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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2915695
log Bayes Factor = 10.927
Chromosome 15   position 78,739,471  (GRCh37) Explore rs2915695 on Ensembl!
Variant rs2915695 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
I71 Aortic aneurysm and dissection
1.000 0.000 0.000
I69 Sequelae of cerebrovascular disease
0.999 0.001 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.995 0.005 0.000
I67 Other cerebrovascular diseases
0.995 0.005 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.992 0.008 0.000
I73 Other peripheral vascular diseases
0.992 0.008 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.991 0.009 0.000
I60 Subarachnoid haemorrhage
0.990 0.010 0.000
I73.9 Peripheral vascular disease, unspecified
0.984 0.016 0.000
I70 Atherosclerosis
0.983 0.017 0.000
I67.9 Cerebrovascular disease, unspecified
0.980 0.020 0.000
J40-J47 Chronic lower respiratory diseases
0.980 0.020 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.976 0.024 0.000
J43 Emphysema
0.975 0.025 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.973 0.027 0.000
J43.9 Emphysema, unspecified
0.973 0.027 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.965 0.035 0.000
J42 Unspecified chronic bronchitis
0.961 0.039 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.954 0.046 0.000
I67.1 Cerebral aneurysm, nonruptured
0.947 0.053 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.946 0.054 0.000
I60.8 Other subarachnoid haemorrhage
0.933 0.067 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.930 0.070 0.000
I69.3 Sequelae of cerebral infarction
0.926 0.074 0.000
I77 Other disorders of arteries and arterioles
0.900 0.100 0.000
Chapter IX Diseases of the circulatory system
0.891 0.109 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.882 0.118 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.876 0.124 0.000
I72 Other aneurysm
0.873 0.127 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.866 0.134 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.850 0.150 0.000
I73.0 Raynaud's syndrome
0.832 0.168 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.827 0.173 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.821 0.179 0.000
I67.8 Other specified cerebrovascular diseases
0.821 0.179 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.819 0.181 0.000
I74 Arterial embolism and thrombosis
0.814 0.186 0.000
I70.8 Atherosclerosis of other arteries
0.810 0.190 0.000
I77.0 Arteriovenous fistula, acquired
0.803 0.197 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.785 0.215 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.785 0.215 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.781 0.219 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.778 0.222 0.000
I70.0 Atherosclerosis of aorta
0.771 0.229 0.000
J41 Simple and mucopurulent chronic bronchitis
0.771 0.229 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.768 0.232 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.765 0.235 0.000
I72.8 Aneurysm of other specified arteries
0.757 0.243 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.755 0.245 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.739 0.261 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.735 0.265 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.724 0.276 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.723 0.277 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.717 0.283 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.717 0.283 0.000
I67.5 Moyamoya disease
0.713 0.286 0.000
I67.3 Progressive vascular leukoencephalopathy
0.713 0.286 0.000
I61 Intracerebral haemorrhage
0.711 0.289 0.000
I72.0 Aneurysm of carotid artery
0.710 0.290 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.710 0.290 0.000
J43.2 Centrilobular emphysema
0.710 0.290 0.000
I67.4 Hypertensive encephalopathy
0.700 0.300 0.000
J43.1 Panlobular emphysema
0.699 0.301 0.000
J43.0 MacLeod's syndrome
0.699 0.301 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.697 0.303 0.000
I71.0 Dissection of aorta [any part]
0.692 0.308 0.000
I72.9 Aneurysm of unspecified site
0.689 0.311 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.685 0.315 0.000
I70.9 Generalised and unspecified atherosclerosis
0.682 0.318 0.000
I77.2 Rupture of artery
0.677 0.323 0.000
I77.1 Stricture of artery
0.677 0.323 0.000
I78 Diseases of capillaries
0.668 0.332 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.666 0.333 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.665 0.335 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.662 0.338 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.656 0.344 0.000
I72.4 Aneurysm of artery of lower extremity
0.651 0.349 0.000
I72.1 Aneurysm of artery of upper extremity
0.647 0.353 0.000
I77.5 Necrosis of artery
0.645 0.355 0.000
I77.4 Coeliac artery compression syndrome
0.645 0.355 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.639 0.361 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.635 0.365 0.000
I63 Cerebral infarction
0.634 0.366 0.000
I70.1 Atherosclerosis of renal artery
0.633 0.366 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.627 0.373 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.626 0.374 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.622 0.378 0.000
J43.8 Other emphysema
0.621 0.379 0.000
J41.0 Simple chronic bronchitis
0.621 0.379 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.618 0.381 0.000
I00-I02 Acute rheumatic fever
0.616 0.383 0.000
I74.8 Embolism and thrombosis of other arteries
0.615 0.385 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.615 0.385 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.612 0.388 0.000
I27 Other pulmonary heart diseases
0.604 0.396 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.591 0.409 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.586 0.414 0.000
I27.9 Pulmonary heart disease, unspecified
0.584 0.416 0.000
E11 Non-insulin-dependent diabetes mellitus
0.584 0.416 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.582 0.418 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.580 0.419 0.000
I68.0 Cerebral amyloid angiopathy
0.579 0.421 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.571 0.429 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.567 0.433 0.000
E11.4 With neurological complications
0.563 0.437 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.562 0.438 0.000
E11.3 With ophthalmic complications
0.555 0.445 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.553 0.447 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.553 0.447 0.000
J41.1 Mucopurulent chronic bronchitis
0.553 0.447 0.000
I72.3 Aneurysm of iliac artery
0.552 0.448 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.549 0.451 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.541 0.459 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.541 0.459 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.541 0.459 0.000
E11.5 With peripheral circulatory complications
0.538 0.462 0.000
I72.2 Aneurysm of renal artery
0.532 0.468 0.000
I79.1 Aortitis in diseases classified elsewhere
0.530 0.470 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.530 0.470 0.000
I77.3 Arterial fibromuscular dysplasia
0.529 0.470 0.000
I73.8 Other specified peripheral vascular diseases
0.528 0.471 0.000
I74.5 Embolism and thrombosis of iliac artery
0.524 0.476 0.000
I26 Pulmonary embolism
0.523 0.477 0.000
E11.0 With coma
0.521 0.479 0.000
E11.2 With renal complications
0.519 0.481 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.516 0.484 0.000
E11.8 With unspecified complications
0.511 0.489 0.000
I28 Other diseases of pulmonary vessels
0.510 0.490 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.509 0.491 0.000
E11.6 With other specified complications
0.505 0.495 0.000
I77.8 Other specified disorders of arteries and arterioles
0.503 0.496 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.502 0.498 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.502 0.498 0.000
I62 Other nontraumatic intracranial haemorrhage
0.494 0.506 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.489 0.511 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.486 0.514 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.483 0.517 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.479 0.521 0.000
I61.8 Other intracerebral haemorrhage
0.471 0.528 0.000
Chapter X Diseases of the respiratory system
0.470 0.530 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.469 0.531 0.000
J46 Status asthmaticus
0.468 0.532 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.468 0.532 0.000
I78.9 Disease of capillaries, unspecified
0.467 0.533 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.466 0.534 0.000
E10-E14 Diabetes mellitus
0.466 0.534 0.000
J92.0 Pleural plaque with presence of asbestos
0.465 0.535 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.463 0.537 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.458 0.542 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.458 0.542 0.000
J92 Pleural plaque
0.458 0.542 0.000
I78.8 Other diseases of capillaries
0.457 0.543 0.000
I67.2 Cerebral atherosclerosis
0.456 0.544 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.455 0.545 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.455 0.545 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.454 0.546 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.454 0.546 0.000
J60-J70 Lung diseases due to external agents
0.451 0.549 0.000
J90-J94 Other diseases of pleura
0.450 0.550 0.000
J40 Bronchitis, not specified as acute or chronic
0.443 0.557 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.442 0.558 0.000
I02 Rheumatic chorea
0.442 0.558 0.000
I01 Rheumatic fever with heart involvement
0.442 0.558 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.442 0.558 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.441 0.558 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.440 0.560 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.440 0.560 0.000
E11.1 With ketoacidosis
0.440 0.560 0.000
E11.7 With multiple complications
0.434 0.566 0.000
I27.1 Kyphoscoliotic heart disease
0.433 0.567 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.428 0.572 0.000
I27.8 Other specified pulmonary heart diseases
0.428 0.572 0.000
E14 Unspecified diabetes mellitus
0.422 0.578 0.000
I00 Rheumatic fever without mention of heart involvement
0.419 0.580 0.000
E14.9 Without complications
0.404 0.596 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.401 0.599 0.000
E13 Other specified diabetes mellitus
0.397 0.603 0.000
I05-I09 Chronic rheumatic heart diseases
0.396 0.604 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.393 0.607 0.000
J95-J99 Other diseases of the respiratory system
0.391 0.609 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.390 0.610 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.387 0.613 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.383 0.617 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.380 0.620 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.380 0.620 0.000
J92.9 Pleural plaque without asbestos
0.375 0.625 0.000
I28.1 Aneurysm of pulmonary artery
0.365 0.634 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.365 0.635 0.000
I63.9 Cerebral infarction, unspecified
0.365 0.635 0.000
J60 Coalworker's pneumoconiosis
0.355 0.645 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.354 0.646 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.349 0.651 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.348 0.652 0.000
E13.9 Without complications
0.348 0.652 0.000
I62.1 Nontraumatic extradural haemorrhage
0.346 0.654 0.000
J69 Pneumonitis due to solids and liquids
0.343 0.657 0.000
I28.8 Other specified diseases of pulmonary vessels
0.342 0.658 0.000
J86 Pyothorax
0.341 0.659 0.000
I77.6 Arteritis, unspecified
0.339 0.661 0.000
I27.0 Primary pulmonary hypertension
0.336 0.664 0.000
J64 Unspecified pneumoconiosis
0.335 0.664 0.000
J98 Other respiratory disorders
0.334 0.666 0.000
E12 Malnutrition-related diabetes mellitus
0.334 0.666 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.334 0.666 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.328 0.672 0.000
E10 Insulin-dependent diabetes mellitus
0.326 0.674 0.000
I06 Rheumatic aortic valve diseases
0.325 0.675 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.323 0.677 0.000
J66 Airway disease due to specific organic dust
0.323 0.677 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.323 0.677 0.000
J65 Pneumoconiosis associated with tuberculosis
0.323 0.677 0.000
J62 Pneumoconiosis due to dust containing silica
0.321 0.679 0.000
E14.3 With ophthalmic complications
0.318 0.682 0.000
I09 Other rheumatic heart diseases
0.317 0.683 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.317 0.683 0.000
I01.8 Other acute rheumatic heart disease
0.317 0.683 0.000
I01.2 Acute rheumatic myocarditis
0.317 0.683 0.000
I01.1 Acute rheumatic endocarditis
0.317 0.683 0.000
I01.0 Acute rheumatic pericarditis
0.317 0.683 0.000
I02.9 Rheumatic chorea without heart involvement
0.317 0.683 0.000
I02.0 Rheumatic chorea with heart involvement
0.317 0.683 0.000
E14.0 With coma
0.313 0.687 0.000
J86.9 Pyothorax without fistula
0.312 0.688 0.000
E10.1 With ketoacidosis
0.312 0.688 0.000
E14.1 With ketoacidosis
0.309 0.691 0.000
I65.2 Occlusion and stenosis of carotid artery
0.306 0.694 0.000
J98.1 Pulmonary collapse
0.304 0.696 0.000
J70 Respiratory conditions due to other external agents
0.303 0.696 0.000
E14.7 With multiple complications
0.303 0.697 0.000
E14.8 With unspecified complications
0.302 0.698 0.000
E14.4 With neurological complications
0.298 0.702 0.000
I78.1 Naevus, nonneoplastic
0.298 0.702 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.295 0.705 0.000
J98.9 Respiratory disorder, unspecified
0.290 0.710 0.000
E14.6 With other specified complications
0.287 0.713 0.000
E13.3 With ophthalmic complications
0.286 0.714 0.000
E13.8 With unspecified complications
0.285 0.715 0.000
E13.7 With multiple complications
0.285 0.715 0.000
E13.6 With other specified complications
0.285 0.715 0.000
E13.5 With peripheral circulatory complications
0.285 0.715 0.000
E13.4 With neurological complications
0.285 0.715 0.000
E13.2 With renal complications
0.285 0.715 0.000
E13.1 With ketoacidosis
0.285 0.715 0.000
E13.0 With coma
0.285 0.715 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.285 0.715 0.000
J96 Respiratory failure, not elsewhere classified
0.281 0.719 0.000
I63.8 Other cerebral infarction
0.280 0.720 0.000
J93 Pneumothorax
0.275 0.725 0.000
J69.8 Pneumonitis due to other solids and liquids
0.273 0.727 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.271 0.729 0.000
E14.5 With peripheral circulatory complications
0.269 0.731 0.000
I06.1 Rheumatic aortic insufficiency
0.266 0.733 0.000
J00-J06 Acute upper respiratory infections
0.266 0.734 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.265 0.735 0.000
I65.1 Occlusion and stenosis of basilar artery
0.264 0.735 0.001
I09.9 Rheumatic heart disease, unspecified
0.261 0.739 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.253 0.747 0.000
E14.2 Withrenal complications
0.248 0.752 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.247 0.753 0.000
I07 Rheumatic tricuspid valve diseases
0.247 0.753 0.000
J69.1 Pneumonitis due to oils and essences
0.246 0.754 0.000
J85 Abscess of lung and mediastinum
0.246 0.754 0.000
E10.0 With coma
0.243 0.757 0.000
J45 Asthma
0.243 0.757 0.000
J91 Pleural effusion in conditions classified elsewhere
0.242 0.758 0.000
E10.6 With other specified complications
0.241 0.759 0.000
J98.3 Compensatory emphysema
0.240 0.760 0.000
E12.9 Without complications
0.240 0.760 0.000
E12.8 With unspecified complications
0.240 0.760 0.000
E12.7 With multiple complications
0.240 0.760 0.000
E12.6 With other specified complications
0.240 0.760 0.000
E12.5 With peripheral circulatory complications
0.240 0.760 0.000
E12.4 With neurological complications
0.240 0.760 0.000
E12.3 With ophthalmic complications
0.240 0.760 0.000
E12.2 With renal complications
0.240 0.760 0.000
E12.1 With ketoacidosis
0.240 0.760 0.000
E12.0 With coma
0.240 0.760 0.000
J98.4 Other disorders of lung
0.239 0.761 0.000
J94 Other pleural conditions
0.238 0.762 0.000
J69.0 Pneumonitis due to food and vomit
0.235 0.765 0.000
J93.1 Other spontaneous pneumothorax
0.234 0.766 0.000
J98.2 Interstitial emphysema
0.234 0.766 0.000
I06.8 Other rheumatic aortic valve diseases
0.233 0.767 0.000
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.232 0.768 0.000
J63.5 Stannosis
0.232 0.768 0.000
J63.4 Siderosis
0.232 0.768 0.000
J63.3 Graphite fibrosis (of lung)
0.232 0.768 0.000
J63.2 Berylliosis
0.232 0.768 0.000
J63.1 Bauxite fibrosis (of lung)
0.232 0.768 0.000
J63.0 Aluminosis (of lung)
0.232 0.768 0.000
J66.8 Airway disease due to other specific organic dusts
0.232 0.768 0.000
J66.2 Cannabinosis
0.232 0.768 0.000
J66.1 Flax-dresser's disease
0.232 0.768 0.000
J66.0 Byssinosis
0.232 0.768 0.000
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.232 0.768 0.000
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.232 0.768 0.000
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.232 0.768 0.000
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.232 0.768 0.000
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.232 0.768 0.000
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.232 0.768 0.000
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.232 0.768 0.000
J95.5 Postprocedural subglottic stenosis
0.231 0.769 0.000
J62.0 Pneumoconiosis due to talc dust
0.230 0.769 0.000
J86.0 Pyothorax with fistula
0.230 0.769 0.000
E10.4 With neurological complications
0.230 0.770 0.000
J62.8 Pneumoconiosis due to other dust containing silica
0.228 0.771 0.000
I09.8 Other specified rheumatic heart diseases
0.227 0.772 0.000
I09.2 Chronic rheumatic pericarditis
0.227 0.772 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.227 0.772 0.000
I09.0 Rheumatic myocarditis
0.227 0.772 0.000
J95.8 Other postprocedural respiratory disorders
0.227 0.773 0.000
E10.3 With ophthalmic complications
0.226 0.774 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.219 0.780 0.001
J70.0 Acute pulmonary manifestations due to radiation
0.218 0.781 0.000
J70.9 Respiratory conditions due to unspecified external agent
0.218 0.782 0.000
J70.8 Respiratory conditions due to other specified external agents
0.218 0.782 0.000
J70.3 Chronic drug-induced interstitial lung disorders
0.218 0.782 0.000
J70.2 Acute drug-induced interstitial lung disorders
0.218 0.782 0.000
J95.0 Tracheostomy malfunction
0.217 0.783 0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.216 0.784 0.000
J70.4 Drug-induced interstitial lung disorder, unspecified
0.215 0.785 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.214 0.786 0.000
E10.5 With peripheral circulatory complications
0.212 0.788 0.000
J20-J22 Other acute lower respiratory infections
0.212 0.788 0.000
J95.4 Mendelson's syndrome
0.212 0.788 0.000
J95.3 Chronic pulmonary insufficiency following surgery
0.212 0.788 0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.212 0.788 0.000
I05 Rheumatic mitral valve diseases
0.211 0.789 0.000
J01 Acute sinusitis
0.210 0.790 0.000
E10.7 With multiple complications
0.209 0.791 0.000
I06.0 Rheumatic aortic stenosis
0.206 0.794 0.000
E10.2 With renal complications
0.204 0.796 0.000
J00 Acute nasopharyngitis [common cold]
0.204 0.796 0.000
J99.0 Rheumatoid lung disease
0.203 0.796 0.000
J96.9 Respiratory failure, unspecified
0.201 0.798 0.000
J96.1 Chronic respiratory failure
0.201 0.798 0.000
J96.0 Acute respiratory failure
0.201 0.798 0.000
J70.1 Chronic and other pulmonary manifestations due to radiation
0.200 0.799 0.000
J98.6 Disorders of diaphragm
0.199 0.801 0.000
E10.8 With unspecified complications
0.198 0.802 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.197 0.803 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.195 0.805 0.000
J93.0 Spontaneous tension pneumothorax
0.188 0.812 0.000
J98.8 Other specified respiratory disorders
0.185 0.814 0.000
J94.9 Pleural condition, unspecified
0.184 0.815 0.000
J45.8 Mixed asthma
0.183 0.817 0.000
J85.0 Gangrene and necrosis of lung
0.178 0.822 0.000
I07.9 Tricuspid valve disease, unspecified
0.177 0.823 0.000
I07.8 Other tricuspid valve diseases
0.177 0.823 0.000
I07.2 Tricuspid stenosis with insufficiency
0.177 0.823 0.000
I07.0 Tricuspid stenosis
0.177 0.823 0.000
J85.3 Abscess of mediastinum
0.176 0.824 0.000
J85.1 Abscess of lung with pneumonia
0.176 0.824 0.000
J02 Acute pharyngitis
0.176 0.824 0.000
J94.1 Fibrothorax
0.176 0.824 0.000
J45.1 Nonallergic asthma
0.175 0.825 0.000
J04 Acute laryngitis and tracheitis
0.174 0.826 0.000
I10-I15 Hypertensive diseases
0.174 0.826 0.000
I05.1 Rheumatic mitral insufficiency
0.172 0.828 0.000
J95.9 Postprocedural respiratory disorder, unspecified
0.171 0.829 0.000
J94.0 Chylous effusion
0.171 0.829 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.169 0.830 0.000
J93.8 Other pneumothorax
0.169 0.831 0.000
I27.2 Other secondary pulmonary hypertension
0.167 0.833 0.000
J01.4 Acute pansinusitis
0.165 0.834 0.000
J20 Acute bronchitis
0.164 0.836 0.000
J01.0 Acute maxillary sinusitis
0.163 0.837 0.000
J01.1 Acute frontal sinusitis
0.162 0.837 0.000
J01.8 Other acute sinusitis
0.162 0.838 0.000
J03 Acute tonsillitis
0.162 0.838 0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.157 0.842 0.001
J67.7 Air-conditioner and humidifier lung
0.157 0.842 0.001
J67.6 Maple-bark-stripper's lung
0.157 0.842 0.001
J67.5 Mushroom-worker's lung
0.157 0.842 0.001
J67.4 Maltworker's lung
0.157 0.842 0.001
J67.3 Suberosis
0.157 0.842 0.001
J67.1 Bagassosis
0.157 0.842 0.001
J67.0 Farmer's lung
0.157 0.842 0.001
J01.3 Acute sphenoidal sinusitis
0.150 0.849 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.149 0.850 0.001
J99.8 Respiratory disorders in other diseases classified elsewhere
0.145 0.855 0.000
J21 Acute bronchiolitis
0.145 0.855 0.000
J96.09 Acute respiratory failure; Type unspecified
0.144 0.855 0.000
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.144 0.855 0.000
J96.00 Acute respiratory failure; Type I [hypoxic]
0.144 0.855 0.000
J96.19 Chronic respiratory failure; Type unspecified
0.144 0.855 0.000
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.144 0.855 0.000
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.144 0.855 0.000
J96.99 Respiratory failure, unspecified; Type unspecified
0.144 0.855 0.000
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.144 0.855 0.000
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.144 0.855 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.144 0.856 0.000
J02.8 Acute pharyngitis due to other specified organisms
0.144 0.856 0.000
I05.0 Mitral stenosis
0.143 0.856 0.000
J05.1 Acute epiglottitis
0.143 0.857 0.000
I05.2 Mitral stenosis with insufficiency
0.142 0.857 0.000
J85.2 Abscess of lung without pneumonia
0.142 0.858 0.000
I05.8 Other mitral valve diseases
0.141 0.859 0.000
J05.0 Acute obstructive laryngitis [croup]
0.140 0.860 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.139 0.860 0.000
I07.1 Tricuspid insufficiency
0.139 0.860 0.000
J94.8 Other specified pleural conditions
0.139 0.861 0.000
J67.2 Bird fancier's lung
0.138 0.861 0.001
J01.2 Acute ethmoidal sinusitis
0.136 0.864 0.000
J02.0 Streptococcal pharyngitis
0.135 0.865 0.000
I15 Secondary hypertension
0.128 0.872 0.000
J20.9 Acute bronchitis, unspecified
0.127 0.873 0.000
J04.2 Acute laryngotracheitis
0.125 0.875 0.000
J01.9 Acute sinusitis, unspecified
0.123 0.877 0.000
I13 Hypertensive heart and renal disease
0.122 0.878 0.000
J20.8 Acute bronchitis due to other specified organisms
0.121 0.879 0.000
J93.9 Pneumothorax, unspecified
0.121 0.879 0.000
J04.0 Acute laryngitis
0.119 0.880 0.000
J20.7 Acute bronchitis due to echovirus
0.118 0.882 0.000
J20.6 Acute bronchitis due to rhinovirus
0.118 0.882 0.000
J20.5 Acute bronchitis due to respiratory syncytial virus
0.118 0.882 0.000
J20.4 Acute bronchitis due to parainfluenza virus
0.118 0.882 0.000
J20.3 Acute bronchitis due to coxsackie virus
0.118 0.882 0.000
J20.2 Acute bronchitis due to streptococcus
0.118 0.882 0.000
J20.1 Acute bronchitis due to Haemophilus influenzae
0.118 0.882 0.000
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.118 0.882 0.000
J03.8 Acute tonsillitis due to other specified organisms
0.116 0.883 0.000
J03.0 Streptococcal tonsillitis
0.116 0.883 0.000
J04.1 Acute tracheitis
0.115 0.885 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.111 0.889 0.000
E10.9 Without complications
0.110 0.890 0.000
J21.8 Acute bronchiolitis due to other specified organisms
0.104 0.896 0.000
J21.1 Acute bronchiolitis due to human metapneumovirus
0.104 0.896 0.000
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.104 0.896 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.104 0.896 0.000
I95 Hypotension
0.103 0.897 0.000
J09-J18 Influenza and pneumonia
0.102 0.898 0.000
I15.8 Other secondary hypertension
0.100 0.900 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.100 0.900 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.100 0.900 0.000
I98.0 Cardiovascular syphilis
0.100 0.900 0.000
J90 Pleural effusion, not elsewhere classified
0.098 0.902 0.000
I15.9 Seconday hypertension, unspecified
0.098 0.902 0.000
J21.9 Acute bronchiolitis, unspecified
0.097 0.903 0.000
J94.2 Haemothorax
0.096 0.903 0.001
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.096 0.904 0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.093 0.906 0.001
I15.2 Hypertension secondary to endocrine disorders
0.093 0.907 0.000
I15.1 Hypertension secondary to other renal disorders
0.092 0.908 0.000
J06.0 Acute laryngopharyngitis
0.092 0.908 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.091 0.909 0.000
I11 Hypertensive heart disease
0.089 0.911 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.088 0.912 0.000
I99 Other and unspecified disorders of circulatory system
0.088 0.912 0.000
J03.9 Acute tonsillitis, unspecified
0.088 0.912 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.087 0.912 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.087 0.913 0.000
I12 Hypertensive renal disease
0.087 0.913 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.087 0.913 0.000
I95.8 Other hypotension
0.087 0.913 0.000
I95.1 Orthostatic hypotension
0.085 0.915 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.084 0.915 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.084 0.916 0.000
J10 Influenza due to identified influenza virus
0.083 0.917 0.000
I05.9 Mitral valve disease, unspecified
0.079 0.921 0.000
J06.9 Acute upper respiratory infection, unspecified
0.077 0.923 0.000
I15.0 Renovascular hypertension
0.076 0.924 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.073 0.927 0.000
J09 Influenza due to certain identified influenza virus
0.073 0.927 0.000
E11.9 Without complications
0.072 0.928 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.071 0.929 0.000
J45.0 Predominantly allergic asthma
0.070 0.930 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.069 0.931 0.000
I97.0 Postcardiotomy syndrome
0.067 0.933 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.066 0.933 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.066 0.934 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.066 0.934 0.000
J17 Pneumonia in diseases classified elsewhere
0.065 0.935 0.000
J12 Viral pneumonia, not elsewhere classified
0.065 0.935 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.064 0.936 0.000
I95.0 Idiopathic hypotension
0.064 0.936 0.000
J14 Pneumonia due to Haemophilus influenzae
0.064 0.936 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.062 0.937 0.000
I97.1 Other functional disturbances following cardiac surgery
0.061 0.939 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.061 0.939 0.000
J10.8 Influenza with other manifestations, influenza virus identified
0.059 0.940 0.000
J02.9 Acute pharyngitis, unspecified
0.057 0.943 0.000
J15.2 Pneumonia due to staphylococcus
0.056 0.944 0.000
I12.9 Hypertensive renal disease without renal failure
0.056 0.944 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.054 0.946 0.000
J16.0 Chlamydial pneumonia
0.052 0.947 0.000
J16.8 Pneumonia due to other specified infectious organisms
0.052 0.948 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.052 0.948 0.000
I81 Portal vein thrombosis
0.051 0.949 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.051 0.949 0.000
I85 Oesophageal varices
0.050 0.950 0.000
J11 Influenza, virus not identified
0.050 0.950 0.000
J15.4 Pneumonia due to other streptococci
0.050 0.950 0.000
J15.5 Pneumonia due to Escherichia coli
0.050 0.950 0.000
J15.3 Pneumonia due to streptococcus, group B
0.049 0.950 0.000
J15.8 Other bacterial pneumonia
0.048 0.951 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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