TreeWAS – Variant ID: rs28534808

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.001	0.999
J45 Asthma	0.000	0.001	0.998
J40-J47 Chronic lower respiratory diseases	0.000	0.002	0.998
E03 Other hypothyroidism	0.000	0.002	0.998
# Top node	0.004	0.003	0.993
Chapter X Diseases of the respiratory system	0.001	0.003	0.996
E00-E07 Disorders of thyroid gland	0.000	0.003	0.997
K90 Intestinal malabsorption	0.000	0.004	0.996
Chapter XI Diseases of the digestive system	0.000	0.005	0.995
K90-K93 Other diseases of the digestive system	0.000	0.005	0.995
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.006	0.993
Chapter II Neoplasms	0.000	0.009	0.991
C44 Other malignant neoplasms of skin	0.000	0.010	0.990
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.010	0.990
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.011	0.989
C44.3 Skin of other and unspecified parts of face	0.000	0.012	0.988
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.015	0.985
J44 Other chronic obstructive pulmonary disease	0.000	0.017	0.983
M06.9 Rheumatoid arthritis, unspecified	0.000	0.017	0.983
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.018	0.982
K29 Gastritis and duodenitis	0.000	0.019	0.981
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.019	0.981
D60-D64 Aplastic and other anaemias	0.000	0.021	0.979
K29.8 Duodenitis	0.000	0.022	0.978
D64 Other anaemias	0.000	0.025	0.975
D64.9 Anaemia, unspecified	0.000	0.027	0.973
K20 Oesophagitis	0.000	0.041	0.959
J00-J06 Acute upper respiratory infections	0.000	0.043	0.956
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.069	0.931
C44.7 Skin of lower limb, including hip	0.000	0.070	0.930
D00-D09 In situ neoplasms	0.000	0.084	0.916
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.088	0.912
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.090	0.910
J20-J22 Other acute lower respiratory infections	0.001	0.101	0.898
D06 Carcinoma in situ of cervix uteri	0.000	0.107	0.893
J46 Status asthmaticus	0.000	0.109	0.891
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.118	0.882
J02 Acute pharyngitis	0.000	0.123	0.877
D06.9 Cervix, unspecified	0.000	0.124	0.876
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.559	0.130	0.311
C51-C58 Malignant neoplasms of female genital organs	0.000	0.132	0.868
K29.4 Chronic atrophic gastritis	0.000	0.136	0.864
C44.0 Skin of lip	0.000	0.139	0.861
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.145	0.855
K22 Other diseases of oesophagus	0.000	0.148	0.852
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.153	0.847
K70-K77 Diseases of liver	0.000	0.156	0.844
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.160	0.840
E05.9 Thyrotoxicosis, unspecified	0.000	0.160	0.840
J22 Unspecified acute lower respiratory infection	0.000	0.162	0.838
J90-J94 Other diseases of pleura	0.001	0.164	0.835
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.166	0.834
C64-C68 Malignant neoplasms of urinary tract	0.000	0.167	0.833
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.177	0.822
J02.9 Acute pharyngitis, unspecified	0.000	0.179	0.821
E06 Thyroiditis	0.000	0.186	0.814
E50-E64 Other nutritional deficiencies	0.000	0.188	0.812
M05-M14 Inflammatory polyarthropathies	0.430	0.188	0.382
M06 Other rheumatoid arthritis	0.172	0.192	0.636
K22.1 Ulcer of oesophagus	0.000	0.194	0.806
K50-K52 Noninfective enteritis and colitis	0.005	0.195	0.801
J90 Pleural effusion, not elsewhere classified	0.000	0.197	0.803
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.208	0.792
E10-E14 Diabetes mellitus	0.000	0.214	0.786
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.214	0.785
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.223	0.776
J03 Acute tonsillitis	0.000	0.224	0.776
C67 Malignant neoplasm of bladder	0.000	0.224	0.776
K51 Ulcerative colitis	0.002	0.224	0.774
K26 Duodenal ulcer	0.000	0.225	0.775
C53 Malignant neoplasm of cervix uteri	0.000	0.227	0.773
K29.5 Chronic gastritis, unspecified	0.000	0.227	0.773
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.230	0.770
C54 Malignant neoplasm of corpus uteri	0.000	0.231	0.769
K22.2 Oesophageal obstruction	0.000	0.234	0.766
K70 Alcoholic liver disease	0.000	0.235	0.765
K35-K38 Diseases of appendix	0.000	0.237	0.763
D62 Acute posthaemorrhagic anaemia	0.000	0.238	0.762
K27 Peptic ulcer, site unspecified	0.000	0.240	0.760
K29.1 Other acute gastritis	0.000	0.240	0.760
C44.1 Skin of eyelid, including canthus	0.000	0.241	0.759
C44.4 Skin of scalp and neck	0.000	0.245	0.755
K51.9 Ulcerative colitis, unspecified	0.000	0.245	0.754
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.251	0.749
D80-D89 Certain disorders involving the immune mechanism	0.000	0.251	0.748
D45 Polycythaemia vera	0.000	0.253	0.747
M80-M85 Disorders of bone density and structure	0.473	0.261	0.266
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.262	0.738
C67.9 Bladder, unspecified	0.000	0.262	0.738
C73 Malignant neoplasm of thyroid gland	0.000	0.268	0.732
J04 Acute laryngitis and tracheitis	0.000	0.269	0.730
E11 Non-insulin-dependent diabetes mellitus	0.000	0.280	0.720
J01 Acute sinusitis	0.000	0.281	0.719
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.001	0.284	0.715
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.284	0.716
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.284	0.716
J45.8 Mixed asthma	0.000	0.284	0.716
J45.1 Nonallergic asthma	0.000	0.284	0.716
J41 Simple and mucopurulent chronic bronchitis	0.000	0.285	0.715
E03.5 Myxoedema coma	0.000	0.285	0.715
E03.4 Atrophy of thyroid (acquired)	0.000	0.285	0.715
E03.3 Postinfectious hypothyroidism	0.000	0.285	0.715
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.285	0.715
E03.1 Congenital hypothyroidism without goitre	0.000	0.285	0.715
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.285	0.715
Chapter XVI Certain conditions originating in the perinatal period	0.003	0.285	0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.285	0.714
E00 Congenital iodine-deficiency syndrome	0.000	0.285	0.714
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.285	0.714
K90.8 Other intestinal malabsorption	0.000	0.286	0.714
K90.3 Pancreatic steatorrhoea	0.000	0.286	0.714
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.286	0.714
K90.1 Tropical sprue	0.000	0.286	0.714
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.287	0.713
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.287	0.713
C40-C41 Malignant neoplasms of bone and articular cartilage	0.000	0.289	0.711
K29.2 Alcoholic gastritis	0.000	0.289	0.711
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.290	0.710
C44.8 Overlapping lesion of skin	0.000	0.290	0.710
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.291	0.709
K28 Gastrojejunal ulcer	0.000	0.291	0.709
K23 Disorders of oesophagus in diseases classified elsewhere	0.000	0.291	0.709
E07 Other disorders of thyroid	0.000	0.292	0.708
D05 Carcinoma in situ of breast	0.000	0.293	0.707
C81 Hodgkin's disease	0.000	0.294	0.706
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.294	0.705
C53.9 Cervix uteri, unspecified	0.000	0.295	0.705
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.295	0.705
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.295	0.705
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.295	0.705
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.296	0.704
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.296	0.704
K29.9 Gastroduodenitis, unspecified	0.000	0.297	0.703
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.298	0.702
J00 Acute nasopharyngitis [common cold]	0.000	0.299	0.701
Chapter XXII Codes for special purposes	0.003	0.300	0.697
D64.8 Other specified anaemias	0.000	0.301	0.699
D64.4 Congenital dyserythropoietic anaemia	0.000	0.301	0.699
D64.3 Other sideroblastic anaemias	0.000	0.301	0.699
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.301	0.699
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.301	0.699
D64.0 Hereditary sideroblastic anaemia	0.000	0.301	0.699
D55-D59 Haemolytic anaemias	0.000	0.301	0.699
K92 Other diseases of digestive system	0.000	0.301	0.699
E55 Vitamin D deficiency	0.000	0.301	0.698
E20-E35 Disorders of other endocrine glands	0.000	0.301	0.698
K70.9 Alcoholic liver disease, unspecified	0.000	0.302	0.698
C54.1 Endometrium	0.000	0.303	0.697
K29.3 Chronic superficial gastritis	0.000	0.303	0.697
E11.3 With ophthalmic complications	0.000	0.304	0.696
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.304	0.696
Z85 Personal history of malignant neoplasm	0.000	0.309	0.691
K51.2 Ulcerative (chronic) proctitis	0.001	0.313	0.686
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.314	0.686
E06.3 Autoimmune thyroiditis	0.000	0.317	0.683
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.318	0.682
J95-J99 Other diseases of the respiratory system	0.001	0.322	0.677
K22.9 Disease of oesophagus, unspecified	0.000	0.330	0.670
K51.8 Other ulcerative colitis	0.001	0.336	0.663
J45.0 Predominantly allergic asthma	0.000	0.339	0.660
E03.8 Other specified hypothyroidism	0.000	0.342	0.658
D69 Purpura and other haemorrhagic conditions	0.000	0.342	0.657
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.343	0.657
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.343	0.657
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.343	0.657
C44.2 Skin of ear and external auricular canal	0.000	0.343	0.657
E05.8 Other thyrotoxicosis	0.000	0.347	0.652
E05.5 Thyroid crisis or storm	0.000	0.347	0.652
E05.4 Thyrotoxicosis factitia	0.000	0.347	0.652
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.347	0.652
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.347	0.652
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.348	0.652
C09 Malignant neoplasm of tonsil	0.000	0.348	0.652
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.349	0.651
M86-M90 Other osteopathies	0.484	0.349	0.166
K72 Hepatic failure, not elsewhere classified	0.000	0.351	0.649
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.351	0.649
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.352	0.648
J03.9 Acute tonsillitis, unspecified	0.000	0.353	0.647
J21 Acute bronchiolitis	0.001	0.356	0.644
K29.0 Acute haemorrhagic gastritis	0.000	0.357	0.643
C44.5 Skin of trunk	0.000	0.359	0.641
C92 Myeloid leukaemia	0.000	0.359	0.641
D06.7 Other parts of cervix	0.000	0.360	0.640
D06.1 Exocervix	0.000	0.360	0.640
D06.0 Endocervix	0.000	0.360	0.640
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.360	0.640
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.361	0.639
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.362	0.638
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.363	0.637
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.367	0.633
M60-M63 Disorders of muscles	0.424	0.367	0.209
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.367	0.633
C95 Leukaemia of unspecified cell type	0.000	0.367	0.633
C94 Other leukaemias of specified cell type	0.000	0.367	0.633
C93 Monocytic leukaemia	0.000	0.367	0.633
C86 Other specified types of T/NK-cell lymphoma	0.000	0.367	0.633
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.367	0.633
M00-M03 Infectious arthropathies	0.420	0.368	0.212
Chapter I Certain infectious and parasitic diseases	0.000	0.369	0.631
M65-M68 Disorders of synovium and tendon	0.517	0.370	0.113
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.371	0.629
J02.0 Streptococcal pharyngitis	0.000	0.371	0.629
K90.9 Intestinal malabsorption, unspecified	0.000	0.372	0.628
K92.0 Haematemesis	0.000	0.372	0.628
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.373	0.627
C51 Malignant neoplasm of vulva	0.000	0.376	0.623
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.377	0.622
C58 Malignant neoplasm of placenta	0.000	0.377	0.622
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.377	0.622
C52 Malignant neoplasm of vagina	0.000	0.377	0.622
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.381	0.619
C91 Lymphoid leukaemia	0.000	0.382	0.618
E55.9 Vitamin D deficiency, unspecified	0.000	0.382	0.617
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.423	0.388	0.188
E11.4 With neurological complications	0.000	0.389	0.611
K22.3 Perforation of oesophagus	0.000	0.389	0.611
D46 Myelodysplastic syndromes	0.000	0.389	0.611
D75 Other diseases of blood and blood-forming organs	0.000	0.390	0.610
C67.4 Posterior wall of bladder	0.000	0.391	0.609
E04 Other non-toxic goitre	0.000	0.391	0.609
C60-C63 Malignant neoplasms of male genital organs	0.000	0.391	0.609
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.392	0.607
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.392	0.607
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.392	0.607
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.392	0.607
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.392	0.607
J20 Acute bronchitis	0.001	0.395	0.604
K77 Liver disorders in diseases classified elsewhere	0.000	0.395	0.605
K73 Chronic hepatitis, not elsewhere classified	0.000	0.395	0.605
K71 Toxic liver disease	0.000	0.395	0.605
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.397	0.602
C74 Malignant neoplasm of adrenal gland	0.000	0.397	0.602
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.398	0.602
J94 Other pleural conditions	0.001	0.399	0.600
D86 Sarcoidosis	0.000	0.400	0.600
D47.2 Monoclonal gammopathy	0.000	0.400	0.600
D69.6 Thrombocytopenia, unspecified	0.000	0.400	0.600
J06.9 Acute upper respiratory infection, unspecified	0.000	0.400	0.600
M91-M94 Chondropathies	0.372	0.401	0.227
D09 Carcinoma in situ of other and unspecified sites	0.000	0.402	0.598
M70-M79 Other soft tissue disorders	0.544	0.402	0.054
M50-M54 Other dorsopathies	0.542	0.403	0.056
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.403	0.597
C66 Malignant neoplasm of ureter	0.000	0.403	0.597
C65 Malignant neoplasm of renal pelvis	0.000	0.403	0.597
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.404	0.596
K65-K67 Diseases of peritoneum	0.000	0.406	0.594
E53 Deficiency of other B group vitamins	0.000	0.406	0.594
K26.4 Chronic or unspecified with haemorrhage	0.000	0.407	0.593
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.407	0.593
C88 Malignant immunoproliferative diseases	0.000	0.408	0.592
D50-D53 Nutritional anaemias	0.000	0.408	0.591
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.409	0.591
B35-B49 Mycoses	0.000	0.410	0.590
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.410	0.589
K31 Other diseases of stomach and duodenum	0.000	0.413	0.587
E06.9 Thyroiditis, unspecified	0.000	0.416	0.583
E06.5 Other chronic thyroiditis	0.000	0.416	0.583
E06.4 Drug-induced thyroiditis	0.000	0.416	0.583
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.416	0.583
E06.1 Subacute thyroiditis	0.000	0.416	0.583
E06.0 Acute thyroiditis	0.000	0.416	0.583
D05.1 Intraductal carcinoma in situ	0.000	0.418	0.582
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.418	0.582
E63 Other nutritional deficiencies	0.000	0.418	0.582
E56 Other vitamin deficiencies	0.000	0.418	0.582
E51 Thiamine deficiency	0.000	0.418	0.582
E50 Vitamin A deficiency	0.000	0.418	0.582
E60 Dietary zinc deficiency	0.000	0.418	0.582
E59 Dietary selenium deficiency	0.000	0.418	0.582
E58 Dietary calcium deficiency	0.000	0.418	0.582
E54 Ascorbic acid deficiency	0.000	0.418	0.582
E52 Niacin deficiency [pellagra]	0.000	0.418	0.582
M14 Arthropathies in other diseases classified elsewhere	0.308	0.418	0.274
M12 Other specific arthropathies	0.308	0.418	0.274
M09 Juvenile arthritis in diseases classified elsewhere	0.308	0.418	0.274
M08 Juvenile arthritis	0.308	0.418	0.274
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.419	0.581
K22.4 Dyskinesia of oesophagus	0.000	0.420	0.580
C85.1 B-cell lymphoma, unspecified	0.000	0.420	0.580
K75 Other inflammatory liver diseases	0.000	0.420	0.580
M06.8 Other specified rheumatoid arthritis	0.123	0.421	0.456
M06.4 Inflammatory polyarthropathy	0.123	0.421	0.456
M06.3 Rheumatoid nodule	0.123	0.421	0.456
M06.2 Rheumatoid bursitis	0.123	0.421	0.456
M06.1 Adult-onset Still's disease	0.123	0.421	0.456
C81.9 Hodgkin's disease, unspecified	0.000	0.421	0.579
K70.3 Alcoholic cirrhosis of liver	0.000	0.422	0.578
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.423	0.577
K35 Acute appendicitis	0.000	0.424	0.576
K76 Other diseases of liver	0.000	0.424	0.576
M13 Other arthritis	0.411	0.425	0.165
E40-E46 Malnutrition	0.001	0.425	0.574
K70.4 Alcoholic hepatic failure	0.000	0.426	0.574
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.426	0.574
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.427	0.573
M06.0 Seronegative rheumatoid arthritis	0.119	0.429	0.452
D04 Carcinoma in situ of skin	0.000	0.429	0.570
K22.8 Other specified diseases of oesophagus	0.000	0.430	0.570
M05 Seropositive rheumatoid arthritis	0.255	0.431	0.315
J04.0 Acute laryngitis	0.000	0.431	0.569
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.432	0.568
C13 Malignant neoplasm of hypopharynx	0.000	0.432	0.568
C11 Malignant neoplasm of nasopharynx	0.000	0.432	0.568
C10 Malignant neoplasm of oropharynx	0.000	0.432	0.568
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.432	0.568
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.432	0.568
C05 Malignant neoplasm of palate	0.000	0.432	0.568
C04 Malignant neoplasm of floor of mouth	0.000	0.432	0.568
C03 Malignant neoplasm of gum	0.000	0.432	0.568
C00 Malignant neoplasm of lip	0.000	0.432	0.568
C12 Malignant neoplasm of pyriform sinus	0.000	0.432	0.568
C07 Malignant neoplasm of parotid gland	0.000	0.432	0.568
M11 Other crystal arthropathies	0.308	0.433	0.259
M07 Psoriatic and enteropathic arthropathies	0.270	0.435	0.295
B37 Candidiasis	0.000	0.435	0.565
K26.7 Chronic without haemorrhage or perforation	0.000	0.435	0.564
J60-J70 Lung diseases due to external agents	0.001	0.436	0.563
E12 Malnutrition-related diabetes mellitus	0.000	0.436	0.564
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.437	0.563
C82.6 Cutaneous follicle centre lymphoma	0.000	0.437	0.563
C82.5 Diffuse follicle centre lymphoma	0.000	0.437	0.563
C82.4 Follicular lymphoma grade IIIb	0.000	0.437	0.563
C82.3 Follicular lymphoma grade IIIa	0.000	0.437	0.563
C82.2 Large cell, follicular	0.000	0.437	0.563
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.437	0.563
C82.0 Small cleaved cell, follicular	0.000	0.437	0.563
M40-M43 Deforming dorsopathies	0.366	0.437	0.197
K37 Unspecified appendicitis	0.000	0.437	0.563
D61 Other aplastic anaemias	0.000	0.438	0.561
D67 Hereditary factor IX deficiency	0.000	0.443	0.557
D66 Hereditary factor VIII deficiency	0.000	0.443	0.557
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.443	0.557
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.443	0.556
J03.0 Streptococcal tonsillitis	0.000	0.443	0.556
C67.8 Overlapping lesion of bladder	0.000	0.443	0.556
C67.7 Urachus	0.000	0.443	0.556
C67.3 Anterior wall of bladder	0.000	0.443	0.556
C67.1 Dome of bladder	0.000	0.443	0.556
C67.0 Trigone of bladder	0.000	0.443	0.556
K51.1 Ulcerative (chronic) ileocolitis	0.001	0.443	0.555
K38 Other diseases of appendix	0.000	0.444	0.556
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.444	0.556
K26.2 Acute with both haemorrhage and perforation	0.000	0.444	0.556
K26.1 Acute with perforation	0.000	0.444	0.556
K26.0 Acute with haemorrhage	0.000	0.444	0.556
C53.8 Overlapping lesion of cervix uteri	0.000	0.446	0.554
C53.1 Exocervix	0.000	0.446	0.554
C53.0 Endocervix	0.000	0.446	0.554
C09.9 Tonsil, unspecified	0.000	0.448	0.551
C54.9 Corpus uteri, unspecified	0.000	0.449	0.551
C54.8 Overlapping lesion of corpus uteri	0.000	0.449	0.551
C54.3 Fundus uteri	0.000	0.449	0.551
C54.2 Myometrium	0.000	0.449	0.551
C54.0 Isthmus uteri	0.000	0.449	0.551
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.450	0.550
J01.9 Acute sinusitis, unspecified	0.000	0.451	0.549
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.452	0.548
K70.0 Alcoholic fatty liver	0.000	0.452	0.548
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.452	0.548
K36 Other appendicitis	0.000	0.453	0.547
K25 Gastric ulcer	0.000	0.453	0.547
M84 Disorders of continuity of bone	0.426	0.453	0.120
M79 Other soft tissue disorders, not elsewhere classified	0.540	0.454	0.005
K27.7 Chronic without haemorrhage or perforation	0.000	0.455	0.545
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.455	0.545
K27.5 Chronic or unspecified with perforation	0.000	0.455	0.545
K27.4 Chronic or unspecified with haemorrhage	0.000	0.455	0.545
K27.3 Acute without haemorrhage or perforation	0.000	0.455	0.545
K27.2 Acute with both haemorrhage and perforation	0.000	0.455	0.545
K27.1 Acute with perforation	0.000	0.455	0.545
K27.0 Acute with haemorrhage	0.000	0.455	0.545
E21.0 Primary hyperparathyroidism	0.000	0.456	0.544
C67.6 Ureteric orifice	0.000	0.457	0.543
E07.9 Disorder of thyroid, unspecified	0.000	0.458	0.542
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.458	0.542
M79.6 Pain in limb	0.538	0.461	0.001
C01 Malignant neoplasm of base of tongue	0.000	0.462	0.538
E29 Testicular dysfunction	0.000	0.462	0.537
J06.8 Other acute upper respiratory infections of multiple sites	0.000	0.463	0.537
J06.0 Acute laryngopharyngitis	0.000	0.463	0.537
D84 Other immunodeficiencies	0.000	0.463	0.537
D83 Common variable immunodeficiency	0.000	0.463	0.537
D82 Immunodeficiency associated with other major defects	0.000	0.463	0.537
D81 Combined immunodeficiencies	0.000	0.463	0.537
D80 Immunodeficiency with predominantly antibody defects	0.000	0.463	0.537
M54 Dorsalgia	0.531	0.464	0.005
B37.8 Candidiasis of other sites	0.000	0.465	0.535
D75.1 Secondary polycythaemia	0.000	0.465	0.535
C67.2 Lateral wall of bladder	0.000	0.466	0.534
E61 Deficiency of other nutrient elements	0.000	0.466	0.533
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.467	0.533
K92.1 Melaena	0.000	0.467	0.533
E13 Other specified diabetes mellitus	0.000	0.467	0.533
E11.5 With peripheral circulatory complications	0.000	0.467	0.533
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.000	0.467	0.533
M79.66 Pain in limb (Lower leg)	0.531	0.469	0.000
M83 Adult osteomalacia	0.339	0.470	0.191
M82 Osteoporosis in diseases classified elsewhere	0.339	0.470	0.191
M45-M49 Spondylopathies	0.398	0.471	0.131
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.471	0.529
C85.0 Lymphosarcoma	0.000	0.471	0.529
D63.0 Anaemia in neoplastic disease	0.000	0.471	0.529
M81 Osteoporosis without pathological fracture	0.269	0.474	0.257
J04.2 Acute laryngotracheitis	0.000	0.476	0.524
J04.1 Acute tracheitis	0.000	0.476	0.524
K70.1 Alcoholic hepatitis	0.000	0.476	0.524
M54.9 Dorsalgia, unspecified	0.523	0.476	0.001
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.002	0.478	0.520
E14 Unspecified diabetes mellitus	0.000	0.478	0.522
M89 Other disorders of bone	0.431	0.478	0.090
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.479	0.521
K26.5 Chronic or unspecified with perforation	0.000	0.479	0.521
M85 Other disorders of bone density and structure	0.351	0.479	0.169
K74 Fibrosis and cirrhosis of liver	0.000	0.482	0.518
C67.5 Bladder neck	0.000	0.483	0.517
C92.0 Acute myeloid leukaemia	0.000	0.483	0.517
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.484	0.516
E11.8 With unspecified complications	0.000	0.484	0.516
E11.7 With multiple complications	0.000	0.484	0.516
E11.6 With other specified complications	0.000	0.484	0.516
J01.8 Other acute sinusitis	0.000	0.484	0.516
J01.4 Acute pansinusitis	0.000	0.484	0.516
J01.3 Acute sphenoidal sinusitis	0.000	0.484	0.516
J01.2 Acute ethmoidal sinusitis	0.000	0.484	0.516
J01.1 Acute frontal sinusitis	0.000	0.484	0.516
J01.0 Acute maxillary sinusitis	0.000	0.484	0.516
J86 Pyothorax	0.001	0.485	0.515
K22.5 Diverticulum of oesophagus, acquired	0.000	0.485	0.515
D48.5 Skin	0.000	0.485	0.515
M80 Osteoporosis with pathological fracture	0.345	0.485	0.170
M79.67 Pain in limb (Ankle and foot)	0.514	0.486	0.000
J85 Abscess of lung and mediastinum	0.001	0.486	0.513
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.486	0.513
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.486	0.513
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.486	0.513
D47.4 Osteomyelofibrosis	0.000	0.486	0.513
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.486	0.513
K22.0 Achalasia of cardia	0.000	0.487	0.513
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.487	0.513
J41.1 Mucopurulent chronic bronchitis	0.000	0.487	0.513
J41.0 Simple chronic bronchitis	0.000	0.487	0.513
P90-P96 Other disorders originating in the perinatal period	0.002	0.487	0.510
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.002	0.487	0.510
P75-P78 Digestive system disorders of fetus and newborn	0.002	0.487	0.510
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.002	0.487	0.510
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.002	0.487	0.510
P35-P39 Infections specific to the perinatal period	0.002	0.487	0.510
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.002	0.487	0.510
P10-P15 Birth trauma	0.002	0.487	0.510
P05-P08 Disorders related to length of gestation and fetal growth	0.002	0.487	0.510
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.002	0.487	0.510
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.488	0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.488	0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.488	0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.488	0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.488	0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.488	0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.488	0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.488	0.512
Z85.5 Personal history of malignant neoplasm of urinary tract	0.000	0.488	0.512
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.488	0.511
K93.1 Megacolon in Chagas' disease	0.000	0.488	0.511
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.488	0.511
M20-M25 Other joint disorders	0.495	0.490	0.016
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.000	0.490	0.510
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.000	0.490	0.510
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.000	0.490	0.510
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.491	0.509
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.000	0.491	0.508
K23.1 Megaoesophagus in Chagas' disease	0.000	0.491	0.508
K23.0 Tuberculous oesophagitis	0.000	0.491	0.508
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.491	0.508
K28.7 Chronic without haemorrhage or perforation	0.000	0.491	0.508
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.491	0.508
K28.5 Chronic or unspecified with perforation	0.000	0.491	0.508
K28.4 Chronic or unspecified with haemorrhage	0.000	0.491	0.508
K28.3 Acute without haemorrhage or perforation	0.000	0.491	0.508
K28.2 Acute with both haemorrhage and perforation	0.000	0.491	0.508
K28.1 Acute with perforation	0.000	0.491	0.508
K28.0 Acute with haemorrhage	0.000	0.491	0.508
E23 Hypofunction and other disorders of pituitary gland	0.000	0.492	0.508
M65 Synovitis and tenosynovitis	0.472	0.492	0.036
E07.1 Dyshormogenetic goitre	0.000	0.492	0.508
E07.0 Hypersecretion of calcitonin	0.000	0.492	0.508
D05.7 Other carcinoma in situ of breast	0.000	0.493	0.507
D05.0 Lobular carcinoma in situ	0.000	0.493	0.507
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.493	0.506
C81.7 Other Hodgkin's disease	0.000	0.494	0.506
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.494	0.506
C81.3 Lymphocytic depletion	0.000	0.494	0.506
C81.2 Mixed cellularity	0.000	0.494	0.506
C81.1 Nodular sclerosis	0.000	0.494	0.506
C81.0 Lymphocytic predominance	0.000	0.494	0.506
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.494	0.506
D74 Methaemoglobinaemia	0.000	0.494	0.506
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.494	0.506

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations