	0.000	0.969	0.031
E50-E64 Other nutritional deficiencies	0.000	0.969	0.031
E14.3 With ophthalmic complications	0.000	0.969	0.031
T43.0 Tricyclic and tetracyclic antidepressants	0.031	0.969	0.000
E14.4 With neurological complications	0.000	0.970	0.030
Chapter VI Diseases of the nervous system	0.000	0.970	0.030
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.029	0.971	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.972	0.028
G37.4 Subacute necrotising myelitis	0.000	0.972	0.028
G37.2 Central pontine myelinolysis	0.000	0.972	0.028
G37.1 Central demyelination of corpus callosum	0.000	0.972	0.028
G37.0 Diffuse sclerosis	0.000	0.972	0.028

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations