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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28397309
log Bayes Factor = 14.234
Chromosome 6   position 31,234,438  (GRCh37) Explore rs28397309 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
# Top node
0.000 0.001 0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
D50-D53 Nutritional anaemias
0.000 0.004 0.996
E10 Insulin-dependent diabetes mellitus
0.000 0.004 0.996
D50 Iron deficiency anaemia
0.000 0.006 0.994
D50.9 Iron deficiency anaemia, unspecified
0.000 0.007 0.993
M06 Other rheumatoid arthritis
0.000 0.008 0.992
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.010 0.990
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.011 0.989
E10.9 Without complications
0.000 0.014 0.986
D60-D64 Aplastic and other anaemias
0.000 0.018 0.982
M05-M14 Inflammatory polyarthropathies
0.000 0.021 0.979
D64 Other anaemias
0.000 0.032 0.968
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.033 0.967
L08 Other local infections of skin and subcutaneous tissue
0.000 0.036 0.964
D64.9 Anaemia, unspecified
0.000 0.043 0.957
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.047 0.953
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.056 0.944
Chapter I Certain infectious and parasitic diseases
0.000 0.060 0.940
Chapter VI Diseases of the nervous system
0.000 0.061 0.939
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.063 0.937
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.071 0.929
E10.3 With ophthalmic complications
0.000 0.086 0.914
N48 Other disorders of penis
0.912 0.088 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.092 0.908
N40-N51 Diseases of male genital organs
0.908 0.092 0.000
L57.0 Actinic keratosis
0.000 0.093 0.907
N48.6 Balanitis xerotica obliterans
0.907 0.093 0.000
E70-E90 Metabolic disorders
0.000 0.095 0.905
N43 Hydrocele and spermatocele
0.902 0.098 0.000
N43.3 Hydrocele, unspecified
0.898 0.102 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.102 0.898
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.105 0.895
B35-B49 Mycoses
0.000 0.106 0.894
M06.0 Seronegative rheumatoid arthritis
0.000 0.115 0.885
M07 Psoriatic and enteropathic arthropathies
0.000 0.117 0.883
G35 Multiple sclerosis
0.000 0.120 0.880
G30-G32 Other degenerative diseases of the nervous system
0.000 0.124 0.876
B37 Candidiasis
0.000 0.124 0.876
E14 Unspecified diabetes mellitus
0.000 0.126 0.874
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.129 0.871
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.131 0.869
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.134 0.866
B25-B34 Other viral diseases
0.000 0.142 0.858
N41 Inflammatory diseases of prostate
0.856 0.144 0.000
E06 Thyroiditis
0.000 0.149 0.851
B37.8 Candidiasis of other sites
0.000 0.151 0.849
M05 Seropositive rheumatoid arthritis
0.000 0.157 0.843
E89.0 Postprocedural hypothyroidism
0.000 0.158 0.842
L40.0 Psoriasis vulgaris
0.000 0.162 0.838
N48.0 Leukoplakia of penis
0.838 0.162 0.000
N48.8 Other specified disorders of penis
0.824 0.176 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.176 0.824
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.177 0.823
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.178 0.822
E86 Volume depletion
0.000 0.178 0.822
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.179 0.821
E40-E46 Malnutrition
0.000 0.180 0.820
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.181 0.818
N50 Other disorders of male genital organs
0.816 0.184 0.000
M07.3 Other psoriatic arthropathies
0.000 0.185 0.815
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.187 0.813
B37.0 Candidal stomatitis
0.000 0.191 0.809
E50-E64 Other nutritional deficiencies
0.000 0.192 0.808
B34 Viral infection of unspecified site
0.000 0.201 0.799
D61 Other aplastic anaemias
0.000 0.202 0.797
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.213 0.787
Chapter VII Diseases of the eye and adnexa
0.000 0.214 0.786
E14.9 Without complications
0.000 0.215 0.785
E10.5 With peripheral circulatory complications
0.000 0.216 0.784
N41.9 Inflammatory disease of prostate, unspecified
0.778 0.222 0.000
N50.8 Other specified disorders of male genital organs
0.778 0.222 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.225 0.775
A30-A49 Other bacterial diseases
0.000 0.229 0.771
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.230 0.770
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.234 0.766
N48.2 Other inflammatory disorders of penis
0.760 0.240 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.241 0.759
B34.9 Viral infection, unspecified
0.000 0.243 0.757
G62 Other polyneuropathies
0.000 0.248 0.752
G30 Alzheimer's disease
0.000 0.250 0.750
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.255 0.745
E06.3 Autoimmune thyroiditis
0.000 0.256 0.744
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.259 0.741
E10.4 With neurological complications
0.000 0.262 0.738
G70-G73 Diseases of myoneural junction and muscle
0.000 0.263 0.737
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.263 0.736
E11 Non-insulin-dependent diabetes mellitus
0.000 0.265 0.735
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.268 0.732
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.268 0.732
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.269 0.731
M11 Other crystal arthropathies
0.000 0.271 0.728
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.272 0.728
D51 Vitamin B12 deficiency anaemia
0.000 0.273 0.727
H43-H45 Disorders of vitreous body and globe
0.000 0.278 0.722
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.281 0.719
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
L10-L14 Bullous disorders
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.284 0.716
D55-D59 Haemolytic anaemias
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
D53 Other nutritional anaemias
0.000 0.286 0.714
E10.8 With unspecified complications
0.000 0.286 0.714
E10.7 With multiple complications
0.000 0.286 0.714
E10.6 With other specified complications
0.000 0.286 0.714
E10.2 With renal complications
0.000 0.286 0.714
E10.0 With coma
0.000 0.286 0.714
N47 Redundant prepuce, phimosis and paraphimosis
0.714 0.286 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.286 0.713
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.287 0.713
D50.1 Sideropenic dysphagia
0.000 0.287 0.713
N48.9 Disorder of penis, unspecified
0.713 0.287 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.289 0.711
M06.2 Rheumatoid bursitis
0.000 0.289 0.711
M06.1 Adult-onset Still's disease
0.000 0.289 0.711
E05.9 Thyrotoxicosis, unspecified
0.000 0.289 0.711
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.289 0.710
D52 Folate deficiency anaemia
0.000 0.290 0.710
L04 Acute lymphadenitis
0.000 0.291 0.709
L01 Impetigo
0.000 0.291 0.709
L00 Staphylococcal scalded skin syndrome
0.000 0.291 0.709
N41.0 Acute prostatitis
0.708 0.292 0.000
M45-M49 Spondylopathies
0.000 0.292 0.707
A00-A09 Intestinal infectious diseases
0.000 0.293 0.707
M06.4 Inflammatory polyarthropathy
0.000 0.294 0.705
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.295 0.705
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.296 0.704
M00-M03 Infectious arthropathies
0.000 0.296 0.704
M12 Other specific arthropathies
0.000 0.298 0.702
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.298 0.702
M08 Juvenile arthritis
0.000 0.298 0.702
G62.9 Polyneuropathy, unspecified
0.000 0.300 0.700
G37 Other demyelinating diseases of central nervous system
0.000 0.300 0.700
M14 Arthropathies in other diseases classified elsewhere
0.000 0.301 0.699
D72 Other disorders of white blood cells
0.000 0.302 0.697
E10.1 With ketoacidosis
0.000 0.303 0.697
N42 Other disorders of prostate
0.697 0.303 0.000
B99-B99 Other infectious diseases
0.000 0.304 0.696
B35 Dermatophytosis
0.000 0.304 0.696
D64.8 Other specified anaemias
0.000 0.306 0.694
D64.4 Congenital dyserythropoietic anaemia
0.000 0.306 0.694
D64.3 Other sideroblastic anaemias
0.000 0.306 0.694
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.306 0.694
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.306 0.694
D64.0 Hereditary sideroblastic anaemia
0.000 0.306 0.694
E13 Other specified diabetes mellitus
0.000 0.306 0.694
L20-L30 Dermatitis and eczema
0.000 0.306 0.694
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.306 0.693
L58 Radiodermatitis
0.000 0.306 0.693
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.306 0.693
L55 Sunburn
0.000 0.306 0.693
L08.1 Erythrasma
0.000 0.309 0.691
L08.0 Pyoderma
0.000 0.309 0.691
E46 Unspecified protein-energy malnutrition
0.000 0.310 0.690
M06.3 Rheumatoid nodule
0.000 0.312 0.688
H53-H54 Visual disturbances and blindness
0.000 0.314 0.686
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.323 0.677
L57.5 Actinic granuloma
0.000 0.323 0.677
L57.4 Cutis laxa senilis
0.000 0.323 0.677
L57.3 Poikiloderma of Civatte
0.000 0.323 0.677
L57.2 Cutis rhomboidalis nuchae
0.000 0.323 0.677
L57.1 Actinic reticuloid
0.000 0.323 0.677
E04 Other non-toxic goitre
0.000 0.323 0.677
H43 Disorders of vitreous body
0.000 0.324 0.676
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.326 0.674
B50-B64 Protozoal diseases
0.000 0.326 0.674
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.326 0.674
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.326 0.674
A75-A79 Rickettsioses
0.000 0.326 0.674
A70-A74 Other diseases caused by chlamydiae
0.000 0.326 0.674
A65-A69 Other spirochaetal diseases
0.000 0.326 0.674
A20-A28 Certain zoonotic bacterial diseases
0.000 0.326 0.674
A15-A19 Tuberculosis
0.000 0.326 0.674
G31.8 Other specified degenerative diseases of nervous system
0.000 0.326 0.674
E80.4 Gilbert's syndrome
0.000 0.326 0.674
E88 Other metabolic disorders
0.000 0.327 0.673
D80-D89 Certain disorders involving the immune mechanism
0.000 0.327 0.673
L05 Pilonidal cyst
0.000 0.327 0.672
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.328 0.672
N50.9 Disorder of male genital organs, unspecified
0.671 0.329 0.000
M45 Ankylosing spondylitis
0.000 0.329 0.671
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.331 0.669
N41.1 Chronic prostatitis
0.666 0.334 0.000
D61.9 Aplastic anaemia, unspecified
0.000 0.335 0.665
B15-B19 Viral hepatitis
0.000 0.337 0.663
E53 Deficiency of other B group vitamins
0.000 0.338 0.662
G30.9 Alzheimer's disease, unspecified
0.000 0.340 0.660
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.340 0.660
M65-M68 Disorders of synovium and tendon
0.000 0.341 0.659
E07 Other disorders of thyroid
0.000 0.342 0.658
B65-B83 Helminthiases
0.000 0.342 0.658
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.343 0.656
N48.5 Ulcer of penis
0.654 0.346 0.000
N48.3 Priapism
0.654 0.346 0.000
D50.8 Other iron deficiency anaemias
0.000 0.347 0.653
G36 Other acute disseminated demyelination
0.000 0.349 0.651
N51 Disorders of male genital organs in diseases classified elsewhere
0.651 0.349 0.000
N46 Male infertility
0.651 0.349 0.000
N44 Torsion of testis
0.651 0.349 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.350 0.650
E84 Cystic fibrosis
0.000 0.351 0.649
E79 Disorders of purine and pyrimidine metabolism
0.000 0.351 0.649
E77 Disorders of glycoprotein metabolism
0.000 0.351 0.649
E76 Disorders of glycosaminoglycan metabolism
0.000 0.351 0.649
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.351 0.649
E73 Lactose intolerance
0.000 0.351 0.649
E72 Other disorders of amino-acid metabolism
0.000 0.351 0.649
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.351 0.649
E70 Disorders of aromatic amino-acid metabolism
0.000 0.351 0.649
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.351 0.649
E11.3 With ophthalmic complications
0.000 0.352 0.648
N43.4 Spermatocele
0.647 0.353 0.000
N43.2 Other hydrocele
0.647 0.353 0.000
N43.1 Infected hydrocele
0.647 0.353 0.000
N43.0 Encysted hydrocele
0.647 0.353 0.000
M10 Gout
0.000 0.353 0.646
D73 Diseases of spleen
0.000 0.354 0.646
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.354 0.646
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.355 0.645
N45 Orchitis and epididymitis
0.644 0.356 0.000
D75 Other diseases of blood and blood-forming organs
0.000 0.359 0.641
B48 Other mycoses, not elsewhere classified
0.000 0.359 0.641
B47 Mycetoma
0.000 0.359 0.641
B46 Zygomycosis
0.000 0.359 0.641
B45 Cryptococcosis
0.000 0.359 0.641
B43 Chromomycosis and phaeomycotic abscess
0.000 0.359 0.641
B42 Sporotrichosis
0.000 0.359 0.641
B41 Paracoccidioidomycosis
0.000 0.359 0.641
B40 Blastomycosis
0.000 0.359 0.641
B39 Histoplasmosis
0.000 0.359 0.641
B38 Coccidioidomycosis
0.000 0.359 0.641
B36 Other superficial mycoses
0.000 0.359 0.641
L81 Other disorders of pigmentation
0.000 0.362 0.638
G70 Myasthenia gravis and other myoneural disorders
0.000 0.363 0.636
H40-H42 Glaucoma
0.000 0.365 0.635
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.365 0.635
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.365 0.635
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.365 0.635
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.365 0.635
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.365 0.635
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.365 0.635
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.365 0.635
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.365 0.635
M07.6 Other enteropathic arthropathies
0.000 0.366 0.633
M07.5 Arthropathy in ulcerative colitis
0.000 0.366 0.633
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.366 0.633
M07.2 Psoriatic spondylitis
0.000 0.366 0.633
M07.1 Arthritis mutilans
0.000 0.366 0.633
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.366 0.633
B37.3 Candidiasis of vulva and vagina
0.000 0.367 0.633
M80-M85 Disorders of bone density and structure
0.000 0.368 0.632
A41 Other septicaemia
0.000 0.369 0.631
D62 Acute posthaemorrhagic anaemia
0.000 0.370 0.630
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.370 0.630
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.372 0.628
E14.3 With ophthalmic complications
0.000 0.372 0.628
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.372 0.628
B37.7 Candidal septicaemia
0.000 0.372 0.628
B37.6 Candidal endocarditis
0.000 0.372 0.628
B37.5 Candidal meningitis
0.000 0.372 0.628
B37.4 Candidiasis of other urogenital sites
0.000 0.372 0.628
B37.2 Candidiasis of skin and nail
0.000 0.372 0.628
B37.1 Pulmonary candidiasis
0.000 0.372 0.628
H53 Visual disturbances
0.000 0.373 0.627
E89.3 Postprocedural hypopituitarism
0.000 0.373 0.627
E14.8 With unspecified complications
0.000 0.373 0.627
E14.7 With multiple complications
0.000 0.373 0.627
E14.6 With other specified complications
0.000 0.373 0.627
E14.5 With peripheral circulatory complications
0.000 0.373 0.627
E14.4 With neurological complications
0.000 0.373 0.627
E14.2 Withrenal complications
0.000 0.373 0.627
E14.1 With ketoacidosis
0.000 0.373 0.627
E14.0 With coma
0.000 0.373 0.627
E05.5 Thyroid crisis or storm
0.000 0.376 0.624
E05.4 Thyrotoxicosis factitia
0.000 0.376 0.624
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.376 0.624
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.376 0.624
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.376 0.624
G90-G99 Other disorders of the nervous system
0.000 0.376 0.624
M60-M63 Disorders of muscles
0.000 0.376 0.623
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.377 0.623
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.377 0.623
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.377 0.623
E89.5 Postprocedural testicular hypofunction
0.000 0.377 0.623
E89.4 Postprocedural ovarian failure
0.000 0.377 0.623
E89.2 Postprocedural hypoparathyroidism
0.000 0.377 0.623
E89.1 Postprocedural hypoinsulinaemia
0.000 0.377 0.623
E74 Other disorders of carbohydrate metabolism
0.000 0.380 0.620
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.380 0.620
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.380 0.620
L91 Hypertrophic disorders of skin
0.000 0.383 0.617
B33 Other viral diseases, not elsewhere classified
0.000 0.385 0.615
B30 Viral conjunctivitis
0.000 0.385 0.615
B27 Infectious mononucleosis
0.000 0.385 0.615
B26 Mumps
0.000 0.385 0.615
B25 Cytomegaloviral disease
0.000 0.385 0.615
N41.8 Other inflammatory diseases of prostate
0.613 0.386 0.000
N41.3 Prostatocystitis
0.613 0.386 0.000
N41.2 Abscess of prostate
0.613 0.386 0.000
D72.8 Other specified disorders of white blood cells
0.000 0.389 0.611
E06.9 Thyroiditis, unspecified
0.000 0.390 0.610
E06.5 Other chronic thyroiditis
0.000 0.390 0.610
E06.4 Drug-induced thyroiditis
0.000 0.390 0.610
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.390 0.610
E06.1 Subacute thyroiditis
0.000 0.390 0.610
E06.0 Acute thyroiditis
0.000 0.390 0.610
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.605 0.395 0.000
A80-A89 Viral infections of the central nervous system
0.000 0.395 0.605
N42.8 Other specified disorders of prostate
0.605 0.395 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.396 0.604
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.396 0.604
M05.2 Rheumatoid vasculitis
0.000 0.396 0.604
M05.1 Rheumatoid lung disease
0.000 0.396 0.604
M05.0 Felty's syndrome
0.000 0.396 0.604
A46 Erysipelas
0.000 0.399 0.601
N48.4 Impotence of organic origin
0.600 0.400 0.000
H43.3 Other vitreous opacities
0.000 0.401 0.599
H30-H36 Disorders of choroid and retina
0.000 0.402 0.598
L42 Pityriasis rosea
0.000 0.402 0.598
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.403 0.597
Chapter XXII Codes for special purposes
0.000 0.404 0.596
G80 Infantile cerebral palsy
0.000 0.405 0.595
L85 Other epidermal thickening
0.000 0.406 0.594
E61 Deficiency of other nutrient elements
0.000 0.411 0.589
D74 Methaemoglobinaemia
0.000 0.411 0.589
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.411 0.589
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.411 0.589
M91-M94 Chondropathies
0.000 0.411 0.589
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.412 0.588
E45 Retarded development following protein-energy malnutrition
0.000 0.412 0.588
E43 Unspecified severe protein-energy malnutrition
0.000 0.412 0.588
E42 Marasmic kwashiorkor
0.000 0.412 0.588
E41 Nutritional marasmus
0.000 0.412 0.588
E40 Kwashiorkor
0.000 0.412 0.588
L43 Lichen planus
0.000 0.413 0.587
L50-L54 Urticaria and erythema
0.000 0.415 0.585
G81 Hemiplegia
0.000 0.415 0.585
M07.38 Other psoriatic arthropathies (Other)
0.000 0.416 0.584
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.416 0.584
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.416 0.584
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.416 0.584
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.416 0.584
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.416 0.584
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.416 0.584
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.416 0.584
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.416 0.584
G64 Other disorders of peripheral nervous system
0.000 0.417 0.583
H43.8 Other disorders of vitreous body
0.000 0.417 0.583
L81.4 Other melanin hyperpigmentation
0.000 0.417 0.583
E55 Vitamin D deficiency
0.000 0.418 0.581
G60 Hereditary and idiopathic neuropathy
0.000 0.420 0.580
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.421 0.579
E63 Other nutritional deficiencies
0.000 0.421 0.579
E56 Other vitamin deficiencies
0.000 0.421 0.579
E51 Thiamine deficiency
0.000 0.421 0.579
E50 Vitamin A deficiency
0.000 0.421 0.579
E60 Dietary zinc deficiency
0.000 0.421 0.579
E59 Dietary selenium deficiency
0.000 0.421 0.579
E58 Dietary calcium deficiency
0.000 0.421 0.579
E54 Ascorbic acid deficiency
0.000 0.421 0.579
E52 Niacin deficiency [pellagra]
0.000 0.421 0.579
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.422 0.578
H36 Retinal disorders in diseases classified elsewhere
0.000 0.422 0.578
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.425 0.575
H53.2 Diplopia
0.000 0.427 0.573
B34.8 Other viral infections of unspecified site
0.000 0.427 0.573
B34.4 Papovirus infection, unspecified
0.000 0.427 0.573
B34.3 Parvovirus infection, unspecified
0.000 0.427 0.573
B34.2 Coronavirus infection, unspecified
0.000 0.427 0.573
B34.1 Enterovirus infection, unspecified
0.000 0.427 0.573
B34.0 Adenovirus infection, unspecified
0.000 0.427 0.573
E04.2 Non-toxic multinodular goitre
0.000 0.428 0.572
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.428 0.572
D61.8 Other specified aplastic anaemias
0.000 0.428 0.572
D61.3 Idiopathic aplastic anaemia
0.000 0.428 0.572
D61.2 Aplastic anaemia due to other external agents
0.000 0.428 0.572
D61.1 Drug-induced aplastic anaemia
0.000 0.428 0.572
D61.0 Constitutional aplastic anaemia
0.000 0.428 0.572
G62.8 Other specified polyneuropathies
0.000 0.428 0.572
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.000 0.430 0.570
M80 Osteoporosis with pathological fracture
0.000 0.430 0.570
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.434 0.566
E11.1 With ketoacidosis
0.000 0.434 0.566
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.435 0.565
G70.0 Myasthenia gravis
0.000 0.436 0.564
G31.2 Degeneration of nervous system due to alcohol
0.000 0.436 0.564
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.436 0.564
G31.0 Circumscribed brain atrophy
0.000 0.436 0.564
H36.0 Diabetic retinopathy
0.000 0.437 0.563
H10-H13 Disorders of conjunctiva
0.000 0.437 0.563
L29 Pruritus
0.000 0.437 0.563
L83 Acanthosis nigricans
0.000 0.440 0.560
E53.8 Deficiency of other specified B group vitamins
0.000 0.443 0.557
B49 Unspecified mycosis
0.000 0.444 0.556
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.444 0.556
A08 Viral and other specified intestinal infections
0.000 0.444 0.556
L89 Decubitus ulcer
0.000 0.444 0.556
B35.3 Tinea pedis
0.000 0.446 0.554
A48 Other bacterial diseases, not elsewhere classified
0.000 0.447 0.552
A44 Bartonellosis
0.000 0.447 0.552
A43 Nocardiosis
0.000 0.447 0.552
A42 Actinomycosis
0.000 0.447 0.552
A39 Meningococcal infection
0.000 0.447 0.552
A37 Whooping cough
0.000 0.447 0.552
A36 Diphtheria
0.000 0.447 0.552
A32 Listeriosis
0.000 0.447 0.552
A31 Infection due to other mycobacteria
0.000 0.447 0.552
A30 Leprosy [Hansen's disease]
0.000 0.447 0.552
A38 Scarlet fever
0.000 0.447 0.552
A35 Other tetanus
0.000 0.447 0.552
A34 Obstetrical tetanus
0.000 0.447 0.552
A33 Tetanus neonatorum
0.000 0.447 0.552
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.448 0.552
E80.6 Other disorders of bilirubin metabolism
0.000 0.448 0.552
E80.5 Crigler-Najjar syndrome
0.000 0.448 0.552
E80.3 Defects of catalase and peroxydase
0.000 0.448 0.552
E80.2 Other porphyria
0.000 0.448 0.552
E80.1 Porphyria cutanea tarda
0.000 0.448 0.552
E80.0 Hereditary erythropoietic porphyria
0.000 0.448 0.552
M46 Other inflammatory spondylopathies
0.000 0.448 0.552
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.450 0.550
N50.0 Atrophy of testis
0.549 0.450 0.000
A41.9 Septicaemia, unspecified
0.000 0.451 0.549
A49 Bacterial infection of unspecified site
0.000 0.451 0.549
M11.2 Other chondrocalcinosis
0.000 0.451 0.549
L03 Cellulitis
0.000 0.454 0.546
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.454 0.546
E85 Amyloidosis
0.000 0.455 0.545
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.457 0.542
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.458 0.542
M95.0 Acquired deformity of nose
0.000 0.458 0.542
M86-M90 Other osteopathies
0.000 0.458 0.541
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.460 0.540
G62.2 Polyneuropathy due to other toxic agents
0.000 0.461 0.539
G62.1 Alcoholic polyneuropathy
0.000 0.461 0.539
G62.0 Drug-induced polyneuropathy
0.000 0.461 0.539
M65 Synovitis and tenosynovitis
0.000 0.462 0.538
G30.8 Other Alzheimer's disease
0.000 0.462 0.538
G30.1 Alzheimer's disease with late onset
0.000 0.462 0.538
G30.0 Alzheimer's disease with early onset
0.000 0.462 0.538
L91.8 Other hypertrophic disorders of skin
0.000 0.462 0.538
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.463 0.537
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.463 0.537
L05.0 Pilonidal cyst with abscess
0.000 0.464 0.536
G91 Hydrocephalus
0.000 0.465 0.535
G20-G26 Extrapyramidal and movement disorders
0.000 0.466 0.534
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.466 0.534
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.466 0.534
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.466 0.534
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.466 0.534
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.466 0.534
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.466 0.534
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.466 0.534
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.466 0.534
D73.0 Hyposplenism
0.000 0.467 0.533
E11.2 With renal complications
0.000 0.470 0.530
A40 Streptococcal septicaemia
0.000 0.470 0.530
E11.0 With coma
0.000 0.471 0.529
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.471 0.529
D75.1 Secondary polycythaemia
0.000 0.472 0.528
E11.8 With unspecified complications
0.000 0.473 0.527
E11.7 With multiple complications
0.000 0.473 0.527
L28 Lichen simplex chronicus and prurigo
0.000 0.473 0.526
H40 Glaucoma
0.000 0.474 0.526
M00 Pyogenic arthritis
0.000 0.474 0.525
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.476 0.524
L94 Other localised connective tissue disorders
0.000 0.476 0.524
L87 Transepidermal elimination disorders
0.000 0.476 0.524
L88 Pyoderma gangrenosum
0.000 0.476 0.524

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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