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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2823752
log Bayes Factor = 12.8636
Chromosome 21   position 17,717,125  (GRCh37) Explore rs2823752 on Ensembl!
Variant rs2823752 is part of Cluster X0132

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
N40-N51 Diseases of male genital organs
0.999 0.001 0.000
Chapter II Neoplasms
0.997 0.003 0.000
N40 Hyperplasia of prostate
0.997 0.003 0.000
N95 Menopausal and other perimenopausal disorders
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.977 0.023 0.000
Chapter I Certain infectious and parasitic diseases
0.969 0.031 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.967 0.033 0.000
Chapter VIII Diseases of the ear and mastoid process
0.961 0.039 0.000
B95-B98 Bacterial, viral and other infectious agents
0.960 0.040 0.000
Chapter VII Diseases of the eye and adnexa
0.959 0.041 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.959 0.041 0.000
C15-C26 Malignant neoplasms of digestive organs
0.956 0.044 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.955 0.045 0.000
N10-N16 Renal tubulo-interstitial diseases
0.951 0.049 0.000
G40-G47 Episodic and paroxysmal disorders
0.945 0.055 0.000
N95.0 Postmenopausal bleeding
0.945 0.055 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.940 0.060 0.000
G40 Epilepsy
0.938 0.062 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.933 0.067 0.000
F60-F69 Disorders of adult personality and behaviour
0.925 0.075 0.000
N13 Obstructive and reflux uropathy
0.924 0.076 0.000
N50 Other disorders of male genital organs
0.924 0.076 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.923 0.077 0.000
H30-H36 Disorders of choroid and retina
0.920 0.080 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.919 0.081 0.000
C64-C68 Malignant neoplasms of urinary tract
0.913 0.087 0.000
F30-F39 Mood [affective] disorders
0.912 0.088 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.912 0.088 0.000
G40.9 Epilepsy, unspecified
0.912 0.088 0.000
H90-H95 Other disorders of ear
0.910 0.090 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.910 0.090 0.000
D10-D36 Benign neoplasms
0.909 0.091 0.000
N93 Other abnormal uterine and vaginal bleeding
0.908 0.092 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.907 0.093 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.907 0.093 0.000
N81 Female genital prolapse
0.897 0.103 0.000
N95.2 Postmenopausal atrophic vaginitis
0.893 0.107 0.000
N13.3 Other and unspecified hydronephrosis
0.891 0.109 0.000
D70 Agranulocytosis
0.890 0.110 0.000
F60 Specific personality disorders
0.875 0.125 0.000
D18 Haemangioma and lymphangioma, any site
0.874 0.126 0.000
S80-S89 Injuries to the knee and lower leg
0.869 0.131 0.000
N85.4 Malposition of uterus
0.866 0.134 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.865 0.135 0.000
G20-G26 Extrapyramidal and movement disorders
0.864 0.136 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.862 0.138 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.859 0.141 0.000
N81.2 Incomplete uterovaginal prolapse
0.858 0.142 0.000
C18 Malignant neoplasm of colon
0.858 0.142 0.000
H90 Conductive and sensorineural hearing loss
0.858 0.142 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.850 0.150 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.849 0.151 0.000
D18.0 Haemangioma, any site
0.849 0.151 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.846 0.154 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.845 0.155 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.844 0.156 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.843 0.157 0.000
N17-N19 Renal failure
0.843 0.157 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.843 0.157 0.000
N30-N39 Other diseases of urinary system
0.843 0.157 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.838 0.162 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.833 0.167 0.000
S20-S29 Injuries to the thorax
0.830 0.170 0.000
T66-T78 Other and unspecified effects of external causes
0.829 0.171 0.000
N82 Fistulae involving female genital tract
0.828 0.172 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.825 0.175 0.000
D34 Benign neoplasm of thyroid gland
0.825 0.175 0.000
F31 Bipolar affective disorder
0.825 0.175 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.822 0.178 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.818 0.182 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
C67 Malignant neoplasm of bladder
0.812 0.188 0.000
O60-O75 Complications of labour and delivery
0.811 0.189 0.000
N95.3 States associated with artificial menopause
0.809 0.191 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.808 0.192 0.000
F60.9 Personality disorder, unspecified
0.806 0.194 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.794 0.206 0.000
N42 Other disorders of prostate
0.793 0.207 0.000
G70-G73 Diseases of myoneural junction and muscle
0.790 0.210 0.000
H36 Retinal disorders in diseases classified elsewhere
0.789 0.211 0.000
D60-D64 Aplastic and other anaemias
0.786 0.214 0.000
N36 Other disorders of urethra
0.786 0.214 0.000
D80-D89 Certain disorders involving the immune mechanism
0.786 0.214 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.786 0.214 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.785 0.215 0.000
F80-F89 Disorders of psychological development
0.784 0.216 0.000
S70-S79 Injuries to the hip and thigh
0.784 0.216 0.000
N93.0 Postcoital and contact bleeding
0.784 0.216 0.000
H55-H59 Other disorders of eye and adnexa
0.783 0.217 0.000
N50.8 Other specified disorders of male genital organs
0.783 0.217 0.000
N88 Other noninflammatory disorders of cervix uteri
0.782 0.218 0.000
D45 Polycythaemia vera
0.782 0.218 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.780 0.220 0.000
Chapter XX External causes of morbidity and mortality
0.780 0.220 0.000
G40.8 Other epilepsy
0.779 0.220 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.779 0.221 0.000
G90-G99 Other disorders of the nervous system
0.777 0.223 0.000
H60-H62 Diseases of external ear
0.776 0.224 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.776 0.224 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.776 0.224 0.000
H35 Other retinal disorders
0.775 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.226 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.771 0.229 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.771 0.229 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.770 0.230 0.000
Chapter XXII Codes for special purposes
0.769 0.231 0.000
N85.2 Hypertrophy of uterus
0.769 0.231 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.769 0.231 0.000
N45 Orchitis and epididymitis
0.768 0.231 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.768 0.232 0.000
O70 Perineal laceration during delivery
0.768 0.232 0.000
F22 Persistent delusional disorders
0.767 0.233 0.000
F43 Reaction to severe stress, and adjustment disorders
0.766 0.234 0.000
F29 Unspecified nonorganic psychosis
0.765 0.235 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.763 0.237 0.000
N81.5 Vaginal enterocele
0.763 0.237 0.000
D73 Diseases of spleen
0.762 0.238 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.761 0.239 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.760 0.240 0.000
H90.2 Conductive hearing loss, unspecified
0.759 0.240 0.000
N50.0 Atrophy of testis
0.759 0.240 0.000
H34 Retinal vascular occlusions
0.759 0.241 0.000
O70.0 First degree perineal laceration during delivery
0.758 0.242 0.000
N60-N64 Disorders of breast
0.758 0.242 0.000
T79-T79 Certain early complications of trauma
0.758 0.242 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.757 0.243 0.000
H33 Retinal detachments and breaks
0.757 0.243 0.000
O80-O84 Delivery
0.757 0.243 0.000
N89 Other noninflammatory disorders of vagina
0.756 0.244 0.000
D75 Other diseases of blood and blood-forming organs
0.756 0.244 0.000
A80-A89 Viral infections of the central nervous system
0.754 0.246 0.000
N32 Other disorders of bladder
0.754 0.246 0.000
N50.9 Disorder of male genital organs, unspecified
0.753 0.247 0.000
D23 Other benign neoplasms of skin
0.753 0.247 0.000
C91 Lymphoid leukaemia
0.753 0.247 0.000
C18.0 Caecum
0.753 0.247 0.000
N85.1 Endometrial adenomatous hyperplasia
0.752 0.248 0.000
D10 Benign neoplasm of mouth and pharynx
0.751 0.248 0.000
S10-S19 Injuries to the neck
0.749 0.251 0.000
D16 Benign neoplasm of bone and articular cartilage
0.749 0.251 0.000
G25 Other extrapyramidal and movement disorders
0.748 0.252 0.000
H80-H83 Diseases of inner ear
0.748 0.252 0.000
N84 Polyp of female genital tract
0.747 0.253 0.000
F60.3 Emotionally unstable personality disorder
0.747 0.253 0.000
H91 Other hearing loss
0.742 0.258 0.000
H43-H45 Disorders of vitreous body and globe
0.739 0.261 0.000
N81.4 Uterovaginal prolapse, unspecified
0.739 0.261 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.738 0.262 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.737 0.263 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.736 0.264 0.000
S82 Fracture of lower leg, including ankle
0.736 0.264 0.000
N43 Hydrocele and spermatocele
0.734 0.266 0.000
Chapter XXI Factors influencing health status and contact with health services
0.733 0.267 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.732 0.268 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.730 0.270 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.729 0.271 0.000
C67.2 Lateral wall of bladder
0.728 0.272 0.000
N86 Erosion and ectropion of cervix uteri
0.728 0.272 0.000
N13.6 Pyonephrosis
0.727 0.273 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.726 0.274 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.725 0.275 0.000
D46 Myelodysplastic syndromes
0.724 0.276 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.724 0.276 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.723 0.277 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.722 0.278 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.722 0.278 0.000
G41 Status epilepticus
0.722 0.278 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.721 0.279 0.000
H18 Other disorders of cornea
0.721 0.279 0.000
S32 Fracture of lumbar spine and pelvis
0.721 0.279 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.719 0.281 0.000
D26 Other benign neoplasms of uterus
0.718 0.282 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
H90.5 Sensorineural hearing loss, unspecified
0.717 0.283 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.716 0.284 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.716 0.284 0.000
N46 Male infertility
0.716 0.284 0.000
N44 Torsion of testis
0.716 0.284 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.715 0.285 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.286 0.000
D29 Benign neoplasm of male genital organs
0.713 0.287 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.712 0.288 0.000
H33.0 Retinal detachment with retinal break
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
F32 Depressive episode
0.712 0.288 0.000
N32.8 Other specified disorders of bladder
0.710 0.290 0.000
F31.9 Bipolar affective disorder, unspecified
0.710 0.290 0.000
T78 Adverse effects, not elsewhere classified
0.710 0.290 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.709 0.291 0.000
F10.1 Harmful use
0.709 0.291 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.708 0.291 0.000
N85.7 Haematometra
0.708 0.292 0.000
N85.6 Intra-uterine synechiae
0.708 0.292 0.000
N85.5 Inversion of uterus
0.708 0.292 0.000
N85.3 Subinvolution of uterus
0.708 0.292 0.000
G81 Hemiplegia
0.708 0.292 0.000
B25-B34 Other viral diseases
0.708 0.292 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.707 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.707 0.292 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.706 0.293 0.000
N82.0 Vesicovaginal fistula
0.706 0.294 0.000
C92 Myeloid leukaemia
0.705 0.295 0.000
C83.1 Small cleaved cell (diffuse)
0.705 0.295 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.703 0.297 0.000
T39.1 4-Aminophenol derivatives
0.703 0.297 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.703 0.297 0.000
D11 Benign neoplasm of major salivary glands
0.702 0.298 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.702 0.298 0.000
F23 Acute and transient psychotic disorders
0.701 0.298 0.000
N19 Unspecified renal failure
0.701 0.299 0.000
C18.3 Hepatic flexure
0.701 0.299 0.000
N95.1 Menopausal and female climacteric states
0.700 0.300 0.000
N36.8 Other specified disorders of urethra
0.699 0.301 0.000
C18.5 Splenic flexure
0.699 0.301 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.699 0.301 0.000
N11 Chronic tubulo-interstitial nephritis
0.697 0.303 0.000
C83.0 Small cell (diffuse)
0.696 0.304 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.305 0.000
B65-B83 Helminthiases
0.695 0.305 0.000
B50-B64 Protozoal diseases
0.695 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.305 0.000
A75-A79 Rickettsioses
0.695 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.305 0.000
A65-A69 Other spirochaetal diseases
0.695 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.305 0.000
A15-A19 Tuberculosis
0.695 0.305 0.000
H36.0 Diabetic retinopathy
0.695 0.305 0.000
D55-D59 Haemolytic anaemias
0.693 0.307 0.000
N60 Benign mammary dysplasia
0.693 0.307 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.693 0.307 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.693 0.307 0.000
C18.4 Transverse colon
0.690 0.310 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.690 0.310 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.690 0.310 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.688 0.312 0.000
O80 Single spontaneous delivery
0.688 0.312 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.687 0.313 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.313 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.687 0.313 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.687 0.313 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.687 0.313 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.687 0.313 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.687 0.313 0.000
T36 Poisoning by systemic antibiotics
0.687 0.313 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.687 0.313 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.685 0.314 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.685 0.314 0.000
C21 Malignant neoplasm of anus and anal canal
0.685 0.314 0.000
C17 Malignant neoplasm of small intestine
0.685 0.314 0.000
C23 Malignant neoplasm of gallbladder
0.685 0.314 0.000
C25 Malignant neoplasm of pancreas
0.685 0.315 0.000
N18 Chronic renal failure
0.685 0.315 0.000
B15-B19 Viral hepatitis
0.685 0.315 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.685 0.315 0.000
C95 Leukaemia of unspecified cell type
0.685 0.315 0.000
C94 Other leukaemias of specified cell type
0.685 0.315 0.000
C93 Monocytic leukaemia
0.685 0.315 0.000
C88 Malignant immunoproliferative diseases
0.685 0.315 0.000
C86 Other specified types of T/NK-cell lymphoma
0.685 0.315 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.685 0.315 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.684 0.316 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.684 0.316 0.000
F33 Recurrent depressive disorder
0.684 0.316 0.000
G20 Parkinson's disease
0.683 0.317 0.000
G83 Other paralytic syndromes
0.683 0.317 0.000
F20 Schizophrenia
0.682 0.318 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.682 0.318 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.682 0.318 0.000
N15 Other renal tubulo-interstitial diseases
0.682 0.318 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.682 0.318 0.000
N42.1 Congestion and haemorrhage of prostate
0.680 0.320 0.000
H65-H75 Diseases of middle ear and mastoid
0.680 0.320 0.000
N50.1 Vascular disorders of male genital organs
0.679 0.321 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.679 0.321 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.679 0.321 0.000
N13.4 Hydroureter
0.679 0.321 0.000
N00-N08 Glomerular diseases
0.679 0.321 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.678 0.322 0.000
H93 Other disorders of ear, not elsewhere classified
0.678 0.322 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.677 0.323 0.000
D69 Purpura and other haemorrhagic conditions
0.677 0.323 0.000
Chapter X Diseases of the respiratory system
0.676 0.324 0.000
D64 Other anaemias
0.675 0.325 0.000
T51 Toxic effect of alcohol
0.674 0.326 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.673 0.327 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.672 0.328 0.000
G40.5 Special epileptic syndromes
0.672 0.328 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.672 0.328 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.672 0.328 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.672 0.328 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.672 0.328 0.000
C81 Hodgkin's disease
0.671 0.329 0.000
D23.0 Skin of lip
0.671 0.329 0.000
C15 Malignant neoplasm of oesophagus
0.670 0.329 0.000
S40-S49 Injuries to the shoulder and upper arm
0.670 0.330 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.669 0.331 0.000
D74 Methaemoglobinaemia
0.669 0.331 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.669 0.331 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.669 0.331 0.000
N80 Endometriosis
0.669 0.331 0.000
G44 Other headache syndromes
0.669 0.331 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.668 0.332 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.667 0.333 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.666 0.334 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.666 0.334 0.000
C01 Malignant neoplasm of base of tongue
0.666 0.334 0.000
F99-F99 Unspecified mental disorder
0.665 0.334 0.000
C83.3 Large cell (diffuse)
0.664 0.336 0.000
F43.2 Adjustment disorders
0.664 0.336 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.664 0.336 0.000
F68 Other disorders of adult personality and behaviour
0.663 0.336 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.663 0.336 0.000
F65 Disorders of sexual preference
0.663 0.336 0.000
F64 Gender identity disorders
0.663 0.336 0.000
F63 Habit and impulse disorders
0.663 0.336 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.663 0.336 0.000
F69 Unspecified disorder of adult personality and behaviour
0.663 0.336 0.000
F61 Mixed and other personality disorders
0.663 0.336 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.663 0.337 0.000
S80 Superficial injury of lower leg
0.663 0.337 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.663 0.337 0.000
F22.0 Delusional disorder
0.662 0.337 0.000
Q80-Q89 Other congenital malformations
0.662 0.338 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.662 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.662 0.338 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.662 0.338 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.662 0.338 0.000
A30-A49 Other bacterial diseases
0.662 0.338 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.662 0.338 0.000
H25-H28 Disorders of lens
0.661 0.339 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.659 0.340 0.000
H31 Other disorders of choroid
0.659 0.340 0.000
H30 Chorioretinal inflammation
0.659 0.340 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.659 0.341 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.659 0.341 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.659 0.341 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.659 0.341 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.659 0.341 0.000
H81 Disorders of vestibular function
0.659 0.341 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.656 0.344 0.000
S82.1 Fracture of upper end of tibia
0.655 0.344 0.000
S50-S59 Injuries to the elbow and forearm
0.655 0.345 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.655 0.345 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.654 0.346 0.000
C66 Malignant neoplasm of ureter
0.654 0.346 0.000
C65 Malignant neoplasm of renal pelvis
0.654 0.346 0.000
F38 Other mood [affective] disorders
0.654 0.346 0.000
F34 Persistent mood [affective] disorders
0.654 0.346 0.000
F30 Manic episode
0.654 0.346 0.000
F39 Unspecified mood [affective] disorder
0.654 0.346 0.000
F25 Schizoaffective disorders
0.654 0.346 0.000
F28 Other nonorganic psychotic disorders
0.654 0.346 0.000
F24 Induced delusional disorder
0.654 0.346 0.000
F21 Schizotypal disorder
0.654 0.346 0.000
N99-N99 Other disorders of the genitourinary system
0.653 0.347 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.653 0.347 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.653 0.347 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.653 0.347 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.652 0.348 0.000
D31 Benign neoplasm of eye and adnexa
0.651 0.348 0.000
D30 Benign neoplasm of urinary organs
0.651 0.348 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.651 0.348 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.651 0.348 0.000
D19 Benign neoplasm of mesothelial tissue
0.651 0.348 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.651 0.348 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.651 0.348 0.000
N25-N29 Other disorders of kidney and ureter
0.651 0.348 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.651 0.349 0.000
H21 Other disorders of iris and ciliary body
0.651 0.349 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.650 0.350 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.649 0.350 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.648 0.352 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.648 0.352 0.000
C20 Malignant neoplasm of rectum
0.646 0.354 0.000
G25.0 Essential tremor
0.645 0.355 0.000
H35.0 Background retinopathy and retinal vascular changes
0.644 0.356 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.644 0.356 0.000
N81.0 Female urethrocele
0.643 0.357 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.643 0.357 0.000
H20 Iridocyclitis
0.642 0.358 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.641 0.359 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.641 0.359 0.000
G72 Other myopathies
0.641 0.359 0.000
D23.1 Skin of eyelid, including canthus
0.640 0.360 0.000
F42 Obsessive-compulsive disorder
0.639 0.361 0.000
F43.1 Posttraumatic stress disorder
0.639 0.361 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.639 0.361 0.000
D10.3 Other and unspecified parts of mouth
0.639 0.361 0.000
D73.0 Hyposplenism
0.639 0.361 0.000
G93 Other disorders of brain
0.638 0.362 0.000
H53-H54 Visual disturbances and blindness
0.638 0.362 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.638 0.362 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.638 0.362 0.000
C67.4 Posterior wall of bladder
0.638 0.362 0.000
F41 Other anxiety disorders
0.637 0.363 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.637 0.363 0.000
S81 Open wound of lower leg
0.636 0.364 0.000
G62 Other polyneuropathies
0.636 0.364 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.636 0.364 0.000
N36.9 Urethral disorder, unspecified
0.634 0.366 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.634 0.366 0.000
D16.2 Long bones of lower limb
0.634 0.366 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.633 0.367 0.000
F81 Specific developmental disorders of scholastic skills
0.633 0.367 0.000
O80.0 Spontaneous vertex delivery
0.632 0.368 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.631 0.369 0.000
S22.4 Multiple fractures of ribs
0.631 0.369 0.000
C18.2 Ascending colon
0.630 0.369 0.000
S32.0 Fracture of lumbar vertebra
0.630 0.370 0.000
G60 Hereditary and idiopathic neuropathy
0.629 0.371 0.000
N42.2 Atrophy of prostate
0.629 0.371 0.000
H91.2 Sudden idiopathic hearing loss
0.628 0.372 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.628 0.372 0.000
N97 Female infertility
0.628 0.372 0.000
F60.8 Other specific personality disorders
0.628 0.372 0.000
F60.7 Dependent personality disorder
0.628 0.372 0.000
F60.6 Anxious [avoidant] personality disorder
0.628 0.372 0.000
F60.5 Anankastic personality disorder
0.628 0.372 0.000
F60.4 Histrionic personality disorder
0.628 0.372 0.000
F60.2 Dissocial personality disorder
0.628 0.372 0.000
F60.1 Schizoid personality disorder
0.628 0.372 0.000
F60.0 Paranoid personality disorder
0.628 0.372 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.627 0.373 0.000
D18.1 Lymphangioma, any site
0.626 0.374 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.626 0.374 0.000
H10-H13 Disorders of conjunctiva
0.625 0.375 0.000
G96 Other disorders of central nervous system
0.624 0.376 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.623 0.376 0.000
S88 Traumatic amputation of lower leg
0.623 0.377 0.000
S87 Crushing injury of lower leg
0.623 0.377 0.000
S86 Injury of muscle and tendon at lower leg level
0.623 0.377 0.000
S85 Injury of blood vessels at lower leg level
0.623 0.377 0.000
S84 Injury of nerves at lower leg level
0.623 0.377 0.000
N10 Acute tubulo-interstitial nephritis
0.622 0.378 0.000
N81.9 Female genital prolapse, unspecified
0.622 0.378 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.622 0.378 0.000
H61 Other disorders of external ear
0.621 0.378 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.620 0.379 0.000
C83.7 Burkitt's tumour
0.620 0.379 0.000
C83.6 Undifferentiated (diffuse)
0.620 0.379 0.000
C83.5 Lymphoblastic (diffuse)
0.620 0.379 0.000
C83.4 Immunoblastic (diffuse)
0.620 0.379 0.000
C83.2 Mixed small and large cell (diffuse)
0.620 0.379 0.000
N89.5 Stricture and atresia of vagina
0.620 0.379 0.000
H35.8 Other specified retinal disorders
0.620 0.380 0.000
B35-B49 Mycoses
0.620 0.380 0.000
N32.9 Bladder disorder, unspecified
0.620 0.380 0.000
O71 Other obstetric trauma
0.620 0.380 0.000
G23 Other degenerative diseases of basal ganglia
0.620 0.380 0.000
G21 Secondary Parkinsonism
0.620 0.380 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.620 0.380 0.000
G22 Parkinsonism in diseases classified elsewhere
0.620 0.380 0.000
N36.3 Prolapsed urethral mucosa
0.619 0.381 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.619 0.381 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.619 0.381 0.000
C67.5 Bladder neck
0.619 0.381 0.000
N84.1 Polyp of cervix uteri
0.619 0.381 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.619 0.381 0.000
F32.1 Moderate depressive episode
0.619 0.381 0.000
E20-E35 Disorders of other endocrine glands
0.618 0.382 0.000
O85-O92 Complications predominantly related to the puerperium
0.618 0.382 0.000
C71 Malignant neoplasm of brain
0.617 0.383 0.000
T43.2 Other and unspecified antidepressants
0.616 0.384 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.616 0.384 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.616 0.384 0.000
T39.4 Antirheumatics, not elsewhere classified
0.616 0.384 0.000
T39.2 Pyrazolone derivatives
0.616 0.384 0.000
C18.8 Overlapping lesion of colon
0.615 0.385 0.000
C18.6 Descending colon
0.615 0.385 0.000
C18.1 Appendix
0.615 0.385 0.000
G61 Inflammatory polyneuropathy
0.615 0.385 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.615 0.385 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.615 0.385 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.615 0.385 0.000
H90.3 Sensorineural hearing loss, bilateral
0.615 0.385 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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