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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28397307
log Bayes Factor = 14.0816
Chromosome 6   position 31,233,651  (GRCh37) Explore rs28397307 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.002 0.998
# Top node
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
D50-D53 Nutritional anaemias
0.000 0.003 0.997
D50 Iron deficiency anaemia
0.000 0.004 0.996
D50.9 Iron deficiency anaemia, unspecified
0.000 0.004 0.996
E10 Insulin-dependent diabetes mellitus
0.000 0.005 0.995
M06 Other rheumatoid arthritis
0.000 0.007 0.993
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.010 0.990
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.011 0.989
E10.9 Without complications
0.000 0.015 0.985
M05-M14 Inflammatory polyarthropathies
0.000 0.019 0.981
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.031 0.969
L08 Other local infections of skin and subcutaneous tissue
0.000 0.040 0.960
D60-D64 Aplastic and other anaemias
0.000 0.042 0.958
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.042 0.958
Chapter I Certain infectious and parasitic diseases
0.000 0.045 0.955
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.054 0.946
N48 Other disorders of penis
0.946 0.054 0.000
N40-N51 Diseases of male genital organs
0.945 0.055 0.000
N43 Hydrocele and spermatocele
0.941 0.059 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.060 0.940
N48.6 Balanitis xerotica obliterans
0.940 0.060 0.000
N43.3 Hydrocele, unspecified
0.939 0.061 0.000
D64 Other anaemias
0.000 0.076 0.924
B35-B49 Mycoses
0.000 0.076 0.924
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.081 0.919
E10.3 With ophthalmic complications
0.000 0.088 0.912
L57.0 Actinic keratosis
0.000 0.089 0.911
B37 Candidiasis
0.000 0.090 0.910
N41 Inflammatory diseases of prostate
0.901 0.099 0.000
D64.9 Anaemia, unspecified
0.000 0.101 0.899
E70-E90 Metabolic disorders
0.000 0.102 0.898
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.103 0.897
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.106 0.894
B37.8 Candidiasis of other sites
0.000 0.111 0.889
M07 Psoriatic and enteropathic arthropathies
0.000 0.113 0.887
Chapter VI Diseases of the nervous system
0.000 0.114 0.886
M06.0 Seronegative rheumatoid arthritis
0.000 0.115 0.885
N48.0 Leukoplakia of penis
0.869 0.131 0.000
E14 Unspecified diabetes mellitus
0.000 0.131 0.869
B25-B34 Other viral diseases
0.000 0.131 0.869
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.133 0.867
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.146 0.854
N50 Other disorders of male genital organs
0.854 0.146 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.146 0.854
E06 Thyroiditis
0.000 0.150 0.850
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.150 0.850
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.150 0.850
M05 Seropositive rheumatoid arthritis
0.000 0.156 0.844
B37.0 Candidal stomatitis
0.000 0.161 0.839
L40.0 Psoriasis vulgaris
0.000 0.162 0.838
E50-E64 Other nutritional deficiencies
0.000 0.167 0.833
G30-G32 Other degenerative diseases of the nervous system
0.000 0.168 0.832
N48.8 Other specified disorders of penis
0.825 0.175 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.176 0.824
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.178 0.822
E89.0 Postprocedural hypothyroidism
0.000 0.178 0.822
N41.9 Inflammatory disease of prostate, unspecified
0.820 0.180 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.181 0.819
M07.3 Other psoriatic arthropathies
0.000 0.181 0.819
E40-E46 Malnutrition
0.000 0.181 0.819
G35 Multiple sclerosis
0.000 0.182 0.818
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.182 0.818
N50.8 Other specified disorders of male genital organs
0.813 0.187 0.000
E86 Volume depletion
0.000 0.191 0.809
B34 Viral infection of unspecified site
0.000 0.192 0.808
N48.2 Other inflammatory disorders of penis
0.789 0.211 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.214 0.786
E10.5 With peripheral circulatory complications
0.000 0.217 0.783
D61 Other aplastic anaemias
0.000 0.221 0.779
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.223 0.777
E14.9 Without complications
0.000 0.224 0.776
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.229 0.771
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.235 0.765
B34.9 Viral infection, unspecified
0.000 0.236 0.764
E11 Non-insulin-dependent diabetes mellitus
0.000 0.239 0.761
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.241 0.759
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.241 0.759
A30-A49 Other bacterial diseases
0.000 0.242 0.758
N42 Other disorders of prostate
0.747 0.253 0.000
N41.0 Acute prostatitis
0.745 0.254 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.255 0.745
E06.3 Autoimmune thyroiditis
0.000 0.257 0.742
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.258 0.742
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.259 0.741
N48.9 Disorder of penis, unspecified
0.739 0.261 0.000
N41.1 Chronic prostatitis
0.738 0.261 0.000
E10.4 With neurological complications
0.000 0.263 0.737
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.263 0.737
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.263 0.737
B35 Dermatophytosis
0.000 0.264 0.736
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.268 0.732
H43-H45 Disorders of vitreous body and globe
0.000 0.268 0.732
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.269 0.731
M11 Other crystal arthropathies
0.000 0.271 0.729
D51 Vitamin B12 deficiency anaemia
0.000 0.273 0.727
N47 Redundant prepuce, phimosis and paraphimosis
0.723 0.277 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.278 0.722
D72 Other disorders of white blood cells
0.000 0.279 0.721
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.282 0.718
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L10-L14 Bullous disorders
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
D55-D59 Haemolytic anaemias
0.000 0.284 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.285 0.715
D53 Other nutritional anaemias
0.000 0.285 0.715
D50.1 Sideropenic dysphagia
0.000 0.286 0.714
E10.8 With unspecified complications
0.000 0.286 0.713
E10.7 With multiple complications
0.000 0.286 0.713
E10.6 With other specified complications
0.000 0.286 0.713
E10.2 With renal complications
0.000 0.286 0.713
E10.0 With coma
0.000 0.286 0.713
M06.8 Other specified rheumatoid arthritis
0.000 0.288 0.712
M06.2 Rheumatoid bursitis
0.000 0.288 0.712
M06.1 Adult-onset Still's disease
0.000 0.288 0.712
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.290 0.710
D52 Folate deficiency anaemia
0.000 0.290 0.710
L04 Acute lymphadenitis
0.000 0.291 0.709
L01 Impetigo
0.000 0.291 0.709
L00 Staphylococcal scalded skin syndrome
0.000 0.291 0.709
M00-M03 Infectious arthropathies
0.000 0.292 0.708
E53 Deficiency of other B group vitamins
0.000 0.292 0.708
M06.4 Inflammatory polyarthropathy
0.000 0.292 0.707
B99-B99 Other infectious diseases
0.000 0.293 0.707
N45 Orchitis and epididymitis
0.706 0.294 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.295 0.705
M12 Other specific arthropathies
0.000 0.296 0.704
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.296 0.704
M08 Juvenile arthritis
0.000 0.296 0.704
N50.9 Disorder of male genital organs, unspecified
0.702 0.298 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.300 0.700
G30 Alzheimer's disease
0.000 0.302 0.698
E10.1 With ketoacidosis
0.000 0.305 0.695
E04 Other non-toxic goitre
0.000 0.305 0.695
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.305 0.694
L58 Radiodermatitis
0.000 0.305 0.694
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.305 0.694
L55 Sunburn
0.000 0.305 0.694
G70-G73 Diseases of myoneural junction and muscle
0.000 0.306 0.694
H43 Disorders of vitreous body
0.000 0.307 0.693
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.307 0.693
E13 Other specified diabetes mellitus
0.000 0.307 0.693
M45-M49 Spondylopathies
0.000 0.307 0.692
E80.4 Gilbert's syndrome
0.000 0.309 0.691
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.310 0.690
E46 Unspecified protein-energy malnutrition
0.000 0.311 0.689
M06.3 Rheumatoid nodule
0.000 0.311 0.689
L08.1 Erythrasma
0.000 0.312 0.688
L08.0 Pyoderma
0.000 0.312 0.688
L20-L30 Dermatitis and eczema
0.000 0.312 0.688
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.313 0.687
A00-A09 Intestinal infectious diseases
0.000 0.313 0.687
M65-M68 Disorders of synovium and tendon
0.000 0.314 0.686
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.315 0.685
B50-B64 Protozoal diseases
0.000 0.315 0.685
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.315 0.685
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.315 0.685
A75-A79 Rickettsioses
0.000 0.315 0.685
A70-A74 Other diseases caused by chlamydiae
0.000 0.315 0.685
A65-A69 Other spirochaetal diseases
0.000 0.315 0.685
A20-A28 Certain zoonotic bacterial diseases
0.000 0.315 0.685
A15-A19 Tuberculosis
0.000 0.315 0.685
L05 Pilonidal cyst
0.000 0.315 0.685
B37.3 Candidiasis of vulva and vagina
0.000 0.321 0.679
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.321 0.678
L57.5 Actinic granuloma
0.000 0.321 0.678
L57.4 Cutis laxa senilis
0.000 0.321 0.678
L57.3 Poikiloderma of Civatte
0.000 0.321 0.678
L57.2 Cutis rhomboidalis nuchae
0.000 0.321 0.678
L57.1 Actinic reticuloid
0.000 0.321 0.678
N48.5 Ulcer of penis
0.678 0.322 0.000
N48.3 Priapism
0.678 0.322 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.677 0.323 0.000
N46 Male infertility
0.677 0.323 0.000
N44 Torsion of testis
0.677 0.323 0.000
D75 Other diseases of blood and blood-forming organs
0.000 0.323 0.677
E05.9 Thyrotoxicosis, unspecified
0.000 0.324 0.676
N43.4 Spermatocele
0.675 0.325 0.000
N43.2 Other hydrocele
0.675 0.325 0.000
N43.1 Infected hydrocele
0.675 0.325 0.000
N43.0 Encysted hydrocele
0.675 0.325 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.326 0.674
B15-B19 Viral hepatitis
0.000 0.327 0.673
E11.3 With ophthalmic complications
0.000 0.330 0.670
B65-B83 Helminthiases
0.000 0.330 0.669
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.331 0.669
E88 Other metabolic disorders
0.000 0.333 0.667
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.334 0.666
G62 Other polyneuropathies
0.000 0.335 0.665
D64.8 Other specified anaemias
0.000 0.337 0.662
D64.4 Congenital dyserythropoietic anaemia
0.000 0.337 0.662
D64.3 Other sideroblastic anaemias
0.000 0.337 0.662
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.337 0.662
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.337 0.662
D64.0 Hereditary sideroblastic anaemia
0.000 0.337 0.662
B48 Other mycoses, not elsewhere classified
0.000 0.338 0.662
B47 Mycetoma
0.000 0.338 0.662
B46 Zygomycosis
0.000 0.338 0.662
B45 Cryptococcosis
0.000 0.338 0.662
B43 Chromomycosis and phaeomycotic abscess
0.000 0.338 0.662
B42 Sporotrichosis
0.000 0.338 0.662
B41 Paracoccidioidomycosis
0.000 0.338 0.662
B40 Blastomycosis
0.000 0.338 0.662
B39 Histoplasmosis
0.000 0.338 0.662
B38 Coccidioidomycosis
0.000 0.338 0.662
B36 Other superficial mycoses
0.000 0.338 0.662
N42.8 Other specified disorders of prostate
0.662 0.338 0.000
H53-H54 Visual disturbances and blindness
0.000 0.342 0.658
E07 Other disorders of thyroid
0.000 0.343 0.657
M45 Ankylosing spondylitis
0.000 0.344 0.656
G31.8 Other specified degenerative diseases of nervous system
0.000 0.344 0.656
G37 Other demyelinating diseases of central nervous system
0.000 0.346 0.654
B37.7 Candidal septicaemia
0.000 0.347 0.653
B37.6 Candidal endocarditis
0.000 0.347 0.653
B37.5 Candidal meningitis
0.000 0.347 0.653
B37.4 Candidiasis of other urogenital sites
0.000 0.347 0.653
B37.2 Candidiasis of skin and nail
0.000 0.347 0.653
B37.1 Pulmonary candidiasis
0.000 0.347 0.653
H40-H42 Glaucoma
0.000 0.350 0.650
D61.9 Aplastic anaemia, unspecified
0.000 0.350 0.650
D73 Diseases of spleen
0.000 0.350 0.650
N41.8 Other inflammatory diseases of prostate
0.646 0.354 0.000
N41.3 Prostatocystitis
0.646 0.354 0.000
N41.2 Abscess of prostate
0.646 0.354 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.355 0.645
E84 Cystic fibrosis
0.000 0.356 0.643
E79 Disorders of purine and pyrimidine metabolism
0.000 0.356 0.643
E77 Disorders of glycoprotein metabolism
0.000 0.356 0.643
E76 Disorders of glycosaminoglycan metabolism
0.000 0.356 0.643
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.356 0.643
E73 Lactose intolerance
0.000 0.356 0.643
E72 Other disorders of amino-acid metabolism
0.000 0.356 0.643
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.356 0.643
E70 Disorders of aromatic amino-acid metabolism
0.000 0.356 0.643
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.356 0.643
E65-E68 Obesity and other hyperalimentation
0.000 0.359 0.641
M80-M85 Disorders of bone density and structure
0.000 0.363 0.637
M07.6 Other enteropathic arthropathies
0.000 0.364 0.636
M07.5 Arthropathy in ulcerative colitis
0.000 0.364 0.636
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.364 0.636
M07.2 Psoriatic spondylitis
0.000 0.364 0.636
M07.1 Arthritis mutilans
0.000 0.364 0.636
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.364 0.636
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.365 0.635
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.365 0.635
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.365 0.635
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.365 0.635
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.365 0.635
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.365 0.635
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.365 0.635
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.365 0.635
M10 Gout
0.000 0.366 0.634
M60-M63 Disorders of muscles
0.000 0.367 0.633
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.369 0.631
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.369 0.631
D72.8 Other specified disorders of white blood cells
0.000 0.369 0.631
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.630 0.370 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.370 0.630
L81 Other disorders of pigmentation
0.000 0.371 0.629
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.372 0.627
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.374 0.626
N48.4 Impotence of organic origin
0.624 0.376 0.000
E14.3 With ophthalmic complications
0.000 0.377 0.623
E14.8 With unspecified complications
0.000 0.377 0.623
E14.7 With multiple complications
0.000 0.377 0.623
E14.6 With other specified complications
0.000 0.377 0.623
E14.5 With peripheral circulatory complications
0.000 0.377 0.623
E14.4 With neurological complications
0.000 0.377 0.623
E14.2 Withrenal complications
0.000 0.377 0.623
E14.1 With ketoacidosis
0.000 0.377 0.623
E14.0 With coma
0.000 0.377 0.623
B33 Other viral diseases, not elsewhere classified
0.000 0.377 0.623
B30 Viral conjunctivitis
0.000 0.377 0.623
B27 Infectious mononucleosis
0.000 0.377 0.623
B26 Mumps
0.000 0.377 0.623
B25 Cytomegaloviral disease
0.000 0.377 0.623
E53.8 Deficiency of other specified B group vitamins
0.000 0.382 0.618
L03 Cellulitis
0.000 0.383 0.617
E89.3 Postprocedural hypopituitarism
0.000 0.384 0.616
E74 Other disorders of carbohydrate metabolism
0.000 0.385 0.615
A80-A89 Viral infections of the central nervous system
0.000 0.386 0.614
H43.3 Other vitreous opacities
0.000 0.386 0.614
D62 Acute posthaemorrhagic anaemia
0.000 0.387 0.613
E05.5 Thyroid crisis or storm
0.000 0.387 0.612
E05.4 Thyrotoxicosis factitia
0.000 0.387 0.612
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.387 0.612
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.387 0.612
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.387 0.612
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.388 0.612
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.388 0.612
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.388 0.612
E89.5 Postprocedural testicular hypofunction
0.000 0.388 0.612
E89.4 Postprocedural ovarian failure
0.000 0.388 0.612
E89.2 Postprocedural hypoparathyroidism
0.000 0.388 0.612
E89.1 Postprocedural hypoinsulinaemia
0.000 0.388 0.612
H30-H36 Disorders of choroid and retina
0.000 0.389 0.611
E06.9 Thyroiditis, unspecified
0.000 0.390 0.609
E06.5 Other chronic thyroiditis
0.000 0.390 0.609
E06.4 Drug-induced thyroiditis
0.000 0.390 0.609
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.390 0.609
E06.1 Subacute thyroiditis
0.000 0.390 0.609
E06.0 Acute thyroiditis
0.000 0.390 0.609
D74 Methaemoglobinaemia
0.000 0.391 0.609
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.391 0.609
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.391 0.609
G36 Other acute disseminated demyelination
0.000 0.391 0.609
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.391 0.609
H43.8 Other disorders of vitreous body
0.000 0.392 0.608
Chapter XXII Codes for special purposes
0.000 0.392 0.608
E61 Deficiency of other nutrient elements
0.000 0.393 0.607
M05.8 Other seropositive rheumatoid arthritis
0.000 0.395 0.605
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.395 0.605
M05.2 Rheumatoid vasculitis
0.000 0.395 0.605
M05.1 Rheumatoid lung disease
0.000 0.395 0.605
M05.0 Felty's syndrome
0.000 0.395 0.605
G62.9 Polyneuropathy, unspecified
0.000 0.397 0.603
G30.9 Alzheimer's disease, unspecified
0.000 0.398 0.602
M91-M94 Chondropathies
0.000 0.398 0.602
B35.3 Tinea pedis
0.000 0.398 0.602
G70 Myasthenia gravis and other myoneural disorders
0.000 0.401 0.599
E55 Vitamin D deficiency
0.000 0.401 0.599
E04.2 Non-toxic multinodular goitre
0.000 0.401 0.598
A41 Other septicaemia
0.000 0.402 0.598
L42 Pityriasis rosea
0.000 0.402 0.598
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.403 0.597
E63 Other nutritional deficiencies
0.000 0.403 0.597
E56 Other vitamin deficiencies
0.000 0.403 0.597
E51 Thiamine deficiency
0.000 0.403 0.597
E50 Vitamin A deficiency
0.000 0.403 0.597
E60 Dietary zinc deficiency
0.000 0.403 0.597
E59 Dietary selenium deficiency
0.000 0.403 0.597
E58 Dietary calcium deficiency
0.000 0.403 0.597
E54 Ascorbic acid deficiency
0.000 0.403 0.597
E52 Niacin deficiency [pellagra]
0.000 0.403 0.597
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.403 0.597
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.404 0.596
A46 Erysipelas
0.000 0.409 0.591
H36 Retinal disorders in diseases classified elsewhere
0.000 0.411 0.589
M07.38 Other psoriatic arthropathies (Other)
0.000 0.413 0.587
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.413 0.587
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.413 0.587
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.413 0.587
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.413 0.587
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.413 0.587
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.413 0.587
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.413 0.587
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.413 0.587
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.413 0.587
E45 Retarded development following protein-energy malnutrition
0.000 0.413 0.587
E43 Unspecified severe protein-energy malnutrition
0.000 0.413 0.587
E42 Marasmic kwashiorkor
0.000 0.413 0.587
E41 Nutritional marasmus
0.000 0.413 0.587
E40 Kwashiorkor
0.000 0.413 0.587
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.413 0.587
L43 Lichen planus
0.000 0.414 0.586
E11.1 With ketoacidosis
0.000 0.414 0.586
L85 Other epidermal thickening
0.000 0.415 0.585
L91 Hypertrophic disorders of skin
0.000 0.416 0.584
H53 Visual disturbances
0.000 0.416 0.584
B34.8 Other viral infections of unspecified site
0.000 0.421 0.579
B34.4 Papovirus infection, unspecified
0.000 0.421 0.579
B34.3 Parvovirus infection, unspecified
0.000 0.421 0.579
B34.2 Coronavirus infection, unspecified
0.000 0.421 0.579
B34.1 Enterovirus infection, unspecified
0.000 0.421 0.579
B34.0 Adenovirus infection, unspecified
0.000 0.421 0.579
D50.8 Other iron deficiency anaemias
0.000 0.422 0.578
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.424 0.576
N50.0 Atrophy of testis
0.575 0.425 0.000
B49 Unspecified mycosis
0.000 0.425 0.574
M65 Synovitis and tenosynovitis
0.000 0.426 0.574
H36.0 Diabetic retinopathy
0.000 0.426 0.574
M80 Osteoporosis with pathological fracture
0.000 0.426 0.573
L81.4 Other melanin hyperpigmentation
0.000 0.427 0.573
D70 Agranulocytosis
0.000 0.427 0.573
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.428 0.572
L50-L54 Urticaria and erythema
0.000 0.437 0.562
H10-H13 Disorders of conjunctiva
0.000 0.439 0.561
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.439 0.561
D61.8 Other specified aplastic anaemias
0.000 0.442 0.558
D61.3 Idiopathic aplastic anaemia
0.000 0.442 0.558
D61.2 Aplastic anaemia due to other external agents
0.000 0.442 0.558
D61.1 Drug-induced aplastic anaemia
0.000 0.442 0.558
D61.0 Constitutional aplastic anaemia
0.000 0.442 0.558
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.442 0.557
E80.6 Other disorders of bilirubin metabolism
0.000 0.442 0.557
E80.5 Crigler-Najjar syndrome
0.000 0.442 0.557
E80.3 Defects of catalase and peroxydase
0.000 0.442 0.557
E80.2 Other porphyria
0.000 0.442 0.557
E80.1 Porphyria cutanea tarda
0.000 0.442 0.557
E80.0 Hereditary erythropoietic porphyria
0.000 0.442 0.557
D75.1 Secondary polycythaemia
0.000 0.443 0.557
G80 Infantile cerebral palsy
0.000 0.443 0.557
L29 Pruritus
0.000 0.444 0.556
C44 Other malignant neoplasms of skin
0.000 0.444 0.556
D86 Sarcoidosis
0.000 0.447 0.553
H40 Glaucoma
0.000 0.448 0.552
L83 Acanthosis nigricans
0.000 0.448 0.552
M11.2 Other chondrocalcinosis
0.000 0.451 0.549
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.451 0.549
G31.2 Degeneration of nervous system due to alcohol
0.000 0.451 0.548
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.451 0.548
G31.0 Circumscribed brain atrophy
0.000 0.451 0.548
E11.2 With renal complications
0.000 0.452 0.548
E11.0 With coma
0.000 0.452 0.548
M95.0 Acquired deformity of nose
0.000 0.453 0.547
L89 Decubitus ulcer
0.000 0.453 0.547
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.453 0.547
E11.8 With unspecified complications
0.000 0.454 0.546
E11.7 With multiple complications
0.000 0.454 0.546
L05.0 Pilonidal cyst with abscess
0.000 0.455 0.545
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.455 0.545
G81 Hemiplegia
0.000 0.455 0.545
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.456 0.543
E11.9 Without complications
0.000 0.456 0.544
A48 Other bacterial diseases, not elsewhere classified
0.000 0.457 0.543
A44 Bartonellosis
0.000 0.457 0.543
A43 Nocardiosis
0.000 0.457 0.543
A42 Actinomycosis
0.000 0.457 0.543
A39 Meningococcal infection
0.000 0.457 0.543
A37 Whooping cough
0.000 0.457 0.543
A36 Diphtheria
0.000 0.457 0.543
A32 Listeriosis
0.000 0.457 0.543
A31 Infection due to other mycobacteria
0.000 0.457 0.543
A30 Leprosy [Hansen's disease]
0.000 0.457 0.543
A38 Scarlet fever
0.000 0.457 0.543
A35 Other tetanus
0.000 0.457 0.543
A34 Obstetrical tetanus
0.000 0.457 0.543
A33 Tetanus neonatorum
0.000 0.457 0.543
C44.1 Skin of eyelid, including canthus
0.000 0.458 0.542
M86-M90 Other osteopathies
0.000 0.459 0.541
E85 Amyloidosis
0.000 0.459 0.540
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.460 0.540
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.461 0.539
A08 Viral and other specified intestinal infections
0.000 0.462 0.538
C44.3 Skin of other and unspecified parts of face
0.000 0.462 0.538
E11.6 With other specified complications
0.000 0.462 0.538
A49 Bacterial infection of unspecified site
0.000 0.462 0.538
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.000 0.463 0.537
H43.1 Vitreous haemorrhage
0.000 0.463 0.537
N42.3 Dysplasia of prostate
0.536 0.464 0.000
N42.0 Calculus of prostate
0.536 0.464 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.535 0.465 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.466 0.534
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.466 0.534
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.466 0.534
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.466 0.534
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.466 0.534
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.466 0.534
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.466 0.534
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.466 0.534
G90-G99 Other disorders of the nervous system
0.000 0.466 0.534
C44.4 Skin of scalp and neck
0.000 0.467 0.533
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.467 0.533
L03.3 Cellulitis of trunk
0.000 0.467 0.533
H53.2 Diplopia
0.000 0.468 0.532
C44.7 Skin of lower limb, including hip
0.000 0.468 0.532
H02 Other disorders of eyelid
0.000 0.468 0.532
G70.0 Myasthenia gravis
0.000 0.469 0.531
B99 Other and unspecified infectious diseases
0.000 0.471 0.529
M46 Other inflammatory spondylopathies
0.000 0.471 0.529
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.471 0.529
G64 Other disorders of peripheral nervous system
0.000 0.472 0.528
M00 Pyogenic arthritis
0.000 0.472 0.528
M99 Biomechanical lesions, not elsewhere classified
0.000 0.472 0.528
B35.9 Dermatophytosis, unspecified
0.000 0.472 0.528
B35.8 Other dermatophytoses
0.000 0.472 0.528
B35.6 Tinea cruris
0.000 0.472 0.528
B35.5 Tinea imbricata
0.000 0.472 0.528

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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