TreeWAS – Variant ID: rs2800702

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44.5 Skin of trunk	1.000	0.000	0.000
C44.3 Skin of other and unspecified parts of face	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
C44.4 Skin of scalp and neck	0.998	0.002	0.000
C44.2 Skin of ear and external auricular canal	0.997	0.003	0.000
C44.6 Skin of upper limb, including shoulder	0.996	0.004	0.000
C44.1 Skin of eyelid, including canthus	0.995	0.005	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.824	0.176	0.000
C44.7 Skin of lower limb, including hip	0.750	0.250	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
C44.0 Skin of lip	0.661	0.339	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.616	0.384	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.192	0.808	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.862	0.138
T45.0 Antiallergic and antiemetic drugs	0.000	0.864	0.136
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.864	0.136
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.865	0.135
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.870	0.130
T43.2 Other and unspecified antidepressants	0.000	0.870	0.130
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.872	0.127
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.874	0.126
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.879	0.121
T45.5 Anticoagulants	0.000	0.881	0.119
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.884	0.116
T40.2 Other opioids	0.000	0.885	0.115
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.889	0.111
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.890	0.110
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.891	0.109
T43.6 Psychostimulants with abuse potential	0.000	0.892	0.108
T40.4 Other synthetic narcotics	0.000	0.896	0.103
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.898	0.102
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.900	0.100
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.901	0.099
T45.8 Other primarily systemic and haematological agents	0.000	0.901	0.099
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.901	0.099
T45.6 Fibrinolysis-affecting drugs	0.000	0.901	0.099
T45.4 Iron and its compounds	0.000	0.901	0.099
T45.3 Enzymes, not elsewhere classified	0.000	0.901	0.099
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.901	0.099
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.902	0.098
T43.9 Psychotropic drug, unspecified	0.000	0.903	0.097
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.903	0.097
T45.2 Vitamins, not elsewhere classified	0.000	0.905	0.095
T40.6 Other and unspecified narcotics	0.000	0.905	0.095
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.906	0.094
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.906	0.094
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.906	0.094
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.906	0.094
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.906	0.094
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.906	0.094
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.906	0.094
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.906	0.094
T44.0 Anticholinesterase agents	0.000	0.906	0.094
T50.8 Diagnostic agents	0.000	0.906	0.093
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.909	0.091
T50.4 Drugs affecting uric acid metabolism	0.000	0.909	0.091
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.909	0.091
T40.8 Lysergide [LSD]	0.000	0.909	0.091
T40.7 Cannabis (derivatives)	0.000	0.909	0.091
T40.3 Methadone	0.000	0.909	0.091
T40.1 Heroin	0.000	0.909	0.091
T40.0 Opium	0.000	0.909	0.091
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.911	0.089
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.911	0.089
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.911	0.089
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.911	0.089
T36 Poisoning by systemic antibiotics	0.000	0.914	0.086
T40.5 Cocaine	0.000	0.917	0.083
T50.7 Analeptics and opioid receptor antagonists	0.000	0.917	0.083
T50.5 Appetite depressants	0.000	0.917	0.083
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.917	0.083
T50.1 Loop [high-ceiling] diuretics	0.000	0.917	0.083
T50.0 Mineralocorticoids and their antagonists	0.000	0.917	0.083
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.918	0.082
T39.4 Antirheumatics, not elsewhere classified	0.000	0.922	0.078
T39.2 Pyrazolone derivatives	0.000	0.922	0.078
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.923	0.077
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.924	0.076
T39.1 4-Aminophenol derivatives	0.000	0.925	0.075
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.926	0.074
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.926	0.073
T41.5 Therapeutic gases	0.000	0.930	0.070
T41.4 Anaesthetic, unspecified	0.000	0.930	0.070
T41.3 Local anaesthetics	0.000	0.930	0.070
T41.2 Other and unspecified general anaesthetics	0.000	0.930	0.070
T41.1 Intravenous anaesthetics	0.000	0.930	0.070
T41.0 Inhaled anaesthetics	0.000	0.930	0.070
T39.0 Salicylates	0.000	0.931	0.069
T36.0 Penicillins	0.000	0.932	0.068
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.932	0.067
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.932	0.067
T47.7 Emetics	0.000	0.932	0.067
T47.6 Antidiarrhoeal drugs	0.000	0.932	0.067
T47.5 Digestants	0.000	0.932	0.067
T47.4 Other laxatives	0.000	0.932	0.067
T47.3 Saline and osmotic laxatives	0.000	0.932	0.067
T47.2 Stimulant laxatives	0.000	0.932	0.067
T47.0 Histamine H(2)-receptor antagonists	0.000	0.932	0.067
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.932	0.067
T37.5 Antiviral drugs	0.000	0.932	0.067
T37.4 Anthelminthics	0.000	0.932	0.067
T37.3 Other antiprotozoal drugs	0.000	0.932	0.067
T37.1 Antimycobacterial drugs	0.000	0.932	0.067
T37.0 Sulphonamides	0.000	0.932	0.067
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.934	0.066
T48.5 Anti-common-cold drugs	0.000	0.934	0.066
T48.4 Expectorants	0.000	0.934	0.066
T48.3 Antitussives	0.000	0.934	0.066
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.934	0.066
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.934	0.066
T48.0 Oxytocic drugs	0.000	0.934	0.066
T49.9 Topical agent, unspecified	0.000	0.936	0.064
T49.8 Other topical agents	0.000	0.936	0.064
T49.7 Dental drugs, topically applied	0.000	0.936	0.064
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.936	0.064
T49.5 Ophthalmological drugs and preparations	0.000	0.936	0.064
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.936	0.064
T49.3 Emollients, demulcents and protectants	0.000	0.936	0.064
T49.2 Local astringents and local detergents	0.000	0.936	0.064
T49.1 Antipruritics	0.000	0.936	0.064
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.936	0.064
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.936	0.064
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.936	0.064
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.937	0.063
T42.0 Hydantoin derivatives	0.000	0.937	0.062
T36.9 Systemic antibiotic, unspecified	0.000	0.938	0.062
T36.8 Other systemic antibiotics	0.000	0.938	0.062
T36.7 Antifungal antibiotics, systemically used	0.000	0.938	0.062
T36.6 Rifamycins	0.000	0.938	0.062
T36.5 Aminoglycosides	0.000	0.938	0.062
T36.4 Tetracyclines	0.000	0.938	0.062
T36.2 Chloramphenicol group	0.000	0.938	0.062
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.941	0.059
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.944	0.056
T42.1 Iminostilbenes	0.000	0.944	0.056
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.945	0.055
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.945	0.055
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.945	0.055
T42.2 Succinimides and oxazolidinediones	0.000	0.945	0.055
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.946	0.053
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.947	0.053
T36.3 Macrolides	0.000	0.948	0.051
T42.3 Barbiturates	0.000	0.951	0.048
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.951	0.049
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.952	0.048
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.954	0.046
T38.9 Other and unspecified hormone antagonists	0.000	0.954	0.046
T38.7 Androgens and anabolic congeners	0.000	0.954	0.046
T38.5 Other oestrogens and progestogens	0.000	0.954	0.046
T38.4 Oral contraceptives	0.000	0.954	0.046
T38.2 Antithyroid drugs	0.000	0.954	0.046
T38.0 Glucocorticoids and synthetic analogues	0.000	0.954	0.046
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.955	0.045
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.955	0.045
T46.7 Peripheral vasodilators	0.000	0.955	0.045
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.955	0.045
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.955	0.045
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.955	0.044
T38.1 Thyroid hormones and substitutes	0.000	0.956	0.044
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.958	0.042
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.958	0.042
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.958	0.041
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.962	0.038
T46.1 Calcium-channel blockers	0.000	0.965	0.035
K22.2 Oesophageal obstruction	0.030	0.970	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.970	0.029
C43 Malignant melanoma of skin	0.028	0.972	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.023	0.977	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.022	0.978	0.000
C43.4 Malignant melanoma of scalp and neck	0.021	0.979	0.000
T42.4 Benzodiazepines	0.000	0.979	0.021
C43.8 Overlapping malignant melanoma of skin	0.020	0.980	0.000
C43.0 Malignant melanoma of lip	0.020	0.980	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.017	0.983	0.000
Q80-Q89 Other congenital malformations	0.016	0.984	0.000
C43.9 Malignant melanoma of skin, unspecified	0.015	0.985	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.014	0.986	0.000
Q82 Other congenital malformations of skin	0.014	0.986	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.014	0.986	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.013	0.987	0.000
Q83 Congenital malformations of breast	0.013	0.987	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.013	0.987	0.000
Q87.4 Marfan's syndrome	0.013	0.987	0.000
Q85 Phakomatoses, not elsewhere classified	0.013	0.987	0.000
Q82.8 Other specified congenital malformations of skin	0.013	0.987	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.013	0.987	0.000
Q89 Other congenital malformations, not elsewhere classified	0.013	0.987	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.012	0.988	0.000
Q66 Congenital deformities of feet	0.012	0.988	0.000
Q66.8 Other congenital deformities of feet	0.012	0.988	0.000
Q44.6 Cystic disease of liver	0.012	0.988	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.012	0.988	0.000
Q82.5 Congenital nonneoplastic naevus	0.012	0.988	0.000
Q12.0 Congenital cataract	0.012	0.988	0.000
Q12 Congenital lens malformations	0.012	0.988	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.011	0.988	0.000
Q84 Other congenital malformations of integument	0.011	0.988	0.000
Q81 Epidermolysis bullosa	0.011	0.988	0.000
Q80 Congenital ichthyosis	0.011	0.988	0.000
Q45 Other congenital malformations of digestive system	0.011	0.989	0.000
Q83.8 Other congenital malformations of breast	0.011	0.989	0.000
Q85.9 Phakomatosis, unspecified	0.011	0.989	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.011	0.989	0.000
Q40 Other congenital malformations of upper alimentary tract	0.011	0.989	0.000
Q00-Q07 Congenital malformations of the nervous system	0.011	0.989	0.000
Q83.1 Accessory breast	0.011	0.989	0.000
Q89.2 Congenital malformations of other endocrine glands	0.011	0.989	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.011	0.989	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.010	0.989	0.000
Q66.9 Congenital deformity of feet, unspecified	0.010	0.989	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.010	0.990	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.010	0.990	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.010	0.990	0.000
Q44.7 Other congenital malformations of liver	0.010	0.990	0.000
Z50.8 Care involving use of rehabilitation procedures	0.010	0.990	0.000
Q82.9 Congenital malformation of skin, unspecified	0.010	0.990	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.010	0.990	0.000
Q82.3 Incontinentia pigmenti	0.010	0.990	0.000
Q82.1 Xeroderma pigmentosum	0.010	0.990	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.010	0.990	0.000
Q65 Congenital deformities of hip	0.010	0.990	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.010	0.990	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.010	0.990	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.010	0.990	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.010	0.990	0.000
Q82.2 Mastocytosis	0.010	0.990	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.010	0.990	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.010	0.990	0.000
Q83.9 Congenital malformation of breast, unspecified	0.010	0.990	0.000
Q83.2 Absent nipple	0.010	0.990	0.000
Q83.0 Congenital absence of breast with absent nipple	0.010	0.990	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.010	0.990	0.000
Q35-Q37 Cleft lip and cleft palate	0.010	0.990	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.010	0.990	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.010	0.990	0.000
Q83.3 Accessory nipple	0.009	0.990	0.000
Q85.1 Tuberous sclerosis	0.009	0.990	0.000
Q39 Congenital malformations of oesophagus	0.010	0.990	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.009	0.990	0.000
Q15 Other congenital malformations of eye	0.009	0.990	0.000
Q82.0 Hereditary lymphoedema	0.009	0.991	0.000
Q44.5 Other congenital malformations of bile ducts	0.009	0.991	0.000
Q44.4 Choledochal cyst	0.009	0.991	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.009	0.991	0.000
Q44.2 Atresia of bile ducts	0.009	0.991	0.000
Q44.1 Other congenital malformations of gallbladder	0.009	0.991	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.009	0.991	0.000
Q89.9 Congenital malformation, unspecified	0.009	0.991	0.000
Q89.8 Other specified congenital malformations	0.009	0.991	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.009	0.991	0.000
Q89.4 Conjoined twins	0.009	0.991	0.000
Q89.3 Situs inversus	0.009	0.991	0.000
Q89.1 Congenital malformations of adrenal gland	0.009	0.991	0.000
Q89.0 Congenital malformations of spleen	0.009	0.991	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.009	0.991	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.009	0.991	0.000
Q75 Other congenital malformations of skull and face bones	0.009	0.991	0.000
Q73 Reduction defects of unspecified limb	0.009	0.991	0.000
Q72 Reduction defects of lower limb	0.009	0.991	0.000
Q71 Reduction defects of upper limb	0.009	0.991	0.000
Q70 Syndactyly	0.009	0.991	0.000
Q69 Polydactyly	0.009	0.991	0.000
S01.5 Open wound of lip and oral cavity	0.009	0.991	0.000
Q03 Congenital hydrocephalus	0.009	0.991	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.991	0.009
Q66.6 Other congenital valgus deformities of feet	0.009	0.991	0.000
Q66.5 Congenital pes planus	0.009	0.991	0.000
Q66.4 Talipes calcaneovalgus	0.009	0.991	0.000
Q66.1 Talipes calcaneovarus	0.009	0.991	0.000
Q04 Other congenital malformations of brain	0.009	0.991	0.000
G25.3 Myoclonus	0.000	0.991	0.009
Q43 Other congenital malformations of intestine	0.009	0.991	0.000
Q40.2 Other specified congenital malformations of stomach	0.009	0.991	0.000
Q66.7 Pes cavus	0.009	0.991	0.000
Q66.2 Metatarsus varus	0.009	0.991	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.009	0.991	0.000
Q13 Congenital malformations of anterior segment of eye	0.009	0.991	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.009	0.991	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.009	0.991	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.009	0.991	0.000
Q07 Other congenital malformations of nervous system	0.009	0.991	0.000
Q66.3 Other congenital varus deformities of feet	0.009	0.991	0.000
Q45.8 Other specified congenital malformations of digestive system	0.009	0.991	0.000
Q68 Other congenital musculoskeletal deformities	0.009	0.991	0.000
Q14 Congenital malformations of posterior segment of eye	0.009	0.991	0.000
Q12.9 Congenital lens malformation, unspecified	0.008	0.991	0.000
Q12.8 Other congenital lens malformations	0.008	0.991	0.000
Q12.4 Spherophakia	0.008	0.991	0.000
Q12.3 Congenital aphakia	0.008	0.991	0.000
Q12.2 Coloboma of lens	0.008	0.991	0.000
Q12.1 Congenital displaced lens	0.008	0.991	0.000
Q66.0 Talipes equinovarus	0.008	0.991	0.000
Q17 Other congenital malformations of ear	0.008	0.991	0.000
Q40.1 Congenital hiatus hernia	0.008	0.991	0.000
Q80.9 Congenital ichthyosis, unspecified	0.008	0.991	0.000
Q80.8 Other congenital ichthyosis	0.008	0.991	0.000
Q80.4 Harlequin foetus	0.008	0.991	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.008	0.991	0.000
Q80.2 Lamellar ichthyosis	0.008	0.991	0.000
Q80.1 X-linked ichthyosis	0.008	0.991	0.000
Q80.0 Ichthyosis vulgaris	0.008	0.991	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.008	0.991	0.000
Q81.8 Other epidermolysis bullosa	0.008	0.991	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.008	0.991	0.000
Q81.1 Epidermolysis bullosa letalis	0.008	0.991	0.000
Q81.0 Epidermolysis bullosa simplex	0.008	0.991	0.000
Q84.9 Congenital malformation of integument, unspecified	0.008	0.991	0.000
Q84.8 Other specified congenital malformations of integument	0.008	0.991	0.000
Q84.6 Other congenital malformations of nails	0.008	0.991	0.000
Q84.5 Enlarged and hypertrophic nails	0.008	0.991	0.000
Q84.4 Congenital leukonychia	0.008	0.991	0.000
Q84.3 Anonychia	0.008	0.991	0.000
Q84.2 Other congenital malformations of hair	0.008	0.991	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.008	0.991	0.000
Q84.0 Congenital alopecia	0.008	0.991	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.008	0.991	0.000
Q86.2 Dysmorphism due to warfarin	0.008	0.991	0.000
Q86.1 Foetal hydantoin syndrome	0.008	0.991	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.008	0.991	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.008	0.991	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.008	0.992	0.000
Q45.2 Congenital pancreatic cyst	0.008	0.992	0.000
Q45.1 Annular pancreas	0.008	0.992	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.008	0.992	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.008	0.992	0.000
Q77.4 Achondroplasia	0.008	0.992	0.000
Q67.5 Congenital deformity of spine	0.008	0.992	0.000
Q78 Other osteochondrodysplasias	0.008	0.992	0.000
Q38.1 Ankyloglossia	0.008	0.992	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.008	0.992	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.008	0.992	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.008	0.992	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.008	0.992	0.000
Q06 Other congenital malformations of spinal cord	0.008	0.992	0.000
Q01 Encephalocele	0.008	0.992	0.000
Q00 Anencephaly and similar malformations	0.008	0.992	0.000
Q02 Microcephaly	0.008	0.992	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.008	0.992	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.008	0.992	0.000
Q38.6 Other congenital malformations of mouth	0.008	0.992	0.000
Q15.0 Congenital glaucoma	0.008	0.992	0.000
Q31 Congenital malformations of larynx	0.008	0.992	0.000
Q74 Other congenital malformations of limb(s)	0.008	0.992	0.000
Q39.6 Diverticulum of oesophagus	0.008	0.992	0.000
Q38.8 Other congenital malformations of pharynx	0.007	0.992	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.007	0.992	0.000
Q38.3 Other congenital malformations of tongue	0.007	0.992	0.000
Q38.2 Macroglossia	0.007	0.992	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.007	0.992	0.000
Q04.6 Congenital cerebral cysts	0.008	0.992	0.000
Q65.9 Congenital deformity of hip, unspecified	0.007	0.992	0.000
Q65.6 Unstable hip	0.007	0.992	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.007	0.992	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.007	0.992	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.007	0.992	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.007	0.992	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.007	0.992	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.007	0.992	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.007	0.992	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.007	0.992	0.000
Q77.6 Chondroectodermal dysplasia	0.007	0.992	0.000
Q77.5 Diastrophic dysplasia	0.007	0.992	0.000
Q77.3 Chondrodysplasia punctata	0.007	0.992	0.000
Q77.2 Short rib syndrome	0.007	0.992	0.000
Q77.1 Thanatophoric short stature	0.007	0.992	0.000
Q77.0 Achondrogenesis	0.007	0.992	0.000
Q34 Other congenital malformations of respiratory system	0.007	0.993	0.000
Q33 Congenital malformations of lung	0.007	0.993	0.000
Q32 Congenital malformations of trachea and bronchus	0.007	0.993	0.000
Q30 Congenital malformations of nose	0.007	0.993	0.000
Q76 Congenital malformations of spine and bony thorax	0.007	0.993	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.007	0.993	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.007	0.993	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.007	0.993	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.007	0.993	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.007	0.993	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.007	0.993	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.007	0.993	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.007	0.993	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.007	0.993	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.007	0.993	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.007	0.993	0.000
Q07.8 Other specified congenital malformations of nervous system	0.007	0.993	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.007	0.993	0.000
Q65.8 Other congenital deformities of hip	0.007	0.993	0.000
Q26 Congenital malformations of great veins	0.007	0.993	0.000
Q37 Cleft palate with cleft lip	0.007	0.993	0.000
Q36 Cleft lip	0.007	0.993	0.000
Q35 Cleft palate	0.007	0.993	0.000
Q90 Down's syndrome	0.007	0.993	0.000
Q67.8 Other congenital deformities of chest	0.007	0.993	0.000
Q67.7 Pectus carinatum	0.007	0.993	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.007	0.993	0.000
Q67.3 Plagiocephaly	0.007	0.993	0.000
Q67.2 Dolichocephaly	0.007	0.993	0.000
Q67.1 Compression facies	0.007	0.993	0.000
Q67.0 Facial asymmetry	0.007	0.993	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.007	0.993	0.000
Q79.5 Other congenital malformations of abdominal wall	0.007	0.993	0.000
Q79.4 Prune belly syndrome	0.007	0.993	0.000
Q79.3 Gastroschisis	0.007	0.993	0.000
Q79.2 Exomphalos	0.007	0.993	0.000
Q79.1 Other congenital malformations of diaphragm	0.007	0.993	0.000
Q79.0 Congenital diaphragmatic hernia	0.007	0.993	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.007	0.993	0.000
Q39.8 Other congenital malformations of oesophagus	0.007	0.993	0.000
Q39.5 Congenital dilatation of oesophagus	0.007	0.993	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.007	0.993	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.007	0.993	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.007	0.993	0.000
Q39.0 Atresia of oesophagus without fistula	0.007	0.993	0.000
Q18 Other congenital malformations of face and neck	0.007	0.993	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.007	0.993	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.007	0.993	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.007	0.993	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.007	0.993	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.007	0.993	0.000
Q15.9 Congenital malformation of eye, unspecified	0.007	0.993	0.000
Q15.8 Other specified congenital malformations of eye	0.007	0.993	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.007	0.993	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.007	0.993	0.000
Q03.8 Other congenital hydrocephalus	0.007	0.993	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.007	0.993	0.000
Q69.9 Polydactyly, unspecified	0.007	0.993	0.000
Q69.2 Accessory toe(s)	0.007	0.993	0.000
Q69.1 Accessory thumb(s)	0.007	0.993	0.000
Q69.0 Accessory finger(s)	0.007	0.993	0.000
Q70.9 Syndactyly, unspecified	0.007	0.993	0.000
Q70.4 Polysyndactyly	0.007	0.993	0.000
Q70.3 Webbed toes	0.007	0.993	0.000
Q70.2 Fused toes	0.007	0.993	0.000
Q70.1 Webbed fingers	0.007	0.993	0.000
Q70.0 Fused fingers	0.007	0.993	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.007	0.993	0.000
Q71.8 Other reduction defects of upper limb(s)	0.007	0.993	0.000
Q71.6 Lobster-claw hand	0.007	0.993	0.000
Q71.5 Longitudinal reduction defect of ulna	0.007	0.993	0.000
Q71.4 Longitudinal reduction defect of radius	0.007	0.993	0.000
Q71.3 Congenital absence of hand and finger(s)	0.007	0.993	0.000
Q71.2 Congenital absence of both forearm and hand	0.007	0.993	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.007	0.993	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.007	0.993	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.007	0.993	0.000
Q72.8 Other reduction defects of lower limb(s)	0.007	0.993	0.000
Q72.7 Split foot	0.007	0.993	0.000
Q72.6 Longitudinal reduction defect of fibula	0.007	0.993	0.000
Q72.5 Longitudinal reduction defect of tibia	0.007	0.993	0.000
Q72.4 Longitudinal reduction defect of femur	0.007	0.993	0.000
Q72.3 Congenital absence of foot and toe(s)	0.007	0.993	0.000
Q72.2 Congenital absence of both lower leg and foot	0.007	0.993	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.007	0.993	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.007	0.993	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.007	0.993	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.007	0.993	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.007	0.993	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.007	0.993	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.007	0.993	0.000
Q75.5 Oculomandibular dysostosis	0.007	0.993	0.000
Q75.4 Mandibulofacial dysostosis	0.007	0.993	0.000
Q75.3 Macrocephaly	0.007	0.993	0.000
Q75.2 Hypertelorism	0.007	0.993	0.000
Q75.1 Craniofacial dysostosis	0.007	0.993	0.000
Q75.0 Craniosynostosis	0.007	0.993	0.000
Q43.0 Meckel's diverticulum	0.007	0.993	0.000
Q04.9 Congenital malformation of brain, unspecified	0.007	0.993	0.000
Q04.8 Other specified congenital malformations of brain	0.007	0.993	0.000
Q04.5 Megalencephaly	0.007	0.993	0.000
Q04.4 Septo-optic dysplasia	0.007	0.993	0.000
Q04.3 Other reduction deformities of brain	0.007	0.993	0.000
Q04.2 Holoprosencephaly	0.007	0.993	0.000
Q04.1 Arhinencephaly	0.007	0.993	0.000
Q04.0 Congenital malformations of corpus callosum	0.007	0.993	0.000
Q79.6 Ehlers-Danlos syndrome	0.007	0.993	0.000
Q43.7 Persistent cloaca	0.007	0.993	0.000
Q43.6 Congenital fistula of rectum and anus	0.007	0.993	0.000
Q43.5 Ectopic anus	0.007	0.993	0.000
Q43.4 Duplication of intestine	0.007	0.993	0.000
Q43.2 Other congenital functional disorders of colon	0.007	0.993	0.000
Q27 Other congenital malformations of peripheral vascular system	0.007	0.993	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.006	0.993	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.006	0.993	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.006	0.993	0.000
Q11.3 Macrophthalmos	0.006	0.993	0.000
Q11.2 Microphthalmos	0.006	0.993	0.000
Q11.1 Other anophthalmos	0.006	0.993	0.000
Q11.0 Cystic eyeball	0.006	0.993	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.006	0.993	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.006	0.993	0.000
Q13.5 Blue sclera	0.006	0.993	0.000
Q13.4 Other congenital corneal malformations	0.006	0.993	0.000
Q13.3 Congenital corneal opacity	0.006	0.993	0.000
Q13.2 Other congenital malformations of iris	0.006	0.993	0.000
Q13.1 Absence of iris	0.006	0.993	0.000
Q13.0 Coloboma of iris	0.006	0.993	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.006	0.993	0.000
Q16.5 Congenital malformation of inner ear	0.006	0.993	0.000
Q16.4 Other congenital malformations of middle ear	0.006	0.993	0.000
Q16.3 Congenital malformation of ear ossicles	0.006	0.993	0.000
Q16.2 Absence of eustachian tube	0.006	0.993	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.006	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations