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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs289004
log Bayes Factor = 8.50201
Chromosome 5   position 55,684,799  (GRCh37) Explore rs289004 on Ensembl!
Variant rs289004 is part of Cluster X0080

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
Chapter XXI Factors influencing health status and contact with health services
0.986 0.014 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.984 0.016 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.982 0.018 0.000
M45-M49 Spondylopathies
0.976 0.024 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.976 0.024 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.975 0.025 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.975 0.025 0.000
M47 Spondylosis
0.974 0.026 0.000
E65-E68 Obesity and other hyperalimentation
0.973 0.027 0.000
E66 Obesity
0.968 0.032 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.968 0.032 0.000
M47.9 Spondylosis, unspecified
0.960 0.040 0.000
Chapter XX External causes of morbidity and mortality
0.958 0.042 0.000
E66.9 Obesity, unspecified
0.955 0.045 0.000
G35 Multiple sclerosis
0.955 0.045 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.952 0.048 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.952 0.048 0.000
Chapter II Neoplasms
0.949 0.051 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.944 0.056 0.000
S20-S29 Injuries to the thorax
0.943 0.057 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.940 0.060 0.000
E20-E35 Disorders of other endocrine glands
0.938 0.062 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.935 0.065 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.930 0.070 0.000
M47.8 Other spondylosis
0.928 0.072 0.000
M47.82 Other spondylosis (Cervical region)
0.918 0.082 0.000
O36 Maternal care for other known or suspected foetal problems
0.918 0.082 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.918 0.082 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.916 0.084 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.915 0.085 0.000
S10-S19 Injuries to the neck
0.906 0.094 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.906 0.094 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.903 0.097 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.900 0.100 0.000
Z43 Attention to artificial openings
0.897 0.103 0.000
S90-S99 Injuries to the ankle and foot
0.897 0.103 0.000
D50-D53 Nutritional anaemias
0.896 0.104 0.000
Z60 Problems related to social environment
0.896 0.104 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.893 0.107 0.000
Z40 Prophylactic surgery
0.892 0.108 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.890 0.110 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.889 0.111 0.000
O36.8 Maternal care for other specified foetal problems
0.888 0.112 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.883 0.117 0.000
C64-C68 Malignant neoplasms of urinary tract
0.881 0.119 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.881 0.119 0.000
O85-O92 Complications predominantly related to the puerperium
0.876 0.124 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.874 0.126 0.000
Chapter VIII Diseases of the ear and mastoid process
0.874 0.126 0.000
S32 Fracture of lumbar spine and pelvis
0.867 0.133 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.866 0.134 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.865 0.135 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.863 0.137 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.863 0.137 0.000
G40-G47 Episodic and paroxysmal disorders
0.862 0.138 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.861 0.139 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.861 0.139 0.000
Z74 Problems related to care-provider dependency
0.859 0.140 0.000
M80-M85 Disorders of bone density and structure
0.858 0.142 0.000
Z60.2 Living alone
0.856 0.144 0.000
M48 Other spondylopathies
0.855 0.145 0.000
D51 Vitamin B12 deficiency anaemia
0.853 0.147 0.000
C34 Malignant neoplasm of bronchus and lung
0.853 0.147 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.852 0.148 0.000
Z72 Problems related to lifestyle
0.850 0.150 0.000
Z57 Occupational exposure to risk-factors
0.850 0.150 0.000
G40 Epilepsy
0.846 0.154 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.845 0.155 0.000
Z45 Adjustment and management of implanted device
0.843 0.157 0.000
G37 Other demyelinating diseases of central nervous system
0.842 0.158 0.000
Chapter VII Diseases of the eye and adnexa
0.838 0.162 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.836 0.164 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.834 0.166 0.000
E66.8 Other obesity
0.834 0.166 0.000
Chapter XIV Diseases of the genitourinary system
0.832 0.168 0.000
C34.1 Upper lobe, bronchus or lung
0.831 0.169 0.000
Z49 Care involving dialysis
0.830 0.170 0.000
H25-H28 Disorders of lens
0.828 0.172 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.828 0.172 0.000
O36.5 Maternal care for poor foetal growth
0.828 0.172 0.000
O48 Prolonged pregnancy
0.827 0.173 0.000
H26 Other cataract
0.826 0.174 0.000
S60-S69 Injuries to the wrist and hand
0.826 0.174 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.825 0.175 0.000
Z71.3 Dietary counselling and surveillance
0.823 0.177 0.000
N20-N23 Urolithiasis
0.822 0.178 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.819 0.181 0.000
M86-M90 Other osteopathies
0.818 0.182 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.817 0.183 0.000
Z72.0 Tobacco use
0.815 0.185 0.000
H65-H75 Diseases of middle ear and mastoid
0.815 0.185 0.000
S50-S59 Injuries to the elbow and forearm
0.814 0.186 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.813 0.187 0.000
H26.9 Cataract, unspecified
0.813 0.187 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.808 0.192 0.000
G40.9 Epilepsy, unspecified
0.805 0.195 0.000
S27 Injury of other and unspecified intrathoracic organs
0.804 0.196 0.000
C79 Secondary malignant neoplasm of other sites
0.804 0.196 0.000
N21 Calculus of lower urinary tract
0.804 0.196 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.802 0.198 0.000
S12 Fracture of neck
0.801 0.199 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.795 0.205 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.793 0.207 0.000
Z47 Other orthopaedic follow-up care
0.793 0.207 0.000
N10-N16 Renal tubulo-interstitial diseases
0.792 0.208 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.790 0.210 0.000
G70-G73 Diseases of myoneural junction and muscle
0.790 0.210 0.000
M40-M43 Deforming dorsopathies
0.788 0.212 0.000
E23 Hypofunction and other disorders of pituitary gland
0.785 0.215 0.000
S22.3 Fracture of rib
0.785 0.215 0.000
Q60-Q64 Congenital malformations of the urinary system
0.783 0.217 0.000
N21.0 Calculus in bladder
0.781 0.219 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.780 0.220 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.779 0.221 0.000
D50 Iron deficiency anaemia
0.778 0.222 0.000
H26.4 After-cataract
0.777 0.223 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.776 0.224 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.776 0.224 0.000
Z54 Convalescence
0.775 0.225 0.000
T66-T78 Other and unspecified effects of external causes
0.775 0.225 0.000
W20-W49 Exposure to inanimate mechanical forces
0.774 0.226 0.000
Y40 Systemic antibiotics
0.773 0.227 0.000
M48.0 Spinal stenosis
0.773 0.227 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.771 0.229 0.000
O90 Complications of the puerperium, not elsewhere classified
0.771 0.229 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.770 0.230 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.769 0.231 0.000
D37.4 Colon
0.769 0.231 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.768 0.232 0.000
E40-E46 Malnutrition
0.767 0.233 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.766 0.234 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.765 0.234 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.764 0.236 0.000
M45 Ankylosing spondylitis
0.764 0.236 0.000
X50-X57 Overexertion, travel and privation
0.762 0.238 0.000
E29 Testicular dysfunction
0.757 0.243 0.000
E26 Hyperaldosteronism
0.757 0.243 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.754 0.246 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.753 0.247 0.000
S80-S89 Injuries to the knee and lower leg
0.752 0.248 0.000
N20 Calculus of kidney and ureter
0.752 0.248 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.750 0.250 0.000
M47.2 Other spondylosis with radiculopathy
0.749 0.251 0.000
V20-V29 Motorcycle rider injured in transport accident
0.749 0.251 0.000
M49 Spondylopathies in diseases classified elsewhere
0.748 0.251 0.000
T86 Failure and rejection of transplanted organs and tissues
0.748 0.252 0.000
M47.1 Other spondylosis with myelopathy
0.748 0.252 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.748 0.252 0.000
S32.1 Fracture of sacrum
0.747 0.253 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.747 0.253 0.000
D50.9 Iron deficiency anaemia, unspecified
0.746 0.254 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.744 0.256 0.000
T51 Toxic effect of alcohol
0.744 0.256 0.000
D60-D64 Aplastic and other anaemias
0.743 0.257 0.000
E34 Other endocrine disorders
0.742 0.258 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.741 0.258 0.000
Z43.1 Attention to gastrostomy
0.741 0.259 0.000
S19 Other and unspecified injuries of neck
0.741 0.259 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.741 0.259 0.000
M60-M63 Disorders of muscles
0.740 0.260 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.739 0.261 0.000
Z45.8 Adjustment and management of other implanted devices
0.739 0.261 0.000
S90 Superficial injury of ankle and foot
0.737 0.263 0.000
S32.5 Fracture of pubis
0.736 0.264 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.735 0.265 0.000
S36 Injury of intra-abdominal organs
0.735 0.265 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.734 0.266 0.000
M85 Other disorders of bone density and structure
0.732 0.268 0.000
Y44 Agents primarily affecting blood constituents
0.732 0.268 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.732 0.268 0.000
E21.0 Primary hyperparathyroidism
0.732 0.268 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.731 0.269 0.000
T87 Complications peculiar to reattachment and amputation
0.731 0.269 0.000
M46 Other inflammatory spondylopathies
0.730 0.270 0.000
S91 Open wound of ankle and foot
0.730 0.270 0.000
Y45.2 Propionic acid derivatives
0.729 0.271 0.000
M48.02 Spinal stenosis (Cervical region)
0.728 0.272 0.000
M47.89 Other spondylosis (Site unspecified)
0.728 0.272 0.000
H26.1 Traumatic cataract
0.727 0.273 0.000
N13 Obstructive and reflux uropathy
0.727 0.273 0.000
S22.4 Multiple fractures of ribs
0.727 0.273 0.000
E00-E07 Disorders of thyroid gland
0.727 0.273 0.000
S22.30 Fracture of rib (closed)
0.727 0.273 0.000
Z74.0 Reduced mobility
0.727 0.273 0.000
N20.1 Calculus of ureter
0.726 0.274 0.000
M00-M03 Infectious arthropathies
0.726 0.274 0.000
O47 False labour
0.725 0.275 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.722 0.278 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.721 0.279 0.000
W50-W64 Exposure to animate mechanical forces
0.719 0.281 0.000
H66 Suppurative and unspecified otitis media
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z71.8 Other specified counselling
0.717 0.283 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.717 0.283 0.000
Z74.9 Problem related to care-provider dependency, unspecified
0.717 0.283 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.716 0.284 0.000
H74 Other disorders of middle ear and mastoid
0.714 0.286 0.000
Z57.3 Occupational exposure to other air contaminants
0.714 0.286 0.000
O23 Infections of genito-urinary tract in pregnancy
0.711 0.289 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.710 0.290 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.710 0.290 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.709 0.291 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.707 0.292 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.707 0.293 0.000
Y57 Other and unspecified drugs and medicaments
0.706 0.294 0.000
S92 Fracture of foot, except ankle
0.706 0.294 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.706 0.294 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.705 0.295 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.705 0.295 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.705 0.295 0.000
G30-G32 Other degenerative diseases of the nervous system
0.703 0.296 0.000
C67 Malignant neoplasm of bladder
0.704 0.296 0.000
D37.5 Rectum
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.297 0.000
Z71.2 Person consulting for explanation of investigation findings
0.703 0.297 0.000
Z43.8 Attention to other artificial openings
0.702 0.298 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.702 0.298 0.000
T79-T79 Certain early complications of trauma
0.701 0.299 0.000
Z49.0 Preparatory care for dialysis
0.701 0.299 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.700 0.300 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.699 0.300 0.000
T83.2 Mechanical complication of graft of urinary organ
0.699 0.300 0.000
G36 Other acute disseminated demyelination
0.699 0.301 0.000
T59 Toxic effect of other gases, fumes and vapours
0.699 0.301 0.000
E22 Hyperfunction of pituitary gland
0.699 0.301 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.698 0.302 0.000
Chapter XXII Codes for special purposes
0.698 0.302 0.000
E67 Other hyperalimentation
0.698 0.302 0.000
E68 Sequelae of hyperalimentation
0.698 0.302 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.697 0.303 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.697 0.303 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.696 0.304 0.000
D45 Polycythaemia vera
0.696 0.304 0.000
G20-G26 Extrapyramidal and movement disorders
0.696 0.304 0.000
O90.8 Other complications of the puerperium, not elsewhere classified
0.695 0.304 0.000
T63 Toxic effect of contact with venomous animals
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.695 0.305 0.000
D55-D59 Haemolytic anaemias
0.695 0.305 0.000
E66.1 Drug-induced obesity
0.694 0.306 0.000
E66.0 Obesity due to excess calories
0.694 0.306 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.694 0.306 0.000
X60-X84 Intentional self-harm
0.694 0.306 0.000
O86 Other puerperal infections
0.693 0.307 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.691 0.309 0.000
S70-S79 Injuries to the hip and thigh
0.689 0.310 0.000
Z52 Donors of organs and tissues
0.689 0.311 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.689 0.311 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.688 0.312 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.688 0.312 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.688 0.312 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.688 0.312 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.688 0.312 0.000
M91-M94 Chondropathies
0.688 0.312 0.000
O44 Placenta praevia
0.687 0.313 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.687 0.313 0.000
Y00-Y09 Assault
0.687 0.313 0.000
X85-X99 Assault
0.687 0.313 0.000
X30-X39 Exposure to forces of nature
0.687 0.313 0.000
X10-X19 Contact with heat and hot substances
0.687 0.313 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.313 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
W75-W84 Other accidental threats to breathing
0.687 0.313 0.000
W65-W74 Accidental drowning and submersion
0.687 0.313 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.313 0.000
V95-V97 Air and space transport accidents
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.313 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.313 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.313 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.313 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.313 0.000
O00-O08 Pregnancy with abortive outcome
0.684 0.316 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.684 0.316 0.000
C79.2 Secondary malignant neoplasm of skin
0.684 0.316 0.000
M84 Disorders of continuity of bone
0.683 0.317 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.683 0.317 0.000
Z65 Problems related to other psychosocial circumstances
0.682 0.318 0.000
Z64 Problems related to certain psychosocial circumstances
0.682 0.318 0.000
Z62 Other problems related to upbringing
0.682 0.318 0.000
Z61 Problems related to negative life events in childhood
0.682 0.318 0.000
Z59 Problems related to housing and economic circumstances
0.682 0.318 0.000
Z58 Problems related to physical environment
0.682 0.318 0.000
Z56 Problems related to employment and unemployment
0.682 0.318 0.000
Z55 Problems related to education and literacy
0.682 0.318 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.682 0.318 0.000
S37 Injury of urinary and pelvic organs
0.682 0.318 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.682 0.318 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.682 0.318 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.682 0.318 0.000
S31 Open wound of abdomen, lower back and pelvis
0.682 0.318 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.681 0.319 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.681 0.319 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.681 0.319 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.681 0.319 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.680 0.320 0.000
S29 Other and unspecified injuries of thorax
0.679 0.320 0.000
G90-G99 Other disorders of the nervous system
0.679 0.321 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.678 0.321 0.000
Q50-Q56 Congenital malformations of genital organs
0.678 0.322 0.000
Z72.2 Drug use
0.678 0.322 0.000
Z42 Follow-up care involving plastic surgery
0.678 0.322 0.000
H71 Cholesteatoma of middle ear
0.677 0.323 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.677 0.323 0.000
O20 Haemorrhage in early pregnancy
0.677 0.323 0.000
Y45.0 Opioids and related analgesics
0.677 0.323 0.000
O45 Premature separation of placenta [abruptio placentae]
0.677 0.323 0.000
O33 Maternal care for known or suspected disproportion
0.677 0.323 0.000
O31 Complications specific to multiple gestation
0.677 0.323 0.000
T58 Toxic effect of carbon monoxide
0.676 0.323 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.676 0.324 0.000
S26 Injury of heart
0.676 0.324 0.000
S25 Injury of blood vessels of thorax
0.676 0.324 0.000
S24 Injury of nerves and spinal cord at thorax level
0.676 0.324 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.676 0.324 0.000
S21 Open wound of thorax
0.676 0.324 0.000
D46 Myelodysplastic syndromes
0.676 0.324 0.000
E23.0 Hypopituitarism
0.675 0.325 0.000
N21.1 Calculus in urethra
0.675 0.325 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.674 0.326 0.000
O43 Placental disorders
0.674 0.326 0.000
Z44 Fitting and adjustment of external prosthetic device
0.674 0.326 0.000
S12.2 Fracture of other specified cervical vertebra
0.673 0.327 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.673 0.327 0.000
C34.3 Lower lobe, bronchus or lung
0.673 0.327 0.000
Z76 Persons encountering health services in other circumstances
0.673 0.327 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.672 0.327 0.000
E32 Diseases of thymus
0.672 0.327 0.000
E31 Polyglandular dysfunction
0.672 0.327 0.000
E30 Disorders of puberty, not elsewhere classified
0.672 0.327 0.000
E25 Adrenogenital disorders
0.672 0.327 0.000
E20 Hypoparathyroidism
0.672 0.327 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.672 0.327 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.672 0.328 0.000
T23 Burn and corrosion of wrist and hand
0.672 0.328 0.000
X20-X29 Contact with venomous animals and plants
0.672 0.328 0.000
E21.3 Hyperparathyroidism, unspecified
0.671 0.329 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.671 0.329 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.671 0.329 0.000
S67 Crushing injury of wrist and hand
0.670 0.330 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.670 0.330 0.000
M81 Osteoporosis without pathological fracture
0.670 0.330 0.000
T81 Complications of procedures, not elsewhere classified
0.669 0.331 0.000
Q80-Q89 Other congenital malformations
0.668 0.331 0.000
S12.1 Fracture of second cervical vertebra
0.668 0.332 0.000
S30.0 Contusion of lower back and pelvis
0.668 0.332 0.000
T39.0 Salicylates
0.668 0.332 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.668 0.332 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.667 0.333 0.000
C65 Malignant neoplasm of renal pelvis
0.667 0.333 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.333 0.000
Y58 Bacterial vaccines
0.667 0.333 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.333 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.333 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.667 0.333 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.667 0.333 0.000
S20 Superficial injury of thorax
0.666 0.333 0.000
S22.5 Flail chest
0.666 0.334 0.000
N99-N99 Other disorders of the genitourinary system
0.666 0.334 0.000
Chapter V Mental and behavioural disorders
0.666 0.334 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.665 0.335 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.665 0.335 0.000
M47.84 Other spondylosis (Thoracic region)
0.665 0.335 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.665 0.335 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.665 0.335 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.664 0.336 0.000
O36.4 Maternal care for intra-uterine death
0.663 0.337 0.000
Z75 Problems related to medical facilities and other health care
0.663 0.337 0.000
S32.10 Fracture of sacrum (closed)
0.662 0.338 0.000
M89 Other disorders of bone
0.662 0.338 0.000
E65 Localised adiposity
0.661 0.339 0.000
O40 Polyhydramnios
0.661 0.339 0.000
S54 Injury of nerves at forearm level
0.659 0.341 0.000
Z47.8 Other specified orthopaedic follow-up care
0.659 0.341 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.658 0.342 0.000
O36.2 Maternal care for hydrops foetalis
0.658 0.342 0.000
O36.1 Maternal care for other isoimmunisation
0.658 0.342 0.000
Z71.7 Human immunodeficiency virus [HIV] counselling
0.658 0.342 0.000
Z71.6 Tobacco abuse counselling
0.658 0.342 0.000
Z71.5 Drug abuse counselling and surveillance
0.658 0.342 0.000
Z71.4 Alcohol abuse counselling and surveillance
0.658 0.342 0.000
Z71.0 Person consulting on behalf of another person
0.658 0.342 0.000
O41 Other disorders of amniotic fluid and membranes
0.658 0.342 0.000
Z54.0 Convalescence following surgery
0.656 0.344 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
O97 Death from sequelae of direct obstetric causes
0.656 0.344 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.656 0.344 0.000
O95 Obstetric death of unspecified cause
0.656 0.344 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.656 0.344 0.000
S82 Fracture of lower leg, including ankle
0.655 0.345 0.000
O30 Multiple gestation
0.655 0.345 0.000
T40.2 Other opioids
0.655 0.345 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.654 0.346 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.653 0.347 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.653 0.347 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.653 0.347 0.000
S27.0 Traumatic pneumothorax
0.652 0.348 0.000
H60-H62 Diseases of external ear
0.652 0.348 0.000
M85.8 Other specified disorders of bone density and structure
0.652 0.348 0.000
Z71.9 Counselling, unspecified
0.651 0.349 0.000
S56 Injury of muscle and tendon at forearm level
0.651 0.349 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.650 0.350 0.000
Z49.1 Extracorporeal dialysis
0.650 0.350 0.000
S17 Crushing injury of neck
0.650 0.350 0.000
S15 Injury of blood vessels at neck level
0.650 0.350 0.000
S14 Injury of nerves and spinal cord at neck level
0.650 0.350 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.650 0.350 0.000
S11 Open wound of neck
0.650 0.350 0.000
S10 Superficial injury of neck
0.650 0.350 0.000
S18 Traumatic amputation at neck level
0.650 0.350 0.000
S16 Injury of muscle and tendon at neck level
0.650 0.350 0.000
T39.1 4-Aminophenol derivatives
0.649 0.351 0.000
N13.3 Other and unspecified hydronephrosis
0.649 0.351 0.000
H49 Paralytic strabismus
0.648 0.352 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.647 0.353 0.000
Y45.8 Other analgesics and antipyretics
0.647 0.353 0.000
Y45.5 4-Aminophenol derivatives
0.647 0.353 0.000
Y45.4 Antirheumatics
0.647 0.353 0.000
Y95 Nosocomial condition
0.646 0.354 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.646 0.354 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.645 0.355 0.000
Q35-Q37 Cleft lip and cleft palate
0.645 0.355 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.645 0.355 0.000
C80 Malignant neoplasm without specification of site
0.645 0.355 0.000
S50 Superficial injury of forearm
0.645 0.355 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.644 0.356 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.644 0.356 0.000
M65-M68 Disorders of synovium and tendon
0.644 0.356 0.000
Z43.9 Attention to unspecified artificial opening
0.643 0.357 0.000
Z43.7 Attention to artificial vagina
0.643 0.357 0.000
Z43.5 Attention to cyctostomy
0.643 0.357 0.000
Z43.0 Attention to tracheostomy
0.643 0.357 0.000
S98 Traumatic amputation of ankle and foot
0.643 0.357 0.000
S97 Crushing injury of ankle and foot
0.643 0.357 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.643 0.357 0.000
S95 Injury of blood vessels at ankle and foot level
0.643 0.357 0.000
S94 Injury of nerves at ankle and foot level
0.643 0.357 0.000
E05.9 Thyrotoxicosis, unspecified
0.643 0.357 0.000
M40 Kyphosis and lordosis
0.643 0.357 0.000
D53 Other nutritional anaemias
0.642 0.358 0.000
Z60.9 Problem related to social environment, unspecified
0.642 0.358 0.000
Z60.8 Other problems related to social environment
0.642 0.358 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.642 0.358 0.000
Z60.4 Social exclusion and rejection
0.642 0.358 0.000
Z60.3 Acculturation difficulty
0.642 0.358 0.000
Z60.1 Atypical parenting situation
0.642 0.358 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.642 0.358 0.000
Z49.2 Other dialysis
0.642 0.358 0.000
Y43 Primarily systemic agents
0.642 0.358 0.000
S32.50 Fracture of pubis (closed)
0.642 0.358 0.000
S32.3 Fracture of ilium
0.642 0.358 0.000
M88 Paget's disease of bone [osteitis deformans]
0.641 0.358 0.000
C66 Malignant neoplasm of ureter
0.641 0.359 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.641 0.359 0.000
Z63 Other problems related to primary support group, including family circumstances
0.641 0.359 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.640 0.359 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.640 0.360 0.000
T65 Toxic effect of other and unspecified substances
0.640 0.360 0.000
T62 Toxic effect of other noxious substances eaten as food
0.640 0.360 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.640 0.360 0.000
T60 Toxic effect of pesticides
0.640 0.360 0.000
T57 Toxic effect of other inorganic substances
0.640 0.360 0.000
T56 Toxic effect of metals
0.640 0.360 0.000
T54 Toxic effect of corrosive substances
0.640 0.360 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.640 0.360 0.000
T52 Toxic effect of organic solvents
0.640 0.360 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.640 0.360 0.000
T55 Toxic effect of soaps and detergents
0.640 0.360 0.000
Z40.9 Prophylactic surgery, unspecified
0.640 0.360 0.000
N25-N29 Other disorders of kidney and ureter
0.640 0.360 0.000
H52 Disorders of refraction and accommodation
0.639 0.361 0.000
T98 Sequelae of other and unspecified effects of external causes
0.638 0.361 0.000
G40.5 Special epileptic syndromes
0.638 0.362 0.000
O46.9 Antepartum haemorrhage, unspecified
0.638 0.362 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.638 0.362 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.638 0.362 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.638 0.362 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.638 0.362 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.638 0.362 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.638 0.362 0.000
T36 Poisoning by systemic antibiotics
0.638 0.362 0.000
O36.6 Maternal care for excessive foetal growth
0.638 0.362 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.638 0.362 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.638 0.362 0.000
C31 Malignant neoplasm of accessory sinuses
0.638 0.362 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.638 0.362 0.000
C37 Malignant neoplasm of thymus
0.638 0.362 0.000
C33 Malignant neoplasm of trachea
0.638 0.362 0.000
N11 Chronic tubulo-interstitial nephritis
0.637 0.363 0.000
Z41 Procedures for purposes other than remedying health state
0.636 0.363 0.000
S27.3 Other injuries of lung
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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