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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2858870
log Bayes Factor = 95.1726
Chromosome 6   position 32,572,251  (GRCh37) Explore rs2858870 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M20-M25 Other joint disorders
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
J30-J39 Other diseases of upper respiratory tract
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.001 0.999
M35.0 Sicca syndrome [Sjogren]
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
J33.0 Polyp of nasal cavity
0.000 0.002 0.998
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.003 0.997
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.003 0.997
D50-D53 Nutritional anaemias
0.000 0.004 0.996
G35 Multiple sclerosis
0.000 0.007 0.993
L20-L30 Dermatitis and eczema
0.000 0.008 0.992
D50 Iron deficiency anaemia
0.000 0.009 0.991
J20-J22 Other acute lower respiratory infections
0.000 0.009 0.991
M34 Systemic sclerosis
0.000 0.010 0.990
N48 Other disorders of penis
0.987 0.013 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.013 0.987
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.016 0.984
D50.8 Other iron deficiency anaemias
0.000 0.018 0.982
N48.6 Balanitis xerotica obliterans
0.981 0.019 0.000
J22 Unspecified acute lower respiratory infection
0.000 0.019 0.981
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.019 0.981
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.023 0.977
J84 Other interstitial pulmonary diseases
0.000 0.023 0.977
H04 Disorders of lachrymal system
0.000 0.025 0.975
L30 Other dermatitis
0.000 0.031 0.969
H55-H59 Other disorders of eye and adnexa
0.000 0.032 0.968
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.033 0.967
L40.0 Psoriasis vulgaris
0.964 0.036 0.000
L85 Other epidermal thickening
0.000 0.037 0.963
J80 Adult respiratory distress syndrome
0.000 0.037 0.963
E10.4 With neurological complications
0.000 0.038 0.962
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.043 0.957
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.045 0.955
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.046 0.954
M34.9 Systemic sclerosis, unspecified
0.000 0.050 0.950
M06.0 Seronegative rheumatoid arthritis
0.000 0.053 0.947
L85.9 Epidermal thickening, unspecified
0.000 0.054 0.946
D68 Other coagulation defects
0.000 0.055 0.945
H57 Other disorders of eye and adnexa
0.000 0.056 0.944
N40-N51 Diseases of male genital organs
0.944 0.056 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.058 0.942
N47 Redundant prepuce, phimosis and paraphimosis
0.940 0.060 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.062 0.938
E10.2 With renal complications
0.000 0.066 0.934
L30.9 Dermatitis, unspecified
0.000 0.066 0.934
J32 Chronic sinusitis
0.000 0.070 0.930
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.070 0.930
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.071 0.929
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.072 0.928
E10.5 With peripheral circulatory complications
0.000 0.073 0.927
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.074 0.926
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.076 0.924
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.076 0.924
N48.8 Other specified disorders of penis
0.922 0.078 0.000
L81 Other disorders of pigmentation
0.000 0.080 0.920
E20-E35 Disorders of other endocrine glands
0.000 0.084 0.916
J31.0 Chronic rhinitis
0.000 0.084 0.916
N48.4 Impotence of organic origin
0.914 0.086 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.090 0.910
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.092 0.908
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.095 0.905
H02 Other disorders of eyelid
0.000 0.101 0.899
E06 Thyroiditis
0.000 0.101 0.899
N45 Orchitis and epididymitis
0.898 0.102 0.000
M34.1 CR(E)ST syndrome
0.000 0.102 0.898
H57.0 Anomalies of pupillary function
0.000 0.102 0.898
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.103 0.897
E27 Other disorders of adrenal gland
0.000 0.114 0.886
L81.4 Other melanin hyperpigmentation
0.000 0.118 0.882
J95-J99 Other diseases of the respiratory system
0.000 0.119 0.881
D69 Purpura and other haemorrhagic conditions
0.000 0.120 0.880
E07 Other disorders of thyroid
0.000 0.121 0.879
N48.1 Balanoposthitis
0.879 0.121 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.121 0.879
N48.9 Disorder of penis, unspecified
0.878 0.122 0.000
M35.1 Other overlap syndromes
0.000 0.122 0.878
H02.0 Entropion and trichiasis of eyelid
0.000 0.123 0.877
N48.0 Leukoplakia of penis
0.875 0.125 0.000
H06.2 Dysthyroid exophthalmos
0.000 0.126 0.874
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.126 0.874
M06.4 Inflammatory polyarthropathy
0.000 0.127 0.873
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.128 0.872
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.872 0.128 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.133 0.867
H02.1 Ectropion of eyelid
0.000 0.138 0.862
D52 Folate deficiency anaemia
0.000 0.145 0.855
L83 Acanthosis nigricans
0.000 0.145 0.855
D68.8 Other specified coagulation defects
0.000 0.146 0.854
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.150 0.850
L29 Pruritus
0.000 0.152 0.848
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.154 0.846
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.154 0.846
M06.3 Rheumatoid nodule
0.000 0.157 0.843
J81 Pulmonary oedema
0.000 0.159 0.841
Chapter VI Diseases of the nervous system
0.000 0.161 0.839
D68.5 Primary Thrombophilia
0.000 0.162 0.838
H05 Disorders of orbit
0.000 0.163 0.837
J33.8 Other polyp of sinus
0.000 0.163 0.837
L94 Other localised connective tissue disorders
0.000 0.164 0.836
L30.8 Other specified dermatitis
0.000 0.164 0.836
M34.8 Other forms of systemic sclerosis
0.000 0.165 0.835
D68.9 Coagulation defect, unspecified
0.000 0.166 0.834
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.170 0.830
L21 Seborrhoeic dermatitis
0.000 0.171 0.829
J32.0 Chronic maxillary sinusitis
0.000 0.171 0.829
H16 Keratitis
0.000 0.171 0.829
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.172 0.828
E06.3 Autoimmune thyroiditis
0.000 0.177 0.823
E04 Other non-toxic goitre
0.000 0.179 0.821
L93 Lupus erythematosus
0.000 0.184 0.816
M32 Systemic lupus erythematosus
0.000 0.189 0.811
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.190 0.810
H04.8 Other disorders of lachrymal system
0.000 0.190 0.810
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.192 0.808
E10.8 With unspecified complications
0.000 0.195 0.805
J32.9 Chronic sinusitis, unspecified
0.000 0.195 0.805
H57.9 Disorder of eye and adnexa, unspecified
0.000 0.199 0.801
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.202 0.798
L27 Dermatitis due to substances taken internally
0.000 0.205 0.795
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.205 0.795
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.206 0.794
N48.2 Other inflammatory disorders of penis
0.794 0.206 0.000
L57.0 Actinic keratosis
0.000 0.208 0.792
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.211 0.789
N48.5 Ulcer of penis
0.789 0.211 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.217 0.783
H57.8 Other specified disorders of eye and adnexa
0.000 0.219 0.781
L29.0 Pruritus ani
0.000 0.220 0.780
E07.9 Disorder of thyroid, unspecified
0.000 0.221 0.779
L40-L45 Papulosquamous disorders
0.461 0.222 0.317
H20 Iridocyclitis
0.000 0.223 0.777
H16.0 Corneal ulcer
0.000 0.223 0.777
J84.8 Other specified interstitial pulmonary diseases
0.000 0.224 0.776
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.225 0.775
L80 Vitiligo
0.000 0.229 0.771
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.230 0.770
H55 Nystagmus and other irregular eye movements
0.000 0.232 0.768
E28 Ovarian dysfunction
0.000 0.234 0.766
E05.8 Other thyrotoxicosis
0.000 0.235 0.765
J32.8 Other chronic sinusitis
0.000 0.237 0.763
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.237 0.763
D68.0 Von Willebrand's disease
0.000 0.238 0.762
D51 Vitamin B12 deficiency anaemia
0.000 0.239 0.761
J20 Acute bronchitis
0.000 0.243 0.757
M06.34 Rheumatoid nodule (Hand)
0.000 0.244 0.756
E04.2 Non-toxic multinodular goitre
0.000 0.244 0.756
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.244 0.756
D69.5 Secondary thrombocytopenia
0.000 0.245 0.755
D52.9 Folate deficiency anaemia, unspecified
0.000 0.245 0.755
H05.0 Acute inflammation of orbit
0.000 0.246 0.754
J21 Acute bronchiolitis
0.000 0.246 0.754
L82 Seborrhoeic keratosis
0.000 0.250 0.750
E20 Hypoparathyroidism
0.000 0.251 0.749
D80-D89 Certain disorders involving the immune mechanism
0.000 0.251 0.749
L40.1 Generalised pustular psoriasis
0.749 0.251 0.000
H04.1 Other disorders of lachrymal gland
0.000 0.253 0.747
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.255 0.745
L20 Atopic dermatitis
0.000 0.265 0.735
N44 Torsion of testis
0.733 0.267 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.267 0.733
L28 Lichen simplex chronicus and prurigo
0.000 0.269 0.731
E14 Unspecified diabetes mellitus
0.000 0.271 0.729
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.272 0.728
L25 Unspecified contact dermatitis
0.000 0.272 0.727
L08 Other local infections of skin and subcutaneous tissue
0.000 0.273 0.727
M00-M03 Infectious arthropathies
0.000 0.275 0.725
M60-M63 Disorders of muscles
0.000 0.276 0.724
E27.8 Other specified disorders of adrenal gland
0.000 0.276 0.724
J95.8 Other postprocedural respiratory disorders
0.000 0.277 0.723
D60-D64 Aplastic and other anaemias
0.000 0.277 0.723
H04.9 Disorder of lachrymal system, unspecified
0.000 0.278 0.721
M35.7 Hypermobility syndrome
0.000 0.281 0.719
D69.0 Allergic purpura
0.000 0.281 0.719
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.8 Other specified systemic involvement of connective tissue
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M35.2 Behcet's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
J31.2 Chronic pharyngitis
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.716
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.716
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.285 0.715
L87 Transepidermal elimination disorders
0.000 0.285 0.715
L88 Pyoderma gangrenosum
0.000 0.285 0.715
L86 Keratoderma in diseases classified elsewhere
0.000 0.285 0.715
E29 Testicular dysfunction
0.000 0.287 0.713
E03.8 Other specified hypothyroidism
0.000 0.288 0.712
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.288 0.712
L24 Irritant contact dermatitis
0.000 0.288 0.711
L26 Exfoliative dermatitis
0.000 0.288 0.711
L22 Diaper [napkin] dermatitis
0.000 0.288 0.711
H01 Other inflammation of eyelid
0.000 0.289 0.711
D50.1 Sideropenic dysphagia
0.000 0.289 0.711
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.290 0.709
M34.0 Progressive systemic sclerosis
0.000 0.290 0.709
N48.3 Priapism
0.708 0.292 0.000
H04.4 Chronic inflammation of lachrymal passages
0.000 0.293 0.707
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.297 0.703
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.297 0.703
N42 Other disorders of prostate
0.703 0.297 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.298 0.702
E10.6 With other specified complications
0.000 0.300 0.700
D67 Hereditary factor IX deficiency
0.000 0.300 0.700
J84.0 Alveolar and parietoalveolar conditions
0.000 0.300 0.700
L94.0 Localised scleroderma [morphea]
0.000 0.300 0.700
H04.6 Other changes in lachrymal passages
0.000 0.301 0.699
H04.0 Dacryoadenitis
0.000 0.301 0.699
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.302 0.698
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.302 0.698
L30.5 Pityriasis alba
0.000 0.305 0.694
L30.4 Erythema intertrigo
0.000 0.305 0.694
L30.3 Infective dermatitis
0.000 0.305 0.694
L30.2 Cutaneous autosensitisation
0.000 0.305 0.694
L30.1 Dyshidrosis [pompholyx]
0.000 0.305 0.694
L30.0 Nummular dermatitis
0.000 0.305 0.694
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.307 0.693
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.307 0.693
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.307 0.693
L98.1 Factitial dermatitis
0.000 0.307 0.693
L85.3 Xerosis cutis
0.000 0.310 0.690
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.310 0.690
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.310 0.690
L85.0 Acquired ichthyosis
0.000 0.310 0.690
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.689 0.311 0.000
J32.1 Chronic frontal sinusitis
0.000 0.311 0.689
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.312 0.688
H30 Chorioretinal inflammation
0.000 0.313 0.686
L93.0 Discoid lupus erythematosus
0.000 0.314 0.686
L58 Radiodermatitis
0.000 0.315 0.685
L55 Sunburn
0.000 0.315 0.685
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.316 0.684
J31.1 Chronic nasopharyngitis
0.000 0.316 0.684
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.321 0.679
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.321 0.679
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.321 0.679
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.321 0.679
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.321 0.679
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.321 0.679
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.321 0.679
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.321 0.679
D68.4 Acquired coagulation factor deficiency
0.000 0.322 0.678
N51 Disorders of male genital organs in diseases classified elsewhere
0.676 0.323 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.324 0.676
D68.6 Other Thrombophilia
0.000 0.325 0.675
E50-E64 Other nutritional deficiencies
0.000 0.326 0.674
H05.2 Exophthalmic conditions
0.000 0.326 0.674
E04.0 Non-toxic diffuse goitre
0.000 0.328 0.672
D68.1 Hereditary factor XI deficiency
0.000 0.328 0.672
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.330 0.670
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.330 0.670
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.332 0.668
H16.9 Keratitis, unspecified
0.000 0.332 0.668
D86 Sarcoidosis
0.000 0.332 0.668
L10-L14 Bullous disorders
0.000 0.332 0.667
J32.3 Chronic sphenoidal sinusitis
0.000 0.333 0.667
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.334 0.666
L57.5 Actinic granuloma
0.000 0.334 0.666
L57.3 Poikiloderma of Civatte
0.000 0.334 0.666
L57.2 Cutis rhomboidalis nuchae
0.000 0.334 0.666
L57.1 Actinic reticuloid
0.000 0.334 0.666
J60-J70 Lung diseases due to external agents
0.000 0.334 0.666
M45-M49 Spondylopathies
0.000 0.334 0.666
J32.4 Chronic pansinusitis
0.000 0.334 0.666
E07.8 Other specified disorders of thyroid
0.000 0.335 0.665
D50.9 Iron deficiency anaemia, unspecified
0.000 0.335 0.665
L29.2 Pruritus vulvae
0.000 0.336 0.664
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.336 0.664
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.336 0.664
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.336 0.664
M31 Other necrotising vasculopathies
0.000 0.336 0.664
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.337 0.663
D53 Other nutritional anaemias
0.000 0.338 0.662
H04.2 Epiphora
0.000 0.339 0.661
L81.7 Pigmented purpuric dermatosis
0.000 0.341 0.659
L81.6 Other disorders of diminished melanin formation
0.000 0.341 0.659
L81.5 Leukoderma, not elsewhere classified
0.000 0.341 0.659
L81.3 Cafe au lait spots
0.000 0.341 0.659
L81.2 Freckles
0.000 0.341 0.659
L81.1 Chloasma
0.000 0.341 0.659
L81.0 Postinflammatory hyperpigmentation
0.000 0.341 0.659
H20.8 Other iridocyclitis
0.000 0.342 0.658
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.343 0.657
E32 Diseases of thymus
0.000 0.343 0.657
E31 Polyglandular dysfunction
0.000 0.343 0.657
E30 Disorders of puberty, not elsewhere classified
0.000 0.343 0.657
M86-M90 Other osteopathies
0.000 0.344 0.656
M45 Ankylosing spondylitis
0.000 0.345 0.655
G37 Other demyelinating diseases of central nervous system
0.000 0.345 0.655
E06.9 Thyroiditis, unspecified
0.000 0.345 0.655
E26 Hyperaldosteronism
0.000 0.345 0.655
M30 Polyarteritis nodosa and related conditions
0.000 0.346 0.654
L94.2 Calcinosis cutis
0.000 0.347 0.653
J95.0 Tracheostomy malfunction
0.000 0.347 0.653
E14.3 With ophthalmic complications
0.000 0.350 0.650
G36 Other acute disseminated demyelination
0.000 0.351 0.648
L40.8 Other psoriasis
0.645 0.355 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.355 0.645
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.356 0.644
E06.5 Other chronic thyroiditis
0.000 0.356 0.644
E06.4 Drug-induced thyroiditis
0.000 0.356 0.644
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.356 0.644
E06.1 Subacute thyroiditis
0.000 0.356 0.644
E06.0 Acute thyroiditis
0.000 0.356 0.644
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.356 0.644
E27.9 Disorder of adrenal gland, unspecified
0.000 0.356 0.644
L81.8 Other specified disorders of pigmentation
0.000 0.357 0.642
L84 Corns and callosities
0.000 0.358 0.642
L57.4 Cutis laxa senilis
0.000 0.358 0.641
L95.9 Vasculitis limited to skin, unspecified
0.000 0.360 0.640
H18 Other disorders of cornea
0.000 0.362 0.638
M22 Disorders of patella
0.000 0.363 0.637
H20.9 Iridocyclitis, unspecified
0.000 0.364 0.636
E27.5 Adrenomedullary hyperfunction
0.000 0.365 0.635
E27.0 Other adrenocortical overactivity
0.000 0.365 0.635
J37 Chronic laryngitis and laryngotracheitis
0.000 0.366 0.634
H57.1 Ocular pain
0.000 0.367 0.633
J96 Respiratory failure, not elsewhere classified
0.000 0.368 0.632
D69.8 Other specified haemorrhagic conditions
0.000 0.369 0.631
D69.4 Other primary thrombocytopenia
0.000 0.369 0.631
D69.1 Qualitative platelet defects
0.000 0.369 0.631
H31 Other disorders of choroid
0.000 0.369 0.631
E07.1 Dyshormogenetic goitre
0.000 0.369 0.630
E07.0 Hypersecretion of calcitonin
0.000 0.369 0.630
E20.9 Hypoparathyroidism, unspecified
0.000 0.371 0.629
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.374 0.626
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.374 0.626
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.374 0.626
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.374 0.626
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.374 0.626
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.374 0.626
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.374 0.626
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.374 0.626
D86.9 Sarcoidosis, unspecified
0.000 0.375 0.625
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.375 0.624
N42.8 Other specified disorders of prostate
0.624 0.376 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.377 0.623
E22 Hyperfunction of pituitary gland
0.000 0.377 0.623
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.378 0.622
L98.5 Mucinosis of skin
0.000 0.378 0.622
G90-G99 Other disorders of the nervous system
0.000 0.383 0.617
E28.3 Primary ovarian failure
0.000 0.383 0.617
H53-H54 Visual disturbances and blindness
0.000 0.384 0.616
H02.6 Xanthelasma of eyelid
0.000 0.386 0.614
D52.8 Other folate deficiency anaemias
0.000 0.387 0.613
D52.1 Drug-induced folate deficiency anaemia
0.000 0.387 0.613
D52.0 Dietary folate deficiency anaemia
0.000 0.387 0.613
L29.8 Other pruritus
0.000 0.388 0.612
L23 Allergic contact dermatitis
0.000 0.388 0.611
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.389 0.611
D61 Other aplastic anaemias
0.000 0.389 0.611
E28.2 Polycystic ovarian syndrome
0.000 0.390 0.610
J20.9 Acute bronchitis, unspecified
0.000 0.392 0.608
L29.1 Pruritus scroti
0.000 0.392 0.608
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.395 0.605
M06.38 Rheumatoid nodule (Other)
0.000 0.395 0.605
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.395 0.605
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.395 0.605
M06.33 Rheumatoid nodule (Forearm)
0.000 0.395 0.605
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.395 0.605
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.395 0.605
H01.8 Other specified inflammation of eyelid
0.000 0.396 0.604
N43 Hydrocele and spermatocele
0.603 0.397 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.399 0.601
D55-D59 Haemolytic anaemias
0.000 0.399 0.601
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.400 0.600
H05.3 Deformity of orbit
0.000 0.400 0.600
L94.8 Other specified localised connective tissue disorders
0.000 0.400 0.599
L94.6 Ainhum
0.000 0.400 0.599
L94.5 Poikiloderma vasculare atrophicans
0.000 0.400 0.599
L94.4 Gottron's papules
0.000 0.400 0.599
L94.3 Sclerodactyly
0.000 0.400 0.599
L94.1 Linear scleroderma
0.000 0.400 0.599
H02.2 Lagophthalmos
0.000 0.403 0.597
M33 Dermatopolymyositis
0.000 0.405 0.595
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.405 0.595
L21.8 Other seborrhoeic dermatitis
0.000 0.406 0.594
L21.1 Seborrhoeic infantile dermatitis
0.000 0.406 0.594
L21.0 Seborrhoea capitis
0.000 0.406 0.594
H16.8 Other keratitis
0.000 0.406 0.594
H16.4 Corneal neovascularisation
0.000 0.406 0.594
H16.3 Interstitial and deep keratitis
0.000 0.406 0.594
H16.2 Keratoconjunctivitis
0.000 0.406 0.594
H16.1 Other superficial keratitis without conjunctivitis
0.000 0.406 0.594
E27.2 Addisonian crisis
0.000 0.409 0.591
M11 Other crystal arthropathies
0.000 0.409 0.590
H15 Disorders of sclera
0.000 0.410 0.589
J40 Bronchitis, not specified as acute or chronic
0.000 0.410 0.590
M14 Arthropathies in other diseases classified elsewhere
0.000 0.411 0.589
E04.8 Other specified non-toxic goitre
0.000 0.411 0.589
H40-H42 Glaucoma
0.000 0.414 0.586
E23.6 Other disorders of pituitary gland
0.000 0.414 0.586
L85.8 Other specified epidermal thickening
0.000 0.415 0.585
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.415 0.585
L93.2 Other local lupus erythematosus
0.000 0.415 0.585
L93.1 Subacute cutaneous lupus erythematosus
0.000 0.415 0.585
J42 Unspecified chronic bronchitis
0.000 0.416 0.584
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.584 0.416 0.000
J21.9 Acute bronchiolitis, unspecified
0.000 0.416 0.584
H05.8 Other disorders of orbit
0.000 0.418 0.582
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.418 0.582
M32.8 Other forms of systemic lupus erythematosus
0.000 0.418 0.582
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.418 0.582
E40-E46 Malnutrition
0.000 0.419 0.581
E23.2 Diabetes insipidus
0.000 0.419 0.581
N42.1 Congestion and haemorrhage of prostate
0.581 0.419 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.420 0.580
E65-E68 Obesity and other hyperalimentation
0.000 0.420 0.580
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.000 0.423 0.577
L94.9 Localised connective tissue disorder, unspecified
0.000 0.423 0.577
L28.1 Prurigo nodularis
0.000 0.426 0.574
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.000 0.427 0.572
D62 Acute posthaemorrhagic anaemia
0.000 0.428 0.572
E04.9 Non-toxic goitre, unspecified
0.000 0.429 0.571
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.430 0.570
L27.8 Dermatitis due to other substances taken internally
0.000 0.430 0.570
L27.2 Dermatitis due to ingested food
0.000 0.430 0.570
J00-J06 Acute upper respiratory infections
0.000 0.430 0.570
J95.5 Postprocedural subglottic stenosis
0.000 0.430 0.570
J95.4 Mendelson's syndrome
0.000 0.430 0.570
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.430 0.570
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.430 0.570
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.430 0.570

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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