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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs282232
log Bayes Factor = 13.7114
Chromosome 16   position 56,597,350  (GRCh37) Explore rs282232 on Ensembl!
Variant rs282232 is part of Cluster X0051

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.996 0.004 0.000
B95-B98 Bacterial, viral and other infectious agents
0.995 0.005 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
I30-I52 Other forms of heart disease
0.987 0.013 0.000
F41 Other anxiety disorders
0.986 0.014 0.000
Chapter XIV Diseases of the genitourinary system
0.984 0.016 0.000
I20 Angina pectoris
0.982 0.018 0.000
I42 Cardiomyopathy
0.975 0.025 0.000
F41.9 Anxiety disorder, unspecified
0.973 0.027 0.000
I25 Chronic ischaemic heart disease
0.973 0.027 0.000
Chapter VIII Diseases of the ear and mastoid process
0.972 0.028 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.971 0.029 0.000
Chapter XX External causes of morbidity and mortality
0.971 0.029 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.970 0.030 0.000
I73 Other peripheral vascular diseases
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.969 0.031 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.967 0.033 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.966 0.034 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.964 0.036 0.000
I42.0 Dilated cardiomyopathy
0.961 0.039 0.000
N40-N51 Diseases of male genital organs
0.951 0.049 0.000
Chapter X Diseases of the respiratory system
0.951 0.049 0.000
I73.9 Peripheral vascular disease, unspecified
0.947 0.053 0.000
I20.0 Unstable angina
0.946 0.054 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.944 0.056 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.941 0.059 0.000
E10-E14 Diabetes mellitus
0.940 0.060 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.937 0.063 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.929 0.071 0.000
A00-A09 Intestinal infectious diseases
0.923 0.077 0.000
W00-W19 Falls
0.921 0.079 0.000
J30-J39 Other diseases of upper respiratory tract
0.920 0.080 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.919 0.081 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.914 0.086 0.000
E11 Non-insulin-dependent diabetes mellitus
0.906 0.094 0.000
I51 Complications and ill-defined descriptions of heart disease
0.900 0.100 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.896 0.104 0.000
G30-G32 Other degenerative diseases of the nervous system
0.890 0.110 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.889 0.111 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.887 0.113 0.000
H65-H75 Diseases of middle ear and mastoid
0.886 0.114 0.000
I05-I09 Chronic rheumatic heart diseases
0.885 0.115 0.000
F43 Reaction to severe stress, and adjustment disorders
0.883 0.117 0.000
E00-E07 Disorders of thyroid gland
0.882 0.118 0.000
J60-J70 Lung diseases due to external agents
0.880 0.120 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.879 0.121 0.000
Chapter XXII Codes for special purposes
0.879 0.121 0.000
N42 Other disorders of prostate
0.878 0.122 0.000
L40-L45 Papulosquamous disorders
0.873 0.127 0.000
I20.9 Angina pectoris, unspecified
0.873 0.127 0.000
N30-N39 Other diseases of urinary system
0.872 0.128 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.870 0.130 0.000
N17-N19 Renal failure
0.869 0.131 0.000
Chapter VII Diseases of the eye and adnexa
0.864 0.136 0.000
H90-H95 Other disorders of ear
0.863 0.137 0.000
N00-N08 Glomerular diseases
0.862 0.138 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.860 0.140 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.857 0.143 0.000
B35-B49 Mycoses
0.852 0.148 0.000
F45 Somatoform disorders
0.851 0.149 0.000
L20-L30 Dermatitis and eczema
0.846 0.154 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.845 0.155 0.000
N50 Other disorders of male genital organs
0.844 0.156 0.000
N48 Other disorders of penis
0.844 0.156 0.000
S60-S69 Injuries to the wrist and hand
0.842 0.158 0.000
I24 Other acute ischaemic heart diseases
0.842 0.158 0.000
J35 Chronic diseases of tonsils and adenoids
0.840 0.160 0.000
N18 Chronic renal failure
0.840 0.160 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.840 0.160 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.840 0.160 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.838 0.162 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.838 0.162 0.000
I77 Other disorders of arteries and arterioles
0.837 0.163 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.836 0.164 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.833 0.167 0.000
J69 Pneumonitis due to solids and liquids
0.833 0.167 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.832 0.168 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.832 0.168 0.000
N42.8 Other specified disorders of prostate
0.829 0.171 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.828 0.172 0.000
I38 Endocarditis, valve unspecified
0.826 0.174 0.000
F03 Unspecified dementia
0.826 0.174 0.000
F60-F69 Disorders of adult personality and behaviour
0.822 0.178 0.000
I51.9 Heart disease, unspecified
0.818 0.182 0.000
N60-N64 Disorders of breast
0.817 0.183 0.000
W19 Unspecified fall
0.811 0.189 0.000
Chapter XI Diseases of the digestive system
0.809 0.191 0.000
E10 Insulin-dependent diabetes mellitus
0.807 0.193 0.000
I70 Atherosclerosis
0.807 0.193 0.000
L03 Cellulitis
0.806 0.194 0.000
N50.1 Vascular disorders of male genital organs
0.806 0.194 0.000
N35 Urethral stricture
0.806 0.194 0.000
I22 Subsequent myocardial infarction
0.806 0.194 0.000
J33 Nasal polyp
0.805 0.195 0.000
F00 Dementia in Alzheimer's disease
0.804 0.195 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.804 0.196 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.800 0.200 0.000
J69.0 Pneumonitis due to food and vomit
0.800 0.200 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.797 0.203 0.000
G51 Facial nerve disorders
0.797 0.203 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.797 0.203 0.000
I25.5 Ischaemic cardiomyopathy
0.796 0.204 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.795 0.205 0.000
E40-E46 Malnutrition
0.794 0.206 0.000
F02 Dementia in other diseases classified elsewhere
0.794 0.206 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.793 0.207 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.793 0.207 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.792 0.208 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.789 0.211 0.000
N18.3 Chronic kidney disease, stage 3
0.788 0.212 0.000
E11.2 With renal complications
0.787 0.213 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.787 0.213 0.000
I20.8 Other forms of angina pectoris
0.787 0.213 0.000
I33 Acute and subacute endocarditis
0.786 0.214 0.000
I42.9 Cardiomyopathy, unspecified
0.784 0.216 0.000
E03 Other hypothyroidism
0.784 0.216 0.000
Chapter XXI Factors influencing health status and contact with health services
0.784 0.216 0.000
T79-T79 Certain early complications of trauma
0.784 0.216 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.783 0.217 0.000
I74 Arterial embolism and thrombosis
0.783 0.217 0.000
H80-H83 Diseases of inner ear
0.780 0.220 0.000
I25.4 Coronary artery aneurysm
0.779 0.220 0.000
G30 Alzheimer's disease
0.778 0.222 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.777 0.223 0.000
F30-F39 Mood [affective] disorders
0.777 0.223 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.775 0.225 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.773 0.226 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.773 0.227 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.770 0.229 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.770 0.229 0.000
I34 Nonrheumatic mitral valve disorders
0.770 0.230 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.770 0.230 0.000
I72 Other aneurysm
0.770 0.230 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.767 0.233 0.000
I73.0 Raynaud's syndrome
0.767 0.233 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.765 0.235 0.000
W06 Fall involving bed
0.763 0.237 0.000
I37 Pulmonary valve disorders
0.763 0.237 0.000
J00-J06 Acute upper respiratory infections
0.763 0.237 0.000
X60-X84 Intentional self-harm
0.762 0.238 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.761 0.238 0.000
I05 Rheumatic mitral valve diseases
0.761 0.239 0.000
J32 Chronic sinusitis
0.761 0.239 0.000
I07 Rheumatic tricuspid valve diseases
0.760 0.240 0.000
E11.3 With ophthalmic complications
0.759 0.241 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.758 0.242 0.000
W07 Fall involving chair
0.757 0.243 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.754 0.246 0.000
L40 Psoriasis
0.754 0.246 0.000
G59.0 Diabetic mononeuropathy
0.751 0.249 0.000
K70-K77 Diseases of liver
0.751 0.249 0.000
N03 Chronic nephritic syndrome
0.750 0.250 0.000
K04 Diseases of pulp and periapical tissues
0.750 0.250 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.748 0.252 0.000
H91 Other hearing loss
0.747 0.253 0.000
F45.8 Other somatoform disorders
0.747 0.253 0.000
V20-V29 Motorcycle rider injured in transport accident
0.746 0.254 0.000
L08 Other local infections of skin and subcutaneous tissue
0.746 0.254 0.000
S40-S49 Injuries to the shoulder and upper arm
0.745 0.254 0.000
H66 Suppurative and unspecified otitis media
0.745 0.255 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.745 0.255 0.000
E11.8 With unspecified complications
0.745 0.255 0.000
I45 Other conduction disorders
0.744 0.256 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.744 0.256 0.000
S70-S79 Injuries to the hip and thigh
0.744 0.256 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.744 0.256 0.000
Y00-Y09 Assault
0.742 0.258 0.000
H70 Mastoiditis and related conditions
0.741 0.259 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.741 0.259 0.000
I24.8 Other forms of acute ischaemic heart disease
0.741 0.259 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.741 0.259 0.000
G70-G73 Diseases of myoneural junction and muscle
0.739 0.261 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.736 0.264 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.735 0.265 0.000
N35.9 Urethral stricture, unspecified
0.735 0.265 0.000
L50-L54 Urticaria and erythema
0.734 0.266 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.734 0.266 0.000
B15-B19 Viral hepatitis
0.733 0.267 0.000
N36 Other disorders of urethra
0.733 0.267 0.000
I42.2 Other hypertrophic cardiomyopathy
0.733 0.267 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.732 0.268 0.000
H60-H62 Diseases of external ear
0.732 0.268 0.000
S60 Superficial injury of wrist and hand
0.732 0.268 0.000
N48.1 Balanoposthitis
0.731 0.269 0.000
E11.9 Without complications
0.731 0.269 0.000
F43.0 Acute stress reaction
0.730 0.270 0.000
M05-M14 Inflammatory polyarthropathies
0.729 0.271 0.000
L43 Lichen planus
0.729 0.271 0.000
A08 Viral and other specified intestinal infections
0.728 0.272 0.000
E16 Other disorders of pancreatic internal secretion
0.727 0.273 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.726 0.274 0.000
N61 Inflammatory disorders of breast
0.726 0.274 0.000
F40 Phobic anxiety disorders
0.723 0.277 0.000
H74 Other disorders of middle ear and mastoid
0.721 0.279 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.721 0.279 0.000
Y40 Systemic antibiotics
0.720 0.280 0.000
H73 Other disorders of tympanic membrane
0.719 0.281 0.000
Y44 Agents primarily affecting blood constituents
0.718 0.282 0.000
L29 Pruritus
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
B37 Candidiasis
0.717 0.283 0.000
I77.6 Arteritis, unspecified
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
G50 Disorders of trigeminal nerve
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
G54 Nerve root and plexus disorders
0.715 0.285 0.000
F48 Other neurotic disorders
0.714 0.286 0.000
F44 Dissociative [conversion] disorders
0.714 0.286 0.000
F42 Obsessive-compulsive disorder
0.714 0.286 0.000
E03.9 Hypothyroidism, unspecified
0.714 0.286 0.000
I71 Aortic aneurysm and dissection
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
H92 Otalgia and effusion of ear
0.712 0.288 0.000
S90-S99 Injuries to the ankle and foot
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
J38.2 Nodules of vocal cords
0.708 0.292 0.000
L03.1 Cellulitis of other parts of limb
0.708 0.292 0.000
H52 Disorders of refraction and accommodation
0.708 0.292 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
I51.6 Cardiovascular disease, unspecified
0.707 0.293 0.000
E06 Thyroiditis
0.707 0.293 0.000
K04.7 Periapical abscess without sinus
0.707 0.293 0.000
F41.8 Other specified anxiety disorders
0.707 0.293 0.000
F41.3 Other mixed anxiety disorders
0.707 0.293 0.000
N42.2 Atrophy of prostate
0.707 0.293 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.706 0.293 0.000
F99-F99 Unspecified mental disorder
0.706 0.294 0.000
H25-H28 Disorders of lens
0.706 0.294 0.000
M70-M79 Other soft tissue disorders
0.704 0.296 0.000
A30-A49 Other bacterial diseases
0.704 0.296 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.704 0.296 0.000
E11.5 With peripheral circulatory complications
0.704 0.296 0.000
H69 Other disorders of Eustachian tube
0.703 0.297 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.703 0.297 0.000
H50 Other strabismus
0.703 0.297 0.000
S62 Fracture at wrist and hand level
0.702 0.298 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.702 0.298 0.000
F43.2 Adjustment disorders
0.702 0.298 0.000
F43.1 Posttraumatic stress disorder
0.701 0.299 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.699 0.300 0.000
I42.8 Other cardiomyopathies
0.699 0.301 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.699 0.301 0.000
I42.6 Alcoholic cardiomyopathy
0.699 0.301 0.000
I42.5 Other restrictive cardiomyopathy
0.699 0.301 0.000
I42.4 Endocardial fibroelastosis
0.699 0.301 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.699 0.301 0.000
G30.9 Alzheimer's disease, unspecified
0.698 0.302 0.000
I25.6 Silent myocardial ischaemia
0.697 0.303 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.697 0.303 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.697 0.303 0.000
G56 Mononeuropathies of upper limb
0.696 0.304 0.000
L10-L14 Bullous disorders
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.304 0.000
X50-X57 Overexertion, travel and privation
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V80-V89 Other land transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.695 0.305 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.695 0.305 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.695 0.305 0.000
I73.8 Other specified peripheral vascular diseases
0.695 0.305 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.695 0.305 0.000
F60 Specific personality disorders
0.695 0.305 0.000
N48.4 Impotence of organic origin
0.695 0.305 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
W19.2 School, other institution and public administrative area
0.695 0.305 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.694 0.306 0.000
W18 Other fall on same level
0.694 0.306 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.693 0.307 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.693 0.307 0.000
G90-G99 Other disorders of the nervous system
0.692 0.308 0.000
T33-T35 Frostbite
0.692 0.308 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.692 0.308 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.692 0.308 0.000
T00-T07 Injuries involving multiple body regions
0.692 0.308 0.000
G58 Other mononeuropathies
0.691 0.309 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.691 0.309 0.000
G52 Disorders of other cranial nerves
0.691 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.689 0.311 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.689 0.311 0.000
F01 Vascular dementia
0.688 0.311 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.688 0.312 0.000
Y52 Agents primarily affecting the cardiovascular system
0.688 0.312 0.000
U89 Agent resistant to other and unspecified antibiotics
0.688 0.312 0.000
E10.3 With ophthalmic complications
0.688 0.312 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.687 0.312 0.000
I44 Atrioventricular and left bundle-branch block
0.687 0.313 0.000
N18.8 Other chronic renal failure
0.686 0.314 0.000
K01 Embedded and impacted teeth
0.686 0.314 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.685 0.315 0.000
J38.7 Other diseases of larynx
0.685 0.315 0.000
I25.3 Aneurysm of heart
0.684 0.315 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.684 0.316 0.000
W10 Fall on and from stairs and steps
0.683 0.317 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.682 0.318 0.000
N46 Male infertility
0.682 0.318 0.000
N44 Torsion of testis
0.682 0.318 0.000
E20-E35 Disorders of other endocrine glands
0.682 0.318 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.681 0.318 0.000
K74 Fibrosis and cirrhosis of liver
0.681 0.319 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.679 0.321 0.000
J40-J47 Chronic lower respiratory diseases
0.679 0.321 0.000
K50-K52 Noninfective enteritis and colitis
0.679 0.321 0.000
G51.0 Bell's palsy
0.678 0.322 0.000
N48.0 Leukoplakia of penis
0.678 0.322 0.000
J38.5 Laryngeal spasm
0.677 0.323 0.000
G40-G47 Episodic and paroxysmal disorders
0.677 0.323 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.675 0.325 0.000
F09 Unspecified organic or symptomatic mental disorder
0.675 0.325 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.675 0.325 0.000
E12 Malnutrition-related diabetes mellitus
0.674 0.326 0.000
H55-H59 Other disorders of eye and adnexa
0.672 0.328 0.000
I07.1 Tricuspid insufficiency
0.671 0.329 0.000
I20.1 Angina pectoris with documented spasm
0.671 0.329 0.000
H52.2 Astigmatism
0.670 0.330 0.000
N03.9 Unspecified
0.670 0.330 0.000
T86 Failure and rejection of transplanted organs and tissues
0.669 0.331 0.000
E46 Unspecified protein-energy malnutrition
0.668 0.332 0.000
I51.7 Cardiomegaly
0.667 0.333 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
L04 Acute lymphadenitis
0.666 0.334 0.000
L01 Impetigo
0.666 0.334 0.000
L00 Staphylococcal scalded skin syndrome
0.666 0.334 0.000
J33.0 Polyp of nasal cavity
0.666 0.334 0.000
I30 Acute pericarditis
0.666 0.334 0.000
B44 Aspergillosis
0.665 0.335 0.000
H91.9 Hearing loss, unspecified
0.664 0.336 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.664 0.336 0.000
S20-S29 Injuries to the thorax
0.664 0.336 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.663 0.337 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.662 0.338 0.000
A07 Other protozoal intestinal diseases
0.662 0.338 0.000
A06 Amoebiasis
0.662 0.338 0.000
A05 Other bacterial foodborne intoxications
0.662 0.338 0.000
A03 Shigellosis
0.662 0.338 0.000
A02 Other Salmonella infections
0.662 0.338 0.000
A01 Typhoid and paratyphoid fevers
0.662 0.338 0.000
A00 Cholera
0.662 0.338 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.662 0.338 0.000
W17 Other fall from one level to another
0.660 0.339 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.660 0.339 0.000
W15 Fall from cliff
0.660 0.339 0.000
W14 Fall from tree
0.660 0.339 0.000
W12 Fall on and from scaffolding
0.660 0.339 0.000
W11 Fall on and from ladder
0.660 0.339 0.000
W09 Fall involving playground equipment
0.660 0.339 0.000
W08 Fall involving other furniture
0.660 0.339 0.000
W05 Fall involving wheelchair
0.660 0.339 0.000
W04 Fall while being carried or supported by other persons
0.660 0.339 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.660 0.339 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.660 0.339 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.660 0.339 0.000
W00 Fall on same level involving ice and snow
0.660 0.339 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.660 0.340 0.000
G12 Spinal muscular atrophy and related syndromes
0.660 0.340 0.000
M80-M85 Disorders of bone density and structure
0.660 0.340 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.660 0.340 0.000
J37 Chronic laryngitis and laryngotracheitis
0.659 0.340 0.000
M10 Gout
0.659 0.341 0.000
T87 Complications peculiar to reattachment and amputation
0.658 0.341 0.000
N70 Salpingitis and oophoritis
0.658 0.342 0.000
J40 Bronchitis, not specified as acute or chronic
0.658 0.342 0.000
L27 Dermatitis due to substances taken internally
0.657 0.343 0.000
N71 Inflammatory disease of uterus, except cervix
0.657 0.343 0.000
N36.8 Other specified disorders of urethra
0.657 0.343 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.656 0.344 0.000
L05 Pilonidal cyst
0.656 0.344 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.655 0.345 0.000
K13 Other diseases of lip and oral mucosa
0.655 0.345 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.655 0.345 0.000
K05 Gingivitis and periodontal diseases
0.655 0.345 0.000
J35.1 Hypertrophy of tonsils
0.654 0.346 0.000
E16.2 Hypoglycaemia, unspecified
0.654 0.346 0.000
N35.8 Other urethral stricture
0.654 0.346 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.653 0.347 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.653 0.347 0.000
I05.0 Mitral stenosis
0.653 0.347 0.000
N64 Other disorders of breast
0.652 0.348 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.652 0.348 0.000
K75 Other inflammatory liver diseases
0.651 0.349 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.651 0.349 0.000
I45.6 Preexcitation syndrome
0.651 0.349 0.000
N75 Diseases of Bartholin's gland
0.651 0.349 0.000
N76 Other inflammation of vagina and vulva
0.650 0.350 0.000
W06.0 Home
0.650 0.350 0.000
T93 Sequelae of injuries of lower limb
0.650 0.350 0.000
M65-M68 Disorders of synovium and tendon
0.650 0.350 0.000
E14 Unspecified diabetes mellitus
0.650 0.350 0.000
E11.7 With multiple complications
0.649 0.350 0.000
E11.6 With other specified complications
0.649 0.350 0.000
E11.1 With ketoacidosis
0.649 0.350 0.000
E11.0 With coma
0.649 0.350 0.000
J86 Pyothorax
0.649 0.351 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.649 0.351 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.648 0.352 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.647 0.353 0.000
K02 Dental caries
0.647 0.353 0.000
J33.9 Nasal polyp, unspecified
0.646 0.354 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.646 0.354 0.000
N20-N23 Urolithiasis
0.646 0.354 0.000
J31.0 Chronic rhinitis
0.646 0.354 0.000
W19.4 Street and highway
0.646 0.354 0.000
I51.5 Myocardial degeneration
0.645 0.355 0.000
I51.4 Myocarditis, unspecified
0.645 0.355 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.645 0.355 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.645 0.355 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.645 0.355 0.000
I51.0 Cardiac septal defect, acquired
0.645 0.355 0.000
I44.7 Left bundle-branch block, unspecified
0.645 0.355 0.000
F41.1 Generalised anxiety disorder
0.645 0.355 0.000
T66-T78 Other and unspecified effects of external causes
0.644 0.355 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.644 0.356 0.000
I34.0 Mitral (valve) insufficiency
0.644 0.356 0.000
W13 Fall from, out of or through building or structure
0.644 0.356 0.000
Z80 Family history of malignant neoplasm
0.644 0.356 0.000
N18.5 Chronic kidney disease, stage 5
0.644 0.356 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.644 0.356 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.643 0.357 0.000
W19.3 Sports and athletics area
0.643 0.357 0.000
I33.0 Acute and subacute infective endocarditis
0.642 0.358 0.000
Q60-Q64 Congenital malformations of the urinary system
0.640 0.360 0.000
W07.0 Home
0.640 0.360 0.000
H80 Otosclerosis
0.639 0.361 0.000
S60.8 Other superficial injuries of wrist and hand
0.639 0.361 0.000
N18.0 End-stage renal disease
0.638 0.362 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.638 0.362 0.000
J32.9 Chronic sinusitis, unspecified
0.638 0.362 0.000
H70.9 Mastoiditis, unspecified
0.637 0.363 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.636 0.364 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.636 0.364 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.635 0.364 0.000
H68 Eustachian salpingitis and obstruction
0.635 0.364 0.000
H67 Otitis media in diseases classified elsewhere
0.635 0.364 0.000
L03.0 Cellulitis of finger and toe
0.635 0.365 0.000
U89.8 Agent resistant to other single specified antibiotic
0.635 0.365 0.000
L40.5 Arthropathic psoriasis
0.635 0.365 0.000
K09 Cysts of oral region, not elsewhere classified
0.634 0.365 0.000
I09 Other rheumatic heart diseases
0.634 0.366 0.000
I06 Rheumatic aortic valve diseases
0.634 0.366 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.634 0.366 0.000
H25 Senile cataract
0.634 0.366 0.000
N62 Hypertrophy of breast
0.634 0.366 0.000
E13 Other specified diabetes mellitus
0.633 0.366 0.000
F43.9 Reaction to severe stress, unspecified
0.633 0.367 0.000
F43.8 Other reactions to severe stress
0.633 0.367 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.633 0.367 0.000
E11.4 With neurological complications
0.633 0.367 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.633 0.367 0.000
W20-W49 Exposure to inanimate mechanical forces
0.633 0.367 0.000
I77.8 Other specified disorders of arteries and arterioles
0.632 0.368 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.632 0.368 0.000
E00 Congenital iodine-deficiency syndrome
0.632 0.368 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.632 0.368 0.000
J36 Peritonsillar abscess
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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