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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3093664
log Bayes Factor = 56.034
Chromosome 6   position 31,544,642  (GRCh37) Explore rs3093664 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
J47 Bronchiectasis
0.000 0.002 0.998
J30-J39 Other diseases of upper respiratory tract
0.000 0.003 0.997
Chapter X Diseases of the respiratory system
0.000 0.005 0.995
J44 Other chronic obstructive pulmonary disease
0.000 0.008 0.992
J33.0 Polyp of nasal cavity
0.000 0.012 0.988
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.016 0.984
L40.0 Psoriasis vulgaris
0.976 0.024 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.030 0.970
E10 Insulin-dependent diabetes mellitus
0.000 0.030 0.970
E10-E14 Diabetes mellitus
0.000 0.033 0.967
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.037 0.963
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.042 0.958
E10.3 With ophthalmic complications
0.000 0.058 0.942
E10.9 Without complications
0.000 0.061 0.939
E07 Other disorders of thyroid
0.000 0.098 0.902
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.101 0.899
J33.8 Other polyp of sinus
0.000 0.112 0.888
J32 Chronic sinusitis
0.000 0.112 0.888
E10.4 With neurological complications
0.000 0.119 0.881
L40.1 Generalised pustular psoriasis
0.864 0.136 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.150 0.850
E10.1 With ketoacidosis
0.000 0.154 0.846
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.165 0.835
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.165 0.835
J31.0 Chronic rhinitis
0.000 0.179 0.821
J39 Other diseases of upper respiratory tract
0.000 0.182 0.818
L40.8 Other psoriasis
0.816 0.184 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.192 0.808
E06 Thyroiditis
0.000 0.194 0.806
J32.0 Chronic maxillary sinusitis
0.000 0.211 0.789
J00-J06 Acute upper respiratory infections
0.000 0.221 0.779
E10.5 With peripheral circulatory complications
0.000 0.224 0.776
E50-E64 Other nutritional deficiencies
0.000 0.228 0.771
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.228 0.771
E16 Other disorders of pancreatic internal secretion
0.000 0.263 0.737
E03.8 Other specified hypothyroidism
0.000 0.266 0.734
J32.4 Chronic pansinusitis
0.000 0.281 0.719
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
J32.2 Chronic ethmoidal sinusitis
0.000 0.290 0.709
J36 Peritonsillar abscess
0.000 0.292 0.708
J60-J70 Lung diseases due to external agents
0.000 0.292 0.708
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.296 0.704
J39.2 Other diseases of pharynx
0.000 0.296 0.704
E10.7 With multiple complications
0.000 0.304 0.695
E10.6 With other specified complications
0.000 0.304 0.695
E10.2 With renal complications
0.000 0.304 0.695
E10.0 With coma
0.000 0.304 0.695
E12 Malnutrition-related diabetes mellitus
0.000 0.307 0.693
E10.8 With unspecified complications
0.000 0.312 0.688
E14 Unspecified diabetes mellitus
0.000 0.320 0.680
J34 Other disorders of nose and nasal sinuses
0.000 0.320 0.680
J03 Acute tonsillitis
0.000 0.323 0.677
J31.2 Chronic pharyngitis
0.000 0.327 0.672
E55 Vitamin D deficiency
0.000 0.328 0.672
E16.2 Hypoglycaemia, unspecified
0.000 0.332 0.668
C18.7 Sigmoid colon
0.667 0.333 0.000
K90 Intestinal malabsorption
0.000 0.334 0.666
J46 Status asthmaticus
0.000 0.346 0.654
J37 Chronic laryngitis and laryngotracheitis
0.000 0.347 0.653
J35 Chronic diseases of tonsils and adenoids
0.000 0.348 0.652
J84 Other interstitial pulmonary diseases
0.000 0.350 0.650
E07.1 Dyshormogenetic goitre
0.000 0.353 0.647
E07.0 Hypersecretion of calcitonin
0.000 0.353 0.647
J31.1 Chronic nasopharyngitis
0.000 0.355 0.645
J32.3 Chronic sphenoidal sinusitis
0.000 0.363 0.637
J86 Pyothorax
0.000 0.367 0.633
E06.9 Thyroiditis, unspecified
0.000 0.370 0.630
J45.0 Predominantly allergic asthma
0.000 0.374 0.626
E06.3 Autoimmune thyroiditis
0.000 0.374 0.625
J80 Adult respiratory distress syndrome
0.000 0.378 0.622
J32.8 Other chronic sinusitis
0.000 0.378 0.622
J01 Acute sinusitis
0.000 0.382 0.618
J03.9 Acute tonsillitis, unspecified
0.000 0.396 0.604
J00 Acute nasopharyngitis [common cold]
0.000 0.396 0.604
K90.9 Intestinal malabsorption, unspecified
0.000 0.399 0.601
E55.9 Vitamin D deficiency, unspecified
0.000 0.400 0.600
E15 Nondiabetic hypoglycaemic coma
0.000 0.402 0.598
J32.1 Chronic frontal sinusitis
0.000 0.402 0.597
J30 Vasomotor and allergic rhinitis
0.000 0.404 0.596
E20-E35 Disorders of other endocrine glands
0.000 0.407 0.593
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.411 0.589
J39.9 Disease of upper respiratory tract, unspecified
0.000 0.413 0.587
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.000 0.413 0.587
J39.1 Other abscess of pharynx
0.000 0.413 0.587
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.413 0.587
E70-E90 Metabolic disorders
0.000 0.417 0.583
E65-E68 Obesity and other hyperalimentation
0.000 0.417 0.583
E53 Deficiency of other B group vitamins
0.000 0.420 0.580
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.420 0.580
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.421 0.579
E06.5 Other chronic thyroiditis
0.000 0.422 0.578
E06.4 Drug-induced thyroiditis
0.000 0.422 0.578
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.422 0.578
E06.1 Subacute thyroiditis
0.000 0.422 0.578
E06.0 Acute thyroiditis
0.000 0.422 0.578
E14.3 With ophthalmic complications
0.000 0.431 0.569
J81 Pulmonary oedema
0.000 0.431 0.569
J34.0 Abscess, furuncle and carbuncle of nose
0.000 0.433 0.567
J35.1 Hypertrophy of tonsils
0.000 0.434 0.566
E07.8 Other specified disorders of thyroid
0.000 0.440 0.559
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.441 0.559
J39.8 Other specified diseases of upper respiratory tract
0.000 0.441 0.559
J42 Unspecified chronic bronchitis
0.000 0.442 0.558
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.447 0.553
E63 Other nutritional deficiencies
0.000 0.447 0.553
E56 Other vitamin deficiencies
0.000 0.447 0.553
E51 Thiamine deficiency
0.000 0.447 0.553
E50 Vitamin A deficiency
0.000 0.447 0.553
E60 Dietary zinc deficiency
0.000 0.447 0.553
E59 Dietary selenium deficiency
0.000 0.447 0.553
E58 Dietary calcium deficiency
0.000 0.447 0.553
E54 Ascorbic acid deficiency
0.000 0.447 0.553
E52 Niacin deficiency [pellagra]
0.000 0.447 0.553
J32.9 Chronic sinusitis, unspecified
0.000 0.452 0.548
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.457 0.543
E40-E46 Malnutrition
0.000 0.458 0.542
E89.0 Postprocedural hypothyroidism
0.000 0.461 0.539
J34.2 Deviated nasal septum
0.000 0.462 0.538
J01.9 Acute sinusitis, unspecified
0.000 0.465 0.535
J86.9 Pyothorax without fistula
0.000 0.467 0.533
E13 Other specified diabetes mellitus
0.001 0.471 0.529
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.471 0.529
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.471 0.529
E16.4 Abnormal secretion of gastrin
0.000 0.471 0.529
E16.3 Increased secretion of glucagon
0.000 0.471 0.529
E16.1 Other hypoglycaemia
0.000 0.471 0.529
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.471 0.529
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.478 0.522
J85 Abscess of lung and mediastinum
0.000 0.480 0.520
J34.1 Cyst and mucocele of nose and nasal sinus
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
J70 Respiratory conditions due to other external agents
0.000 0.492 0.508
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.492 0.508
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.492 0.508
J66 Airway disease due to specific organic dust
0.000 0.492 0.508
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.492 0.508
J62 Pneumoconiosis due to dust containing silica
0.000 0.492 0.508
J65 Pneumoconiosis associated with tuberculosis
0.000 0.492 0.508
J64 Unspecified pneumoconiosis
0.000 0.492 0.508
J60 Coalworker's pneumoconiosis
0.000 0.492 0.508
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.494 0.505
J95-J99 Other diseases of the respiratory system
0.000 0.498 0.501
J30.4 Allergic rhinitis, unspecified
0.000 0.500 0.500
J04 Acute laryngitis and tracheitis
0.000 0.502 0.498
E12.9 Without complications
0.000 0.503 0.497
E12.8 With unspecified complications
0.000 0.503 0.497
E12.7 With multiple complications
0.000 0.503 0.497
E12.6 With other specified complications
0.000 0.503 0.497
E12.5 With peripheral circulatory complications
0.000 0.503 0.497
E12.4 With neurological complications
0.000 0.503 0.497
E12.3 With ophthalmic complications
0.000 0.503 0.497
E12.2 With renal complications
0.000 0.503 0.497
E12.1 With ketoacidosis
0.000 0.503 0.497
E12.0 With coma
0.000 0.503 0.497
E27 Other disorders of adrenal gland
0.000 0.504 0.496
J34.3 Hypertrophy of nasal turbinates
0.000 0.509 0.491
E83 Disorders of mineral metabolism
0.000 0.512 0.488
E14.8 With unspecified complications
0.000 0.512 0.488
E14.7 With multiple complications
0.000 0.512 0.488
E14.6 With other specified complications
0.000 0.512 0.488
E14.5 With peripheral circulatory complications
0.000 0.512 0.488
E14.4 With neurological complications
0.000 0.512 0.488
E14.2 Withrenal complications
0.000 0.512 0.488
E14.1 With ketoacidosis
0.000 0.512 0.488
E14.0 With coma
0.000 0.512 0.488
E65 Localised adiposity
0.000 0.512 0.488
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.514 0.485
J03.0 Streptococcal tonsillitis
0.000 0.514 0.485
J35.0 Chronic tonsillitis
0.000 0.515 0.485
E55.0 Rickets, active
0.000 0.518 0.482
K90.8 Other intestinal malabsorption
0.000 0.522 0.478
K90.3 Pancreatic steatorrhoea
0.000 0.522 0.478
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.522 0.478
K90.1 Tropical sprue
0.000 0.522 0.478
J37.1 Chronic laryngotracheitis
0.000 0.532 0.468
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.000 0.532 0.467
J35.2 Hypertrophy of adenoids
0.000 0.532 0.467
J84.8 Other specified interstitial pulmonary diseases
0.000 0.534 0.466
J84.0 Alveolar and parietoalveolar conditions
0.000 0.534 0.466
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.535 0.465
E29 Testicular dysfunction
0.000 0.539 0.461
E27.1 Primary adrenocortical insufficiency
0.000 0.541 0.459
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.545 0.455
J86.0 Pyothorax with fistula
0.000 0.546 0.454
E73 Lactose intolerance
0.000 0.547 0.453
E83.4 Disorders of magnesium metabolism
0.000 0.553 0.447
J20-J22 Other acute lower respiratory infections
0.000 0.553 0.447
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.553 0.446
E89.2 Postprocedural hypoparathyroidism
0.000 0.556 0.444
E53.8 Deficiency of other specified B group vitamins
0.000 0.557 0.443
J01.8 Other acute sinusitis
0.000 0.557 0.443
J01.4 Acute pansinusitis
0.000 0.557 0.443
J01.3 Acute sphenoidal sinusitis
0.000 0.557 0.443
J01.2 Acute ethmoidal sinusitis
0.000 0.557 0.443
J01.1 Acute frontal sinusitis
0.000 0.557 0.443
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.000 0.557 0.442
E04 Other non-toxic goitre
0.000 0.559 0.441
E85 Amyloidosis
0.000 0.562 0.438
E20 Hypoparathyroidism
0.000 0.570 0.430
E89.3 Postprocedural hypopituitarism
0.000 0.572 0.428
J30.2 Other seasonal allergic rhinitis
0.000 0.572 0.427
J30.0 Vasomotor rhinitis
0.000 0.572 0.427
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.575 0.425
E32 Diseases of thymus
0.000 0.575 0.425
E31 Polyglandular dysfunction
0.000 0.575 0.425
E30 Disorders of puberty, not elsewhere classified
0.000 0.575 0.425
E25 Adrenogenital disorders
0.000 0.575 0.425
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.577 0.423
J02 Acute pharyngitis
0.000 0.581 0.418
E84 Cystic fibrosis
0.000 0.582 0.418
E79 Disorders of purine and pyrimidine metabolism
0.000 0.582 0.418
E77 Disorders of glycoprotein metabolism
0.000 0.582 0.418
E76 Disorders of glycosaminoglycan metabolism
0.000 0.582 0.418
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.582 0.418
E72 Other disorders of amino-acid metabolism
0.000 0.582 0.418
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.582 0.418
E70 Disorders of aromatic amino-acid metabolism
0.000 0.582 0.418
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.582 0.418
E67 Other hyperalimentation
0.000 0.582 0.418
E68 Sequelae of hyperalimentation
0.000 0.582 0.418
E53.9 Vitamin B deficiency, unspecified
0.000 0.584 0.416
E53.1 Pyridoxine deficiency
0.000 0.584 0.416
E53.0 Riboflavin deficiency
0.000 0.584 0.416
E61 Deficiency of other nutrient elements
0.001 0.584 0.415
E34 Other endocrine disorders
0.000 0.588 0.412
E74 Other disorders of carbohydrate metabolism
0.000 0.589 0.411
E26 Hyperaldosteronism
0.000 0.594 0.406
J37.0 Chronic laryngitis
0.000 0.594 0.406
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.599 0.401
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.599 0.401
E89.5 Postprocedural testicular hypofunction
0.000 0.599 0.401
E89.4 Postprocedural ovarian failure
0.000 0.599 0.401
E89.1 Postprocedural hypoinsulinaemia
0.000 0.599 0.401
E50.9 Vitamin A deficiency, unspecified
0.000 0.603 0.397
E50.8 Other manifestations of vitamin A deficiency
0.000 0.603 0.397
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.603 0.397
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.603 0.397
E50.5 Vitamin A deficiency with night blindness
0.000 0.603 0.397
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.603 0.397
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.603 0.397
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.603 0.397
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.603 0.397
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.603 0.397
E51.9 Thiamine deficiency, unspecified
0.000 0.603 0.397
E51.8 Other manifestations of thiamine deficiency
0.000 0.603 0.397
E51.2 Wernicke's encephalopathy
0.000 0.603 0.397
E51.1 Beriberi
0.000 0.603 0.397
E56.9 Vitamin deficiency, unspecified
0.000 0.603 0.397
E56.8 Deficiency of other vitamins
0.000 0.603 0.397
E56.1 Deficiency of vitamin K
0.000 0.603 0.397
E56.0 Deficiency of vitamin E
0.000 0.603 0.397
E63.9 Nutritional deficiency, unspecified
0.000 0.603 0.397
E63.8 Other specified nutritional deficiencies
0.000 0.603 0.397
E63.1 Imbalance of constituents of food intake
0.000 0.603 0.397
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.603 0.397
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.603 0.397
E64.8 Sequelae of other nutritional deficiencies
0.000 0.603 0.397
E64.3 Sequelae of rickets
0.000 0.603 0.397
E64.2 Sequelae of vitamin C deficiency
0.000 0.603 0.397
E64.1 Sequelae of vitamin A deficiency
0.000 0.603 0.397
E64.0 Sequelae of protein-energy malnutrition
0.000 0.603 0.397
E23 Hypofunction and other disorders of pituitary gland
0.000 0.609 0.391
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.611 0.389
J06.0 Acute laryngopharyngitis
0.000 0.611 0.389
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.611 0.389
E45 Retarded development following protein-energy malnutrition
0.000 0.611 0.389
E43 Unspecified severe protein-energy malnutrition
0.000 0.611 0.389
E42 Marasmic kwashiorkor
0.000 0.611 0.389
E41 Nutritional marasmus
0.000 0.611 0.389
E40 Kwashiorkor
0.000 0.611 0.389
J69 Pneumonitis due to solids and liquids
0.000 0.613 0.386
J43 Emphysema
0.001 0.619 0.380
E13.8 With unspecified complications
0.001 0.620 0.379
E13.7 With multiple complications
0.001 0.620 0.379
E13.6 With other specified complications
0.001 0.620 0.379
E13.5 With peripheral circulatory complications
0.001 0.620 0.379
E13.4 With neurological complications
0.001 0.620 0.379
E13.3 With ophthalmic complications
0.001 0.620 0.379
E13.2 With renal complications
0.001 0.620 0.379
E13.1 With ketoacidosis
0.001 0.620 0.379
E13.0 With coma
0.001 0.620 0.379
E21.3 Hyperparathyroidism, unspecified
0.000 0.622 0.378
J05.0 Acute obstructive laryngitis [croup]
0.000 0.625 0.374
J01.0 Acute maxillary sinusitis
0.000 0.626 0.374
M35.3 Polymyalgia rheumatica
0.000 0.626 0.374
J06.9 Acute upper respiratory infection, unspecified
0.000 0.627 0.373
J85.3 Abscess of mediastinum
0.000 0.627 0.373
J85.2 Abscess of lung without pneumonia
0.000 0.627 0.373
J85.0 Gangrene and necrosis of lung
0.000 0.627 0.373
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.631 0.369
M35.0 Sicca syndrome [Sjogren]
0.000 0.632 0.368
E29.1 Testicular hypofunction
0.000 0.633 0.366
J40 Bronchitis, not specified as acute or chronic
0.000 0.634 0.366
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.636 0.364
J62.0 Pneumoconiosis due to talc dust
0.000 0.636 0.364
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.636 0.364
J63.5 Stannosis
0.000 0.636 0.364
J63.4 Siderosis
0.000 0.636 0.364
J63.3 Graphite fibrosis (of lung)
0.000 0.636 0.364
J63.2 Berylliosis
0.000 0.636 0.364
J63.1 Bauxite fibrosis (of lung)
0.000 0.636 0.364
J63.0 Aluminosis (of lung)
0.000 0.636 0.364
J66.8 Airway disease due to other specific organic dusts
0.000 0.636 0.364
J66.2 Cannabinosis
0.000 0.636 0.364
J66.1 Flax-dresser's disease
0.000 0.636 0.364
J66.0 Byssinosis
0.000 0.636 0.364
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.636 0.364
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.636 0.364
J67.7 Air-conditioner and humidifier lung
0.000 0.636 0.364
J67.6 Maple-bark-stripper's lung
0.000 0.636 0.364
J67.5 Mushroom-worker's lung
0.000 0.636 0.364
J67.4 Maltworker's lung
0.000 0.636 0.364
J67.3 Suberosis
0.000 0.636 0.364
J67.2 Bird fancier's lung
0.000 0.636 0.364
J67.1 Bagassosis
0.000 0.636 0.364
J67.0 Farmer's lung
0.000 0.636 0.364
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.636 0.364
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.636 0.364
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.636 0.364
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.636 0.364
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.636 0.364
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.636 0.364
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.636 0.364
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.636 0.364
J70.8 Respiratory conditions due to other specified external agents
0.000 0.636 0.364
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.636 0.364
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.636 0.364
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.636 0.364
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.636 0.364
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.636 0.364
J30.3 Other allergic rhinitis
0.000 0.637 0.363
M35 Other systemic involvement of connective tissue
0.000 0.639 0.361
J90-J94 Other diseases of pleura
0.000 0.640 0.360
J96 Respiratory failure, not elsewhere classified
0.000 0.640 0.360
E73.9 Lactose intolerance, unspecified
0.000 0.641 0.359
J04.2 Acute laryngotracheitis
0.000 0.643 0.357
E27.5 Adrenomedullary hyperfunction
0.000 0.644 0.355
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.644 0.355
E27.0 Other adrenocortical overactivity
0.000 0.644 0.355
E28 Ovarian dysfunction
0.000 0.645 0.355
E83.1 Disorders of iron metabolism
0.000 0.646 0.354
E22 Hyperfunction of pituitary gland
0.000 0.647 0.352
E88 Other metabolic disorders
0.000 0.649 0.351
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.650 0.350
E83.8 Other disorders of mineral metabolism
0.000 0.650 0.350
E83.2 Disorders of zinc metabolism
0.000 0.650 0.350
E83.0 Disorders of copper metabolism
0.000 0.650 0.350
E80.4 Gilbert's syndrome
0.000 0.652 0.348
E21.0 Primary hyperparathyroidism
0.000 0.658 0.342
E27.8 Other specified disorders of adrenal gland
0.000 0.660 0.340
J85.1 Abscess of lung with pneumonia
0.000 0.660 0.339
J05.1 Acute epiglottitis
0.000 0.662 0.338
E85.9 Amyloidosis, unspecified
0.000 0.663 0.337
E27.2 Addisonian crisis
0.000 0.666 0.334
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.667 0.333
E21.4 Other specified disorders of parathyroid gland
0.000 0.667 0.333
E21.2 Other hyperparathyroidism
0.000 0.667 0.333
J04.1 Acute tracheitis
0.000 0.668 0.331
E29.9 Testicular dysfunction, unspecified
0.000 0.669 0.331
E29.8 Other testicular dysfunction
0.000 0.669 0.331
E29.0 Testicular hyperfunction
0.000 0.669 0.331
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.670 0.330
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.670 0.330
E83.3 Disorders of phosphorus metabolism
0.000 0.670 0.330
J04.0 Acute laryngitis
0.000 0.673 0.327
E14.9 Without complications
0.000 0.675 0.325
E73.8 Other lactose intolerance
0.000 0.675 0.325
E73.1 Secondary lactase deficiency
0.000 0.675 0.325
E73.0 Congenital lactase deficiency
0.000 0.675 0.325
E24 Cushing's syndrome
0.000 0.676 0.323
J21 Acute bronchiolitis
0.000 0.679 0.320
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.680 0.320
E80.6 Other disorders of bilirubin metabolism
0.000 0.680 0.320
E80.5 Crigler-Najjar syndrome
0.000 0.680 0.320
E80.3 Defects of catalase and peroxydase
0.000 0.680 0.320
E80.2 Other porphyria
0.000 0.680 0.320
E80.1 Porphyria cutanea tarda
0.000 0.680 0.320
E80.0 Hereditary erythropoietic porphyria
0.000 0.680 0.320
E27.9 Disorder of adrenal gland, unspecified
0.000 0.682 0.318
E04.8 Other specified non-toxic goitre
0.000 0.684 0.316
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.685 0.315
L40-L45 Papulosquamous disorders
0.315 0.685 0.000
E85.8 Other amyloidosis
0.000 0.685 0.314
E85.3 Secondary systemic amyloidosis
0.000 0.685 0.314
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.685 0.314
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.685 0.314
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.685 0.314
E04.9 Non-toxic goitre, unspecified
0.000 0.687 0.313
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.687 0.313
E20.9 Hypoparathyroidism, unspecified
0.000 0.687 0.312
E85.4 Organ-limited amyloidosis
0.000 0.689 0.311
E20.8 Other hypoparathyroidism
0.000 0.692 0.308
E20.1 Pseudohypoparathyroidism
0.000 0.692 0.308
E20.0 Idiopathic hypoparathyroidism
0.000 0.692 0.308
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.693 0.306
E34.9 Endocrine disorder, unspecified
0.000 0.695 0.305
E25.9 Adrenogenital disorder, unspecified
0.000 0.695 0.305
E25.8 Other adrenogenital disorders
0.000 0.695 0.305
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.695 0.305
E30.9 Disorder of puberty, unspecified
0.000 0.695 0.305
E30.8 Other disorders of puberty
0.000 0.695 0.305
E30.1 Precocious puberty
0.000 0.695 0.305
E30.0 Delayed puberty
0.000 0.695 0.305
E31.9 Polyglandular dysfunction, unspecified
0.000 0.695 0.305
E31.8 Other polyglandular dysfunction
0.000 0.695 0.305
E31.1 Polyglandular hyperfunction
0.000 0.695 0.305
E31.0 Autoimmune polyglandular failure
0.000 0.695 0.305
E32.9 Disease of thymus, unspecified
0.000 0.695 0.305
E32.8 Other diseases of thymus
0.000 0.695 0.305
E32.1 Abscess of thymus
0.000 0.695 0.305
E32.0 Persistent hyperplasia of thymus
0.000 0.695 0.305
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.695 0.305
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.695 0.305
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.695 0.305
J99.0 Rheumatoid lung disease
0.000 0.696 0.303
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.700 0.300
J02.0 Streptococcal pharyngitis
0.000 0.700 0.300
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.700 0.300
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.700 0.300
E70.3 Albinism
0.000 0.700 0.300
E70.2 Disorders of tyrosine metabolism
0.000 0.700 0.300
E70.1 Other hyperphenylalaninaemias
0.000 0.700 0.300
E70.0 Classical phenylketonuria
0.000 0.700 0.300
E71.3 Disorders of fatty-acid metabolism
0.000 0.700 0.300
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.700 0.300
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.700 0.300
E71.0 Maple-syrup-urine disease
0.000 0.700 0.300
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.700 0.300
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.700 0.300
E72.5 Disorders of glycine metabolism
0.000 0.700 0.300
E72.4 Disorders of ornithine metabolism
0.000 0.700 0.300
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.700 0.300
E72.2 Disorders of urea cycle metabolism
0.000 0.700 0.300
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.700 0.300
E72.0 Disorders of amino-acid transport
0.000 0.700 0.300
E75.6 Lipid storage disorder, unspecified
0.000 0.700 0.300
E75.5 Other lipid storage disorders
0.000 0.700 0.300
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.700 0.300
E75.3 Sphingolipidosis, unspecified
0.000 0.700 0.300
E75.2 Other sphingolipidosis
0.000 0.700 0.300
E75.1 Other gangliosidosis
0.000 0.700 0.300
E75.0 GM2 gangliosidosis
0.000 0.700 0.300
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.700 0.300
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.700 0.300
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.700 0.300
E76.2 Other mucopolysaccharidoses
0.000 0.700 0.300
E76.1 Mucopolysaccharidosis, type II
0.000 0.700 0.300
E76.0 Mucopolysaccharidosis, type I
0.000 0.700 0.300
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.700 0.300
E77.8 Other disorders of glycoprotein metabolism
0.000 0.700 0.300
E77.1 Defects in glycoprotein degradation
0.000 0.700 0.300
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.700 0.300
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.700 0.300
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.700 0.300
E79.1 Lesch-Nyhan syndrome
0.000 0.700 0.300
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.700 0.300
E84.9 Cystic fibrosis, unspecified
0.000 0.700 0.300

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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