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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28680850
log Bayes Factor = <0.0001
Chromosome 8   position 1,373,720  (GRCh37) Explore rs28680850 on Ensembl!
Variant rs28680850 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E07 Other disorders of thyroid
0.000 0.980 0.020
E07.9 Disorder of thyroid, unspecified
0.000 0.980 0.020
E05.9 Thyrotoxicosis, unspecified
0.000 0.980 0.020
E00-E07 Disorders of thyroid gland
0.000 0.982 0.018
E06 Thyroiditis
0.000 0.982 0.018
E07.8 Other specified disorders of thyroid
0.000 0.982 0.018
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.982 0.018
E06.3 Autoimmune thyroiditis
0.000 0.983 0.017
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.983 0.017
E10.3 With ophthalmic complications
0.000 0.983 0.017
F33 Recurrent depressive disorder
0.000 0.984 0.016
E06.9 Thyroiditis, unspecified
0.000 0.984 0.016
E10 Insulin-dependent diabetes mellitus
0.000 0.985 0.015
E10.4 With neurological complications
0.000 0.985 0.015
E07.1 Dyshormogenetic goitre
0.000 0.986 0.014
E07.0 Hypersecretion of calcitonin
0.000 0.986 0.014
F33.9 Recurrent depressive disorder, unspecified
0.000 0.986 0.014
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.986 0.014
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.986 0.014
E10.5 With peripheral circulatory complications
0.000 0.986 0.014
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.986 0.014
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.987 0.013
E00 Congenital iodine-deficiency syndrome
0.000 0.987 0.013
E06.5 Other chronic thyroiditis
0.000 0.987 0.013
E06.4 Drug-induced thyroiditis
0.000 0.987 0.013
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.987 0.013
E06.1 Subacute thyroiditis
0.000 0.987 0.013
E06.0 Acute thyroiditis
0.000 0.987 0.013
E10.8 With unspecified complications
0.000 0.987 0.013
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.987 0.013
E05.5 Thyroid crisis or storm
0.000 0.987 0.013
E05.4 Thyrotoxicosis factitia
0.000 0.987 0.013
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.987 0.013
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.987 0.013
E10-E14 Diabetes mellitus
0.000 0.987 0.013
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.988 0.012
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.988 0.012
F33.8 Other recurrent depressive disorders
0.000 0.988 0.011
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.988 0.011
E10.7 With multiple complications
0.000 0.989 0.011
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.989 0.011
E10.0 With coma
0.000 0.989 0.011
E10.6 With other specified complications
0.000 0.989 0.011
E20-E35 Disorders of other endocrine glands
0.000 0.989 0.011
E40-E46 Malnutrition
0.000 0.989 0.011
E14 Unspecified diabetes mellitus
0.000 0.989 0.011
E05.8 Other thyrotoxicosis
0.000 0.989 0.010
E22 Hyperfunction of pituitary gland
0.000 0.990 0.010
E10.2 With renal complications
0.000 0.990 0.010
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.990 0.010
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.990 0.010
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.990 0.010
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.990 0.010
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.990 0.010
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.990 0.010
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.990 0.010
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.990 0.010
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.990 0.010
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.990 0.010
E13 Other specified diabetes mellitus
0.000 0.990 0.010
E14.9 Without complications
0.000 0.990 0.010
E46 Unspecified protein-energy malnutrition
0.000 0.990 0.010
E23 Hypofunction and other disorders of pituitary gland
0.000 0.990 0.010
E12 Malnutrition-related diabetes mellitus
0.000 0.990 0.009
E21.3 Hyperparathyroidism, unspecified
0.000 0.991 0.009
E24 Cushing's syndrome
0.000 0.991 0.009
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.991 0.008
E14.4 With neurological complications
0.000 0.992 0.008
E22.1 Hyperprolactinaemia
0.000 0.992 0.008
E24.9 Cushing's syndrome, unspecified
0.000 0.992 0.008
M24.1 Other articular cartilage disorders
0.000 0.992 0.008
E23.2 Diabetes insipidus
0.000 0.992 0.008
E65-E68 Obesity and other hyperalimentation
0.000 0.992 0.008
E10.1 With ketoacidosis
0.000 0.992 0.008
E23.0 Hypopituitarism
0.000 0.992 0.008
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.992 0.008
E32 Diseases of thymus
0.000 0.992 0.008
E31 Polyglandular dysfunction
0.000 0.992 0.008
E30 Disorders of puberty, not elsewhere classified
0.000 0.992 0.008
E25 Adrenogenital disorders
0.000 0.992 0.008
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.992 0.008
M24.13 Other articular cartilage disorders (Forearm)
0.000 0.992 0.008
N39.8 Other specified disorders of urinary system
0.000 0.992 0.008
E14.8 With unspecified complications
0.000 0.992 0.008
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.992 0.008
E45 Retarded development following protein-energy malnutrition
0.000 0.992 0.008
E43 Unspecified severe protein-energy malnutrition
0.000 0.992 0.008
E42 Marasmic kwashiorkor
0.000 0.992 0.008
E41 Nutritional marasmus
0.000 0.992 0.008
E40 Kwashiorkor
0.000 0.992 0.008
E14.7 With multiple complications
0.000 0.992 0.008
E14.2 Withrenal complications
0.000 0.992 0.008
E14.0 With coma
0.000 0.992 0.008
E14.1 With ketoacidosis
0.000 0.992 0.008
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.992 0.008
E22.8 Other hyperfunction of pituitary gland
0.000 0.992 0.008
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.992 0.008
E14.5 With peripheral circulatory complications
0.000 0.992 0.008
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.000 0.992 0.008
E03 Other hypothyroidism
0.000 0.992 0.008
E22.0 Acromegaly and pituitary gigantism
0.000 0.992 0.008
D48.1 Connective and other soft tissue
0.008 0.992 0.000
E27 Other disorders of adrenal gland
0.000 0.992 0.008
E26 Hyperaldosteronism
0.000 0.992 0.007
E23.6 Other disorders of pituitary gland
0.000 0.992 0.007
E13.9 Without complications
0.000 0.992 0.007
E21.4 Other specified disorders of parathyroid gland
0.000 0.993 0.007
E21.2 Other hyperparathyroidism
0.000 0.993 0.007
E13.8 With unspecified complications
0.000 0.993 0.007
E13.7 With multiple complications
0.000 0.993 0.007
E13.6 With other specified complications
0.000 0.993 0.007
E13.5 With peripheral circulatory complications
0.000 0.993 0.007
E13.4 With neurological complications
0.000 0.993 0.007
E13.3 With ophthalmic complications
0.000 0.993 0.007
E13.2 With renal complications
0.000 0.993 0.007
E13.1 With ketoacidosis
0.000 0.993 0.007
E13.0 With coma
0.000 0.993 0.007
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.993 0.007
E23.1 Drug-induced hypopituitarism
0.000 0.993 0.007
E20 Hypoparathyroidism
0.000 0.993 0.007
E12.9 Without complications
0.000 0.993 0.007
E12.8 With unspecified complications
0.000 0.993 0.007
E12.7 With multiple complications
0.000 0.993 0.007
E12.6 With other specified complications
0.000 0.993 0.007
E12.5 With peripheral circulatory complications
0.000 0.993 0.007
E12.4 With neurological complications
0.000 0.993 0.007
E12.3 With ophthalmic complications
0.000 0.993 0.007
E12.2 With renal complications
0.000 0.993 0.007
E12.1 With ketoacidosis
0.000 0.993 0.007
E12.0 With coma
0.000 0.993 0.007
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.993 0.007
E14.3 With ophthalmic complications
0.000 0.993 0.007
E24.8 Other Cushing's syndrome
0.000 0.993 0.007
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.993 0.007
E24.3 Ectopic ACTH syndrome
0.000 0.993 0.007
E24.1 Nelson's syndrome
0.000 0.993 0.007
E24.0 Pituitary-dependent Cushing's disease
0.000 0.993 0.007
E23.7 Disorder of pituitary gland, unspecified
0.000 0.993 0.007
E24.2 Drug-induced Cushing's syndrome
0.000 0.993 0.006
E29 Testicular dysfunction
0.000 0.994 0.006
E21.0 Primary hyperparathyroidism
0.000 0.994 0.006
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.006 0.994 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.994 0.006
F32.1 Moderate depressive episode
0.000 0.994 0.006
K61.0 Anal abscess
0.006 0.994 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.000 0.994 0.006
M24.18 Other articular cartilage disorders (Other)
0.000 0.994 0.006
M24.14 Other articular cartilage disorders (Hand)
0.000 0.994 0.006
M24.12 Other articular cartilage disorders (Upper arm)
0.000 0.994 0.006
M24.10 Other articular cartilage disorders (Multiple sites)
0.000 0.994 0.006
E67 Other hyperalimentation
0.000 0.994 0.006
E68 Sequelae of hyperalimentation
0.000 0.994 0.006
E27.2 Addisonian crisis
0.000 0.994 0.006
E25.9 Adrenogenital disorder, unspecified
0.000 0.994 0.006
E25.8 Other adrenogenital disorders
0.000 0.994 0.006
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.994 0.006
E30.9 Disorder of puberty, unspecified
0.000 0.994 0.006
E30.8 Other disorders of puberty
0.000 0.994 0.006
E30.1 Precocious puberty
0.000 0.994 0.006
E30.0 Delayed puberty
0.000 0.994 0.006
E31.9 Polyglandular dysfunction, unspecified
0.000 0.994 0.006
E31.8 Other polyglandular dysfunction
0.000 0.994 0.006
E31.1 Polyglandular hyperfunction
0.000 0.994 0.006
E31.0 Autoimmune polyglandular failure
0.000 0.994 0.006
E32.9 Disease of thymus, unspecified
0.000 0.994 0.006
E32.8 Other diseases of thymus
0.000 0.994 0.006
E32.1 Abscess of thymus
0.000 0.994 0.006
E32.0 Persistent hyperplasia of thymus
0.000 0.994 0.006
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.994 0.006
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.994 0.006
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.994 0.006
E66 Obesity
0.000 0.994 0.006
E27.8 Other specified disorders of adrenal gland
0.000 0.994 0.006
E14.6 With other specified complications
0.000 0.994 0.006
E15 Nondiabetic hypoglycaemic coma
0.000 0.994 0.006
E27.9 Disorder of adrenal gland, unspecified
0.000 0.994 0.006
E44.1 Mild protein-energy malnutrition
0.000 0.994 0.006
E44.0 Moderate protein-energy malnutrition
0.000 0.994 0.006
E34 Other endocrine disorders
0.000 0.994 0.006
E11.3 With ophthalmic complications
0.000 0.994 0.006
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.006 0.994 0.000
E04 Other non-toxic goitre
0.000 0.994 0.006
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.006 0.994 0.000
E03.5 Myxoedema coma
0.000 0.994 0.006
E03.4 Atrophy of thyroid (acquired)
0.000 0.994 0.006
E03.3 Postinfectious hypothyroidism
0.000 0.994 0.006
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.994 0.006
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.994 0.006
E26.9 Hyperaldosteronism, unspecified
0.000 0.994 0.005
E26.8 Other hyperaldosteronism
0.000 0.994 0.005
E26.1 Secondary hyperaldosteronism
0.000 0.994 0.005
E27.5 Adrenomedullary hyperfunction
0.000 0.994 0.006
E27.0 Other adrenocortical overactivity
0.000 0.994 0.006
M80.9 Unspecified osteoporosis with pathological fracture
0.006 0.994 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.994 0.006
E66.0 Obesity due to excess calories
0.000 0.994 0.006
E20.8 Other hypoparathyroidism
0.000 0.995 0.005
E20.1 Pseudohypoparathyroidism
0.000 0.995 0.005
E20.0 Idiopathic hypoparathyroidism
0.000 0.995 0.005
E03.1 Congenital hypothyroidism without goitre
0.000 0.995 0.005
E65 Localised adiposity
0.000 0.995 0.005
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.005 0.995 0.000
E28 Ovarian dysfunction
0.000 0.995 0.005
M84.1 Nonunion of fracture [pseudarthrosis]
0.005 0.995 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.995 0.005
E26.0 Primary hyperaldosteronism
0.000 0.995 0.005
M82.1 Osteoporosis in endocrine disorders
0.005 0.995 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.000 0.995 0.005
E66.8 Other obesity
0.000 0.995 0.005
E11.0 With coma
0.000 0.995 0.005
E16 Other disorders of pancreatic internal secretion
0.000 0.995 0.005
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.005 0.995 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.995 0.005
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.005 0.995 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.995 0.005
E29.8 Other testicular dysfunction
0.000 0.995 0.005
E29.0 Testicular hyperfunction
0.000 0.995 0.005
M84 Disorders of continuity of bone
0.005 0.995 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.005 0.995 0.000
E34.0 Carcinoid syndrome
0.000 0.995 0.005
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.005 0.995 0.000
M82 Osteoporosis in diseases classified elsewhere
0.005 0.995 0.000
D48.7 Other specified sites
0.005 0.995 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.995 0.005
S02.50 Fracture of tooth (closed)
0.005 0.995 0.000
E03.8 Other specified hypothyroidism
0.000 0.995 0.005
E67.8 Other specified hyperalimentation
0.000 0.995 0.004
E67.3 Hypervitaminosis D
0.000 0.995 0.004
E67.2 Megavitamin-B6 syndrome
0.000 0.995 0.004
E67.1 Hypercarotenaemia
0.000 0.995 0.004
E67.0 Hypervitaminosis A
0.000 0.995 0.004
E66.1 Drug-induced obesity
0.000 0.995 0.004
M80 Osteoporosis with pathological fracture
0.005 0.995 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.005 0.995 0.000
C16.0 Cardia
0.005 0.995 0.000
E34.5 Androgen resistance syndrome
0.000 0.995 0.004
E34.4 Constitutional tall stature
0.000 0.995 0.004
E34.3 Short stature, not elsewhere classified
0.000 0.995 0.004
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.995 0.004
E34.1 Other hypersecretion of intestinal hormones
0.000 0.995 0.004
E04.8 Other specified non-toxic goitre
0.000 0.995 0.004
M80-M85 Disorders of bone density and structure
0.005 0.995 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.995 0.004
F32 Depressive episode
0.000 0.996 0.004
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.004 0.996 0.000
D48.5 Skin
0.004 0.996 0.000
E50-E64 Other nutritional deficiencies
0.000 0.996 0.004
M24.17 Other articular cartilage disorders (Ankle and foot)
0.000 0.996 0.004
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.004 0.996 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.004 0.996 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.004 0.996 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.004 0.996 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.004 0.996 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.004 0.996 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.004 0.996 0.000
Z50.8 Care involving use of rehabilitation procedures
0.000 0.996 0.004
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.996 0.004
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.004 0.996 0.000
F30-F39 Mood [affective] disorders
0.000 0.996 0.004
D48.4 Peritoneum
0.004 0.996 0.000
D48.3 Retroperitoneum
0.004 0.996 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.004 0.996 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.996 0.004
E28.8 Other ovarian dysfunction
0.000 0.996 0.004
E28.1 Androgen excess
0.000 0.996 0.004
E28.0 Oestrogen excess
0.000 0.996 0.004
M84.8 Other disorders of continuity of bone
0.004 0.996 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.004 0.996 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.004 0.996 0.000
F32.0 Mild depressive episode
0.000 0.996 0.004
E11.7 With multiple complications
0.000 0.996 0.004
K61.4 Intrasphincteric abscess
0.004 0.996 0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)
0.004 0.996 0.000
M82.18 Osteoporosis in endocrine disorders (Other)
0.004 0.996 0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)
0.004 0.996 0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)
0.004 0.996 0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)
0.004 0.996 0.000
M82.14 Osteoporosis in endocrine disorders (Hand)
0.004 0.996 0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)
0.004 0.996 0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)
0.004 0.996 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.004 0.996 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.000 0.996 0.004
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.004 0.996 0.000
E16.1 Other hypoglycaemia
0.000 0.996 0.004
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.996 0.004
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.996 0.004
E16.4 Abnormal secretion of gastrin
0.000 0.996 0.004
E16.3 Increased secretion of glucagon
0.000 0.996 0.004
D48.0 Bone and articular cartilage
0.004 0.996 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.004 0.996 0.000
M84.2 Delayed union of fracture
0.004 0.996 0.000
K66.8 Other specified disorders of peritoneum
0.000 0.996 0.004
D48.6 Breast
0.004 0.996 0.000
M83 Adult osteomalacia
0.004 0.996 0.000
E11.8 With unspecified complications
0.000 0.996 0.004
M84.9 Disorder of continuity of bone, unspecified
0.004 0.996 0.000
M84.3 Stress fracture, not elsewhere classified
0.004 0.996 0.000
M84.0 Malunion of fracture
0.004 0.996 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.004 0.996 0.000
M40.26 Other and unspecified kyphosis (Lumbar region)
0.004 0.996 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.000 0.996 0.004
E16.2 Hypoglycaemia, unspecified
0.000 0.996 0.004
M82.8 Osteoporosis in other diseases classified elsewhere
0.004 0.996 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.004 0.996 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.004 0.996 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.004 0.996 0.000
E34.8 Other specified endocrine disorders
0.000 0.996 0.003
M84.4 Pathological fracture, not elsewhere classified
0.004 0.996 0.000
M40.29 Other and unspecified kyphosis (Site unspecified)
0.004 0.996 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.003 0.996 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.003 0.996 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.003 0.996 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.003 0.996 0.000
N87.1 Moderate cervical dysplasia
0.004 0.996 0.000
M80.8 Other osteoporosis with pathological fracture
0.003 0.996 0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)
0.003 0.996 0.000
R22.0 Localised swelling, mass and lump, head
0.000 0.997 0.003
E11.2 With renal complications
0.000 0.997 0.003
I60.9 Subarachnoid haemorrhage, unspecified
0.003 0.997 0.000
M40.2 Other and unspecified kyphosis
0.003 0.997 0.000
K61 Abscess of anal and rectal regions
0.003 0.997 0.000
G31.8 Other specified degenerative diseases of nervous system
0.003 0.997 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.003 0.997 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.997 0.003
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.997 0.003
E63 Other nutritional deficiencies
0.000 0.997 0.003
E56 Other vitamin deficiencies
0.000 0.997 0.003
E50 Vitamin A deficiency
0.000 0.997 0.003
E60 Dietary zinc deficiency
0.000 0.997 0.003
E59 Dietary selenium deficiency
0.000 0.997 0.003
E54 Ascorbic acid deficiency
0.000 0.997 0.003
E52 Niacin deficiency [pellagra]
0.000 0.997 0.003
E28.3 Primary ovarian failure
0.000 0.997 0.003
C83.5 Lymphoblastic (diffuse)
0.003 0.997 0.000
C83.1 Small cleaved cell (diffuse)
0.003 0.997 0.000
C83.3 Large cell (diffuse)
0.003 0.997 0.000
M83.1 Senile osteomalacia
0.003 0.997 0.000
M84.02 Malunion of fracture (Upper arm)
0.003 0.997 0.000
M84.01 Malunion of fracture (Shoulder region)
0.003 0.997 0.000
F38 Other mood [affective] disorders
0.000 0.997 0.003
E34.9 Endocrine disorder, unspecified
0.000 0.997 0.003
K29.0 Acute haemorrhagic gastritis
0.003 0.997 0.000
F32.8 Other depressive episodes
0.000 0.997 0.003
M84.89 Other disorders of continuity of bone (Site unspecified)
0.003 0.997 0.000
M84.88 Other disorders of continuity of bone (Other)
0.003 0.997 0.000
M84.86 Other disorders of continuity of bone (Lower leg)
0.003 0.997 0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)
0.003 0.997 0.000
M84.84 Other disorders of continuity of bone (Hand)
0.003 0.997 0.000
M84.83 Other disorders of continuity of bone (Forearm)
0.003 0.997 0.000
M84.82 Other disorders of continuity of bone (Upper arm)
0.003 0.997 0.000
M84.81 Other disorders of continuity of bone (Shoulder region)
0.003 0.997 0.000
M84.80 Other disorders of continuity of bone (Multiple sites)
0.003 0.997 0.000
E51 Thiamine deficiency
0.000 0.997 0.003
E29.1 Testicular hypofunction
0.000 0.997 0.003
K66.1 Haemoperitoneum
0.000 0.997 0.003
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.997 0.003
E11.6 With other specified complications
0.000 0.997 0.003
M81 Osteoporosis without pathological fracture
0.003 0.997 0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)
0.003 0.997 0.000
M85 Other disorders of bone density and structure
0.003 0.997 0.000
M84.04 Malunion of fracture (Hand)
0.003 0.997 0.000
E53 Deficiency of other B group vitamins
0.000 0.997 0.003
M84.26 Delayed union of fracture (Lower leg)
0.003 0.997 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.003 0.997 0.000
F32.9 Depressive episode, unspecified
0.000 0.997 0.003
F34 Persistent mood [affective] disorders
0.000 0.997 0.003
E11.1 With ketoacidosis
0.000 0.997 0.003
M84.29 Delayed union of fracture (Site unspecified)
0.003 0.997 0.000
M84.28 Delayed union of fracture (Other)
0.003 0.997 0.000
M84.27 Delayed union of fracture (Ankle and foot)
0.003 0.997 0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)
0.003 0.997 0.000
M84.24 Delayed union of fracture (Hand)
0.003 0.997 0.000
M84.23 Delayed union of fracture (Forearm)
0.003 0.997 0.000
M84.22 Delayed union of fracture (Upper arm)
0.003 0.997 0.000
M84.21 Delayed union of fracture (Shoulder region)
0.003 0.997 0.000
M84.20 Delayed union of fracture (Multiple sites)
0.003 0.997 0.000
C83.6 Undifferentiated (diffuse)
0.003 0.997 0.000
C83.4 Immunoblastic (diffuse)
0.003 0.997 0.000
C83.2 Mixed small and large cell (diffuse)
0.003 0.997 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.997 0.003
C83.7 Burkitt's tumour
0.003 0.997 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.003 0.997 0.000
M83.9 Adult osteomalacia, unspecified
0.003 0.997 0.000
M83.8 Other adult osteomalacia
0.003 0.997 0.000
M83.5 Other drug-induced osteomalacia in adults
0.003 0.997 0.000
M83.4 Aluminum bone disease
0.003 0.997 0.000
M83.3 Adult osteomalacia due to malnutrition
0.003 0.997 0.000
M83.2 Adult osteomalacia due to malabsorption
0.003 0.997 0.000
M83.0 Puerperal osteomalacia
0.003 0.997 0.000
M83.12 Senile osteomalacia (Upper arm)
0.003 0.997 0.000
M84.09 Malunion of fracture (Site unspecified)
0.003 0.997 0.000
M84.08 Malunion of fracture (Other)
0.003 0.997 0.000
M84.00 Malunion of fracture (Multiple sites)
0.003 0.997 0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)
0.003 0.997 0.000
M84.38 Stress fracture, not elsewhere classified (Other)
0.003 0.997 0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)
0.003 0.997 0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)
0.003 0.997 0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)
0.003 0.997 0.000
M84.34 Stress fracture, not elsewhere classified (Hand)
0.003 0.997 0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)
0.003 0.997 0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)
0.003 0.997 0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)
0.003 0.997 0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)
0.003 0.997 0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)
0.003 0.997 0.000
M84.98 Disorder of continuity of bone, unspecified (Other)
0.003 0.997 0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)
0.003 0.997 0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)
0.003 0.997 0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)
0.003 0.997 0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)
0.003 0.997 0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)
0.003 0.997 0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)
0.003 0.997 0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)
0.003 0.997 0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)
0.003 0.997 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.003 0.997 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.003 0.997 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.003 0.997 0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)
0.003 0.997 0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)
0.003 0.997 0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)
0.003 0.997 0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)
0.003 0.997 0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)
0.003 0.997 0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)
0.003 0.997 0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)
0.003 0.997 0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)
0.003 0.997 0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)
0.003 0.997 0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)
0.003 0.997 0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)
0.003 0.997 0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)
0.003 0.997 0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)
0.003 0.997 0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)
0.003 0.997 0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)
0.003 0.997 0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)
0.003 0.997 0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)
0.003 0.997 0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)
0.003 0.997 0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)
0.003 0.997 0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)
0.003 0.997 0.000
M84.06 Malunion of fracture (Lower leg)
0.003 0.997 0.000
E61 Deficiency of other nutrient elements
0.000 0.997 0.003
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)
0.003 0.997 0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)
0.003 0.997 0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)
0.003 0.997 0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)
0.003 0.997 0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)
0.003 0.997 0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)
0.003 0.997 0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)
0.003 0.997 0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)
0.003 0.997 0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)
0.003 0.997 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.003 0.997 0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)
0.003 0.997 0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)
0.003 0.997 0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)
0.003 0.997 0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)
0.003 0.997 0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)
0.003 0.997 0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)
0.003 0.997 0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)
0.003 0.997 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.997 0.003
M80.5 Idiopathic osteoporosis with pathological fracture
0.003 0.997 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.003 0.997 0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)
0.003 0.997 0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)
0.003 0.997 0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)
0.003 0.997 0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)
0.003 0.997 0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)
0.003 0.997 0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)
0.003 0.997 0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)
0.003 0.997 0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)
0.003 0.997 0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)
0.003 0.997 0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)
0.003 0.997 0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)
0.003 0.997 0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)
0.003 0.997 0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)
0.003 0.997 0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)
0.003 0.997 0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)
0.003 0.997 0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)
0.003 0.997 0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)
0.003 0.997 0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)
0.003 0.997 0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)
0.003 0.997 0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)
0.003 0.997 0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)
0.003 0.997 0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)
0.003 0.997 0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)
0.003 0.997 0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)
0.003 0.997 0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)
0.003 0.997 0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)
0.003 0.997 0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)
0.003 0.997 0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)
0.003 0.997 0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)
0.003 0.997 0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)
0.003 0.997 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.003 0.997 0.000
E58 Dietary calcium deficiency
0.000 0.997 0.003
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.997 0.003
M80.89 Other osteoporosis with pathological fracture (Site unspecified)
0.003 0.997 0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)
0.003 0.997 0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)
0.003 0.997 0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)
0.003 0.997 0.000
M80.84 Other osteoporosis with pathological fracture (Hand)
0.003 0.997 0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)
0.003 0.997 0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)
0.003 0.997 0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)
0.003 0.997 0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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