TreeWAS – Variant ID: rs28373246

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M45-M49 Spondylopathies	1.000	0.000	0.000
M20-M25 Other joint disorders	0.998	0.002	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.995	0.005	0.000
M25 Other joint disorders, not elsewhere classified	0.985	0.015	0.000
M65-M68 Disorders of synovium and tendon	0.962	0.038	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.956	0.044	0.000
M70-M79 Other soft tissue disorders	0.951	0.049	0.000
M25.5 Pain in joint	0.945	0.055	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.940	0.060	0.000
H20 Iridocyclitis	0.939	0.061	0.000
Chapter VII Diseases of the eye and adnexa	0.939	0.061	0.000
M65 Synovitis and tenosynovitis	0.935	0.065	0.000
H20.9 Iridocyclitis, unspecified	0.934	0.066	0.000
H30-H36 Disorders of choroid and retina	0.932	0.068	0.000
H40-H42 Glaucoma	0.925	0.075	0.000
H40 Glaucoma	0.915	0.085	0.000
M24 Other specific joint derangements	0.914	0.086	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.913	0.087	0.000
H33 Retinal detachments and breaks	0.906	0.094	0.000
H40.9 Glaucoma, unspecified	0.905	0.095	0.000
M22 Disorders of patella	0.904	0.096	0.000
K90.0 Coeliac disease	0.000	0.108	0.892
H33.0 Retinal detachment with retinal break	0.888	0.112	0.000
M34 Systemic sclerosis	0.887	0.113	0.000
M25.4 Effusion of joint	0.880	0.120	0.000
M21 Other acquired deformities of limbs	0.878	0.122	0.000
M86-M90 Other osteopathies	0.878	0.122	0.000
H35 Other retinal disorders	0.876	0.124	0.000
M00-M03 Infectious arthropathies	0.859	0.141	0.000
M25.56 Pain in joint (Lower leg)	0.855	0.145	0.000
M46 Other inflammatory spondylopathies	0.852	0.148	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.850	0.150	0.000
M91-M94 Chondropathies	0.848	0.152	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.845	0.155	0.000
M24.1 Other articular cartilage disorders	0.844	0.156	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.837	0.163	0.000
M25.50 Pain in joint (Multiple sites)	0.834	0.166	0.000
H20.0 Acute and subacute iridocyclitis	0.832	0.168	0.000
M25.8 Other specified joint disorders	0.832	0.168	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.830	0.170	0.000
M60-M63 Disorders of muscles	0.825	0.175	0.000
M77 Other enthesopathies	0.823	0.177	0.000
M71 Other bursopathies	0.820	0.180	0.000
M25.52 Pain in joint (Upper arm)	0.810	0.190	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.806	0.194	0.000
M25.59 Pain in joint (Site unspecified)	0.799	0.201	0.000
M35 Other systemic involvement of connective tissue	0.792	0.208	0.000
M22.8 Other disorders of patella	0.786	0.214	0.000
M75 Shoulder lesions	0.785	0.215	0.000
M49 Spondylopathies in diseases classified elsewhere	0.784	0.216	0.000
H20.1 Chronic iridocyclitis	0.782	0.218	0.000
H40.0 Glaucoma suspect	0.779	0.221	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.775	0.225	0.000
H35.5 Hereditary retinal dystrophy	0.775	0.225	0.000
H33.3 Retinal breaks without detachment	0.774	0.226	0.000
M25.51 Pain in joint (Shoulder region)	0.773	0.227	0.000
M25.9 Joint disorder, unspecified	0.772	0.228	0.000
M80-M85 Disorders of bone density and structure	0.770	0.230	0.000
M89 Other disorders of bone	0.766	0.234	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.762	0.238	0.000
H10-H13 Disorders of conjunctiva	0.759	0.241	0.000
M22.4 Chondromalacia patellae	0.756	0.244	0.000
M34.9 Systemic sclerosis, unspecified	0.755	0.244	0.000
M25.46 Effusion of joint (Lower leg)	0.754	0.246	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.746	0.254	0.000
M02 Reactive arthropathies	0.742	0.258	0.000
M77.9 Enthesopathy, unspecified	0.738	0.262	0.000
M65.8 Other synovitis and tenosynovitis	0.737	0.263	0.000
M24.0 Loose body in joint	0.729	0.271	0.000
H40.1 Primary open-angle glaucoma	0.728	0.272	0.000
H01 Other inflammation of eyelid	0.728	0.272	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.727	0.273	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.725	0.275	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.719	0.281	0.000
H35.4 Peripheral retinal degeneration	0.718	0.282	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
M66 Spontaneous rupture of synovium and tendon	0.717	0.283	0.000
H00 Hordeolum and chalazion	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285	0.000
M33 Dermatopolymyositis	0.715	0.285	0.000
M32 Systemic lupus erythematosus	0.715	0.285	0.000
M30 Polyarteritis nodosa and related conditions	0.715	0.285	0.000
H16 Keratitis	0.713	0.287	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.711	0.289	0.000
M79.6 Pain in limb	0.710	0.290	0.000
M25.2 Flail joint	0.706	0.294	0.000
M25.1 Fistula of joint	0.706	0.294	0.000
H35.8 Other specified retinal disorders	0.705	0.295	0.000
M94 Other disorders of cartilage	0.703	0.296	0.000
M34.8 Other forms of systemic sclerosis	0.702	0.298	0.000
M62 Other disorders of muscle	0.700	0.300	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.699	0.301	0.000
H18 Other disorders of cornea	0.698	0.302	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.697	0.303	0.000
H36 Retinal disorders in diseases classified elsewhere	0.693	0.307	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.689	0.310	0.000
M25.0 Haemarthrosis	0.688	0.312	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.688	0.312	0.000
M21.3 Wrist or foot drop (acquired)	0.687	0.313	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.686	0.314	0.000
M89.9 Disorder of bone, unspecified	0.686	0.314	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.685	0.315	0.000
M88 Paget's disease of bone [osteitis deformans]	0.684	0.316	0.000
M76 Enthesopathies of lower limb, excluding foot	0.682	0.318	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.682	0.318	0.000
H21 Other disorders of iris and ciliary body	0.682	0.318	0.000
M34.1 CR(E)ST syndrome	0.681	0.319	0.000
H43-H45 Disorders of vitreous body and globe	0.680	0.320	0.000
M05-M14 Inflammatory polyarthropathies	0.680	0.320	0.000
M25.3 Other instability of joint	0.679	0.320	0.000
M48 Other spondylopathies	0.679	0.321	0.000
M25.58 Pain in joint (Other)	0.677	0.323	0.000
H35.9 Retinal disorder, unspecified	0.677	0.323	0.000
H25-H28 Disorders of lens	0.674	0.326	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.674	0.326	0.000
H17 Corneal scars and opacities	0.674	0.326	0.000
H15 Disorders of sclera	0.674	0.326	0.000
H20.8 Other iridocyclitis	0.673	0.326	0.000
H20.2 Lens-induced iridocyclitis	0.673	0.326	0.000
H35.2 Other proliferative retinopathy	0.673	0.327	0.000
H05 Disorders of orbit	0.672	0.328	0.000
M25.86 Other specified joint disorders (Lower leg)	0.671	0.329	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.670	0.330	0.000
M65.2 Calcific tendinitis	0.670	0.330	0.000
M65.1 Other infective (teno)synovitis	0.670	0.330	0.000
M65.0 Abscess of tendon sheath	0.670	0.330	0.000
M79.62 Pain in limb (Upper arm)	0.669	0.331	0.000
H35.0 Background retinopathy and retinal vascular changes	0.669	0.331	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.668	0.332	0.000
H31 Other disorders of choroid	0.668	0.332	0.000
H30 Chorioretinal inflammation	0.668	0.332	0.000
M21.1 Varus deformity, not elsewhere classified	0.668	0.332	0.000
M84 Disorders of continuity of bone	0.667	0.333	0.000
M21.4 Flat foot [pes planus] (acquired)	0.667	0.333	0.000
M25.54 Pain in joint (Hand)	0.666	0.333	0.000
H42 Glaucoma in diseases classified elsewhere	0.663	0.337	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.662	0.338	0.000
M50-M54 Other dorsopathies	0.662	0.338	0.000
M21.2 Flexion deformity	0.661	0.339	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.661	0.339	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.660	0.340	0.000
M86 Osteomyelitis	0.659	0.340	0.000
M75.3 Calcific tendinitis of shoulder	0.659	0.341	0.000
M67 Other disorders of synovium and tendon	0.659	0.341	0.000
M92 Other juvenile osteochondrosis	0.657	0.343	0.000
M75.5 Bursitis of shoulder	0.657	0.343	0.000
H40.8 Other glaucoma	0.656	0.344	0.000
H40.6 Glaucoma secondary to drugs	0.656	0.344	0.000
H40.4 Glaucoma secondary to eye inflammation	0.656	0.344	0.000
H40.3 Glaucoma secondary to eye trauma	0.656	0.344	0.000
M24.9 Joint derangement, unspecified	0.655	0.345	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.655	0.345	0.000
M24.7 Protrusio acetabuli	0.655	0.345	0.000
M24.6 Ankylosis of joint	0.655	0.345	0.000
M24.5 Contracture of joint	0.655	0.345	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.655	0.345	0.000
M24.2 Disorder of ligament	0.655	0.345	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.655	0.345	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.655	0.345	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.655	0.345	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.655	0.345	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.655	0.345	0.000
M22.2 Patellofemoral disorders	0.653	0.346	0.000
H34 Retinal vascular occlusions	0.653	0.347	0.000
M75.1 Rotator cuff syndrome	0.652	0.348	0.000
M00 Pyogenic arthritis	0.650	0.350	0.000
M95.0 Acquired deformity of nose	0.650	0.350	0.000
M25.47 Effusion of joint (Ankle and foot)	0.650	0.350	0.000
H33.4 Traction detachment of retina	0.650	0.350	0.000
H33.1 Retinoschisis and retinal cysts	0.650	0.350	0.000
M21.0 Valgus deformity, not elsewhere classified	0.650	0.350	0.000
H10 Conjunctivitis	0.650	0.350	0.000
M22.1 Recurrent subluxation of patella	0.648	0.352	0.000
M22.9 Disorder of patella, unspecified	0.648	0.352	0.000
M22.3 Other derangements of patella	0.648	0.352	0.000
M22.0 Recurrent dislocation of patella	0.648	0.352	0.000
H01.0 Blepharitis	0.645	0.355	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.644	0.356	0.000
M79.2 Neuralgia and neuritis, unspecified	0.642	0.358	0.000
M25.7 Osteophyte	0.637	0.363	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.636	0.364	0.000
M34.0 Progressive systemic sclerosis	0.636	0.364	0.000
M90 Osteopathies in diseases classified elsewhere	0.636	0.364	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.635	0.365	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.635	0.365	0.000
H02 Other disorders of eyelid	0.631	0.369	0.000
M25.49 Effusion of joint (Site unspecified)	0.631	0.369	0.000
M25.48 Effusion of joint (Other)	0.631	0.369	0.000
M25.44 Effusion of joint (Hand)	0.631	0.369	0.000
M25.43 Effusion of joint (Forearm)	0.631	0.369	0.000
M25.42 Effusion of joint (Upper arm)	0.631	0.369	0.000
M25.41 Effusion of joint (Shoulder region)	0.631	0.369	0.000
M25.40 Effusion of joint (Multiple sites)	0.631	0.369	0.000
M21.9 Acquired deformity of limb, unspecified	0.630	0.370	0.000
M21.8 Other specified acquired deformities of limbs	0.630	0.370	0.000
M21.7 Unequal limb length (acquired)	0.630	0.370	0.000
M21.6 Other acquired deformities of ankle and foot	0.630	0.370	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.629	0.371	0.000
H35.7 Separation of retinal layers	0.628	0.372	0.000
H35.1 Retinopathy of prematurity	0.628	0.372	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.625	0.375	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.621	0.379	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.620	0.380	0.000
M93 Other osteochondropathies	0.620	0.380	0.000
M40-M43 Deforming dorsopathies	0.618	0.381	0.000
M79.1 Myalgia	0.617	0.383	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.616	0.384	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.616	0.384	0.000
M65.3 Trigger finger	0.615	0.385	0.000
M02.3 Reiter's disease	0.614	0.385	0.000
M62.8 Other specified disorders of muscle	0.611	0.389	0.000
M75.2 Bicipital tendinitis	0.611	0.389	0.000
M46.8 Other specified inflammatory spondylopathies	0.611	0.389	0.000
M46.5 Other infective spondylopathies	0.611	0.389	0.000
M46.4 Discitis, unspecified	0.611	0.389	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.611	0.389	0.000
M46.2 Osteomyelitis of vertebra	0.611	0.389	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.611	0.389	0.000
M46.0 Spinal enthesopathy	0.611	0.389	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.608	0.392	0.000
H00.1 Chalazion	0.606	0.394	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.606	0.394	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.605	0.394	0.000
M24.18 Other articular cartilage disorders (Other)	0.605	0.394	0.000
M24.14 Other articular cartilage disorders (Hand)	0.605	0.394	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.605	0.394	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.605	0.394	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.605	0.394	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.605	0.394	0.000
M02.9 Reactive arthopathy, unspecified	0.604	0.396	0.000
M35.7 Hypermobility syndrome	0.602	0.398	0.000
M79.7 Fibromyalgia	0.602	0.398	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.602	0.398	0.000
M35.3 Polymyalgia rheumatica	0.601	0.399	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.601	0.399	0.000
H33.5 Other retinal detachments	0.600	0.399	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.599	0.400	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.599	0.401	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.598	0.402	0.000
H25 Senile cataract	0.598	0.402	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.596	0.403	0.000
M25.88 Other specified joint disorders (Other)	0.596	0.403	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.596	0.403	0.000
M25.83 Other specified joint disorders (Forearm)	0.596	0.403	0.000
M25.82 Other specified joint disorders (Upper arm)	0.596	0.403	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.596	0.403	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.596	0.403	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.596	0.404	0.000
M99 Biomechanical lesions, not elsewhere classified	0.595	0.405	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.592	0.408	0.000
M61 Calcification and ossification of muscle	0.592	0.408	0.000
M60 Myositis	0.592	0.408	0.000
M77.1 Lateral epicondylitis	0.591	0.409	0.000
H40.2 Primary angle-closure glaucoma	0.591	0.409	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.590	0.409	0.000
M77.5 Other enthesopathy of foot	0.590	0.409	0.000
M77.3 Calcaneal spur	0.590	0.409	0.000
M77.2 Periarthritis of wrist	0.590	0.409	0.000
M77.0 Medial epicondylitis	0.590	0.409	0.000
M24.07 Loose body in joint (Ankle and foot)	0.590	0.410	0.000
M71.9 Bursopathy, unspecified	0.588	0.412	0.000
M71.8 Other specified bursopathies	0.588	0.412	0.000
M71.5 Other bursitis, not elsewhere classified	0.588	0.412	0.000
M71.4 Calcium deposit in bursa	0.588	0.412	0.000
M71.3 Other bursal cyst	0.588	0.412	0.000
M71.1 Other infective bursitis	0.588	0.412	0.000
M71.0 Abscess of bursa	0.588	0.412	0.000
M87 Osteonecrosis	0.587	0.412	0.000
M35.0 Sicca syndrome [Sjogren]	0.587	0.413	0.000
M07 Psoriatic and enteropathic arthropathies	0.583	0.417	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.582	0.418	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.582	0.418	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.579	0.421	0.000
M79.9 Soft tissue disorder, unspecified	0.578	0.422	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.578	0.422	0.000
M79.3 Panniculitis, unspecified	0.578	0.422	0.000
M77.4 Metatarsalgia	0.574	0.426	0.000
M25.84 Other specified joint disorders (Hand)	0.571	0.429	0.000
M94.2 Chondromalacia	0.569	0.431	0.000
M85 Other disorders of bone density and structure	0.568	0.431	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.568	0.432	0.000
M35.8 Other specified systemic involvement of connective tissue	0.568	0.432	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.568	0.432	0.000
M35.5 Multifocal fibrosclerosis	0.568	0.432	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.568	0.432	0.000
M35.2 Behcet's disease	0.568	0.432	0.000
M35.1 Other overlap syndromes	0.568	0.432	0.000
H40.5 Glaucoma secondary to other eye disorders	0.563	0.437	0.000
M75.8 Other shoulder lesions	0.562	0.437	0.000
H35.6 Retinal haemorrhage	0.562	0.438	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.562	0.438	0.000
M49.4 Neuropathic spondylopathy	0.562	0.438	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.562	0.438	0.000
M49.2 Enterobacterial spondylitis	0.562	0.438	0.000
M49.1 Brucella spondylitis	0.562	0.438	0.000
M49.0 Tuberculosis of spine	0.562	0.438	0.000
H25.0 Senile incipient cataract	0.562	0.438	0.000
M80 Osteoporosis with pathological fracture	0.561	0.439	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.557	0.443	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.555	0.444	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.554	0.446	0.000
M25.98 Joint disorder, unspecified (Other)	0.554	0.446	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.554	0.446	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.554	0.446	0.000
M25.94 Joint disorder, unspecified (Hand)	0.554	0.446	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.554	0.446	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.554	0.446	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.554	0.446	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.554	0.446	0.000
H35.3 Degeneration of macula and posterior pole	0.553	0.447	0.000
M83 Adult osteomalacia	0.552	0.448	0.000
M82 Osteoporosis in diseases classified elsewhere	0.552	0.448	0.000
M94.8 Other specified disorders of cartilage	0.550	0.450	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.550	0.450	0.000
H16.0 Corneal ulcer	0.550	0.450	0.000
M89.8 Other specified disorders of bone	0.549	0.451	0.000
M89.6 Osteopathy after poliomyelitis	0.549	0.451	0.000
M89.5 Osteolysis	0.549	0.451	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.549	0.451	0.000
M89.3 Hypertrophy of bone	0.549	0.451	0.000
M89.2 Other disorders of bone development and growth	0.549	0.451	0.000
M89.1 Epiphyseal arrest	0.549	0.451	0.000
M89.0 Algoneurodystrophy	0.549	0.451	0.000
M79.69 Pain in limb (Site unspecified)	0.549	0.451	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.549	0.451	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.549	0.451	0.000
H02.0 Entropion and trichiasis of eyelid	0.548	0.452	0.000
M25.53 Pain in joint (Forearm)	0.548	0.452	0.000
K90 Intestinal malabsorption	0.000	0.453	0.547
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.547	0.453	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.547	0.453	0.000
H05.2 Exophthalmic conditions	0.546	0.454	0.000
M88.9 Paget's disease of bone, unspecified	0.545	0.455	0.000
M79.5 Residual foreign body in soft tissue	0.544	0.455	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.544	0.456	0.000
M66.0 Rupture of popliteal cyst	0.541	0.459	0.000
H18.2 Other corneal oedema	0.540	0.460	0.000
M51 Other intervertebral disk disorders	0.540	0.460	0.000
H55-H59 Other disorders of eye and adnexa	0.536	0.463	0.000
H43 Disorders of vitreous body	0.535	0.465	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.535	0.465	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.535	0.465	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.535	0.465	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.535	0.465	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.535	0.465	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.535	0.465	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.535	0.465	0.000
M79.61 Pain in limb (Shoulder region)	0.534	0.466	0.000
M24.02 Loose body in joint (Upper arm)	0.532	0.468	0.000
M02.8 Other reactive arthropathies	0.532	0.468	0.000
M02.2 Postimmunisation arthropathy	0.532	0.468	0.000
M02.1 Postdysenteric arthropathy	0.532	0.468	0.000
M02.0 Arthropathy following intestinal bypass	0.532	0.468	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.531	0.469	0.000
H10.9 Conjunctivitis, unspecified	0.530	0.470	0.000
H10.4 Chronic conjunctivitis	0.529	0.471	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.529	0.471	0.000
M77.98 Enthesopathy, unspecified (Other)	0.529	0.471	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.529	0.471	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.529	0.471	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.529	0.471	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.529	0.471	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.529	0.471	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.529	0.471	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.529	0.471	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.529	0.471	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.529	0.471	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.529	0.471	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.529	0.471	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.529	0.471	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.529	0.471	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.529	0.471	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.529	0.471	0.000
H18.4 Corneal degeneration	0.527	0.473	0.000
M25.71 Osteophyte (Shoulder region)	0.526	0.474	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.524	0.476	0.000
H50 Other strabismus	0.524	0.476	0.000
M75.9 Shoulder lesion, unspecified	0.523	0.477	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.523	0.477	0.000
M02.39 Reiter's disease (Site unspecified)	0.523	0.477	0.000
M79.60 Pain in limb (Multiple sites)	0.523	0.477	0.000
M24.09 Loose body in joint (Site unspecified)	0.523	0.477	0.000
M24.08 Loose body in joint (Other)	0.523	0.477	0.000
M24.06 Loose body in joint-Lower leg	0.523	0.477	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.523	0.477	0.000
M24.04 Loose body in joint (Hand)	0.523	0.477	0.000
M24.03 Loose body in joint (Forearm)	0.523	0.477	0.000
M24.01 Loose body in joint (Shoulder region)	0.523	0.477	0.000
M24.00 Loose body in joint (Multiple sites)	0.523	0.477	0.000
M79.0 Rheumatism, unspecified	0.523	0.477	0.000
H01.9 Inflammation of eyelid, unspecified	0.522	0.478	0.000
H01.8 Other specified inflammation of eyelid	0.522	0.478	0.000
H01.1 Non-infectious dermatoses of eyelid	0.522	0.478	0.000
H36.0 Diabetic retinopathy	0.522	0.478	0.000
M72 Fibroblastic disorders	0.521	0.478	0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.521	0.479	0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.521	0.479	0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.521	0.479	0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.521	0.479	0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.521	0.479	0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.521	0.479	0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.521	0.479	0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.521	0.479	0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.521	0.479	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.521	0.479	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.520	0.480	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.520	0.480	0.000
M95.5 Acquired deformity of pelvis	0.520	0.480	0.000
M95.4 Acquired deformity of chest and rib	0.520	0.480	0.000
M95.3 Acquired deformity of neck	0.520	0.480	0.000
M95.2 Other acquired deformity of head	0.520	0.480	0.000
M95.1 Cauliflower ear	0.520	0.480	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.518	0.482	0.000
M25.57 Pain in joint (Ankle and foot)	0.517	0.483	0.000
H34.8 Other retinal vascular occlusions	0.516	0.483	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.515	0.485	0.000
M79.67 Pain in limb (Ankle and foot)	0.515	0.485	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.514	0.486	0.000
M66.4 Spontaneous rupture of other tendons	0.514	0.486	0.000
M66.3 Spontaneous rupture of flexor tendons	0.514	0.486	0.000
M66.2 Spontaneous rupture of extensor tendons	0.514	0.486	0.000
M66.1 Rupture of synovium	0.514	0.486	0.000
M07.3 Other psoriatic arthropathies	0.514	0.486	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.513	0.487	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.513	0.487	0.000
M30.2 Juvenile polyarteritis	0.513	0.487	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.513	0.487	0.000
M30.0 Polyarteritis nodosa	0.513	0.487	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.513	0.487	0.000
M32.8 Other forms of systemic lupus erythematosus	0.513	0.487	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.513	0.487	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.513	0.487	0.000
M33.9 Dermatopolymyositis, unspecified	0.513	0.487	0.000
M33.2 Polymyositis	0.513	0.487	0.000
M33.1 Other dermatomyositis	0.513	0.487	0.000
M33.0 Juvenile dermatomyositis	0.513	0.487	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.513	0.487	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.513	0.487	0.000
M36.3 Arthropathy in other blood disorders	0.513	0.487	0.000
M36.2 Haemophilic arthropathy	0.513	0.487	0.000
M36.1 Arthropathy in neoplastic disease	0.513	0.487	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.513	0.487	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.512	0.488	0.000
H16.9 Keratitis, unspecified	0.511	0.489	0.000
H16.8 Other keratitis	0.511	0.489	0.000
H16.4 Corneal neovascularisation	0.511	0.489	0.000
H16.3 Interstitial and deep keratitis	0.511	0.489	0.000
H16.2 Keratoconjunctivitis	0.511	0.489	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.511	0.489	0.000
M79.68 Pain in limb (Other)	0.509	0.491	0.000
H25.1 Senile nuclear cataract	0.509	0.491	0.000
H18.8 Other specified disorders of cornea	0.507	0.493	0.000
H18.6 Keratoconus	0.507	0.493	0.000
M25.19 Fistula of joint (Site unspecified)	0.506	0.494	0.000
M25.18 Fistula of joint (Other)	0.506	0.494	0.000
M25.17 Fistula of joint (Ankle and foot)	0.506	0.494	0.000
M25.16 Fistula of joint (Lower leg)	0.506	0.494	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.506	0.494	0.000
M25.14 Fistula of joint (Hand)	0.506	0.494	0.000
M25.13 Fistula of joint (Forearm)	0.506	0.494	0.000
M25.12 Fistula of joint (Upper arm)	0.506	0.494	0.000
M25.11 Fistula of joint (Shoulder region)	0.506	0.494	0.000
M25.10 Fistula of joint (Multiple sites)	0.506	0.494	0.000
M25.29 Flail joint (Site unspecified)	0.506	0.494	0.000
M25.28 Flail joint (Other)	0.506	0.494	0.000
M25.27 Flail joint (Ankle and foot)	0.506	0.494	0.000
M25.26 Flail joint (Lower leg)	0.506	0.494	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.506	0.494	0.000
M25.24 Flail joint (Hand)	0.506	0.494	0.000
M25.23 Flail joint (Forearm)	0.506	0.494	0.000
M25.22 Flail joint (Upper arm)	0.506	0.494	0.000
M25.21 Flail joint (Shoulder region)	0.506	0.494	0.000
M25.20 Flail joint (Multiple sites)	0.506	0.494	0.000
H11 Other disorders of conjunctiva	0.506	0.494	0.000
H02.8 Other specified disorders of eyelid	0.506	0.494	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.505	0.494	0.000
M21.24 Flexion deformity (Hand)	0.505	0.494	0.000
M02.90 Reactive arthropathy, unspecified (Multiple sites)	0.505	0.495	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.504	0.495	0.000
M94.9 Disorder of cartilage, unspecified	0.504	0.495	0.000
M94.3 Chondrolysis	0.504	0.495	0.000
M94.1 Relapsing polychondritis	0.504	0.495	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.504	0.495	0.000
M23 Internal derangement of knee	0.504	0.496	0.000
M86.9 Osteomyelitis, unspecified	0.503	0.497	0.000
M62.9 Disorder of muscle, unspecified	0.502	0.498	0.000
M62.6 Muscle strain	0.502	0.498	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.502	0.498	0.000
M62.4 Contracture of muscle	0.502	0.498	0.000
M62.3 Immobility syndrome (paraplegic)	0.502	0.498	0.000
M62.2 Ischaemic infarction of muscle	0.502	0.498	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations