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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2647073
log Bayes Factor = 96.5928
Chromosome 6   position 32,574,014  (GRCh37) Explore rs2647073 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M20-M25 Other joint disorders
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
J47 Bronchiectasis
0.000 0.001 0.999
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
M35.0 Sicca syndrome [Sjogren]
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.008 0.992
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.009 0.991
G35 Multiple sclerosis
0.000 0.010 0.990
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.011 0.989
M34 Systemic sclerosis
0.000 0.011 0.989
L20-L30 Dermatitis and eczema
0.000 0.011 0.989
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.012 0.988
N48 Other disorders of penis
0.986 0.014 0.000
J20-J22 Other acute lower respiratory infections
0.000 0.015 0.985
N48.6 Balanitis xerotica obliterans
0.983 0.017 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.023 0.977
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.025 0.975
H02 Other disorders of eyelid
0.000 0.026 0.974
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.028 0.972
J22 Unspecified acute lower respiratory infection
0.000 0.030 0.970
H04 Disorders of lachrymal system
0.000 0.030 0.970
J44 Other chronic obstructive pulmonary disease
0.000 0.033 0.967
E10.4 With neurological complications
0.000 0.033 0.967
J80 Adult respiratory distress syndrome
0.000 0.034 0.966
J84 Other interstitial pulmonary diseases
0.000 0.042 0.958
H55-H59 Other disorders of eye and adnexa
0.000 0.042 0.958
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.043 0.957
H02.0 Entropion and trichiasis of eyelid
0.000 0.045 0.955
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.045 0.955
M34.9 Systemic sclerosis, unspecified
0.000 0.045 0.955
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.046 0.954
H02.1 Ectropion of eyelid
0.000 0.046 0.954
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.047 0.953
E27 Other disorders of adrenal gland
0.000 0.048 0.952
L40.0 Psoriasis vulgaris
0.946 0.054 0.000
J32 Chronic sinusitis
0.000 0.055 0.945
D50-D53 Nutritional anaemias
0.000 0.057 0.943
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.058 0.942
L30 Other dermatitis
0.000 0.059 0.941
D69 Purpura and other haemorrhagic conditions
0.000 0.061 0.939
E27.1 Primary adrenocortical insufficiency
0.000 0.064 0.936
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.066 0.934
D68 Other coagulation defects
0.000 0.068 0.932
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.069 0.931
E06 Thyroiditis
0.000 0.069 0.931
E10.5 With peripheral circulatory complications
0.000 0.071 0.929
N48.8 Other specified disorders of penis
0.929 0.071 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.072 0.928
N48.0 Leukoplakia of penis
0.926 0.074 0.000
H57 Other disorders of eye and adnexa
0.000 0.078 0.922
Chapter VI Diseases of the nervous system
0.000 0.079 0.921
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.081 0.919
E10.2 With renal complications
0.000 0.089 0.911
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.093 0.907
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.094 0.906
L29 Pruritus
0.000 0.098 0.902
E07 Other disorders of thyroid
0.000 0.101 0.899
M06.0 Seronegative rheumatoid arthritis
0.000 0.101 0.899
L81 Other disorders of pigmentation
0.000 0.102 0.898
L85 Other epidermal thickening
0.000 0.107 0.893
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.107 0.893
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.111 0.889
N48.9 Disorder of penis, unspecified
0.888 0.112 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.113 0.887
N48.4 Impotence of organic origin
0.887 0.113 0.000
L30.9 Dermatitis, unspecified
0.000 0.113 0.887
J33.8 Other polyp of sinus
0.000 0.113 0.886
H06.2 Dysthyroid exophthalmos
0.000 0.118 0.882
M34.1 CR(E)ST syndrome
0.000 0.123 0.877
N48.1 Balanoposthitis
0.875 0.125 0.000
D50 Iron deficiency anaemia
0.000 0.125 0.875
E06.3 Autoimmune thyroiditis
0.000 0.125 0.875
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.128 0.872
M06.3 Rheumatoid nodule
0.000 0.131 0.869
J81 Pulmonary oedema
0.000 0.133 0.867
H57.0 Anomalies of pupillary function
0.000 0.135 0.865
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.136 0.864
E28 Ovarian dysfunction
0.000 0.137 0.863
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.142 0.858
L81.4 Other melanin hyperpigmentation
0.000 0.143 0.857
M06.4 Inflammatory polyarthropathy
0.000 0.145 0.855
L57.0 Actinic keratosis
0.000 0.146 0.854
D68.8 Other specified coagulation defects
0.000 0.148 0.852
N40-N51 Diseases of male genital organs
0.850 0.150 0.000
J95-J99 Other diseases of the respiratory system
0.000 0.150 0.850
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.150 0.850
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.152 0.848
N47 Redundant prepuce, phimosis and paraphimosis
0.843 0.157 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.159 0.841
L29.0 Pruritus ani
0.000 0.160 0.840
L85.9 Epidermal thickening, unspecified
0.000 0.161 0.839
E23 Hypofunction and other disorders of pituitary gland
0.000 0.163 0.837
M34.8 Other forms of systemic sclerosis
0.000 0.167 0.833
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.169 0.831
J31.0 Chronic rhinitis
0.000 0.170 0.830
J32.9 Chronic sinusitis, unspecified
0.000 0.170 0.830
L94 Other localised connective tissue disorders
0.000 0.171 0.829
L83 Acanthosis nigricans
0.000 0.171 0.829
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.173 0.826
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.174 0.826
D68.9 Coagulation defect, unspecified
0.000 0.175 0.825
D50.8 Other iron deficiency anaemias
0.000 0.176 0.824
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.178 0.822
E07.9 Disorder of thyroid, unspecified
0.000 0.180 0.820
L93 Lupus erythematosus
0.000 0.182 0.818
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.184 0.816
D68.5 Primary Thrombophilia
0.000 0.184 0.816
J32.8 Other chronic sinusitis
0.000 0.184 0.816
L30.8 Other specified dermatitis
0.000 0.185 0.815
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.191 0.809
D52 Folate deficiency anaemia
0.000 0.193 0.807
N48.5 Ulcer of penis
0.807 0.193 0.000
L21 Seborrhoeic dermatitis
0.000 0.193 0.807
E29 Testicular dysfunction
0.000 0.194 0.806
H05 Disorders of orbit
0.000 0.197 0.803
E20 Hypoparathyroidism
0.000 0.200 0.800
J32.0 Chronic maxillary sinusitis
0.000 0.201 0.799
E04 Other non-toxic goitre
0.000 0.203 0.797
H16 Keratitis
0.000 0.205 0.795
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.208 0.792
D69.5 Secondary thrombocytopenia
0.000 0.209 0.791
M06.34 Rheumatoid nodule (Hand)
0.000 0.212 0.788
H55 Nystagmus and other irregular eye movements
0.000 0.212 0.788
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.212 0.788
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.214 0.786
H57.8 Other specified disorders of eye and adnexa
0.000 0.216 0.784
L40-L45 Papulosquamous disorders
0.511 0.216 0.273
D69.0 Allergic purpura
0.000 0.217 0.783
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.218 0.782
D60-D64 Aplastic and other anaemias
0.000 0.219 0.781
M32 Systemic lupus erythematosus
0.000 0.220 0.780
H01 Other inflammation of eyelid
0.000 0.225 0.775
E10.8 With unspecified complications
0.000 0.226 0.774
G37 Other demyelinating diseases of central nervous system
0.000 0.226 0.774
E05.8 Other thyrotoxicosis
0.000 0.229 0.770
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.231 0.769
E27.8 Other specified disorders of adrenal gland
0.000 0.239 0.761
H20 Iridocyclitis
0.000 0.241 0.759
G90-G99 Other disorders of the nervous system
0.000 0.242 0.758
N45 Orchitis and epididymitis
0.755 0.245 0.000
L28 Lichen simplex chronicus and prurigo
0.000 0.248 0.752
L40.1 Generalised pustular psoriasis
0.751 0.249 0.000
M35.7 Hypermobility syndrome
0.000 0.250 0.750
H04.8 Other disorders of lachrymal system
0.000 0.250 0.750
J84.8 Other specified interstitial pulmonary diseases
0.000 0.252 0.748
J20 Acute bronchitis
0.000 0.252 0.747
L80 Vitiligo
0.000 0.255 0.745
H57.9 Disorder of eye and adnexa, unspecified
0.000 0.255 0.745
N48.2 Other inflammatory disorders of penis
0.743 0.257 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.257 0.743
J21 Acute bronchiolitis
0.000 0.258 0.742
L25 Unspecified contact dermatitis
0.000 0.259 0.741
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.260 0.740
E14 Unspecified diabetes mellitus
0.000 0.261 0.739
L29.2 Pruritus vulvae
0.000 0.261 0.739
H02.6 Xanthelasma of eyelid
0.000 0.262 0.738
L20 Atopic dermatitis
0.000 0.264 0.736
H04.1 Other disorders of lachrymal gland
0.000 0.265 0.735
L08 Other local infections of skin and subcutaneous tissue
0.000 0.266 0.734
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.268 0.732
D68.0 Von Willebrand's disease
0.000 0.268 0.732
M60-M63 Disorders of muscles
0.000 0.268 0.732
H16.0 Corneal ulcer
0.000 0.269 0.731
E28.2 Polycystic ovarian syndrome
0.000 0.270 0.730
E04.2 Non-toxic multinodular goitre
0.000 0.273 0.727
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.273 0.727
E16 Other disorders of pancreatic internal secretion
0.000 0.273 0.727
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.273 0.727
D69.4 Other primary thrombocytopenia
0.000 0.274 0.726
L27 Dermatitis due to substances taken internally
0.000 0.274 0.726
E26 Hyperaldosteronism
0.000 0.277 0.723
M30 Polyarteritis nodosa and related conditions
0.000 0.279 0.721
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.280 0.720
M22 Disorders of patella
0.000 0.281 0.719
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.281 0.719
G91 Hydrocephalus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.8 Other specified systemic involvement of connective tissue
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M35.2 Behcet's disease
0.000 0.283 0.717
M35.1 Other overlap syndromes
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
L82 Seborrhoeic keratosis
0.000 0.287 0.713
D61 Other aplastic anaemias
0.000 0.287 0.713
L84 Corns and callosities
0.000 0.287 0.713
E28.3 Primary ovarian failure
0.000 0.288 0.712
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.289 0.711
L87 Transepidermal elimination disorders
0.000 0.289 0.711
L88 Pyoderma gangrenosum
0.000 0.289 0.711
L86 Keratoderma in diseases classified elsewhere
0.000 0.289 0.711
D52.9 Folate deficiency anaemia, unspecified
0.000 0.290 0.710
H04.9 Disorder of lachrymal system, unspecified
0.000 0.290 0.710
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.291 0.709
M34.0 Progressive systemic sclerosis
0.000 0.291 0.709
L24 Irritant contact dermatitis
0.000 0.291 0.709
L26 Exfoliative dermatitis
0.000 0.291 0.709
L22 Diaper [napkin] dermatitis
0.000 0.291 0.709
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.293 0.707
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.293 0.707
N48.3 Priapism
0.707 0.293 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.297 0.703
J00-J06 Acute upper respiratory infections
0.000 0.299 0.701
J32.4 Chronic pansinusitis
0.000 0.299 0.701
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.300 0.700
E32 Diseases of thymus
0.000 0.300 0.700
E31 Polyglandular dysfunction
0.000 0.300 0.700
E30 Disorders of puberty, not elsewhere classified
0.000 0.300 0.700
D67 Hereditary factor IX deficiency
0.000 0.301 0.699
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.301 0.699
E10.6 With other specified complications
0.000 0.302 0.698
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.302 0.698
H05.0 Acute inflammation of orbit
0.000 0.302 0.697
J32.1 Chronic frontal sinusitis
0.000 0.303 0.697
L58 Radiodermatitis
0.000 0.303 0.697
L55 Sunburn
0.000 0.303 0.697
J95.8 Other postprocedural respiratory disorders
0.000 0.303 0.697
E06.9 Thyroiditis, unspecified
0.000 0.304 0.696
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.696 0.304 0.000
H04.6 Other changes in lachrymal passages
0.000 0.305 0.695
H04.0 Dacryoadenitis
0.000 0.305 0.695
H53-H54 Visual disturbances and blindness
0.000 0.305 0.695
L93.0 Discoid lupus erythematosus
0.000 0.307 0.693
L57.4 Cutis laxa senilis
0.000 0.308 0.692
L94.0 Localised scleroderma [morphea]
0.000 0.308 0.692
E27.9 Disorder of adrenal gland, unspecified
0.000 0.309 0.691
H30 Chorioretinal inflammation
0.000 0.309 0.691
E23.2 Diabetes insipidus
0.000 0.310 0.690
M86-M90 Other osteopathies
0.000 0.311 0.689
M12 Other specific arthropathies
0.000 0.312 0.688
H04.4 Chronic inflammation of lachrymal passages
0.000 0.312 0.688
J84.0 Alveolar and parietoalveolar conditions
0.000 0.313 0.687
J31.2 Chronic pharyngitis
0.000 0.313 0.687
G36 Other acute disseminated demyelination
0.000 0.314 0.686
E03.8 Other specified hypothyroidism
0.000 0.314 0.686
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.315 0.684
L57.5 Actinic granuloma
0.000 0.315 0.684
L57.3 Poikiloderma of Civatte
0.000 0.315 0.684
L57.2 Cutis rhomboidalis nuchae
0.000 0.315 0.684
L57.1 Actinic reticuloid
0.000 0.315 0.684
E29.1 Testicular hypofunction
0.000 0.316 0.684
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.317 0.683
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.317 0.683
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.317 0.683
L98.1 Factitial dermatitis
0.000 0.317 0.683
E27.5 Adrenomedullary hyperfunction
0.000 0.318 0.682
E27.0 Other adrenocortical overactivity
0.000 0.318 0.682
H02.2 Lagophthalmos
0.000 0.319 0.680
L10-L14 Bullous disorders
0.000 0.322 0.678
J32.3 Chronic sphenoidal sinusitis
0.000 0.323 0.677
M00-M03 Infectious arthropathies
0.000 0.323 0.677
H02.5 Other disorders affecting eyelid function
0.000 0.323 0.677
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.323 0.677
L30.5 Pityriasis alba
0.000 0.325 0.675
L30.4 Erythema intertrigo
0.000 0.325 0.675
L30.2 Cutaneous autosensitisation
0.000 0.325 0.675
L30.1 Dyshidrosis [pompholyx]
0.000 0.325 0.675
L30.0 Nummular dermatitis
0.000 0.325 0.675
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.326 0.674
E20.9 Hypoparathyroidism, unspecified
0.000 0.326 0.674
D69.8 Other specified haemorrhagic conditions
0.000 0.326 0.673
D69.1 Qualitative platelet defects
0.000 0.326 0.673
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.326 0.673
H01.8 Other specified inflammation of eyelid
0.000 0.327 0.673
E16.2 Hypoglycaemia, unspecified
0.000 0.328 0.672
D68.6 Other Thrombophilia
0.000 0.331 0.669
D68.4 Acquired coagulation factor deficiency
0.000 0.332 0.668
E23.6 Other disorders of pituitary gland
0.000 0.332 0.668
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.333 0.667
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.333 0.667
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.333 0.667
E06.5 Other chronic thyroiditis
0.000 0.333 0.667
E06.4 Drug-induced thyroiditis
0.000 0.333 0.667
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.333 0.667
E06.1 Subacute thyroiditis
0.000 0.333 0.667
E06.0 Acute thyroiditis
0.000 0.333 0.667
E07.8 Other specified disorders of thyroid
0.000 0.333 0.667
G91.9 Hydrocephalus, unspecified
0.000 0.335 0.665
N44 Torsion of testis
0.664 0.336 0.000
D61.9 Aplastic anaemia, unspecified
0.000 0.336 0.664
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.337 0.663
L95.8 Other vasculitis limited to skin
0.000 0.338 0.662
D68.1 Hereditary factor XI deficiency
0.000 0.339 0.661
L40.8 Other psoriasis
0.660 0.340 0.000
J60-J70 Lung diseases due to external agents
0.000 0.344 0.656
L29.8 Other pruritus
0.000 0.344 0.656
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.345 0.655
D53 Other nutritional anaemias
0.000 0.347 0.653
J95.0 Tracheostomy malfunction
0.000 0.348 0.652
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.349 0.650
J31.1 Chronic nasopharyngitis
0.000 0.350 0.650
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.350 0.650
J37 Chronic laryngitis and laryngotracheitis
0.000 0.350 0.650
H05.2 Exophthalmic conditions
0.000 0.352 0.648
L98.5 Mucinosis of skin
0.000 0.352 0.648
E27.2 Addisonian crisis
0.000 0.352 0.648
L29.1 Pruritus scroti
0.000 0.353 0.647
H20.8 Other iridocyclitis
0.000 0.353 0.647
L95.9 Vasculitis limited to skin, unspecified
0.000 0.354 0.646
E07.1 Dyshormogenetic goitre
0.000 0.355 0.645
E07.0 Hypersecretion of calcitonin
0.000 0.355 0.645
E22 Hyperfunction of pituitary gland
0.000 0.355 0.645
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.356 0.644
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.356 0.644
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.356 0.644
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.356 0.644
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.356 0.644
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.356 0.644
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.356 0.644
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.356 0.644
L81.7 Pigmented purpuric dermatosis
0.000 0.356 0.644
L81.6 Other disorders of diminished melanin formation
0.000 0.356 0.644
L81.5 Leukoderma, not elsewhere classified
0.000 0.356 0.644
L81.3 Cafe au lait spots
0.000 0.356 0.644
L81.2 Freckles
0.000 0.356 0.644
L81.1 Chloasma
0.000 0.356 0.644
L81.0 Postinflammatory hyperpigmentation
0.000 0.356 0.644
L94.2 Calcinosis cutis
0.000 0.358 0.642
E14.3 With ophthalmic complications
0.000 0.359 0.641
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.641 0.359 0.000
L85.3 Xerosis cutis
0.000 0.359 0.641
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.359 0.641
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.359 0.641
L85.0 Acquired ichthyosis
0.000 0.359 0.641
D69.6 Thrombocytopenia, unspecified
0.000 0.360 0.640
G80 Infantile cerebral palsy
0.000 0.360 0.640
E04.0 Non-toxic diffuse goitre
0.000 0.362 0.638
M22.2 Patellofemoral disorders
0.000 0.363 0.637
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.363 0.637
M31 Other necrotising vasculopathies
0.000 0.367 0.633
E34 Other endocrine disorders
0.000 0.367 0.633
H16.9 Keratitis, unspecified
0.000 0.370 0.630
L23 Allergic contact dermatitis
0.000 0.371 0.629
D50.1 Sideropenic dysphagia
0.000 0.373 0.627
J00 Acute nasopharyngitis [common cold]
0.000 0.373 0.627
G91.1 Obstructive hydrocephalus
0.000 0.373 0.627
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.374 0.625
L81.8 Other specified disorders of pigmentation
0.000 0.376 0.624
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.377 0.623
M06.38 Rheumatoid nodule (Other)
0.000 0.377 0.623
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.377 0.623
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.377 0.623
M06.33 Rheumatoid nodule (Forearm)
0.000 0.377 0.623
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.377 0.623
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.377 0.623
N42 Other disorders of prostate
0.623 0.377 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.378 0.622
H31 Other disorders of choroid
0.000 0.380 0.620
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.380 0.620
E28.9 Ovarian dysfunction, unspecified
0.000 0.381 0.619
E28.8 Other ovarian dysfunction
0.000 0.381 0.619
E28.1 Androgen excess
0.000 0.381 0.619
E28.0 Oestrogen excess
0.000 0.381 0.619
E23.0 Hypopituitarism
0.000 0.384 0.616
G80.9 Infantile cerebral palsy, unspecified
0.000 0.385 0.615
H00 Hordeolum and chalazion
0.000 0.385 0.615
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.386 0.614
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.387 0.613
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.387 0.613
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.387 0.613
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.387 0.613
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.387 0.613
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.387 0.613
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.387 0.613
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.387 0.613
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.388 0.611
N51 Disorders of male genital organs in diseases classified elsewhere
0.610 0.390 0.000
J35 Chronic diseases of tonsils and adenoids
0.000 0.390 0.610
J96 Respiratory failure, not elsewhere classified
0.000 0.390 0.609
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.391 0.609
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.392 0.608
D62 Acute posthaemorrhagic anaemia
0.000 0.393 0.607
M11 Other crystal arthropathies
0.000 0.393 0.607
E40-E46 Malnutrition
0.000 0.396 0.604
E15 Nondiabetic hypoglycaemic coma
0.000 0.397 0.603
H20.9 Iridocyclitis, unspecified
0.000 0.398 0.602
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.399 0.601
L29.9 Pruritus, unspecified
0.000 0.399 0.601
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.399 0.600
H15 Disorders of sclera
0.000 0.400 0.600
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.400 0.600
E23.1 Drug-induced hypopituitarism
0.000 0.400 0.600
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.401 0.599
G90 Disorders of autonomic nervous system
0.000 0.401 0.599
E65-E68 Obesity and other hyperalimentation
0.000 0.403 0.597
E50-E64 Other nutritional deficiencies
0.000 0.404 0.596
H57.1 Ocular pain
0.000 0.404 0.596
H18 Other disorders of cornea
0.000 0.404 0.596
E23.7 Disorder of pituitary gland, unspecified
0.000 0.405 0.595
L94.8 Other specified localised connective tissue disorders
0.000 0.406 0.594
L94.6 Ainhum
0.000 0.406 0.594
L94.5 Poikiloderma vasculare atrophicans
0.000 0.406 0.594
L94.4 Gottron's papules
0.000 0.406 0.594
L94.3 Sclerodactyly
0.000 0.406 0.594
L94.1 Linear scleroderma
0.000 0.406 0.594
D69.2 Other nonthrombocytopenic purpura
0.000 0.406 0.594
J20.9 Acute bronchitis, unspecified
0.000 0.406 0.593
E25 Adrenogenital disorders
0.000 0.406 0.593
M33 Dermatopolymyositis
0.000 0.408 0.592
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.410 0.590
H53 Visual disturbances
0.000 0.410 0.590
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.410 0.590
L95.1 Erythema elevatum diutinum
0.000 0.410 0.590
L95.0 Livedoid vasculitis
0.000 0.410 0.590
D80-D89 Certain disorders involving the immune mechanism
0.000 0.412 0.588
M89 Other disorders of bone
0.000 0.412 0.588
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.412 0.588
L30.3 Infective dermatitis
0.000 0.413 0.587
L93.2 Other local lupus erythematosus
0.000 0.413 0.587
L93.1 Subacute cutaneous lupus erythematosus
0.000 0.413 0.587
L44 Other papulosquamous disorders
0.414 0.415 0.171
M14 Arthropathies in other diseases classified elsewhere
0.000 0.417 0.583
L28.1 Prurigo nodularis
0.000 0.417 0.583
D55-D59 Haemolytic anaemias
0.000 0.418 0.582
D52.8 Other folate deficiency anaemias
0.000 0.421 0.579
D52.1 Drug-induced folate deficiency anaemia
0.000 0.421 0.579
D52.0 Dietary folate deficiency anaemia
0.000 0.421 0.579
L21.8 Other seborrhoeic dermatitis
0.000 0.421 0.579
L21.1 Seborrhoeic infantile dermatitis
0.000 0.421 0.579
L21.0 Seborrhoea capitis
0.000 0.421 0.579
M45-M49 Spondylopathies
0.002 0.421 0.577

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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