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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28383249
log Bayes Factor = 100.141
Chromosome 6   position 32,585,500  (GRCh37) Explore rs28383249 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M20-M25 Other joint disorders
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
M35.0 Sicca syndrome [Sjogren]
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
E10.1 With ketoacidosis
0.000 0.002 0.998
J33.9 Nasal polyp, unspecified
0.000 0.002 0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.003 0.997
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.003 0.997
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.003 0.997
G35 Multiple sclerosis
0.000 0.006 0.994
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.009 0.991
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.012 0.988
M34 Systemic sclerosis
0.000 0.012 0.988
H02 Other disorders of eyelid
0.000 0.012 0.988
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.014 0.986
L20-L30 Dermatitis and eczema
0.000 0.019 0.981
J20-J22 Other acute lower respiratory infections
0.000 0.022 0.978
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.025 0.975
J44 Other chronic obstructive pulmonary disease
0.000 0.025 0.975
E20-E35 Disorders of other endocrine glands
0.000 0.025 0.975
H04 Disorders of lachrymal system
0.000 0.027 0.973
H02.0 Entropion and trichiasis of eyelid
0.000 0.028 0.972
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.028 0.972
J32 Chronic sinusitis
0.000 0.032 0.968
H55-H59 Other disorders of eye and adnexa
0.000 0.032 0.968
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.036 0.964
E10.4 With neurological complications
0.000 0.036 0.964
H02.1 Ectropion of eyelid
0.000 0.037 0.963
J80 Adult respiratory distress syndrome
0.000 0.037 0.963
D50-D53 Nutritional anaemias
0.000 0.041 0.959
J22 Unspecified acute lower respiratory infection
0.000 0.042 0.958
D68 Other coagulation defects
0.000 0.046 0.954
D69 Purpura and other haemorrhagic conditions
0.000 0.047 0.953
M34.9 Systemic sclerosis, unspecified
0.000 0.049 0.951
J84 Other interstitial pulmonary diseases
0.000 0.049 0.951
L40.0 Psoriasis vulgaris
0.948 0.052 0.000
E27 Other disorders of adrenal gland
0.000 0.056 0.944
H57 Other disorders of eye and adnexa
0.000 0.057 0.943
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.061 0.939
M06.0 Seronegative rheumatoid arthritis
0.000 0.062 0.938
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.063 0.937
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.065 0.935
E10.5 With peripheral circulatory complications
0.000 0.066 0.934
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.066 0.934
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.067 0.933
E06 Thyroiditis
0.000 0.071 0.929
E27.1 Primary adrenocortical insufficiency
0.000 0.074 0.926
N48 Other disorders of penis
0.926 0.074 0.000
L30 Other dermatitis
0.000 0.075 0.925
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.076 0.924
L81 Other disorders of pigmentation
0.000 0.079 0.921
N48.6 Balanitis xerotica obliterans
0.919 0.081 0.000
E10.2 With renal complications
0.000 0.083 0.917
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.085 0.915
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.085 0.915
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.086 0.914
D50 Iron deficiency anaemia
0.000 0.088 0.912
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.089 0.911
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.093 0.907
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.100 0.900
L85 Other epidermal thickening
0.000 0.102 0.898
J32.0 Chronic maxillary sinusitis
0.000 0.103 0.897
E07 Other disorders of thyroid
0.000 0.105 0.895
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.105 0.895
H57.0 Anomalies of pupillary function
0.000 0.108 0.892
H06.2 Dysthyroid exophthalmos
0.000 0.111 0.889
D50.8 Other iron deficiency anaemias
0.000 0.112 0.888
N48.8 Other specified disorders of penis
0.884 0.116 0.000
L81.4 Other melanin hyperpigmentation
0.000 0.116 0.884
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.117 0.883
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.117 0.883
J33.8 Other polyp of sinus
0.000 0.119 0.881
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.119 0.881
M35.1 Other overlap syndromes
0.000 0.122 0.878
J95-J99 Other diseases of the respiratory system
0.000 0.123 0.877
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.125 0.875
Chapter VI Diseases of the nervous system
0.000 0.127 0.873
M34.1 CR(E)ST syndrome
0.000 0.128 0.872
E06.3 Autoimmune thyroiditis
0.000 0.128 0.872
N48.0 Leukoplakia of penis
0.865 0.135 0.000
L30.9 Dermatitis, unspecified
0.000 0.135 0.865
D68.8 Other specified coagulation defects
0.000 0.136 0.864
M06.3 Rheumatoid nodule
0.000 0.137 0.863
L29 Pruritus
0.000 0.139 0.861
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.142 0.858
D68.9 Coagulation defect, unspecified
0.000 0.142 0.858
M06.4 Inflammatory polyarthropathy
0.000 0.151 0.849
L85.9 Epidermal thickening, unspecified
0.000 0.153 0.847
L83 Acanthosis nigricans
0.000 0.153 0.847
J32.8 Other chronic sinusitis
0.000 0.154 0.846
J31.0 Chronic rhinitis
0.000 0.156 0.844
J32.9 Chronic sinusitis, unspecified
0.000 0.156 0.844
E29 Testicular dysfunction
0.000 0.157 0.843
H05 Disorders of orbit
0.000 0.158 0.842
H16 Keratitis
0.000 0.158 0.842
J81 Pulmonary oedema
0.000 0.164 0.836
N48.9 Disorder of penis, unspecified
0.833 0.167 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.169 0.831
E28 Ovarian dysfunction
0.000 0.169 0.831
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.169 0.831
L57.0 Actinic keratosis
0.000 0.169 0.831
D68.5 Primary Thrombophilia
0.000 0.170 0.830
M34.8 Other forms of systemic sclerosis
0.000 0.171 0.829
L94 Other localised connective tissue disorders
0.000 0.173 0.827
L93 Lupus erythematosus
0.000 0.174 0.826
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.176 0.824
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.177 0.823
N48.1 Balanoposthitis
0.823 0.177 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.177 0.823
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.178 0.822
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.180 0.820
M32 Systemic lupus erythematosus
0.000 0.182 0.818
L21 Seborrhoeic dermatitis
0.000 0.183 0.817
E07.9 Disorder of thyroid, unspecified
0.000 0.186 0.814
D60-D64 Aplastic and other anaemias
0.000 0.188 0.812
D52 Folate deficiency anaemia
0.000 0.189 0.811
H04.8 Other disorders of lachrymal system
0.000 0.193 0.807
H02.4 Ptosis of eyelid
0.000 0.194 0.806
N48.4 Impotence of organic origin
0.801 0.199 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.000 0.201 0.799
D69.5 Secondary thrombocytopenia
0.000 0.202 0.798
H20 Iridocyclitis
0.000 0.202 0.798
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.202 0.798
E10.8 With unspecified complications
0.000 0.204 0.796
L30.8 Other specified dermatitis
0.000 0.205 0.795
E20 Hypoparathyroidism
0.000 0.207 0.793
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.208 0.792
L29.0 Pruritus ani
0.000 0.208 0.792
D69.0 Allergic purpura
0.000 0.209 0.791
H57.8 Other specified disorders of eye and adnexa
0.000 0.211 0.789
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.215 0.784
H16.0 Corneal ulcer
0.000 0.217 0.783
H55 Nystagmus and other irregular eye movements
0.000 0.218 0.782
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.220 0.780
L40-L45 Papulosquamous disorders
0.492 0.220 0.288
M06.34 Rheumatoid nodule (Hand)
0.000 0.220 0.780
D80-D89 Certain disorders involving the immune mechanism
0.000 0.230 0.769
E05.8 Other thyrotoxicosis
0.000 0.232 0.768
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.232 0.767
J84.8 Other specified interstitial pulmonary diseases
0.000 0.238 0.762
H01 Other inflammation of eyelid
0.000 0.238 0.762
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.238 0.762
H04.1 Other disorders of lachrymal gland
0.000 0.240 0.760
E04 Other non-toxic goitre
0.000 0.243 0.757
L84 Corns and callosities
0.000 0.243 0.757
H02.6 Xanthelasma of eyelid
0.000 0.244 0.756
L40.1 Generalised pustular psoriasis
0.753 0.247 0.000
E10.6 With other specified complications
0.000 0.248 0.752
M35.7 Hypermobility syndrome
0.000 0.249 0.751
L80 Vitiligo
0.000 0.249 0.751
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.250 0.750
D61 Other aplastic anaemias
0.000 0.250 0.750
E27.8 Other specified disorders of adrenal gland
0.000 0.251 0.749
E29.1 Testicular hypofunction
0.000 0.251 0.749
L82 Seborrhoeic keratosis
0.000 0.252 0.748
J20 Acute bronchitis
0.000 0.258 0.742
D68.0 Von Willebrand's disease
0.000 0.258 0.742
H05.0 Acute inflammation of orbit
0.000 0.259 0.741
G37 Other demyelinating diseases of central nervous system
0.000 0.259 0.741
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.266 0.734
L25 Unspecified contact dermatitis
0.000 0.267 0.733
L20 Atopic dermatitis
0.000 0.268 0.732
M60-M63 Disorders of muscles
0.000 0.269 0.731
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.273 0.727
E14 Unspecified diabetes mellitus
0.000 0.275 0.725
L28 Lichen simplex chronicus and prurigo
0.000 0.279 0.721
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.279 0.721
J21 Acute bronchiolitis
0.000 0.281 0.719
M22 Disorders of patella
0.000 0.282 0.718
E26 Hyperaldosteronism
0.000 0.282 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.8 Other specified systemic involvement of connective tissue
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M35.2 Behcet's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M30 Polyarteritis nodosa and related conditions
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H04.9 Disorder of lachrymal system, unspecified
0.000 0.284 0.716
N48.5 Ulcer of penis
0.715 0.285 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.285 0.715
L87 Transepidermal elimination disorders
0.000 0.285 0.715
L88 Pyoderma gangrenosum
0.000 0.285 0.715
L86 Keratoderma in diseases classified elsewhere
0.000 0.285 0.715
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.287 0.713
J32.1 Chronic frontal sinusitis
0.000 0.288 0.711
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.289 0.711
E16 Other disorders of pancreatic internal secretion
0.000 0.291 0.709
D67 Hereditary factor IX deficiency
0.000 0.291 0.709
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.292 0.708
M34.0 Progressive systemic sclerosis
0.000 0.292 0.708
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.292 0.708
L27 Dermatitis due to substances taken internally
0.000 0.292 0.708
D52.9 Folate deficiency anaemia, unspecified
0.000 0.294 0.706
D61.9 Aplastic anaemia, unspecified
0.000 0.294 0.706
J95.8 Other postprocedural respiratory disorders
0.000 0.295 0.705
L93.0 Discoid lupus erythematosus
0.000 0.296 0.704
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.296 0.704
L24 Irritant contact dermatitis
0.000 0.297 0.703
L26 Exfoliative dermatitis
0.000 0.297 0.703
L22 Diaper [napkin] dermatitis
0.000 0.297 0.703
H04.4 Chronic inflammation of lachrymal passages
0.000 0.299 0.701
N40-N51 Diseases of male genital organs
0.700 0.300 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.301 0.699
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.301 0.699
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.301 0.699
L98.1 Factitial dermatitis
0.000 0.301 0.699
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.301 0.699
E32 Diseases of thymus
0.000 0.301 0.699
E31 Polyglandular dysfunction
0.000 0.301 0.699
E30 Disorders of puberty, not elsewhere classified
0.000 0.301 0.699
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.301 0.699
H04.6 Other changes in lachrymal passages
0.000 0.302 0.698
H04.0 Dacryoadenitis
0.000 0.302 0.698
L29.2 Pruritus vulvae
0.000 0.302 0.698
J32.3 Chronic sphenoidal sinusitis
0.000 0.306 0.694
D86 Sarcoidosis
0.000 0.306 0.694
E04.2 Non-toxic multinodular goitre
0.000 0.307 0.693
L58 Radiodermatitis
0.000 0.309 0.691
L55 Sunburn
0.000 0.309 0.691
N47 Redundant prepuce, phimosis and paraphimosis
0.691 0.309 0.000
E06.9 Thyroiditis, unspecified
0.000 0.310 0.690
H30 Chorioretinal inflammation
0.000 0.310 0.689
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.312 0.688
D51 Vitamin B12 deficiency anaemia
0.000 0.312 0.688
M12 Other specific arthropathies
0.000 0.313 0.687
D68.6 Other Thrombophilia
0.000 0.313 0.687
E03.8 Other specified hypothyroidism
0.000 0.313 0.687
L94.0 Localised scleroderma [morphea]
0.000 0.313 0.687
J31.2 Chronic pharyngitis
0.000 0.314 0.686
N48.2 Other inflammatory disorders of penis
0.685 0.314 0.000
D68.4 Acquired coagulation factor deficiency
0.000 0.316 0.684
D69.8 Other specified haemorrhagic conditions
0.000 0.317 0.683
D69.4 Other primary thrombocytopenia
0.000 0.317 0.683
D69.1 Qualitative platelet defects
0.000 0.317 0.683
J32.4 Chronic pansinusitis
0.000 0.317 0.683
J84.0 Alveolar and parietoalveolar conditions
0.000 0.318 0.682
M86-M90 Other osteopathies
0.000 0.319 0.681
E28.2 Polycystic ovarian syndrome
0.000 0.319 0.681
E27.9 Disorder of adrenal gland, unspecified
0.000 0.320 0.680
J35 Chronic diseases of tonsils and adenoids
0.000 0.321 0.679
H53-H54 Visual disturbances and blindness
0.000 0.321 0.679
H05.2 Exophthalmic conditions
0.000 0.321 0.679
H02.2 Lagophthalmos
0.000 0.322 0.678
L57.4 Cutis laxa senilis
0.000 0.322 0.678
J00-J06 Acute upper respiratory infections
0.000 0.322 0.678
E27.5 Adrenomedullary hyperfunction
0.000 0.323 0.677
E27.0 Other adrenocortical overactivity
0.000 0.323 0.677
H20.8 Other iridocyclitis
0.000 0.324 0.676
H02.5 Other disorders affecting eyelid function
0.000 0.325 0.675
D68.1 Hereditary factor XI deficiency
0.000 0.325 0.674
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.327 0.673
L57.5 Actinic granuloma
0.000 0.327 0.673
L57.3 Poikiloderma of Civatte
0.000 0.327 0.673
L57.2 Cutis rhomboidalis nuchae
0.000 0.327 0.673
L57.1 Actinic reticuloid
0.000 0.327 0.673
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.327 0.673
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.327 0.673
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.327 0.673
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.327 0.673
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.327 0.673
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.327 0.673
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.327 0.673
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.327 0.673
E22 Hyperfunction of pituitary gland
0.000 0.328 0.671
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.330 0.670
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.330 0.670
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.330 0.670
E28.3 Primary ovarian failure
0.000 0.331 0.669
G36 Other acute disseminated demyelination
0.000 0.331 0.669
E23.2 Diabetes insipidus
0.000 0.334 0.666
E06.5 Other chronic thyroiditis
0.000 0.334 0.666
E06.4 Drug-induced thyroiditis
0.000 0.334 0.666
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.334 0.666
E06.1 Subacute thyroiditis
0.000 0.334 0.666
E06.0 Acute thyroiditis
0.000 0.334 0.666
L40.8 Other psoriasis
0.665 0.335 0.000
H16.9 Keratitis, unspecified
0.000 0.336 0.664
N48.3 Priapism
0.664 0.336 0.000
L30.5 Pityriasis alba
0.000 0.337 0.663
L30.4 Erythema intertrigo
0.000 0.337 0.663
L30.2 Cutaneous autosensitisation
0.000 0.337 0.663
L30.1 Dyshidrosis [pompholyx]
0.000 0.337 0.663
L30.0 Nummular dermatitis
0.000 0.337 0.663
J37 Chronic laryngitis and laryngotracheitis
0.000 0.337 0.663
M00-M03 Infectious arthropathies
0.000 0.337 0.663
L10-L14 Bullous disorders
0.000 0.337 0.663
L98.5 Mucinosis of skin
0.000 0.337 0.663
D53 Other nutritional anaemias
0.000 0.338 0.662
E20.9 Hypoparathyroidism, unspecified
0.000 0.338 0.662
H18 Other disorders of cornea
0.000 0.339 0.661
J95.0 Tracheostomy malfunction
0.000 0.339 0.661
E23.6 Other disorders of pituitary gland
0.000 0.339 0.661
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.339 0.661
L81.7 Pigmented purpuric dermatosis
0.000 0.340 0.660
L81.6 Other disorders of diminished melanin formation
0.000 0.340 0.660
L81.5 Leukoderma, not elsewhere classified
0.000 0.340 0.660
L81.3 Cafe au lait spots
0.000 0.340 0.660
L81.2 Freckles
0.000 0.340 0.660
L81.1 Chloasma
0.000 0.340 0.660
L81.0 Postinflammatory hyperpigmentation
0.000 0.340 0.660
H40-H42 Glaucoma
0.000 0.340 0.660
E07.8 Other specified disorders of thyroid
0.000 0.340 0.660
M31 Other necrotising vasculopathies
0.000 0.342 0.658
L95.8 Other vasculitis limited to skin
0.000 0.342 0.658
D69.6 Thrombocytopenia, unspecified
0.000 0.343 0.657
J31.1 Chronic nasopharyngitis
0.000 0.345 0.655
E16.2 Hypoglycaemia, unspecified
0.000 0.345 0.655
D50.1 Sideropenic dysphagia
0.000 0.346 0.654
E34 Other endocrine disorders
0.000 0.351 0.649
L81.8 Other specified disorders of pigmentation
0.000 0.351 0.649
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.352 0.648
H17 Corneal scars and opacities
0.000 0.352 0.648
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.352 0.648
H33 Retinal detachments and breaks
0.000 0.353 0.647
H31 Other disorders of choroid
0.000 0.353 0.647
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.353 0.646
L85.3 Xerosis cutis
0.000 0.356 0.644
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.356 0.644
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.356 0.644
L85.0 Acquired ichthyosis
0.000 0.356 0.644
E07.1 Dyshormogenetic goitre
0.000 0.358 0.642
E07.0 Hypersecretion of calcitonin
0.000 0.358 0.642
M22.2 Patellofemoral disorders
0.000 0.360 0.640
E14.3 With ophthalmic complications
0.000 0.360 0.640
D86.9 Sarcoidosis, unspecified
0.000 0.360 0.640
H01.8 Other specified inflammation of eyelid
0.000 0.361 0.639
L95.9 Vasculitis limited to skin, unspecified
0.000 0.361 0.639
E27.2 Addisonian crisis
0.000 0.361 0.638
L94.2 Calcinosis cutis
0.000 0.362 0.637
L08 Other local infections of skin and subcutaneous tissue
0.000 0.364 0.636
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.365 0.635
D62 Acute posthaemorrhagic anaemia
0.000 0.366 0.634
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.366 0.634
H20.9 Iridocyclitis, unspecified
0.000 0.367 0.633
J35.0 Chronic tonsillitis
0.000 0.368 0.632
J60-J70 Lung diseases due to external agents
0.000 0.369 0.631
D69.2 Other nonthrombocytopenic purpura
0.000 0.369 0.630
H57.1 Ocular pain
0.000 0.371 0.629
J96 Respiratory failure, not elsewhere classified
0.000 0.371 0.629
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.372 0.628
H15 Disorders of sclera
0.000 0.373 0.627
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.374 0.626
H33.2 Serous retinal detachment
0.000 0.375 0.625
L23 Allergic contact dermatitis
0.000 0.379 0.620
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.381 0.619
M06.38 Rheumatoid nodule (Other)
0.000 0.381 0.619
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.381 0.619
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.381 0.619
M06.33 Rheumatoid nodule (Forearm)
0.000 0.381 0.619
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.381 0.619
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.381 0.619
L29.1 Pruritus scroti
0.000 0.383 0.617
E65-E68 Obesity and other hyperalimentation
0.000 0.384 0.616
E23.0 Hypopituitarism
0.000 0.385 0.615
J00 Acute nasopharyngitis [common cold]
0.000 0.387 0.613
E23.7 Disorder of pituitary gland, unspecified
0.000 0.388 0.612
M11 Other crystal arthropathies
0.000 0.389 0.611
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.391 0.609
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.391 0.609
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.391 0.609
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.391 0.609
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.391 0.609
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.391 0.609
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.391 0.609
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.391 0.609
E29.9 Testicular dysfunction, unspecified
0.000 0.395 0.604
E29.8 Other testicular dysfunction
0.000 0.395 0.604
E29.0 Testicular hyperfunction
0.000 0.395 0.604
H05.9 Disorder of orbit, unspecified
0.000 0.396 0.604
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.396 0.604
H05.3 Deformity of orbit
0.000 0.396 0.604
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.396 0.604
H16.8 Other keratitis
0.000 0.396 0.603
H16.4 Corneal neovascularisation
0.000 0.396 0.603
H16.3 Interstitial and deep keratitis
0.000 0.396 0.603
H16.1 Other superficial keratitis without conjunctivitis
0.000 0.396 0.603
N45 Orchitis and epididymitis
0.603 0.397 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.397 0.603
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.398 0.602
G90-G99 Other disorders of the nervous system
0.000 0.399 0.601
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.399 0.600
H20.0 Acute and subacute iridocyclitis
0.000 0.401 0.599
M14 Arthropathies in other diseases classified elsewhere
0.000 0.402 0.598
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.402 0.598
L29.8 Other pruritus
0.000 0.402 0.598
H00 Hordeolum and chalazion
0.000 0.402 0.598
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.403 0.597
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.404 0.596
E23.1 Drug-induced hypopituitarism
0.000 0.404 0.596
E28.9 Ovarian dysfunction, unspecified
0.000 0.404 0.596
E28.8 Other ovarian dysfunction
0.000 0.404 0.596
E28.1 Androgen excess
0.000 0.404 0.596
E28.0 Oestrogen excess
0.000 0.404 0.596
E15 Nondiabetic hypoglycaemic coma
0.000 0.404 0.596
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.406 0.593
H05.8 Other disorders of orbit
0.000 0.407 0.593
L94.8 Other specified localised connective tissue disorders
0.000 0.407 0.593
L94.6 Ainhum
0.000 0.407 0.593
L94.5 Poikiloderma vasculare atrophicans
0.000 0.407 0.593
L94.4 Gottron's papules
0.000 0.407 0.593
L94.3 Sclerodactyly
0.000 0.407 0.593
L94.1 Linear scleroderma
0.000 0.407 0.593
L93.2 Other local lupus erythematosus
0.000 0.408 0.592
L93.1 Subacute cutaneous lupus erythematosus
0.000 0.408 0.592
M33 Dermatopolymyositis
0.000 0.408 0.592
D55-D59 Haemolytic anaemias
0.000 0.408 0.592
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.408 0.592
G80 Infantile cerebral palsy
0.000 0.408 0.592
E25 Adrenogenital disorders
0.000 0.408 0.591
H10-H13 Disorders of conjunctiva
0.000 0.409 0.591
J20.9 Acute bronchitis, unspecified
0.000 0.409 0.590
L95.1 Erythema elevatum diutinum
0.000 0.412 0.588
L95.0 Livedoid vasculitis
0.000 0.412 0.588
H16.2 Keratoconjunctivitis
0.000 0.412 0.587
H18.6 Keratoconus
0.000 0.413 0.587
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.413 0.586
M32.8 Other forms of systemic lupus erythematosus
0.000 0.413 0.586
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.413 0.586
L21.8 Other seborrhoeic dermatitis
0.000 0.414 0.585
L21.1 Seborrhoeic infantile dermatitis
0.000 0.414 0.585
L21.0 Seborrhoea capitis
0.000 0.414 0.585

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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