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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3093983
log Bayes Factor = 64.4472
Chromosome 6   position 31,496,925  (GRCh37) Explore rs3093983 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
E78.0 Pure hypercholesterolaemia
0.000 0.002 0.998
I20 Angina pectoris
0.000 0.005 0.995
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.006 0.994
E14.3 With ophthalmic complications
0.000 0.009 0.991
I25.5 Ischaemic cardiomyopathy
0.000 0.010 0.990
E14.9 Without complications
0.000 0.011 0.989
E10.1 With ketoacidosis
0.000 0.013 0.987
I20.9 Angina pectoris, unspecified
0.000 0.014 0.986
I22 Subsequent myocardial infarction
0.000 0.016 0.984
E10.4 With neurological complications
0.000 0.017 0.983
I20.0 Unstable angina
0.000 0.028 0.972
I25.2 Old myocardial infarction
0.000 0.037 0.963
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.037 0.963
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.040 0.960
I21 Acute myocardial infarction
0.000 0.041 0.959
G35-G37 Demyelinating diseases of the central nervous system
0.957 0.043 0.000
G37 Other demyelinating diseases of central nervous system
0.949 0.051 0.000
E13 Other specified diabetes mellitus
0.000 0.064 0.936
I10 Essential (primary) hypertension
0.000 0.065 0.935
I21.9 Acute myocardial infarction, unspecified
0.000 0.071 0.929
G37.9 Demyelinating disease of central nervous system, unspecified
0.927 0.073 0.000
E83.1 Disorders of iron metabolism
0.919 0.081 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.089 0.911
I24 Other acute ischaemic heart diseases
0.000 0.093 0.907
E70-E90 Metabolic disorders
0.000 0.096 0.904
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.106 0.894
E13.9 Without complications
0.000 0.110 0.890
E10.2 With renal complications
0.000 0.118 0.882
E78.8 Other disorders of lipoprotein metabolism
0.000 0.121 0.879
L40-L45 Papulosquamous disorders
0.000 0.123 0.877
E11.2 With renal complications
0.000 0.125 0.875
E11.0 With coma
0.000 0.135 0.865
R07.4 Chest pain, unspecified
0.000 0.142 0.858
I10-I15 Hypertensive diseases
0.000 0.145 0.855
L43 Lichen planus
0.000 0.151 0.849
I25.3 Aneurysm of heart
0.000 0.154 0.846
L40.8 Other psoriasis
0.000 0.159 0.841
I21.4 Acute subendocardial myocardial infarction
0.000 0.161 0.839
E11.1 With ketoacidosis
0.000 0.165 0.835
G37.8 Other specified demyelinating diseases of central nervous system
0.833 0.167 0.000
E14.4 With neurological complications
0.000 0.176 0.824
E10.8 With unspecified complications
0.000 0.180 0.820
L43.9 Lichen planus, unspecified
0.000 0.184 0.816
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.185 0.814
E00-E07 Disorders of thyroid gland
0.000 0.195 0.805
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.201 0.799
E10.5 With peripheral circulatory complications
0.000 0.202 0.798
L40.0 Psoriasis vulgaris
0.000 0.206 0.794
E10.0 With coma
0.000 0.206 0.794
I23 Certain current complications following acute myocardial infarction
0.000 0.212 0.788
I24.8 Other forms of acute ischaemic heart disease
0.000 0.216 0.784
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.218 0.782
E78.2 Mixed hyperlipidaemia
0.000 0.218 0.782
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.220 0.780
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.773 0.227 0.000
E11.6 With other specified complications
0.000 0.231 0.769
E03 Other hypothyroidism
0.000 0.239 0.761
I15 Secondary hypertension
0.000 0.248 0.752
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.248 0.752
E03.9 Hypothyroidism, unspecified
0.000 0.253 0.747
E85 Amyloidosis
0.000 0.255 0.745
E10.6 With other specified complications
0.000 0.266 0.734
E14.5 With peripheral circulatory complications
0.000 0.266 0.734
I12 Hypertensive renal disease
0.000 0.267 0.733
E78.6 Lipoprotein deficiency
0.000 0.269 0.731
E05.9 Thyrotoxicosis, unspecified
0.000 0.278 0.722
E14.6 With other specified complications
0.000 0.278 0.722
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E74 Other disorders of carbohydrate metabolism
0.000 0.295 0.705
E78.1 Pure hyperglyceridaemia
0.000 0.298 0.702
L43.8 Other lichen planus
0.000 0.299 0.701
L40.3 Pustulosis palmaris et plantaris
0.000 0.305 0.694
E78.3 Hyperchylomicronaemia
0.000 0.310 0.690
G36 Other acute disseminated demyelination
0.690 0.310 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.312 0.687
E11.5 With peripheral circulatory complications
0.000 0.313 0.687
E16 Other disorders of pancreatic internal secretion
0.000 0.313 0.686
I15.1 Hypertension secondary to other renal disorders
0.000 0.318 0.682
G37.5 Concentric sclerosis [Balo]
0.680 0.319 0.000
G37.4 Subacute necrotising myelitis
0.680 0.319 0.000
G37.2 Central pontine myelinolysis
0.680 0.319 0.000
G37.1 Central demyelination of corpus callosum
0.680 0.319 0.000
G37.0 Diffuse sclerosis
0.680 0.319 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.326 0.674
E13.8 With unspecified complications
0.000 0.329 0.671
E13.7 With multiple complications
0.000 0.329 0.671
E13.6 With other specified complications
0.000 0.329 0.671
E13.5 With peripheral circulatory complications
0.000 0.329 0.671
E13.4 With neurological complications
0.000 0.329 0.671
E13.3 With ophthalmic complications
0.000 0.329 0.671
E13.2 With renal complications
0.000 0.329 0.671
E13.1 With ketoacidosis
0.000 0.329 0.671
E13.0 With coma
0.000 0.329 0.671
I22.8 Subsequent myocardial infarction of other sites
0.000 0.339 0.661
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.341 0.659
I12.9 Hypertensive renal disease without renal failure
0.000 0.345 0.655
E78.4 Other hyperlipidaemia
0.000 0.346 0.654
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.347 0.653
L42 Pityriasis rosea
0.000 0.348 0.652
E79 Disorders of purine and pyrimidine metabolism
0.000 0.351 0.649
E77 Disorders of glycoprotein metabolism
0.000 0.352 0.648
E76 Disorders of glycosaminoglycan metabolism
0.000 0.352 0.648
E72 Other disorders of amino-acid metabolism
0.000 0.352 0.648
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.352 0.648
E70 Disorders of aromatic amino-acid metabolism
0.000 0.352 0.648
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.352 0.648
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.360 0.639
I23.8 Other current complications following acute myocardial infarction
0.000 0.363 0.637
E85.9 Amyloidosis, unspecified
0.000 0.368 0.632
I11 Hypertensive heart disease
0.000 0.371 0.629
L44 Other papulosquamous disorders
0.000 0.371 0.629
L41 Parapsoriasis
0.000 0.371 0.629
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.371 0.629
E11.4 With neurological complications
0.000 0.381 0.619
I20.1 Angina pectoris with documented spasm
0.000 0.383 0.617
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.385 0.614
I13 Hypertensive heart and renal disease
0.000 0.387 0.613
L43.3 Subacute (active) lichen planus
0.000 0.391 0.609
L43.2 Lichenoid drug reaction
0.000 0.391 0.609
L43.1 Bullous lichen planus
0.000 0.391 0.609
L43.0 Hypertrophic lichen planus
0.000 0.391 0.609
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.394 0.606
E16.2 Hypoglycaemia, unspecified
0.000 0.401 0.599
E84 Cystic fibrosis
0.000 0.406 0.594
I25.4 Coronary artery aneurysm
0.000 0.418 0.582
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.423 0.577
E00 Congenital iodine-deficiency syndrome
0.000 0.423 0.577
E40-E46 Malnutrition
0.000 0.423 0.577
Chapter IX Diseases of the circulatory system
0.000 0.430 0.570
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.435 0.565
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.435 0.565
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.435 0.565
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.437 0.562
E15 Nondiabetic hypoglycaemic coma
0.000 0.440 0.559
E11.3 With ophthalmic complications
0.000 0.447 0.553
E03.5 Myxoedema coma
0.000 0.454 0.546
E03.4 Atrophy of thyroid (acquired)
0.000 0.454 0.546
E03.3 Postinfectious hypothyroidism
0.000 0.454 0.546
E03.1 Congenital hypothyroidism without goitre
0.000 0.454 0.546
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.454 0.546
E85.4 Organ-limited amyloidosis
0.000 0.455 0.545
E16.1 Other hypoglycaemia
0.000 0.460 0.540
I15.8 Other secondary hypertension
0.000 0.461 0.539
I15.2 Hypertension secondary to endocrine disorders
0.000 0.461 0.539
I15.0 Renovascular hypertension
0.000 0.461 0.539
E05.5 Thyroid crisis or storm
0.000 0.461 0.539
E05.4 Thyrotoxicosis factitia
0.000 0.461 0.539
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.461 0.539
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.461 0.539
E89.3 Postprocedural hypopituitarism
0.000 0.461 0.539
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.464 0.536
E85.8 Other amyloidosis
0.000 0.465 0.534
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.465 0.534
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.465 0.534
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.465 0.534
I15.9 Seconday hypertension, unspecified
0.000 0.471 0.529
E73 Lactose intolerance
0.000 0.472 0.528
E07 Other disorders of thyroid
0.000 0.474 0.526
E85.3 Secondary systemic amyloidosis
0.000 0.477 0.523
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.477 0.522
E11.8 With unspecified complications
0.000 0.480 0.519
I24.1 Dressler's syndrome
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.486 0.514
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.494 0.505
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.494 0.505
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.494 0.505
E74.2 Disorders of galactose metabolism
0.000 0.494 0.505
E74.1 Disorders of fructose metabolism
0.000 0.494 0.505
E74.0 Glycogen storage disease
0.000 0.494 0.505
I12.0 Hypertensive renal disease with renal failure
0.000 0.497 0.503
G36.0 Neuromyelitis optica [Devic]
0.498 0.502 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.502 0.498
G36.9 Acute disseminated demyelination, unspecified
0.495 0.505 0.000
G36.8 Other specified acute disseminated demyelination
0.495 0.505 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.495 0.505 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.508 0.492
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.508 0.492
E16.4 Abnormal secretion of gastrin
0.000 0.508 0.492
E16.3 Increased secretion of glucagon
0.000 0.508 0.492
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.510 0.490
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.512 0.488
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.513 0.487
E06 Thyroiditis
0.000 0.519 0.481
E88 Other metabolic disorders
0.000 0.529 0.471
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.534 0.466
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.534 0.465
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.534 0.465
E79.1 Lesch-Nyhan syndrome
0.000 0.534 0.465
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.535 0.465
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.535 0.465
E70.3 Albinism
0.000 0.535 0.465
E70.2 Disorders of tyrosine metabolism
0.000 0.535 0.465
E70.1 Other hyperphenylalaninaemias
0.000 0.535 0.465
E70.0 Classical phenylketonuria
0.000 0.535 0.465
E71.3 Disorders of fatty-acid metabolism
0.000 0.535 0.465
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.535 0.465
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.535 0.465
E71.0 Maple-syrup-urine disease
0.000 0.535 0.465
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.535 0.465
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.535 0.465
E72.5 Disorders of glycine metabolism
0.000 0.535 0.465
E72.4 Disorders of ornithine metabolism
0.000 0.535 0.465
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.535 0.465
E72.2 Disorders of urea cycle metabolism
0.000 0.535 0.465
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.535 0.465
E72.0 Disorders of amino-acid transport
0.000 0.535 0.465
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.535 0.465
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.535 0.465
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.535 0.465
E76.2 Other mucopolysaccharidoses
0.000 0.535 0.465
E76.1 Mucopolysaccharidosis, type II
0.000 0.535 0.465
E76.0 Mucopolysaccharidosis, type I
0.000 0.535 0.465
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.535 0.465
E77.8 Other disorders of glycoprotein metabolism
0.000 0.535 0.465
E77.1 Defects in glycoprotein degradation
0.000 0.535 0.465
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.535 0.465
E75.6 Lipid storage disorder, unspecified
0.000 0.541 0.458
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.541 0.458
E75.3 Sphingolipidosis, unspecified
0.000 0.541 0.458
E75.2 Other sphingolipidosis
0.000 0.541 0.458
E75.1 Other gangliosidosis
0.000 0.541 0.458
E75.0 GM2 gangliosidosis
0.000 0.541 0.458
E83 Disorders of mineral metabolism
0.301 0.548 0.151
L41.9 Parapsoriasis, unspecified
0.000 0.549 0.451
L41.8 Other parapsoriasis
0.000 0.549 0.451
L41.5 Retiform parapsoriasis
0.000 0.549 0.451
L41.4 Large plaque parapsoriasis
0.000 0.549 0.451
L41.3 Small plaque parapsoriasis
0.000 0.549 0.451
L41.2 Lymphomatoid papulosis
0.000 0.549 0.451
L41.1 Pityriasis lichenoides chronica
0.000 0.549 0.451
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.549 0.451
L44.9 Papulosquamous disorder, unspecified
0.000 0.549 0.451
L44.8 Other specified papulosquamous disorders
0.000 0.549 0.451
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.549 0.451
L44.3 Lichen ruber moniliformis
0.000 0.549 0.451
L44.2 Lichen striatus
0.000 0.549 0.451
L44.1 Lichen nitidus
0.000 0.549 0.451
L44.0 Pityriasis rubra pilaris
0.000 0.549 0.451
E75.5 Other lipid storage disorders
0.000 0.550 0.450
E65-E68 Obesity and other hyperalimentation
0.000 0.557 0.443
E05.8 Other thyrotoxicosis
0.000 0.558 0.442
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.559 0.441
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.559 0.441
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.559 0.441
E89.5 Postprocedural testicular hypofunction
0.000 0.559 0.441
E89.1 Postprocedural hypoinsulinaemia
0.000 0.559 0.441
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.560 0.440
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.560 0.440
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.560 0.440
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.560 0.440
E84.8 Cystic fibrosis with other manifestations
0.000 0.574 0.426
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.574 0.426
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.574 0.426
E89.4 Postprocedural ovarian failure
0.000 0.574 0.426
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.586 0.414
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.586 0.414
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.586 0.414
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.586 0.414
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.586 0.414
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.586 0.414
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.586 0.414
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.586 0.414
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.586 0.414
E45 Retarded development following protein-energy malnutrition
0.000 0.586 0.414
E43 Unspecified severe protein-energy malnutrition
0.000 0.586 0.414
E42 Marasmic kwashiorkor
0.000 0.586 0.414
E41 Nutritional marasmus
0.000 0.586 0.414
E40 Kwashiorkor
0.000 0.586 0.414
I00-I02 Acute rheumatic fever
0.000 0.591 0.408
E50-E64 Other nutritional deficiencies
0.000 0.599 0.401
E89.2 Postprocedural hypoparathyroidism
0.000 0.599 0.401
K90 Intestinal malabsorption
0.000 0.605 0.395
E73.8 Other lactose intolerance
0.000 0.621 0.378
E73.1 Secondary lactase deficiency
0.000 0.621 0.378
E73.0 Congenital lactase deficiency
0.000 0.621 0.378
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.621 0.379
E07.1 Dyshormogenetic goitre
0.000 0.622 0.377
E07.0 Hypersecretion of calcitonin
0.000 0.622 0.377
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.623 0.376
E07.8 Other specified disorders of thyroid
0.000 0.624 0.376
E88.2 Lipomatosis, not elsewhere classified
0.000 0.625 0.375
E84.9 Cystic fibrosis, unspecified
0.001 0.628 0.371
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.630 0.369
E80.6 Other disorders of bilirubin metabolism
0.000 0.632 0.368
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.648 0.351
E80.5 Crigler-Najjar syndrome
0.000 0.648 0.351
E80.3 Defects of catalase and peroxydase
0.000 0.648 0.351
E80.2 Other porphyria
0.000 0.648 0.351
E80.1 Porphyria cutanea tarda
0.000 0.648 0.351
E80.0 Hereditary erythropoietic porphyria
0.000 0.648 0.351
E88.8 Other specified metabolic disorders
0.000 0.652 0.348
E06.5 Other chronic thyroiditis
0.000 0.655 0.345
E06.4 Drug-induced thyroiditis
0.000 0.655 0.345
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.655 0.345
E06.1 Subacute thyroiditis
0.000 0.655 0.345
E06.0 Acute thyroiditis
0.000 0.655 0.345
E88.9 Metabolic disorder, unspecified
0.000 0.662 0.338
E46 Unspecified protein-energy malnutrition
0.000 0.662 0.338
E88.3 Tumour lysis syndrome
0.000 0.665 0.334
E07.9 Disorder of thyroid, unspecified
0.000 0.671 0.329
E06.9 Thyroiditis, unspecified
0.000 0.672 0.328
E83.9 Disorder of mineral metabolism, unspecified
0.216 0.676 0.108
E83.8 Other disorders of mineral metabolism
0.216 0.676 0.108
E83.2 Disorders of zinc metabolism
0.216 0.676 0.108
E83.0 Disorders of copper metabolism
0.216 0.676 0.108
E67 Other hyperalimentation
0.000 0.682 0.318
E68 Sequelae of hyperalimentation
0.000 0.682 0.318
E65 Localised adiposity
0.000 0.691 0.309
E03.8 Other specified hypothyroidism
0.001 0.696 0.303
E83.3 Disorders of phosphorus metabolism
0.248 0.698 0.054
E61 Deficiency of other nutrient elements
0.000 0.700 0.300
E44.1 Mild protein-energy malnutrition
0.000 0.703 0.297
E44.0 Moderate protein-energy malnutrition
0.000 0.703 0.297
I02 Rheumatic chorea
0.000 0.707 0.293
I01 Rheumatic fever with heart involvement
0.000 0.707 0.293
I00 Rheumatic fever without mention of heart involvement
0.000 0.707 0.293
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.712 0.287
E63 Other nutritional deficiencies
0.000 0.712 0.287
E56 Other vitamin deficiencies
0.000 0.712 0.287
E51 Thiamine deficiency
0.000 0.712 0.287
E50 Vitamin A deficiency
0.000 0.712 0.287
E60 Dietary zinc deficiency
0.000 0.712 0.287
E59 Dietary selenium deficiency
0.000 0.712 0.287
E58 Dietary calcium deficiency
0.000 0.712 0.287
E54 Ascorbic acid deficiency
0.000 0.712 0.287
E52 Niacin deficiency [pellagra]
0.000 0.712 0.287
K90.9 Intestinal malabsorption, unspecified
0.000 0.715 0.284
K90.8 Other intestinal malabsorption
0.000 0.717 0.283
K90.3 Pancreatic steatorrhoea
0.000 0.717 0.283
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.717 0.283
K90.1 Tropical sprue
0.000 0.717 0.283
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.723 0.277
E06.3 Autoimmune thyroiditis
0.000 0.725 0.275
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.727 0.272
E20-E35 Disorders of other endocrine glands
0.000 0.728 0.272
E73.9 Lactose intolerance, unspecified
0.001 0.741 0.258
E89.0 Postprocedural hypothyroidism
0.000 0.742 0.258
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.746 0.254
E61.1 Iron deficiency
0.000 0.765 0.235
E55 Vitamin D deficiency
0.000 0.771 0.228
E67.8 Other specified hyperalimentation
0.000 0.772 0.228
E67.3 Hypervitaminosis D
0.000 0.772 0.228
E67.2 Megavitamin-B6 syndrome
0.000 0.772 0.228
E67.1 Hypercarotenaemia
0.000 0.772 0.228
E67.0 Hypervitaminosis A
0.000 0.772 0.228
E23 Hypofunction and other disorders of pituitary gland
0.000 0.774 0.226
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.778 0.221
E22 Hyperfunction of pituitary gland
0.000 0.782 0.218
E61.9 Deficiency of nutrient element, unspecified
0.000 0.784 0.215
E61.8 Deficiency of other specified nutrient elements
0.000 0.784 0.215
E61.7 Deficiency of multiple nutrient elements
0.000 0.784 0.215
E61.6 Vanadium deficiency
0.000 0.784 0.215
E61.5 Molybdenum deficiency
0.000 0.784 0.215
E61.4 Chromium deficiency
0.000 0.784 0.215
E61.3 Manganese deficiency
0.000 0.784 0.215
E61.0 Copper deficiency
0.000 0.784 0.215
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.790 0.210
I01.8 Other acute rheumatic heart disease
0.000 0.790 0.210
I01.2 Acute rheumatic myocarditis
0.000 0.790 0.210
I01.1 Acute rheumatic endocarditis
0.000 0.790 0.210
I01.0 Acute rheumatic pericarditis
0.000 0.790 0.210
I02.9 Rheumatic chorea without heart involvement
0.000 0.790 0.210
I02.0 Rheumatic chorea with heart involvement
0.000 0.790 0.210
E61.2 Magnesium deficiency
0.000 0.793 0.206
E50.9 Vitamin A deficiency, unspecified
0.000 0.793 0.206
E50.8 Other manifestations of vitamin A deficiency
0.000 0.793 0.206
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.793 0.206
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.793 0.206
E50.5 Vitamin A deficiency with night blindness
0.000 0.793 0.206
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.793 0.206
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.793 0.206
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.793 0.206
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.793 0.206
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.793 0.206
E51.9 Thiamine deficiency, unspecified
0.000 0.793 0.206
E51.8 Other manifestations of thiamine deficiency
0.000 0.793 0.206
E51.2 Wernicke's encephalopathy
0.000 0.793 0.206
E51.1 Beriberi
0.000 0.793 0.206
E56.9 Vitamin deficiency, unspecified
0.000 0.793 0.206
E56.8 Deficiency of other vitamins
0.000 0.793 0.206
E56.1 Deficiency of vitamin K
0.000 0.793 0.206
E56.0 Deficiency of vitamin E
0.000 0.793 0.206
E63.9 Nutritional deficiency, unspecified
0.000 0.793 0.206
E63.8 Other specified nutritional deficiencies
0.000 0.793 0.206
E63.1 Imbalance of constituents of food intake
0.000 0.793 0.206
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.793 0.206
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.793 0.206
E64.8 Sequelae of other nutritional deficiencies
0.000 0.793 0.206
E64.3 Sequelae of rickets
0.000 0.793 0.206
E64.2 Sequelae of vitamin C deficiency
0.000 0.793 0.206
E64.1 Sequelae of vitamin A deficiency
0.000 0.793 0.206
E64.0 Sequelae of protein-energy malnutrition
0.000 0.793 0.206
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.805 0.195
E32 Diseases of thymus
0.000 0.805 0.195
E31 Polyglandular dysfunction
0.000 0.805 0.195
E30 Disorders of puberty, not elsewhere classified
0.000 0.805 0.195
E25 Adrenogenital disorders
0.000 0.805 0.195
E83.4 Disorders of magnesium metabolism
0.091 0.805 0.104
E26 Hyperaldosteronism
0.000 0.809 0.191
E23.6 Other disorders of pituitary gland
0.000 0.810 0.190
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.814 0.186
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.814 0.186
E23.2 Diabetes insipidus
0.000 0.815 0.185
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.816 0.184
E24 Cushing's syndrome
0.000 0.818 0.182
E29 Testicular dysfunction
0.000 0.819 0.181
E20 Hypoparathyroidism
0.000 0.822 0.178
E23.7 Disorder of pituitary gland, unspecified
0.000 0.828 0.172
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.831 0.168
E28 Ovarian dysfunction
0.000 0.835 0.164
E55.0 Rickets, active
0.000 0.836 0.164
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.838 0.162
E23.1 Drug-induced hypopituitarism
0.000 0.838 0.162
I28 Other diseases of pulmonary vessels
0.001 0.842 0.157
E22.1 Hyperprolactinaemia
0.000 0.843 0.157
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.844 0.156
E22.8 Other hyperfunction of pituitary gland
0.000 0.844 0.156
E80.4 Gilbert's syndrome
0.000 0.847 0.153
E21.3 Hyperparathyroidism, unspecified
0.000 0.855 0.145
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.857 0.143
E22.0 Acromegaly and pituitary gigantism
0.000 0.858 0.141
E34 Other endocrine disorders
0.000 0.859 0.141
E25.9 Adrenogenital disorder, unspecified
0.000 0.860 0.140
E25.8 Other adrenogenital disorders
0.000 0.860 0.140
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.860 0.140
E30.9 Disorder of puberty, unspecified
0.000 0.860 0.140
E30.8 Other disorders of puberty
0.000 0.860 0.140
E30.1 Precocious puberty
0.000 0.860 0.140
E30.0 Delayed puberty
0.000 0.860 0.140
E31.9 Polyglandular dysfunction, unspecified
0.000 0.860 0.140
E31.8 Other polyglandular dysfunction
0.000 0.860 0.140
E31.1 Polyglandular hyperfunction
0.000 0.860 0.140
E31.0 Autoimmune polyglandular failure
0.000 0.860 0.140
E32.9 Disease of thymus, unspecified
0.000 0.860 0.140
E32.8 Other diseases of thymus
0.000 0.860 0.140
E32.1 Abscess of thymus
0.000 0.860 0.140
E32.0 Persistent hyperplasia of thymus
0.000 0.860 0.140
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.860 0.140
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.860 0.140
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.860 0.140
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.862 0.138
E26.9 Hyperaldosteronism, unspecified
0.000 0.863 0.137
E26.8 Other hyperaldosteronism
0.000 0.863 0.137
E26.1 Secondary hyperaldosteronism
0.000 0.863 0.137
I05-I09 Chronic rheumatic heart diseases
0.000 0.864 0.136
E26.0 Primary hyperaldosteronism
0.000 0.866 0.133
E83.5 Disorders of calcium metabolism
0.103 0.867 0.030
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.868 0.132
E21.4 Other specified disorders of parathyroid gland
0.000 0.868 0.132
E21.2 Other hyperparathyroidism
0.000 0.868 0.132
E24.8 Other Cushing's syndrome
0.000 0.869 0.131
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.869 0.131
E24.3 Ectopic ACTH syndrome
0.000 0.869 0.131
E24.2 Drug-induced Cushing's syndrome
0.000 0.869 0.131
E24.1 Nelson's syndrome
0.000 0.869 0.131
E24.0 Pituitary-dependent Cushing's disease
0.000 0.869 0.131
E29.9 Testicular dysfunction, unspecified
0.000 0.870 0.130
E29.8 Other testicular dysfunction
0.000 0.870 0.130
E29.0 Testicular hyperfunction
0.000 0.870 0.130

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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