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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28480606
log Bayes Factor = 9.70409
Chromosome 15   position 78,762,313  (GRCh37) Explore rs28480606 on Ensembl!
Variant rs28480606 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I60-I69 Cerebrovascular diseases
0.000 0.000 1.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.001 0.999
I69 Sequelae of cerebrovascular disease
0.000 0.001 0.999
I71 Aortic aneurysm and dissection
0.000 0.002 0.998
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.004 0.996
I67 Other cerebrovascular diseases
0.000 0.005 0.995
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.009 0.991
I60 Subarachnoid haemorrhage
0.000 0.012 0.988
I73 Other peripheral vascular diseases
0.000 0.014 0.986
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.015 0.985
I67.9 Cerebrovascular disease, unspecified
0.000 0.020 0.980
I73.9 Peripheral vascular disease, unspecified
0.000 0.023 0.977
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.023 0.977
I70 Atherosclerosis
0.000 0.025 0.975
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.028 0.972
J40-J47 Chronic lower respiratory diseases
0.000 0.037 0.963
J43 Emphysema
0.000 0.041 0.959
J43.9 Emphysema, unspecified
0.000 0.043 0.957
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.043 0.957
I67.1 Cerebral aneurysm, nonruptured
0.000 0.053 0.947
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.053 0.947
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.054 0.946
J42 Unspecified chronic bronchitis
0.000 0.055 0.945
I60.8 Other subarachnoid haemorrhage
0.000 0.069 0.931
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.070 0.930
I69.3 Sequelae of cerebral infarction
0.000 0.074 0.926
I77 Other disorders of arteries and arterioles
0.000 0.100 0.900
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.119 0.881
Chapter IX Diseases of the circulatory system
0.000 0.123 0.877
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.125 0.875
I72 Other aneurysm
0.000 0.130 0.870
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.135 0.865
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.149 0.851
I67.8 Other specified cerebrovascular diseases
0.000 0.161 0.839
I73.0 Raynaud's syndrome
0.000 0.172 0.828
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.173 0.827
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.179 0.821
I74 Arterial embolism and thrombosis
0.000 0.185 0.815
I77.0 Arteriovenous fistula, acquired
0.000 0.196 0.804
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.217 0.783
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.224 0.776
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.233 0.767
I70.0 Atherosclerosis of aorta
0.000 0.236 0.764
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.237 0.763
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.245 0.755
I72.8 Aneurysm of other specified arteries
0.000 0.246 0.754
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.275 0.725
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.279 0.721
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.284 0.715
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.284 0.715
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.284 0.715
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.284 0.715
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.286 0.714
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.286 0.714
I67.5 Moyamoya disease
0.000 0.286 0.714
I67.4 Hypertensive encephalopathy
0.000 0.286 0.714
I67.3 Progressive vascular leukoencephalopathy
0.000 0.286 0.714
I61 Intracerebral haemorrhage
0.000 0.288 0.712
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.291 0.708
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.291 0.708
I72.0 Aneurysm of carotid artery
0.000 0.292 0.707
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.293 0.707
I78 Diseases of capillaries
0.000 0.299 0.701
I70.9 Generalised and unspecified atherosclerosis
0.000 0.301 0.699
I70.8 Atherosclerosis of other arteries
0.000 0.301 0.699
J43.2 Centrilobular emphysema
0.000 0.302 0.698
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.306 0.693
I71.0 Dissection of aorta [any part]
0.000 0.309 0.691
J41 Simple and mucopurulent chronic bronchitis
0.000 0.309 0.690
J43.1 Panlobular emphysema
0.000 0.312 0.687
J43.0 MacLeod's syndrome
0.000 0.312 0.687
I72.9 Aneurysm of unspecified site
0.000 0.314 0.686
I77.1 Stricture of artery
0.000 0.320 0.680
I77.2 Rupture of artery
0.000 0.322 0.678
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.335 0.665
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.340 0.660
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.344 0.656
I72.4 Aneurysm of artery of lower extremity
0.000 0.351 0.649
I77.5 Necrosis of artery
0.000 0.354 0.646
I77.4 Coeliac artery compression syndrome
0.000 0.354 0.646
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.361 0.639
I63 Cerebral infarction
0.000 0.369 0.631
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.370 0.630
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.371 0.629
I70.1 Atherosclerosis of renal artery
0.000 0.372 0.628
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.376 0.624
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.376 0.624
I72.1 Aneurysm of artery of upper extremity
0.000 0.376 0.624
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.377 0.623
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.383 0.617
I74.8 Embolism and thrombosis of other arteries
0.000 0.384 0.616
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.384 0.616
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.386 0.614
J43.8 Other emphysema
0.000 0.389 0.611
I00-I02 Acute rheumatic fever
0.000 0.394 0.606
I27 Other pulmonary heart diseases
0.000 0.394 0.606
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.405 0.595
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.408 0.591
I27.9 Pulmonary heart disease, unspecified
0.000 0.414 0.586
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.421 0.579
I68.0 Cerebral amyloid angiopathy
0.000 0.421 0.579
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.430 0.570
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.437 0.563
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.444 0.556
I79.1 Aortitis in diseases classified elsewhere
0.000 0.444 0.556
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.444 0.556
I72.3 Aneurysm of iliac artery
0.000 0.449 0.551
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.450 0.550
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.452 0.548
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.459 0.541
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.459 0.541
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.459 0.541
I26 Pulmonary embolism
0.000 0.468 0.532
I77.3 Arterial fibromuscular dysplasia
0.000 0.470 0.530
I72.2 Aneurysm of renal artery
0.000 0.470 0.530
I73.8 Other specified peripheral vascular diseases
0.000 0.474 0.526
I74.5 Embolism and thrombosis of iliac artery
0.000 0.475 0.525
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.483 0.517
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.491 0.509
I28 Other diseases of pulmonary vessels
0.000 0.491 0.509
I77.8 Other specified disorders of arteries and arterioles
0.000 0.496 0.504
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.496 0.504
I78.9 Disease of capillaries, unspecified
0.000 0.497 0.503
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.499 0.501
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.499 0.501
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.499 0.501
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.499 0.501
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.500 0.500
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.503 0.497
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.503 0.497
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.503 0.497
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.503 0.497
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.505 0.495
J41.1 Mucopurulent chronic bronchitis
0.000 0.505 0.495
J41.0 Simple chronic bronchitis
0.000 0.505 0.495
I62 Other nontraumatic intracranial haemorrhage
0.000 0.506 0.494
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.512 0.487
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.515 0.484
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.520 0.480
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.520 0.480
I78.8 Other diseases of capillaries
0.000 0.521 0.479
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.521 0.479
E11 Non-insulin-dependent diabetes mellitus
0.000 0.525 0.475
I61.8 Other intracerebral haemorrhage
0.000 0.527 0.473
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.535 0.464
J46 Status asthmaticus
0.000 0.540 0.460
I67.2 Cerebral atherosclerosis
0.000 0.543 0.457
E11.4 With neurological complications
0.000 0.545 0.455
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.547 0.453
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.547 0.453
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.547 0.452
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.549 0.450
E11.3 With ophthalmic complications
0.000 0.551 0.449
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.555 0.445
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.558 0.441
E11.5 With peripheral circulatory complications
0.000 0.562 0.438
I02 Rheumatic chorea
0.000 0.565 0.435
I01 Rheumatic fever with heart involvement
0.000 0.565 0.435
I27.1 Kyphoscoliotic heart disease
0.000 0.565 0.435
I27.8 Other specified pulmonary heart diseases
0.000 0.571 0.429
E11.0 With coma
0.000 0.576 0.424
E11.2 With renal complications
0.000 0.578 0.422
E11.8 With unspecified complications
0.000 0.584 0.416
J40 Bronchitis, not specified as acute or chronic
0.000 0.585 0.415
I00 Rheumatic fever without mention of heart involvement
0.000 0.587 0.413
E11.6 With other specified complications
0.000 0.589 0.411
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.592 0.408
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.611 0.389
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.620 0.380
E10-E14 Diabetes mellitus
0.000 0.632 0.368
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.633 0.367
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.635 0.365
I28.1 Aneurysm of pulmonary artery
0.000 0.635 0.365
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.635 0.365
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.639 0.361
E11.1 With ketoacidosis
0.000 0.642 0.358
I28.8 Other specified diseases of pulmonary vessels
0.000 0.643 0.356
I63.9 Cerebral infarction, unspecified
0.000 0.644 0.356
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.645 0.355
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.652 0.347
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.652 0.347
I62.1 Nontraumatic extradural haemorrhage
0.000 0.653 0.347
I78.1 Naevus, nonneoplastic
0.000 0.653 0.347
E11.7 With multiple complications
0.000 0.660 0.340
I77.6 Arteritis, unspecified
0.000 0.660 0.340
I27.0 Primary pulmonary hypertension
0.000 0.662 0.338
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.667 0.333
E14 Unspecified diabetes mellitus
0.000 0.672 0.328
J92.0 Pleural plaque with presence of asbestos
0.000 0.685 0.315
E13 Other specified diabetes mellitus
0.000 0.687 0.313
E14.9 Without complications
0.000 0.687 0.313
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.688 0.312
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.688 0.312
I01.8 Other acute rheumatic heart disease
0.000 0.688 0.312
I01.2 Acute rheumatic myocarditis
0.000 0.688 0.312
I01.1 Acute rheumatic endocarditis
0.000 0.688 0.312
I01.0 Acute rheumatic pericarditis
0.000 0.688 0.312
I02.9 Rheumatic chorea without heart involvement
0.000 0.688 0.312
I02.0 Rheumatic chorea with heart involvement
0.000 0.688 0.312
J92 Pleural plaque
0.000 0.698 0.302
Chapter X Diseases of the respiratory system
0.000 0.701 0.299
I65.2 Occlusion and stenosis of carotid artery
0.000 0.708 0.292
J90-J94 Other diseases of pleura
0.000 0.713 0.287
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.713 0.287
I05-I09 Chronic rheumatic heart diseases
0.000 0.714 0.285
J60-J70 Lung diseases due to external agents
0.000 0.715 0.285
I63.8 Other cerebral infarction
0.000 0.721 0.279
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.723 0.277
E13.9 Without complications
0.000 0.726 0.274
E12 Malnutrition-related diabetes mellitus
0.000 0.736 0.264
E10 Insulin-dependent diabetes mellitus
0.000 0.741 0.259
I65.1 Occlusion and stenosis of basilar artery
0.001 0.748 0.251
J92.9 Pleural plaque without asbestos
0.000 0.752 0.248
E10.1 With ketoacidosis
0.000 0.752 0.248
E14.3 With ophthalmic complications
0.000 0.753 0.247
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.755 0.245
E14.1 With ketoacidosis
0.000 0.760 0.240
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.763 0.237
E14.7 With multiple complications
0.000 0.765 0.235
E14.0 With coma
0.000 0.765 0.235
E14.8 With unspecified complications
0.000 0.765 0.235
J95-J99 Other diseases of the respiratory system
0.000 0.767 0.233
E14.4 With neurological complications
0.000 0.768 0.232
I09 Other rheumatic heart diseases
0.000 0.771 0.229
E13.8 With unspecified complications
0.000 0.775 0.225
E13.7 With multiple complications
0.000 0.775 0.225
E13.6 With other specified complications
0.000 0.775 0.225
E13.5 With peripheral circulatory complications
0.000 0.775 0.225
E13.4 With neurological complications
0.000 0.775 0.225
E13.3 With ophthalmic complications
0.000 0.775 0.225
E13.2 With renal complications
0.000 0.775 0.225
E13.1 With ketoacidosis
0.000 0.775 0.225
E13.0 With coma
0.000 0.775 0.225
J60 Coalworker's pneumoconiosis
0.000 0.775 0.225
E14.6 With other specified complications
0.000 0.777 0.223
J69 Pneumonitis due to solids and liquids
0.000 0.783 0.217
J86 Pyothorax
0.000 0.784 0.216
J64 Unspecified pneumoconiosis
0.000 0.788 0.212
J45 Asthma
0.000 0.790 0.210
E14.5 With peripheral circulatory complications
0.000 0.791 0.209
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.795 0.204
J66 Airway disease due to specific organic dust
0.000 0.795 0.204
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.795 0.204
J62 Pneumoconiosis due to dust containing silica
0.000 0.795 0.204
J65 Pneumoconiosis associated with tuberculosis
0.000 0.795 0.204
J86.9 Pyothorax without fistula
0.000 0.801 0.198
J98 Other respiratory disorders
0.000 0.803 0.197
J70 Respiratory conditions due to other external agents
0.000 0.806 0.193
E10.0 With coma
0.000 0.807 0.193
E14.2 Withrenal complications
0.000 0.807 0.192
E10.6 With other specified complications
0.000 0.809 0.191
E12.9 Without complications
0.000 0.811 0.189
E12.8 With unspecified complications
0.000 0.811 0.189
E12.7 With multiple complications
0.000 0.811 0.189
E12.6 With other specified complications
0.000 0.811 0.189
E12.5 With peripheral circulatory complications
0.000 0.811 0.189
E12.4 With neurological complications
0.000 0.811 0.189
E12.3 With ophthalmic complications
0.000 0.811 0.189
E12.2 With renal complications
0.000 0.811 0.189
E12.1 With ketoacidosis
0.000 0.811 0.189
E12.0 With coma
0.000 0.811 0.189
I06 Rheumatic aortic valve diseases
0.000 0.811 0.189
I09.9 Rheumatic heart disease, unspecified
0.000 0.812 0.188
E10.4 With neurological complications
0.000 0.817 0.183
I07 Rheumatic tricuspid valve diseases
0.000 0.818 0.182
E10.3 With ophthalmic complications
0.000 0.820 0.180
I27.2 Other secondary pulmonary hypertension
0.000 0.821 0.179
J98.1 Pulmonary collapse
0.000 0.822 0.178
J93 Pneumothorax
0.000 0.824 0.176
J69.8 Pneumonitis due to other solids and liquids
0.000 0.827 0.173
J98.9 Respiratory disorder, unspecified
0.000 0.829 0.171
E10.5 With peripheral circulatory complications
0.000 0.831 0.168
J96 Respiratory failure, not elsewhere classified
0.000 0.833 0.167
E10.7 With multiple complications
0.000 0.834 0.166
I09.8 Other specified rheumatic heart diseases
0.000 0.836 0.164
I09.2 Chronic rheumatic pericarditis
0.000 0.836 0.164
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.836 0.164
I09.0 Rheumatic myocarditis
0.000 0.836 0.164
I05 Rheumatic mitral valve diseases
0.000 0.836 0.163
E10.2 With renal complications
0.000 0.838 0.162
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.839 0.161
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.840 0.160
E10.8 With unspecified complications
0.000 0.843 0.157
J69.1 Pneumonitis due to oils and essences
0.000 0.844 0.156
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.845 0.155
J85 Abscess of lung and mediastinum
0.000 0.846 0.154
I10-I15 Hypertensive diseases
0.000 0.847 0.153
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.848 0.152
J45.8 Mixed asthma
0.000 0.849 0.151
J45.1 Nonallergic asthma
0.000 0.849 0.151
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.001 0.850 0.150
J93.1 Other spontaneous pneumothorax
0.000 0.850 0.150
J69.0 Pneumonitis due to food and vomit
0.000 0.851 0.149
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.853 0.147
J62.0 Pneumoconiosis due to talc dust
0.000 0.853 0.147
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.853 0.147
J63.5 Stannosis
0.000 0.853 0.147
J63.4 Siderosis
0.000 0.853 0.147
J63.3 Graphite fibrosis (of lung)
0.000 0.853 0.147
J63.2 Berylliosis
0.000 0.853 0.147
J63.1 Bauxite fibrosis (of lung)
0.000 0.853 0.147
J63.0 Aluminosis (of lung)
0.000 0.853 0.147
J66.8 Airway disease due to other specific organic dusts
0.000 0.853 0.147
J66.2 Cannabinosis
0.000 0.853 0.147
J66.1 Flax-dresser's disease
0.000 0.853 0.147
J66.0 Byssinosis
0.000 0.853 0.147
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.853 0.147
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.853 0.147
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.853 0.147
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.853 0.147
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.853 0.147
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.853 0.147
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.853 0.147
J91 Pleural effusion in conditions classified elsewhere
0.000 0.853 0.147
J86.0 Pyothorax with fistula
0.000 0.853 0.146
J98.3 Compensatory emphysema
0.000 0.858 0.142
J98.4 Other disorders of lung
0.000 0.859 0.141
J94 Other pleural conditions
0.000 0.859 0.141
J67 Hypersensitivity pneumonitis due to organic dust
0.001 0.861 0.139
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.861 0.139
J70.8 Respiratory conditions due to other specified external agents
0.000 0.861 0.139
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.861 0.139
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.861 0.139
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.861 0.139
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.861 0.139
J98.2 Interstitial emphysema
0.000 0.862 0.138
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.864 0.135
I06.8 Other rheumatic aortic valve diseases
0.000 0.864 0.135
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.864 0.135
I06.1 Rheumatic aortic insufficiency
0.000 0.864 0.135
J20-J22 Other acute lower respiratory infections
0.000 0.865 0.135
I05.1 Rheumatic mitral insufficiency
0.000 0.867 0.133
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.867 0.133
I07.9 Tricuspid valve disease, unspecified
0.000 0.869 0.131
I07.8 Other tricuspid valve diseases
0.000 0.869 0.131
I07.2 Tricuspid stenosis with insufficiency
0.000 0.869 0.131
I07.0 Tricuspid stenosis
0.000 0.869 0.131
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.872 0.128
J95.8 Other postprocedural respiratory disorders
0.000 0.876 0.124
I95 Hypotension
0.000 0.878 0.122
J93.0 Spontaneous tension pneumothorax
0.000 0.880 0.120
J96.9 Respiratory failure, unspecified
0.000 0.880 0.120
J96.1 Chronic respiratory failure
0.000 0.880 0.120
J96.0 Acute respiratory failure
0.000 0.880 0.120
I06.0 Rheumatic aortic stenosis
0.000 0.880 0.119
J95.0 Tracheostomy malfunction
0.000 0.881 0.119
J98.6 Disorders of diaphragm
0.000 0.882 0.117
I05.8 Other mitral valve diseases
0.000 0.882 0.117
J95.5 Postprocedural subglottic stenosis
0.000 0.884 0.116
J95.4 Mendelson's syndrome
0.000 0.884 0.116
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.884 0.116
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.884 0.116
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.884 0.116
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.887 0.113
J00-J06 Acute upper respiratory infections
0.000 0.887 0.113
J99.0 Rheumatoid lung disease
0.000 0.887 0.113
I05.0 Mitral stenosis
0.000 0.889 0.111
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.889 0.111
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.889 0.111
I98.0 Cardiovascular syphilis
0.000 0.889 0.111
J85.3 Abscess of mediastinum
0.000 0.889 0.111
J85.0 Gangrene and necrosis of lung
0.000 0.889 0.111
J85.1 Abscess of lung with pneumonia
0.000 0.889 0.111
I05.2 Mitral stenosis with insufficiency
0.000 0.890 0.110
I13 Hypertensive heart and renal disease
0.000 0.890 0.110
J98.8 Other specified respiratory disorders
0.000 0.890 0.109
I07.1 Tricuspid insufficiency
0.000 0.892 0.108
J93.8 Other pneumothorax
0.000 0.892 0.108
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.893 0.106
J20 Acute bronchitis
0.000 0.895 0.104
J94.1 Fibrothorax
0.000 0.896 0.104
I15 Secondary hypertension
0.000 0.897 0.103
I95.1 Orthostatic hypotension
0.000 0.897 0.103
I95.8 Other hypotension
0.000 0.898 0.102
J94.9 Pleural condition, unspecified
0.000 0.899 0.101
J94.0 Chylous effusion
0.000 0.899 0.101
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.899 0.101
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.899 0.101
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.900 0.100
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.001 0.900 0.100
J67.7 Air-conditioner and humidifier lung
0.001 0.900 0.100
J67.6 Maple-bark-stripper's lung
0.001 0.900 0.100
J67.5 Mushroom-worker's lung
0.001 0.900 0.100
J67.4 Maltworker's lung
0.001 0.900 0.100
J67.3 Suberosis
0.001 0.900 0.100
J67.1 Bagassosis
0.001 0.900 0.100
J67.0 Farmer's lung
0.001 0.900 0.100
I99 Other and unspecified disorders of circulatory system
0.000 0.903 0.097
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.904 0.096
I97.0 Postcardiotomy syndrome
0.000 0.904 0.096
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.906 0.093
J21 Acute bronchiolitis
0.000 0.908 0.092
J85.2 Abscess of lung without pneumonia
0.000 0.911 0.089
E10.9 Without complications
0.000 0.912 0.088
J67.2 Bird fancier's lung
0.001 0.912 0.087
J94.8 Other specified pleural conditions
0.000 0.913 0.086
J00 Acute nasopharyngitis [common cold]
0.000 0.913 0.087
J96.09 Acute respiratory failure; Type unspecified
0.000 0.914 0.086
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.914 0.086
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.914 0.086
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.914 0.086
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.914 0.086
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.914 0.086
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.914 0.086
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.914 0.086
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.914 0.086
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.917 0.083
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.917 0.083
J20.9 Acute bronchitis, unspecified
0.000 0.919 0.081
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.920 0.079
I11 Hypertensive heart disease
0.000 0.920 0.080
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.921 0.079
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.921 0.079
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.921 0.079
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.921 0.079
I15.9 Seconday hypertension, unspecified
0.000 0.921 0.079
J93.9 Pneumothorax, unspecified
0.000 0.922 0.078
J20.8 Acute bronchitis due to other specified organisms
0.000 0.923 0.077
I12 Hypertensive renal disease
0.000 0.923 0.077
I95.0 Idiopathic hypotension
0.000 0.924 0.075
J20.7 Acute bronchitis due to echovirus
0.000 0.925 0.075
J20.6 Acute bronchitis due to rhinovirus
0.000 0.925 0.075
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.925 0.075
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.925 0.075
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.925 0.075
J20.2 Acute bronchitis due to streptococcus
0.000 0.925 0.075
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.925 0.075
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.925 0.075
I15.8 Other secondary hypertension
0.000 0.926 0.074
I15.2 Hypertension secondary to endocrine disorders
0.000 0.926 0.074
I15.1 Hypertension secondary to other renal disorders
0.000 0.926 0.074
J04 Acute laryngitis and tracheitis
0.000 0.926 0.074
I97.1 Other functional disturbances following cardiac surgery
0.000 0.927 0.073
J01 Acute sinusitis
0.000 0.928 0.072
J03 Acute tonsillitis
0.000 0.931 0.069
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.934 0.066
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.934 0.066
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.934 0.066
J02 Acute pharyngitis
0.000 0.936 0.064
J09-J18 Influenza and pneumonia
0.000 0.937 0.063
J21.9 Acute bronchiolitis, unspecified
0.000 0.938 0.061
I15.0 Renovascular hypertension
0.000 0.938 0.061
I05.9 Mitral valve disease, unspecified
0.000 0.939 0.061
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.939 0.061
J05.1 Acute epiglottitis
0.000 0.939 0.061
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.001 0.940 0.059
J05.0 Acute obstructive laryngitis [croup]
0.000 0.940 0.059
E11.9 Without complications
0.000 0.942 0.058
J94.2 Haemothorax
0.001 0.943 0.057
J90 Pleural effusion, not elsewhere classified
0.000 0.943 0.057
J45.0 Predominantly allergic asthma
0.000 0.943 0.057
J01.0 Acute maxillary sinusitis
0.000 0.944 0.056
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.944 0.056
J04.2 Acute laryngotracheitis
0.000 0.947 0.053
J01.8 Other acute sinusitis
0.000 0.948 0.052
J01.4 Acute pansinusitis
0.000 0.948 0.052
J01.3 Acute sphenoidal sinusitis
0.000 0.948 0.052
J01.1 Acute frontal sinusitis
0.000 0.948 0.052
J10 Influenza due to identified influenza virus
0.000 0.949 0.051
J04.0 Acute laryngitis
0.000 0.949 0.051
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.950 0.050
J03.0 Streptococcal tonsillitis
0.000 0.950 0.050
J02.0 Streptococcal pharyngitis
0.000 0.950 0.049
I12.9 Hypertensive renal disease without renal failure
0.000 0.951 0.049
J04.1 Acute tracheitis
0.000 0.951 0.049
I95.2 Hypotension due to drugs
0.000 0.952 0.048
J01.2 Acute ethmoidal sinusitis
0.000 0.953 0.047
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.954 0.046
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.954 0.045
J09 Influenza due to certain identified influenza virus
0.000 0.954 0.045
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.956 0.044
J47 Bronchiectasis
0.000 0.956 0.044
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.956 0.044
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.956 0.044
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.957 0.042
J01.9 Acute sinusitis, unspecified
0.000 0.957 0.042
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.959 0.041
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.959 0.041
J17 Pneumonia in diseases classified elsewhere
0.000 0.959 0.040
J12 Viral pneumonia, not elsewhere classified
0.000 0.959 0.040
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.960 0.040
J14 Pneumonia due to Haemophilus influenzae
0.000 0.960 0.040
J06.0 Acute laryngopharyngitis
0.000 0.961 0.039
J03.9 Acute tonsillitis, unspecified
0.000 0.963 0.037
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.963 0.037
I85 Oesophageal varices
0.000 0.964 0.036
I81 Portal vein thrombosis
0.000 0.964 0.036
I12.0 Hypertensive renal disease with renal failure
0.000 0.965 0.035
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.966 0.034
I88 Nonspecific lymphadenitis
0.000 0.966 0.034
I95.9 Hypotension, unspecified
0.000 0.967 0.033
J15.2 Pneumonia due to staphylococcus
0.000 0.967 0.033
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.967 0.033
J16.0 Chlamydial pneumonia
0.000 0.967 0.033
J06.9 Acute upper respiratory infection, unspecified
0.000 0.967 0.033
I85.0 Oesophageal varices with bleeding
0.000 0.968 0.032
J11 Influenza, virus not identified
0.000 0.969 0.031
N64 Other disorders of breast
0.031 0.969 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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