TreeWAS – Variant ID: rs2885135

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
A41.9 Septicaemia, unspecified	0.448	0.552	0.000
A41 Other septicaemia	0.447	0.553	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.418	0.582	0.000
A30-A49 Other bacterial diseases	0.417	0.583	0.000
A49 Bacterial infection of unspecified site	0.412	0.588	0.000
A49.0 Staphylococcal infection, unspecified	0.401	0.599	0.000
A41.8 Other specified septicaemia	0.400	0.600	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.355	0.644	0.000
A48 Other bacterial diseases, not elsewhere classified	0.344	0.656	0.000
A49.8 Other bacterial infections of unspecified site	0.332	0.668	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.331	0.669	0.000
A49.9 Bacterial infection, unspecified	0.324	0.676	0.000
A41.4 Septicaemia due to anaerobes	0.321	0.679	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.321	0.679	0.000
A40 Streptococcal septicaemia	0.312	0.688	0.000
A39 Meningococcal infection	0.299	0.701	0.000
A44 Bartonellosis	0.299	0.701	0.000
A43 Nocardiosis	0.299	0.701	0.000
A42 Actinomycosis	0.299	0.701	0.000
A37 Whooping cough	0.299	0.701	0.000
A36 Diphtheria	0.299	0.701	0.000
A32 Listeriosis	0.299	0.701	0.000
A31 Infection due to other mycobacteria	0.299	0.701	0.000
A30 Leprosy [Hansen's disease]	0.299	0.701	0.000
A38 Scarlet fever	0.299	0.701	0.000
A35 Other tetanus	0.299	0.701	0.000
A34 Obstetrical tetanus	0.299	0.701	0.000
A33 Tetanus neonatorum	0.299	0.701	0.000
A49.3 Mycoplasma infection, unspecified	0.295	0.705	0.000
A48.1 Legionnaires' disease	0.292	0.708	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.291	0.709	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.286	0.714	0.000
A40.0 Septicaemia due to streptococcus, group A	0.278	0.722	0.000
A49.1 Streptococcal infection, unspecified	0.274	0.726	0.000
A48.8 Other specified bacterial diseases	0.248	0.752	0.000
A48.4 Brazilian purpuric fever	0.247	0.753	0.000
A48.3 Toxic shock syndrome	0.247	0.753	0.000
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.247	0.753	0.000
A48.0 Gas gangrene	0.247	0.753	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.227	0.773	0.000
A46 Erysipelas	0.224	0.776	0.000
A40.2 Septicaemia due to streptococcus, group D	0.224	0.776	0.000
A40.1 Septicaemia due to streptococcus, group B	0.224	0.776	0.000
A39.0 Meningococcal meningitis	0.218	0.782	0.000
A39.9 Meningococcal infection, unspecified	0.215	0.785	0.000
A39.8 Other meningococcal infections	0.215	0.785	0.000
A39.5 Meningococcal heart disease	0.215	0.785	0.000
A39.3 Chronic meningococcaemia	0.215	0.785	0.000
A39.2 Acute meningococcaemia	0.215	0.785	0.000
A39.1 Waterhouse-Friderichsen syndrome	0.215	0.785	0.000
A30.9 Leprosy, unspecified	0.214	0.785	0.000
A30.8 Other forms of leprosy	0.214	0.785	0.000
A30.5 Lepromatous leprosy	0.214	0.785	0.000
A30.4 Borderline lepromatous leprosy	0.214	0.785	0.000
A30.3 Borderline leprosy	0.214	0.785	0.000
A30.2 Borderline tuberculoid leprosy	0.214	0.785	0.000
A30.1 Tuberculoid leprosy	0.214	0.785	0.000
A30.0 Indeterminate leprosy	0.214	0.785	0.000
A31.9 Mycobacterial infection, unspecified	0.214	0.785	0.000
A31.8 Other mycobacterial infections	0.214	0.785	0.000
A31.1 Cutaneous mycobacterial infection	0.214	0.785	0.000
A31.0 Pulmonary mycobacterial infection	0.214	0.785	0.000
A32.9 Listeriosis, unspecified	0.214	0.785	0.000
A32.8 Other forms of listeriosis	0.214	0.785	0.000
A32.7 Listerial septicaemia	0.214	0.785	0.000
A32.1 Listerial meningitis and meningoencephalitis	0.214	0.785	0.000
A32.0 Cutaneous listeriosis	0.214	0.785	0.000
A36.9 Diphtheria, unspecified	0.214	0.785	0.000
A36.8 Other diphtheria	0.214	0.785	0.000
A36.3 Cutaneous diphtheria	0.214	0.785	0.000
A36.2 Laryngeal diphtheria	0.214	0.785	0.000
A36.1 Nasopharyngeal diphtheria	0.214	0.785	0.000
A36.0 Pharyngeal diphtheria	0.214	0.785	0.000
A37.9 Whooping cough, unspecified	0.214	0.785	0.000
A37.8 Whooping cough due to other Bordetella species	0.214	0.785	0.000
A37.1 Whooping cough due to Bordetella parapertussis	0.214	0.785	0.000
A37.0 Whooping cough due to Bordetella pertussis	0.214	0.785	0.000
A42.9 Actinomycosis, unspecified	0.214	0.785	0.000
A42.8 Other forms of actinomycosis	0.214	0.785	0.000
A42.7 Actinomycotic septicaemia	0.214	0.785	0.000
A42.2 Cervicofacial actinomycosis	0.214	0.785	0.000
A42.1 Abdominal actinomycosis	0.214	0.785	0.000
A42.0 Pulmonary actinomycosis	0.214	0.785	0.000
A43.9 Nocardiosis, unspecified	0.214	0.785	0.000
A43.8 Other forms of nocardiosis	0.214	0.785	0.000
A43.1 Cutaneous nocardiosis	0.214	0.785	0.000
A43.0 Pulmonary nocardiosis	0.214	0.785	0.000
A44.9 Bartonellosis, unspecified	0.214	0.785	0.000
A44.8 Other forms of bartonellosis	0.214	0.785	0.000
A44.1 Cutaneous and mucocutaneous bartonellosis	0.214	0.785	0.000
A44.0 Systemic bartonellosis	0.214	0.785	0.000
A39.4 Meningococcaemia, unspecified	0.212	0.788	0.000
A40.8 Other streptococcal septicaemia	0.211	0.789	0.000
A40.9 Streptococcal septicaemia, unspecified	0.136	0.863	0.001
S01.0 Open wound of scalp	0.043	0.957	0.000
S01 Open wound of head	0.040	0.960	0.000
S01.5 Open wound of lip and oral cavity	0.039	0.961	0.000
S01.4 Open wound of cheek and temporomandibular area	0.038	0.962	0.000
S01.9 Open wound of head, part unspecified	0.033	0.967	0.000
S01.7 Multiple open wounds of head	0.031	0.969	0.000
S01.8 Open wound of other parts of head	0.029	0.971	0.000
S01.1 Open wound of eyelid and periocular area	0.025	0.975	0.000
N02.9 Unspecified	0.021	0.979	0.000
S01.3 Open wound of ear	0.020	0.980	0.000
S00-S09 Injuries to the head	0.017	0.983	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.983	0.017
S05 Injury of eye and orbit	0.016	0.984	0.000
S01.2 Open wound of nose	0.015	0.984	0.000
N02 Recurrent and persistent haematuria	0.015	0.985	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.015	0.985	0.000
S92 Fracture of foot, except ankle	0.013	0.987	0.000
S00 Superficial injury of head	0.013	0.987	0.000
S92.1 Fracture of talus	0.013	0.987	0.000
S92.10 Fracture of talus (closed)	0.013	0.987	0.000
S05.8 Other injuries of eye and orbit	0.013	0.987	0.000
N02.2 Diffuse membranous glomerulonephritis	0.013	0.987	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.013	0.987	0.000
S00.5 Superficial injury of lip and oral cavity	0.013	0.987	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.012	0.987	0.000
S08 Traumatic amputation of part of head	0.012	0.987	0.000
S07 Crushing injury of head	0.012	0.987	0.000
S04 Injury of cranial nerves	0.012	0.987	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.012	0.987	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.012	0.988	0.000
O42.9 Premature rupture of membranes, unspecified	0.012	0.988	0.000
S90-S99 Injuries to the ankle and foot	0.012	0.988	0.000
S05.7 Avulsion of eye	0.012	0.988	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.012	0.988	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.012	0.988	0.000
S05.1 Contusion of eyeball and orbital tissues	0.012	0.988	0.000
S92.5 Fracture of other toe	0.012	0.988	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.012	0.988	0.000
S92.0 Fracture of calcaneus	0.012	0.988	0.000
N00-N08 Glomerular diseases	0.012	0.988	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.011	0.989	0.000
N02.6 Dense deposit disease	0.011	0.989	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.011	0.989	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.011	0.989	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.011	0.989	0.000
N02.1 Focal and segmental glomerular lesions	0.011	0.989	0.000
N02.0 Minor glomerular abnormality	0.011	0.989	0.000
S05.9 Injury of eye and orbit, part unspecified	0.011	0.989	0.000
S00.0 Superficial injury of scalp	0.011	0.989	0.000
S92.4 Fracture of great toe	0.011	0.989	0.000
S99 Other and unspecified injuries of ankle and foot	0.011	0.989	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.011	0.989	0.000
S92.7 Multiple fractures of foot	0.011	0.989	0.000
S00.9 Superficial injury of head, part unspecified	0.010	0.990	0.000
S91 Open wound of ankle and foot	0.010	0.990	0.000
S92.00 Fracture of calcaneus (closed)	0.010	0.990	0.000
S92.2 Fracture of other tarsal bone(s)	0.010	0.990	0.000
M06.9 Rheumatoid arthritis, unspecified	0.010	0.990	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.010	0.990	0.000
S92.51 Fracture of other toe (open)	0.010	0.990	0.000
S00.4 Superficial injury of ear	0.010	0.990	0.000
S92.9 Fracture of foot, unspecified	0.010	0.990	0.000
S99.9 Unspecified injury of ankle and foot	0.010	0.990	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.010	0.990	0.000
N05 Unspecified nephritic syndrome	0.010	0.990	0.000
N04 Nephrotic syndrome	0.010	0.990	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.010	0.990	0.000
S92.11 Fracture of talus (open)	0.009	0.990	0.000
S93.1 Dislocation of toe(s)	0.010	0.990	0.000
T43.2 Other and unspecified antidepressants	0.010	0.990	0.000
S91.3 Open wound of other parts of foot	0.009	0.991	0.000
S92.50 Fracture of other toe (closed)	0.009	0.991	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.009	0.991	0.000
O03.9 Complete or unspecified, without complication	0.009	0.991	0.000
N00 Acute nephritic syndrome	0.009	0.991	0.000
S06 Intracranial injury	0.009	0.991	0.000
S04.9 Injury of unspecified cranial nerve	0.009	0.991	0.000
S04.8 Injury of other cranial nerves	0.009	0.991	0.000
S04.7 Injury of accessory nerve	0.009	0.991	0.000
S04.6 Injury of acoustic nerve	0.009	0.991	0.000
S04.5 Injury of facial nerve	0.009	0.991	0.000
S04.4 Injury of abducent nerve	0.009	0.991	0.000
S04.3 Injury of trigeminal nerve	0.009	0.991	0.000
S04.2 Injury of trochlear nerve	0.009	0.991	0.000
S04.1 Injury of oculomotor nerve	0.009	0.991	0.000
S04.0 Injury of optic nerve and pathways	0.009	0.991	0.000
S07.9 Crushing injury of head, part unspecified	0.009	0.991	0.000
S07.8 Crushing injury of other parts of head	0.009	0.991	0.000
S07.1 Crushing injury of skull	0.009	0.991	0.000
S07.0 Crushing injury of face	0.009	0.991	0.000
S08.9 Traumatic amputation of unspecified part of head	0.009	0.991	0.000
S08.8 Traumatic amputation of other parts of head	0.009	0.991	0.000
S08.1 Traumatic amputation of ear	0.009	0.991	0.000
S08.0 Avulsion of scalp	0.009	0.991	0.000
T02 Fractures involving multiple body regions	0.009	0.991	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.009	0.991	0.000
T00-T07 Injuries involving multiple body regions	0.009	0.991	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.009	0.991	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.009	0.991	0.000
S03.4 Sprain and strain of jaw	0.009	0.991	0.000
S03.3 Dislocation of other and unspecified parts of head	0.009	0.991	0.000
S03.1 Dislocation of septal cartilage of nose	0.009	0.991	0.000
S03.0 Dislocation of jaw	0.009	0.991	0.000
S97 Crushing injury of ankle and foot	0.009	0.991	0.000
S00.7 Multiple superficial injuries of head	0.009	0.991	0.000
S98 Traumatic amputation of ankle and foot	0.009	0.991	0.000
S95 Injury of blood vessels at ankle and foot level	0.009	0.991	0.000
S94 Injury of nerves at ankle and foot level	0.009	0.991	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.009	0.991	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.009	0.991	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.009	0.991	0.000
S03.2 Dislocation of tooth	0.009	0.991	0.000
S09 Other and unspecified injuries of head	0.009	0.991	0.000
S00.1 Contusion of eyelid and periocular area	0.009	0.991	0.000
T58 Toxic effect of carbon monoxide	0.009	0.991	0.000
T88.5 Other complications of anaesthesia	0.009	0.991	0.000
N03 Chronic nephritic syndrome	0.009	0.991	0.000
S92.41 Fracture of great toe (open)	0.009	0.991	0.000
T43.6 Psychostimulants with abuse potential	0.009	0.991	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.009	0.991	0.000
S92.01 Fracture of calcaneus (open)	0.008	0.991	0.000
S92.40 Fracture of great toe (closed)	0.008	0.991	0.000
S92.70 Multiple fractures of foot (closed)	0.008	0.991	0.000
S91.0 Open wound of ankle	0.008	0.991	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.991	0.009
N07 Hereditary nephropathy, not elsewhere classified	0.008	0.991	0.000
N06 Isolated proteinuria with specified morphological lesion	0.008	0.991	0.000
N01 Rapidly progressive nephritic syndrome	0.008	0.991	0.000
S00.3 Superficial injury of nose	0.008	0.991	0.000
N05.8 Other	0.008	0.992	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.008	0.992	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.008	0.992	0.000
N02.8 Other	0.008	0.992	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.008	0.992	0.000
N04.2 Diffuse membranous glomerulonephritis	0.008	0.992	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
S99.8 Other specified injuries of ankle and foot	0.008	0.992	0.000
S93.0 Dislocation of ankle joint	0.008	0.992	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.008	0.992	0.000
S99.7 Multiple injuries of ankle and foot	0.008	0.992	0.000
T02.5 Fractures involving multiple regions of both lower limbs	0.008	0.992	0.000
S93.4 Sprain and strain of ankle	0.008	0.992	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.008	0.992	0.000
S93.5 Sprain and strain of toe(s)	0.008	0.992	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.008	0.992	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.008	0.992	0.000
S92.71 Multiple fractures of foot (open)	0.008	0.992	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.008	0.992	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.008	0.992	0.000
S06.4 Epidural haemorrhage	0.008	0.992	0.000
S92.3 Fracture of metatarsal bone	0.008	0.992	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.008	0.992	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
N00.9 Unspecified	0.008	0.992	0.000
N04.9 Unspecified	0.008	0.992	0.000
S91.7 Multiple open wounds of ankle and foot	0.008	0.992	0.000
S91.2 Open wound of toe(s) with damage to nail	0.008	0.992	0.000
S06.9 Intracranial injury, unspecified	0.007	0.992	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.007	0.992	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.007	0.992	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.008	0.992	0.000
T43.9 Psychotropic drug, unspecified	0.007	0.992	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.007	0.992	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.007	0.992	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.007	0.993	0.000
N05.2 Diffuse membranous glomerulonephritis	0.007	0.993	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.007	0.993	0.000
S92.91 Fracture of foot, unspecified (open)	0.007	0.993	0.000
S92.90 Fracture of foot, unspecified (closed)	0.007	0.993	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.007	0.993	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.993	0.007
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.007	0.993	0.000
N05.9 Unspecified	0.007	0.993	0.000
T79-T79 Certain early complications of trauma	0.007	0.993	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.007	0.993	0.000
N05.6 Dense deposit disease	0.007	0.993	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.007	0.993	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.007	0.993	0.000
N05.0 Minor glomerular abnormality	0.007	0.993	0.000
N04.8 Other	0.007	0.993	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.007	0.993	0.000
N04.6 Dense deposit disease	0.007	0.993	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.007	0.993	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.007	0.993	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.007	0.993	0.000
N04.1 Focal and segmental glomerular lesions	0.007	0.993	0.000
N04.0 Minor glomerular abnormality	0.007	0.993	0.000
T51 Toxic effect of alcohol	0.007	0.993	0.000
S06.5 Traumatic subdural haemorrhage	0.007	0.993	0.000
T00 Superficial injuries involving multiple body regions	0.007	0.993	0.000
S10-S19 Injuries to the neck	0.007	0.993	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.007	0.993	0.000
T54 Toxic effect of corrosive substances	0.007	0.993	0.000
T02.50 Fractures involving multiple regions of both lower limbs (closed)	0.007	0.993	0.000
S06.3 Focal brain injury	0.007	0.993	0.000
N03.1 Focal and segmental glomerular lesions	0.007	0.993	0.000
T01 Open wounds involving multiple body regions	0.007	0.993	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.007	0.993	0.000
S06.7 Intracranial injury with prolonged coma	0.007	0.993	0.000
S06.1 Traumatic cerebral oedema	0.007	0.993	0.000
N00.8 Other	0.007	0.993	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.007	0.993	0.000
N00.6 Dense deposit disease	0.007	0.993	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.007	0.993	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.007	0.993	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.007	0.993	0.000
N00.2 Diffuse membranous glomerulonephritis	0.007	0.993	0.000
N00.1 Focal and segmental glomerular lesions	0.007	0.993	0.000
N00.0 Minor glomerular abnormality	0.007	0.993	0.000
T56 Toxic effect of metals	0.007	0.993	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.007	0.993	0.000
T02.9 Multiple fractures, unspecified	0.007	0.993	0.000
T02.8 Fractures involving other combinations of body regions	0.007	0.993	0.000
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.007	0.993	0.000
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.007	0.993	0.000
T02.3 Fractures involving multiple regions of one lower limb	0.007	0.993	0.000
T02.2 Fractures involving multiple regions of one upper limb	0.007	0.993	0.000
T02.1 Fractures involving thorax with lower back and pelvis	0.007	0.993	0.000
T02.0 Fractures involving head with neck	0.007	0.993	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.007	0.993	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.007	0.993	0.000
T05 Traumatic amputations involving multiple body regions	0.007	0.993	0.000
T04 Crushing injuries involving multiple body regions	0.007	0.993	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.007	0.993	0.000
T07 Unspecified multiple injuries	0.007	0.993	0.000
T17 Foreign body in respiratory tract	0.007	0.993	0.000
T33-T35 Frostbite	0.007	0.993	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.007	0.993	0.000
T19 Foreign body in genito-urinary tract	0.007	0.993	0.000
S00.8 Superficial injury of other parts of head	0.007	0.993	0.000
S09.8 Other specified injuries of head	0.007	0.993	0.000
S97.1 Crushing injury of toe(s)	0.007	0.993	0.000
S97.0 Crushing injury of ankle	0.007	0.993	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.007	0.993	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.993	0.007
S06.40 Epidural haemorrhage (without open intracranial wound)	0.007	0.993	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.007	0.993	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.006	0.993	0.000
S94.8 Injury of other nerves at ankle and foot level	0.006	0.993	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.006	0.993	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.006	0.993	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.006	0.993	0.000
S94.1 Injury of medial plantar nerve	0.006	0.993	0.000
S94.0 Injury of lateral plantar nerve	0.006	0.993	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.006	0.993	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.006	0.993	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.006	0.993	0.000
S95.2 Injury of dorsal vein of foot	0.006	0.993	0.000
S95.1 Injury of plantar artery of foot	0.006	0.993	0.000
S95.0 Injury of dorsal artery of foot	0.006	0.993	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.006	0.993	0.000
S98.3 Traumatic amputation of other parts of foot	0.006	0.993	0.000
S98.2 Traumatic amputation of two or more toes	0.006	0.993	0.000
S98.1 Traumatic amputation of one toe	0.006	0.993	0.000
S98.0 Traumatic amputation of foot at ankle level	0.006	0.993	0.000
T62 Toxic effect of other noxious substances eaten as food	0.007	0.993	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.007	0.993	0.000
T60 Toxic effect of pesticides	0.007	0.993	0.000
T57 Toxic effect of other inorganic substances	0.007	0.993	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.007	0.993	0.000
T52 Toxic effect of organic solvents	0.007	0.993	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.007	0.993	0.000
T55 Toxic effect of soaps and detergents	0.007	0.993	0.000
T16 Foreign body in ear	0.007	0.993	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.007	0.993	0.000
T02.41 Fractures involving multiple regions of both upper limbs (open)	0.006	0.993	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.007	0.993	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.007	0.993	0.000
S09.7 Multiple injuries of head	0.006	0.993	0.000
S09.2 Traumatic rupture of ear drum	0.006	0.993	0.000
S09.1 Injury of muscle and tendon of head	0.006	0.993	0.000
T63 Toxic effect of contact with venomous animals	0.007	0.993	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.993	0.007
N03.8 Other	0.006	0.993	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.006	0.993	0.000
N03.6 Dense deposit disease	0.006	0.993	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.993	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.993	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.993	0.000
N03.2 Diffuse membranous glomerulonephritis	0.006	0.993	0.000
N03.0 Minor glomerular abnormality	0.006	0.993	0.000
T65 Toxic effect of other and unspecified substances	0.006	0.993	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.006	0.993	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.006	0.993	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.006	0.993	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
Z48.9 Surgical follow-up care, unspecified	0.000	0.994	0.006
Z48 Other surgical follow-up care	0.000	0.994	0.006
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.006	0.994	0.000
Q05.9 Spina bifida, unspecified	0.006	0.994	0.000
M06 Other rheumatoid arthritis	0.006	0.994	0.000
S50-S59 Injuries to the elbow and forearm	0.006	0.994	0.000
N01.9 Unspecified	0.006	0.994	0.000
N01.8 Other	0.006	0.994	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N01.6 Dense deposit disease	0.006	0.994	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.994	0.000
N01.2 Diffuse membranous glomerulonephritis	0.006	0.994	0.000
N01.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N01.0 Minor glomerular abnormality	0.006	0.994	0.000
N06.9 Unspecified	0.006	0.994	0.000
N06.8 Other	0.006	0.994	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N06.6 Dense deposit disease	0.006	0.994	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.994	0.000
N06.2 Diffuse membranous glomerulonephritis	0.006	0.994	0.000
N06.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N06.0 Minor glomerular abnormality	0.006	0.994	0.000
N07.9 Unspecified	0.006	0.994	0.000
N07.8 Other	0.006	0.994	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N07.6 Dense deposit disease	0.006	0.994	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.994	0.000
N07.2 Diffuse membranous glomerulonephritis	0.006	0.994	0.000
N07.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N07.0 Minor glomerular abnormality	0.006	0.994	0.000
T51.9 Alcohol, unspecified	0.006	0.994	0.000
O42 Premature rupture of membranes	0.006	0.994	0.000
S80-S89 Injuries to the knee and lower leg	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.006	0.994	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.006	0.994	0.000
T18 Foreign body in alimentary tract	0.006	0.994	0.000
T15 Foreign body on external eye	0.006	0.994	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.006	0.994	0.000
T66-T78 Other and unspecified effects of external causes	0.006	0.994	0.000
S11 Open wound of neck	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.006	0.994	0.000
M06.3 Rheumatoid nodule	0.006	0.994	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.006	0.994	0.000
N03.9 Unspecified	0.006	0.994	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.006	0.994	0.000
T02.51 Fractures involving multiple regions of both lower limbs (open)	0.006	0.994	0.000
S93.40 Sprain of unspecified ligament of ankle	0.006	0.994	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.006	0.994	0.000
E04.9 Non-toxic goitre, unspecified	0.006	0.994	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.006	0.994	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.006	0.994	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.006	0.994	0.000
S92.31 Fracture of metatarsal bone (open)	0.006	0.994	0.000
T50.8 Diagnostic agents	0.006	0.994	0.000
T50.7 Analeptics and opioid receptor antagonists	0.006	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
T50.5 Appetite depressants	0.006	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.006	0.994	0.000
T50.1 Loop [high-ceiling] diuretics	0.006	0.994	0.000
T50.0 Mineralocorticoids and their antagonists	0.006	0.994	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.006	0.994	0.000
S14 Injury of nerves and spinal cord at neck level	0.006	0.994	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.006	0.994	0.000
S86 Injury of muscle and tendon at lower leg level	0.006	0.994	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.006	0.994	0.000
S90 Superficial injury of ankle and foot	0.006	0.994	0.000
T54.9 Corrosive substance, unspecified	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.006	0.994	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.005	0.994	0.000
T17.3 Foreign body in larynx	0.006	0.994	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.006	0.994	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
T59 Toxic effect of other gases, fumes and vapours	0.006	0.994	0.000
T01.8 Open wounds involving other combinations of body regions	0.006	0.994	0.000
S91.1 Open wound of toe(s) without damage to nail	0.005	0.994	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.006	0.994	0.000
N05.1 Focal and segmental glomerular lesions	0.005	0.994	0.000
S06.2 Diffuse brain injury	0.005	0.994	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.006	0.994	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.005	0.994	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.006	0.994	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.006	0.994	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.005	0.994	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.005	0.994	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.005	0.994	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.005	0.994	0.000
T11 Other injuries of upper limb, level unspecified	0.006	0.994	0.000
S06.8 Other intracranial injuries	0.005	0.994	0.000
T17.2 Foreign body in pharynx	0.006	0.994	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.005	0.994	0.000
T80.6 Other serum reactions	0.005	0.994	0.000
T80.5 Anaphylactic shock due to serum	0.005	0.994	0.000
T80.4 Rh incompatibility reaction	0.005	0.994	0.000
T80.3 ABO incompatibility reaction	0.005	0.994	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.005	0.994	0.000
T36 Poisoning by systemic antibiotics	0.005	0.994	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.006	0.994	0.000
T19.2 Foreign body in vulva and vagina	0.005	0.994	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.006	0.994	0.000
T83.2 Mechanical complication of graft of urinary organ	0.005	0.994	0.000
T19.1 Foreign body in bladder	0.005	0.994	0.000
S52.10 Fracture of upper end of radius (closed)	0.005	0.995	0.000
T51.8 Other alcohols	0.005	0.995	0.000
T51.3 Fusel oil	0.005	0.995	0.000
T51.2 2-Propanol	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations