TreeWAS – Variant ID: rs2992257

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.966	0.034
H53.8 Other visual disturbances	0.023	0.977	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.987	0.013
D32.0 Cerebral meninges	0.012	0.988	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.988	0.012
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.989	0.011
D86.0 Sarcoidosis of lung	0.009	0.990	0.000
D32.9 Meninges, unspecified	0.009	0.991	0.000
D86.8 Sarcoidosis of other and combined sites	0.009	0.991	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.000	0.991	0.009
D86 Sarcoidosis	0.009	0.991	0.000
D32 Benign neoplasm of meninges	0.009	0.991	0.000
I51.8 Other ill-defined heart diseases	0.008	0.992	0.000
D86.9 Sarcoidosis, unspecified	0.007	0.993	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.007	0.993	0.000
D47.2 Monoclonal gammopathy	0.007	0.993	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.000	0.993	0.007
D47.1 Chronic myeloproliferative disease	0.006	0.994	0.000
D86.3 Sarcoidosis of skin	0.006	0.994	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.006	0.994	0.000
D86.1 Sarcoidosis of lymph nodes	0.005	0.994	0.000
D32.1 Spinal meninges	0.005	0.995	0.000
D80-D89 Certain disorders involving the immune mechanism	0.005	0.995	0.000
S82.60 Fracture of lateral malleolus (closed)	0.005	0.995	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.005	0.995	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.005	0.995	0.000
D47.4 Osteomyelofibrosis	0.005	0.995	0.000
D80 Immunodeficiency with predominantly antibody defects	0.005	0.995	0.000
S61.7 Multiple open wounds of wrist and hand	0.005	0.995	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.995	0.004
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.004	0.995	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.004	0.995	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.004	0.995	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.996	0.004
D82 Immunodeficiency associated with other major defects	0.004	0.996	0.000
D81 Combined immunodeficiencies	0.004	0.996	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.004	0.996	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.004	0.996	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.996	0.004
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.000	0.996	0.004
D83 Common variable immunodeficiency	0.004	0.996	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.004	0.996	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.004	0.996	0.000
T45.5 Anticoagulants	0.004	0.996	0.000
D84 Other immunodeficiencies	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T42.4 Benzodiazepines	0.004	0.996	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.004	0.996	0.000
D25.1 Intramural leiomyoma of uterus	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.004	0.996	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.004	0.996	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.004	0.996	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.004	0.996	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.004	0.996	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.996	0.004
S61 Open wound of wrist and hand	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
D37.9 Digestive organ, unspecified	0.004	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.003	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.996	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
T40.4 Other synthetic narcotics	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.997	0.003
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
D81.9 Combined immunodeficiency, unspecified	0.003	0.997	0.000
D81.8 Other combined immunodeficiencies	0.003	0.997	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.997	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.997	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.997	0.000
D81.4 Nezelof's syndrome	0.003	0.997	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.997	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.997	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.997	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.997	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.997	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.997	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.997	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.997	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.997	0.000
D82.1 Di George's syndrome	0.003	0.997	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
G93.8 Other specified disorders of brain	0.003	0.997	0.000
S29.9 Unspecified injury of thorax	0.003	0.997	0.000
C22.0 Liver cell carcinoma	0.000	0.997	0.003
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.997	0.003
D83.8 Other common variable immunodeficiencies	0.003	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
D37.5 Rectum	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
T40.5 Cocaine	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
D37.1 Stomach	0.003	0.997	0.000
L89.2 Stage III decubitus ulcer	0.000	0.997	0.003
S61.8 Open wound of other parts of wrist and hand	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
S02.30 Fracture of orbital floor (closed)	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
D45 Polycythaemia vera	0.003	0.997	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.997	0.003
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.3 Methadone	0.003	0.997	0.000
T40.1 Heroin	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.003	0.997	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.997	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.003	0.997	0.000
Z93.3 Colostomy status	0.000	0.997	0.003
S61.1 Open wound of finger(s) with damage to nail	0.003	0.997	0.000
S82.6 Fracture of lateral malleolus	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.997	0.003
O35 Maternal care for known or suspected foetal abnormality and damage	0.003	0.997	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.003	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
T48.4 Expectorants	0.002	0.997	0.000
T48.3 Antitussives	0.002	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.997	0.000
T48.0 Oxytocic drugs	0.002	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.997	0.003
T40.2 Other opioids	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
T47.7 Emetics	0.002	0.997	0.000
T47.5 Digestants	0.002	0.997	0.000
T47.4 Other laxatives	0.002	0.997	0.000
T47.3 Saline and osmotic laxatives	0.002	0.997	0.000
T47.2 Stimulant laxatives	0.002	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.997	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.997	0.003
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
C77.9 Lymph node, unspecified	0.000	0.997	0.003
D48.7 Other specified sites	0.002	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.997	0.000
D37.3 Appendix	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
D48.5 Skin	0.002	0.998	0.000
X59.3 Sports and athletics area	0.002	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.002	0.998	0.000
Y83.9 Surgical procedure, unspecified	0.000	0.998	0.002
K56.7 Ileus, unspecified	0.000	0.998	0.002
S82.61 Fracture of lateral malleolus (open)	0.002	0.998	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.002	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.002	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.002	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.002	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.002	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.002	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
S29 Other and unspecified injuries of thorax	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
D48.4 Peritoneum	0.002	0.998	0.000
D48.3 Retroperitoneum	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
D48.6 Breast	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
D43.4 Spinal cord	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
Z33 Pregnant state, incidental	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.002	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S67 Crushing injury of wrist and hand	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
N71.1 Chronic inflammatory disease of uterus	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
L89 Decubitus ulcer	0.000	0.998	0.002
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.998	0.002
S60.0 Contusion of finger(s) without damage to nail	0.002	0.998	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.998	0.002
D37.7 Other digestive organs	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.002	0.998	0.000
S60-S69 Injuries to the wrist and hand	0.002	0.998	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.998	0.002
D39.0 Uterus	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.002	0.998	0.000
D42.1 Spinal meninges	0.002	0.998	0.000
D42.0 Cerebral meninges	0.002	0.998	0.000
C44.5 Skin of trunk	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.002	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.998	0.002
S63.0 Dislocation of wrist	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.998	0.002
D43.9 Central nervous system, unspecified	0.002	0.998	0.000
D43.7 Other parts of central nervous system	0.002	0.998	0.000
D43.3 Cranial nerves	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
X41.9 Unspecified place	0.002	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
M75.5 Bursitis of shoulder	0.002	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.002	0.998	0.000
T36.0 Penicillins	0.001	0.998	0.001
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
D43.0 Brain, supratentorial	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
I45.6 Preexcitation syndrome	0.002	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
D43.1 Brain, infratentorial	0.002	0.998	0.000
K29.2 Alcoholic gastritis	0.000	0.998	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.002	0.998	0.000
Z43.3 Attention to colostomy	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.998	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.002
S31.2 Open wound of penis	0.002	0.998	0.000
I51 Complications and ill-defined descriptions of heart disease	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
S65.1 Injury of radial artery at wrist and hand level	0.002	0.998	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.002	0.998	0.000
D41.4 Bladder	0.000	0.998	0.002
N42.1 Congestion and haemorrhage of prostate	0.000	0.998	0.002
S22.3 Fracture of rib	0.002	0.998	0.000
T79.5 Traumatic anuria	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.001	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.001	0.998	0.000
S65 Injury of blood vessels at wrist and hand level	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.001	0.998	0.000
S02.6 Fracture of mandible	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.998	0.000
X23.0 Home	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
E85.3 Secondary systemic amyloidosis	0.002	0.998	0.000
L40.8 Other psoriasis	0.002	0.998	0.000
S05.8 Other injuries of eye and orbit	0.002	0.998	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.001	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.001	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.001	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.000	0.998	0.001
D46 Myelodysplastic syndromes	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
N41.1 Chronic prostatitis	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.001
T79.9 Unspecified early complication of trauma	0.000	0.998	0.001
T79.4 Traumatic shock	0.000	0.998	0.001
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.998	0.001
T79.1 Fat embolism (traumatic)	0.000	0.998	0.001
T79.0 Air embolism (traumatic)	0.000	0.998	0.001
X12.0 Home	0.001	0.998	0.000
S97 Crushing injury of ankle and foot	0.001	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.001	0.998	0.000
E85.9 Amyloidosis, unspecified	0.002	0.998	0.000
S02.5 Fracture of tooth	0.001	0.998	0.000
T63.4 Venom of other arthropods	0.002	0.998	0.000
Z90.3 Acquired absence of part of stomach	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.001	0.998	0.000
D38.5 Other respiratory organs	0.001	0.998	0.000
D38.4 Thymus	0.001	0.998	0.000
D38.3 Mediastinum	0.001	0.998	0.000
D38.2 Pleura	0.001	0.998	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.001	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.998	0.001
D37.6 Liver, gallbladder and bile ducts	0.001	0.998	0.000
D38.0 Larynx	0.001	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.001	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.001	0.998	0.000
M84.08 Malunion of fracture (Other)	0.001	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.001	0.998	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.001	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.001	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.998	0.000
L40 Psoriasis	0.001	0.998	0.000
S68 Traumatic amputation of wrist and hand	0.001	0.998	0.000
S60 Superficial injury of wrist and hand	0.001	0.998	0.000
D44.8 Pluriglandular involvement	0.001	0.999	0.000
H59.0 Vitreous syndrome following cataract surgery	0.000	0.999	0.001
I51.2 Rupture of papillary muscle, not elsewhere classified	0.001	0.999	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.999	0.001
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.001	0.999	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.999	0.000
S22.1 Multiple fractures of thoracic spine	0.001	0.999	0.000
S31 Open wound of abdomen, lower back and pelvis	0.001	0.999	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.001	0.999	0.000
S63.1 Dislocation finger	0.001	0.999	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.001	0.999	0.000
S63.2 Multiple dislocations of fingers	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.001	0.999	0.000
T79.8 Other early complications of trauma	0.000	0.999	0.001
M84.02 Malunion of fracture (Upper arm)	0.001	0.999	0.000
S22.31 Fracture of rib (open)	0.001	0.999	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.001	0.999	0.000
D40.9 Male genital organ, unspecified	0.001	0.999	0.000
D40.7 Other male genital organs	0.001	0.999	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.999	0.001
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.999	0.001
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.001	0.999	0.001
M84.04 Malunion of fracture (Hand)	0.001	0.999	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.000	0.999	0.001
D44.9 Endocrine gland, unspecified	0.001	0.999	0.000
D44.6 Carotid body	0.001	0.999	0.000
D44.5 Pineal gland	0.001	0.999	0.000
D44.2 Parathyroid gland	0.001	0.999	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.999	0.001
L89.1 Stage II decubitus ulcer	0.000	0.999	0.001
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.001	0.999	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.001	0.999	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.001	0.999	0.000
S65.4 Injury of blood vessel(s) of thumb	0.001	0.999	0.000
S65.3 Injury of deep palmar arch	0.001	0.999	0.000
S65.2 Injury of superficial palmar arch	0.001	0.999	0.000
S91.3 Open wound of other parts of foot	0.001	0.999	0.000
S91.0 Open wound of ankle	0.001	0.999	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.001	0.999	0.000
S02.61 Fracture of mandible (open)	0.001	0.999	0.000
D44.7 Aortic body and other paraganglia	0.001	0.999	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.001	0.999	0.000
C26.0 Intestinal tract, part unspecified	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.001	0.999	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.001	0.999	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.001	0.999	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.001	0.999	0.000
D46.1 Refractory anaemia with sideroblasts	0.001	0.999	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.001	0.999	0.000
K56.2 Volvulus	0.001	0.999	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.999	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.001	0.999	0.000
S97.1 Crushing injury of toe(s)	0.001	0.999	0.000
S97.0 Crushing injury of ankle	0.001	0.999	0.000
S69 Other and unspecified injuries of wrist and hand	0.001	0.999	0.000
S02.51 Fracture of tooth (open)	0.001	0.999	0.000
B37.8 Candidiasis of other sites	0.000	0.999	0.001
D46.2 Refractory anaemia with excess of blasts	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations