TreeWAS – Variant ID: rs28451064

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000	0.000
I25.2 Old myocardial infarction	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
I21.9 Acute myocardial infarction, unspecified	1.000	0.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.999	0.001	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.996	0.004	0.000
I20.0 Unstable angina	0.994	0.006	0.000
I25.5 Ischaemic cardiomyopathy	0.970	0.030	0.000
I24 Other acute ischaemic heart diseases	0.923	0.077	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.914	0.086	0.000
I22 Subsequent myocardial infarction	0.905	0.095	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.904	0.096	0.000
I25.3 Aneurysm of heart	0.857	0.143	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.833	0.167	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.823	0.177	0.000
Z95.0 Presence of cardiac pacemaker	0.813	0.187	0.000
I24.8 Other forms of acute ischaemic heart disease	0.782	0.218	0.000
I22.8 Subsequent myocardial infarction of other sites	0.752	0.248	0.000
Z95.2 Presence of prosthetic heart valve	0.728	0.272	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I25.4 Coronary artery aneurysm	0.670	0.330	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.669	0.331	0.000
I23 Certain current complications following acute myocardial infarction	0.664	0.336	0.000
I24.1 Dressler's syndrome	0.662	0.338	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.655	0.344	0.000
I20.1 Angina pectoris with documented spasm	0.639	0.361	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.627	0.372	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.613	0.387	0.000
Z95.4 Presence of other heart-valve replacement	0.610	0.390	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.593	0.407	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.573	0.427	0.000
I20.8 Other forms of angina pectoris	0.516	0.484	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.476	0.524	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.476	0.524	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.476	0.524	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.476	0.524	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.476	0.524	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.476	0.524	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.476	0.524	0.000
Z95.3 Presence of xenogenic heart valve	0.436	0.564	0.000
I23.8 Other current complications following acute myocardial infarction	0.423	0.577	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.380	0.620	0.000
I21.4 Acute subendocardial myocardial infarction	0.319	0.681	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.203	0.797	0.000
I50.1 Left ventricular failure	0.024	0.976	0.000
I50.9 Heart failure, unspecified	0.023	0.977	0.000
I50 Heart failure	0.023	0.977	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.977	0.023
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.000	0.978	0.022
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.000	0.978	0.022
D17 Benign lipomatous neoplasm	0.000	0.979	0.021
I50.0 Congestive heart failure	0.020	0.980	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.020	0.980	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.019	0.981	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.983	0.017
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.984	0.016
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.000	0.984	0.015
Z82.2 Family history of deafness and hearing loss	0.015	0.985	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.015	0.985	0.000
C71.2 Temporal lobe	0.014	0.986	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.014	0.986	0.000
Z82.1 Family history of blindness and visual loss	0.014	0.986	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.000	0.986	0.014
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.000	0.987	0.013
C71 Malignant neoplasm of brain	0.012	0.988	0.000
Z75 Problems related to medical facilities and other health care	0.012	0.988	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.011	0.988	0.000
C71.9 Brain, unspecified	0.011	0.989	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.011	0.989	0.000
C71.1 Frontal lobe	0.010	0.990	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.010	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
Z75.8 Other problems related to medical facilities and other health care	0.009	0.990	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.009	0.991	0.000
C71.7 Brain stem	0.009	0.991	0.000
C71.6 Cerebellum	0.009	0.991	0.000
C71.5 Cerebral ventricle	0.009	0.991	0.000
C71.4 Occipital lobe	0.009	0.991	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.009	0.991	0.000
Z75.0 Medical services not available in home	0.009	0.991	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.991	0.009
Z75.2 Other waiting period for investigation and treatment	0.009	0.991	0.000
C71.3 Parietal lobe	0.009	0.991	0.000
C71.8 Overlapping lesion of brain	0.008	0.991	0.000
Z75.5 Holiday relief care	0.008	0.992	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.008	0.992	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.008	0.992	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.993	0.007
I71 Aortic aneurysm and dissection	0.000	0.993	0.007
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.993	0.007
K76.6 Portal hypertension	0.000	0.993	0.007
S27.0 Traumatic pneumothorax	0.006	0.994	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.994	0.006
I71.0 Dissection of aorta [any part]	0.000	0.994	0.006
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.994	0.006
Z70-Z76 Persons encountering health services in other circumstances	0.006	0.994	0.000
J33.8 Other polyp of sinus	0.000	0.994	0.006
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.994	0.006
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.006	0.994	0.000
Z74 Problems related to care-provider dependency	0.006	0.994	0.000
G43.9 Migraine, unspecified	0.000	0.994	0.006
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.994	0.005
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.994	0.005
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.994	0.005
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.994	0.005
R09.1 Pleurisy	0.005	0.995	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.005	0.995	0.000
Z74.8 Other problems related to care-provider dependency	0.005	0.995	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.995	0.005
K70.3 Alcoholic cirrhosis of liver	0.000	0.995	0.005
N36.8 Other specified disorders of urethra	0.005	0.995	0.000
Z73 Problems related to life-management difficulty	0.005	0.995	0.000
I74 Arterial embolism and thrombosis	0.000	0.995	0.005
S22.10 Multiple fractures of thoracic spine (closed)	0.005	0.995	0.000
T39.0 Salicylates	0.005	0.995	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.005	0.995	0.000
H53.9 Visual disturbance, unspecified	0.005	0.995	0.000
J22 Unspecified acute lower respiratory infection	0.005	0.995	0.000
S27 Injury of other and unspecified intrathoracic organs	0.005	0.995	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.995	0.005
R09.2 Respiratory arrest	0.005	0.995	0.000
Z76 Persons encountering health services in other circumstances	0.005	0.995	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.004	0.995	0.000
K70.4 Alcoholic hepatic failure	0.000	0.995	0.005
Z74.0 Reduced mobility	0.005	0.995	0.000
K70 Alcoholic liver disease	0.000	0.995	0.005
M31.6 Other giant cell arteritis	0.000	0.995	0.004
Z89.5 Acquired absence of leg at or below knee	0.004	0.995	0.000
Z82.3 Family history of stroke	0.004	0.996	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.004	0.996	0.000
S22.1 Multiple fractures of thoracic spine	0.004	0.996	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.996	0.004
Z74.9 Problem related to care-provider dependency, unspecified	0.004	0.996	0.000
Z74.3 Need for continuous supervision	0.004	0.996	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.004	0.996	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
Z73.3 Stress, not elsewhere classified	0.004	0.996	0.000
H57.1 Ocular pain	0.004	0.996	0.000
Z89.6 Acquired absence of leg above knee	0.004	0.996	0.000
Z74.1 Need for assistance with personal care	0.004	0.996	0.000
Z89 Acquired absence of limb	0.004	0.996	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.004	0.996	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.996	0.004
Z76.3 Healthy person accompanying sick person	0.004	0.996	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.004	0.996	0.000
S27.2 Traumatic heamopneumothorax	0.004	0.996	0.000
H54 Blindness and low vision	0.004	0.996	0.000
H54.9 Unspecified visual impairment (binocular)	0.004	0.996	0.000
Z71.2 Person consulting for explanation of investigation findings	0.004	0.996	0.000
R15 Faecal incontinence	0.000	0.996	0.004
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.996	0.004
S22 Fracture of rib(s), sternum and thoracic spine	0.004	0.996	0.000
H54.7 Unspecified visual loss	0.004	0.996	0.000
Z71.6 Tobacco abuse counselling	0.004	0.996	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.004	0.996	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.004	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.996	0.004
Z73.6 Limitation of activities due to disability	0.004	0.996	0.000
Z73.5 Social role conflict, not elsewhere classified	0.004	0.996	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.004	0.996	0.000
Z73.2 Lack of relaxation and leisure	0.004	0.996	0.000
Z73.1 Accentuation of personality traits	0.004	0.996	0.000
Z73.0 Burn-out	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.996	0.004
K70.1 Alcoholic hepatitis	0.000	0.996	0.004
S20-S29 Injuries to the thorax	0.004	0.996	0.000
S27.9 Injury of unspecified intrathoracic organ	0.004	0.996	0.000
S27.8 Injury of other specified intrathoracic organs	0.004	0.996	0.000
S27.7 Multiple injuries of intrathoracic organs	0.004	0.996	0.000
S27.6 Injury of pleura	0.004	0.996	0.000
S27.5 Injury of thoracic trachea	0.004	0.996	0.000
S27.4 Injury of bronchus	0.004	0.996	0.000
H54.4 Blindness, one eye	0.004	0.996	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.003	0.996	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.996	0.003
S22.2 Fracture of sternum	0.004	0.996	0.000
Z70.9 Sex counselling, unspecified	0.003	0.996	0.000
Z70.8 Other sex counselling	0.003	0.996	0.000
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.003	0.996	0.000
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.003	0.996	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.003	0.996	0.000
Z70.0 Counselling related to sexual attitude	0.003	0.996	0.000
Z76.5 Malingerer [conscious situation]	0.003	0.996	0.000
Z76.4 Other boarder in health-care facility	0.003	0.996	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.003	0.996	0.000
Z76.1 Health supervision and care of foundling	0.003	0.996	0.000
Z76.0 Issue of repeat prescription	0.003	0.996	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.003	0.996	0.000
Z89.9 Acquired absence of limb, unspecified	0.003	0.996	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.996	0.003
S22.4 Multiple fractures of ribs	0.003	0.996	0.000
H54.1 Blindness, one eye, low vision, other eye	0.003	0.996	0.000
R09.0 Asphyxia	0.003	0.997	0.000
K70-K77 Diseases of liver	0.000	0.997	0.003
R09.3 Abnormal sputum	0.003	0.997	0.000
S27.1 Traumatic haemothorax	0.003	0.997	0.000
Z73.8 Other problems related to life-management difficulty	0.003	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.003	0.997	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.997	0.003
K73 Chronic hepatitis, not elsewhere classified	0.000	0.997	0.003
K73.9 Chronic hepatitis, unspecified	0.000	0.997	0.003
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.997	0.003
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.003	0.997	0.000
C70 Malignant neoplasm of meninges	0.003	0.997	0.000
I72 Other aneurysm	0.000	0.997	0.003
Z89.2 Acquired absence of upper limb above wrist	0.003	0.997	0.000
G43 Migraine	0.000	0.997	0.003
H06.2 Dysthyroid exophthalmos	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.003	0.997	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.997	0.003
S20.2 Contusion of thorax	0.003	0.997	0.000
S27.3 Other injuries of lung	0.003	0.997	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.003	0.997	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.003	0.997	0.000
Z89.1 Acquired absence of hand and wrist	0.003	0.997	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003
Z71.7 Human immunodeficiency virus [HIV] counselling	0.003	0.997	0.000
Z71.5 Drug abuse counselling and surveillance	0.003	0.997	0.000
Z71.0 Person consulting on behalf of another person	0.003	0.997	0.000
I78 Diseases of capillaries	0.000	0.997	0.003
I70 Atherosclerosis	0.000	0.997	0.003
S22.40 Multiple fractures of ribs (closed)	0.003	0.997	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
H54.6 Unqualified visual loss, one eye	0.003	0.997	0.000
H54.5 Low vision, one eye	0.003	0.997	0.000
H54.3 Unqualified visual loss, both eyes	0.003	0.997	0.000
H54.2 Low vision, both eyes	0.003	0.997	0.000
K76 Other diseases of liver	0.000	0.997	0.003
Z71.1 Person with feared complaint in whom no diagnosis is made	0.003	0.997	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.003	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.003	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.997	0.000
S20 Superficial injury of thorax	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.997	0.003
I72.8 Aneurysm of other specified arteries	0.000	0.997	0.003
Z43.2 Attention to ileostomy	0.003	0.997	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
S29 Other and unspecified injuries of thorax	0.003	0.997	0.000
S22.5 Flail chest	0.003	0.997	0.000
D22.0 Melanocytic naevi of lip	0.000	0.997	0.003
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.003	0.997	0.000
S26 Injury of heart	0.003	0.997	0.000
S25 Injury of blood vessels of thorax	0.003	0.997	0.000
S24 Injury of nerves and spinal cord at thorax level	0.003	0.997	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.003	0.997	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.003	0.997	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
S22.21 Fracture of sternum (open)	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
K70.0 Alcoholic fatty liver	0.000	0.997	0.003
S21 Open wound of thorax	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.003	0.997	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.997	0.003
S22.0 Fracture of thoracic vertebra	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
I72.2 Aneurysm of renal artery	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
K77 Liver disorders in diseases classified elsewhere	0.000	0.997	0.003
K71 Toxic liver disease	0.000	0.997	0.003
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.002	0.997	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.003	0.997	0.000
Z72 Problems related to lifestyle	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
G44.8 Other specified headache syndromes	0.000	0.997	0.003
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.997	0.003
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.997	0.003
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Z72.2 Drug use	0.003	0.997	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.997	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.997	0.003
I72.1 Aneurysm of artery of upper extremity	0.000	0.997	0.003
S20.0 Contusion of breast	0.003	0.997	0.000
C70.9 Meninges, unspecified	0.002	0.997	0.000
C70.1 Spinal meninges	0.002	0.997	0.000
C70.0 Cerebral meninges	0.002	0.997	0.000
C72.9 Central nervous system, unspecified	0.002	0.997	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.002	0.997	0.000
C72.5 Other and unspecified cranial nerves	0.002	0.997	0.000
C72.4 Acoustic nerve	0.002	0.997	0.000
C72.3 Optic nerve	0.002	0.997	0.000
C72.2 Olfactory nerve	0.002	0.997	0.000
C72.1 Cauda equina	0.002	0.997	0.000
C72.0 Spinal cord	0.002	0.997	0.000
G43.3 Complicated migraine	0.000	0.997	0.003
G43.2 Status migrainosus	0.000	0.997	0.003
G43.0 Migraine without aura [common migraine]	0.000	0.997	0.003
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.997	0.003
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.002	0.997	0.000
I72.3 Aneurysm of iliac artery	0.000	0.997	0.003
I78.1 Naevus, nonneoplastic	0.000	0.997	0.003
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.003
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.002
I79.1 Aortitis in diseases classified elsewhere	0.000	0.997	0.002
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.997	0.002
K74.5 Biliary cirrhosis, unspecified	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.997	0.002
S22.3 Fracture of rib	0.003	0.997	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.997	0.002
I70.8 Atherosclerosis of other arteries	0.000	0.997	0.002
I78.9 Disease of capillaries, unspecified	0.000	0.997	0.002
I78.8 Other diseases of capillaries	0.000	0.997	0.002
G43.8 Other migraine	0.000	0.997	0.002
G44.0 Cluster headache syndrome	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.997	0.002
K76.4 Peliosis hepatis	0.000	0.997	0.002
K76.3 Infarction of liver	0.000	0.997	0.002
K76.2 Central haemorrhagic necrosis of liver	0.000	0.997	0.002
K76.1 Chronic passive congestion of liver	0.000	0.997	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.002	0.997	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.002	0.997	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.002	0.997	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.002	0.997	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.997	0.002
S20.7 Multiple superficial injuries of thorax	0.002	0.997	0.000
S20.4 Other superficial injuries of back wall of thorax	0.002	0.997	0.000
S20.1 Other and unspecified superficial injuries of breast	0.002	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.997	0.000
K74.3 Primary biliary cirrhosis	0.000	0.997	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.997	0.000
T39.2 Pyrazolone derivatives	0.002	0.997	0.000
K75 Other inflammatory liver diseases	0.000	0.997	0.002
K74.4 Secondary biliary cirrhosis	0.000	0.998	0.002
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.998	0.002
K74.1 Hepatic sclerosis	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.998	0.002
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.002
J20-J22 Other acute lower respiratory infections	0.002	0.998	0.000
S29.9 Unspecified injury of thorax	0.002	0.998	0.000
S22.51 Flail chest (open)	0.002	0.998	0.000
K76.9 Liver disease, unspecified	0.000	0.998	0.002
S29.8 Other specified injuries of thorax	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.002	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.002	0.998	0.000
S23.4 Sprain and strain of ribs and sternum	0.002	0.998	0.000
S23.3 Sprain and strain of thoracic spine	0.002	0.998	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.002	0.998	0.000
S23.1 Dislocation of thoracic vertebra	0.002	0.998	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.002	0.998	0.000
S24.6 Injury of unspecified nerve of thorax	0.002	0.998	0.000
S24.5 Injury of other nerves of thorax	0.002	0.998	0.000
S24.4 Injury of thoracic sympathetic nerves	0.002	0.998	0.000
S24.3 Injury of peripheral nerves of thorax	0.002	0.998	0.000
S24.2 Injury of nerve root of thoracic spine	0.002	0.998	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.002	0.998	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.002	0.998	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.002	0.998	0.000
S25.8 Injury of other blood vessels of thorax	0.002	0.998	0.000
S25.7 Injury of multiple blood vessels of thorax	0.002	0.998	0.000
S25.5 Injury of intercostal blood vessels	0.002	0.998	0.000
S25.4 Injury of pulmonary blood vessels	0.002	0.998	0.000
S25.3 Injury of innominate or subclavian vein	0.002	0.998	0.000
S25.2 Injury of superior vena cava	0.002	0.998	0.000
S25.1 Injury of innominate or subclavian artery	0.002	0.998	0.000
S25.0 Injury of thoracic aorta	0.002	0.998	0.000
S26.9 Injury of heart, unspecified	0.002	0.998	0.000
S26.8 Other injuries of heart	0.002	0.998	0.000
S26.0 Injury of heart with haemopericardium	0.002	0.998	0.000
S28.1 Traumatic amputation of part of thorax	0.002	0.998	0.000
S28.0 Crushed chest	0.002	0.998	0.000
D22 Melanocytic naevi	0.000	0.998	0.002
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.998	0.002
G45.3 Amaurosis fugax	0.000	0.998	0.002
K56.4 Other impaction of intestine	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
G44 Other headache syndromes	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
I72.9 Aneurysm of unspecified site	0.000	0.998	0.002
I72.0 Aneurysm of carotid artery	0.000	0.998	0.002
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.6 Orbit	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
C69.0 Conjunctiva	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
N36.2 Urethral caruncle	0.002	0.998	0.000
S21.9 Open wound of thorax, part unspecified	0.002	0.998	0.000
S21.8 Open wound of other parts of thorax	0.002	0.998	0.000
S21.7 Multiple open wounds of thoracic wall	0.002	0.998	0.000
S21.1 Open wound of front wall of thorax	0.002	0.998	0.000
S21.0 Open wound of breast	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.002	0.998	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
H53-H54 Visual disturbances and blindness	0.002	0.998	0.000
C69.9 Eye, unspecified	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
K71.9 Toxic liver disease, unspecified	0.000	0.998	0.002
K71.8 Toxic liver disease with other disorders of liver	0.000	0.998	0.002
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.998	0.002
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.998	0.002
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.998	0.002
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.998	0.002
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.998	0.002
K71.2 Toxic liver disease with acute hepatitis	0.000	0.998	0.002
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.998	0.002
K71.0 Toxic liver disease with cholestasis	0.000	0.998	0.002
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.998	0.002
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
T42.4 Benzodiazepines	0.002	0.998	0.000
Z72.9 Problem related to lifestyle, unspecified	0.002	0.998	0.000
Z72.6 Gambling and betting	0.002	0.998	0.000
Z72.5 High-risk sexual behaviour	0.002	0.998	0.000
Z72.4 Inappropriate diet and eating habits	0.002	0.998	0.000
Z72.3 Lack of physical exercise	0.002	0.998	0.000
I77 Other disorders of arteries and arterioles	0.000	0.998	0.002
D22.9 Melanocytic naevi, unspecified	0.000	0.998	0.002
R06.4 Hyperventilation	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
N36 Other disorders of urethra	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.002	0.998	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.998	0.002
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations