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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844580
log Bayes Factor = 180.244
Chromosome 6   position 31,333,303  (GRCh37) Explore rs2844580 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K51 Ulcerative colitis
0.000 0.001 0.999
K51.9 Ulcerative colitis, unspecified
0.000 0.001 0.999
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.997 0.003 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.993 0.007 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.009 0.991
E10.1 With ketoacidosis
0.986 0.014 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.979 0.021 0.000
K50-K52 Noninfective enteritis and colitis
0.000 0.023 0.977
L40.0 Psoriasis vulgaris
0.000 0.026 0.974
K50 Crohn's disease [regional enteritis]
0.000 0.029 0.971
K51.4 Pseudopolyposis of colon
0.000 0.036 0.964
E16 Other disorders of pancreatic internal secretion
0.964 0.036 0.000
E14.3 With ophthalmic complications
0.958 0.042 0.000
E20-E35 Disorders of other endocrine glands
0.952 0.048 0.000
M07.3 Other psoriatic arthropathies
0.000 0.049 0.951
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.051 0.949
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.053 0.947
E16.2 Hypoglycaemia, unspecified
0.942 0.058 0.000
E27 Other disorders of adrenal gland
0.938 0.062 0.000
K50.1 Crohn's disease of large intestine
0.000 0.064 0.936
K50.9 Crohn's disease, unspecified
0.000 0.066 0.934
E27.1 Primary adrenocortical insufficiency
0.928 0.072 0.000
J33.0 Polyp of nasal cavity
0.916 0.084 0.000
J33.9 Nasal polyp, unspecified
0.914 0.086 0.000
J33 Nasal polyp
0.913 0.087 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.125 0.875
E14.9 Without complications
0.864 0.136 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.144 0.856
M06.9 Rheumatoid arthritis, unspecified
0.851 0.149 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.848 0.152 0.000
E10.8 With unspecified complications
0.842 0.158 0.000
E16.1 Other hypoglycaemia
0.840 0.160 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.839 0.161 0.000
E14.6 With other specified complications
0.835 0.165 0.000
E10.2 With renal complications
0.834 0.166 0.000
K50.0 Crohn's disease of small intestine
0.000 0.166 0.834
E10.6 With other specified complications
0.830 0.170 0.000
M45 Ankylosing spondylitis
0.000 0.171 0.829
E14.2 Withrenal complications
0.828 0.172 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.823 0.177 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.817 0.183 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.813 0.187 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.188 0.812
K90 Intestinal malabsorption
0.811 0.189 0.000
E24 Cushing's syndrome
0.808 0.192 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.193 0.807
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.805 0.195 0.000
E07 Other disorders of thyroid
0.801 0.199 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.205 0.795
E14.1 With ketoacidosis
0.792 0.208 0.000
E23 Hypofunction and other disorders of pituitary gland
0.791 0.209 0.000
J33.8 Other polyp of sinus
0.791 0.209 0.000
E10.0 With coma
0.784 0.216 0.000
L40.8 Other psoriasis
0.000 0.220 0.780
G35 Multiple sclerosis
0.000 0.220 0.780
E13 Other specified diabetes mellitus
0.778 0.222 0.000
L40.4 Guttate psoriasis
0.000 0.231 0.769
K90.9 Intestinal malabsorption, unspecified
0.766 0.234 0.000
L40.1 Generalised pustular psoriasis
0.000 0.235 0.765
E14.5 With peripheral circulatory complications
0.765 0.235 0.000
E14.0 With coma
0.758 0.242 0.000
K51.8 Other ulcerative colitis
0.000 0.245 0.755
J45 Asthma
0.754 0.246 0.000
E23.2 Diabetes insipidus
0.753 0.247 0.000
K52 Other non-infective gastro-enteritis and colitis
0.000 0.252 0.748
E05.8 Other thyrotoxicosis
0.746 0.254 0.000
E03.8 Other specified hypothyroidism
0.745 0.255 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.743 0.257 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.276 0.724
E31 Polyglandular dysfunction
0.723 0.276 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.723 0.276 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.277 0.723
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E27.9 Disorder of adrenal gland, unspecified
0.712 0.288 0.000
E14.7 With multiple complications
0.712 0.288 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.711 0.289 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.705 0.295 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.295 0.705
K51.5 Mucosal proctocolitis
0.000 0.296 0.704
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.704 0.296 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.703 0.297 0.000
E15 Nondiabetic hypoglycaemic coma
0.702 0.298 0.000
E03.1 Congenital hypothyroidism without goitre
0.696 0.303 0.000
E25 Adrenogenital disorders
0.695 0.305 0.000
K52.3 Indeterminate colitis
0.000 0.305 0.695
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.306 0.694
E83 Disorders of mineral metabolism
0.000 0.308 0.692
E16.9 Disorder of pancreatic internal secretion, unspecified
0.691 0.309 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.691 0.309 0.000
E16.4 Abnormal secretion of gastrin
0.691 0.309 0.000
E16.3 Increased secretion of glucagon
0.691 0.309 0.000
E28 Ovarian dysfunction
0.690 0.310 0.000
E10.7 With multiple complications
0.688 0.312 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.683 0.317 0.000
E32 Diseases of thymus
0.683 0.317 0.000
E30 Disorders of puberty, not elsewhere classified
0.683 0.317 0.000
J45.0 Predominantly allergic asthma
0.683 0.317 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.318 0.682
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.318 0.682
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.318 0.682
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.318 0.682
E22 Hyperfunction of pituitary gland
0.680 0.320 0.000
E29 Testicular dysfunction
0.678 0.322 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.327 0.673
E27.5 Adrenomedullary hyperfunction
0.672 0.327 0.000
E27.0 Other adrenocortical overactivity
0.672 0.327 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.668 0.332 0.000
E24.0 Pituitary-dependent Cushing's disease
0.667 0.333 0.000
E07.8 Other specified disorders of thyroid
0.664 0.336 0.000
K52.1 Toxic gastro-enteritis and colitis
0.000 0.342 0.658
E10.4 With neurological complications
0.656 0.344 0.000
E24.2 Drug-induced Cushing's syndrome
0.652 0.348 0.000
J33.1 Polypoid sinus degeneration
0.650 0.350 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.642 0.358 0.000
E10.5 With peripheral circulatory complications
0.637 0.363 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.636 0.364 0.000
E40-E46 Malnutrition
0.634 0.366 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.368 0.632
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.368 0.632
E13.9 Without complications
0.630 0.370 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.626 0.374 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.377 0.623
E14.4 With neurological complications
0.616 0.384 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.386 0.614
E34 Other endocrine disorders
0.598 0.402 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.405 0.595
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.405 0.595
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.405 0.595
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.405 0.595
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.405 0.595
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.405 0.595
E24.9 Cushing's syndrome, unspecified
0.587 0.413 0.000
E20 Hypoparathyroidism
0.586 0.414 0.000
G36 Other acute disseminated demyelination
0.000 0.415 0.584
K90.3 Pancreatic steatorrhoea
0.581 0.418 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.581 0.418 0.000
K90.1 Tropical sprue
0.581 0.418 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.580 0.420 0.000
E24.3 Ectopic ACTH syndrome
0.580 0.420 0.000
E24.1 Nelson's syndrome
0.580 0.420 0.000
J45.1 Nonallergic asthma
0.576 0.424 0.000
E07.1 Dyshormogenetic goitre
0.574 0.426 0.000
E07.0 Hypersecretion of calcitonin
0.574 0.426 0.000
E14.8 With unspecified complications
0.572 0.427 0.000
J45.8 Mixed asthma
0.572 0.428 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.429 0.571
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.571 0.429 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.567 0.433 0.000
E23.1 Drug-induced hypopituitarism
0.567 0.433 0.000
E07.9 Disorder of thyroid, unspecified
0.564 0.436 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.562 0.438 0.000
E31.0 Autoimmune polyglandular failure
0.559 0.441 0.000
E13.8 With unspecified complications
0.558 0.442 0.000
E13.7 With multiple complications
0.558 0.442 0.000
E13.6 With other specified complications
0.558 0.442 0.000
E13.5 With peripheral circulatory complications
0.558 0.442 0.000
E13.4 With neurological complications
0.558 0.442 0.000
E13.2 With renal complications
0.558 0.442 0.000
E13.1 With ketoacidosis
0.558 0.442 0.000
E13.0 With coma
0.558 0.442 0.000
E24.8 Other Cushing's syndrome
0.556 0.444 0.000
E13.3 With ophthalmic complications
0.542 0.458 0.000
E23.6 Other disorders of pituitary gland
0.542 0.458 0.000
E29.9 Testicular dysfunction, unspecified
0.538 0.461 0.000
E27.8 Other specified disorders of adrenal gland
0.538 0.462 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.536 0.463 0.000
K90.8 Other intestinal malabsorption
0.529 0.471 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.477 0.523
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.481 0.519
E31.9 Polyglandular dysfunction, unspecified
0.519 0.481 0.000
E31.8 Other polyglandular dysfunction
0.519 0.481 0.000
E31.1 Polyglandular hyperfunction
0.519 0.481 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.481 0.519
K50.8 Other Crohn's disease
0.000 0.484 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.510 0.490 0.000
E28.2 Polycystic ovarian syndrome
0.507 0.493 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.495 0.505
G37.4 Subacute necrotising myelitis
0.000 0.495 0.505
G37.2 Central pontine myelinolysis
0.000 0.495 0.505
G37.1 Central demyelination of corpus callosum
0.000 0.495 0.505
G37.0 Diffuse sclerosis
0.000 0.495 0.505
E22.9 Hyperfunction of pituitary gland, unspecified
0.501 0.498 0.000
E25.9 Adrenogenital disorder, unspecified
0.498 0.502 0.000
E25.8 Other adrenogenital disorders
0.498 0.502 0.000
E83.8 Other disorders of mineral metabolism
0.000 0.504 0.496
E83.2 Disorders of zinc metabolism
0.000 0.504 0.496
E83.0 Disorders of copper metabolism
0.000 0.504 0.496
E23.7 Disorder of pituitary gland, unspecified
0.495 0.505 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.505 0.495
E28.9 Ovarian dysfunction, unspecified
0.495 0.505 0.000
E28.8 Other ovarian dysfunction
0.495 0.505 0.000
E28.1 Androgen excess
0.495 0.505 0.000
E28.0 Oestrogen excess
0.495 0.505 0.000
E26 Hyperaldosteronism
0.494 0.506 0.000
E30.9 Disorder of puberty, unspecified
0.490 0.510 0.000
E30.8 Other disorders of puberty
0.490 0.510 0.000
E30.1 Precocious puberty
0.490 0.510 0.000
E30.0 Delayed puberty
0.490 0.510 0.000
E32.9 Disease of thymus, unspecified
0.490 0.510 0.000
E32.8 Other diseases of thymus
0.490 0.510 0.000
E32.1 Abscess of thymus
0.490 0.510 0.000
E32.0 Persistent hyperplasia of thymus
0.490 0.510 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.490 0.510 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.490 0.510 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.490 0.510 0.000
E28.3 Primary ovarian failure
0.489 0.511 0.000
E22.8 Other hyperfunction of pituitary gland
0.488 0.512 0.000
E29.8 Other testicular dysfunction
0.486 0.514 0.000
E29.0 Testicular hyperfunction
0.486 0.514 0.000
G36.0 Neuromyelitis optica [Devic]
0.000 0.515 0.484
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.516 0.483
M07 Psoriatic and enteropathic arthropathies
0.046 0.530 0.424
E22.1 Hyperprolactinaemia
0.465 0.535 0.000
E34.9 Endocrine disorder, unspecified
0.465 0.535 0.000
E27.2 Addisonian crisis
0.464 0.535 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.454 0.545 0.000
E45 Retarded development following protein-energy malnutrition
0.454 0.545 0.000
E43 Unspecified severe protein-energy malnutrition
0.454 0.545 0.000
E42 Marasmic kwashiorkor
0.454 0.545 0.000
E41 Nutritional marasmus
0.454 0.545 0.000
E40 Kwashiorkor
0.454 0.545 0.000
E83.5 Disorders of calcium metabolism
0.000 0.551 0.449
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.555 0.445
E34.3 Short stature, not elsewhere classified
0.445 0.555 0.000
E06 Thyroiditis
0.442 0.558 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.435 0.564 0.000
E34.5 Androgen resistance syndrome
0.429 0.571 0.000
E34.4 Constitutional tall stature
0.429 0.571 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.429 0.571 0.000
E34.1 Other hypersecretion of intestinal hormones
0.429 0.571 0.000
E34.8 Other specified endocrine disorders
0.421 0.579 0.000
E20.8 Other hypoparathyroidism
0.420 0.580 0.000
E20.1 Pseudohypoparathyroidism
0.420 0.580 0.000
E20.0 Idiopathic hypoparathyroidism
0.420 0.580 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.581 0.419
G36.8 Other specified acute disseminated demyelination
0.000 0.581 0.419
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.581 0.419
E29.1 Testicular hypofunction
0.407 0.593 0.000
E46 Unspecified protein-energy malnutrition
0.371 0.629 0.000
E50-E64 Other nutritional deficiencies
0.360 0.640 0.000
M06 Other rheumatoid arthritis
0.342 0.640 0.018
E26.8 Other hyperaldosteronism
0.354 0.646 0.000
E26.1 Secondary hyperaldosteronism
0.354 0.646 0.000
E22.0 Acromegaly and pituitary gigantism
0.348 0.652 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.343 0.656 0.001
L40-L45 Papulosquamous disorders
0.000 0.659 0.341
M07.6 Other enteropathic arthropathies
0.032 0.662 0.306
M07.5 Arthropathy in ulcerative colitis
0.033 0.663 0.304
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.033 0.663 0.304
M07.2 Psoriatic spondylitis
0.033 0.663 0.304
M07.1 Arthritis mutilans
0.033 0.663 0.304
M07.0 Distal interphalangeal psoriatic arthropathy
0.033 0.663 0.304
E26.9 Hyperaldosteronism, unspecified
0.330 0.670 0.000
E23.0 Hypopituitarism
0.329 0.670 0.000
E44.1 Mild protein-energy malnutrition
0.326 0.674 0.000
E44.0 Moderate protein-energy malnutrition
0.326 0.674 0.000
E20.9 Hypoparathyroidism, unspecified
0.323 0.677 0.000
E06.4 Drug-induced thyroiditis
0.317 0.683 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.317 0.683 0.000
E06.1 Subacute thyroiditis
0.317 0.683 0.000
E06.0 Acute thyroiditis
0.317 0.683 0.000
M06.3 Rheumatoid nodule
0.306 0.688 0.007
E06.5 Other chronic thyroiditis
0.307 0.692 0.000
M06.34 Rheumatoid nodule (Hand)
0.277 0.720 0.002
E63 Other nutritional deficiencies
0.271 0.729 0.000
E58 Dietary calcium deficiency
0.264 0.736 0.000
E34.0 Carcinoid syndrome
0.259 0.741 0.001
E06.3 Autoimmune thyroiditis
0.258 0.741 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.258 0.741 0.000
E56 Other vitamin deficiencies
0.258 0.741 0.000
E50 Vitamin A deficiency
0.258 0.741 0.000
E60 Dietary zinc deficiency
0.258 0.741 0.000
E59 Dietary selenium deficiency
0.258 0.741 0.000
E52 Niacin deficiency [pellagra]
0.258 0.741 0.000
M06.2 Rheumatoid bursitis
0.246 0.741 0.013
M06.1 Adult-onset Still's disease
0.246 0.741 0.013
E54 Ascorbic acid deficiency
0.258 0.742 0.000
E51 Thiamine deficiency
0.256 0.744 0.000
L41 Parapsoriasis
0.000 0.756 0.244
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.756 0.244
E65-E68 Obesity and other hyperalimentation
0.243 0.756 0.002
M07.69 Other enteropathic arthropathies (Site unspecified)
0.022 0.757 0.221
M07.68 Other enteropathic arthropathies (Other)
0.023 0.757 0.219
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.023 0.757 0.219
M07.66 Other enteropathic arthropathies (Lower leg)
0.023 0.757 0.219
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.023 0.757 0.219
M07.64 Other enteropathic arthropathies (Hand)
0.023 0.757 0.219
M07.63 Other enteropathic arthropathies (Forearm)
0.023 0.757 0.219
M07.62 Other enteropathic arthropathies (Upper arm)
0.023 0.757 0.219
M07.61 Other enteropathic arthropathies (Shoulder region)
0.023 0.757 0.219
M07.60 Other enteropathic arthropathies (Multiple sites)
0.023 0.757 0.219
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.024 0.758 0.218
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.024 0.758 0.218
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.024 0.758 0.218
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.024 0.758 0.218
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.024 0.758 0.218
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.024 0.758 0.218
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.024 0.758 0.218
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.024 0.758 0.218
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.024 0.758 0.218
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.024 0.758 0.218
M07.19 Arthritis mutilans (Site unspecified)
0.024 0.758 0.218
M07.18 Arthritis mutilans (Other)
0.024 0.758 0.218
M07.17 Arthritis mutilans (Ankle and foot)
0.024 0.758 0.218
M07.16 Arthritis mutilans (Lower leg)
0.024 0.758 0.218
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.024 0.758 0.218
M07.14 Arthritis mutilans (Hand)
0.024 0.758 0.218
M07.13 Arthritis mutilans (Forearm)
0.024 0.758 0.218
M07.12 Arthritis mutilans (Upper arm)
0.024 0.758 0.218
M07.11 Arthritis mutilans (Shoulder region)
0.024 0.758 0.218
M07.10 Arthritis mutilans (Multiple sites)
0.024 0.758 0.218
M07.29 Psoriatic spondylitis (Site unspecified)
0.024 0.758 0.218
M07.28 Psoriatic spondylitis (Other)
0.024 0.758 0.218
M07.27 Psoriatic spondylitis (Ankle and foot)
0.024 0.758 0.218
M07.26 Psoriatic spondylitis (Lower leg)
0.024 0.758 0.218
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.024 0.758 0.218
M07.24 Psoriatic spondylitis (Hand)
0.024 0.758 0.218
M07.23 Psoriatic spondylitis (Forearm)
0.024 0.758 0.218
M07.22 Psoriatic spondylitis (Upper arm)
0.024 0.758 0.218
M07.21 Psoriatic spondylitis (Shoulder region)
0.024 0.758 0.218
M07.20 Psoriatic spondylitis (Multiple sites)
0.024 0.758 0.218
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.024 0.758 0.218
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.024 0.758 0.218
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.024 0.758 0.218
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.024 0.758 0.218
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.024 0.758 0.218
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.024 0.758 0.218
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.024 0.758 0.218
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.024 0.758 0.218
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.024 0.758 0.218
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.024 0.758 0.218
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.024 0.758 0.218
M07.58 Arthropathy in ulcerative colitis (Other)
0.024 0.758 0.218
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.024 0.758 0.218
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.024 0.758 0.218
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.024 0.758 0.218
M07.54 Arthropathy in ulcerative colitis (Hand)
0.024 0.758 0.218
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.024 0.758 0.218
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.024 0.758 0.218
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.024 0.758 0.218
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.024 0.758 0.218
L44 Other papulosquamous disorders
0.000 0.759 0.241
M06.32 Rheumatoid nodule (Upper arm)
0.234 0.762 0.004
M06.4 Inflammatory polyarthropathy
0.227 0.763 0.011
M81.9 Osteoporosis, unspecified
0.236 0.764 0.000
M06.8 Other specified rheumatoid arthritis
0.218 0.768 0.014
M81.90 Osteoporosis, unspecified (Multiple sites)
0.229 0.771 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.223 0.773 0.005
M81.99 Osteoporosis, unspecified (Site unspecified)
0.226 0.774 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.219 0.776 0.005
M06.38 Rheumatoid nodule (Other)
0.219 0.776 0.005
M06.36 Rheumatoid nodule (Lower leg)
0.219 0.776 0.005
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.219 0.776 0.005
M06.33 Rheumatoid nodule (Forearm)
0.219 0.776 0.005
M06.31 Rheumatoid nodule (Shoulder region)
0.219 0.776 0.005
M81.98 Osteoporosis, unspecified (Other)
0.223 0.777 0.000
E26.0 Primary hyperaldosteronism
0.213 0.786 0.001
M06.37 Rheumatoid nodule (Ankle and foot)
0.205 0.790 0.005
L42 Pityriasis rosea
0.000 0.790 0.210
E63.9 Nutritional deficiency, unspecified
0.207 0.793 0.000
E61 Deficiency of other nutrient elements
0.206 0.794 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.804 0.196
M81.93 Osteoporosis, unspecified (Forearm)
0.196 0.804 0.000
E63.8 Other specified nutritional deficiencies
0.194 0.805 0.000
E63.1 Imbalance of constituents of food intake
0.194 0.805 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.194 0.805 0.000
E06.9 Thyroiditis, unspecified
0.187 0.813 0.001
E50.9 Vitamin A deficiency, unspecified
0.185 0.814 0.000
E50.8 Other manifestations of vitamin A deficiency
0.185 0.814 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.185 0.814 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.185 0.814 0.000
E50.5 Vitamin A deficiency with night blindness
0.185 0.814 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.185 0.814 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.185 0.814 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.185 0.814 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.185 0.814 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.185 0.814 0.000
E56.9 Vitamin deficiency, unspecified
0.185 0.814 0.000
E56.8 Deficiency of other vitamins
0.185 0.814 0.000
E56.1 Deficiency of vitamin K
0.185 0.814 0.000
E56.0 Deficiency of vitamin E
0.185 0.814 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.185 0.814 0.000
E64.8 Sequelae of other nutritional deficiencies
0.185 0.814 0.000
E64.3 Sequelae of rickets
0.185 0.814 0.000
E64.2 Sequelae of vitamin C deficiency
0.185 0.814 0.000
E64.1 Sequelae of vitamin A deficiency
0.185 0.814 0.000
E64.0 Sequelae of protein-energy malnutrition
0.185 0.814 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.176 0.814 0.009
M06.18 Adult-onset Still's disease (Other)
0.176 0.814 0.009
M06.17 Adult-onset Still's disease (Ankle and foot)
0.176 0.814 0.009
M06.16 Adult-onset Still's disease (Lower leg)
0.176 0.814 0.009
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.176 0.814 0.009
M06.14 Adult-onset Still's disease (Hand)
0.176 0.814 0.009
M06.13 Adult-onset Still's disease (Forearm)
0.176 0.814 0.009
M06.12 Adult-onset Still's disease (Upper arm)
0.176 0.814 0.009
M06.11 Adult-onset Still's disease (Shoulder region)
0.176 0.814 0.009
M06.10 Adult-onset Still's disease (Multiple sites)
0.176 0.814 0.009
M06.29 Rheumatoid bursitis (Site unspecified)
0.176 0.814 0.009
M06.28 Rheumatoid bursitis (Other)
0.176 0.814 0.009
M06.27 Rheumatoid bursitis (Ankle and foot)
0.176 0.814 0.009
M06.26 Rheumatoid bursitis (Lower leg)
0.176 0.814 0.009
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.176 0.814 0.009
M06.24 Rheumatoid bursitis (Hand)
0.176 0.814 0.009
M06.23 Rheumatoid bursitis (Forearm)
0.176 0.814 0.009
M06.22 Rheumatoid bursitis (Upper arm)
0.176 0.814 0.009
M06.21 Rheumatoid bursitis (Shoulder region)
0.176 0.814 0.009
M06.20 Rheumatoid bursitis (Multiple sites)
0.176 0.814 0.009
N85.8 Other specified noninflammatory disorders of uterus
0.000 0.814 0.186
E51.9 Thiamine deficiency, unspecified
0.183 0.816 0.000
E51.8 Other manifestations of thiamine deficiency
0.183 0.816 0.000
E51.1 Beriberi
0.183 0.816 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.183 0.817 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.175 0.818 0.007
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.819 0.181
E51.2 Wernicke's encephalopathy
0.180 0.819 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.180 0.820 0.000
M81 Osteoporosis without pathological fracture
0.178 0.822 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.177 0.823 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.825 0.175
L41.8 Other parapsoriasis
0.000 0.825 0.175
L41.5 Retiform parapsoriasis
0.000 0.825 0.175
L41.4 Large plaque parapsoriasis
0.000 0.825 0.175
L41.3 Small plaque parapsoriasis
0.000 0.825 0.175
L41.2 Lymphomatoid papulosis
0.000 0.825 0.175
L41.1 Pityriasis lichenoides chronica
0.000 0.825 0.175
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.825 0.175
E55 Vitamin D deficiency
0.175 0.825 0.000
E67 Other hyperalimentation
0.174 0.825 0.001
E68 Sequelae of hyperalimentation
0.174 0.825 0.001
L44.9 Papulosquamous disorder, unspecified
0.000 0.827 0.173
L44.8 Other specified papulosquamous disorders
0.000 0.827 0.173
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.827 0.173
L44.3 Lichen ruber moniliformis
0.000 0.827 0.173
L44.2 Lichen striatus
0.000 0.827 0.173
L44.1 Lichen nitidus
0.000 0.827 0.173
M06.48 Inflammatory polyarthropathy (Other)
0.163 0.830 0.008
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.163 0.830 0.008
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.163 0.830 0.008
M06.44 Inflammatory polyarthropathy (Hand)
0.163 0.830 0.008
M06.43 Inflammatory polyarthropathy (Forearm)
0.163 0.830 0.008
M06.42 Inflammatory polyarthropathy (Upper arm)
0.163 0.830 0.008
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.163 0.830 0.008
L44.0 Pityriasis rubra pilaris
0.000 0.830 0.170
M81.94 Osteoporosis, unspecified (Hand)
0.169 0.830 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.169 0.831 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.832 0.168
L43 Lichen planus
0.000 0.833 0.167
M06.88 Other specified rheumatoid arthritis (Other)
0.157 0.833 0.010
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.157 0.833 0.010
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.157 0.833 0.010
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.157 0.833 0.010
M06.84 Other specified rheumatoid arthritis (Hand)
0.157 0.833 0.010
M06.83 Other specified rheumatoid arthritis (Forearm)
0.157 0.833 0.010
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.157 0.833 0.010
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.157 0.833 0.010
E53 Deficiency of other B group vitamins
0.166 0.834 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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