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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2678912
log Bayes Factor = 7.34991
Chromosome 2   position 58,145,973  (GRCh37) Explore rs2678912 on Ensembl!
Variant rs2678912 is part of Cluster X0210

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z92 Personal history of medical treatment
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
E83 Disorders of mineral metabolism
0.988 0.012 0.000
Chapter VII Diseases of the eye and adnexa
0.983 0.017 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.982 0.018 0.000
E83.5 Disorders of calcium metabolism
0.968 0.032 0.000
Chapter VIII Diseases of the ear and mastoid process
0.964 0.036 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.964 0.036 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.959 0.041 0.000
Z80 Family history of malignant neoplasm
0.959 0.041 0.000
H65-H75 Diseases of middle ear and mastoid
0.956 0.044 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.953 0.047 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.953 0.047 0.000
Z90.5 Acquired absence of kidney
0.952 0.048 0.000
E20-E35 Disorders of other endocrine glands
0.941 0.059 0.000
Z83 Family history of other specific disorders
0.939 0.061 0.000
E87.5 Hyperkalaemia
0.937 0.063 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.936 0.064 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.934 0.066 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.932 0.068 0.000
Z42 Follow-up care involving plastic surgery
0.928 0.072 0.000
Z93 Artificial opening status
0.926 0.074 0.000
E40-E46 Malnutrition
0.917 0.083 0.000
H55-H59 Other disorders of eye and adnexa
0.917 0.083 0.000
S40-S49 Injuries to the shoulder and upper arm
0.916 0.084 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.912 0.088 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.912 0.088 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.903 0.097 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.902 0.098 0.000
H73 Other disorders of tympanic membrane
0.901 0.099 0.000
Z92.3 Personal history of irradiation
0.897 0.103 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.895 0.105 0.000
Z40 Prophylactic surgery
0.894 0.106 0.000
Z80.3 Family history of malignant neoplasm of breast
0.893 0.107 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.888 0.112 0.000
Chapter X Diseases of the respiratory system
0.884 0.116 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.883 0.117 0.000
H74 Other disorders of middle ear and mastoid
0.882 0.118 0.000
H04 Disorders of lachrymal system
0.882 0.118 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.881 0.119 0.000
Z93.2 Ileostomy status
0.878 0.122 0.000
E27 Other disorders of adrenal gland
0.878 0.122 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.877 0.123 0.000
E83.4 Disorders of magnesium metabolism
0.876 0.124 0.000
Z90.0 Acquired absence of part of head and neck
0.875 0.125 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.869 0.131 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.869 0.131 0.000
Z85 Personal history of malignant neoplasm
0.869 0.131 0.000
J60-J70 Lung diseases due to external agents
0.863 0.137 0.000
H73.8 Other specified disorders of tympanic membrane
0.862 0.138 0.000
E46 Unspecified protein-energy malnutrition
0.858 0.142 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.851 0.149 0.000
J09-J18 Influenza and pneumonia
0.851 0.149 0.000
H20 Iridocyclitis
0.849 0.151 0.000
E87.0 Hyperosmolality and hypernatraemia
0.848 0.152 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.847 0.153 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.846 0.154 0.000
T81 Complications of procedures, not elsewhere classified
0.846 0.154 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.844 0.156 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.843 0.157 0.000
Chapter XXII Codes for special purposes
0.842 0.158 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.841 0.159 0.000
S70-S79 Injuries to the hip and thigh
0.841 0.159 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.840 0.160 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.834 0.166 0.000
H55 Nystagmus and other irregular eye movements
0.834 0.166 0.000
Chapter I Certain infectious and parasitic diseases
0.833 0.167 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.831 0.169 0.000
J18 Pneumonia, organism unspecified
0.830 0.170 0.000
H30-H36 Disorders of choroid and retina
0.830 0.170 0.000
E88 Other metabolic disorders
0.828 0.172 0.000
V40-V49 Car occupant injured in transport accident
0.828 0.172 0.000
Y60.0 During surgical operation
0.827 0.173 0.000
E83.1 Disorders of iron metabolism
0.827 0.173 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.827 0.173 0.000
E50-E64 Other nutritional deficiencies
0.825 0.175 0.000
H16 Keratitis
0.823 0.177 0.000
Z83.3 Family history of diabetes mellitus
0.822 0.178 0.000
Z41 Procedures for purposes other than remedying health state
0.822 0.178 0.000
H04.2 Epiphora
0.821 0.179 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.821 0.179 0.000
J18.1 Lobar pneumonia, unspecified
0.820 0.180 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.819 0.181 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.817 0.183 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.816 0.184 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.814 0.186 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.813 0.187 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.813 0.187 0.000
Z57 Occupational exposure to risk-factors
0.813 0.187 0.000
Z97 Presence of other devices
0.812 0.188 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.812 0.188 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.809 0.191 0.000
S40 Superficial injury of shoulder and upper arm
0.807 0.193 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.806 0.194 0.000
Chapter II Neoplasms
0.806 0.194 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.805 0.195 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.792 0.208 0.000
W00-W19 Falls
0.791 0.209 0.000
Z90.8 Acquired absence of other organs
0.789 0.211 0.000
H10-H13 Disorders of conjunctiva
0.789 0.211 0.000
H66 Suppurative and unspecified otitis media
0.788 0.212 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.788 0.212 0.000
S41 Open wound of shoulder and upper arm
0.787 0.213 0.000
E27.1 Primary adrenocortical insufficiency
0.786 0.214 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.786 0.214 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.784 0.216 0.000
T79-T79 Certain early complications of trauma
0.783 0.217 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.782 0.218 0.000
S10-S19 Injuries to the neck
0.782 0.218 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.782 0.218 0.000
S60-S69 Injuries to the wrist and hand
0.782 0.218 0.000
B95-B98 Bacterial, viral and other infectious agents
0.780 0.220 0.000
H01 Other inflammation of eyelid
0.780 0.220 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.779 0.221 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.777 0.223 0.000
Z92.8 Personal history of other medical treatment
0.775 0.225 0.000
O16 Unspecified maternal hypertension
0.775 0.225 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.773 0.227 0.000
Y43 Primarily systemic agents
0.769 0.231 0.000
Z97.4 Presence of external hearing-aid
0.769 0.231 0.000
H65 Nonsuppurative otitis media
0.767 0.233 0.000
H71 Cholesteatoma of middle ear
0.767 0.233 0.000
H36 Retinal disorders in diseases classified elsewhere
0.765 0.235 0.000
Z90.3 Acquired absence of part of stomach
0.763 0.237 0.000
Z83.7 Family history of diseases of the digestive system
0.763 0.237 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.761 0.239 0.000
E89.0 Postprocedural hypothyroidism
0.761 0.239 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.760 0.240 0.000
T86 Failure and rejection of transplanted organs and tissues
0.757 0.243 0.000
Z93.1 Gastrostomy status
0.757 0.243 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.757 0.243 0.000
Z94 Transplanted organ and tissue status
0.755 0.245 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.754 0.246 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.753 0.247 0.000
H20.9 Iridocyclitis, unspecified
0.750 0.250 0.000
H04.8 Other disorders of lachrymal system
0.750 0.250 0.000
Z48 Other surgical follow-up care
0.749 0.251 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.749 0.251 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.748 0.251 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.748 0.252 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.747 0.253 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.747 0.253 0.000
E00-E07 Disorders of thyroid gland
0.747 0.253 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.746 0.254 0.000
W20-W49 Exposure to inanimate mechanical forces
0.745 0.255 0.000
Q80-Q89 Other congenital malformations
0.745 0.255 0.000
C34 Malignant neoplasm of bronchus and lung
0.744 0.256 0.000
E89.2 Postprocedural hypoparathyroidism
0.741 0.259 0.000
E23 Hypofunction and other disorders of pituitary gland
0.740 0.260 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.740 0.260 0.000
Z85.6 Personal history of leukaemia
0.739 0.261 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.738 0.261 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.738 0.262 0.000
V10-V19 Pedal cyclist injured in transport accident
0.737 0.263 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.737 0.263 0.000
E87.7 Fluid overload
0.736 0.264 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.735 0.265 0.000
J64 Unspecified pneumoconiosis
0.735 0.265 0.000
O85-O92 Complications predominantly related to the puerperium
0.734 0.265 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.734 0.266 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.734 0.266 0.000
C44 Other malignant neoplasms of skin
0.732 0.268 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.730 0.269 0.000
Z98 Other postsurgical states
0.730 0.270 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.729 0.271 0.000
H15 Disorders of sclera
0.729 0.271 0.000
Y60.4 During endoscopic examination
0.728 0.272 0.000
E16 Other disorders of pancreatic internal secretion
0.728 0.272 0.000
Z93.9 Artificial opening status, unspecified
0.728 0.272 0.000
S42 Fracture of shoulder and upper arm
0.727 0.273 0.000
J90-J94 Other diseases of pleura
0.727 0.273 0.000
E22 Hyperfunction of pituitary gland
0.726 0.274 0.000
Z52 Donors of organs and tissues
0.724 0.276 0.000
E87.3 Alkalosis
0.723 0.277 0.000
Z81 Family history of mental and behavioural disorders
0.723 0.277 0.000
T82.3 Mechanical complication of other vascular grafts
0.721 0.279 0.000
C44.4 Skin of scalp and neck
0.719 0.281 0.000
H36.0 Diabetic retinopathy
0.719 0.281 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.718 0.282 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.718 0.282 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.718 0.282 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.718 0.282 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.718 0.282 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.718 0.282 0.000
T17 Foreign body in respiratory tract
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.717 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.717 0.283 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.716 0.284 0.000
Y83.3 Surgical operation with formation of external stoma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
H74.0 Tympanosclerosis
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.289 0.000
Y65 Other misadventures during surgical and medical care
0.710 0.290 0.000
E85 Amyloidosis
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.709 0.291 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.708 0.292 0.000
E83.8 Other disorders of mineral metabolism
0.708 0.292 0.000
E83.2 Disorders of zinc metabolism
0.708 0.292 0.000
E83.0 Disorders of copper metabolism
0.708 0.292 0.000
X60-X84 Intentional self-harm
0.707 0.293 0.000
Y43.3 Other antineoplastic drugs
0.707 0.293 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.707 0.293 0.000
T66-T78 Other and unspecified effects of external causes
0.706 0.293 0.000
E29 Testicular dysfunction
0.706 0.294 0.000
Z44 Fitting and adjustment of external prosthetic device
0.705 0.295 0.000
S72 Fracture of femur
0.704 0.295 0.000
B07 Viral warts
0.704 0.296 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.704 0.296 0.000
Z46 Fitting and adjustment of other devices
0.703 0.297 0.000
E24 Cushing's syndrome
0.703 0.297 0.000
Z90.2 Acquired absence of lung [part of]
0.702 0.298 0.000
Chapter VI Diseases of the nervous system
0.702 0.298 0.000
H21 Other disorders of iris and ciliary body
0.701 0.299 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.700 0.300 0.000
Z80.6 Family history of leukaemia
0.700 0.300 0.000
H65.3 Chronic mucoid otitis media
0.700 0.300 0.000
Z92.0 Personal history of contraception
0.699 0.301 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.699 0.301 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.698 0.302 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.303 0.000
E73 Lactose intolerance
0.697 0.303 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.696 0.303 0.000
V48 Car occupant injured in noncollision transport accident
0.696 0.304 0.000
Z84 Family history of other conditions
0.696 0.304 0.000
S32 Fracture of lumbar spine and pelvis
0.695 0.305 0.000
E26 Hyperaldosteronism
0.694 0.305 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.693 0.307 0.000
C73 Malignant neoplasm of thyroid gland
0.690 0.310 0.000
Z49 Care involving dialysis
0.690 0.310 0.000
C34.3 Lower lobe, bronchus or lung
0.689 0.311 0.000
E27.2 Addisonian crisis
0.688 0.311 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.688 0.312 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.688 0.312 0.000
E87.4 Mixed disorder of acid-base balance
0.687 0.313 0.000
H11 Other disorders of conjunctiva
0.687 0.313 0.000
S90-S99 Injuries to the ankle and foot
0.686 0.314 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.686 0.314 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.685 0.315 0.000
H70 Mastoiditis and related conditions
0.685 0.315 0.000
H68 Eustachian salpingitis and obstruction
0.685 0.315 0.000
H67 Otitis media in diseases classified elsewhere
0.685 0.315 0.000
H53-H54 Visual disturbances and blindness
0.685 0.315 0.000
H01.9 Inflammation of eyelid, unspecified
0.684 0.316 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.684 0.316 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.683 0.317 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.683 0.317 0.000
T83.2 Mechanical complication of graft of urinary organ
0.683 0.317 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.683 0.317 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.683 0.317 0.000
D00-D09 In situ neoplasms
0.682 0.318 0.000
J18.0 Bronchopneumonia, unspecified
0.680 0.320 0.000
J11 Influenza, virus not identified
0.679 0.321 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.676 0.324 0.000
H16.8 Other keratitis
0.676 0.324 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.675 0.325 0.000
E32 Diseases of thymus
0.675 0.325 0.000
E31 Polyglandular dysfunction
0.675 0.325 0.000
E30 Disorders of puberty, not elsewhere classified
0.675 0.325 0.000
E25 Adrenogenital disorders
0.675 0.325 0.000
S41.1 Open wound of upper arm
0.674 0.325 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.674 0.326 0.000
Z83.6 Family history of diseases of the respiratory system
0.673 0.326 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.673 0.326 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.673 0.326 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.673 0.326 0.000
S70 Superficial injury of hip and thigh
0.673 0.327 0.000
T14 Injury of unspecified body region
0.671 0.329 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.670 0.330 0.000
E20 Hypoparathyroidism
0.670 0.330 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.669 0.330 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.669 0.330 0.000
H17 Corneal scars and opacities
0.669 0.330 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.669 0.331 0.000
H74.4 Polyp of middle ear
0.669 0.331 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.668 0.332 0.000
Y64 Contaminated medical or biological substances
0.668 0.332 0.000
Y63 Failure in dosage during surgical and medical care
0.668 0.332 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.668 0.332 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.668 0.332 0.000
Y69 Unspecified misadventure during surgical and medical care
0.668 0.332 0.000
Y66 Nonadministration of surgical and medical care
0.668 0.332 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.668 0.332 0.000
H20.8 Other iridocyclitis
0.668 0.332 0.000
E89.3 Postprocedural hypopituitarism
0.668 0.332 0.000
H66.3 Other chronic suppurative otitis media
0.667 0.333 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.666 0.334 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.665 0.335 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.665 0.335 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.665 0.335 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.665 0.335 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.665 0.335 0.000
C34.0 Main bronchus
0.665 0.335 0.000
Z93.8 Other artificial opening status
0.664 0.336 0.000
Z48.9 Surgical follow-up care, unspecified
0.664 0.336 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.664 0.336 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.663 0.337 0.000
B02 Zoster [herpes zoster]
0.662 0.338 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.662 0.338 0.000
W06 Fall involving bed
0.661 0.339 0.000
T87 Complications peculiar to reattachment and amputation
0.661 0.339 0.000
C44.2 Skin of ear and external auricular canal
0.661 0.339 0.000
S61 Open wound of wrist and hand
0.660 0.340 0.000
Z63 Other problems related to primary support group, including family circumstances
0.660 0.340 0.000
Z58 Problems related to physical environment
0.659 0.340 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.659 0.341 0.000
H80-H83 Diseases of inner ear
0.659 0.341 0.000
H20.1 Chronic iridocyclitis
0.659 0.341 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.659 0.341 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.658 0.342 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.658 0.342 0.000
E45 Retarded development following protein-energy malnutrition
0.658 0.342 0.000
E43 Unspecified severe protein-energy malnutrition
0.658 0.342 0.000
E42 Marasmic kwashiorkor
0.658 0.342 0.000
E41 Nutritional marasmus
0.658 0.342 0.000
E40 Kwashiorkor
0.658 0.342 0.000
S48 Traumatic amputation of shoulder and upper arm
0.657 0.343 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.657 0.343 0.000
S44 Injury of nerves at shoulder and upper arm level
0.657 0.343 0.000
S47 Crushing injury of shoulder and upper arm
0.657 0.343 0.000
T17.2 Foreign body in pharynx
0.655 0.345 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.654 0.346 0.000
G20-G26 Extrapyramidal and movement disorders
0.653 0.347 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.653 0.347 0.000
E87.2 Acidosis
0.652 0.348 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.652 0.348 0.000
E34 Other endocrine disorders
0.651 0.349 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.651 0.349 0.000
C64-C68 Malignant neoplasms of urinary tract
0.649 0.351 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.648 0.352 0.000
E16.2 Hypoglycaemia, unspecified
0.647 0.353 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.646 0.354 0.000
Z83.5 Family history of eye and ear disorders
0.646 0.354 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.646 0.354 0.000
H73.1 Chronic myringitis
0.646 0.354 0.000
H73.0 Acute myringitis
0.646 0.354 0.000
S62 Fracture at wrist and hand level
0.646 0.354 0.000
U88 Agent resistant to multiple antibiotics
0.646 0.354 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.645 0.355 0.000
J17 Pneumonia in diseases classified elsewhere
0.645 0.355 0.000
H69 Other disorders of Eustachian tube
0.645 0.355 0.000
Z29 Need for other prophylactic measures
0.645 0.355 0.000
S12 Fracture of neck
0.644 0.356 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.644 0.356 0.000
J90 Pleural effusion, not elsewhere classified
0.643 0.357 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.642 0.358 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.642 0.358 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.642 0.358 0.000
E89.5 Postprocedural testicular hypofunction
0.642 0.358 0.000
E89.4 Postprocedural ovarian failure
0.642 0.358 0.000
E89.1 Postprocedural hypoinsulinaemia
0.642 0.358 0.000
E28 Ovarian dysfunction
0.642 0.358 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.642 0.358 0.000
W19 Unspecified fall
0.641 0.358 0.000
Z40.9 Prophylactic surgery, unspecified
0.641 0.359 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.641 0.359 0.000
G25 Other extrapyramidal and movement disorders
0.641 0.359 0.000
H31 Other disorders of choroid
0.640 0.359 0.000
E53 Deficiency of other B group vitamins
0.640 0.360 0.000
Z57.3 Occupational exposure to other air contaminants
0.638 0.362 0.000
Z56 Problems related to employment and unemployment
0.637 0.363 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.637 0.363 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.637 0.363 0.000
J69 Pneumonitis due to solids and liquids
0.635 0.365 0.000
E55 Vitamin D deficiency
0.634 0.366 0.000
V20-V29 Motorcycle rider injured in transport accident
0.633 0.366 0.000
E61 Deficiency of other nutrient elements
0.634 0.366 0.000
Y60.9 During unspecified surgical and medical care
0.633 0.367 0.000
Y60.8 During other surgical and medical care
0.633 0.367 0.000
Y60.7 During administration of enema
0.633 0.367 0.000
Y60.6 During aspiration, puncture and other catheterisation
0.633 0.367 0.000
Y60.5 During heart catheterisation
0.633 0.367 0.000
Y60.3 During injection or immunisation
0.633 0.367 0.000
Y60.2 During kidney dialysis or other perfusion
0.633 0.367 0.000
Y60.1 During infusion or transfusion
0.633 0.367 0.000
H16.0 Corneal ulcer
0.633 0.367 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.633 0.367 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.632 0.368 0.000
H74.1 Adhesive middle ear disease
0.632 0.368 0.000
H04.9 Disorder of lachrymal system, unspecified
0.632 0.368 0.000
H04.6 Other changes in lachrymal passages
0.632 0.368 0.000
H04.4 Chronic inflammation of lachrymal passages
0.632 0.368 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.632 0.368 0.000
H04.0 Dacryoadenitis
0.632 0.368 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.632 0.368 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.632 0.368 0.000
E27.9 Disorder of adrenal gland, unspecified
0.631 0.369 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.631 0.369 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.630 0.370 0.000
Y42.5 Other oestrogens and progestogens
0.629 0.370 0.000
E27.5 Adrenomedullary hyperfunction
0.629 0.371 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.629 0.371 0.000
E27.0 Other adrenocortical overactivity
0.629 0.371 0.000
H72 Perforation of tympanic membrane
0.629 0.371 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.629 0.371 0.000
V80-V89 Other land transport accidents
0.629 0.371 0.000
Z65 Problems related to other psychosocial circumstances
0.629 0.371 0.000
Z64 Problems related to certain psychosocial circumstances
0.629 0.371 0.000
Z62 Other problems related to upbringing
0.629 0.371 0.000
Z61 Problems related to negative life events in childhood
0.629 0.371 0.000
Z59 Problems related to housing and economic circumstances
0.629 0.371 0.000
Z55 Problems related to education and literacy
0.629 0.371 0.000
S65 Injury of blood vessels at wrist and hand level
0.629 0.371 0.000
Z93.0 Tracheostomy status
0.628 0.371 0.000
S40.0 Contusion of shoulder and upper arm
0.628 0.372 0.000
S72.3 Fracture of shaft of femur
0.626 0.374 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.625 0.375 0.000
T11 Other injuries of upper limb, level unspecified
0.625 0.375 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.624 0.376 0.000
Q89 Other congenital malformations, not elsewhere classified
0.623 0.377 0.000
Y40 Systemic antibiotics
0.623 0.377 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.623 0.377 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.623 0.377 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.622 0.378 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.621 0.379 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.620 0.380 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.620 0.380 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.620 0.380 0.000
Z48.0 Attention to surgical dressings and sutures
0.619 0.381 0.000
J70 Respiratory conditions due to other external agents
0.619 0.381 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.619 0.381 0.000
J66 Airway disease due to specific organic dust
0.619 0.381 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.619 0.381 0.000
J62 Pneumoconiosis due to dust containing silica
0.619 0.381 0.000
J65 Pneumoconiosis associated with tuberculosis
0.619 0.381 0.000
J60 Coalworker's pneumoconiosis
0.619 0.381 0.000
Q50-Q56 Congenital malformations of genital organs
0.618 0.382 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.618 0.382 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.618 0.382 0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
0.616 0.384 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.614 0.386 0.000
B50-B64 Protozoal diseases
0.613 0.386 0.000
H52 Disorders of refraction and accommodation
0.613 0.387 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.612 0.388 0.000
W18 Other fall on same level
0.612 0.388 0.000
T86.0 Bone-marrow transplant rejection
0.611 0.389 0.000
W11 Fall on and from ladder
0.611 0.389 0.000
Y59 Other and unspecified vaccines and biological substances
0.610 0.389 0.000
Y58 Bacterial vaccines
0.610 0.389 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.610 0.389 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.610 0.389 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.610 0.389 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.610 0.389 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.610 0.389 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.610 0.389 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.610 0.390 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.610 0.390 0.000
J12 Viral pneumonia, not elsewhere classified
0.610 0.390 0.000
J09 Influenza due to certain identified influenza virus
0.610 0.390 0.000
W19.4 Street and highway
0.609 0.391 0.000
H20.2 Lens-induced iridocyclitis
0.609 0.391 0.000
Q00-Q07 Congenital malformations of the nervous system
0.608 0.392 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.608 0.392 0.000
S68 Traumatic amputation of wrist and hand
0.607 0.393 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.607 0.393 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.606 0.393 0.000
Z98.1 Arthrodesis status
0.606 0.394 0.000
S41.0 Open wound of shoulder
0.606 0.394 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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