TreeWAS – Variant ID: rs2681472

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.990	0.010	0.000
I25 Chronic ischaemic heart disease	0.987	0.013	0.000
I25.1 Atherosclerotic heart disease	0.971	0.029	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.957	0.043	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.844	0.156	0.000
I10-I15 Hypertensive diseases	0.000	0.169	0.831
I25.3 Aneurysm of heart	0.810	0.190	0.000
I12 Hypertensive renal disease	0.000	0.204	0.796
I25.5 Ischaemic cardiomyopathy	0.765	0.235	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.280	0.720
I12.9 Hypertensive renal disease without renal failure	0.000	0.280	0.720
I25.6 Silent myocardial ischaemia	0.707	0.292	0.000
I25.4 Coronary artery aneurysm	0.706	0.294	0.000
I15 Secondary hypertension	0.000	0.351	0.649
I13 Hypertensive heart and renal disease	0.000	0.404	0.596
I15.1 Hypertension secondary to other renal disorders	0.000	0.414	0.586
I25.0 Atherosclerotic cardiovascular disease, so described	0.542	0.458	0.000
I11 Hypertensive heart disease	0.000	0.466	0.534
I15.2 Hypertension secondary to endocrine disorders	0.000	0.535	0.465
I15.0 Renovascular hypertension	0.000	0.535	0.465
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.572	0.427
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.572	0.427
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.572	0.427
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.572	0.427
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.575	0.425
I15.9 Seconday hypertension, unspecified	0.000	0.594	0.406
I15.8 Other secondary hypertension	0.001	0.643	0.357
I11.0 Hypertensive heart disease with (congestive) heart failure	0.001	0.759	0.240
G81.9 Hemiplegia, unspecified	0.000	0.872	0.128
G81 Hemiplegia	0.000	0.942	0.058
I20-I25 Ischaemic heart diseases	0.056	0.943	0.001
G81.0 Flaccid hemiplegia	0.000	0.958	0.042
I22 Subsequent myocardial infarction	0.041	0.959	0.000
G81.1 Spastic hemiplegia	0.000	0.961	0.039
I23 Certain current complications following acute myocardial infarction	0.037	0.963	0.001
I22.0 Subsequent myocardial infarction of anterior wall	0.032	0.968	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.031	0.969	0.000
I22.8 Subsequent myocardial infarction of other sites	0.029	0.970	0.000
I24 Other acute ischaemic heart diseases	0.028	0.972	0.000
I27 Other pulmonary heart diseases	0.000	0.973	0.027
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.026	0.973	0.001
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.026	0.973	0.001
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.026	0.973	0.001
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.026	0.973	0.001
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.026	0.973	0.001
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.026	0.973	0.001
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.026	0.973	0.001
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.975	0.025
I27.0 Primary pulmonary hypertension	0.000	0.975	0.025
Chapter IX Diseases of the circulatory system	0.000	0.975	0.025
I27.9 Pulmonary heart disease, unspecified	0.000	0.975	0.025
I22.1 Subsequent myocardial infarction of inferior wall	0.024	0.975	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.024	0.976	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.977	0.023
I23.8 Other current complications following acute myocardial infarction	0.022	0.977	0.001
I21 Acute myocardial infarction	0.022	0.978	0.000
I24.1 Dressler's syndrome	0.022	0.978	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.979	0.021
I61 Intracerebral haemorrhage	0.000	0.979	0.021
I28 Other diseases of pulmonary vessels	0.000	0.979	0.021
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.979	0.021
I60-I69 Cerebrovascular diseases	0.000	0.979	0.021
I69 Sequelae of cerebrovascular disease	0.000	0.980	0.020
I27.1 Kyphoscoliotic heart disease	0.000	0.980	0.020
I05-I09 Chronic rheumatic heart diseases	0.000	0.980	0.020
I21.3 Acute transmural myocardial infarction of unspecified site	0.019	0.980	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.981	0.019
I21.2 Acute transmural myocardial infarction of other sites	0.019	0.981	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.982	0.018
I00-I02 Acute rheumatic fever	0.000	0.982	0.018
I28.8 Other specified diseases of pulmonary vessels	0.000	0.982	0.018
I08 Multiple valve diseases	0.000	0.982	0.018
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.983	0.017
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.983	0.017
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.983	0.017
I69.3 Sequelae of cerebral infarction	0.000	0.983	0.017
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.983	0.016
I21.X Presumed acute myicardial infaction (unconfirmed)	0.016	0.984	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.984	0.016
I62 Other nontraumatic intracranial haemorrhage	0.000	0.984	0.016
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.984	0.016
I60 Subarachnoid haemorrhage	0.000	0.984	0.016
I21.0 Acute transmural myocardial infarction of anterior wall	0.016	0.984	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.984	0.016
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.985	0.015
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.985	0.015
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.985	0.015
I28.1 Aneurysm of pulmonary artery	0.000	0.985	0.015
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.985	0.015
I61.8 Other intracerebral haemorrhage	0.000	0.985	0.015
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.985	0.015
I20 Angina pectoris	0.015	0.985	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.985	0.015
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.985	0.014
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.985	0.015
I09 Other rheumatic heart diseases	0.000	0.986	0.014
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.986	0.014
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.986	0.014
I02 Rheumatic chorea	0.000	0.987	0.013
I01 Rheumatic fever with heart involvement	0.000	0.987	0.013
I00 Rheumatic fever without mention of heart involvement	0.000	0.987	0.013
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.987	0.013
I06 Rheumatic aortic valve diseases	0.000	0.987	0.013
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.987	0.013
I08.9 Multiple valve disease, unspecified	0.000	0.987	0.013
Z29 Need for other prophylactic measures	0.000	0.987	0.013
Z29.1 Prophylactic immunotherapy	0.000	0.987	0.013
I08.8 Other multiple valve diseases	0.000	0.987	0.012
I07.1 Tricuspid insufficiency	0.000	0.987	0.012
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.988	0.012
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.988	0.012
Z29.8 Other specified prophylactic measures	0.000	0.988	0.012
I20.9 Angina pectoris, unspecified	0.012	0.988	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.988	0.012
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.988	0.012
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.988	0.012
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.988	0.012
I62.1 Nontraumatic extradural haemorrhage	0.000	0.988	0.012
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.988	0.011
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.988	0.011
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.988	0.012
I07.9 Tricuspid valve disease, unspecified	0.000	0.989	0.011
I07.8 Other tricuspid valve diseases	0.000	0.989	0.011
I07.2 Tricuspid stenosis with insufficiency	0.000	0.989	0.011
I07.0 Tricuspid stenosis	0.000	0.989	0.011
Z29.0 Isolation	0.000	0.989	0.011
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.989	0.011
I05 Rheumatic mitral valve diseases	0.000	0.989	0.011
I60.8 Other subarachnoid haemorrhage	0.000	0.989	0.011
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.989	0.011
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.989	0.011
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.989	0.011
I68.0 Cerebral amyloid angiopathy	0.000	0.989	0.011
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.989	0.011
I21.4 Acute subendocardial myocardial infarction	0.011	0.989	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.989	0.011
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.989	0.011
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.989	0.011
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.989	0.011
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.989	0.011
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.989	0.011
I09.8 Other specified rheumatic heart diseases	0.000	0.989	0.010
I09.2 Chronic rheumatic pericarditis	0.000	0.989	0.010
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.989	0.010
I09.0 Rheumatic myocarditis	0.000	0.989	0.010
G82 Paraplegia and tetraplegia	0.000	0.989	0.011
I09.9 Rheumatic heart disease, unspecified	0.000	0.990	0.010
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.990	0.010
I24.8 Other forms of acute ischaemic heart disease	0.010	0.990	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.990	0.010
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.990	0.010
I01.8 Other acute rheumatic heart disease	0.000	0.990	0.010
I01.2 Acute rheumatic myocarditis	0.000	0.990	0.010
I01.1 Acute rheumatic endocarditis	0.000	0.990	0.010
I01.0 Acute rheumatic pericarditis	0.000	0.990	0.010
I02.9 Rheumatic chorea without heart involvement	0.000	0.990	0.010
I02.0 Rheumatic chorea with heart involvement	0.000	0.990	0.010
S22.10 Multiple fractures of thoracic spine (closed)	0.010	0.990	0.000
S27 Injury of other and unspecified intrathoracic organs	0.010	0.990	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.990	0.010
S20-S29 Injuries to the thorax	0.010	0.990	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.990	0.009
I06.8 Other rheumatic aortic valve diseases	0.000	0.990	0.009
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.990	0.009
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.991	0.009
S22.1 Multiple fractures of thoracic spine	0.009	0.991	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.991	0.009
S22 Fracture of rib(s), sternum and thoracic spine	0.009	0.991	0.000
S27.0 Traumatic pneumothorax	0.009	0.991	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.991	0.009
G82.1 Spastic paraplegia	0.000	0.991	0.009
I06.0 Rheumatic aortic stenosis	0.000	0.991	0.009
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.009	0.991	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.009	0.991	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.991	0.009
I20.1 Angina pectoris with documented spasm	0.008	0.991	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.991	0.008
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.991	0.008
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.991	0.008
I65.1 Occlusion and stenosis of basilar artery	0.000	0.991	0.008
S29 Other and unspecified injuries of thorax	0.008	0.992	0.000
I06.1 Rheumatic aortic insufficiency	0.000	0.992	0.008
S20 Superficial injury of thorax	0.008	0.992	0.000
I05.0 Mitral stenosis	0.000	0.992	0.008
S27.1 Traumatic haemothorax	0.008	0.992	0.000
I05.8 Other mitral valve diseases	0.000	0.992	0.008
G82.4 Spastic tetraplegia	0.000	0.992	0.008
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.992	0.008
I26 Pulmonary embolism	0.000	0.992	0.008
S22.2 Fracture of sternum	0.008	0.992	0.000
S27.8 Injury of other specified intrathoracic organs	0.008	0.992	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.008	0.992	0.000
G82.3 Flaccid tetraplegia	0.000	0.992	0.008
G82.0 Flaccid paraplegia	0.000	0.992	0.008
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.992	0.008
S21 Open wound of thorax	0.008	0.992	0.000
G82.2 Paraplegia, unspecified	0.000	0.992	0.008
S27.3 Other injuries of lung	0.007	0.992	0.000
G83 Other paralytic syndromes	0.000	0.992	0.007
S29.9 Unspecified injury of thorax	0.008	0.992	0.000
G80 Infantile cerebral palsy	0.000	0.993	0.007
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.007	0.993	0.000
S24 Injury of nerves and spinal cord at thorax level	0.007	0.993	0.000
S20.2 Contusion of thorax	0.007	0.993	0.000
S27.9 Injury of unspecified intrathoracic organ	0.007	0.993	0.000
S27.7 Multiple injuries of intrathoracic organs	0.007	0.993	0.000
S27.6 Injury of pleura	0.007	0.993	0.000
S27.5 Injury of thoracic trachea	0.007	0.993	0.000
S27.4 Injury of bronchus	0.007	0.993	0.000
S20.1 Other and unspecified superficial injuries of breast	0.007	0.993	0.000
S20.4 Other superficial injuries of back wall of thorax	0.007	0.993	0.000
S22.4 Multiple fractures of ribs	0.007	0.993	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.007	0.993	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.007	0.993	0.000
S26 Injury of heart	0.007	0.993	0.000
S25 Injury of blood vessels of thorax	0.007	0.993	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.993	0.007
S22.5 Flail chest	0.007	0.993	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.993	0.007
S22.11 Multiple fractures of thoracic spine (open)	0.007	0.993	0.000
S22.20 Fracture of sternum (closed)	0.007	0.993	0.000
S22.9 Fracture of bony thorax, part unspecified	0.007	0.993	0.000
S22.8 Fracture of other parts of bony thorax	0.007	0.993	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.007	0.993	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.993	0.007
S22.3 Fracture of rib	0.007	0.993	0.000
S27.2 Traumatic heamopneumothorax	0.007	0.993	0.000
S21.2 Open wound of back wall of thorax	0.007	0.993	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.007	0.993	0.000
S29.8 Other specified injuries of thorax	0.006	0.994	0.000
S29.7 Multiple injuries of thorax	0.006	0.994	0.000
S29.0 Injury of muscle and tendon at thorax level	0.006	0.994	0.000
S20.7 Multiple superficial injuries of thorax	0.006	0.994	0.000
S20.0 Contusion of breast	0.006	0.994	0.000
I65.2 Occlusion and stenosis of carotid artery	0.000	0.994	0.006
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.006	0.994	0.000
G83.8 Other specified paralytic syndromes	0.000	0.994	0.006
T84.0 Mechanical complication of internal joint prosthesis	0.006	0.994	0.000
G83.9 Paralytic syndrome, unspecified	0.000	0.994	0.006
S22.21 Fracture of sternum (open)	0.006	0.994	0.000
G82.5 Tetraplegia, unspecified	0.000	0.994	0.006
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.006	0.994	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.006	0.994	0.000
S21.1 Open wound of front wall of thorax	0.006	0.994	0.000
S23.4 Sprain and strain of ribs and sternum	0.006	0.994	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.006	0.994	0.000
S21.8 Open wound of other parts of thorax	0.006	0.994	0.000
S21.7 Multiple open wounds of thoracic wall	0.006	0.994	0.000
S21.0 Open wound of breast	0.006	0.994	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.005	0.994	0.000
G83.5 Locked-in syndrome	0.000	0.994	0.006
G83.3 Monoplegia, unspecified	0.000	0.994	0.006
G83.0 Diplegia of upper limbs	0.000	0.994	0.006
G80.8 Other infantile cerebral palsy	0.000	0.994	0.005
G80.4 Ataxic cerebral palsy	0.000	0.994	0.005
G80.3 Dyskinetic cerebral palsy	0.000	0.994	0.005
G80.2 Infantile hemiplegia	0.000	0.994	0.005
M54.22 Cervicalgia (Cervical region)	0.006	0.994	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.005	0.994	0.000
S23.3 Sprain and strain of thoracic spine	0.005	0.994	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.005	0.994	0.000
S23.1 Dislocation of thoracic vertebra	0.005	0.994	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.005	0.994	0.000
S24.6 Injury of unspecified nerve of thorax	0.005	0.994	0.000
S24.5 Injury of other nerves of thorax	0.005	0.994	0.000
S24.4 Injury of thoracic sympathetic nerves	0.005	0.994	0.000
S24.3 Injury of peripheral nerves of thorax	0.005	0.994	0.000
S24.2 Injury of nerve root of thoracic spine	0.005	0.994	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.005	0.994	0.000
S22.40 Multiple fractures of ribs (closed)	0.006	0.994	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.005	0.994	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.005	0.994	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.005	0.994	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.005	0.994	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.005	0.994	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.005	0.994	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.005	0.994	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.005	0.994	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.005	0.994	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.005	0.994	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.994	0.005
S32.00 Fracture of lumbar vertebra (closed)	0.005	0.994	0.000
G80.0 Spastic cerebral palsy	0.000	0.994	0.005
S22.50 Flail chest (closed)	0.005	0.995	0.000
S20.3 Other superficial injuries of front wall of thorax	0.005	0.995	0.000
S22.41 Multiple fractures of ribs (open)	0.005	0.995	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.995	0.005
S25.9 Injury of unspecified blood vessel of thorax	0.005	0.995	0.000
S25.8 Injury of other blood vessels of thorax	0.005	0.995	0.000
S25.7 Injury of multiple blood vessels of thorax	0.005	0.995	0.000
S25.5 Injury of intercostal blood vessels	0.005	0.995	0.000
S25.4 Injury of pulmonary blood vessels	0.005	0.995	0.000
S25.3 Injury of innominate or subclavian vein	0.005	0.995	0.000
S25.2 Injury of superior vena cava	0.005	0.995	0.000
S25.1 Injury of innominate or subclavian artery	0.005	0.995	0.000
S25.0 Injury of thoracic aorta	0.005	0.995	0.000
S26.9 Injury of heart, unspecified	0.005	0.995	0.000
S26.8 Other injuries of heart	0.005	0.995	0.000
S26.0 Injury of heart with haemopericardium	0.005	0.995	0.000
S28.1 Traumatic amputation of part of thorax	0.005	0.995	0.000
S28.0 Crushed chest	0.005	0.995	0.000
S22.51 Flail chest (open)	0.005	0.995	0.000
M20.5 Other deformities of toe(s) (acquired)	0.005	0.995	0.000
G80.1 Spastic diplegia	0.000	0.995	0.005
I67 Other cerebrovascular diseases	0.000	0.995	0.005
I05.9 Mitral valve disease, unspecified	0.000	0.995	0.005
S21.9 Open wound of thorax, part unspecified	0.005	0.995	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.005	0.995	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.005	0.995	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.005	0.995	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.005	0.995	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.995	0.005
I20.0 Unstable angina	0.005	0.995	0.000
S22.31 Fracture of rib (open)	0.005	0.995	0.000
M06.9 Rheumatoid arthritis, unspecified	0.005	0.995	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.005	0.995	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.995	0.005
S22.0 Fracture of thoracic vertebra	0.005	0.995	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.005	0.995	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.005	0.995	0.000
G83.2 Monoplegia of upper limb	0.000	0.995	0.005
S22.30 Fracture of rib (closed)	0.005	0.995	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.995	0.005
R45.1 Restlessness and agitation	0.005	0.995	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.995	0.005
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.995	0.005
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.005	0.995	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.005	0.995	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.005	0.995	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
D23.5 Skin of trunk	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.995	0.005
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.005	0.995	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.005	0.995	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.005	0.995	0.000
M16.9 Coxarthrosis, unspecified	0.005	0.995	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.005	0.995	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.005	0.995	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.995	0.004
T84.3 Mechanical complication of other bone devices, implants and grafts	0.004	0.996	0.000
G83.1 Monoplegia of lower limb	0.000	0.996	0.004
I97.1 Other functional disturbances following cardiac surgery	0.000	0.996	0.004
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.996	0.004
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
M54.39 Sciatica (Site unspecified)	0.004	0.996	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.996	0.004
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.996	0.004
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.996	0.004
I97.0 Postcardiotomy syndrome	0.000	0.996	0.004
G83.4 Cauda equina syndrome	0.000	0.996	0.004
M06.98 Rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.996	0.004
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.004	0.996	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.004	0.996	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.004	0.996	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.004	0.996	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.004	0.996	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.004	0.996	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.996	0.004
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.996	0.004
I67.5 Moyamoya disease	0.000	0.996	0.004
I67.4 Hypertensive encephalopathy	0.000	0.996	0.004
I67.3 Progressive vascular leukoencephalopathy	0.000	0.996	0.004
N31.8 Other neuromuscular dysfunction of bladder	0.004	0.996	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
S22.01 Fracture of thoracic vertebra (open)	0.004	0.996	0.000
O14.0 Moderate preeclampsia	0.000	0.996	0.004
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
O15 Eclampsia	0.000	0.996	0.004
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.996	0.004
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.996	0.004
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
I98.0 Cardiovascular syphilis	0.000	0.996	0.004
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
M06 Other rheumatoid arthritis	0.004	0.996	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.004	0.996	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.004	0.996	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
K04.8 Radicular cyst	0.004	0.996	0.000
I67.2 Cerebral atherosclerosis	0.000	0.996	0.004
S32.0 Fracture of lumbar vertebra	0.004	0.996	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.996	0.003
R45.0 Nervousness	0.004	0.996	0.000
M06.3 Rheumatoid nodule	0.004	0.996	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.996	0.004
O12.0 Gestational oedema	0.000	0.996	0.004
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.003	0.996	0.000
M54.2 Cervicalgia	0.004	0.996	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.004	0.996	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.996	0.004
M05 Seropositive rheumatoid arthritis	0.004	0.996	0.000
O16 Unspecified maternal hypertension	0.000	0.996	0.004
I67.9 Cerebrovascular disease, unspecified	0.000	0.997	0.003
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.997	0.003
R45 Symptoms and signs involving emotional state	0.003	0.997	0.000
O12.1 Gestational proteinuria	0.000	0.997	0.003
O14.2 HELLP syndrome	0.000	0.997	0.003
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O14.9 Preeclampsia, unspecified	0.000	0.997	0.003
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.997	0.003
O12.2 Gestational oedema with proteinuria	0.000	0.997	0.003
O14.1 Severe preeclampsia	0.000	0.997	0.003
M54.29 Cervicalgia-Site unspe	0.003	0.997	0.000
I21.9 Acute myocardial infarction, unspecified	0.003	0.997	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.997	0.003
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
R32 Unspecified urinary incontinence	0.003	0.997	0.000
M06.0 Seronegative rheumatoid arthritis	0.003	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.003	0.997	0.000
K51.8 Other ulcerative colitis	0.003	0.997	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.997	0.003
O15.2 Eclampsia in the puerperium	0.000	0.997	0.003
O15.1 Eclampsia in labour	0.000	0.997	0.003
O15.0 Eclampsia in pregnancy	0.000	0.997	0.003
Z04.8 Examination and observation for other specified reasons	0.003	0.997	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.003	0.997	0.000
M05.1 Rheumatoid lung disease	0.003	0.997	0.000
R45.2 Unhappiness	0.003	0.997	0.000
M06.8 Other specified rheumatoid arthritis	0.003	0.997	0.000
M06.2 Rheumatoid bursitis	0.003	0.997	0.000
M06.1 Adult-onset Still's disease	0.003	0.997	0.000
S32.01 Fracture of lumbar vertebra (open)	0.003	0.997	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.003	0.997	0.000
M06.38 Rheumatoid nodule (Other)	0.003	0.997	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.003	0.997	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.003	0.997	0.000
M06.33 Rheumatoid nodule (Forearm)	0.003	0.997	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.003	0.997	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.003	0.997	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.003	0.997	0.000
I86.1 Scrotal varices	0.000	0.997	0.003
Q66 Congenital deformities of feet	0.003	0.997	0.000
M06.34 Rheumatoid nodule (Hand)	0.003	0.997	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.003	0.997	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.997	0.003
M54.28 Cervicalgia-Sacral/sacrococ	0.003	0.997	0.000
M54.27 Cervicalgia-Lumbosacral	0.003	0.997	0.000
M54.26 Cervicalgia-Lumbar	0.003	0.997	0.000
M54.25 Cervicalgia-Thoracolumbar	0.003	0.997	0.000
M54.24 Cervicalgia-Thoracic	0.003	0.997	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.003	0.997	0.000
M54.20 Cervicalgia-Mult site	0.003	0.997	0.000
R45.6 Physical violence	0.003	0.997	0.000
M05.8 Other seropositive rheumatoid arthritis	0.003	0.997	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.997	0.000
M05.2 Rheumatoid vasculitis	0.003	0.997	0.000
M05.0 Felty's syndrome	0.003	0.997	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.003	0.997	0.000
R45.7 State of emotional shock and stress, unspecified	0.003	0.997	0.000
R45.3 Demoralisation and apathy	0.003	0.997	0.000
I95 Hypotension	0.000	0.997	0.003
H61.0 Perichondritis of external ear	0.003	0.997	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.003	0.997	0.000
R45.5 Hostility	0.003	0.997	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.997	0.003
Q66.7 Pes cavus	0.003	0.997	0.000
I95.8 Other hypotension	0.000	0.997	0.003
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
J31.0 Chronic rhinitis	0.003	0.997	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.003	0.997	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.997	0.000
Q76.0 Spina bifida occulta	0.002	0.997	0.000
R45.4 Irritability and anger	0.002	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.002	0.997	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.997	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.997	0.000
Q66.0 Talipes equinovarus	0.002	0.997	0.000
B35.1 Tinea unguium	0.000	0.997	0.002
L29.9 Pruritus, unspecified	0.002	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
S06 Intracranial injury	0.000	0.998	0.002
M05.18 Rheumatoid lung disease (Other)	0.002	0.998	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.002	0.998	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations