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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2829949
log Bayes Factor = 8.60682
Chromosome 21   position 27,222,822  (GRCh37) Explore rs2829949 on Ensembl!
Variant rs2829949 is part of Cluster X0117

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.994 0.006 0.000
C51-C58 Malignant neoplasms of female genital organs
0.988 0.012 0.000
S80-S89 Injuries to the knee and lower leg
0.983 0.017 0.000
C78.0 Secondary malignant neoplasm of lung
0.983 0.017 0.000
Chapter V Mental and behavioural disorders
0.982 0.018 0.000
N18.9 Chronic renal failure, unspecified
0.982 0.018 0.000
N18 Chronic renal failure
0.981 0.019 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.980 0.020 0.000
N17-N19 Renal failure
0.980 0.020 0.000
C53 Malignant neoplasm of cervix uteri
0.972 0.028 0.000
N17 Acute renal failure
0.966 0.034 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.964 0.036 0.000
C79 Secondary malignant neoplasm of other sites
0.964 0.036 0.000
C53.9 Cervix uteri, unspecified
0.960 0.040 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.957 0.043 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.957 0.043 0.000
C34 Malignant neoplasm of bronchus and lung
0.951 0.049 0.000
E70-E90 Metabolic disorders
0.950 0.050 0.000
S50-S59 Injuries to the elbow and forearm
0.949 0.051 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.946 0.054 0.000
S82 Fracture of lower leg, including ankle
0.944 0.056 0.000
Chapter XXI Factors influencing health status and contact with health services
0.944 0.056 0.000
N17.9 Acute renal failure, unspecified
0.942 0.058 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.938 0.062 0.000
Z51 Other medical care
0.934 0.066 0.000
Chapter I Certain infectious and parasitic diseases
0.934 0.066 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.933 0.067 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.931 0.069 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.923 0.077 0.000
F30-F39 Mood [affective] disorders
0.923 0.077 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.922 0.078 0.000
E87.5 Hyperkalaemia
0.921 0.079 0.000
C78.7 Secondary malignant neoplasm of liver
0.919 0.081 0.000
G30-G32 Other degenerative diseases of the nervous system
0.917 0.083 0.000
G54 Nerve root and plexus disorders
0.917 0.083 0.000
Z51.3 Blood transfusion without reported diagnosis
0.917 0.083 0.000
S40-S49 Injuries to the shoulder and upper arm
0.912 0.088 0.000
Z51.5 Palliative care
0.911 0.089 0.000
Z51.1 Chemotherapy session for neoplasm
0.911 0.089 0.000
L50-L54 Urticaria and erythema
0.910 0.090 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.908 0.092 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.907 0.093 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.907 0.093 0.000
N19 Unspecified renal failure
0.901 0.099 0.000
B07 Viral warts
0.898 0.102 0.000
Chapter XIV Diseases of the genitourinary system
0.896 0.104 0.000
S51 Open wound of forearm
0.895 0.105 0.000
Z51.8 Other specified medical care
0.894 0.106 0.000
C56 Malignant neoplasm of ovary
0.889 0.111 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.888 0.112 0.000
C15-C26 Malignant neoplasms of digestive organs
0.884 0.116 0.000
Chapter XX External causes of morbidity and mortality
0.882 0.118 0.000
G81 Hemiplegia
0.879 0.121 0.000
E86 Volume depletion
0.878 0.122 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.876 0.124 0.000
L53 Other erythematous conditions
0.876 0.124 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.873 0.127 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.872 0.128 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.872 0.128 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.871 0.129 0.000
N18.2 Chronic kidney disease, stage 2
0.865 0.135 0.000
S10-S19 Injuries to the neck
0.864 0.136 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.860 0.140 0.000
Chapter XXII Codes for special purposes
0.860 0.140 0.000
N17.0 Acute renal failure with tubular necrosis
0.859 0.141 0.000
D37.5 Rectum
0.857 0.143 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.857 0.143 0.000
S82.2 Fracture of shaft of tibia
0.854 0.146 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.854 0.146 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.853 0.147 0.000
L53.9 Erythematous condition, unspecified
0.852 0.148 0.000
C34.0 Main bronchus
0.850 0.150 0.000
S82.1 Fracture of upper end of tibia
0.848 0.152 0.000
F32 Depressive episode
0.847 0.153 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.847 0.153 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.845 0.155 0.000
S81 Open wound of lower leg
0.844 0.156 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.843 0.157 0.000
C34.3 Lower lobe, bronchus or lung
0.841 0.159 0.000
E87.0 Hyperosmolality and hypernatraemia
0.841 0.159 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.840 0.160 0.000
E83 Disorders of mineral metabolism
0.839 0.161 0.000
S86 Injury of muscle and tendon at lower leg level
0.835 0.165 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.834 0.166 0.000
C78.2 Secondary malignant neoplasm of pleura
0.830 0.170 0.000
C34.9 Bronchus or lung, unspecified
0.827 0.173 0.000
X60-X84 Intentional self-harm
0.826 0.174 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.825 0.175 0.000
S51.0 Open wound of elbow
0.824 0.176 0.000
G81.9 Hemiplegia, unspecified
0.818 0.182 0.000
S82.0 Fracture of patella
0.815 0.185 0.000
C32 Malignant neoplasm of larynx
0.815 0.185 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.815 0.185 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.814 0.186 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.811 0.189 0.000
E40-E46 Malnutrition
0.810 0.190 0.000
S40 Superficial injury of shoulder and upper arm
0.808 0.192 0.000
C21 Malignant neoplasm of anus and anal canal
0.808 0.192 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.806 0.194 0.000
G70-G73 Diseases of myoneural junction and muscle
0.806 0.194 0.000
G82 Paraplegia and tetraplegia
0.805 0.195 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.802 0.198 0.000
D46 Myelodysplastic syndromes
0.798 0.202 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.798 0.202 0.000
S90-S99 Injuries to the ankle and foot
0.797 0.203 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.797 0.203 0.000
Z43 Attention to artificial openings
0.794 0.206 0.000
F60-F69 Disorders of adult personality and behaviour
0.793 0.207 0.000
G62 Other polyneuropathies
0.792 0.208 0.000
S51.9 Open wound of forearm, part unspecified
0.792 0.208 0.000
S82.4 Fracture of fibula alone
0.790 0.210 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.790 0.210 0.000
C16 Malignant neoplasm of stomach
0.788 0.212 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.788 0.212 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.788 0.212 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.786 0.214 0.000
F99-F99 Unspecified mental disorder
0.786 0.214 0.000
T79-T79 Certain early complications of trauma
0.784 0.216 0.000
S89 Other and unspecified injuries of lower leg
0.783 0.217 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.782 0.218 0.000
G54.0 Brachial plexus disorders
0.782 0.218 0.000
L50 Urticaria
0.782 0.218 0.000
T00-T07 Injuries involving multiple body regions
0.781 0.219 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.781 0.219 0.000
G59.0 Diabetic mononeuropathy
0.781 0.219 0.000
Z51.9 Medical care, unspecified
0.781 0.219 0.000
Z22 Carrier of infectious disease
0.780 0.220 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.779 0.221 0.000
S82.10 Fracture of upper end of tibia (closed)
0.779 0.221 0.000
C79.6 Secondary malignant neoplasm of ovary
0.777 0.223 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.776 0.224 0.000
G83 Other paralytic syndromes
0.775 0.225 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.775 0.225 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.774 0.226 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.774 0.226 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.773 0.227 0.000
N18.3 Chronic kidney disease, stage 3
0.773 0.227 0.000
E87.6 Hypokalaemia
0.771 0.229 0.000
E83.4 Disorders of magnesium metabolism
0.768 0.232 0.000
F30 Manic episode
0.768 0.232 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.768 0.232 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.767 0.233 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.765 0.235 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.765 0.235 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.763 0.237 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.763 0.237 0.000
S42 Fracture of shoulder and upper arm
0.763 0.237 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.762 0.238 0.000
G54.8 Other nerve root and plexus disorders
0.761 0.239 0.000
B65-B83 Helminthiases
0.760 0.240 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.760 0.240 0.000
E87.7 Fluid overload
0.753 0.247 0.000
S56 Injury of muscle and tendon at forearm level
0.753 0.247 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.752 0.247 0.000
C83.0 Small cell (diffuse)
0.752 0.248 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.752 0.248 0.000
G35 Multiple sclerosis
0.751 0.249 0.000
S82.20 Fracture of shaft of tibia (closed)
0.748 0.252 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.748 0.252 0.000
Z29 Need for other prophylactic measures
0.748 0.252 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.745 0.255 0.000
C91 Lymphoid leukaemia
0.745 0.255 0.000
G60 Hereditary and idiopathic neuropathy
0.745 0.255 0.000
L10-L14 Bullous disorders
0.745 0.255 0.000
B99-B99 Other infectious diseases
0.742 0.258 0.000
S80 Superficial injury of lower leg
0.741 0.259 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.741 0.259 0.000
N00-N08 Glomerular diseases
0.740 0.260 0.000
L05 Pilonidal cyst
0.739 0.261 0.000
F70-F79 Mental retardation
0.739 0.261 0.000
D47.1 Chronic myeloproliferative disease
0.738 0.262 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.736 0.264 0.000
N18.5 Chronic kidney disease, stage 5
0.736 0.264 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.734 0.266 0.000
E50-E64 Other nutritional deficiencies
0.733 0.267 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.731 0.269 0.000
A80-A89 Viral infections of the central nervous system
0.731 0.269 0.000
C21.1 Anal canal
0.730 0.270 0.000
G62.9 Polyneuropathy, unspecified
0.729 0.271 0.000
C34.2 Middle lobe, bronchus or lung
0.729 0.271 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.728 0.272 0.000
D37.4 Colon
0.726 0.274 0.000
Z63 Other problems related to primary support group, including family circumstances
0.726 0.274 0.000
Y88 Sequelae of surgical and medical care as external cause
0.726 0.274 0.000
Z42 Follow-up care involving plastic surgery
0.726 0.274 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.725 0.275 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.725 0.275 0.000
S82.00 Fracture of patella (closed)
0.723 0.277 0.000
G83.1 Monoplegia of lower limb
0.721 0.279 0.000
G58 Other mononeuropathies
0.720 0.280 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.720 0.280 0.000
Z52 Donors of organs and tissues
0.719 0.281 0.000
T21 Burn and corrosion of trunk
0.719 0.281 0.000
F11 Mental and behavioural disorders due to use of opioids
0.718 0.282 0.000
S14 Injury of nerves and spinal cord at neck level
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
F39 Unspecified mood [affective] disorder
0.716 0.284 0.000
Y85 Sequelae of transport accidents
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.713 0.287 0.000
S52 Fracture of forearm
0.713 0.287 0.000
L40-L45 Papulosquamous disorders
0.712 0.288 0.000
Z48 Other surgical follow-up care
0.712 0.288 0.000
S40.0 Contusion of shoulder and upper arm
0.711 0.289 0.000
F32.1 Moderate depressive episode
0.710 0.289 0.000
S81.8 Open wound of other parts of lower leg
0.710 0.290 0.000
G52 Disorders of other cranial nerves
0.709 0.291 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.708 0.292 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.708 0.292 0.000
C58 Malignant neoplasm of placenta
0.708 0.292 0.000
C52 Malignant neoplasm of vagina
0.708 0.292 0.000
E20-E35 Disorders of other endocrine glands
0.708 0.292 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.708 0.292 0.000
Z22.5 Carrier of viral hepatitis
0.707 0.293 0.000
S82.21 Fracture of shaft of tibia (open)
0.706 0.294 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.705 0.295 0.000
S88 Traumatic amputation of lower leg
0.705 0.295 0.000
S87 Crushing injury of lower leg
0.705 0.295 0.000
S85 Injury of blood vessels at lower leg level
0.705 0.295 0.000
S84 Injury of nerves at lower leg level
0.705 0.295 0.000
F32.9 Depressive episode, unspecified
0.705 0.295 0.000
G37 Other demyelinating diseases of central nervous system
0.704 0.296 0.000
S31 Open wound of abdomen, lower back and pelvis
0.704 0.296 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.296 0.000
B50-B64 Protozoal diseases
0.704 0.296 0.000
E46 Unspecified protein-energy malnutrition
0.704 0.296 0.000
Z59 Problems related to housing and economic circumstances
0.704 0.296 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.703 0.297 0.000
N18.1 Chronic kidney disease, stage 1
0.703 0.297 0.000
D47.2 Monoclonal gammopathy
0.703 0.297 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.703 0.297 0.000
C31 Malignant neoplasm of accessory sinuses
0.703 0.297 0.000
C37 Malignant neoplasm of thymus
0.703 0.297 0.000
C33 Malignant neoplasm of trachea
0.703 0.297 0.000
S12 Fracture of neck
0.703 0.297 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.702 0.298 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.702 0.298 0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level
0.701 0.299 0.000
S82.7 Multiple fractures of lower leg
0.700 0.299 0.000
A65-A69 Other spirochaetal diseases
0.699 0.301 0.000
N18.8 Other chronic renal failure
0.699 0.301 0.000
F34 Persistent mood [affective] disorders
0.698 0.301 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.698 0.302 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.698 0.302 0.000
E88 Other metabolic disorders
0.698 0.302 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.697 0.303 0.000
C53.8 Overlapping lesion of cervix uteri
0.697 0.303 0.000
C53.1 Exocervix
0.697 0.303 0.000
C53.0 Endocervix
0.697 0.303 0.000
G50 Disorders of trigeminal nerve
0.697 0.303 0.000
Q28 Other congenital malformations of circulatory system
0.696 0.303 0.000
Z40 Prophylactic surgery
0.696 0.304 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.694 0.306 0.000
G80 Infantile cerebral palsy
0.694 0.306 0.000
G54.6 Phantom limb syndrome with pain
0.694 0.306 0.000
N17.8 Other acute renal failure
0.693 0.307 0.000
N17.2 Acute renal failure with medullary necrosis
0.693 0.307 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.693 0.307 0.000
G82.2 Paraplegia, unspecified
0.693 0.307 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.692 0.307 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.691 0.309 0.000
T45.0 Antiallergic and antiemetic drugs
0.691 0.309 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.691 0.309 0.000
C83.1 Small cleaved cell (diffuse)
0.690 0.310 0.000
G71 Primary disorders of muscles
0.688 0.312 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.688 0.312 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.688 0.312 0.000
S10 Superficial injury of neck
0.688 0.312 0.000
F33 Recurrent depressive disorder
0.687 0.312 0.000
F80-F89 Disorders of psychological development
0.687 0.313 0.000
S81.7 Multiple open wounds of lower leg
0.687 0.313 0.000
T17 Foreign body in respiratory tract
0.687 0.313 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.686 0.314 0.000
G20-G26 Extrapyramidal and movement disorders
0.685 0.315 0.000
T20 Burn and corrosion of head and neck
0.684 0.316 0.000
S50 Superficial injury of forearm
0.684 0.316 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.682 0.318 0.000
C34.8 Overlapping lesion of bronchus and lung
0.682 0.318 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.682 0.318 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.681 0.319 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.681 0.319 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.681 0.319 0.000
E84 Cystic fibrosis
0.681 0.319 0.000
E79 Disorders of purine and pyrimidine metabolism
0.681 0.319 0.000
E77 Disorders of glycoprotein metabolism
0.681 0.319 0.000
E76 Disorders of glycosaminoglycan metabolism
0.681 0.319 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.681 0.319 0.000
E72 Other disorders of amino-acid metabolism
0.681 0.319 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.681 0.319 0.000
E70 Disorders of aromatic amino-acid metabolism
0.681 0.319 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.681 0.319 0.000
S58 Traumatic amputation of forearm
0.680 0.319 0.000
S57 Crushing injury of forearm
0.680 0.319 0.000
S55 Injury of blood vessels at forearm level
0.680 0.319 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.680 0.319 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.680 0.320 0.000
S82.40 Fracture of fibula alone (closed)
0.680 0.320 0.000
S54 Injury of nerves at forearm level
0.680 0.320 0.000
C15 Malignant neoplasm of oesophagus
0.680 0.320 0.000
Q80-Q89 Other congenital malformations
0.679 0.321 0.000
Z51.6 Desensitisation to allergens
0.678 0.321 0.000
E87.4 Mixed disorder of acid-base balance
0.678 0.322 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.677 0.322 0.000
S82.9 Fracture of lower leg, part unspecified
0.677 0.323 0.000
V01-V09 Pedestrian injured in transport accident
0.677 0.323 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.675 0.324 0.000
L51 Erythema multiforme
0.675 0.325 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.674 0.326 0.000
L05.9 Pilonidal cyst without abscess
0.674 0.326 0.000
D37.7 Other digestive organs
0.674 0.326 0.000
Z49 Care involving dialysis
0.673 0.327 0.000
Z71.3 Dietary counselling and surveillance
0.671 0.329 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.669 0.330 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.669 0.330 0.000
A75-A79 Rickettsioses
0.669 0.330 0.000
A70-A74 Other diseases caused by chlamydiae
0.669 0.330 0.000
A20-A28 Certain zoonotic bacterial diseases
0.669 0.330 0.000
A15-A19 Tuberculosis
0.669 0.330 0.000
S59 Other and unspecified injuries of forearm
0.669 0.331 0.000
F64 Gender identity disorders
0.669 0.331 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.669 0.331 0.000
D46.2 Refractory anaemia with excess of blasts
0.668 0.332 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.668 0.332 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.668 0.332 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.668 0.332 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.668 0.332 0.000
T36 Poisoning by systemic antibiotics
0.668 0.332 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.668 0.332 0.000
C80 Malignant neoplasm without specification of site
0.667 0.333 0.000
U88 Agent resistant to multiple antibiotics
0.666 0.334 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.666 0.334 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.665 0.335 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.663 0.337 0.000
C16.6 Greater curvature of stomach, unspecified
0.662 0.338 0.000
F38 Other mood [affective] disorders
0.662 0.338 0.000
S51.7 Multiple open wounds of forearm
0.662 0.338 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.661 0.339 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.661 0.339 0.000
C95 Leukaemia of unspecified cell type
0.661 0.339 0.000
C94 Other leukaemias of specified cell type
0.661 0.339 0.000
C93 Monocytic leukaemia
0.661 0.339 0.000
C86 Other specified types of T/NK-cell lymphoma
0.661 0.339 0.000
F40 Phobic anxiety disorders
0.661 0.339 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.660 0.339 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.660 0.340 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.660 0.340 0.000
V20-V29 Motorcycle rider injured in transport accident
0.660 0.340 0.000
D45 Polycythaemia vera
0.659 0.340 0.000
E10-E14 Diabetes mellitus
0.659 0.341 0.000
E55 Vitamin D deficiency
0.658 0.342 0.000
S82.3 Fracture of lower end of tibia
0.658 0.342 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.657 0.342 0.000
G54.7 Phantom limb syndrome without pain
0.657 0.342 0.000
G54.5 Neuralgic amyotrophy
0.657 0.342 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.657 0.342 0.000
G54.3 Thoracic root disorders, not elsewhere classified
0.657 0.342 0.000
G54.2 Cervical root disorders, not elsewhere classified
0.657 0.342 0.000
G54.1 Lumbosacral plexus disorders
0.657 0.342 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.657 0.343 0.000
E83.3 Disorders of phosphorus metabolism
0.657 0.343 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.656 0.344 0.000
G82.5 Tetraplegia, unspecified
0.655 0.345 0.000
L50.8 Other urticaria
0.655 0.345 0.000
F43 Reaction to severe stress, and adjustment disorders
0.655 0.345 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.654 0.346 0.000
G63.2 Diabetic polyneuropathy
0.654 0.346 0.000
S48 Traumatic amputation of shoulder and upper arm
0.654 0.346 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.654 0.346 0.000
S44 Injury of nerves at shoulder and upper arm level
0.654 0.346 0.000
S47 Crushing injury of shoulder and upper arm
0.654 0.346 0.000
S20-S29 Injuries to the thorax
0.653 0.347 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.653 0.347 0.000
L43 Lichen planus
0.653 0.347 0.000
L54 Erythema in diseases classified elsewhere
0.653 0.347 0.000
L52 Erythema nodosum
0.653 0.347 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.653 0.347 0.000
E73 Lactose intolerance
0.653 0.347 0.000
F48 Other neurotic disorders
0.653 0.347 0.000
Z74 Problems related to care-provider dependency
0.652 0.348 0.000
G81.1 Spastic hemiplegia
0.652 0.348 0.000
G64 Other disorders of peripheral nervous system
0.651 0.349 0.000
A00-A09 Intestinal infectious diseases
0.651 0.349 0.000
F32.8 Other depressive episodes
0.651 0.349 0.000
D37.9 Digestive organ, unspecified
0.650 0.349 0.000
D37.3 Appendix
0.650 0.349 0.000
B06 Rubella [German measles]
0.650 0.350 0.000
B05 Measles
0.650 0.350 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.650 0.350 0.000
B04 Monkeypox
0.650 0.350 0.000
B03 Smallpox
0.650 0.350 0.000
Y00-Y09 Assault
0.650 0.350 0.000
T43.2 Other and unspecified antidepressants
0.650 0.350 0.000
S82.6 Fracture of lateral malleolus
0.650 0.350 0.000
S42.4 Fracture of lower end of humerus
0.650 0.350 0.000
C18 Malignant neoplasm of colon
0.649 0.351 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.649 0.351 0.000
S36 Injury of intra-abdominal organs
0.648 0.352 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.648 0.352 0.000
C21.0 Anus, unspecified
0.647 0.353 0.000
Z75 Problems related to medical facilities and other health care
0.646 0.354 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.646 0.354 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.646 0.354 0.000
D37.1 Stomach
0.646 0.354 0.000
F99 Mental disorder, not otherwise specified
0.645 0.355 0.000
B01 Varicella [chickenpox]
0.645 0.355 0.000
Z63.5 Disruption of family by separation and divorce
0.645 0.355 0.000
Q40 Other congenital malformations of upper alimentary tract
0.644 0.356 0.000
X50-X57 Overexertion, travel and privation
0.644 0.356 0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level
0.644 0.356 0.000
Z29.0 Isolation
0.643 0.357 0.000
F30.0 Hypomania
0.643 0.357 0.000
Chapter VIII Diseases of the ear and mastoid process
0.643 0.357 0.000
E28 Ovarian dysfunction
0.643 0.357 0.000
C32.0 Glottis
0.642 0.358 0.000
Z29.8 Other specified prophylactic measures
0.642 0.358 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.642 0.358 0.000
Z43.8 Attention to other artificial openings
0.641 0.359 0.000
T66-T78 Other and unspecified effects of external causes
0.641 0.359 0.000
S89.9 Unspecified injury of lower leg
0.641 0.359 0.000
D37.0 Lip, oral cavity and pharynx
0.641 0.359 0.000
D44.4 Craniopharyngeal duct
0.640 0.360 0.000
S00-S09 Injuries to the head
0.639 0.361 0.000
T14 Injury of unspecified body region
0.639 0.361 0.000
D37.6 Liver, gallbladder and bile ducts
0.638 0.362 0.000
F42 Obsessive-compulsive disorder
0.638 0.362 0.000
G31.2 Degeneration of nervous system due to alcohol
0.638 0.362 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.637 0.363 0.000
B15-B19 Viral hepatitis
0.636 0.364 0.000
B80 Enterobiasis
0.636 0.364 0.000
C83.3 Large cell (diffuse)
0.635 0.365 0.000
S91 Open wound of ankle and foot
0.634 0.366 0.000
C23 Malignant neoplasm of gallbladder
0.633 0.366 0.000
Z40.8 Other prophylactic surgery
0.633 0.367 0.000
Z63.7 Other stressful life events affecting family and household
0.633 0.367 0.000
Y35-Y36 Legal intervention and operations of war
0.632 0.368 0.000
Y10-Y34 Event of undetermined intent
0.632 0.368 0.000
X85-X99 Assault
0.632 0.368 0.000
X30-X39 Exposure to forces of nature
0.632 0.368 0.000
X10-X19 Contact with heat and hot substances
0.632 0.368 0.000
X00-X09 Exposure to smoke, fire and flames
0.632 0.368 0.000
W75-W84 Other accidental threats to breathing
0.632 0.368 0.000
W65-W74 Accidental drowning and submersion
0.632 0.368 0.000
V98-V99 Other and unspecified transport accidents
0.632 0.368 0.000
V95-V97 Air and space transport accidents
0.632 0.368 0.000
V90-V94 Water transport accidents
0.632 0.368 0.000
V70-V79 Bus occupant injured in transport accident
0.632 0.368 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.632 0.368 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.632 0.368 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.632 0.368 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.631 0.369 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.631 0.369 0.000
T45.5 Anticoagulants
0.631 0.369 0.000
G81.0 Flaccid hemiplegia
0.630 0.370 0.000
W50-W64 Exposure to animate mechanical forces
0.630 0.370 0.000
C51 Malignant neoplasm of vulva
0.630 0.370 0.000
F11.2 Dependence syndrome
0.629 0.371 0.000
V80-V89 Other land transport accidents
0.629 0.371 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.629 0.371 0.000
C32.1 Supraglottis
0.629 0.371 0.000
G36 Other acute disseminated demyelination
0.628 0.372 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.628 0.372 0.000
C81 Hodgkin's disease
0.628 0.372 0.000
C09 Malignant neoplasm of tonsil
0.628 0.372 0.000
L53.3 Other chronic figurate erythema
0.628 0.372 0.000
L53.2 Erythema marginatum
0.628 0.372 0.000
L53.1 Erythema annulare centrifugum
0.628 0.372 0.000
L53.0 Toxic erythema
0.628 0.372 0.000
L05.0 Pilonidal cyst with abscess
0.628 0.372 0.000
Z22.8 Carrier of other infectious diseases
0.627 0.373 0.000
T43.6 Psychostimulants with abuse potential
0.627 0.373 0.000
C82.0 Small cleaved cell, follicular
0.627 0.373 0.000
F11.1 Harmful use
0.626 0.374 0.000
T25 Burn and corrosion of ankle and foot
0.626 0.374 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.625 0.374 0.000
C83.7 Burkitt's tumour
0.625 0.374 0.000
C83.6 Undifferentiated (diffuse)
0.625 0.374 0.000
C83.5 Lymphoblastic (diffuse)
0.625 0.374 0.000
C83.4 Immunoblastic (diffuse)
0.625 0.374 0.000
C83.2 Mixed small and large cell (diffuse)
0.625 0.374 0.000
Z28 Immunisation not carried out
0.625 0.375 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.625 0.375 0.000
Z26 Need for immunisation against other single infectious diseases
0.625 0.375 0.000
Z25 Need for immunisation against other single viral diseases
0.625 0.375 0.000
Z24 Need for immunisation against certain single viral diseases
0.625 0.375 0.000
Z23 Need for immunisation against single bacterial diseases
0.625 0.375 0.000
Z20 Contact with and exposure to communicable diseases
0.625 0.375 0.000
T23 Burn and corrosion of wrist and hand
0.624 0.376 0.000
E74 Other disorders of carbohydrate metabolism
0.624 0.376 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.623 0.377 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.623 0.377 0.000
C16.9 Stomach, unspecified
0.622 0.378 0.000
X20-X29 Contact with venomous animals and plants
0.621 0.379 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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