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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857164
log Bayes Factor = 80.5587
Chromosome 6   position 32,758,219  (GRCh37) Explore rs2857164 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
D00-D09 In situ neoplasms
0.000 0.001 0.999
D04 Carcinoma in situ of skin
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
G37 Other demyelinating diseases of central nervous system
0.996 0.004 0.000
C44 Other malignant neoplasms of skin
0.000 0.005 0.995
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.005 0.995
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.006 0.994
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.006 0.994
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.006 0.994
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
Chapter II Neoplasms
0.000 0.007 0.993
L57.0 Actinic keratosis
0.000 0.008 0.992
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.008 0.992
C44.7 Skin of lower limb, including hip
0.000 0.009 0.991
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.010 0.990
E70-E90 Metabolic disorders
0.000 0.012 0.988
C44.6 Skin of upper limb, including shoulder
0.000 0.012 0.988
L40.5 Arthropathic psoriasis
0.000 0.018 0.982
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.019 0.981
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.021 0.979
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.022 0.978
D04.5 Skin of trunk
0.000 0.022 0.978
D04.7 Skin of lower limb, including hip
0.000 0.026 0.974
D06 Carcinoma in situ of cervix uteri
0.000 0.026 0.974
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.027 0.973
H36.0 Diabetic retinopathy
0.000 0.029 0.971
L40 Psoriasis
0.000 0.031 0.969
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.033 0.967
E10.1 With ketoacidosis
0.000 0.040 0.960
C83.3 Large cell (diffuse)
0.000 0.040 0.960
E89.0 Postprocedural hypothyroidism
0.000 0.044 0.956
D06.9 Cervix, unspecified
0.000 0.045 0.955
E78.0 Pure hypercholesterolaemia
0.000 0.046 0.954
E10.5 With peripheral circulatory complications
0.000 0.050 0.950
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.051 0.949
C44.3 Skin of other and unspecified parts of face
0.000 0.060 0.940
D09 Carcinoma in situ of other and unspecified sites
0.000 0.061 0.939
M06.0 Seronegative rheumatoid arthritis
0.000 0.061 0.939
L40.9 Psoriasis, unspecified
0.000 0.063 0.937
E83.1 Disorders of iron metabolism
0.926 0.074 0.000
D04.3 Skin of other and unspecified parts of face
0.000 0.078 0.922
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.078 0.922
L40-L45 Papulosquamous disorders
0.000 0.079 0.921
M06.3 Rheumatoid nodule
0.000 0.086 0.914
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.087 0.913
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.087 0.913
E20-E35 Disorders of other endocrine glands
0.000 0.094 0.906
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.106 0.894
E10.4 With neurological complications
0.000 0.108 0.892
E10.0 With coma
0.000 0.111 0.889
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.117 0.883
E78.6 Lipoprotein deficiency
0.000 0.119 0.881
E10.2 With renal complications
0.000 0.119 0.881
D04.4 Skin of scalp and neck
0.000 0.120 0.880
D09.0 Bladder
0.000 0.121 0.879
G37.8 Other specified demyelinating diseases of central nervous system
0.878 0.122 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.123 0.877
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.125 0.875
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.131 0.869
E27 Other disorders of adrenal gland
0.000 0.132 0.868
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.137 0.863
C91 Lymphoid leukaemia
0.000 0.142 0.858
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.855 0.145 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.148 0.852
C82.0 Small cleaved cell, follicular
0.000 0.150 0.850
C85.1 B-cell lymphoma, unspecified
0.000 0.151 0.849
E06 Thyroiditis
0.000 0.152 0.848
C43 Malignant melanoma of skin
0.000 0.152 0.848
H36 Retinal disorders in diseases classified elsewhere
0.000 0.154 0.846
D03 Melanoma in situ
0.000 0.156 0.844
C82.2 Large cell, follicular
0.000 0.161 0.839
E10.8 With unspecified complications
0.000 0.165 0.835
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.168 0.832
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.174 0.826
E78.5 Hyperlipidaemia, unspecified
0.000 0.174 0.826
E23 Hypofunction and other disorders of pituitary gland
0.000 0.176 0.824
E11.5 With peripheral circulatory complications
0.000 0.181 0.819
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.182 0.818
D04.9 Skin, unspecified
0.000 0.184 0.816
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.185 0.815
E78.2 Mixed hyperlipidaemia
0.000 0.186 0.814
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.193 0.807
E06.3 Autoimmune thyroiditis
0.000 0.199 0.801
E10.6 With other specified complications
0.000 0.200 0.800
E11.1 With ketoacidosis
0.000 0.204 0.796
C44.4 Skin of scalp and neck
0.000 0.204 0.796
E88 Other metabolic disorders
0.000 0.204 0.796
E89.3 Postprocedural hypopituitarism
0.000 0.211 0.789
C44.0 Skin of lip
0.000 0.212 0.788
E89.2 Postprocedural hypoparathyroidism
0.000 0.214 0.786
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.214 0.786
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.214 0.786
E16 Other disorders of pancreatic internal secretion
0.000 0.215 0.785
E89.4 Postprocedural ovarian failure
0.000 0.215 0.785
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.215 0.784
E11.0 With coma
0.000 0.217 0.783
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.227 0.773
E79 Disorders of purine and pyrimidine metabolism
0.000 0.229 0.771
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.230 0.770
G36 Other acute disseminated demyelination
0.769 0.231 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.235 0.765
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.235 0.765
L40.1 Generalised pustular psoriasis
0.000 0.235 0.765
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.235 0.764
H30-H36 Disorders of choroid and retina
0.000 0.244 0.756
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.244 0.756
E13 Other specified diabetes mellitus
0.000 0.246 0.754
C91.9 Lymphoid leukaemia, unspecified
0.000 0.247 0.753
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.247 0.753
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.247 0.753
M06.34 Rheumatoid nodule (Hand)
0.000 0.248 0.752
M06.4 Inflammatory polyarthropathy
0.000 0.248 0.752
L42 Pityriasis rosea
0.000 0.248 0.752
D04.2 Skin of ear and external auricular canal
0.000 0.249 0.751
D09.1 Other and unspecified urinary organs
0.000 0.250 0.750
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.251 0.749
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.252 0.748
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.252 0.748
D03.5 Melanoma in situ of trunk
0.000 0.257 0.743
H35 Other retinal disorders
0.000 0.257 0.743
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.259 0.741
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.259 0.741
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.261 0.739
E23.7 Disorder of pituitary gland, unspecified
0.000 0.263 0.737
C83.1 Small cleaved cell (diffuse)
0.000 0.267 0.733
E70 Disorders of aromatic amino-acid metabolism
0.000 0.267 0.733
C83.7 Burkitt's tumour
0.000 0.269 0.731
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.270 0.730
M06.8 Other specified rheumatoid arthritis
0.000 0.271 0.729
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.271 0.729
E05.8 Other thyrotoxicosis
0.000 0.272 0.728
C73 Malignant neoplasm of thyroid gland
0.000 0.272 0.728
# Top node
0.000 0.274 0.726
E84 Cystic fibrosis
0.000 0.274 0.726
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.277 0.723
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.279 0.721
E23.6 Other disorders of pituitary gland
0.000 0.282 0.718
D04.6 Skin of upper limb, including shoulder
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
D04.8 Skin of other sites
0.000 0.283 0.716
D04.0 Skin of lip
0.000 0.283 0.716
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.286 0.714
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.286 0.714
M10 Gout
0.000 0.286 0.714
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.286 0.714
E11.2 With renal complications
0.000 0.286 0.713
C44.8 Overlapping lesion of skin
0.000 0.287 0.713
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.287 0.713
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.289 0.711
C85.0 Lymphosarcoma
0.000 0.289 0.711
D06.0 Endocervix
0.000 0.290 0.710
H35.8 Other specified retinal disorders
0.000 0.291 0.709
E77 Disorders of glycoprotein metabolism
0.000 0.291 0.708
E76 Disorders of glycosaminoglycan metabolism
0.000 0.291 0.708
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.291 0.708
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.291 0.708
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.292 0.708
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.293 0.706
E28 Ovarian dysfunction
0.000 0.296 0.704
H35.6 Retinal haemorrhage
0.000 0.297 0.703
E03.1 Congenital hypothyroidism without goitre
0.000 0.297 0.703
C82.6 Cutaneous follicle centre lymphoma
0.000 0.298 0.702
C82.5 Diffuse follicle centre lymphoma
0.000 0.298 0.702
C82.4 Follicular lymphoma grade IIIb
0.000 0.298 0.702
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.298 0.701
E89.5 Postprocedural testicular hypofunction
0.000 0.298 0.701
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.301 0.699
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.301 0.699
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.302 0.698
D06.7 Other parts of cervix
0.000 0.302 0.698
D06.1 Exocervix
0.000 0.302 0.698
L43 Lichen planus
0.000 0.305 0.695
L40.3 Pustulosis palmaris et plantaris
0.000 0.305 0.694
L40.2 Acrodermatitis continua
0.000 0.305 0.694
C86 Other specified types of T/NK-cell lymphoma
0.000 0.306 0.694
C83.6 Undifferentiated (diffuse)
0.000 0.306 0.694
C83.5 Lymphoblastic (diffuse)
0.000 0.306 0.694
C83.4 Immunoblastic (diffuse)
0.000 0.306 0.694
C83.2 Mixed small and large cell (diffuse)
0.000 0.306 0.694
L40.4 Guttate psoriasis
0.000 0.307 0.693
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.307 0.693
C91.0 Acute lymphoblastic leukaemia
0.000 0.309 0.691
M11 Other crystal arthropathies
0.000 0.311 0.689
E89.1 Postprocedural hypoinsulinaemia
0.000 0.315 0.685
C93 Monocytic leukaemia
0.000 0.322 0.678
M12 Other specific arthropathies
0.000 0.322 0.678
C91.5 Adult T-cell leukaemia
0.000 0.325 0.675
D09.9 Carcinoma in situ, unspecified
0.000 0.326 0.674
D09.7 Carcinoma in situ of other specified sites
0.000 0.326 0.674
D09.3 Thyroid and other endocrine glands
0.000 0.326 0.674
D09.2 Eye
0.000 0.326 0.674
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.326 0.674
C88 Malignant immunoproliferative diseases
0.000 0.327 0.673
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.327 0.673
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.327 0.673
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.327 0.673
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.327 0.673
H35.2 Other proliferative retinopathy
0.000 0.327 0.673
E88.8 Other specified metabolic disorders
0.000 0.327 0.673
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.327 0.672
E11.8 With unspecified complications
0.000 0.327 0.672
D07.2 Vagina
0.000 0.328 0.672
C94 Other leukaemias of specified cell type
0.000 0.329 0.671
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.332 0.668
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.338 0.662
C82.3 Follicular lymphoma grade IIIa
0.000 0.339 0.661
Chapter VII Diseases of the eye and adnexa
0.000 0.340 0.660
L44 Other papulosquamous disorders
0.000 0.340 0.660
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.340 0.660
E73 Lactose intolerance
0.000 0.342 0.658
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.342 0.658
D00.1 Oesophagus
0.000 0.343 0.657
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.344 0.656
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.344 0.656
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.344 0.656
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.345 0.655
M06.38 Rheumatoid nodule (Other)
0.000 0.345 0.655
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.345 0.655
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.345 0.655
M06.33 Rheumatoid nodule (Forearm)
0.000 0.345 0.655
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.345 0.655
D04.1 Skin of eyelid, including canthus
0.000 0.345 0.655
L57.5 Actinic granuloma
0.000 0.345 0.654
L57.3 Poikiloderma of Civatte
0.000 0.345 0.654
L57.2 Cutis rhomboidalis nuchae
0.000 0.345 0.654
L57.1 Actinic reticuloid
0.000 0.345 0.654
C12 Malignant neoplasm of pyriform sinus
0.000 0.347 0.653
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.349 0.651
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.350 0.649
E32 Diseases of thymus
0.000 0.350 0.649
E31 Polyglandular dysfunction
0.000 0.350 0.649
E30 Disorders of puberty, not elsewhere classified
0.000 0.350 0.649
E78.8 Other disorders of lipoprotein metabolism
0.000 0.352 0.648
E16.1 Other hypoglycaemia
0.000 0.354 0.646
L41 Parapsoriasis
0.000 0.356 0.644
E03.8 Other specified hypothyroidism
0.000 0.357 0.643
E88.9 Metabolic disorder, unspecified
0.000 0.359 0.641
M05.2 Rheumatoid vasculitis
0.000 0.364 0.636
E29 Testicular dysfunction
0.000 0.366 0.634
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.366 0.634
L55 Sunburn
0.000 0.367 0.633
E85 Amyloidosis
0.000 0.367 0.633
E23.2 Diabetes insipidus
0.000 0.368 0.632
H30 Chorioretinal inflammation
0.000 0.369 0.631
D07.4 Penis
0.000 0.369 0.631
D00.0 Lip, oral cavity and pharynx
0.000 0.370 0.630
D02.0 Larynx
0.000 0.370 0.630
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.370 0.630
D03.4 Melanoma in situ of scalp and neck
0.000 0.372 0.628
L40.0 Psoriasis vulgaris
0.000 0.372 0.628
E15 Nondiabetic hypoglycaemic coma
0.000 0.373 0.627
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.373 0.627
C91.4 Hairy-cell leukaemia
0.000 0.373 0.627
D03.3 Melanoma in situ of other and unspecified parts of face
0.000 0.374 0.626
E20 Hypoparathyroidism
0.000 0.374 0.626
E06.5 Other chronic thyroiditis
0.000 0.376 0.624
E27.5 Adrenomedullary hyperfunction
0.000 0.378 0.622
E27.0 Other adrenocortical overactivity
0.000 0.378 0.622
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.379 0.621
M14 Arthropathies in other diseases classified elsewhere
0.000 0.379 0.620
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.380 0.619
E24 Cushing's syndrome
0.000 0.384 0.616
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.384 0.615
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.385 0.615
C91.7 Other lymphoid leukaemia
0.000 0.385 0.615
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.385 0.615
C91.3 Prolymphocytic leukaemia
0.000 0.385 0.615
C91.2 Subacute lymphocytic leukaemia
0.000 0.385 0.615
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.388 0.612
C95 Leukaemia of unspecified cell type
0.000 0.389 0.611
E06.4 Drug-induced thyroiditis
0.000 0.392 0.608
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.392 0.608
E06.0 Acute thyroiditis
0.000 0.392 0.608
C43.8 Overlapping malignant melanoma of skin
0.000 0.392 0.608
C43.0 Malignant melanoma of lip
0.000 0.392 0.608
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.394 0.606
G36.0 Neuromyelitis optica [Devic]
0.606 0.394 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.395 0.605
D03.9 Melanoma in situ, unspecified
0.000 0.395 0.605
D03.8 Melanoma in situ of other sites
0.000 0.395 0.605
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.397 0.603
E26 Hyperaldosteronism
0.000 0.398 0.602
E78.3 Hyperchylomicronaemia
0.000 0.398 0.601
E11.6 With other specified complications
0.000 0.402 0.598
L58 Radiodermatitis
0.000 0.403 0.597
E83 Disorders of mineral metabolism
0.044 0.404 0.552
E25 Adrenogenital disorders
0.000 0.404 0.596
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.404 0.596
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.404 0.595
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.409 0.591
E23.1 Drug-induced hypopituitarism
0.000 0.409 0.591
C71 Malignant neoplasm of brain
0.000 0.412 0.588
E80.1 Porphyria cutanea tarda
0.000 0.413 0.587
D07.1 Vulva
0.000 0.413 0.587
D00.2 Stomach
0.000 0.413 0.586
D03.0 Melanoma in situ of lip
0.000 0.413 0.586
E88.3 Tumour lysis syndrome
0.000 0.414 0.586
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.414 0.586
L57.4 Cutis laxa senilis
0.000 0.414 0.585
E80.4 Gilbert's syndrome
0.000 0.416 0.584
D01.0 Colon
0.000 0.417 0.583
C81 Hodgkin's disease
0.000 0.418 0.582
E72 Other disorders of amino-acid metabolism
0.000 0.418 0.582
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.419 0.581
C03 Malignant neoplasm of gum
0.000 0.419 0.581
E13.9 Without complications
0.000 0.422 0.578
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.422 0.578
L43.8 Other lichen planus
0.000 0.423 0.577
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.424 0.576
M13 Other arthritis
0.000 0.425 0.575
E27.9 Disorder of adrenal gland, unspecified
0.000 0.427 0.573
M10.0 Idiopathic gout
0.000 0.428 0.572
E40-E46 Malnutrition
0.000 0.429 0.571
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.434 0.566
C13 Malignant neoplasm of hypopharynx
0.000 0.436 0.564
E88.2 Lipomatosis, not elsewhere classified
0.000 0.436 0.564
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.437 0.563
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.437 0.563
E16.4 Abnormal secretion of gastrin
0.000 0.437 0.563
E16.3 Increased secretion of glucagon
0.000 0.437 0.563
D02.4 Respiratory system, unspecified
0.000 0.437 0.562
D02.3 Other parts of respiratory system
0.000 0.437 0.562
D02.2 Bronchus and lung
0.000 0.437 0.562
D02.1 Trachea
0.000 0.437 0.562
M11.9 Crystal arthropathy, unspecified
0.000 0.438 0.562
H35.0 Background retinopathy and retinal vascular changes
0.000 0.438 0.562
C43.4 Malignant melanoma of scalp and neck
0.000 0.439 0.561
D01.3 Anus and anal canal
0.000 0.440 0.560
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.440 0.560
E07 Other disorders of thyroid
0.000 0.440 0.560
C11 Malignant neoplasm of nasopharynx
0.000 0.442 0.558
E14 Unspecified diabetes mellitus
0.000 0.442 0.558
H53-H54 Visual disturbances and blindness
0.000 0.443 0.556
C74 Malignant neoplasm of adrenal gland
0.000 0.445 0.555
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.447 0.553
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.447 0.553
E79.1 Lesch-Nyhan syndrome
0.000 0.447 0.553
C44.2 Skin of ear and external auricular canal
0.000 0.448 0.552
G36.9 Acute disseminated demyelination, unspecified
0.551 0.448 0.000
G36.8 Other specified acute disseminated demyelination
0.551 0.448 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.551 0.448 0.000
E27.2 Addisonian crisis
0.000 0.449 0.551
E70.3 Albinism
0.000 0.449 0.551
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.449 0.550
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.450 0.550
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.451 0.549
D07.6 Other and unspecified male genital organs
0.000 0.452 0.548
D07.3 Other and unspecified female genital organs
0.000 0.452 0.548
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.452 0.548
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.453 0.547
L10-L14 Bullous disorders
0.000 0.454 0.546
E27.8 Other specified disorders of adrenal gland
0.000 0.455 0.545
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.457 0.543
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.458 0.542
H30.9 Chorioretinal inflammation, unspecified
0.000 0.458 0.542
E13.8 With unspecified complications
0.000 0.459 0.541
E13.7 With multiple complications
0.000 0.459 0.541
E13.6 With other specified complications
0.000 0.459 0.541
E13.5 With peripheral circulatory complications
0.000 0.459 0.541
E13.4 With neurological complications
0.000 0.459 0.541
E13.3 With ophthalmic complications
0.000 0.459 0.541
E13.2 With renal complications
0.000 0.459 0.541
E13.1 With ketoacidosis
0.000 0.459 0.541
E13.0 With coma
0.000 0.459 0.541
C02.9 Tongue, unspecified
0.000 0.460 0.540
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.461 0.539
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.461 0.539
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.461 0.539
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.461 0.539
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.461 0.539
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.461 0.539
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.461 0.539
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.461 0.539
E28.2 Polycystic ovarian syndrome
0.000 0.462 0.538
E84.9 Cystic fibrosis, unspecified
0.000 0.462 0.537
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.463 0.536
E80.5 Crigler-Najjar syndrome
0.000 0.463 0.536
E80.3 Defects of catalase and peroxydase
0.000 0.463 0.536
E80.0 Hereditary erythropoietic porphyria
0.000 0.463 0.536
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.465 0.535
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.466 0.534
H53 Visual disturbances
0.000 0.466 0.534
H35.1 Retinopathy of prematurity
0.000 0.467 0.533
C07 Malignant neoplasm of parotid gland
0.000 0.469 0.531
E28.3 Primary ovarian failure
0.000 0.470 0.530
D01.9 Digestive organ, unspecified
0.000 0.470 0.530
D01.7 Other specified digestive organs
0.000 0.470 0.530
D01.5 Liver, gallbladder and bile ducts
0.000 0.470 0.530
D01.4 Other and unspecified parts of intestine
0.000 0.470 0.530
D01.1 Rectosigmoid junction
0.000 0.470 0.530
D03.6 Melanoma in situ of upper limb, including shoulder
0.000 0.470 0.530
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.471 0.529
C05 Malignant neoplasm of palate
0.000 0.473 0.527
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.474 0.526
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.474 0.526
E70.2 Disorders of tyrosine metabolism
0.000 0.474 0.526
E70.1 Other hyperphenylalaninaemias
0.000 0.474 0.526
E70.0 Classical phenylketonuria
0.000 0.474 0.526
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.477 0.522
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.477 0.522
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.477 0.522
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.477 0.522
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.477 0.522
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.477 0.522
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.477 0.522
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.477 0.522
E16.2 Hypoglycaemia, unspecified
0.000 0.478 0.522
E78.4 Other hyperlipidaemia
0.000 0.478 0.522
E80.6 Other disorders of bilirubin metabolism
0.000 0.478 0.521
C71.0 Cerebrum, except lobes and ventricles
0.000 0.478 0.521
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.479 0.521
E84.8 Cystic fibrosis with other manifestations
0.000 0.480 0.520
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.480 0.520
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.480 0.520
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.480 0.520
C70 Malignant neoplasm of meninges
0.000 0.484 0.516
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.485 0.515
H35.3 Degeneration of macula and posterior pole
0.000 0.485 0.515
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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