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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094548
log Bayes Factor = 92.5874
Chromosome 6   position 29,355,202  (GRCh37) Explore rs3094548 on Ensembl!
Variant rs3094548 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.007 0.993
K51.9 Ulcerative colitis, unspecified
0.990 0.010 0.000
E10.2 With renal complications
0.000 0.018 0.982
E03 Other hypothyroidism
0.000 0.023 0.977
K51 Ulcerative colitis
0.976 0.024 0.000
K51.4 Pseudopolyposis of colon
0.964 0.036 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.037 0.963
R31 Unspecified haematuria
0.953 0.047 0.000
E10.4 With neurological complications
0.000 0.053 0.947
E13 Other specified diabetes mellitus
0.000 0.067 0.933
K51.3 Ulcerative (chronic) rectosigmoiditis
0.915 0.085 0.000
E13.9 Without complications
0.000 0.123 0.877
K90 Intestinal malabsorption
0.000 0.172 0.828
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.176 0.824
E10.0 With coma
0.000 0.176 0.824
E14.9 Without complications
0.000 0.181 0.819
E10.6 With other specified complications
0.000 0.218 0.782
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.219 0.781
K90.9 Intestinal malabsorption, unspecified
0.000 0.220 0.780
E05.8 Other thyrotoxicosis
0.000 0.225 0.775
E14.6 With other specified complications
0.000 0.225 0.775
E10.7 With multiple complications
0.000 0.229 0.771
E10.5 With peripheral circulatory complications
0.000 0.230 0.770
K51.5 Mucosal proctocolitis
0.766 0.234 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.760 0.240 0.000
E14.0 With coma
0.000 0.260 0.740
E14.1 With ketoacidosis
0.000 0.262 0.738
E14.2 Withrenal complications
0.000 0.272 0.728
E20-E35 Disorders of other endocrine glands
0.000 0.277 0.723
E14.4 With neurological complications
0.000 0.279 0.721
E14.5 With peripheral circulatory complications
0.000 0.281 0.719
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K51.2 Ulcerative (chronic) proctitis
0.715 0.285 0.000
E14.7 With multiple complications
0.000 0.285 0.715
E13.3 With ophthalmic complications
0.000 0.293 0.707
E16.1 Other hypoglycaemia
0.000 0.297 0.703
E03.5 Myxoedema coma
0.000 0.299 0.700
E03.4 Atrophy of thyroid (acquired)
0.000 0.299 0.700
E03.3 Postinfectious hypothyroidism
0.000 0.299 0.700
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.306 0.694
E27 Other disorders of adrenal gland
0.000 0.331 0.669
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.331 0.669
E13.8 With unspecified complications
0.000 0.331 0.669
E13.7 With multiple complications
0.000 0.331 0.669
E13.6 With other specified complications
0.000 0.331 0.669
E13.5 With peripheral circulatory complications
0.000 0.331 0.669
E13.4 With neurological complications
0.000 0.331 0.669
E13.2 With renal complications
0.000 0.331 0.669
E13.1 With ketoacidosis
0.000 0.331 0.669
E13.0 With coma
0.000 0.331 0.669
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.333 0.667
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.336 0.664
E03.1 Congenital hypothyroidism without goitre
0.000 0.336 0.664
E10.8 With unspecified complications
0.000 0.338 0.662
E14.8 With unspecified complications
0.000 0.338 0.662
E07 Other disorders of thyroid
0.000 0.340 0.660
E40-E46 Malnutrition
0.000 0.342 0.658
E27.1 Primary adrenocortical insufficiency
0.000 0.348 0.652
E50-E64 Other nutritional deficiencies
0.000 0.374 0.626
E24 Cushing's syndrome
0.000 0.401 0.599
E20 Hypoparathyroidism
0.000 0.402 0.598
K90.3 Pancreatic steatorrhoea
0.000 0.406 0.594
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.406 0.594
K90.1 Tropical sprue
0.000 0.406 0.594
E03.8 Other specified hypothyroidism
0.000 0.408 0.592
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.409 0.591
E29 Testicular dysfunction
0.000 0.411 0.589
E11 Non-insulin-dependent diabetes mellitus
0.000 0.429 0.571
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.435 0.564
K90.8 Other intestinal malabsorption
0.000 0.441 0.559
E21.3 Hyperparathyroidism, unspecified
0.000 0.443 0.557
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.538 0.462 0.000
E83 Disorders of mineral metabolism
0.538 0.462 0.000
E25 Adrenogenital disorders
0.000 0.462 0.538
E31 Polyglandular dysfunction
0.000 0.470 0.530
E11.1 With ketoacidosis
0.000 0.476 0.524
E61 Deficiency of other nutrient elements
0.000 0.477 0.523
K51.8 Other ulcerative colitis
0.521 0.479 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.481 0.518
E32 Diseases of thymus
0.000 0.481 0.518
E30 Disorders of puberty, not elsewhere classified
0.000 0.481 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E20.9 Hypoparathyroidism, unspecified
0.000 0.492 0.508
E83.3 Disorders of phosphorus metabolism
0.507 0.493 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.500 0.499 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.502 0.498
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.506 0.494
E11.6 With other specified complications
0.000 0.510 0.490
E51 Thiamine deficiency
0.000 0.519 0.480
E27.5 Adrenomedullary hyperfunction
0.000 0.520 0.480
E27.0 Other adrenocortical overactivity
0.000 0.520 0.480
E29.1 Testicular hypofunction
0.000 0.520 0.480
E27.8 Other specified disorders of adrenal gland
0.000 0.526 0.474
E07.1 Dyshormogenetic goitre
0.000 0.526 0.473
E07.0 Hypersecretion of calcitonin
0.000 0.526 0.473
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.528 0.472
E45 Retarded development following protein-energy malnutrition
0.000 0.528 0.472
E43 Unspecified severe protein-energy malnutrition
0.000 0.528 0.472
E42 Marasmic kwashiorkor
0.000 0.528 0.472
E41 Nutritional marasmus
0.000 0.528 0.472
E40 Kwashiorkor
0.000 0.528 0.472
E21.4 Other specified disorders of parathyroid gland
0.000 0.531 0.469
E27.9 Disorder of adrenal gland, unspecified
0.000 0.538 0.461
E24.0 Pituitary-dependent Cushing's disease
0.000 0.539 0.461
E07.9 Disorder of thyroid, unspecified
0.000 0.541 0.459
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.551 0.449
E50 Vitamin A deficiency
0.000 0.551 0.449
E60 Dietary zinc deficiency
0.000 0.551 0.449
E59 Dietary selenium deficiency
0.000 0.551 0.449
E52 Niacin deficiency [pellagra]
0.000 0.551 0.449
E11.3 With ophthalmic complications
0.000 0.554 0.446
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.555 0.445
E29.9 Testicular dysfunction, unspecified
0.000 0.556 0.444
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.559 0.441
E54 Ascorbic acid deficiency
0.000 0.560 0.440
E24.8 Other Cushing's syndrome
0.000 0.560 0.440
E07.8 Other specified disorders of thyroid
0.000 0.566 0.434
E56 Other vitamin deficiencies
0.000 0.569 0.431
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.570 0.430
E24.3 Ectopic ACTH syndrome
0.000 0.570 0.430
E24.1 Nelson's syndrome
0.000 0.570 0.430
E34 Other endocrine disorders
0.000 0.570 0.429
E20.8 Other hypoparathyroidism
0.000 0.571 0.428
E20.1 Pseudohypoparathyroidism
0.000 0.571 0.428
E20.0 Idiopathic hypoparathyroidism
0.000 0.571 0.428
E61.1 Iron deficiency
0.000 0.571 0.429
E83.9 Disorder of mineral metabolism, unspecified
0.427 0.573 0.000
E11.7 With multiple complications
0.000 0.574 0.426
E29.8 Other testicular dysfunction
0.000 0.577 0.423
E29.0 Testicular hyperfunction
0.000 0.577 0.423
E63 Other nutritional deficiencies
0.000 0.578 0.422
E11.8 With unspecified complications
0.000 0.579 0.421
E55 Vitamin D deficiency
0.000 0.587 0.413
E46 Unspecified protein-energy malnutrition
0.000 0.588 0.412
E61.2 Magnesium deficiency
0.000 0.591 0.409
E24.9 Cushing's syndrome, unspecified
0.000 0.594 0.406
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.595 0.405
E58 Dietary calcium deficiency
0.000 0.603 0.397
E06 Thyroiditis
0.000 0.604 0.396
E11.2 With renal complications
0.000 0.604 0.396
E21.2 Other hyperparathyroidism
0.000 0.605 0.395
E31.0 Autoimmune polyglandular failure
0.000 0.608 0.392
E83.8 Other disorders of mineral metabolism
0.386 0.614 0.000
E83.2 Disorders of zinc metabolism
0.386 0.614 0.000
E83.0 Disorders of copper metabolism
0.386 0.614 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.614 0.386
E25.8 Other adrenogenital disorders
0.000 0.614 0.386
E31.9 Polyglandular dysfunction, unspecified
0.000 0.620 0.380
E31.8 Other polyglandular dysfunction
0.000 0.620 0.380
E31.1 Polyglandular hyperfunction
0.000 0.620 0.380
E51.2 Wernicke's encephalopathy
0.000 0.624 0.376
E61.9 Deficiency of nutrient element, unspecified
0.000 0.625 0.375
E61.8 Deficiency of other specified nutrient elements
0.000 0.625 0.375
E61.7 Deficiency of multiple nutrient elements
0.000 0.625 0.375
E61.6 Vanadium deficiency
0.000 0.625 0.375
E61.5 Molybdenum deficiency
0.000 0.625 0.375
E61.4 Chromium deficiency
0.000 0.625 0.375
E61.3 Manganese deficiency
0.000 0.625 0.375
E61.0 Copper deficiency
0.000 0.625 0.375
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.627 0.373
E30.9 Disorder of puberty, unspecified
0.000 0.628 0.372
E30.8 Other disorders of puberty
0.000 0.628 0.372
E30.1 Precocious puberty
0.000 0.628 0.372
E30.0 Delayed puberty
0.000 0.628 0.372
E32.9 Disease of thymus, unspecified
0.000 0.628 0.372
E32.8 Other diseases of thymus
0.000 0.628 0.372
E32.1 Abscess of thymus
0.000 0.628 0.372
E32.0 Persistent hyperplasia of thymus
0.000 0.628 0.372
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.628 0.372
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.628 0.372
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.628 0.372
E28 Ovarian dysfunction
0.000 0.633 0.366
M45.X9 Ankylosing spondylitis (Site unspecified)
0.355 0.645 0.000
E53 Deficiency of other B group vitamins
0.000 0.648 0.352
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.649 0.351
E27.2 Addisonian crisis
0.000 0.651 0.349
E83.4 Disorders of magnesium metabolism
0.347 0.653 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.655 0.344
E51.8 Other manifestations of thiamine deficiency
0.000 0.655 0.344
E51.1 Beriberi
0.000 0.655 0.344
E44.1 Mild protein-energy malnutrition
0.000 0.662 0.338
E44.0 Moderate protein-energy malnutrition
0.000 0.662 0.338
C15-C26 Malignant neoplasms of digestive organs
0.000 0.662 0.338
E34.3 Short stature, not elsewhere classified
0.000 0.662 0.337
C15 Malignant neoplasm of oesophagus
0.000 0.665 0.335
E26 Hyperaldosteronism
0.001 0.667 0.332
C25 Malignant neoplasm of pancreas
0.000 0.669 0.331
E11.0 With coma
0.000 0.675 0.325
E50.9 Vitamin A deficiency, unspecified
0.000 0.678 0.322
E50.8 Other manifestations of vitamin A deficiency
0.000 0.678 0.322
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.678 0.322
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.678 0.322
E50.5 Vitamin A deficiency with night blindness
0.000 0.678 0.322
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.678 0.322
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.678 0.322
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.678 0.322
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.678 0.322
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.678 0.322
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.678 0.322
E64.8 Sequelae of other nutritional deficiencies
0.000 0.678 0.322
E64.3 Sequelae of rickets
0.000 0.678 0.322
E64.2 Sequelae of vitamin C deficiency
0.000 0.678 0.322
E64.1 Sequelae of vitamin A deficiency
0.000 0.678 0.322
E64.0 Sequelae of protein-energy malnutrition
0.000 0.678 0.322
E34.9 Endocrine disorder, unspecified
0.000 0.686 0.314
C25.9 Pancreas, unspecified
0.000 0.688 0.312
E56.9 Vitamin deficiency, unspecified
0.000 0.691 0.309
E56.8 Deficiency of other vitamins
0.000 0.691 0.309
E56.0 Deficiency of vitamin E
0.000 0.691 0.309
E34.5 Androgen resistance syndrome
0.000 0.692 0.308
E34.4 Constitutional tall stature
0.000 0.692 0.308
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.692 0.308
E34.1 Other hypersecretion of intestinal hormones
0.000 0.692 0.308
C20 Malignant neoplasm of rectum
0.000 0.692 0.308
C15.4 Middle third of oesophagus
0.000 0.692 0.308
C15.9 Oesophagus, unspecified
0.000 0.694 0.306
E63.8 Other specified nutritional deficiencies
0.000 0.697 0.303
E63.1 Imbalance of constituents of food intake
0.000 0.697 0.303
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.697 0.303
E55.0 Rickets, active
0.000 0.704 0.296
E56.1 Deficiency of vitamin K
0.000 0.709 0.291
C15.5 Lower third of oesophagus
0.000 0.714 0.286
E06.4 Drug-induced thyroiditis
0.000 0.716 0.284
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.716 0.284
E06.0 Acute thyroiditis
0.000 0.716 0.284
E06.1 Subacute thyroiditis
0.000 0.718 0.281
E63.9 Nutritional deficiency, unspecified
0.000 0.724 0.276
E06.9 Thyroiditis, unspecified
0.000 0.726 0.273
C25.0 Head of pancreas
0.000 0.728 0.272
C25.8 Overlapping lesion of pancreas
0.000 0.730 0.270
C25.4 Endocrine pancreas
0.000 0.733 0.267
E34.0 Carcinoid syndrome
0.000 0.734 0.266
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.736 0.264
E28.9 Ovarian dysfunction, unspecified
0.000 0.737 0.263
E28.8 Other ovarian dysfunction
0.000 0.737 0.263
E28.1 Androgen excess
0.000 0.737 0.263
E28.0 Oestrogen excess
0.000 0.737 0.263
E53.9 Vitamin B deficiency, unspecified
0.000 0.740 0.260
E55.9 Vitamin D deficiency, unspecified
0.000 0.740 0.260
E65-E68 Obesity and other hyperalimentation
0.003 0.740 0.257
E11.9 Without complications
0.000 0.746 0.254
E06.5 Other chronic thyroiditis
0.001 0.747 0.252
E53.1 Pyridoxine deficiency
0.000 0.747 0.252
E53.0 Riboflavin deficiency
0.000 0.747 0.252
C25.1 Body of pancreas
0.000 0.751 0.249
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.752 0.248
C15.0 Cervical part of oesophagus
0.000 0.753 0.246
M45 Ankylosing spondylitis
0.245 0.755 0.000
C15.1 Thoracic part of oesophagus
0.000 0.755 0.244
K50-K52 Noninfective enteritis and colitis
0.242 0.758 0.000
C15.8 Overlapping lesion of oesophagus
0.000 0.760 0.240
C15.2 Abdominal part of oesophagus
0.000 0.760 0.240
C25.3 Pancreatic duct
0.000 0.760 0.239
E26.8 Other hyperaldosteronism
0.001 0.761 0.238
E26.1 Secondary hyperaldosteronism
0.001 0.761 0.238
E22 Hyperfunction of pituitary gland
0.000 0.761 0.238
C15.3 Upper third of oesophagus
0.000 0.764 0.236
C25.2 Tail of pancreas
0.000 0.769 0.231
C22.9 Liver, unspecified
0.000 0.772 0.228
C17 Malignant neoplasm of small intestine
0.000 0.773 0.226
C16 Malignant neoplasm of stomach
0.000 0.774 0.225
N40 Hyperplasia of prostate
0.224 0.776 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.778 0.222
C25.7 Other parts of pancreas
0.000 0.778 0.222
C24.0 Extrahepatic bile duct
0.000 0.779 0.221
E28.3 Primary ovarian failure
0.000 0.784 0.216
E34.8 Other specified endocrine disorders
0.001 0.787 0.212
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.207 0.793 0.000
C22.1 Intrahepatic bile duct carcinoma
0.000 0.796 0.204
E26.9 Hyperaldosteronism, unspecified
0.001 0.797 0.203
C16.5 Lesser curvature of stomach, unspecified
0.000 0.797 0.203
C17.0 Duodenum
0.000 0.798 0.202
M45.X2 Ankylosing spondylitis (Cervical region)
0.202 0.798 0.000
K50 Crohn's disease [regional enteritis]
0.199 0.801 0.000
E11.5 With peripheral circulatory complications
0.000 0.807 0.193
E28.2 Polycystic ovarian syndrome
0.000 0.809 0.191
C22.7 Other specified carcinomas of liver
0.000 0.810 0.189
C22.4 Other sarcomas of liver
0.000 0.810 0.189
C22.3 Angiosarcoma of liver
0.000 0.810 0.189
C22.2 Hepatoblastoma
0.000 0.810 0.189
E67 Other hyperalimentation
0.002 0.814 0.184
E68 Sequelae of hyperalimentation
0.002 0.814 0.184
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.814 0.186
C23 Malignant neoplasm of gallbladder
0.000 0.816 0.184
C24.9 Biliary tract, unspecified
0.000 0.817 0.183
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.182 0.818 0.000
C24.8 Overlapping lesion of biliary tract
0.000 0.822 0.178
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.176 0.824 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.176 0.824 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.176 0.824 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.176 0.824 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.176 0.824 0.000
C16.8 Overlapping lesion of stomach
0.000 0.827 0.173
K50.1 Crohn's disease of large intestine
0.173 0.827 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.829 0.171
K50.8 Other Crohn's disease
0.170 0.830 0.000
C16.0 Cardia
0.000 0.832 0.168
C16.1 Fundus of stomach
0.000 0.833 0.167
E23.7 Disorder of pituitary gland, unspecified
0.000 0.836 0.164
E22.1 Hyperprolactinaemia
0.000 0.836 0.164
C17.8 Overlapping lesion of small intestine
0.000 0.837 0.162
C17.3 Meckel's diverticulum
0.000 0.837 0.162
M45.X6 Ankylosing spondylitis (Lumbar region)
0.162 0.838 0.000
C16.6 Greater curvature of stomach, unspecified
0.000 0.839 0.161
E23.1 Drug-induced hypopituitarism
0.000 0.841 0.159
C16.2 Body of stomach
0.000 0.844 0.156
C17.1 Jejunum
0.000 0.844 0.156
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.849 0.151
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.858 0.142
E11.4 With neurological complications
0.000 0.858 0.141
E53.8 Deficiency of other specified B group vitamins
0.000 0.860 0.140
E21.0 Primary hyperparathyroidism
0.000 0.864 0.136
C26.9 Ill-defined sites within the digestive system
0.000 0.866 0.134
E67.8 Other specified hyperalimentation
0.002 0.866 0.132
E67.3 Hypervitaminosis D
0.002 0.866 0.132
E67.2 Megavitamin-B6 syndrome
0.002 0.866 0.132
E67.1 Hypercarotenaemia
0.002 0.866 0.132
E67.0 Hypervitaminosis A
0.002 0.866 0.132
C26.8 Overlapping lesion of digestive system
0.000 0.866 0.133
C26.1 Spleen
0.000 0.866 0.133
C17.9 Small intestine, unspecified
0.000 0.869 0.131
C16.9 Stomach, unspecified
0.000 0.870 0.130
E26.0 Primary hyperaldosteronism
0.001 0.871 0.128
E23.6 Other disorders of pituitary gland
0.000 0.872 0.127
K50.9 Crohn's disease, unspecified
0.128 0.872 0.000
C22.0 Liver cell carcinoma
0.000 0.873 0.126
E22.0 Acromegaly and pituitary gigantism
0.000 0.875 0.125
C16.4 Pylorus
0.000 0.879 0.121
E23.2 Diabetes insipidus
0.000 0.879 0.120
I83 Varicose veins of lower extremities
0.116 0.884 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.891 0.109
C16.3 Pyloric antrum
0.000 0.896 0.104
E65 Localised adiposity
0.003 0.899 0.098
C17.2 Ileum
0.000 0.900 0.100
E06.3 Autoimmune thyroiditis
0.001 0.904 0.095
R30-R39 Symptoms and signs involving the urinary system
0.095 0.905 0.000
C21 Malignant neoplasm of anus and anal canal
0.003 0.906 0.091
K50.0 Crohn's disease of small intestine
0.093 0.906 0.000
R39 Other symptoms and signs involving the urinary system
0.088 0.912 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.088 0.912 0.000
E23.0 Hypopituitarism
0.000 0.918 0.081
I83.0 Varicose veins of lower extremities with ulcer
0.080 0.920 0.000
C26.0 Intestinal tract, part unspecified
0.000 0.924 0.076
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.076 0.924 0.000
E04 Other non-toxic goitre
0.001 0.927 0.072
R34 Anuria and oliguria
0.069 0.931 0.000
C21.2 Cloacogenic zone
0.002 0.933 0.065
C24.1 Ampulla of Vater
0.002 0.934 0.064
C21.8 Overlapping lesion of rectum, anus and anal canal
0.002 0.934 0.064
R36 Urethral discharge
0.065 0.935 0.000
R39.2 Extrarenal uraemia
0.063 0.937 0.000
R30 Pain associated with micturition
0.057 0.943 0.000
R39.0 Extravasation of urine
0.054 0.946 0.000
R33 Retention of urine
0.053 0.947 0.000
E04.8 Other specified non-toxic goitre
0.001 0.947 0.052
K90-K93 Other diseases of the digestive system
0.000 0.948 0.052
I83.1 Varicose veins of lower extremities with inflammation
0.052 0.948 0.000
R39.1 Other difficulties with micturition
0.049 0.951 0.000
M45-M49 Spondylopathies
0.044 0.956 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.957 0.043
C18 Malignant neoplasm of colon
0.000 0.957 0.043
R30.1 Vesical tenesmus
0.041 0.959 0.000
M20.5 Other deformities of toe(s) (acquired)
0.039 0.961 0.000
C18.9 Colon, unspecified
0.000 0.961 0.039
N04.9 Unspecified
0.000 0.962 0.038
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.962 0.038
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.037 0.963 0.000
E83.5 Disorders of calcium metabolism
0.037 0.963 0.000
R30.9 Painful micturition, unspecified
0.036 0.963 0.000
H40.2 Primary angle-closure glaucoma
0.036 0.964 0.000
R30.0 Dysuria
0.036 0.964 0.000
M47.2 Other spondylosis with radiculopathy
0.036 0.964 0.000
M47 Spondylosis
0.036 0.964 0.000
C21.0 Anus, unspecified
0.003 0.966 0.032
N04 Nephrotic syndrome
0.000 0.967 0.033
M47.1 Other spondylosis with myelopathy
0.032 0.968 0.000
M49 Spondylopathies in diseases classified elsewhere
0.031 0.969 0.000
C18.6 Descending colon
0.000 0.969 0.031
C18.1 Appendix
0.000 0.970 0.030
M47.12 Other spondylosis with myelopathy (Cervical region)
0.030 0.970 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.971 0.029
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.029 0.971 0.000
C18.8 Overlapping lesion of colon
0.000 0.972 0.028
E04.9 Non-toxic goitre, unspecified
0.000 0.972 0.028
N04.2 Diffuse membranous glomerulonephritis
0.000 0.972 0.028
C18.4 Transverse colon
0.000 0.972 0.028
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.973 0.027
K93.1 Megacolon in Chagas' disease
0.000 0.973 0.027
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.973 0.027
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.973 0.027
N04.1 Focal and segmental glomerular lesions
0.000 0.973 0.027
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.026 0.974 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.026 0.974 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.026 0.974 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.026 0.974 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.026 0.974 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.026 0.974 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.026 0.974 0.000
N00-N08 Glomerular diseases
0.000 0.974 0.026
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.026 0.974 0.000
C18.0 Caecum
0.000 0.975 0.025
N04.8 Other
0.000 0.976 0.024
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.976 0.024
N04.6 Dense deposit disease
0.000 0.976 0.024
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.976 0.024
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.976 0.024
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.976 0.024
C21.1 Anal canal
0.004 0.976 0.019
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.023 0.977 0.000
N04.0 Minor glomerular abnormality
0.000 0.977 0.023
H47.3 Other disorders of optic disk
0.000 0.977 0.023
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.023 0.977 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.023 0.977 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.023 0.977 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.023 0.977 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.023 0.977 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.023 0.977 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.023 0.977 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.022 0.978 0.000
M49.4 Neuropathic spondylopathy
0.022 0.978 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.022 0.978 0.000
M49.2 Enterobacterial spondylitis
0.022 0.978 0.000
M49.1 Brucella spondylitis
0.022 0.978 0.000
M49.0 Tuberculosis of spine
0.022 0.978 0.000
M48 Other spondylopathies
0.022 0.978 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.022 0.978 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.979 0.021
M49.5 Collapsed vertebra in diseases classified elsewhere
0.021 0.979 0.000
C18.5 Splenic flexure
0.000 0.979 0.021
C18.3 Hepatic flexure
0.000 0.980 0.020
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.980 0.020
J45.9 Asthma, unspecified
0.000 0.980 0.020
N00 Acute nephritic syndrome
0.000 0.980 0.020
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.980 0.020
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.980 0.020
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.980 0.020
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.980 0.020
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.980 0.019
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.019 0.980 0.000
H47.2 Optic atrophy
0.000 0.981 0.019
C83.3 Large cell (diffuse)
0.000 0.981 0.019
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)
0.019 0.981 0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)
0.019 0.981 0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)
0.019 0.981 0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)
0.019 0.981 0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)
0.019 0.981 0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)
0.019 0.981 0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)
0.019 0.981 0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)
0.019 0.981 0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)
0.019 0.981 0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)
0.019 0.981 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.981 0.019
N06 Isolated proteinuria with specified morphological lesion
0.000 0.981 0.019
N01 Rapidly progressive nephritic syndrome
0.000 0.981 0.019
N05 Unspecified nephritic syndrome
0.000 0.982 0.018
C18.7 Sigmoid colon
0.000 0.982 0.018
M48.9 Spondylopathy, unspecified
0.017 0.983 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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