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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857201
log Bayes Factor = 49.0482
Chromosome 6   position 32,745,156  (GRCh37) Explore rs2857201 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L57.0 Actinic keratosis
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
C44.6 Skin of upper limb, including shoulder
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E20-E35 Disorders of other endocrine glands
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.005 0.995
C44.3 Skin of other and unspecified parts of face
0.000 0.005 0.995
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
G35-G37 Demyelinating diseases of the central nervous system
0.992 0.008 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.009 0.991
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.011 0.989
G37 Other demyelinating diseases of central nervous system
0.989 0.011 0.000
E83.1 Disorders of iron metabolism
0.988 0.011 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.013 0.987
E10.9 Without complications
0.000 0.015 0.985
G37.9 Demyelinating disease of central nervous system, unspecified
0.984 0.016 0.000
E70-E90 Metabolic disorders
0.000 0.020 0.980
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.021 0.979
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.021 0.979
L40-L45 Papulosquamous disorders
0.000 0.031 0.969
E78.0 Pure hypercholesterolaemia
0.000 0.034 0.966
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.049 0.951
E11 Non-insulin-dependent diabetes mellitus
0.000 0.051 0.949
E27 Other disorders of adrenal gland
0.000 0.065 0.935
C44.4 Skin of scalp and neck
0.000 0.069 0.931
E23.6 Other disorders of pituitary gland
0.000 0.071 0.929
E23.7 Disorder of pituitary gland, unspecified
0.000 0.076 0.924
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.078 0.922
E11.3 With ophthalmic complications
0.000 0.087 0.913
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.092 0.908
C44.2 Skin of ear and external auricular canal
0.000 0.096 0.904
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.100 0.900
E78.5 Hyperlipidaemia, unspecified
0.000 0.109 0.891
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.114 0.886
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.116 0.884
G37.8 Other specified demyelinating diseases of central nervous system
0.883 0.117 0.000
C44.0 Skin of lip
0.000 0.119 0.881
E10.5 With peripheral circulatory complications
0.000 0.120 0.880
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.121 0.879
E27.1 Primary adrenocortical insufficiency
0.000 0.122 0.878
L43 Lichen planus
0.000 0.128 0.872
E10.1 With ketoacidosis
0.000 0.143 0.857
E89.0 Postprocedural hypothyroidism
0.000 0.153 0.847
E11.9 Without complications
0.000 0.156 0.844
E78.2 Mixed hyperlipidaemia
0.000 0.156 0.844
E23.2 Diabetes insipidus
0.000 0.161 0.839
E10.0 With coma
0.000 0.162 0.838
M06.0 Seronegative rheumatoid arthritis
0.000 0.163 0.837
E06 Thyroiditis
0.000 0.164 0.836
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.167 0.833
E78.6 Lipoprotein deficiency
0.000 0.174 0.826
L40.1 Generalised pustular psoriasis
0.000 0.175 0.825
M06.3 Rheumatoid nodule
0.000 0.176 0.824
E04 Other non-toxic goitre
0.000 0.188 0.812
E28 Ovarian dysfunction
0.000 0.189 0.811
M10 Gout
0.000 0.196 0.804
E78.1 Pure hyperglyceridaemia
0.000 0.196 0.804
G36 Other acute disseminated demyelination
0.804 0.196 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.196 0.804
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.198 0.802
L40.0 Psoriasis vulgaris
0.000 0.200 0.800
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.214 0.786
E10.2 With renal complications
0.000 0.215 0.785
E88 Other metabolic disorders
0.000 0.216 0.784
E29 Testicular dysfunction
0.000 0.216 0.784
E11.2 With renal complications
0.000 0.223 0.777
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.223 0.777
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.225 0.775
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.227 0.773
E13 Other specified diabetes mellitus
0.000 0.229 0.771
E06.3 Autoimmune thyroiditis
0.000 0.231 0.769
M06.4 Inflammatory polyarthropathy
0.000 0.233 0.767
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.239 0.761
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.246 0.754
L43.9 Lichen planus, unspecified
0.000 0.250 0.750
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.252 0.748
E24 Cushing's syndrome
0.000 0.253 0.747
E23.0 Hypopituitarism
0.000 0.258 0.742
E84 Cystic fibrosis
0.000 0.260 0.740
E26 Hyperaldosteronism
0.000 0.261 0.738
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.264 0.736
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.264 0.736
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.265 0.735
E10.8 With unspecified complications
0.000 0.266 0.734
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.267 0.733
L43.8 Other lichen planus
0.000 0.268 0.732
L40.4 Guttate psoriasis
0.000 0.270 0.730
E04.0 Non-toxic diffuse goitre
0.000 0.273 0.727
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.275 0.725
L42 Pityriasis rosea
0.000 0.279 0.721
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
E79 Disorders of purine and pyrimidine metabolism
0.000 0.285 0.715
E11.1 With ketoacidosis
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E10.6 With other specified complications
0.000 0.287 0.713
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.288 0.712
G37.5 Concentric sclerosis [Balo]
0.709 0.291 0.000
G37.4 Subacute necrotising myelitis
0.709 0.291 0.000
G37.2 Central pontine myelinolysis
0.709 0.291 0.000
G37.1 Central demyelination of corpus callosum
0.709 0.291 0.000
G37.0 Diffuse sclerosis
0.709 0.291 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.292 0.708
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.292 0.708
E23.1 Drug-induced hypopituitarism
0.000 0.292 0.708
E05.8 Other thyrotoxicosis
0.000 0.292 0.708
E77 Disorders of glycoprotein metabolism
0.000 0.298 0.702
E76 Disorders of glycosaminoglycan metabolism
0.000 0.298 0.702
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.298 0.702
E70 Disorders of aromatic amino-acid metabolism
0.000 0.298 0.702
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.298 0.702
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.301 0.698
L44 Other papulosquamous disorders
0.000 0.305 0.695
L41 Parapsoriasis
0.000 0.305 0.695
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.305 0.695
E11.0 With coma
0.000 0.307 0.692
M06.8 Other specified rheumatoid arthritis
0.000 0.309 0.691
E11.8 With unspecified complications
0.000 0.311 0.689
E27.9 Disorder of adrenal gland, unspecified
0.000 0.313 0.687
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.313 0.687
E03.8 Other specified hypothyroidism
0.000 0.314 0.686
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.316 0.684
E28.2 Polycystic ovarian syndrome
0.000 0.317 0.683
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.318 0.682
E03.1 Congenital hypothyroidism without goitre
0.000 0.318 0.682
L57.5 Actinic granuloma
0.000 0.318 0.682
L57.3 Poikiloderma of Civatte
0.000 0.318 0.682
L57.2 Cutis rhomboidalis nuchae
0.000 0.318 0.682
L57.1 Actinic reticuloid
0.000 0.318 0.682
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.319 0.681
E11.7 With multiple complications
0.000 0.319 0.681
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.322 0.677
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.323 0.677
E20 Hypoparathyroidism
0.000 0.323 0.677
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.325 0.675
E89.4 Postprocedural ovarian failure
0.000 0.326 0.674
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.329 0.671
E27.5 Adrenomedullary hyperfunction
0.000 0.330 0.670
E27.0 Other adrenocortical overactivity
0.000 0.330 0.670
G36.0 Neuromyelitis optica [Devic]
0.669 0.331 0.000
E78.4 Other hyperlipidaemia
0.000 0.332 0.668
M12 Other specific arthropathies
0.000 0.334 0.666
E80.4 Gilbert's syndrome
0.000 0.337 0.663
E10.4 With neurological complications
0.000 0.338 0.662
L55 Sunburn
0.000 0.339 0.661
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.656 0.343 0.000
E25 Adrenogenital disorders
0.000 0.344 0.656
M06.34 Rheumatoid nodule (Hand)
0.000 0.346 0.654
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.347 0.653
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.349 0.651
E89.5 Postprocedural testicular hypofunction
0.000 0.349 0.651
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.350 0.650
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.353 0.647
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.357 0.643
L82 Seborrhoeic keratosis
0.000 0.361 0.639
E88.8 Other specified metabolic disorders
0.000 0.361 0.639
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.362 0.638
M10.0 Idiopathic gout
0.000 0.362 0.638
E04.2 Non-toxic multinodular goitre
0.000 0.365 0.635
E29.1 Testicular hypofunction
0.000 0.368 0.632
M05.2 Rheumatoid vasculitis
0.000 0.370 0.629
D00-D09 In situ neoplasms
0.000 0.370 0.630
E89.1 Postprocedural hypoinsulinaemia
0.000 0.372 0.628
E04.9 Non-toxic goitre, unspecified
0.000 0.374 0.626
L43.3 Subacute (active) lichen planus
0.000 0.375 0.625
L43.2 Lichenoid drug reaction
0.000 0.375 0.625
L43.1 Bullous lichen planus
0.000 0.375 0.625
L43.0 Hypertrophic lichen planus
0.000 0.375 0.625
M10.9 Gout, unspecified
0.000 0.375 0.625
E78.3 Hyperchylomicronaemia
0.000 0.376 0.624
E89.2 Postprocedural hypoparathyroidism
0.000 0.376 0.624
D04 Carcinoma in situ of skin
0.000 0.377 0.623
Chapter II Neoplasms
0.000 0.377 0.623
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.378 0.622
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.379 0.621
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.379 0.621
M11 Other crystal arthropathies
0.000 0.380 0.620
E27.8 Other specified disorders of adrenal gland
0.000 0.380 0.620
D06 Carcinoma in situ of cervix uteri
0.000 0.381 0.619
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.385 0.615
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.385 0.615
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.386 0.614
D06.9 Cervix, unspecified
0.000 0.388 0.612
E11.6 With other specified complications
0.000 0.389 0.611
E74 Other disorders of carbohydrate metabolism
0.000 0.392 0.607
E13.9 Without complications
0.000 0.393 0.607
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.393 0.607
L58 Radiodermatitis
0.000 0.394 0.606
E72 Other disorders of amino-acid metabolism
0.000 0.398 0.601
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.400 0.600
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.400 0.600
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.400 0.600
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.400 0.600
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.400 0.600
E06.5 Other chronic thyroiditis
0.000 0.400 0.599
E06.4 Drug-induced thyroiditis
0.000 0.400 0.599
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.400 0.599
E06.0 Acute thyroiditis
0.000 0.400 0.599
E88.2 Lipomatosis, not elsewhere classified
0.000 0.401 0.599
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.402 0.598
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.402 0.597
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.404 0.596
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.404 0.596
E88.9 Metabolic disorder, unspecified
0.000 0.404 0.595
E73 Lactose intolerance
0.000 0.405 0.594
L85 Other epidermal thickening
0.000 0.407 0.593
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.409 0.591
M06.38 Rheumatoid nodule (Other)
0.000 0.409 0.591
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.409 0.591
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.409 0.591
M06.33 Rheumatoid nodule (Forearm)
0.000 0.409 0.591
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.409 0.591
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.409 0.591
E21.3 Hyperparathyroidism, unspecified
0.000 0.409 0.591
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.409 0.591
E85 Amyloidosis
0.000 0.415 0.584
E04.8 Other specified non-toxic goitre
0.000 0.418 0.582
E28.9 Ovarian dysfunction, unspecified
0.000 0.419 0.581
E28.8 Other ovarian dysfunction
0.000 0.419 0.581
E28.1 Androgen excess
0.000 0.419 0.581
E28.0 Oestrogen excess
0.000 0.419 0.581
E06.9 Thyroiditis, unspecified
0.000 0.420 0.580
L94 Other localised connective tissue disorders
0.000 0.422 0.578
C83.3 Large cell (diffuse)
0.000 0.423 0.577
M10.4 Other secondary gout
0.000 0.423 0.577
M10.2 Drug-induced gout
0.000 0.423 0.577
M10.1 Lead-induced gout
0.000 0.423 0.577
G36.9 Acute disseminated demyelination, unspecified
0.576 0.424 0.000
G36.8 Other specified acute disseminated demyelination
0.576 0.424 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.576 0.424 0.000
L10-L14 Bullous disorders
0.000 0.424 0.576
E28.3 Primary ovarian failure
0.000 0.427 0.573
D04.5 Skin of trunk
0.000 0.428 0.572
L85.8 Other specified epidermal thickening
0.000 0.428 0.572
E80.1 Porphyria cutanea tarda
0.000 0.429 0.570
E84.9 Cystic fibrosis, unspecified
0.000 0.432 0.568
E80.6 Other disorders of bilirubin metabolism
0.000 0.434 0.566
M14 Arthropathies in other diseases classified elsewhere
0.000 0.435 0.565
E88.3 Tumour lysis syndrome
0.000 0.437 0.562
L57.4 Cutis laxa senilis
0.000 0.438 0.562
E29.9 Testicular dysfunction, unspecified
0.000 0.438 0.562
E29.8 Other testicular dysfunction
0.000 0.438 0.562
E29.0 Testicular hyperfunction
0.000 0.438 0.562
D04.3 Skin of other and unspecified parts of face
0.000 0.439 0.561
M10.3 Gout due to impairment of renal function
0.000 0.440 0.560
E24.0 Pituitary-dependent Cushing's disease
0.000 0.440 0.560
E21.0 Primary hyperparathyroidism
0.000 0.443 0.557
E21.4 Other specified disorders of parathyroid gland
0.000 0.444 0.556
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.445 0.555
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.445 0.554
E80.5 Crigler-Najjar syndrome
0.000 0.445 0.554
E80.3 Defects of catalase and peroxydase
0.000 0.445 0.554
E80.0 Hereditary erythropoietic porphyria
0.000 0.445 0.554
E26.0 Primary hyperaldosteronism
0.000 0.446 0.554
E27.2 Addisonian crisis
0.000 0.446 0.554
E13.8 With unspecified complications
0.000 0.447 0.553
E13.7 With multiple complications
0.000 0.447 0.553
E13.6 With other specified complications
0.000 0.447 0.553
E13.5 With peripheral circulatory complications
0.000 0.447 0.553
E13.4 With neurological complications
0.000 0.447 0.553
E13.3 With ophthalmic complications
0.000 0.447 0.553
E13.2 With renal complications
0.000 0.447 0.553
E13.1 With ketoacidosis
0.000 0.447 0.553
E13.0 With coma
0.000 0.447 0.553
M13 Other arthritis
0.000 0.448 0.552
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.450 0.550
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.450 0.550
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.450 0.550
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.450 0.550
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.450 0.550
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.450 0.550
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.450 0.550
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.450 0.550
C43 Malignant melanoma of skin
0.000 0.450 0.550
E11.5 With peripheral circulatory complications
0.000 0.454 0.546
M10.90 Gout, unspecified (Multiple sites)
0.000 0.454 0.546
E24.9 Cushing's syndrome, unspecified
0.000 0.458 0.542
E21.2 Other hyperparathyroidism
0.000 0.458 0.542
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.460 0.540
E78.8 Other disorders of lipoprotein metabolism
0.000 0.461 0.539
E24.2 Drug-induced Cushing's syndrome
0.000 0.462 0.538
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.462 0.538
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.463 0.537
E24.8 Other Cushing's syndrome
0.000 0.465 0.535
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.465 0.535
E24.3 Ectopic ACTH syndrome
0.000 0.465 0.535
E24.1 Nelson's syndrome
0.000 0.465 0.535
D04.7 Skin of lower limb, including hip
0.000 0.466 0.534
C85.1 B-cell lymphoma, unspecified
0.000 0.466 0.534
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.469 0.531
E84.8 Cystic fibrosis with other manifestations
0.000 0.469 0.530
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.469 0.530
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.469 0.530
E26.9 Hyperaldosteronism, unspecified
0.000 0.470 0.529
E26.8 Other hyperaldosteronism
0.000 0.470 0.529
E26.1 Secondary hyperaldosteronism
0.000 0.470 0.529
L56.3 Solar urticaria
0.000 0.472 0.528
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.472 0.528
L56.1 Drug photoallergic response
0.000 0.472 0.528
L56.0 Drug phototoxic response
0.000 0.472 0.528
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.472 0.528
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.475 0.525
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.476 0.524
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.476 0.524
C73 Malignant neoplasm of thyroid gland
0.000 0.477 0.523
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.479 0.521
E40-E46 Malnutrition
0.000 0.479 0.521
M10.09 Idiopathic gout (Site unspecified)
0.000 0.481 0.518
L94.2 Calcinosis cutis
0.000 0.483 0.517
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.485 0.515
D09 Carcinoma in situ of other and unspecified sites
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.514
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.486 0.514
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.486 0.514
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.486 0.514
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.486 0.514
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.486 0.514
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.486 0.514
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.486 0.514
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.486 0.514
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.486 0.514
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.486 0.514
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.486 0.514
M07.18 Arthritis mutilans (Other)
0.000 0.486 0.514
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.486 0.514
M07.16 Arthritis mutilans (Lower leg)
0.000 0.486 0.514
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.486 0.514
M07.14 Arthritis mutilans (Hand)
0.000 0.486 0.514
M07.13 Arthritis mutilans (Forearm)
0.000 0.486 0.514
M07.12 Arthritis mutilans (Upper arm)
0.000 0.486 0.514
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.486 0.514
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.486 0.514
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.486 0.514
M07.28 Psoriatic spondylitis (Other)
0.000 0.486 0.514
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.486 0.514
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.486 0.514
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.486 0.514
M07.24 Psoriatic spondylitis (Hand)
0.000 0.486 0.514
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.486 0.514
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.486 0.514
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.486 0.514
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.486 0.514
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.486 0.514
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.486 0.514
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.486 0.514
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.486 0.514
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.486 0.514
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.486 0.514
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.486 0.514
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.486 0.514
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.486 0.514
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.486 0.514
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.486 0.514
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.486 0.514
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.486 0.514
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.486 0.514
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.000 0.486 0.514
M07.54 Arthropathy in ulcerative colitis (Hand)
0.000 0.486 0.514
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.000 0.486 0.514
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.000 0.486 0.514
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.000 0.486 0.514
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.000 0.486 0.514
M07.69 Other enteropathic arthropathies (Site unspecified)
0.000 0.486 0.514
M07.68 Other enteropathic arthropathies (Other)
0.000 0.486 0.514
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.000 0.486 0.514
M07.66 Other enteropathic arthropathies (Lower leg)
0.000 0.486 0.514
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.000 0.486 0.514
M07.64 Other enteropathic arthropathies (Hand)
0.000 0.486 0.514
M07.63 Other enteropathic arthropathies (Forearm)
0.000 0.486 0.514
M07.62 Other enteropathic arthropathies (Upper arm)
0.000 0.486 0.514
M07.61 Other enteropathic arthropathies (Shoulder region)
0.000 0.486 0.514
M07.60 Other enteropathic arthropathies (Multiple sites)
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.000 0.486 0.514
M05.08 Felty's syndrome (Other)
0.000 0.486 0.514
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.486 0.514
M05.06 Felty's syndrome (Lower leg)
0.000 0.486 0.514
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.486 0.514
M05.04 Felty's syndrome (Hand)
0.000 0.486 0.514
M05.03 Felty's syndrome (Forearm)
0.000 0.486 0.514
M05.02 Felty's syndrome (Upper arm)
0.000 0.486 0.514
M05.01 Felty's syndrome (Shoulder region)
0.000 0.486 0.514
M05.00 Felty's syndrome (Multiple sites)
0.000 0.486 0.514
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.486 0.514
M05.18 Rheumatoid lung disease (Other)
0.000 0.486 0.514
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.486 0.514
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.486 0.514
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.486 0.514
M05.14 Rheumatoid lung disease (Hand)
0.000 0.486 0.514
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.486 0.514
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.486 0.514
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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