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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844701
log Bayes Factor = 36.6997
Chromosome 6   position 30,912,691  (GRCh37) Explore rs2844701 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
E11.9 Without complications
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.003 0.997
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.005 0.995
E14 Unspecified diabetes mellitus
0.000 0.010 0.990
E78.5 Hyperlipidaemia, unspecified
0.000 0.024 0.976
E14.9 Without complications
0.000 0.026 0.974
G35-G37 Demyelinating diseases of the central nervous system
0.944 0.056 0.000
K90.0 Coeliac disease
0.000 0.064 0.936
E11.5 With peripheral circulatory complications
0.000 0.074 0.926
E10.1 With ketoacidosis
0.000 0.077 0.923
E78.2 Mixed hyperlipidaemia
0.000 0.087 0.913
E10.4 With neurological complications
0.000 0.087 0.913
L40.0 Psoriasis vulgaris
0.000 0.099 0.901
G37 Other demyelinating diseases of central nervous system
0.896 0.104 0.000
E10.2 With renal complications
0.000 0.124 0.876
E70-E90 Metabolic disorders
0.005 0.125 0.870
E11.6 With other specified complications
0.000 0.128 0.872
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.128 0.872
E14.3 With ophthalmic complications
0.000 0.137 0.863
E11.4 With neurological complications
0.000 0.146 0.854
G37.9 Demyelinating disease of central nervous system, unspecified
0.849 0.151 0.000
E13 Other specified diabetes mellitus
0.000 0.165 0.835
E11.1 With ketoacidosis
0.000 0.179 0.821
E11.0 With coma
0.000 0.195 0.805
E10.5 With peripheral circulatory complications
0.000 0.208 0.792
E78.1 Pure hyperglyceridaemia
0.000 0.214 0.786
E10.0 With coma
0.000 0.222 0.778
E11.2 With renal complications
0.000 0.231 0.769
E78.8 Other disorders of lipoprotein metabolism
0.000 0.234 0.766
E10.6 With other specified complications
0.000 0.247 0.753
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.258 0.742
E10.8 With unspecified complications
0.000 0.258 0.742
G37.8 Other specified demyelinating diseases of central nervous system
0.741 0.259 0.000
L40.8 Other psoriasis
0.000 0.276 0.724
Chapter VI Diseases of the nervous system
0.723 0.277 0.000
E85 Amyloidosis
0.003 0.279 0.718
E13.9 Without complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
E78.6 Lipoprotein deficiency
0.000 0.287 0.713
E78.3 Hyperchylomicronaemia
0.000 0.287 0.713
E14.8 With unspecified complications
0.000 0.290 0.710
E14.7 With multiple complications
0.000 0.290 0.710
E14.6 With other specified complications
0.000 0.290 0.710
E14.5 With peripheral circulatory complications
0.000 0.290 0.710
E14.4 With neurological complications
0.000 0.290 0.710
E14.2 Withrenal complications
0.000 0.290 0.710
E14.1 With ketoacidosis
0.000 0.290 0.710
E14.0 With coma
0.000 0.290 0.710
G00-G09 Inflammatory diseases of the central nervous system
0.678 0.322 0.000
G36 Other acute disseminated demyelination
0.677 0.323 0.000
E78.4 Other hyperlipidaemia
0.000 0.332 0.668
G20-G26 Extrapyramidal and movement disorders
0.663 0.337 0.000
G30-G32 Other degenerative diseases of the nervous system
0.653 0.347 0.000
E74 Other disorders of carbohydrate metabolism
0.004 0.349 0.648
E16 Other disorders of pancreatic internal secretion
0.000 0.350 0.649
G37.5 Concentric sclerosis [Balo]
0.643 0.357 0.000
G37.4 Subacute necrotising myelitis
0.643 0.357 0.000
G37.2 Central pontine myelinolysis
0.643 0.357 0.000
G37.1 Central demyelination of corpus callosum
0.643 0.357 0.000
G37.0 Diffuse sclerosis
0.643 0.357 0.000
E79 Disorders of purine and pyrimidine metabolism
0.004 0.372 0.624
E77 Disorders of glycoprotein metabolism
0.004 0.372 0.624
E76 Disorders of glycosaminoglycan metabolism
0.004 0.372 0.624
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.004 0.372 0.624
E72 Other disorders of amino-acid metabolism
0.004 0.372 0.624
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.004 0.372 0.624
E70 Disorders of aromatic amino-acid metabolism
0.004 0.372 0.624
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.004 0.372 0.624
G40-G47 Episodic and paroxysmal disorders
0.623 0.377 0.000
E83 Disorders of mineral metabolism
0.467 0.379 0.154
G20 Parkinson's disease
0.609 0.391 0.000
E85.9 Amyloidosis, unspecified
0.002 0.392 0.606
E11.8 With unspecified complications
0.000 0.394 0.606
M06.9 Rheumatoid arthritis, unspecified
0.000 0.395 0.605
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.400 0.600
E13.8 With unspecified complications
0.000 0.401 0.599
E13.7 With multiple complications
0.000 0.401 0.599
E13.6 With other specified complications
0.000 0.401 0.599
E13.5 With peripheral circulatory complications
0.000 0.401 0.599
E13.4 With neurological complications
0.000 0.401 0.599
E13.3 With ophthalmic complications
0.000 0.401 0.599
E13.2 With renal complications
0.000 0.401 0.599
E13.1 With ketoacidosis
0.000 0.401 0.599
E13.0 With coma
0.000 0.401 0.599
E40-E46 Malnutrition
0.000 0.401 0.599
L40.3 Pustulosis palmaris et plantaris
0.000 0.402 0.598
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.594 0.406 0.000
E73 Lactose intolerance
0.004 0.406 0.590
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.004 0.412 0.584
E20-E35 Disorders of other endocrine glands
0.000 0.412 0.588
L40-L45 Papulosquamous disorders
0.000 0.414 0.586
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.584 0.416 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.417 0.583
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.570 0.430 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.431 0.569
E84 Cystic fibrosis
0.004 0.431 0.564
G06 Intracranial and intraspinal abscess and granuloma
0.566 0.434 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.565 0.435 0.000
G03 Meningitis due to other and unspecified causes
0.564 0.436 0.000
G40 Epilepsy
0.560 0.440 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.555 0.445 0.000
G43 Migraine
0.550 0.450 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.549 0.451 0.000
G24 Dystonia
0.547 0.453 0.000
G70-G73 Diseases of myoneural junction and muscle
0.546 0.454 0.000
E89.3 Postprocedural hypopituitarism
0.001 0.455 0.543
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.464 0.536
E15 Nondiabetic hypoglycaemic coma
0.000 0.468 0.532
E85.4 Organ-limited amyloidosis
0.002 0.476 0.522
G80-G83 Cerebral palsy and other paralytic syndromes
0.520 0.480 0.000
E24 Cushing's syndrome
0.000 0.480 0.520
E85.8 Other amyloidosis
0.002 0.483 0.515
E85.3 Secondary systemic amyloidosis
0.002 0.483 0.515
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.483 0.515
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.483 0.515
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.483 0.515
G30 Alzheimer's disease
0.517 0.483 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
L43 Lichen planus
0.000 0.486 0.514
E50-E64 Other nutritional deficiencies
0.000 0.495 0.505
M06 Other rheumatoid arthritis
0.000 0.497 0.503
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.502 0.498
G04 Encephalitis, myelitis and encephalomyelitis
0.496 0.504 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.504 0.495
K90 Intestinal malabsorption
0.000 0.507 0.493
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.493 0.507 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.492 0.508 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.002 0.509 0.488
G46.7 Other lacunar syndromes
0.490 0.510 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.486 0.514 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.486 0.514 0.000
G36.9 Acute disseminated demyelination, unspecified
0.485 0.514 0.000
G36.8 Other specified acute disseminated demyelination
0.485 0.514 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.485 0.514 0.000
G36.0 Neuromyelitis optica [Devic]
0.485 0.514 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.482 0.518 0.000
G03.9 Meningitis, unspecified
0.482 0.518 0.000
G31.2 Degeneration of nervous system due to alcohol
0.480 0.520 0.000
E22 Hyperfunction of pituitary gland
0.000 0.520 0.480
G43.9 Migraine, unspecified
0.479 0.521 0.000
G00 Bacterial meningitis, not elsewhere classified
0.478 0.522 0.000
G46.4 Cerebellar stroke syndrome
0.476 0.524 0.000
G23 Other degenerative diseases of basal ganglia
0.476 0.524 0.000
G21 Secondary Parkinsonism
0.476 0.524 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.476 0.524 0.000
G22 Parkinsonism in diseases classified elsewhere
0.476 0.524 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.526 0.473
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.473 0.527 0.000
L43.9 Lichen planus, unspecified
0.000 0.528 0.472
E24.9 Cushing's syndrome, unspecified
0.000 0.529 0.471
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.470 0.529 0.000
G24.9 Dystonia, unspecified
0.470 0.530 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.530 0.469
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.468 0.532 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.003 0.533 0.464
E74.8 Other specified disorders of carbohydrate metabolism
0.003 0.533 0.464
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.003 0.533 0.464
E74.2 Disorders of galactose metabolism
0.003 0.533 0.464
E74.1 Disorders of fructose metabolism
0.003 0.533 0.464
E74.0 Glycogen storage disease
0.003 0.533 0.464
G06.1 Intraspinal abscess and granuloma
0.467 0.533 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.534 0.466
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.534 0.466
E16.4 Abnormal secretion of gastrin
0.000 0.534 0.466
E16.3 Increased secretion of glucagon
0.000 0.534 0.466
E16.1 Other hypoglycaemia
0.000 0.534 0.466
E29 Testicular dysfunction
0.000 0.535 0.465
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.464 0.536 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.539 0.461
E23 Hypofunction and other disorders of pituitary gland
0.000 0.540 0.460
E11.3 With ophthalmic complications
0.000 0.540 0.460
M05-M14 Inflammatory polyarthropathies
0.000 0.541 0.459
G43.8 Other migraine
0.450 0.550 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.003 0.550 0.447
E70.8 Other disorders of aromatic amino-acid metabolism
0.003 0.550 0.447
E70.3 Albinism
0.003 0.550 0.447
E70.2 Disorders of tyrosine metabolism
0.003 0.550 0.447
E70.1 Other hyperphenylalaninaemias
0.003 0.550 0.447
E70.0 Classical phenylketonuria
0.003 0.550 0.447
E71.3 Disorders of fatty-acid metabolism
0.003 0.550 0.447
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.003 0.550 0.447
E71.1 Other disorders of branched-chain amino-acid metabolism
0.003 0.550 0.447
E71.0 Maple-syrup-urine disease
0.003 0.550 0.447
E72.9 Disorder of amino-acid metabolism, unspecified
0.003 0.550 0.447
E72.8 Other specified disorders of amino-acid metabolism
0.003 0.550 0.447
E72.5 Disorders of glycine metabolism
0.003 0.550 0.447
E72.4 Disorders of ornithine metabolism
0.003 0.550 0.447
E72.3 Disorders of lysine and hydroxylysine metabolism
0.003 0.550 0.447
E72.2 Disorders of urea cycle metabolism
0.003 0.550 0.447
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.003 0.550 0.447
E72.0 Disorders of amino-acid transport
0.003 0.550 0.447
E75.6 Lipid storage disorder, unspecified
0.003 0.550 0.447
E75.5 Other lipid storage disorders
0.003 0.550 0.447
E75.4 Neuronal ceroid lipofuscinosis
0.003 0.550 0.447
E75.3 Sphingolipidosis, unspecified
0.003 0.550 0.447
E75.2 Other sphingolipidosis
0.003 0.550 0.447
E75.1 Other gangliosidosis
0.003 0.550 0.447
E75.0 GM2 gangliosidosis
0.003 0.550 0.447
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.003 0.550 0.447
E76.8 Other disorders of glucosaminoglycan metabolism
0.003 0.550 0.447
E76.3 Mucopolysaccharidosis, unspecified
0.003 0.550 0.447
E76.2 Other mucopolysaccharidoses
0.003 0.550 0.447
E76.1 Mucopolysaccharidosis, type II
0.003 0.550 0.447
E76.0 Mucopolysaccharidosis, type I
0.003 0.550 0.447
E77.9 Disorder of glycoprotein metabolism, unspecified
0.003 0.550 0.447
E77.8 Other disorders of glycoprotein metabolism
0.003 0.550 0.447
E77.1 Defects in glycoprotein degradation
0.003 0.550 0.447
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.003 0.550 0.447
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.003 0.550 0.447
E79.8 Other disorders of purine and pyrimidine metabolism
0.003 0.550 0.447
E79.1 Lesch-Nyhan syndrome
0.003 0.550 0.447
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.003 0.550 0.447
G30.8 Other Alzheimer's disease
0.446 0.554 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.335 0.555 0.111
E83.8 Other disorders of mineral metabolism
0.335 0.555 0.111
E83.2 Disorders of zinc metabolism
0.335 0.555 0.111
E83.0 Disorders of copper metabolism
0.335 0.555 0.111
G83 Other paralytic syndromes
0.444 0.556 0.000
G70 Myasthenia gravis and other myoneural disorders
0.443 0.557 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.004 0.557 0.439
M07 Psoriatic and enteropathic arthropathies
0.000 0.558 0.442
G44 Other headache syndromes
0.440 0.560 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.561 0.439
G40.7 Petit mal, unspecified, without grand mal seizures
0.434 0.566 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.566 0.434
G41 Status epilepticus
0.433 0.567 0.000
G24.8 Other dystonia
0.432 0.568 0.000
M07.3 Other psoriatic arthropathies
0.000 0.570 0.430
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.570 0.429
E45 Retarded development following protein-energy malnutrition
0.000 0.570 0.429
E43 Unspecified severe protein-energy malnutrition
0.000 0.570 0.429
E42 Marasmic kwashiorkor
0.000 0.570 0.429
E41 Nutritional marasmus
0.000 0.570 0.429
E40 Kwashiorkor
0.000 0.570 0.429
G72 Other myopathies
0.429 0.571 0.000
E88 Other metabolic disorders
0.005 0.573 0.422
G25 Other extrapyramidal and movement disorders
0.426 0.574 0.000
E73.8 Other lactose intolerance
0.003 0.574 0.423
E73.1 Secondary lactase deficiency
0.003 0.574 0.423
E73.0 Congenital lactase deficiency
0.003 0.574 0.423
G06.2 Extradural and subdural abscess, unspecified
0.424 0.575 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.003 0.578 0.419
E89.8 Other postprocedural endocrine and metabolic disorders
0.003 0.578 0.419
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.003 0.578 0.419
E89.5 Postprocedural testicular hypofunction
0.003 0.578 0.419
E89.1 Postprocedural hypoinsulinaemia
0.003 0.578 0.419
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.578 0.422
E32 Diseases of thymus
0.000 0.578 0.422
E31 Polyglandular dysfunction
0.000 0.578 0.422
E30 Disorders of puberty, not elsewhere classified
0.000 0.578 0.422
E25 Adrenogenital disorders
0.000 0.578 0.422
G01 Meningitis in bacterial diseases classified elsewhere
0.422 0.578 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.579 0.421
L44 Other papulosquamous disorders
0.000 0.579 0.420
L41 Parapsoriasis
0.000 0.579 0.420
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.579 0.420
G06.0 Intracranial abscess and granuloma
0.419 0.581 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.419 0.581 0.000
E61 Deficiency of other nutrient elements
0.000 0.589 0.411
G40.9 Epilepsy, unspecified
0.411 0.589 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.409 0.591 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.409 0.591 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.409 0.591 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.591 0.409
E84.8 Cystic fibrosis with other manifestations
0.003 0.592 0.405
E84.1 Cystic fibrosis with intestinal manifestations
0.003 0.592 0.405
E84.0 Cystic fibrosis with pulmonary manifestations
0.003 0.592 0.405
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.405 0.595 0.000
G46.6 Pure sensory lacunar syndrome
0.405 0.595 0.000
G46.5 Pure motor lacunar syndrome
0.405 0.595 0.000
G46.3 Brain stem stroke syndrome
0.405 0.595 0.000
G46.2 Posterior cerebral artery syndrome
0.405 0.595 0.000
G46.1 Anterior cerebral artery syndrome
0.405 0.595 0.000
G46.0 Middle cerebral artery syndrome
0.405 0.595 0.000
G03.8 Meningitis due to other specified causes
0.404 0.595 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.404 0.595 0.000
G03.1 Chronic meningitis
0.404 0.595 0.000
G03.0 Nonpyogenic meningitis
0.404 0.595 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.597 0.403
G40.4 Other generalised epilepsy and epileptic syndromes
0.402 0.598 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.402 0.598 0.000
E83.3 Disorders of phosphorus metabolism
0.306 0.600 0.094
E89.2 Postprocedural hypoparathyroidism
0.003 0.602 0.395
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.602 0.398
G82 Paraplegia and tetraplegia
0.397 0.603 0.000
G43.3 Complicated migraine
0.394 0.605 0.000
G43.2 Status migrainosus
0.394 0.605 0.000
G43.0 Migraine without aura [common migraine]
0.394 0.606 0.000
E83.5 Disorders of calcium metabolism
0.376 0.607 0.017
G30.0 Alzheimer's disease with early onset
0.393 0.607 0.000
G24.4 Idiopathic orofacial dystonia
0.392 0.607 0.000
G24.3 Spasmodic torticollis
0.392 0.607 0.000
G24.2 Idiopathic nonfamilial dystonia
0.392 0.607 0.000
G24.1 Idiopathic familial dystonia
0.392 0.607 0.000
G24.0 Drug-induced dystonia
0.392 0.607 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.392 0.608 0.000
E73.9 Lactose intolerance, unspecified
0.003 0.608 0.389
M05 Seropositive rheumatoid arthritis
0.000 0.609 0.391
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.611 0.389
G83.4 Cauda equina syndrome
0.385 0.615 0.000
L42 Pityriasis rosea
0.000 0.616 0.384
G31.0 Circumscribed brain atrophy
0.382 0.618 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.618 0.382
E26 Hyperaldosteronism
0.000 0.618 0.381
M06.4 Inflammatory polyarthropathy
0.000 0.619 0.381
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.621 0.379
E29.1 Testicular hypofunction
0.000 0.623 0.377
E24.8 Other Cushing's syndrome
0.000 0.627 0.373
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.627 0.373
E24.3 Ectopic ACTH syndrome
0.000 0.627 0.373
E24.2 Drug-induced Cushing's syndrome
0.000 0.627 0.373
E24.1 Nelson's syndrome
0.000 0.627 0.373
E24.0 Pituitary-dependent Cushing's disease
0.000 0.627 0.373
G70.9 Myoneural disorder, unspecified
0.373 0.627 0.000
G43.1 Migraine with aura [classical migraine]
0.373 0.627 0.000
E20 Hypoparathyroidism
0.000 0.629 0.371
K90.9 Intestinal malabsorption, unspecified
0.000 0.629 0.371
G30.1 Alzheimer's disease with late onset
0.371 0.629 0.000
E28 Ovarian dysfunction
0.000 0.629 0.371
E23.0 Hypopituitarism
0.000 0.630 0.370
L43.3 Subacute (active) lichen planus
0.000 0.632 0.368
L43.2 Lichenoid drug reaction
0.000 0.632 0.368
L43.1 Bullous lichen planus
0.000 0.632 0.368
L43.0 Hypertrophic lichen planus
0.000 0.632 0.368
E89.4 Postprocedural ovarian failure
0.004 0.633 0.363
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.366 0.634 0.000
G10 Huntington's disease
0.365 0.634 0.000
G40.5 Special epileptic syndromes
0.365 0.635 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.637 0.362
E63 Other nutritional deficiencies
0.000 0.637 0.362
E56 Other vitamin deficiencies
0.000 0.637 0.362
E51 Thiamine deficiency
0.000 0.637 0.362
E50 Vitamin A deficiency
0.000 0.637 0.362
E60 Dietary zinc deficiency
0.000 0.637 0.362
E59 Dietary selenium deficiency
0.000 0.637 0.362
E58 Dietary calcium deficiency
0.000 0.637 0.362
E54 Ascorbic acid deficiency
0.000 0.637 0.362
E52 Niacin deficiency [pellagra]
0.000 0.637 0.362
M06.8 Other specified rheumatoid arthritis
0.000 0.639 0.361
M06.2 Rheumatoid bursitis
0.000 0.639 0.361
M06.1 Adult-onset Still's disease
0.000 0.639 0.361
G44.0 Cluster headache syndrome
0.358 0.642 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.643 0.357
M75 Shoulder lesions
0.000 0.643 0.357
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.356 0.644 0.000
G04.1 Tropical spastic paraplegia
0.356 0.644 0.000
G04.0 Acute disseminated encephalitis
0.356 0.644 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.355 0.645 0.000
G82.1 Spastic paraplegia
0.355 0.645 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.646 0.354
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.646 0.354
K90.1 Tropical sprue
0.000 0.646 0.354
M70-M79 Other soft tissue disorders
0.000 0.646 0.354
K90.8 Other intestinal malabsorption
0.000 0.647 0.353
M75.0 Adhesive capsulitis of shoulder
0.000 0.648 0.352
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.350 0.650 0.000
M06.3 Rheumatoid nodule
0.000 0.651 0.349
E84.9 Cystic fibrosis, unspecified
0.004 0.651 0.345
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.349 0.651 0.000
G02.1 Meningitis in mycoses
0.349 0.651 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.349 0.651 0.000
G83.8 Other specified paralytic syndromes
0.346 0.654 0.000
M75.4 Impingement syndrome of shoulder
0.000 0.654 0.346
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.655 0.345
G72.9 Myopathy, unspecified
0.345 0.655 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.656 0.344
E22.8 Other hyperfunction of pituitary gland
0.000 0.656 0.344
G80 Infantile cerebral palsy
0.344 0.656 0.000
E61.1 Iron deficiency
0.000 0.657 0.343
G00.8 Other bacterial meningitis
0.343 0.657 0.000
G00.3 Staphylococcal meningitis
0.343 0.657 0.000
G00.2 Streptococcal meningitis
0.343 0.657 0.000
G00.0 Haemophilus meningitis
0.343 0.657 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.658 0.342
G00.9 Bacterial meningitis, unspecified
0.342 0.658 0.000
G21.9 Secondary Parkinsonism, unspecified
0.341 0.659 0.000
G21.8 Other secondary Parkinsonism
0.341 0.659 0.000
G21.4 Vascular parkinsonism
0.341 0.659 0.000
G21.3 Postencephalitic Parkinsonism
0.341 0.659 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.341 0.659 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.341 0.659 0.000
G21.0 Malignant neuroleptic syndrome
0.341 0.659 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.341 0.659 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.341 0.659 0.000
G23.3 Multiple system atrophy, cerebellar type
0.341 0.659 0.000
G23.2 Striatonigral degeneration
0.341 0.659 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.341 0.659 0.000
G23.0 Hallervorden-Spatz disease
0.341 0.659 0.000
M45 Ankylosing spondylitis
0.000 0.660 0.340
G25.9 Extrapyramidal and movement disorder, unspecified
0.339 0.661 0.000
G40.8 Other epilepsy
0.338 0.661 0.000
G83.9 Paralytic syndrome, unspecified
0.338 0.662 0.000
E23.2 Diabetes insipidus
0.000 0.662 0.338
E22.1 Hyperprolactinaemia
0.000 0.662 0.338
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.337 0.662 0.000
G14 Postpolio syndrome
0.337 0.662 0.000
E34 Other endocrine disorders
0.000 0.663 0.337
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.663 0.337
G44.2 Tension-type headache
0.336 0.664 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.336 0.664 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.336 0.664 0.000
G00.1 Pneumococcal meningitis
0.335 0.665 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.666 0.333
E29.8 Other testicular dysfunction
0.000 0.666 0.333
E29.0 Testicular hyperfunction
0.000 0.666 0.333
L43.8 Other lichen planus
0.000 0.667 0.332
M79.6 Pain in limb
0.000 0.668 0.332
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.670 0.330
E23.1 Drug-induced hypopituitarism
0.000 0.670 0.330
M45-M49 Spondylopathies
0.000 0.670 0.330
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.671 0.329
M08 Juvenile arthritis
0.000 0.671 0.329
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.671 0.329
E23.6 Other disorders of pituitary gland
0.000 0.672 0.327
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.675 0.325
E55 Vitamin D deficiency
0.000 0.676 0.324
G24.5 Blepharospasm
0.323 0.677 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.678 0.322
M11 Other crystal arthropathies
0.000 0.678 0.322
G83.5 Locked-in syndrome
0.318 0.681 0.000
G83.3 Monoplegia, unspecified
0.318 0.681 0.000
G83.0 Diplegia of upper limbs
0.318 0.681 0.000
G70.8 Other specified myoneural disorders
0.318 0.682 0.000
G70.2 Congenital and developmental myasthenia
0.318 0.682 0.000
G70.1 Toxic myoneural disorders
0.318 0.682 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.003 0.682 0.315
E80.6 Other disorders of bilirubin metabolism
0.003 0.682 0.315
E80.5 Crigler-Najjar syndrome
0.003 0.682 0.315
E80.3 Defects of catalase and peroxydase
0.003 0.682 0.315
E80.2 Other porphyria
0.003 0.682 0.315
E80.0 Hereditary erythropoietic porphyria
0.003 0.682 0.315
G83.1 Monoplegia of lower limb
0.317 0.683 0.000
M07.6 Other enteropathic arthropathies
0.000 0.683 0.317
M07.5 Arthropathy in ulcerative colitis
0.000 0.683 0.317
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.683 0.317
M07.2 Psoriatic spondylitis
0.000 0.683 0.317
M07.1 Arthritis mutilans
0.000 0.683 0.317
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.683 0.317
G44.3 Chronic posttraumatic headache
0.315 0.684 0.000
G44.1 Vascular headache, not elsewhere classified
0.315 0.684 0.000
M79.60 Pain in limb (Multiple sites)
0.000 0.686 0.314
G11 Hereditary ataxia
0.313 0.687 0.000
G70.0 Myasthenia gravis
0.313 0.687 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.689 0.311
G41.8 Other status epilepticus
0.311 0.689 0.000
G41.2 Complex partial status epilepticus
0.311 0.689 0.000
G41.1 Petit mal status epilepticus
0.311 0.689 0.000
G41.0 Grand mal status epilepticus
0.311 0.689 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.689 0.310
M79.7 Fibromyalgia
0.000 0.691 0.309
M07.38 Other psoriatic arthropathies (Other)
0.000 0.691 0.308
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.691 0.308
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.691 0.308
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.691 0.308
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.691 0.308
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.691 0.308
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.691 0.308
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.691 0.308
E44.1 Mild protein-energy malnutrition
0.000 0.692 0.308
E44.0 Moderate protein-energy malnutrition
0.000 0.692 0.308
G72.8 Other specified myopathies
0.307 0.692 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.307 0.692 0.000
G72.3 Periodic paralysis
0.307 0.692 0.000
G72.2 Myopathy due to other toxic agents
0.307 0.692 0.000
G72.1 Alcoholic myopathy
0.307 0.692 0.000
G72.0 Drug-induced myopathy
0.307 0.692 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.692 0.308
G25.8 Other specified extrapyramidal and movement disorders
0.307 0.693 0.000
E88.9 Metabolic disorder, unspecified
0.004 0.694 0.303
E88.8 Other specified metabolic disorders
0.004 0.694 0.303
E88.3 Tumour lysis syndrome
0.004 0.694 0.303
E88.2 Lipomatosis, not elsewhere classified
0.004 0.694 0.303
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.694 0.306
G25.6 Drug-induced tics and other tics of organic origin
0.306 0.694 0.000
G25.5 Other chorea
0.306 0.694 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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